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Network neighborhood for query Sequence : SAPS3_HUMAN

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SAPS3_HUMAN
SwissProt Accessions	Q5H9R7, Q3B7I1, Q3I4Y0, Q3KR35, Q68CR3, Q7L4R8, Q8N3B2, Q96MB2, Q9H2K5, Q9H2K6, Q9HCL4, Q9NUY3	Gene names	SAPS3, C11orf23, KIAA1558, PP6R3, SAPL
Domain Architecture	No domain graphic available
Description	SAPS domain family member 3 (Sporulation-induced transcript 4- associated protein SAPL) (Protein phosphatase 6 regulatory subunit 3).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SAPS1_HUMAN
θ value	0 (rank : 1)	NC score	0.819263 (rank : 6)
Query Neighborhood Hits	71	Target Neighborhood Hits	704	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

SAPS1_MOUSE
θ value	0 (rank : 2)	NC score	0.960233 (rank : 5)
Query Neighborhood Hits	71	Target Neighborhood Hits	144	Shared Neighborhood Hits	13
SwissProt Accessions	Q7TSI3, Q80TJ4	Gene names	Saps1, Kiaa1115
Domain Architecture	No domain graphic available
Description	SAPS domain family member 1.

SAPS2_HUMAN
θ value	0 (rank : 3)	NC score	0.972266 (rank : 3)
Query Neighborhood Hits	71	Target Neighborhood Hits	41	Shared Neighborhood Hits	7
SwissProt Accessions	O75170, Q9UGB9	Gene names	SAPS2, KIAA0685
Domain Architecture
Description	SAPS domain family member 2.

SAPS2_MOUSE
θ value	0 (rank : 4)	NC score	0.971178 (rank : 4)
Query Neighborhood Hits	71	Target Neighborhood Hits	47	Shared Neighborhood Hits	7
SwissProt Accessions	Q8R3Q2, Q9CXB7	Gene names	Saps2, Kiaa0685
Domain Architecture
Description	SAPS domain family member 2.

SAPS3_HUMAN
θ value	0 (rank : 5)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	71	Target Neighborhood Hits	71	Shared Neighborhood Hits	71
SwissProt Accessions	Q5H9R7, Q3B7I1, Q3I4Y0, Q3KR35, Q68CR3, Q7L4R8, Q8N3B2, Q96MB2, Q9H2K5, Q9H2K6, Q9HCL4, Q9NUY3	Gene names	SAPS3, C11orf23, KIAA1558, PP6R3, SAPL
Domain Architecture	No domain graphic available
Description	SAPS domain family member 3 (Sporulation-induced transcript 4- associated protein SAPL) (Protein phosphatase 6 regulatory subunit 3).

SAPS3_MOUSE
θ value	0 (rank : 6)	NC score	0.992485 (rank : 2)
Query Neighborhood Hits	71	Target Neighborhood Hits	77	Shared Neighborhood Hits	39
SwissProt Accessions	Q922D4, Q6ZPM9, Q8BTW6, Q9D2X9	Gene names	Saps3, D19Ertd703e, Kiaa1558
Domain Architecture	No domain graphic available
Description	SAPS domain family member 3.

ANK2_HUMAN
θ value	0.0252991 (rank : 7)	NC score	0.030518 (rank : 21)
Query Neighborhood Hits	71	Target Neighborhood Hits	1615	Shared Neighborhood Hits	31
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

CN145_HUMAN
θ value	0.0736092 (rank : 8)	NC score	0.020034 (rank : 33)
Query Neighborhood Hits	71	Target Neighborhood Hits	1196	Shared Neighborhood Hits	15
SwissProt Accessions	Q6ZU80, Q96ML4	Gene names	C14orf145
Domain Architecture	No domain graphic available
Description	Protein C14orf145.

MLL3_HUMAN
θ value	0.0961366 (rank : 9)	NC score	0.026980 (rank : 22)
Query Neighborhood Hits	71	Target Neighborhood Hits	1644	Shared Neighborhood Hits	32
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

AP2A2_HUMAN
θ value	0.365318 (rank : 10)	NC score	0.034334 (rank : 15)
Query Neighborhood Hits	71	Target Neighborhood Hits	39	Shared Neighborhood Hits	4
SwissProt Accessions	O94973, O75403, Q96SI8	Gene names	AP2A2, ADTAB, KIAA0899
Domain Architecture
Description	AP-2 complex subunit alpha-2 (Adapter-related protein complex 2 alpha- 2 subunit) (Alpha-adaptin C) (Adaptor protein complex AP-2 alpha-2 subunit) (Clathrin assembly protein complex 2 alpha-C large chain) (100 kDa coated vesicle protein C) (Plasma membrane adaptor HA2/AP2 adaptin alpha C subunit) (Huntingtin-interacting protein HYPJ).

AP2A2_MOUSE
θ value	0.365318 (rank : 11)	NC score	0.034594 (rank : 14)
Query Neighborhood Hits	71	Target Neighborhood Hits	46	Shared Neighborhood Hits	5
SwissProt Accessions	P17427, Q921V0	Gene names	Ap2a2, Adtab
Domain Architecture
Description	AP-2 complex subunit alpha-2 (Adapter-related protein complex 2 alpha- 2 subunit) (Alpha-adaptin C) (Adaptor protein complex AP-2 alpha-2 subunit) (Clathrin assembly protein complex 2 alpha-C large chain) (100 kDa coated vesicle protein C) (Plasma membrane adaptor HA2/AP2 adaptin alpha C subunit).

CK5P2_HUMAN
θ value	0.365318 (rank : 12)	NC score	0.019244 (rank : 36)
Query Neighborhood Hits	71	Target Neighborhood Hits	1433	Shared Neighborhood Hits	18
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

CN092_HUMAN
θ value	0.365318 (rank : 13)	NC score	0.031124 (rank : 20)
Query Neighborhood Hits	71	Target Neighborhood Hits	143	Shared Neighborhood Hits	6
SwissProt Accessions	O94842	Gene names	C14orf92, KIAA0737
Domain Architecture
Description	Epidermal Langerhans cell protein LCP1.

