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Network neighborhood for query Sequence : SAPS3_MOUSE

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SAPS3_MOUSE
SwissProt Accessions	Q922D4, Q6ZPM9, Q8BTW6, Q9D2X9	Gene names	Saps3, D19Ertd703e, Kiaa1558
Domain Architecture	No domain graphic available
Description	SAPS domain family member 3.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SAPS1_HUMAN
θ value	0 (rank : 1)	NC score	0.820220 (rank : 6)
Query Neighborhood Hits	77	Target Neighborhood Hits	704	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

SAPS1_MOUSE
θ value	0 (rank : 2)	NC score	0.958997 (rank : 5)
Query Neighborhood Hits	77	Target Neighborhood Hits	144	Shared Neighborhood Hits	16
SwissProt Accessions	Q7TSI3, Q80TJ4	Gene names	Saps1, Kiaa1115
Domain Architecture	No domain graphic available
Description	SAPS domain family member 1.

SAPS2_HUMAN
θ value	0 (rank : 3)	NC score	0.972495 (rank : 3)
Query Neighborhood Hits	77	Target Neighborhood Hits	41	Shared Neighborhood Hits	8
SwissProt Accessions	O75170, Q9UGB9	Gene names	SAPS2, KIAA0685
Domain Architecture
Description	SAPS domain family member 2.

SAPS2_MOUSE
θ value	0 (rank : 4)	NC score	0.971248 (rank : 4)
Query Neighborhood Hits	77	Target Neighborhood Hits	47	Shared Neighborhood Hits	8
SwissProt Accessions	Q8R3Q2, Q9CXB7	Gene names	Saps2, Kiaa0685
Domain Architecture
Description	SAPS domain family member 2.

SAPS3_HUMAN
θ value	0 (rank : 5)	NC score	0.992485 (rank : 2)
Query Neighborhood Hits	77	Target Neighborhood Hits	71	Shared Neighborhood Hits	39
SwissProt Accessions	Q5H9R7, Q3B7I1, Q3I4Y0, Q3KR35, Q68CR3, Q7L4R8, Q8N3B2, Q96MB2, Q9H2K5, Q9H2K6, Q9HCL4, Q9NUY3	Gene names	SAPS3, C11orf23, KIAA1558, PP6R3, SAPL
Domain Architecture	No domain graphic available
Description	SAPS domain family member 3 (Sporulation-induced transcript 4- associated protein SAPL) (Protein phosphatase 6 regulatory subunit 3).

SAPS3_MOUSE
θ value	0 (rank : 6)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	77	Target Neighborhood Hits	77	Shared Neighborhood Hits	77
SwissProt Accessions	Q922D4, Q6ZPM9, Q8BTW6, Q9D2X9	Gene names	Saps3, D19Ertd703e, Kiaa1558
Domain Architecture	No domain graphic available
Description	SAPS domain family member 3.

GP112_HUMAN
θ value	0.0113563 (rank : 7)	NC score	0.032669 (rank : 23)
Query Neighborhood Hits	77	Target Neighborhood Hits	441	Shared Neighborhood Hits	15
SwissProt Accessions	Q8IZF6, Q86SM6	Gene names	GPR112
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 112.

ANK2_HUMAN
θ value	0.0330416 (rank : 8)	NC score	0.032412 (rank : 24)
Query Neighborhood Hits	77	Target Neighborhood Hits	1615	Shared Neighborhood Hits	36
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

EP15_HUMAN
θ value	0.0431538 (rank : 9)	NC score	0.026446 (rank : 30)
Query Neighborhood Hits	77	Target Neighborhood Hits	1021	Shared Neighborhood Hits	20
SwissProt Accessions	P42566	Gene names	EPS15, AF1P
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

CN145_HUMAN
θ value	0.125558 (rank : 10)	NC score	0.021750 (rank : 38)
Query Neighborhood Hits	77	Target Neighborhood Hits	1196	Shared Neighborhood Hits	17
SwissProt Accessions	Q6ZU80, Q96ML4	Gene names	C14orf145
Domain Architecture	No domain graphic available
Description	Protein C14orf145.

NOP14_MOUSE
θ value	0.163984 (rank : 11)	NC score	0.035131 (rank : 17)
Query Neighborhood Hits	77	Target Neighborhood Hits	324	Shared Neighborhood Hits	9
SwissProt Accessions	Q8R3N1	Gene names	Nop14
Domain Architecture	No domain graphic available
Description	Probable nucleolar complex protein 14.

MCPH1_MOUSE
θ value	0.21417 (rank : 12)	NC score	0.037141 (rank : 14)
Query Neighborhood Hits	77	Target Neighborhood Hits	116	Shared Neighborhood Hits	4
SwissProt Accessions	Q7TT79, Q8BNI9, Q8C9I7	Gene names	Mcph1
Domain Architecture
Description	Microcephalin.

NFH_MOUSE
θ value	0.21417 (rank : 13)	NC score	0.026821 (rank : 29)
Query Neighborhood Hits	77	Target Neighborhood Hits	2247	Shared Neighborhood Hits	41
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

STAM1_MOUSE
θ value	0.279714 (rank : 14)	NC score	0.025588 (rank : 33)
Query Neighborhood Hits	77	Target Neighborhood Hits	273	Shared Neighborhood Hits	5
SwissProt Accessions	P70297	Gene names	Stam, Stam1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

STAM1_HUMAN
θ value	0.365318 (rank : 15)	NC score	0.025201 (rank : 34)
Query Neighborhood Hits	77	Target Neighborhood Hits	271	Shared Neighborhood Hits	5
SwissProt Accessions	Q92783, Q8N6D9	Gene names	STAM, STAM1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

ATBF1_MOUSE
θ value	0.47712 (rank : 16)	NC score	0.020536 (rank : 41)
Query Neighborhood Hits	77	Target Neighborhood Hits	1841	Shared Neighborhood Hits	30
SwissProt Accessions	Q61329	Gene names	Atbf1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

CK5P2_HUMAN
θ value	0.47712 (rank : 17)	NC score	0.020450 (rank : 42)
Query Neighborhood Hits	77	Target Neighborhood Hits	1433	Shared Neighborhood Hits	21
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

PRG4_HUMAN
θ value	0.47712 (rank : 18)	NC score	0.054048 (rank : 9)
Query Neighborhood Hits	77	Target Neighborhood Hits	764	Shared Neighborhood Hits	26
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

GRIN1_MOUSE
θ value	0.62314 (rank : 19)	NC score	0.048290 (rank : 11)
Query Neighborhood Hits	77	Target Neighborhood Hits	337	Shared Neighborhood Hits	17
SwissProt Accessions	Q3UNH4, Q6PGF9, Q9QZY2	Gene names	Gprin1
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

ANK3_HUMAN
θ value	0.813845 (rank : 20)	NC score	0.018208 (rank : 47)
Query Neighborhood Hits	77	Target Neighborhood Hits	853	Shared Neighborhood Hits	26
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

NACAM_MOUSE
θ value	0.813845 (rank : 21)	NC score	0.051791 (rank : 10)
Query Neighborhood Hits	77	Target Neighborhood Hits	1866	Shared Neighborhood Hits	43
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

AP2A2_HUMAN
θ value	1.38821 (rank : 22)	NC score	0.028995 (rank : 27)
Query Neighborhood Hits	77	Target Neighborhood Hits	39	Shared Neighborhood Hits	5
SwissProt Accessions	O94973, O75403, Q96SI8	Gene names	AP2A2, ADTAB, KIAA0899
Domain Architecture
Description	AP-2 complex subunit alpha-2 (Adapter-related protein complex 2 alpha- 2 subunit) (Alpha-adaptin C) (Adaptor protein complex AP-2 alpha-2 subunit) (Clathrin assembly protein complex 2 alpha-C large chain) (100 kDa coated vesicle protein C) (Plasma membrane adaptor HA2/AP2 adaptin alpha C subunit) (Huntingtin-interacting protein HYPJ).

