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Network neighborhood for query Sequence : SAP_MOUSE

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SAP_MOUSE
SwissProt Accessions	Q61207, Q60861, Q64006, Q64219	Gene names	Psap, Sgp1
Domain Architecture
Description	Sulfated glycoprotein 1 precursor (SGP-1) (Prosaposin).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SAP_HUMAN
θ value	0 (rank : 1)	NC score	0.979211 (rank : 2)
Query Neighborhood Hits	22	Target Neighborhood Hits	26	Shared Neighborhood Hits	5
SwissProt Accessions	P07602, P07292, P15793, P78538, P78541, P78546, P78547, P78558, Q6IBQ6, Q92739, Q92740, Q92741, Q92742	Gene names	PSAP
Domain Architecture
Description	Proactivator polypeptide precursor [Contains: Saposin A (Protein A); Saposin B-Val; Saposin B (Sphingolipid activator protein 1) (SAP-1) (Cerebroside sulfate activator) (CSAct) (Dispersin) (Sulfatide/GM1 activator); Saposin C (Co-beta-glucosidase) (A1 activator) (Glucosylceramidase activator) (Sphingolipid activator protein 2) (SAP-2); Saposin D (Protein C) (Component C)].

SAP_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	22	Target Neighborhood Hits	22	Shared Neighborhood Hits	22
SwissProt Accessions	Q61207, Q60861, Q64006, Q64219	Gene names	Psap, Sgp1
Domain Architecture
Description	Sulfated glycoprotein 1 precursor (SGP-1) (Prosaposin).

PSPB_MOUSE
θ value	8.36355e-22 (rank : 3)	NC score	0.671588 (rank : 3)
Query Neighborhood Hits	22	Target Neighborhood Hits	8	Shared Neighborhood Hits	5
SwissProt Accessions	P50405	Gene names	Sftpb, Sftp3
Domain Architecture
Description	Pulmonary surfactant-associated protein B precursor (SP-B) (Pulmonary surfactant-associated proteolipid SPL(Phe)).

PSPB_HUMAN
θ value	2.35696e-16 (rank : 4)	NC score	0.632409 (rank : 4)
Query Neighborhood Hits	22	Target Neighborhood Hits	14	Shared Neighborhood Hits	5
SwissProt Accessions	P07988, Q96R04	Gene names	SFTPB, SFTP3
Domain Architecture
Description	Pulmonary surfactant-associated protein B precursor (SP-B) (6 kDa protein) (Pulmonary surfactant-associated proteolipid SPL(Phe)) (18 kDa pulmonary-surfactant protein).

HRX_HUMAN
θ value	0.365318 (rank : 5)	NC score	0.031989 (rank : 12)
Query Neighborhood Hits	22	Target Neighborhood Hits	825	Shared Neighborhood Hits	5
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

TRAIP_HUMAN
θ value	0.365318 (rank : 6)	NC score	0.035405 (rank : 9)
Query Neighborhood Hits	22	Target Neighborhood Hits	780	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BWF2, O00467	Gene names	TRAIP, TRIP
Domain Architecture
Description	TRAF-interacting protein.

ANGL5_HUMAN
θ value	0.47712 (rank : 7)	NC score	0.025159 (rank : 14)
Query Neighborhood Hits	22	Target Neighborhood Hits	56	Shared Neighborhood Hits	2
SwissProt Accessions	Q86XS5, Q86VR9	Gene names	ANGPTL5
Domain Architecture	No domain graphic available
Description	Angiopoietin-related protein 5 precursor (Angiopoietin-like 5).

TRAIP_MOUSE
θ value	0.813845 (rank : 8)	NC score	0.032214 (rank : 11)
Query Neighborhood Hits	22	Target Neighborhood Hits	745	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VIG6, O08854, Q922M8, Q9CPP4	Gene names	Traip, Trip
Domain Architecture
Description	TRAF-interacting protein.