GRIN1_MOUSE
θ value	0.365318 (rank : 14)	NC score	0.046897 (rank : 9)
Query Neighborhood Hits	71	Target Neighborhood Hits	337	Shared Neighborhood Hits	16
SwissProt Accessions	Q3UNH4, Q6PGF9, Q9QZY2	Gene names	Gprin1
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

HIC2_HUMAN
θ value	0.47712 (rank : 15)	NC score	0.002535 (rank : 70)
Query Neighborhood Hits	71	Target Neighborhood Hits	820	Shared Neighborhood Hits	5
SwissProt Accessions	Q96JB3, Q96KR3, Q9NSM9, Q9UPX9	Gene names	HIC2, HRG22, KIAA1020, ZBTB30
Domain Architecture
Description	Hypermethylated in cancer 2 protein (Hic-2) (Hic-3) (HIC1-related gene on chromosome 22) (Zinc finger and BTB domain-containing protein 30).

NFH_MOUSE
θ value	0.47712 (rank : 16)	NC score	0.024540 (rank : 27)
Query Neighborhood Hits	71	Target Neighborhood Hits	2247	Shared Neighborhood Hits	40
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

OSBP1_HUMAN
θ value	0.813845 (rank : 17)	NC score	0.017544 (rank : 40)
Query Neighborhood Hits	71	Target Neighborhood Hits	180	Shared Neighborhood Hits	3
SwissProt Accessions	P22059	Gene names	OSBP, OSBP1
Domain Architecture
Description	Oxysterol-binding protein 1.

PTN13_HUMAN
θ value	0.813845 (rank : 18)	NC score	0.008781 (rank : 62)
Query Neighborhood Hits	71	Target Neighborhood Hits	471	Shared Neighborhood Hits	9
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

CGRE1_HUMAN
θ value	1.06291 (rank : 19)	NC score	0.024718 (rank : 26)
Query Neighborhood Hits	71	Target Neighborhood Hits	354	Shared Neighborhood Hits	9
SwissProt Accessions	Q99674	Gene names	CGREF1, CGR11
Domain Architecture	No domain graphic available
Description	Cell growth regulator with EF hand domain 1 (Cell growth regulatory gene 11 protein).

GTPB2_HUMAN
θ value	1.06291 (rank : 20)	NC score	0.033329 (rank : 18)
Query Neighborhood Hits	71	Target Neighborhood Hits	29	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BX10, Q5T7E8, Q8ND84, Q8TAH7, Q8WUA5, Q9HCS9, Q9NRU4, Q9NX60	Gene names	GTPBP2
Domain Architecture	No domain graphic available
Description	GTP-binding protein 2.

GTPB2_MOUSE
θ value	1.06291 (rank : 21)	NC score	0.033337 (rank : 17)
Query Neighborhood Hits	71	Target Neighborhood Hits	28	Shared Neighborhood Hits	4
SwissProt Accessions	Q3UJK4, Q9EST7, Q9JIX7	Gene names	Gtpbp2
Domain Architecture	No domain graphic available
Description	GTP-binding protein 2 (GTP-binding-like protein 2).

MYST3_HUMAN
θ value	1.06291 (rank : 22)	NC score	0.023273 (rank : 29)
Query Neighborhood Hits	71	Target Neighborhood Hits	772	Shared Neighborhood Hits	21
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

NF2L2_MOUSE
θ value	1.06291 (rank : 23)	NC score	0.019540 (rank : 35)
Query Neighborhood Hits	71	Target Neighborhood Hits	183	Shared Neighborhood Hits	5
SwissProt Accessions	Q60795	Gene names	Nfe2l2, Nrf-2, Nrf2
Domain Architecture
Description	Nuclear factor erythroid 2-related factor 2 (NF-E2-related factor 2) (NFE2-related factor 2) (Nuclear factor, erythroid derived 2, like 2).

MDC1_HUMAN
θ value	1.38821 (rank : 24)	NC score	0.035887 (rank : 13)
Query Neighborhood Hits	71	Target Neighborhood Hits	1446	Shared Neighborhood Hits	30
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

RAE2_MOUSE
θ value	1.38821 (rank : 25)	NC score	0.024963 (rank : 25)
Query Neighborhood Hits	71	Target Neighborhood Hits	53	Shared Neighborhood Hits	6
SwissProt Accessions	Q9QZD5, Q8CH16	Gene names	Chml, Rep2
Domain Architecture
Description	Rab proteins geranylgeranyltransferase component A 2 (Rab escort protein 2) (REP-2) (Choroideraemia-like protein).

RIOK1_HUMAN
θ value	1.38821 (rank : 26)	NC score	0.035894 (rank : 12)
Query Neighborhood Hits	71	Target Neighborhood Hits	86	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BRS2, Q8NDC8, Q96NV9	Gene names	RIOK1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase RIO1 (EC 2.7.11.1) (RIO kinase 1).

TP53B_MOUSE
θ value	1.38821 (rank : 27)	NC score	0.047029 (rank : 8)
Query Neighborhood Hits	71	Target Neighborhood Hits	644	Shared Neighborhood Hits	25
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

ZN598_HUMAN
θ value	1.38821 (rank : 28)	NC score	0.024298 (rank : 28)
Query Neighborhood Hits	71	Target Neighborhood Hits	339	Shared Neighborhood Hits	6
SwissProt Accessions	Q86UK7, Q8IW49, Q8N3D9, Q96FG3, Q9H7J3	Gene names	ZNF598
Domain Architecture	No domain graphic available
Description	Zinc finger protein 598.

CASC3_MOUSE
θ value	1.81305 (rank : 29)	NC score	0.033006 (rank : 19)
Query Neighborhood Hits	71	Target Neighborhood Hits	333	Shared Neighborhood Hits	11
SwissProt Accessions	Q8K3W3, Q8K219, Q99NF0	Gene names	Casc3, Mln51
Domain Architecture	No domain graphic available
Description	Protein CASC3 (Cancer susceptibility candidate gene 3 protein homolog) (Metastatic lymph node protein 51 homolog) (Protein MLN 51 homolog) (Protein barentsz) (Btz).