AP2A2_MOUSE
θ value	1.38821 (rank : 23)	NC score	0.029237 (rank : 26)
Query Neighborhood Hits	77	Target Neighborhood Hits	46	Shared Neighborhood Hits	5
SwissProt Accessions	P17427, Q921V0	Gene names	Ap2a2, Adtab
Domain Architecture
Description	AP-2 complex subunit alpha-2 (Adapter-related protein complex 2 alpha- 2 subunit) (Alpha-adaptin C) (Adaptor protein complex AP-2 alpha-2 subunit) (Clathrin assembly protein complex 2 alpha-C large chain) (100 kDa coated vesicle protein C) (Plasma membrane adaptor HA2/AP2 adaptin alpha C subunit).

NIPA_MOUSE
θ value	1.38821 (rank : 24)	NC score	0.025985 (rank : 31)
Query Neighborhood Hits	77	Target Neighborhood Hits	50	Shared Neighborhood Hits	5
SwissProt Accessions	Q80YV2, Q3TJE6, Q80Z11, Q8BTW5, Q8CI56, Q8R3U7	Gene names	Zc3hc1, Nipa
Domain Architecture	No domain graphic available
Description	Nuclear-interacting partner of ALK (Nuclear-interacting partner of anaplastic lymphoma kinase) (mNIPA) (Zinc finger C3HC-type protein 1).

SIN3B_HUMAN
θ value	1.38821 (rank : 25)	NC score	0.017480 (rank : 48)
Query Neighborhood Hits	77	Target Neighborhood Hits	82	Shared Neighborhood Hits	4
SwissProt Accessions	O75182, Q68GC2, Q6P4B8, Q8TB34, Q9BSC8	Gene names	SIN3B, KIAA0700
Domain Architecture
Description	Paired amphipathic helix protein Sin3b (Transcriptional corepressor Sin3b) (Histone deacetylase complex subunit Sin3b).

CASC3_MOUSE
θ value	1.81305 (rank : 26)	NC score	0.034882 (rank : 19)
Query Neighborhood Hits	77	Target Neighborhood Hits	333	Shared Neighborhood Hits	15
SwissProt Accessions	Q8K3W3, Q8K219, Q99NF0	Gene names	Casc3, Mln51
Domain Architecture	No domain graphic available
Description	Protein CASC3 (Cancer susceptibility candidate gene 3 protein homolog) (Metastatic lymph node protein 51 homolog) (Protein MLN 51 homolog) (Protein barentsz) (Btz).

NF2L2_HUMAN
θ value	1.81305 (rank : 27)	NC score	0.018379 (rank : 46)
Query Neighborhood Hits	77	Target Neighborhood Hits	109	Shared Neighborhood Hits	8
SwissProt Accessions	Q16236, Q96F71	Gene names	NFE2L2, NRF2
Domain Architecture
Description	Nuclear factor erythroid 2-related factor 2 (NF-E2-related factor 2) (NFE2-related factor 2) (Nuclear factor, erythroid derived 2, like 2) (HEBP1).

RAE2_MOUSE
θ value	1.81305 (rank : 28)	NC score	0.024364 (rank : 37)
Query Neighborhood Hits	77	Target Neighborhood Hits	53	Shared Neighborhood Hits	7
SwissProt Accessions	Q9QZD5, Q8CH16	Gene names	Chml, Rep2
Domain Architecture
Description	Rab proteins geranylgeranyltransferase component A 2 (Rab escort protein 2) (REP-2) (Choroideraemia-like protein).

SPTA1_MOUSE
θ value	1.81305 (rank : 29)	NC score	0.014897 (rank : 51)
Query Neighborhood Hits	77	Target Neighborhood Hits	675	Shared Neighborhood Hits	14
SwissProt Accessions	P08032, P97502	Gene names	Spta1, Spna1, Spta
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

TOP2A_MOUSE
θ value	1.81305 (rank : 30)	NC score	0.018432 (rank : 45)
Query Neighborhood Hits	77	Target Neighborhood Hits	101	Shared Neighborhood Hits	8
SwissProt Accessions	Q01320	Gene names	Top2a, Top-2, Top2
Domain Architecture
Description	DNA topoisomerase 2-alpha (EC 5.99.1.3) (DNA topoisomerase II, alpha isozyme).

ADDA_MOUSE
θ value	2.36792 (rank : 31)	NC score	0.027841 (rank : 28)
Query Neighborhood Hits	77	Target Neighborhood Hits	198	Shared Neighborhood Hits	16
SwissProt Accessions	Q9QYC0, Q9JLE3	Gene names	Add1
Domain Architecture
Description	Alpha-adducin (Erythrocyte adducin subunit alpha).

ADDB_MOUSE
θ value	2.36792 (rank : 32)	NC score	0.020772 (rank : 40)
Query Neighborhood Hits	77	Target Neighborhood Hits	574	Shared Neighborhood Hits	21
SwissProt Accessions	Q9QYB8, Q3U0E1, Q80VH9, Q8C1C4, Q9CXE3, Q9JLE5, Q9QYB7	Gene names	Add2
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta) (Add97).

BSN_HUMAN
θ value	2.36792 (rank : 33)	NC score	0.033017 (rank : 22)
Query Neighborhood Hits	77	Target Neighborhood Hits	1537	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

MDC1_HUMAN
θ value	2.36792 (rank : 34)	NC score	0.042691 (rank : 12)
Query Neighborhood Hits	77	Target Neighborhood Hits	1446	Shared Neighborhood Hits	39
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

MYST3_HUMAN
θ value	2.36792 (rank : 35)	NC score	0.021017 (rank : 39)
Query Neighborhood Hits	77	Target Neighborhood Hits	772	Shared Neighborhood Hits	24
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

RIOK1_HUMAN
θ value	2.36792 (rank : 36)	NC score	0.033781 (rank : 20)
Query Neighborhood Hits	77	Target Neighborhood Hits	86	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BRS2, Q8NDC8, Q96NV9	Gene names	RIOK1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase RIO1 (EC 2.7.11.1) (RIO kinase 1).

SUHW4_MOUSE
θ value	2.36792 (rank : 37)	NC score	0.004692 (rank : 74)
Query Neighborhood Hits	77	Target Neighborhood Hits	737	Shared Neighborhood Hits	7
SwissProt Accessions	Q68FE8, Q3T9B1, Q8BI82	Gene names	Suhw4
Domain Architecture	No domain graphic available
Description	Suppressor of hairy wing homolog 4.