AOAH_HUMAN
θ value	1.38821 (rank : 9)	NC score	0.101128 (rank : 5)
Query Neighborhood Hits	22	Target Neighborhood Hits	10	Shared Neighborhood Hits	5
SwissProt Accessions	P28039, Q53F13	Gene names	AOAH
Domain Architecture
Description	Acyloxyacyl hydrolase precursor (EC 3.1.1.77) [Contains: Acyloxyacyl hydrolase small subunit; Acyloxyacyl hydrolase large subunit].

LIGA_HUMAN
θ value	2.36792 (rank : 10)	NC score	0.046973 (rank : 7)
Query Neighborhood Hits	22	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	P41214, Q9NR27, Q9NSN0, Q9NV18, Q9NZ21	Gene names	LGTN, HCA56
Domain Architecture
Description	Ligatin (Hepatocellular carcinoma-associated antigen 56).

TF2AA_MOUSE
θ value	2.36792 (rank : 11)	NC score	0.032377 (rank : 10)
Query Neighborhood Hits	22	Target Neighborhood Hits	36	Shared Neighborhood Hits	2
SwissProt Accessions	Q99PM3, Q8C812	Gene names	Gtf2a1
Domain Architecture	No domain graphic available
Description	Transcription initiation factor IIA subunit 1 (General transcription factor IIA1) [Contains: Transcription initiation factor IIA alpha chain (TFIIA p35 subunit); Transcription initiation factor IIA beta chain (TFIIA p19 subunit)].

GDIB_HUMAN
θ value	3.0926 (rank : 12)	NC score	0.027179 (rank : 13)
Query Neighborhood Hits	22	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	P50395, O43928, Q9UQM6	Gene names	GDI2, RABGDIB
Domain Architecture
Description	Rab GDP dissociation inhibitor beta (Rab GDI beta) (Guanosine diphosphate dissociation inhibitor 2) (GDI-2).

LIGA_MOUSE
θ value	3.0926 (rank : 13)	NC score	0.045451 (rank : 8)
Query Neighborhood Hits	22	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	Q61211, Q3TDE0, Q3THV5, Q3TTP4, Q8C491, Q8CBF1, Q8CC17, Q8R1I9, Q8R3M5	Gene names	Lgtn
Domain Architecture	No domain graphic available
Description	Ligatin.

PER3_HUMAN
θ value	3.0926 (rank : 14)	NC score	0.016372 (rank : 17)
Query Neighborhood Hits	22	Target Neighborhood Hits	479	Shared Neighborhood Hits	2
SwissProt Accessions	P56645, Q5H8X4, Q969K6, Q96S77, Q96S78, Q9C0J3, Q9NSP9, Q9UGU8	Gene names	PER3
Domain Architecture
Description	Period circadian protein 3 (hPER3).

RBBP6_MOUSE
θ value	3.0926 (rank : 15)	NC score	0.017463 (rank : 16)
Query Neighborhood Hits	22	Target Neighborhood Hits	1014	Shared Neighborhood Hits	5
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

CHD9_HUMAN
θ value	4.03905 (rank : 16)	NC score	0.010055 (rank : 19)
Query Neighborhood Hits	22	Target Neighborhood Hits	343	Shared Neighborhood Hits	5
SwissProt Accessions	Q3L8U1, O15025, Q1WF12, Q6DTK9, Q9H9V7	Gene names	CHD9, KIAA0308, KISH2, PRIC320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Chromatin-related mesenchymal modulator) (CReMM) (Chromatin remodeling factor CHROM1) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha-interacting complex protein 320 kDa) (Kismet homolog 2).

TITIN_HUMAN
θ value	4.03905 (rank : 17)	NC score	0.002740 (rank : 22)
Query Neighborhood Hits	22	Target Neighborhood Hits	2923	Shared Neighborhood Hits	6
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

GDIB_MOUSE
θ value	5.27518 (rank : 18)	NC score	0.024631 (rank : 15)
Query Neighborhood Hits	22	Target Neighborhood Hits	17	Shared Neighborhood Hits	3
SwissProt Accessions	Q61598, Q541Z9, Q8C530, Q9D8M9	Gene names	Gdi2, Gdi3
Domain Architecture
Description	Rab GDP dissociation inhibitor beta (Rab GDI beta) (Guanosine diphosphate dissociation inhibitor 2) (GDI-2) (GDI-3).