EP15_HUMAN
θ value	1.81305 (rank : 30)	NC score	0.020337 (rank : 32)
Query Neighborhood Hits	71	Target Neighborhood Hits	1021	Shared Neighborhood Hits	15
SwissProt Accessions	P42566	Gene names	EPS15, AF1P
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

TSH1_HUMAN
θ value	1.81305 (rank : 31)	NC score	0.012916 (rank : 52)
Query Neighborhood Hits	71	Target Neighborhood Hits	558	Shared Neighborhood Hits	9
SwissProt Accessions	Q6ZSZ6, O60534, Q4LE29, Q53EU4	Gene names	TSHZ1, SDCCAG33, TSH1
Domain Architecture	No domain graphic available
Description	Teashirt homolog 1 (Serologically defined colon cancer antigen 3) (Antigen NY-CO-33).

ANK3_HUMAN
θ value	2.36792 (rank : 32)	NC score	0.016741 (rank : 42)
Query Neighborhood Hits	71	Target Neighborhood Hits	853	Shared Neighborhood Hits	19
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

SHAN1_HUMAN
θ value	2.36792 (rank : 33)	NC score	0.019732 (rank : 34)
Query Neighborhood Hits	71	Target Neighborhood Hits	1041	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

SYN1_HUMAN
θ value	2.36792 (rank : 34)	NC score	0.033854 (rank : 16)
Query Neighborhood Hits	71	Target Neighborhood Hits	419	Shared Neighborhood Hits	14
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

TAU_HUMAN
θ value	2.36792 (rank : 35)	NC score	0.025786 (rank : 24)
Query Neighborhood Hits	71	Target Neighborhood Hits	448	Shared Neighborhood Hits	15
SwissProt Accessions	P10636, P18518, Q14799, Q15549, Q15550, Q15551, Q9UDJ3, Q9UMH0, Q9UQ96	Gene names	MAPT, MTBT1, TAU
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

UBQL4_HUMAN
θ value	2.36792 (rank : 36)	NC score	0.016956 (rank : 41)
Query Neighborhood Hits	71	Target Neighborhood Hits	117	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NRR5, Q9BR98, Q9UHX4	Gene names	UBQLN4, C1orf6, UBIN
Domain Architecture
Description	Ubiquilin-4 (Ataxin-1 ubiquitin-like-interacting protein A1U).

CLMN_MOUSE
θ value	3.0926 (rank : 37)	NC score	0.009457 (rank : 60)
Query Neighborhood Hits	71	Target Neighborhood Hits	180	Shared Neighborhood Hits	8
SwissProt Accessions	Q8C5W0, Q91V71, Q91XT7, Q91XT8, Q91XU9	Gene names	Clmn
Domain Architecture
Description	Calmin.

GP1BA_HUMAN
θ value	3.0926 (rank : 38)	NC score	0.012134 (rank : 53)
Query Neighborhood Hits	71	Target Neighborhood Hits	407	Shared Neighborhood Hits	9
SwissProt Accessions	P07359, Q14441, Q16469, Q8N1F3, Q8NG39, Q9HDC7, Q9UEK1, Q9UQS4	Gene names	GP1BA
Domain Architecture
Description	Platelet glycoprotein Ib alpha chain precursor (Glycoprotein Ibalpha) (GP-Ib alpha) (GPIbA) (GPIb-alpha) (Antigen CD42b-alpha) (CD42b antigen) [Contains: Glycocalicin].

LEO1_MOUSE
θ value	3.0926 (rank : 39)	NC score	0.026086 (rank : 23)
Query Neighborhood Hits	71	Target Neighborhood Hits	946	Shared Neighborhood Hits	26
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

LPIN2_HUMAN
θ value	3.0926 (rank : 40)	NC score	0.014108 (rank : 48)
Query Neighborhood Hits	71	Target Neighborhood Hits	117	Shared Neighborhood Hits	6
SwissProt Accessions	Q92539	Gene names	LPIN2, KIAA0249
Domain Architecture	No domain graphic available
Description	Lipin-2.

CEBPZ_HUMAN
θ value	4.03905 (rank : 41)	NC score	0.016704 (rank : 43)
Query Neighborhood Hits	71	Target Neighborhood Hits	87	Shared Neighborhood Hits	7
SwissProt Accessions	Q03701, Q8NE75	Gene names	CEBPZ, CBF2
Domain Architecture
Description	CCAAT/enhancer-binding protein zeta (CCAAT-box-binding transcription factor) (CCAAT-binding factor) (CBF).

NCOR1_MOUSE
θ value	4.03905 (rank : 42)	NC score	0.016453 (rank : 44)
Query Neighborhood Hits	71	Target Neighborhood Hits	521	Shared Neighborhood Hits	24
SwissProt Accessions	Q60974, Q60812	Gene names	Ncor1, Rxrip13
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR) (Retinoid X receptor- interacting protein 13) (RIP13).

NEB2_HUMAN
θ value	4.03905 (rank : 43)	NC score	0.013419 (rank : 50)
Query Neighborhood Hits	71	Target Neighborhood Hits	883	Shared Neighborhood Hits	13
SwissProt Accessions	Q96SB3, Q8TCR9	Gene names	PPP1R9B
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

NEB2_MOUSE
θ value	4.03905 (rank : 44)	NC score	0.013987 (rank : 49)
Query Neighborhood Hits	71	Target Neighborhood Hits	889	Shared Neighborhood Hits	15
SwissProt Accessions	Q6R891, Q8K0X7	Gene names	Ppp1r9b
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

R3HD1_HUMAN
θ value	4.03905 (rank : 45)	NC score	0.021672 (rank : 31)
Query Neighborhood Hits	71	Target Neighborhood Hits	203	Shared Neighborhood Hits	7
SwissProt Accessions	Q15032, Q8IW32	Gene names	R3HDM1, KIAA0029, R3HDM
Domain Architecture	No domain graphic available
Description	R3H domain-containing protein 1.

CHD4_HUMAN
θ value	5.27518 (rank : 46)	NC score	0.009940 (rank : 59)
Query Neighborhood Hits	71	Target Neighborhood Hits	365	Shared Neighborhood Hits	13
SwissProt Accessions	Q14839, Q8IXZ5	Gene names	CHD4
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-) (ATP- dependent helicase CHD4) (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta).