TP53B_HUMAN
θ value	2.36792 (rank : 38)	NC score	0.030215 (rank : 25)
Query Neighborhood Hits	77	Target Neighborhood Hits	413	Shared Neighborhood Hits	19
SwissProt Accessions	Q12888, Q2M1Z7, Q4LE46, Q5FWZ3, Q7Z3U4	Gene names	TP53BP1
Domain Architecture
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

TP53B_MOUSE
θ value	2.36792 (rank : 39)	NC score	0.056558 (rank : 8)
Query Neighborhood Hits	77	Target Neighborhood Hits	644	Shared Neighborhood Hits	31
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

ANR26_HUMAN
θ value	3.0926 (rank : 40)	NC score	0.007708 (rank : 72)
Query Neighborhood Hits	77	Target Neighborhood Hits	1614	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

BSN_MOUSE
θ value	3.0926 (rank : 41)	NC score	0.035084 (rank : 18)
Query Neighborhood Hits	77	Target Neighborhood Hits	2057	Shared Neighborhood Hits	31
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

GP1BA_HUMAN
θ value	3.0926 (rank : 42)	NC score	0.012373 (rank : 58)
Query Neighborhood Hits	77	Target Neighborhood Hits	407	Shared Neighborhood Hits	9
SwissProt Accessions	P07359, Q14441, Q16469, Q8N1F3, Q8NG39, Q9HDC7, Q9UEK1, Q9UQS4	Gene names	GP1BA
Domain Architecture
Description	Platelet glycoprotein Ib alpha chain precursor (Glycoprotein Ibalpha) (GP-Ib alpha) (GPIbA) (GPIb-alpha) (Antigen CD42b-alpha) (CD42b antigen) [Contains: Glycocalicin].

MLL3_MOUSE
θ value	3.0926 (rank : 43)	NC score	0.016275 (rank : 49)
Query Neighborhood Hits	77	Target Neighborhood Hits	1399	Shared Neighborhood Hits	29
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

MYBPH_MOUSE
θ value	3.0926 (rank : 44)	NC score	0.012881 (rank : 56)
Query Neighborhood Hits	77	Target Neighborhood Hits	290	Shared Neighborhood Hits	9
SwissProt Accessions	P70402	Gene names	Mybph
Domain Architecture
Description	Myosin-binding protein H (MyBP-H) (H-protein).

SYTL1_MOUSE
θ value	3.0926 (rank : 45)	NC score	0.009153 (rank : 66)
Query Neighborhood Hits	77	Target Neighborhood Hits	314	Shared Neighborhood Hits	11
SwissProt Accessions	Q99N80, Q99J26	Gene names	Sytl1, Slp1
Domain Architecture
Description	Synaptotagmin-like protein 1 (Exophilin-7).

HDAC5_HUMAN
θ value	4.03905 (rank : 46)	NC score	0.014037 (rank : 54)
Query Neighborhood Hits	77	Target Neighborhood Hits	353	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UQL6, O60340, O60528, Q96DY4	Gene names	HDAC5, KIAA0600
Domain Architecture
Description	Histone deacetylase 5 (HD5) (Antigen NY-CO-9).

LEO1_MOUSE
θ value	4.03905 (rank : 47)	NC score	0.025620 (rank : 32)
Query Neighborhood Hits	77	Target Neighborhood Hits	946	Shared Neighborhood Hits	28
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

SRRM2_HUMAN
θ value	4.03905 (rank : 48)	NC score	0.037623 (rank : 13)
Query Neighborhood Hits	77	Target Neighborhood Hits	1296	Shared Neighborhood Hits	31
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

CCNB3_HUMAN
θ value	5.27518 (rank : 49)	NC score	0.011773 (rank : 60)
Query Neighborhood Hits	77	Target Neighborhood Hits	368	Shared Neighborhood Hits	9
SwissProt Accessions	Q8WWL7, Q96SB5, Q96SB6, Q96SB7, Q9NT38	Gene names	CCNB3, CYCB3
Domain Architecture
Description	G2/mitotic-specific cyclin-B3.

GTPB2_HUMAN
θ value	5.27518 (rank : 50)	NC score	0.024678 (rank : 36)
Query Neighborhood Hits	77	Target Neighborhood Hits	29	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BX10, Q5T7E8, Q8ND84, Q8TAH7, Q8WUA5, Q9HCS9, Q9NRU4, Q9NX60	Gene names	GTPBP2
Domain Architecture	No domain graphic available
Description	GTP-binding protein 2.

GTPB2_MOUSE
θ value	5.27518 (rank : 51)	NC score	0.024684 (rank : 35)
Query Neighborhood Hits	77	Target Neighborhood Hits	28	Shared Neighborhood Hits	4
SwissProt Accessions	Q3UJK4, Q9EST7, Q9JIX7	Gene names	Gtpbp2
Domain Architecture	No domain graphic available
Description	GTP-binding protein 2 (GTP-binding-like protein 2).

JHD2C_MOUSE
θ value	5.27518 (rank : 52)	NC score	0.018609 (rank : 44)
Query Neighborhood Hits	77	Target Neighborhood Hits	297	Shared Neighborhood Hits	18
SwissProt Accessions	Q69ZK6, Q6NV48, Q8BUF5, Q8C4I5, Q8C5Q9	Gene names	Jmjd1c, Jhdm2c, Kiaa1380
Domain Architecture	No domain graphic available
Description	Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C).

OSBP1_HUMAN
θ value	5.27518 (rank : 53)	NC score	0.013793 (rank : 55)
Query Neighborhood Hits	77	Target Neighborhood Hits	180	Shared Neighborhood Hits	3
SwissProt Accessions	P22059	Gene names	OSBP, OSBP1
Domain Architecture
Description	Oxysterol-binding protein 1.

RUSC1_MOUSE
θ value	5.27518 (rank : 54)	NC score	0.012120 (rank : 59)
Query Neighborhood Hits	77	Target Neighborhood Hits	206	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BG26, Q6PHT9	Gene names	Rusc1
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 1.

UBQL4_HUMAN
θ value	5.27518 (rank : 55)	NC score	0.015784 (rank : 50)
Query Neighborhood Hits	77	Target Neighborhood Hits	117	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NRR5, Q9BR98, Q9UHX4	Gene names	UBQLN4, C1orf6, UBIN
Domain Architecture
Description	Ubiquilin-4 (Ataxin-1 ubiquitin-like-interacting protein A1U).

AFF1_HUMAN
θ value	6.88961 (rank : 56)	NC score	0.033693 (rank : 21)
Query Neighborhood Hits	77	Target Neighborhood Hits	506	Shared Neighborhood Hits	26
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

CNTN6_HUMAN
θ value	6.88961 (rank : 57)	NC score	0.003244 (rank : 77)
Query Neighborhood Hits	77	Target Neighborhood Hits	422	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UQ52	Gene names	CNTN6
Domain Architecture	No domain graphic available
Description	Contactin-6 precursor (Neural recognition molecule NB-3) (hNB-3).

CNTN6_MOUSE
θ value	6.88961 (rank : 58)	NC score	0.003175 (rank : 78)
Query Neighborhood Hits	77	Target Neighborhood Hits	429	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JMB8, Q8C6X1	Gene names	Cntn6
Domain Architecture	No domain graphic available
Description	Contactin-6 precursor (Neural recognition molecule NB-3) (mNB-3).