CTR1_MOUSE
θ value	6.88961 (rank : 19)	NC score	0.010185 (rank : 18)
Query Neighborhood Hits	22	Target Neighborhood Hits	36	Shared Neighborhood Hits	2
SwissProt Accessions	Q09143, P30824	Gene names	Slc7a1, Atrc1, Rec-1
Domain Architecture
Description	High-affinity cationic amino acid transporter 1 (CAT-1) (CAT1) (System Y+ basic amino acid transporter) (Ecotropic retroviral leukemia receptor) (ERR) (Ecotropic retrovirus receptor).

KCNV2_HUMAN
θ value	8.99809 (rank : 20)	NC score	0.004990 (rank : 21)
Query Neighborhood Hits	22	Target Neighborhood Hits	137	Shared Neighborhood Hits	2
SwissProt Accessions	Q8TDN2	Gene names	KCNV2
Domain Architecture
Description	Potassium voltage-gated channel subfamily V member 2 (Voltage-gated potassium channel subunit Kv8.2).

NDRG4_MOUSE
θ value	8.99809 (rank : 21)	NC score	0.009133 (rank : 20)
Query Neighborhood Hits	22	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BTG7	Gene names	Ndrg4, Ndr4
Domain Architecture	No domain graphic available
Description	Protein NDRG4 (Protein Ndr4).

ZN236_HUMAN
θ value	8.99809 (rank : 22)	NC score	0.000082 (rank : 23)
Query Neighborhood Hits	22	Target Neighborhood Hits	844	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UL36, Q9UL37	Gene names	ZNF236
Domain Architecture	No domain graphic available
Description	Zinc finger protein 236.

AOAH_MOUSE
θ value	θ > 10 (rank : 23)	NC score	0.071050 (rank : 6)
Query Neighborhood Hits	22	Target Neighborhood Hits	6	Shared Neighborhood Hits	2
SwissProt Accessions	O35298	Gene names	Aoah
Domain Architecture	No domain graphic available
Description	Acyloxyacyl hydrolase precursor (EC 3.1.1.77) [Contains: Acyloxyacyl hydrolase small subunit; Acyloxyacyl hydrolase large subunit].

Hits sorted by NC score

SAP_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	22	Target Neighborhood Hits	22	Shared Neighborhood Hits	22
SwissProt Accessions	Q61207, Q60861, Q64006, Q64219	Gene names	Psap, Sgp1
Domain Architecture
Description	Sulfated glycoprotein 1 precursor (SGP-1) (Prosaposin).

SAP_HUMAN
NC score	0.979211 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	22	Target Neighborhood Hits	26	Shared Neighborhood Hits	5
SwissProt Accessions	P07602, P07292, P15793, P78538, P78541, P78546, P78547, P78558, Q6IBQ6, Q92739, Q92740, Q92741, Q92742	Gene names	PSAP
Domain Architecture
Description	Proactivator polypeptide precursor [Contains: Saposin A (Protein A); Saposin B-Val; Saposin B (Sphingolipid activator protein 1) (SAP-1) (Cerebroside sulfate activator) (CSAct) (Dispersin) (Sulfatide/GM1 activator); Saposin C (Co-beta-glucosidase) (A1 activator) (Glucosylceramidase activator) (Sphingolipid activator protein 2) (SAP-2); Saposin D (Protein C) (Component C)].

PSPB_MOUSE
NC score	0.671588 (rank : 3)	θ value	8.36355e-22 (rank : 3)
Query Neighborhood Hits	22	Target Neighborhood Hits	8	Shared Neighborhood Hits	5
SwissProt Accessions	P50405	Gene names	Sftpb, Sftp3
Domain Architecture
Description	Pulmonary surfactant-associated protein B precursor (SP-B) (Pulmonary surfactant-associated proteolipid SPL(Phe)).