CHD4_MOUSE
θ value	5.27518 (rank : 47)	NC score	0.010796 (rank : 57)
Query Neighborhood Hits	71	Target Neighborhood Hits	408	Shared Neighborhood Hits	15
SwissProt Accessions	Q6PDQ2	Gene names	Chd4
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 4 (CHD-4).

CN092_MOUSE
θ value	5.27518 (rank : 48)	NC score	0.022842 (rank : 30)
Query Neighborhood Hits	71	Target Neighborhood Hits	206	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BU11, Q80UI2, Q99PN9, Q9CS16	Gene names
Domain Architecture
Description	Epidermal Langerhans cell protein LCP1.

COX1_MOUSE
θ value	5.27518 (rank : 49)	NC score	0.018839 (rank : 37)
Query Neighborhood Hits	71	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	P00397	Gene names	Mtco1, COI, mt-Co1
Domain Architecture
Description	Cytochrome c oxidase subunit 1 (EC 1.9.3.1) (Cytochrome c oxidase polypeptide I).

GP112_HUMAN
θ value	5.27518 (rank : 50)	NC score	0.018250 (rank : 38)
Query Neighborhood Hits	71	Target Neighborhood Hits	441	Shared Neighborhood Hits	11
SwissProt Accessions	Q8IZF6, Q86SM6	Gene names	GPR112
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 112.

HDAC5_HUMAN
θ value	5.27518 (rank : 51)	NC score	0.013142 (rank : 51)
Query Neighborhood Hits	71	Target Neighborhood Hits	353	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UQL6, O60340, O60528, Q96DY4	Gene names	HDAC5, KIAA0600
Domain Architecture
Description	Histone deacetylase 5 (HD5) (Antigen NY-CO-9).

HIC2_MOUSE
θ value	5.27518 (rank : 52)	NC score	0.001060 (rank : 71)
Query Neighborhood Hits	71	Target Neighborhood Hits	821	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JLZ6, Q3U030, Q3ULP4, Q5K036, Q8BSZ9, Q8C3T5	Gene names	Hic2, Kiaa1020
Domain Architecture
Description	Hypermethylated in cancer 2 protein (Hic-2).

JHD2C_MOUSE
θ value	5.27518 (rank : 53)	NC score	0.017637 (rank : 39)
Query Neighborhood Hits	71	Target Neighborhood Hits	297	Shared Neighborhood Hits	14
SwissProt Accessions	Q69ZK6, Q6NV48, Q8BUF5, Q8C4I5, Q8C5Q9	Gene names	Jmjd1c, Jhdm2c, Kiaa1380
Domain Architecture	No domain graphic available
Description	Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C).

PRG4_HUMAN
θ value	5.27518 (rank : 54)	NC score	0.044932 (rank : 10)
Query Neighborhood Hits	71	Target Neighborhood Hits	764	Shared Neighborhood Hits	23
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

RAI1_MOUSE
θ value	5.27518 (rank : 55)	NC score	0.015866 (rank : 46)
Query Neighborhood Hits	71	Target Neighborhood Hits	344	Shared Neighborhood Hits	9
SwissProt Accessions	Q61818, Q6ZPH7, Q8CEV1	Gene names	Rai1, Kiaa1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

SPTA1_MOUSE
θ value	5.27518 (rank : 56)	NC score	0.008477 (rank : 65)
Query Neighborhood Hits	71	Target Neighborhood Hits	675	Shared Neighborhood Hits	9
SwissProt Accessions	P08032, P97502	Gene names	Spta1, Spna1, Spta
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

TXLNB_HUMAN
θ value	5.27518 (rank : 57)	NC score	0.009391 (rank : 61)
Query Neighborhood Hits	71	Target Neighborhood Hits	912	Shared Neighborhood Hits	17
SwissProt Accessions	Q8N3L3, Q76L25, Q86T52, Q8N3S2	Gene names	TXLNB, C6orf198, MDP77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77) (hMDP77).

WDR7_HUMAN
θ value	5.27518 (rank : 58)	NC score	0.012072 (rank : 54)
Query Neighborhood Hits	71	Target Neighborhood Hits	244	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y4E6, Q86UX5, Q86VP2, Q96PS7	Gene names	WDR7, KIAA0541, TRAG
Domain Architecture	No domain graphic available
Description	WD repeat protein 7 (TGF-beta resistance-associated protein TRAG) (Rabconnectin-3 beta).

BAZ1B_MOUSE
θ value	6.88961 (rank : 59)	NC score	0.011311 (rank : 56)
Query Neighborhood Hits	71	Target Neighborhood Hits	394	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Z277, Q9CU68	Gene names	Baz1b, Wbscr9
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein homolog) (WBRS9).

GNAS1_MOUSE
θ value	6.88961 (rank : 60)	NC score	0.006517 (rank : 67)
Query Neighborhood Hits	71	Target Neighborhood Hits	651	Shared Neighborhood Hits	15
SwissProt Accessions	Q6R0H7, Q6R0H4, Q6R0H5, Q6R2J5, Q9JJX0, Q9Z1N8	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

LEO1_HUMAN
θ value	6.88961 (rank : 61)	NC score	0.014406 (rank : 47)
Query Neighborhood Hits	71	Target Neighborhood Hits	958	Shared Neighborhood Hits	22
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

OST6_HUMAN
θ value	6.88961 (rank : 62)	NC score	0.004925 (rank : 68)
Query Neighborhood Hits	71	Target Neighborhood Hits	38	Shared Neighborhood Hits	2
SwissProt Accessions	Q96QI5, Q96RX7	Gene names	HS3ST6, HS3ST5
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 6 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 6) (Heparan sulfate 3-O-sulfotransferase 6) (h3-OST-6).

STK39_HUMAN
θ value	6.88961 (rank : 63)	NC score	-0.001598 (rank : 72)
Query Neighborhood Hits	71	Target Neighborhood Hits	882	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UEW8, O14774, Q9UER4	Gene names	STK39, SPAK
Domain Architecture
Description	STE20/SPS1-related proline-alanine-rich protein kinase (EC 2.7.11.1) (Ste-20-related kinase) (Serine/threonine-protein kinase 39) (DCHT).