DNL1_MOUSE
θ value	6.88961 (rank : 59)	NC score	0.014534 (rank : 53)
Query Neighborhood Hits	77	Target Neighborhood Hits	110	Shared Neighborhood Hits	8
SwissProt Accessions	P37913	Gene names	Lig1, Lig-1
Domain Architecture
Description	DNA ligase 1 (EC 6.5.1.1) (DNA ligase I) (Polydeoxyribonucleotide synthase [ATP] 1).

HDAC5_MOUSE
θ value	6.88961 (rank : 60)	NC score	0.012770 (rank : 57)
Query Neighborhood Hits	77	Target Neighborhood Hits	310	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Z2V6, Q9JL73	Gene names	Hdac5
Domain Architecture
Description	Histone deacetylase 5 (HD5) (Histone deacetylase mHDA1).

LHX2_HUMAN
θ value	6.88961 (rank : 61)	NC score	0.003247 (rank : 76)
Query Neighborhood Hits	77	Target Neighborhood Hits	432	Shared Neighborhood Hits	3
SwissProt Accessions	P50458, O95860, Q8N1Z3	Gene names	LHX2, LH2
Domain Architecture
Description	LIM/homeobox protein Lhx2 (Homeobox protein LH-2).

MUC2_HUMAN
θ value	6.88961 (rank : 62)	NC score	0.036837 (rank : 15)
Query Neighborhood Hits	77	Target Neighborhood Hits	906	Shared Neighborhood Hits	23
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

SPTB2_HUMAN
θ value	6.88961 (rank : 63)	NC score	0.008124 (rank : 70)
Query Neighborhood Hits	77	Target Neighborhood Hits	748	Shared Neighborhood Hits	13
SwissProt Accessions	Q01082, O60837, Q16057	Gene names	SPTBN1, SPTB2
Domain Architecture
Description	Spectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1) (Beta-II spectrin) (Fodrin beta chain).

SPTB2_MOUSE
θ value	6.88961 (rank : 64)	NC score	0.007934 (rank : 71)
Query Neighborhood Hits	77	Target Neighborhood Hits	770	Shared Neighborhood Hits	15
SwissProt Accessions	Q62261, Q5SQL8	Gene names	Sptbn1, Spnb-2, Spnb2, Sptb2
Domain Architecture
Description	Spectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1) (Beta-II spectrin) (Fodrin beta chain).

SRRM2_MOUSE
θ value	6.88961 (rank : 65)	NC score	0.035601 (rank : 16)
Query Neighborhood Hits	77	Target Neighborhood Hits	1470	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

WDR7_HUMAN
θ value	6.88961 (rank : 66)	NC score	0.011435 (rank : 63)
Query Neighborhood Hits	77	Target Neighborhood Hits	244	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y4E6, Q86UX5, Q86VP2, Q96PS7	Gene names	WDR7, KIAA0541, TRAG
Domain Architecture	No domain graphic available
Description	WD repeat protein 7 (TGF-beta resistance-associated protein TRAG) (Rabconnectin-3 beta).

E41L3_MOUSE
θ value	8.99809 (rank : 67)	NC score	0.006142 (rank : 73)
Query Neighborhood Hits	77	Target Neighborhood Hits	250	Shared Neighborhood Hits	10
SwissProt Accessions	Q9WV92, Q9R102	Gene names	Epb41l3, Dal1, Epb4.1l3
Domain Architecture
Description	Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1) (DAL1P) (mDAL-1).

EDD1_HUMAN
θ value	8.99809 (rank : 68)	NC score	0.011722 (rank : 61)
Query Neighborhood Hits	77	Target Neighborhood Hits	170	Shared Neighborhood Hits	7
SwissProt Accessions	O95071, O94970, Q9NPL3	Gene names	EDD1, EDD, HYD, KIAA0896
Domain Architecture
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog) (hHYD) (Progestin-induced protein).

HCN3_MOUSE
θ value	8.99809 (rank : 69)	NC score	0.003702 (rank : 75)
Query Neighborhood Hits	77	Target Neighborhood Hits	112	Shared Neighborhood Hits	3
SwissProt Accessions	O88705	Gene names	Hcn3, Hac3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 (Hyperpolarization-activated cation channel 3) (HAC-3).

LEO1_HUMAN
θ value	8.99809 (rank : 70)	NC score	0.014586 (rank : 52)
Query Neighborhood Hits	77	Target Neighborhood Hits	958	Shared Neighborhood Hits	25
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

LPIN2_HUMAN
θ value	8.99809 (rank : 71)	NC score	0.011653 (rank : 62)
Query Neighborhood Hits	77	Target Neighborhood Hits	117	Shared Neighborhood Hits	9
SwissProt Accessions	Q92539	Gene names	LPIN2, KIAA0249
Domain Architecture	No domain graphic available
Description	Lipin-2.

NCOR1_HUMAN
θ value	8.99809 (rank : 72)	NC score	0.010109 (rank : 65)
Query Neighborhood Hits	77	Target Neighborhood Hits	577	Shared Neighborhood Hits	24
SwissProt Accessions	O75376, Q9UPV5, Q9UQ18	Gene names	NCOR1, KIAA1047
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR).

NOP56_HUMAN
θ value	8.99809 (rank : 73)	NC score	0.008406 (rank : 68)
Query Neighborhood Hits	77	Target Neighborhood Hits	95	Shared Neighborhood Hits	4
SwissProt Accessions	O00567, Q9NQ05	Gene names	NOL5A, NOP56
Domain Architecture
Description	Nucleolar protein Nop56 (Nucleolar protein 5A).

NP1L3_MOUSE
θ value	8.99809 (rank : 74)	NC score	0.011232 (rank : 64)
Query Neighborhood Hits	77	Target Neighborhood Hits	233	Shared Neighborhood Hits	15
SwissProt Accessions	Q794H2, O54802	Gene names	Nap1l3, Mb20
Domain Architecture	No domain graphic available
Description	Nucleosome assembly protein 1-like 3 (Brain-specific protein MB20).

PVRL2_MOUSE
θ value	8.99809 (rank : 75)	NC score	0.008654 (rank : 67)
Query Neighborhood Hits	77	Target Neighborhood Hits	242	Shared Neighborhood Hits	4
SwissProt Accessions	P32507, Q62096	Gene names	Pvrl2, Mph, Pvr, Pvs
Domain Architecture
Description	Poliovirus receptor-related protein 2 precursor (Murine herpesvirus entry protein B) (mHveB) (Nectin-2) (Poliovirus receptor homolog) (CD112 antigen).

R3HD1_HUMAN
θ value	8.99809 (rank : 76)	NC score	0.018918 (rank : 43)
Query Neighborhood Hits	77	Target Neighborhood Hits	203	Shared Neighborhood Hits	10
SwissProt Accessions	Q15032, Q8IW32	Gene names	R3HDM1, KIAA0029, R3HDM
Domain Architecture	No domain graphic available
Description	R3H domain-containing protein 1.

T240L_MOUSE
θ value	8.99809 (rank : 77)	NC score	0.008280 (rank : 69)
Query Neighborhood Hits	77	Target Neighborhood Hits	143	Shared Neighborhood Hits	7
SwissProt Accessions	Q6JPI3, Q3TRF4, Q3UQI8, Q80TM3, Q80WQ0	Gene names	Thrap2, Kiaa1025, Trap240l
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 2 (Thyroid hormone receptor-associated protein complex 240 kDa component-like).