PSPB_HUMAN
NC score	0.632409 (rank : 4)	θ value	2.35696e-16 (rank : 4)
Query Neighborhood Hits	22	Target Neighborhood Hits	14	Shared Neighborhood Hits	5
SwissProt Accessions	P07988, Q96R04	Gene names	SFTPB, SFTP3
Domain Architecture
Description	Pulmonary surfactant-associated protein B precursor (SP-B) (6 kDa protein) (Pulmonary surfactant-associated proteolipid SPL(Phe)) (18 kDa pulmonary-surfactant protein).

AOAH_HUMAN
NC score	0.101128 (rank : 5)	θ value	1.38821 (rank : 9)
Query Neighborhood Hits	22	Target Neighborhood Hits	10	Shared Neighborhood Hits	5
SwissProt Accessions	P28039, Q53F13	Gene names	AOAH
Domain Architecture
Description	Acyloxyacyl hydrolase precursor (EC 3.1.1.77) [Contains: Acyloxyacyl hydrolase small subunit; Acyloxyacyl hydrolase large subunit].

AOAH_MOUSE
NC score	0.071050 (rank : 6)	θ value	θ > 10 (rank : 23)
Query Neighborhood Hits	22	Target Neighborhood Hits	6	Shared Neighborhood Hits	2
SwissProt Accessions	O35298	Gene names	Aoah
Domain Architecture	No domain graphic available
Description	Acyloxyacyl hydrolase precursor (EC 3.1.1.77) [Contains: Acyloxyacyl hydrolase small subunit; Acyloxyacyl hydrolase large subunit].

LIGA_HUMAN
NC score	0.046973 (rank : 7)	θ value	2.36792 (rank : 10)
Query Neighborhood Hits	22	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	P41214, Q9NR27, Q9NSN0, Q9NV18, Q9NZ21	Gene names	LGTN, HCA56
Domain Architecture
Description	Ligatin (Hepatocellular carcinoma-associated antigen 56).

LIGA_MOUSE
NC score	0.045451 (rank : 8)	θ value	3.0926 (rank : 13)
Query Neighborhood Hits	22	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	Q61211, Q3TDE0, Q3THV5, Q3TTP4, Q8C491, Q8CBF1, Q8CC17, Q8R1I9, Q8R3M5	Gene names	Lgtn
Domain Architecture	No domain graphic available
Description	Ligatin.

TRAIP_HUMAN
NC score	0.035405 (rank : 9)	θ value	0.365318 (rank : 6)
Query Neighborhood Hits	22	Target Neighborhood Hits	780	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BWF2, O00467	Gene names	TRAIP, TRIP
Domain Architecture
Description	TRAF-interacting protein.

TF2AA_MOUSE
NC score	0.032377 (rank : 10)	θ value	2.36792 (rank : 11)
Query Neighborhood Hits	22	Target Neighborhood Hits	36	Shared Neighborhood Hits	2
SwissProt Accessions	Q99PM3, Q8C812	Gene names	Gtf2a1
Domain Architecture	No domain graphic available
Description	Transcription initiation factor IIA subunit 1 (General transcription factor IIA1) [Contains: Transcription initiation factor IIA alpha chain (TFIIA p35 subunit); Transcription initiation factor IIA beta chain (TFIIA p19 subunit)].

TRAIP_MOUSE
NC score	0.032214 (rank : 11)	θ value	0.813845 (rank : 8)
Query Neighborhood Hits	22	Target Neighborhood Hits	745	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VIG6, O08854, Q922M8, Q9CPP4	Gene names	Traip, Trip
Domain Architecture
Description	TRAF-interacting protein.

HRX_HUMAN
NC score	0.031989 (rank : 12)	θ value	0.365318 (rank : 5)
Query Neighborhood Hits	22	Target Neighborhood Hits	825	Shared Neighborhood Hits	5
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

GDIB_HUMAN
NC score	0.027179 (rank : 13)	θ value	3.0926 (rank : 12)
Query Neighborhood Hits	22	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	P50395, O43928, Q9UQM6	Gene names	GDI2, RABGDIB
Domain Architecture
Description	Rab GDP dissociation inhibitor beta (Rab GDI beta) (Guanosine diphosphate dissociation inhibitor 2) (GDI-2).