COX1_HUMAN
θ value	8.99809 (rank : 64)	NC score	0.016335 (rank : 45)
Query Neighborhood Hits	71	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	P00395, Q34770	Gene names	MT-CO1, COI, COXI, MTCO1
Domain Architecture
Description	Cytochrome c oxidase subunit 1 (EC 1.9.3.1) (Cytochrome c oxidase polypeptide I).

E41L3_MOUSE
θ value	8.99809 (rank : 65)	NC score	0.008185 (rank : 66)
Query Neighborhood Hits	71	Target Neighborhood Hits	250	Shared Neighborhood Hits	9
SwissProt Accessions	Q9WV92, Q9R102	Gene names	Epb41l3, Dal1, Epb4.1l3
Domain Architecture
Description	Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1) (DAL1P) (mDAL-1).

EHMT2_MOUSE
θ value	8.99809 (rank : 66)	NC score	0.008680 (rank : 63)
Query Neighborhood Hits	71	Target Neighborhood Hits	750	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

FREA_HUMAN
θ value	8.99809 (rank : 67)	NC score	0.003271 (rank : 69)
Query Neighborhood Hits	71	Target Neighborhood Hits	205	Shared Neighborhood Hits	7
SwissProt Accessions	O43638, Q96D28	Gene names	FKHL18, FREAC10
Domain Architecture	No domain graphic available
Description	Forkhead-related transcription factor 10 (FREAC-10) (Forkhead-like 18 protein).

GAH6_HUMAN
θ value	8.99809 (rank : 68)	NC score	0.010164 (rank : 58)
Query Neighborhood Hits	71	Target Neighborhood Hits	18	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N8A4	Gene names
Domain Architecture	No domain graphic available
Description	HERV-H_22q11.2 provirus ancestral Gag polyprotein (Gag polyprotein).

HDAC5_MOUSE
θ value	8.99809 (rank : 69)	NC score	0.012000 (rank : 55)
Query Neighborhood Hits	71	Target Neighborhood Hits	310	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Z2V6, Q9JL73	Gene names	Hdac5
Domain Architecture
Description	Histone deacetylase 5 (HD5) (Histone deacetylase mHDA1).

PVRL2_MOUSE
θ value	8.99809 (rank : 70)	NC score	0.008563 (rank : 64)
Query Neighborhood Hits	71	Target Neighborhood Hits	242	Shared Neighborhood Hits	4
SwissProt Accessions	P32507, Q62096	Gene names	Pvrl2, Mph, Pvr, Pvs
Domain Architecture
Description	Poliovirus receptor-related protein 2 precursor (Murine herpesvirus entry protein B) (mHveB) (Nectin-2) (Poliovirus receptor homolog) (CD112 antigen).

SELPL_MOUSE
θ value	8.99809 (rank : 71)	NC score	0.039994 (rank : 11)
Query Neighborhood Hits	71	Target Neighborhood Hits	588	Shared Neighborhood Hits	23
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

MUC7_HUMAN
θ value	θ > 10 (rank : 72)	NC score	0.065281 (rank : 7)
Query Neighborhood Hits	71	Target Neighborhood Hits	538	Shared Neighborhood Hits	16
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

Hits sorted by NC score

SAPS3_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 5)
Query Neighborhood Hits	71	Target Neighborhood Hits	71	Shared Neighborhood Hits	71
SwissProt Accessions	Q5H9R7, Q3B7I1, Q3I4Y0, Q3KR35, Q68CR3, Q7L4R8, Q8N3B2, Q96MB2, Q9H2K5, Q9H2K6, Q9HCL4, Q9NUY3	Gene names	SAPS3, C11orf23, KIAA1558, PP6R3, SAPL
Domain Architecture	No domain graphic available
Description	SAPS domain family member 3 (Sporulation-induced transcript 4- associated protein SAPL) (Protein phosphatase 6 regulatory subunit 3).

SAPS3_MOUSE
NC score	0.992485 (rank : 2)	θ value	0 (rank : 6)
Query Neighborhood Hits	71	Target Neighborhood Hits	77	Shared Neighborhood Hits	39
SwissProt Accessions	Q922D4, Q6ZPM9, Q8BTW6, Q9D2X9	Gene names	Saps3, D19Ertd703e, Kiaa1558
Domain Architecture	No domain graphic available
Description	SAPS domain family member 3.

SAPS2_HUMAN
NC score	0.972266 (rank : 3)	θ value	0 (rank : 3)
Query Neighborhood Hits	71	Target Neighborhood Hits	41	Shared Neighborhood Hits	7
SwissProt Accessions	O75170, Q9UGB9	Gene names	SAPS2, KIAA0685
Domain Architecture
Description	SAPS domain family member 2.

SAPS2_MOUSE
NC score	0.971178 (rank : 4)	θ value	0 (rank : 4)
Query Neighborhood Hits	71	Target Neighborhood Hits	47	Shared Neighborhood Hits	7
SwissProt Accessions	Q8R3Q2, Q9CXB7	Gene names	Saps2, Kiaa0685
Domain Architecture
Description	SAPS domain family member 2.

SAPS1_MOUSE
NC score	0.960233 (rank : 5)	θ value	0 (rank : 2)
Query Neighborhood Hits	71	Target Neighborhood Hits	144	Shared Neighborhood Hits	13
SwissProt Accessions	Q7TSI3, Q80TJ4	Gene names	Saps1, Kiaa1115
Domain Architecture	No domain graphic available
Description	SAPS domain family member 1.