MUC7_HUMAN
θ value	θ > 10 (rank : 78)	NC score	0.068615 (rank : 7)
Query Neighborhood Hits	77	Target Neighborhood Hits	538	Shared Neighborhood Hits	20
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

Hits sorted by NC score

SAPS3_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 6)
Query Neighborhood Hits	77	Target Neighborhood Hits	77	Shared Neighborhood Hits	77
SwissProt Accessions	Q922D4, Q6ZPM9, Q8BTW6, Q9D2X9	Gene names	Saps3, D19Ertd703e, Kiaa1558
Domain Architecture	No domain graphic available
Description	SAPS domain family member 3.

SAPS3_HUMAN
NC score	0.992485 (rank : 2)	θ value	0 (rank : 5)
Query Neighborhood Hits	77	Target Neighborhood Hits	71	Shared Neighborhood Hits	39
SwissProt Accessions	Q5H9R7, Q3B7I1, Q3I4Y0, Q3KR35, Q68CR3, Q7L4R8, Q8N3B2, Q96MB2, Q9H2K5, Q9H2K6, Q9HCL4, Q9NUY3	Gene names	SAPS3, C11orf23, KIAA1558, PP6R3, SAPL
Domain Architecture	No domain graphic available
Description	SAPS domain family member 3 (Sporulation-induced transcript 4- associated protein SAPL) (Protein phosphatase 6 regulatory subunit 3).

SAPS2_HUMAN
NC score	0.972495 (rank : 3)	θ value	0 (rank : 3)
Query Neighborhood Hits	77	Target Neighborhood Hits	41	Shared Neighborhood Hits	8
SwissProt Accessions	O75170, Q9UGB9	Gene names	SAPS2, KIAA0685
Domain Architecture
Description	SAPS domain family member 2.

SAPS2_MOUSE
NC score	0.971248 (rank : 4)	θ value	0 (rank : 4)
Query Neighborhood Hits	77	Target Neighborhood Hits	47	Shared Neighborhood Hits	8
SwissProt Accessions	Q8R3Q2, Q9CXB7	Gene names	Saps2, Kiaa0685
Domain Architecture
Description	SAPS domain family member 2.

SAPS1_MOUSE
NC score	0.958997 (rank : 5)	θ value	0 (rank : 2)
Query Neighborhood Hits	77	Target Neighborhood Hits	144	Shared Neighborhood Hits	16
SwissProt Accessions	Q7TSI3, Q80TJ4	Gene names	Saps1, Kiaa1115
Domain Architecture	No domain graphic available
Description	SAPS domain family member 1.

SAPS1_HUMAN
NC score	0.820220 (rank : 6)	θ value	0 (rank : 1)
Query Neighborhood Hits	77	Target Neighborhood Hits	704	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

MUC7_HUMAN
NC score	0.068615 (rank : 7)	θ value	θ > 10 (rank : 78)
Query Neighborhood Hits	77	Target Neighborhood Hits	538	Shared Neighborhood Hits	20
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

TP53B_MOUSE
NC score	0.056558 (rank : 8)	θ value	2.36792 (rank : 39)
Query Neighborhood Hits	77	Target Neighborhood Hits	644	Shared Neighborhood Hits	31
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

PRG4_HUMAN
NC score	0.054048 (rank : 9)	θ value	0.47712 (rank : 18)
Query Neighborhood Hits	77	Target Neighborhood Hits	764	Shared Neighborhood Hits	26
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

NACAM_MOUSE
NC score	0.051791 (rank : 10)	θ value	0.813845 (rank : 21)
Query Neighborhood Hits	77	Target Neighborhood Hits	1866	Shared Neighborhood Hits	43
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

GRIN1_MOUSE
NC score	0.048290 (rank : 11)	θ value	0.62314 (rank : 19)
Query Neighborhood Hits	77	Target Neighborhood Hits	337	Shared Neighborhood Hits	17
SwissProt Accessions	Q3UNH4, Q6PGF9, Q9QZY2	Gene names	Gprin1
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

MDC1_HUMAN
NC score	0.042691 (rank : 12)	θ value	2.36792 (rank : 34)
Query Neighborhood Hits	77	Target Neighborhood Hits	1446	Shared Neighborhood Hits	39
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

SRRM2_HUMAN
NC score	0.037623 (rank : 13)	θ value	4.03905 (rank : 48)
Query Neighborhood Hits	77	Target Neighborhood Hits	1296	Shared Neighborhood Hits	31
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

MCPH1_MOUSE
NC score	0.037141 (rank : 14)	θ value	0.21417 (rank : 12)
Query Neighborhood Hits	77	Target Neighborhood Hits	116	Shared Neighborhood Hits	4
SwissProt Accessions	Q7TT79, Q8BNI9, Q8C9I7	Gene names	Mcph1
Domain Architecture
Description	Microcephalin.

MUC2_HUMAN
NC score	0.036837 (rank : 15)	θ value	6.88961 (rank : 62)
Query Neighborhood Hits	77	Target Neighborhood Hits	906	Shared Neighborhood Hits	23
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

SRRM2_MOUSE
NC score	0.035601 (rank : 16)	θ value	6.88961 (rank : 65)
Query Neighborhood Hits	77	Target Neighborhood Hits	1470	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

NOP14_MOUSE
NC score	0.035131 (rank : 17)	θ value	0.163984 (rank : 11)
Query Neighborhood Hits	77	Target Neighborhood Hits	324	Shared Neighborhood Hits	9
SwissProt Accessions	Q8R3N1	Gene names	Nop14
Domain Architecture	No domain graphic available
Description	Probable nucleolar complex protein 14.

BSN_MOUSE
NC score	0.035084 (rank : 18)	θ value	3.0926 (rank : 41)
Query Neighborhood Hits	77	Target Neighborhood Hits	2057	Shared Neighborhood Hits	31
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

CASC3_MOUSE
NC score	0.034882 (rank : 19)	θ value	1.81305 (rank : 26)
Query Neighborhood Hits	77	Target Neighborhood Hits	333	Shared Neighborhood Hits	15
SwissProt Accessions	Q8K3W3, Q8K219, Q99NF0	Gene names	Casc3, Mln51
Domain Architecture	No domain graphic available
Description	Protein CASC3 (Cancer susceptibility candidate gene 3 protein homolog) (Metastatic lymph node protein 51 homolog) (Protein MLN 51 homolog) (Protein barentsz) (Btz).

RIOK1_HUMAN
NC score	0.033781 (rank : 20)	θ value	2.36792 (rank : 36)
Query Neighborhood Hits	77	Target Neighborhood Hits	86	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BRS2, Q8NDC8, Q96NV9	Gene names	RIOK1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase RIO1 (EC 2.7.11.1) (RIO kinase 1).

AFF1_HUMAN
NC score	0.033693 (rank : 21)	θ value	6.88961 (rank : 56)
Query Neighborhood Hits	77	Target Neighborhood Hits	506	Shared Neighborhood Hits	26
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

BSN_HUMAN
NC score	0.033017 (rank : 22)	θ value	2.36792 (rank : 33)
Query Neighborhood Hits	77	Target Neighborhood Hits	1537	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

GP112_HUMAN
NC score	0.032669 (rank : 23)	θ value	0.0113563 (rank : 7)
Query Neighborhood Hits	77	Target Neighborhood Hits	441	Shared Neighborhood Hits	15
SwissProt Accessions	Q8IZF6, Q86SM6	Gene names	GPR112
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 112.