ANGL5_HUMAN
NC score	0.025159 (rank : 14)	θ value	0.47712 (rank : 7)
Query Neighborhood Hits	22	Target Neighborhood Hits	56	Shared Neighborhood Hits	2
SwissProt Accessions	Q86XS5, Q86VR9	Gene names	ANGPTL5
Domain Architecture	No domain graphic available
Description	Angiopoietin-related protein 5 precursor (Angiopoietin-like 5).

GDIB_MOUSE
NC score	0.024631 (rank : 15)	θ value	5.27518 (rank : 18)
Query Neighborhood Hits	22	Target Neighborhood Hits	17	Shared Neighborhood Hits	3
SwissProt Accessions	Q61598, Q541Z9, Q8C530, Q9D8M9	Gene names	Gdi2, Gdi3
Domain Architecture
Description	Rab GDP dissociation inhibitor beta (Rab GDI beta) (Guanosine diphosphate dissociation inhibitor 2) (GDI-2) (GDI-3).

RBBP6_MOUSE
NC score	0.017463 (rank : 16)	θ value	3.0926 (rank : 15)
Query Neighborhood Hits	22	Target Neighborhood Hits	1014	Shared Neighborhood Hits	5
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

PER3_HUMAN
NC score	0.016372 (rank : 17)	θ value	3.0926 (rank : 14)
Query Neighborhood Hits	22	Target Neighborhood Hits	479	Shared Neighborhood Hits	2
SwissProt Accessions	P56645, Q5H8X4, Q969K6, Q96S77, Q96S78, Q9C0J3, Q9NSP9, Q9UGU8	Gene names	PER3
Domain Architecture
Description	Period circadian protein 3 (hPER3).

CTR1_MOUSE
NC score	0.010185 (rank : 18)	θ value	6.88961 (rank : 19)
Query Neighborhood Hits	22	Target Neighborhood Hits	36	Shared Neighborhood Hits	2
SwissProt Accessions	Q09143, P30824	Gene names	Slc7a1, Atrc1, Rec-1
Domain Architecture
Description	High-affinity cationic amino acid transporter 1 (CAT-1) (CAT1) (System Y+ basic amino acid transporter) (Ecotropic retroviral leukemia receptor) (ERR) (Ecotropic retrovirus receptor).

CHD9_HUMAN
NC score	0.010055 (rank : 19)	θ value	4.03905 (rank : 16)
Query Neighborhood Hits	22	Target Neighborhood Hits	343	Shared Neighborhood Hits	5
SwissProt Accessions	Q3L8U1, O15025, Q1WF12, Q6DTK9, Q9H9V7	Gene names	CHD9, KIAA0308, KISH2, PRIC320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Chromatin-related mesenchymal modulator) (CReMM) (Chromatin remodeling factor CHROM1) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha-interacting complex protein 320 kDa) (Kismet homolog 2).

NDRG4_MOUSE
NC score	0.009133 (rank : 20)	θ value	8.99809 (rank : 21)
Query Neighborhood Hits	22	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BTG7	Gene names	Ndrg4, Ndr4
Domain Architecture	No domain graphic available
Description	Protein NDRG4 (Protein Ndr4).

KCNV2_HUMAN
NC score	0.004990 (rank : 21)	θ value	8.99809 (rank : 20)
Query Neighborhood Hits	22	Target Neighborhood Hits	137	Shared Neighborhood Hits	2
SwissProt Accessions	Q8TDN2	Gene names	KCNV2
Domain Architecture
Description	Potassium voltage-gated channel subfamily V member 2 (Voltage-gated potassium channel subunit Kv8.2).

TITIN_HUMAN
NC score	0.002740 (rank : 22)	θ value	4.03905 (rank : 17)
Query Neighborhood Hits	22	Target Neighborhood Hits	2923	Shared Neighborhood Hits	6
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

ZN236_HUMAN
NC score	0.000082 (rank : 23)	θ value	8.99809 (rank : 22)
Query Neighborhood Hits	22	Target Neighborhood Hits	844	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UL36, Q9UL37	Gene names	ZNF236
Domain Architecture	No domain graphic available
Description	Zinc finger protein 236.