SAPS1_HUMAN
NC score	0.819263 (rank : 6)	θ value	0 (rank : 1)
Query Neighborhood Hits	71	Target Neighborhood Hits	704	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

MUC7_HUMAN
NC score	0.065281 (rank : 7)	θ value	θ > 10 (rank : 72)
Query Neighborhood Hits	71	Target Neighborhood Hits	538	Shared Neighborhood Hits	16
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

TP53B_MOUSE
NC score	0.047029 (rank : 8)	θ value	1.38821 (rank : 27)
Query Neighborhood Hits	71	Target Neighborhood Hits	644	Shared Neighborhood Hits	25
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

GRIN1_MOUSE
NC score	0.046897 (rank : 9)	θ value	0.365318 (rank : 14)
Query Neighborhood Hits	71	Target Neighborhood Hits	337	Shared Neighborhood Hits	16
SwissProt Accessions	Q3UNH4, Q6PGF9, Q9QZY2	Gene names	Gprin1
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

PRG4_HUMAN
NC score	0.044932 (rank : 10)	θ value	5.27518 (rank : 54)
Query Neighborhood Hits	71	Target Neighborhood Hits	764	Shared Neighborhood Hits	23
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

SELPL_MOUSE
NC score	0.039994 (rank : 11)	θ value	8.99809 (rank : 71)
Query Neighborhood Hits	71	Target Neighborhood Hits	588	Shared Neighborhood Hits	23
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

RIOK1_HUMAN
NC score	0.035894 (rank : 12)	θ value	1.38821 (rank : 26)
Query Neighborhood Hits	71	Target Neighborhood Hits	86	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BRS2, Q8NDC8, Q96NV9	Gene names	RIOK1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase RIO1 (EC 2.7.11.1) (RIO kinase 1).

MDC1_HUMAN
NC score	0.035887 (rank : 13)	θ value	1.38821 (rank : 24)
Query Neighborhood Hits	71	Target Neighborhood Hits	1446	Shared Neighborhood Hits	30
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

AP2A2_MOUSE
NC score	0.034594 (rank : 14)	θ value	0.365318 (rank : 11)
Query Neighborhood Hits	71	Target Neighborhood Hits	46	Shared Neighborhood Hits	5
SwissProt Accessions	P17427, Q921V0	Gene names	Ap2a2, Adtab
Domain Architecture
Description	AP-2 complex subunit alpha-2 (Adapter-related protein complex 2 alpha- 2 subunit) (Alpha-adaptin C) (Adaptor protein complex AP-2 alpha-2 subunit) (Clathrin assembly protein complex 2 alpha-C large chain) (100 kDa coated vesicle protein C) (Plasma membrane adaptor HA2/AP2 adaptin alpha C subunit).

AP2A2_HUMAN
NC score	0.034334 (rank : 15)	θ value	0.365318 (rank : 10)
Query Neighborhood Hits	71	Target Neighborhood Hits	39	Shared Neighborhood Hits	4
SwissProt Accessions	O94973, O75403, Q96SI8	Gene names	AP2A2, ADTAB, KIAA0899
Domain Architecture
Description	AP-2 complex subunit alpha-2 (Adapter-related protein complex 2 alpha- 2 subunit) (Alpha-adaptin C) (Adaptor protein complex AP-2 alpha-2 subunit) (Clathrin assembly protein complex 2 alpha-C large chain) (100 kDa coated vesicle protein C) (Plasma membrane adaptor HA2/AP2 adaptin alpha C subunit) (Huntingtin-interacting protein HYPJ).

SYN1_HUMAN
NC score	0.033854 (rank : 16)	θ value	2.36792 (rank : 34)
Query Neighborhood Hits	71	Target Neighborhood Hits	419	Shared Neighborhood Hits	14
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

GTPB2_MOUSE
NC score	0.033337 (rank : 17)	θ value	1.06291 (rank : 21)
Query Neighborhood Hits	71	Target Neighborhood Hits	28	Shared Neighborhood Hits	4
SwissProt Accessions	Q3UJK4, Q9EST7, Q9JIX7	Gene names	Gtpbp2
Domain Architecture	No domain graphic available
Description	GTP-binding protein 2 (GTP-binding-like protein 2).

GTPB2_HUMAN
NC score	0.033329 (rank : 18)	θ value	1.06291 (rank : 20)
Query Neighborhood Hits	71	Target Neighborhood Hits	29	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BX10, Q5T7E8, Q8ND84, Q8TAH7, Q8WUA5, Q9HCS9, Q9NRU4, Q9NX60	Gene names	GTPBP2
Domain Architecture	No domain graphic available
Description	GTP-binding protein 2.

CASC3_MOUSE
NC score	0.033006 (rank : 19)	θ value	1.81305 (rank : 29)
Query Neighborhood Hits	71	Target Neighborhood Hits	333	Shared Neighborhood Hits	11
SwissProt Accessions	Q8K3W3, Q8K219, Q99NF0	Gene names	Casc3, Mln51
Domain Architecture	No domain graphic available
Description	Protein CASC3 (Cancer susceptibility candidate gene 3 protein homolog) (Metastatic lymph node protein 51 homolog) (Protein MLN 51 homolog) (Protein barentsz) (Btz).

CN092_HUMAN
NC score	0.031124 (rank : 20)	θ value	0.365318 (rank : 13)
Query Neighborhood Hits	71	Target Neighborhood Hits	143	Shared Neighborhood Hits	6
SwissProt Accessions	O94842	Gene names	C14orf92, KIAA0737
Domain Architecture
Description	Epidermal Langerhans cell protein LCP1.

ANK2_HUMAN
NC score	0.030518 (rank : 21)	θ value	0.0252991 (rank : 7)
Query Neighborhood Hits	71	Target Neighborhood Hits	1615	Shared Neighborhood Hits	31
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

MLL3_HUMAN
NC score	0.026980 (rank : 22)	θ value	0.0961366 (rank : 9)
Query Neighborhood Hits	71	Target Neighborhood Hits	1644	Shared Neighborhood Hits	32
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

LEO1_MOUSE
NC score	0.026086 (rank : 23)	θ value	3.0926 (rank : 39)
Query Neighborhood Hits	71	Target Neighborhood Hits	946	Shared Neighborhood Hits	26
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

TAU_HUMAN
NC score	0.025786 (rank : 24)	θ value	2.36792 (rank : 35)
Query Neighborhood Hits	71	Target Neighborhood Hits	448	Shared Neighborhood Hits	15
SwissProt Accessions	P10636, P18518, Q14799, Q15549, Q15550, Q15551, Q9UDJ3, Q9UMH0, Q9UQ96	Gene names	MAPT, MTBT1, TAU
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

RAE2_MOUSE
NC score	0.024963 (rank : 25)	θ value	1.38821 (rank : 25)
Query Neighborhood Hits	71	Target Neighborhood Hits	53	Shared Neighborhood Hits	6
SwissProt Accessions	Q9QZD5, Q8CH16	Gene names	Chml, Rep2
Domain Architecture
Description	Rab proteins geranylgeranyltransferase component A 2 (Rab escort protein 2) (REP-2) (Choroideraemia-like protein).

