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Network neighborhood for query Sequence : PSPB_MOUSE

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PSPB_MOUSE
SwissProt Accessions	P50405	Gene names	Sftpb, Sftp3
Domain Architecture
Description	Pulmonary surfactant-associated protein B precursor (SP-B) (Pulmonary surfactant-associated proteolipid SPL(Phe)).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PSPB_MOUSE
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	8	Target Neighborhood Hits	8	Shared Neighborhood Hits	8
SwissProt Accessions	P50405	Gene names	Sftpb, Sftp3
Domain Architecture
Description	Pulmonary surfactant-associated protein B precursor (SP-B) (Pulmonary surfactant-associated proteolipid SPL(Phe)).

PSPB_HUMAN
θ value	1.62758e-142 (rank : 2)	NC score	0.990135 (rank : 2)
Query Neighborhood Hits	8	Target Neighborhood Hits	14	Shared Neighborhood Hits	6
SwissProt Accessions	P07988, Q96R04	Gene names	SFTPB, SFTP3
Domain Architecture
Description	Pulmonary surfactant-associated protein B precursor (SP-B) (6 kDa protein) (Pulmonary surfactant-associated proteolipid SPL(Phe)) (18 kDa pulmonary-surfactant protein).

SAP_HUMAN
θ value	5.79196e-23 (rank : 3)	NC score	0.682714 (rank : 3)
Query Neighborhood Hits	8	Target Neighborhood Hits	26	Shared Neighborhood Hits	5
SwissProt Accessions	P07602, P07292, P15793, P78538, P78541, P78546, P78547, P78558, Q6IBQ6, Q92739, Q92740, Q92741, Q92742	Gene names	PSAP
Domain Architecture
Description	Proactivator polypeptide precursor [Contains: Saposin A (Protein A); Saposin B-Val; Saposin B (Sphingolipid activator protein 1) (SAP-1) (Cerebroside sulfate activator) (CSAct) (Dispersin) (Sulfatide/GM1 activator); Saposin C (Co-beta-glucosidase) (A1 activator) (Glucosylceramidase activator) (Sphingolipid activator protein 2) (SAP-2); Saposin D (Protein C) (Component C)].

SAP_MOUSE
θ value	8.36355e-22 (rank : 4)	NC score	0.671588 (rank : 4)
Query Neighborhood Hits	8	Target Neighborhood Hits	22	Shared Neighborhood Hits	5
SwissProt Accessions	Q61207, Q60861, Q64006, Q64219	Gene names	Psap, Sgp1
Domain Architecture
Description	Sulfated glycoprotein 1 precursor (SGP-1) (Prosaposin).

AOAH_HUMAN
θ value	1.81305 (rank : 5)	NC score	0.096828 (rank : 5)
Query Neighborhood Hits	8	Target Neighborhood Hits	10	Shared Neighborhood Hits	5
SwissProt Accessions	P28039, Q53F13	Gene names	AOAH
Domain Architecture
Description	Acyloxyacyl hydrolase precursor (EC 3.1.1.77) [Contains: Acyloxyacyl hydrolase small subunit; Acyloxyacyl hydrolase large subunit].

NCOR2_HUMAN
θ value	2.36792 (rank : 6)	NC score	0.018712 (rank : 7)
Query Neighborhood Hits	8	Target Neighborhood Hits	870	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

TRI25_HUMAN
θ value	2.36792 (rank : 7)	NC score	0.021339 (rank : 6)
Query Neighborhood Hits	8	Target Neighborhood Hits	472	Shared Neighborhood Hits	3
SwissProt Accessions	Q14258	Gene names	TRIM25, EFP, RNF147, ZNF147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp) (RING finger protein 147).

Hits sorted by NC score

PSPB_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	8	Target Neighborhood Hits	8	Shared Neighborhood Hits	8
SwissProt Accessions	P50405	Gene names	Sftpb, Sftp3
Domain Architecture
Description	Pulmonary surfactant-associated protein B precursor (SP-B) (Pulmonary surfactant-associated proteolipid SPL(Phe)).

PSPB_HUMAN
NC score	0.990135 (rank : 2)	θ value	1.62758e-142 (rank : 2)
Query Neighborhood Hits	8	Target Neighborhood Hits	14	Shared Neighborhood Hits	6
SwissProt Accessions	P07988, Q96R04	Gene names	SFTPB, SFTP3
Domain Architecture
Description	Pulmonary surfactant-associated protein B precursor (SP-B) (6 kDa protein) (Pulmonary surfactant-associated proteolipid SPL(Phe)) (18 kDa pulmonary-surfactant protein).

SAP_HUMAN
NC score	0.682714 (rank : 3)	θ value	5.79196e-23 (rank : 3)
Query Neighborhood Hits	8	Target Neighborhood Hits	26	Shared Neighborhood Hits	5
SwissProt Accessions	P07602, P07292, P15793, P78538, P78541, P78546, P78547, P78558, Q6IBQ6, Q92739, Q92740, Q92741, Q92742	Gene names	PSAP
Domain Architecture
Description	Proactivator polypeptide precursor [Contains: Saposin A (Protein A); Saposin B-Val; Saposin B (Sphingolipid activator protein 1) (SAP-1) (Cerebroside sulfate activator) (CSAct) (Dispersin) (Sulfatide/GM1 activator); Saposin C (Co-beta-glucosidase) (A1 activator) (Glucosylceramidase activator) (Sphingolipid activator protein 2) (SAP-2); Saposin D (Protein C) (Component C)].

SAP_MOUSE
NC score	0.671588 (rank : 4)	θ value	8.36355e-22 (rank : 4)
Query Neighborhood Hits	8	Target Neighborhood Hits	22	Shared Neighborhood Hits	5
SwissProt Accessions	Q61207, Q60861, Q64006, Q64219	Gene names	Psap, Sgp1
Domain Architecture
Description	Sulfated glycoprotein 1 precursor (SGP-1) (Prosaposin).

AOAH_HUMAN
NC score	0.096828 (rank : 5)	θ value	1.81305 (rank : 5)
Query Neighborhood Hits	8	Target Neighborhood Hits	10	Shared Neighborhood Hits	5
SwissProt Accessions	P28039, Q53F13	Gene names	AOAH
Domain Architecture
Description	Acyloxyacyl hydrolase precursor (EC 3.1.1.77) [Contains: Acyloxyacyl hydrolase small subunit; Acyloxyacyl hydrolase large subunit].

TRI25_HUMAN
NC score	0.021339 (rank : 6)	θ value	2.36792 (rank : 7)
Query Neighborhood Hits	8	Target Neighborhood Hits	472	Shared Neighborhood Hits	3
SwissProt Accessions	Q14258	Gene names	TRIM25, EFP, RNF147, ZNF147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp) (RING finger protein 147).

NCOR2_HUMAN
NC score	0.018712 (rank : 7)	θ value	2.36792 (rank : 6)
Query Neighborhood Hits	8	Target Neighborhood Hits	870	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).