ANK2_HUMAN
NC score	0.032412 (rank : 24)	θ value	0.0330416 (rank : 8)
Query Neighborhood Hits	77	Target Neighborhood Hits	1615	Shared Neighborhood Hits	36
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

TP53B_HUMAN
NC score	0.030215 (rank : 25)	θ value	2.36792 (rank : 38)
Query Neighborhood Hits	77	Target Neighborhood Hits	413	Shared Neighborhood Hits	19
SwissProt Accessions	Q12888, Q2M1Z7, Q4LE46, Q5FWZ3, Q7Z3U4	Gene names	TP53BP1
Domain Architecture
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

AP2A2_MOUSE
NC score	0.029237 (rank : 26)	θ value	1.38821 (rank : 23)
Query Neighborhood Hits	77	Target Neighborhood Hits	46	Shared Neighborhood Hits	5
SwissProt Accessions	P17427, Q921V0	Gene names	Ap2a2, Adtab
Domain Architecture
Description	AP-2 complex subunit alpha-2 (Adapter-related protein complex 2 alpha- 2 subunit) (Alpha-adaptin C) (Adaptor protein complex AP-2 alpha-2 subunit) (Clathrin assembly protein complex 2 alpha-C large chain) (100 kDa coated vesicle protein C) (Plasma membrane adaptor HA2/AP2 adaptin alpha C subunit).

AP2A2_HUMAN
NC score	0.028995 (rank : 27)	θ value	1.38821 (rank : 22)
Query Neighborhood Hits	77	Target Neighborhood Hits	39	Shared Neighborhood Hits	5
SwissProt Accessions	O94973, O75403, Q96SI8	Gene names	AP2A2, ADTAB, KIAA0899
Domain Architecture
Description	AP-2 complex subunit alpha-2 (Adapter-related protein complex 2 alpha- 2 subunit) (Alpha-adaptin C) (Adaptor protein complex AP-2 alpha-2 subunit) (Clathrin assembly protein complex 2 alpha-C large chain) (100 kDa coated vesicle protein C) (Plasma membrane adaptor HA2/AP2 adaptin alpha C subunit) (Huntingtin-interacting protein HYPJ).

ADDA_MOUSE
NC score	0.027841 (rank : 28)	θ value	2.36792 (rank : 31)
Query Neighborhood Hits	77	Target Neighborhood Hits	198	Shared Neighborhood Hits	16
SwissProt Accessions	Q9QYC0, Q9JLE3	Gene names	Add1
Domain Architecture
Description	Alpha-adducin (Erythrocyte adducin subunit alpha).

NFH_MOUSE
NC score	0.026821 (rank : 29)	θ value	0.21417 (rank : 13)
Query Neighborhood Hits	77	Target Neighborhood Hits	2247	Shared Neighborhood Hits	41
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

EP15_HUMAN
NC score	0.026446 (rank : 30)	θ value	0.0431538 (rank : 9)
Query Neighborhood Hits	77	Target Neighborhood Hits	1021	Shared Neighborhood Hits	20
SwissProt Accessions	P42566	Gene names	EPS15, AF1P
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

NIPA_MOUSE
NC score	0.025985 (rank : 31)	θ value	1.38821 (rank : 24)
Query Neighborhood Hits	77	Target Neighborhood Hits	50	Shared Neighborhood Hits	5
SwissProt Accessions	Q80YV2, Q3TJE6, Q80Z11, Q8BTW5, Q8CI56, Q8R3U7	Gene names	Zc3hc1, Nipa
Domain Architecture	No domain graphic available
Description	Nuclear-interacting partner of ALK (Nuclear-interacting partner of anaplastic lymphoma kinase) (mNIPA) (Zinc finger C3HC-type protein 1).

LEO1_MOUSE
NC score	0.025620 (rank : 32)	θ value	4.03905 (rank : 47)
Query Neighborhood Hits	77	Target Neighborhood Hits	946	Shared Neighborhood Hits	28
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

STAM1_MOUSE
NC score	0.025588 (rank : 33)	θ value	0.279714 (rank : 14)
Query Neighborhood Hits	77	Target Neighborhood Hits	273	Shared Neighborhood Hits	5
SwissProt Accessions	P70297	Gene names	Stam, Stam1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

STAM1_HUMAN
NC score	0.025201 (rank : 34)	θ value	0.365318 (rank : 15)
Query Neighborhood Hits	77	Target Neighborhood Hits	271	Shared Neighborhood Hits	5
SwissProt Accessions	Q92783, Q8N6D9	Gene names	STAM, STAM1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

GTPB2_MOUSE
NC score	0.024684 (rank : 35)	θ value	5.27518 (rank : 51)
Query Neighborhood Hits	77	Target Neighborhood Hits	28	Shared Neighborhood Hits	4
SwissProt Accessions	Q3UJK4, Q9EST7, Q9JIX7	Gene names	Gtpbp2
Domain Architecture	No domain graphic available
Description	GTP-binding protein 2 (GTP-binding-like protein 2).

GTPB2_HUMAN
NC score	0.024678 (rank : 36)	θ value	5.27518 (rank : 50)
Query Neighborhood Hits	77	Target Neighborhood Hits	29	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BX10, Q5T7E8, Q8ND84, Q8TAH7, Q8WUA5, Q9HCS9, Q9NRU4, Q9NX60	Gene names	GTPBP2
Domain Architecture	No domain graphic available
Description	GTP-binding protein 2.

RAE2_MOUSE
NC score	0.024364 (rank : 37)	θ value	1.81305 (rank : 28)
Query Neighborhood Hits	77	Target Neighborhood Hits	53	Shared Neighborhood Hits	7
SwissProt Accessions	Q9QZD5, Q8CH16	Gene names	Chml, Rep2
Domain Architecture
Description	Rab proteins geranylgeranyltransferase component A 2 (Rab escort protein 2) (REP-2) (Choroideraemia-like protein).

CN145_HUMAN
NC score	0.021750 (rank : 38)	θ value	0.125558 (rank : 10)
Query Neighborhood Hits	77	Target Neighborhood Hits	1196	Shared Neighborhood Hits	17
SwissProt Accessions	Q6ZU80, Q96ML4	Gene names	C14orf145
Domain Architecture	No domain graphic available
Description	Protein C14orf145.

MYST3_HUMAN
NC score	0.021017 (rank : 39)	θ value	2.36792 (rank : 35)
Query Neighborhood Hits	77	Target Neighborhood Hits	772	Shared Neighborhood Hits	24
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

ADDB_MOUSE
NC score	0.020772 (rank : 40)	θ value	2.36792 (rank : 32)
Query Neighborhood Hits	77	Target Neighborhood Hits	574	Shared Neighborhood Hits	21
SwissProt Accessions	Q9QYB8, Q3U0E1, Q80VH9, Q8C1C4, Q9CXE3, Q9JLE5, Q9QYB7	Gene names	Add2
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta) (Add97).