CGRE1_HUMAN
NC score	0.024718 (rank : 26)	θ value	1.06291 (rank : 19)
Query Neighborhood Hits	71	Target Neighborhood Hits	354	Shared Neighborhood Hits	9
SwissProt Accessions	Q99674	Gene names	CGREF1, CGR11
Domain Architecture	No domain graphic available
Description	Cell growth regulator with EF hand domain 1 (Cell growth regulatory gene 11 protein).

NFH_MOUSE
NC score	0.024540 (rank : 27)	θ value	0.47712 (rank : 16)
Query Neighborhood Hits	71	Target Neighborhood Hits	2247	Shared Neighborhood Hits	40
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

ZN598_HUMAN
NC score	0.024298 (rank : 28)	θ value	1.38821 (rank : 28)
Query Neighborhood Hits	71	Target Neighborhood Hits	339	Shared Neighborhood Hits	6
SwissProt Accessions	Q86UK7, Q8IW49, Q8N3D9, Q96FG3, Q9H7J3	Gene names	ZNF598
Domain Architecture	No domain graphic available
Description	Zinc finger protein 598.

MYST3_HUMAN
NC score	0.023273 (rank : 29)	θ value	1.06291 (rank : 22)
Query Neighborhood Hits	71	Target Neighborhood Hits	772	Shared Neighborhood Hits	21
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

CN092_MOUSE
NC score	0.022842 (rank : 30)	θ value	5.27518 (rank : 48)
Query Neighborhood Hits	71	Target Neighborhood Hits	206	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BU11, Q80UI2, Q99PN9, Q9CS16	Gene names
Domain Architecture
Description	Epidermal Langerhans cell protein LCP1.

R3HD1_HUMAN
NC score	0.021672 (rank : 31)	θ value	4.03905 (rank : 45)
Query Neighborhood Hits	71	Target Neighborhood Hits	203	Shared Neighborhood Hits	7
SwissProt Accessions	Q15032, Q8IW32	Gene names	R3HDM1, KIAA0029, R3HDM
Domain Architecture	No domain graphic available
Description	R3H domain-containing protein 1.

EP15_HUMAN
NC score	0.020337 (rank : 32)	θ value	1.81305 (rank : 30)
Query Neighborhood Hits	71	Target Neighborhood Hits	1021	Shared Neighborhood Hits	15
SwissProt Accessions	P42566	Gene names	EPS15, AF1P
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

CN145_HUMAN
NC score	0.020034 (rank : 33)	θ value	0.0736092 (rank : 8)
Query Neighborhood Hits	71	Target Neighborhood Hits	1196	Shared Neighborhood Hits	15
SwissProt Accessions	Q6ZU80, Q96ML4	Gene names	C14orf145
Domain Architecture	No domain graphic available
Description	Protein C14orf145.

SHAN1_HUMAN
NC score	0.019732 (rank : 34)	θ value	2.36792 (rank : 33)
Query Neighborhood Hits	71	Target Neighborhood Hits	1041	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

NF2L2_MOUSE
NC score	0.019540 (rank : 35)	θ value	1.06291 (rank : 23)
Query Neighborhood Hits	71	Target Neighborhood Hits	183	Shared Neighborhood Hits	5
SwissProt Accessions	Q60795	Gene names	Nfe2l2, Nrf-2, Nrf2
Domain Architecture
Description	Nuclear factor erythroid 2-related factor 2 (NF-E2-related factor 2) (NFE2-related factor 2) (Nuclear factor, erythroid derived 2, like 2).

CK5P2_HUMAN
NC score	0.019244 (rank : 36)	θ value	0.365318 (rank : 12)
Query Neighborhood Hits	71	Target Neighborhood Hits	1433	Shared Neighborhood Hits	18
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

COX1_MOUSE
NC score	0.018839 (rank : 37)	θ value	5.27518 (rank : 49)
Query Neighborhood Hits	71	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	P00397	Gene names	Mtco1, COI, mt-Co1
Domain Architecture
Description	Cytochrome c oxidase subunit 1 (EC 1.9.3.1) (Cytochrome c oxidase polypeptide I).

GP112_HUMAN
NC score	0.018250 (rank : 38)	θ value	5.27518 (rank : 50)
Query Neighborhood Hits	71	Target Neighborhood Hits	441	Shared Neighborhood Hits	11
SwissProt Accessions	Q8IZF6, Q86SM6	Gene names	GPR112
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 112.

JHD2C_MOUSE
NC score	0.017637 (rank : 39)	θ value	5.27518 (rank : 53)
Query Neighborhood Hits	71	Target Neighborhood Hits	297	Shared Neighborhood Hits	14
SwissProt Accessions	Q69ZK6, Q6NV48, Q8BUF5, Q8C4I5, Q8C5Q9	Gene names	Jmjd1c, Jhdm2c, Kiaa1380
Domain Architecture	No domain graphic available
Description	Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C).

OSBP1_HUMAN
NC score	0.017544 (rank : 40)	θ value	0.813845 (rank : 17)
Query Neighborhood Hits	71	Target Neighborhood Hits	180	Shared Neighborhood Hits	3
SwissProt Accessions	P22059	Gene names	OSBP, OSBP1
Domain Architecture
Description	Oxysterol-binding protein 1.

UBQL4_HUMAN
NC score	0.016956 (rank : 41)	θ value	2.36792 (rank : 36)
Query Neighborhood Hits	71	Target Neighborhood Hits	117	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NRR5, Q9BR98, Q9UHX4	Gene names	UBQLN4, C1orf6, UBIN
Domain Architecture
Description	Ubiquilin-4 (Ataxin-1 ubiquitin-like-interacting protein A1U).

ANK3_HUMAN
NC score	0.016741 (rank : 42)	θ value	2.36792 (rank : 32)
Query Neighborhood Hits	71	Target Neighborhood Hits	853	Shared Neighborhood Hits	19
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

CEBPZ_HUMAN
NC score	0.016704 (rank : 43)	θ value	4.03905 (rank : 41)
Query Neighborhood Hits	71	Target Neighborhood Hits	87	Shared Neighborhood Hits	7
SwissProt Accessions	Q03701, Q8NE75	Gene names	CEBPZ, CBF2
Domain Architecture
Description	CCAAT/enhancer-binding protein zeta (CCAAT-box-binding transcription factor) (CCAAT-binding factor) (CBF).