ATBF1_MOUSE
NC score	0.020536 (rank : 41)	θ value	0.47712 (rank : 16)
Query Neighborhood Hits	77	Target Neighborhood Hits	1841	Shared Neighborhood Hits	30
SwissProt Accessions	Q61329	Gene names	Atbf1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

CK5P2_HUMAN
NC score	0.020450 (rank : 42)	θ value	0.47712 (rank : 17)
Query Neighborhood Hits	77	Target Neighborhood Hits	1433	Shared Neighborhood Hits	21
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

R3HD1_HUMAN
NC score	0.018918 (rank : 43)	θ value	8.99809 (rank : 76)
Query Neighborhood Hits	77	Target Neighborhood Hits	203	Shared Neighborhood Hits	10
SwissProt Accessions	Q15032, Q8IW32	Gene names	R3HDM1, KIAA0029, R3HDM
Domain Architecture	No domain graphic available
Description	R3H domain-containing protein 1.

JHD2C_MOUSE
NC score	0.018609 (rank : 44)	θ value	5.27518 (rank : 52)
Query Neighborhood Hits	77	Target Neighborhood Hits	297	Shared Neighborhood Hits	18
SwissProt Accessions	Q69ZK6, Q6NV48, Q8BUF5, Q8C4I5, Q8C5Q9	Gene names	Jmjd1c, Jhdm2c, Kiaa1380
Domain Architecture	No domain graphic available
Description	Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C).

TOP2A_MOUSE
NC score	0.018432 (rank : 45)	θ value	1.81305 (rank : 30)
Query Neighborhood Hits	77	Target Neighborhood Hits	101	Shared Neighborhood Hits	8
SwissProt Accessions	Q01320	Gene names	Top2a, Top-2, Top2
Domain Architecture
Description	DNA topoisomerase 2-alpha (EC 5.99.1.3) (DNA topoisomerase II, alpha isozyme).

NF2L2_HUMAN
NC score	0.018379 (rank : 46)	θ value	1.81305 (rank : 27)
Query Neighborhood Hits	77	Target Neighborhood Hits	109	Shared Neighborhood Hits	8
SwissProt Accessions	Q16236, Q96F71	Gene names	NFE2L2, NRF2
Domain Architecture
Description	Nuclear factor erythroid 2-related factor 2 (NF-E2-related factor 2) (NFE2-related factor 2) (Nuclear factor, erythroid derived 2, like 2) (HEBP1).

ANK3_HUMAN
NC score	0.018208 (rank : 47)	θ value	0.813845 (rank : 20)
Query Neighborhood Hits	77	Target Neighborhood Hits	853	Shared Neighborhood Hits	26
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

SIN3B_HUMAN
NC score	0.017480 (rank : 48)	θ value	1.38821 (rank : 25)
Query Neighborhood Hits	77	Target Neighborhood Hits	82	Shared Neighborhood Hits	4
SwissProt Accessions	O75182, Q68GC2, Q6P4B8, Q8TB34, Q9BSC8	Gene names	SIN3B, KIAA0700
Domain Architecture
Description	Paired amphipathic helix protein Sin3b (Transcriptional corepressor Sin3b) (Histone deacetylase complex subunit Sin3b).

MLL3_MOUSE
NC score	0.016275 (rank : 49)	θ value	3.0926 (rank : 43)
Query Neighborhood Hits	77	Target Neighborhood Hits	1399	Shared Neighborhood Hits	29
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

UBQL4_HUMAN
NC score	0.015784 (rank : 50)	θ value	5.27518 (rank : 55)
Query Neighborhood Hits	77	Target Neighborhood Hits	117	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NRR5, Q9BR98, Q9UHX4	Gene names	UBQLN4, C1orf6, UBIN
Domain Architecture
Description	Ubiquilin-4 (Ataxin-1 ubiquitin-like-interacting protein A1U).

SPTA1_MOUSE
NC score	0.014897 (rank : 51)	θ value	1.81305 (rank : 29)
Query Neighborhood Hits	77	Target Neighborhood Hits	675	Shared Neighborhood Hits	14
SwissProt Accessions	P08032, P97502	Gene names	Spta1, Spna1, Spta
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

LEO1_HUMAN
NC score	0.014586 (rank : 52)	θ value	8.99809 (rank : 70)
Query Neighborhood Hits	77	Target Neighborhood Hits	958	Shared Neighborhood Hits	25
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

DNL1_MOUSE
NC score	0.014534 (rank : 53)	θ value	6.88961 (rank : 59)
Query Neighborhood Hits	77	Target Neighborhood Hits	110	Shared Neighborhood Hits	8
SwissProt Accessions	P37913	Gene names	Lig1, Lig-1
Domain Architecture
Description	DNA ligase 1 (EC 6.5.1.1) (DNA ligase I) (Polydeoxyribonucleotide synthase [ATP] 1).

HDAC5_HUMAN
NC score	0.014037 (rank : 54)	θ value	4.03905 (rank : 46)
Query Neighborhood Hits	77	Target Neighborhood Hits	353	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UQL6, O60340, O60528, Q96DY4	Gene names	HDAC5, KIAA0600
Domain Architecture
Description	Histone deacetylase 5 (HD5) (Antigen NY-CO-9).

OSBP1_HUMAN
NC score	0.013793 (rank : 55)	θ value	5.27518 (rank : 53)
Query Neighborhood Hits	77	Target Neighborhood Hits	180	Shared Neighborhood Hits	3
SwissProt Accessions	P22059	Gene names	OSBP, OSBP1
Domain Architecture
Description	Oxysterol-binding protein 1.

MYBPH_MOUSE
NC score	0.012881 (rank : 56)	θ value	3.0926 (rank : 44)
Query Neighborhood Hits	77	Target Neighborhood Hits	290	Shared Neighborhood Hits	9
SwissProt Accessions	P70402	Gene names	Mybph
Domain Architecture
Description	Myosin-binding protein H (MyBP-H) (H-protein).

HDAC5_MOUSE
NC score	0.012770 (rank : 57)	θ value	6.88961 (rank : 60)
Query Neighborhood Hits	77	Target Neighborhood Hits	310	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Z2V6, Q9JL73	Gene names	Hdac5
Domain Architecture
Description	Histone deacetylase 5 (HD5) (Histone deacetylase mHDA1).

GP1BA_HUMAN
NC score	0.012373 (rank : 58)	θ value	3.0926 (rank : 42)
Query Neighborhood Hits	77	Target Neighborhood Hits	407	Shared Neighborhood Hits	9
SwissProt Accessions	P07359, Q14441, Q16469, Q8N1F3, Q8NG39, Q9HDC7, Q9UEK1, Q9UQS4	Gene names	GP1BA
Domain Architecture
Description	Platelet glycoprotein Ib alpha chain precursor (Glycoprotein Ibalpha) (GP-Ib alpha) (GPIbA) (GPIb-alpha) (Antigen CD42b-alpha) (CD42b antigen) [Contains: Glycocalicin].

RUSC1_MOUSE
NC score	0.012120 (rank : 59)	θ value	5.27518 (rank : 54)
Query Neighborhood Hits	77	Target Neighborhood Hits	206	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BG26, Q6PHT9	Gene names	Rusc1
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 1.

CCNB3_HUMAN
NC score	0.011773 (rank : 60)	θ value	5.27518 (rank : 49)
Query Neighborhood Hits	77	Target Neighborhood Hits	368	Shared Neighborhood Hits	9
SwissProt Accessions	Q8WWL7, Q96SB5, Q96SB6, Q96SB7, Q9NT38	Gene names	CCNB3, CYCB3
Domain Architecture
Description	G2/mitotic-specific cyclin-B3.

EDD1_HUMAN
NC score	0.011722 (rank : 61)	θ value	8.99809 (rank : 68)
Query Neighborhood Hits	77	Target Neighborhood Hits	170	Shared Neighborhood Hits	7
SwissProt Accessions	O95071, O94970, Q9NPL3	Gene names	EDD1, EDD, HYD, KIAA0896
Domain Architecture
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog) (hHYD) (Progestin-induced protein).

LPIN2_HUMAN
NC score	0.011653 (rank : 62)	θ value	8.99809 (rank : 71)
Query Neighborhood Hits	77	Target Neighborhood Hits	117	Shared Neighborhood Hits	9
SwissProt Accessions	Q92539	Gene names	LPIN2, KIAA0249
Domain Architecture	No domain graphic available
Description	Lipin-2.

WDR7_HUMAN
NC score	0.011435 (rank : 63)	θ value	6.88961 (rank : 66)
Query Neighborhood Hits	77	Target Neighborhood Hits	244	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y4E6, Q86UX5, Q86VP2, Q96PS7	Gene names	WDR7, KIAA0541, TRAG
Domain Architecture	No domain graphic available
Description	WD repeat protein 7 (TGF-beta resistance-associated protein TRAG) (Rabconnectin-3 beta).

NP1L3_MOUSE
NC score	0.011232 (rank : 64)	θ value	8.99809 (rank : 74)
Query Neighborhood Hits	77	Target Neighborhood Hits	233	Shared Neighborhood Hits	15
SwissProt Accessions	Q794H2, O54802	Gene names	Nap1l3, Mb20
Domain Architecture	No domain graphic available
Description	Nucleosome assembly protein 1-like 3 (Brain-specific protein MB20).

NCOR1_HUMAN
NC score	0.010109 (rank : 65)	θ value	8.99809 (rank : 72)
Query Neighborhood Hits	77	Target Neighborhood Hits	577	Shared Neighborhood Hits	24
SwissProt Accessions	O75376, Q9UPV5, Q9UQ18	Gene names	NCOR1, KIAA1047
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR).

SYTL1_MOUSE
NC score	0.009153 (rank : 66)	θ value	3.0926 (rank : 45)
Query Neighborhood Hits	77	Target Neighborhood Hits	314	Shared Neighborhood Hits	11
SwissProt Accessions	Q99N80, Q99J26	Gene names	Sytl1, Slp1
Domain Architecture
Description	Synaptotagmin-like protein 1 (Exophilin-7).

PVRL2_MOUSE
NC score	0.008654 (rank : 67)	θ value	8.99809 (rank : 75)
Query Neighborhood Hits	77	Target Neighborhood Hits	242	Shared Neighborhood Hits	4
SwissProt Accessions	P32507, Q62096	Gene names	Pvrl2, Mph, Pvr, Pvs
Domain Architecture
Description	Poliovirus receptor-related protein 2 precursor (Murine herpesvirus entry protein B) (mHveB) (Nectin-2) (Poliovirus receptor homolog) (CD112 antigen).

NOP56_HUMAN
NC score	0.008406 (rank : 68)	θ value	8.99809 (rank : 73)
Query Neighborhood Hits	77	Target Neighborhood Hits	95	Shared Neighborhood Hits	4
SwissProt Accessions	O00567, Q9NQ05	Gene names	NOL5A, NOP56
Domain Architecture
Description	Nucleolar protein Nop56 (Nucleolar protein 5A).

T240L_MOUSE
NC score	0.008280 (rank : 69)	θ value	8.99809 (rank : 77)
Query Neighborhood Hits	77	Target Neighborhood Hits	143	Shared Neighborhood Hits	7
SwissProt Accessions	Q6JPI3, Q3TRF4, Q3UQI8, Q80TM3, Q80WQ0	Gene names	Thrap2, Kiaa1025, Trap240l
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 2 (Thyroid hormone receptor-associated protein complex 240 kDa component-like).

SPTB2_HUMAN
NC score	0.008124 (rank : 70)	θ value	6.88961 (rank : 63)
Query Neighborhood Hits	77	Target Neighborhood Hits	748	Shared Neighborhood Hits	13
SwissProt Accessions	Q01082, O60837, Q16057	Gene names	SPTBN1, SPTB2
Domain Architecture
Description	Spectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1) (Beta-II spectrin) (Fodrin beta chain).

SPTB2_MOUSE
NC score	0.007934 (rank : 71)	θ value	6.88961 (rank : 64)
Query Neighborhood Hits	77	Target Neighborhood Hits	770	Shared Neighborhood Hits	15
SwissProt Accessions	Q62261, Q5SQL8	Gene names	Sptbn1, Spnb-2, Spnb2, Sptb2
Domain Architecture
Description	Spectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1) (Beta-II spectrin) (Fodrin beta chain).

ANR26_HUMAN
NC score	0.007708 (rank : 72)	θ value	3.0926 (rank : 40)
Query Neighborhood Hits	77	Target Neighborhood Hits	1614	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

E41L3_MOUSE
NC score	0.006142 (rank : 73)	θ value	8.99809 (rank : 67)
Query Neighborhood Hits	77	Target Neighborhood Hits	250	Shared Neighborhood Hits	10
SwissProt Accessions	Q9WV92, Q9R102	Gene names	Epb41l3, Dal1, Epb4.1l3
Domain Architecture
Description	Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1) (DAL1P) (mDAL-1).

SUHW4_MOUSE
NC score	0.004692 (rank : 74)	θ value	2.36792 (rank : 37)
Query Neighborhood Hits	77	Target Neighborhood Hits	737	Shared Neighborhood Hits	7
SwissProt Accessions	Q68FE8, Q3T9B1, Q8BI82	Gene names	Suhw4
Domain Architecture	No domain graphic available
Description	Suppressor of hairy wing homolog 4.

HCN3_MOUSE
NC score	0.003702 (rank : 75)	θ value	8.99809 (rank : 69)
Query Neighborhood Hits	77	Target Neighborhood Hits	112	Shared Neighborhood Hits	3
SwissProt Accessions	O88705	Gene names	Hcn3, Hac3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 (Hyperpolarization-activated cation channel 3) (HAC-3).

LHX2_HUMAN
NC score	0.003247 (rank : 76)	θ value	6.88961 (rank : 61)
Query Neighborhood Hits	77	Target Neighborhood Hits	432	Shared Neighborhood Hits	3
SwissProt Accessions	P50458, O95860, Q8N1Z3	Gene names	LHX2, LH2
Domain Architecture
Description	LIM/homeobox protein Lhx2 (Homeobox protein LH-2).

CNTN6_HUMAN
NC score	0.003244 (rank : 77)	θ value	6.88961 (rank : 57)
Query Neighborhood Hits	77	Target Neighborhood Hits	422	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UQ52	Gene names	CNTN6
Domain Architecture	No domain graphic available
Description	Contactin-6 precursor (Neural recognition molecule NB-3) (hNB-3).

CNTN6_MOUSE
NC score	0.003175 (rank : 78)	θ value	6.88961 (rank : 58)
Query Neighborhood Hits	77	Target Neighborhood Hits	429	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JMB8, Q8C6X1	Gene names	Cntn6
Domain Architecture	No domain graphic available
Description	Contactin-6 precursor (Neural recognition molecule NB-3) (mNB-3).