NCOR1_MOUSE
NC score	0.016453 (rank : 44)	θ value	4.03905 (rank : 42)
Query Neighborhood Hits	71	Target Neighborhood Hits	521	Shared Neighborhood Hits	24
SwissProt Accessions	Q60974, Q60812	Gene names	Ncor1, Rxrip13
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR) (Retinoid X receptor- interacting protein 13) (RIP13).

COX1_HUMAN
NC score	0.016335 (rank : 45)	θ value	8.99809 (rank : 64)
Query Neighborhood Hits	71	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	P00395, Q34770	Gene names	MT-CO1, COI, COXI, MTCO1
Domain Architecture
Description	Cytochrome c oxidase subunit 1 (EC 1.9.3.1) (Cytochrome c oxidase polypeptide I).

RAI1_MOUSE
NC score	0.015866 (rank : 46)	θ value	5.27518 (rank : 55)
Query Neighborhood Hits	71	Target Neighborhood Hits	344	Shared Neighborhood Hits	9
SwissProt Accessions	Q61818, Q6ZPH7, Q8CEV1	Gene names	Rai1, Kiaa1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

LEO1_HUMAN
NC score	0.014406 (rank : 47)	θ value	6.88961 (rank : 61)
Query Neighborhood Hits	71	Target Neighborhood Hits	958	Shared Neighborhood Hits	22
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

LPIN2_HUMAN
NC score	0.014108 (rank : 48)	θ value	3.0926 (rank : 40)
Query Neighborhood Hits	71	Target Neighborhood Hits	117	Shared Neighborhood Hits	6
SwissProt Accessions	Q92539	Gene names	LPIN2, KIAA0249
Domain Architecture	No domain graphic available
Description	Lipin-2.

NEB2_MOUSE
NC score	0.013987 (rank : 49)	θ value	4.03905 (rank : 44)
Query Neighborhood Hits	71	Target Neighborhood Hits	889	Shared Neighborhood Hits	15
SwissProt Accessions	Q6R891, Q8K0X7	Gene names	Ppp1r9b
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

NEB2_HUMAN
NC score	0.013419 (rank : 50)	θ value	4.03905 (rank : 43)
Query Neighborhood Hits	71	Target Neighborhood Hits	883	Shared Neighborhood Hits	13
SwissProt Accessions	Q96SB3, Q8TCR9	Gene names	PPP1R9B
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

HDAC5_HUMAN
NC score	0.013142 (rank : 51)	θ value	5.27518 (rank : 51)
Query Neighborhood Hits	71	Target Neighborhood Hits	353	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UQL6, O60340, O60528, Q96DY4	Gene names	HDAC5, KIAA0600
Domain Architecture
Description	Histone deacetylase 5 (HD5) (Antigen NY-CO-9).

TSH1_HUMAN
NC score	0.012916 (rank : 52)	θ value	1.81305 (rank : 31)
Query Neighborhood Hits	71	Target Neighborhood Hits	558	Shared Neighborhood Hits	9
SwissProt Accessions	Q6ZSZ6, O60534, Q4LE29, Q53EU4	Gene names	TSHZ1, SDCCAG33, TSH1
Domain Architecture	No domain graphic available
Description	Teashirt homolog 1 (Serologically defined colon cancer antigen 3) (Antigen NY-CO-33).

GP1BA_HUMAN
NC score	0.012134 (rank : 53)	θ value	3.0926 (rank : 38)
Query Neighborhood Hits	71	Target Neighborhood Hits	407	Shared Neighborhood Hits	9
SwissProt Accessions	P07359, Q14441, Q16469, Q8N1F3, Q8NG39, Q9HDC7, Q9UEK1, Q9UQS4	Gene names	GP1BA
Domain Architecture
Description	Platelet glycoprotein Ib alpha chain precursor (Glycoprotein Ibalpha) (GP-Ib alpha) (GPIbA) (GPIb-alpha) (Antigen CD42b-alpha) (CD42b antigen) [Contains: Glycocalicin].

WDR7_HUMAN
NC score	0.012072 (rank : 54)	θ value	5.27518 (rank : 58)
Query Neighborhood Hits	71	Target Neighborhood Hits	244	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y4E6, Q86UX5, Q86VP2, Q96PS7	Gene names	WDR7, KIAA0541, TRAG
Domain Architecture	No domain graphic available
Description	WD repeat protein 7 (TGF-beta resistance-associated protein TRAG) (Rabconnectin-3 beta).

HDAC5_MOUSE
NC score	0.012000 (rank : 55)	θ value	8.99809 (rank : 69)
Query Neighborhood Hits	71	Target Neighborhood Hits	310	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Z2V6, Q9JL73	Gene names	Hdac5
Domain Architecture
Description	Histone deacetylase 5 (HD5) (Histone deacetylase mHDA1).

BAZ1B_MOUSE
NC score	0.011311 (rank : 56)	θ value	6.88961 (rank : 59)
Query Neighborhood Hits	71	Target Neighborhood Hits	394	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Z277, Q9CU68	Gene names	Baz1b, Wbscr9
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein homolog) (WBRS9).

CHD4_MOUSE
NC score	0.010796 (rank : 57)	θ value	5.27518 (rank : 47)
Query Neighborhood Hits	71	Target Neighborhood Hits	408	Shared Neighborhood Hits	15
SwissProt Accessions	Q6PDQ2	Gene names	Chd4
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 4 (CHD-4).

GAH6_HUMAN
NC score	0.010164 (rank : 58)	θ value	8.99809 (rank : 68)
Query Neighborhood Hits	71	Target Neighborhood Hits	18	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N8A4	Gene names
Domain Architecture	No domain graphic available
Description	HERV-H_22q11.2 provirus ancestral Gag polyprotein (Gag polyprotein).

CHD4_HUMAN
NC score	0.009940 (rank : 59)	θ value	5.27518 (rank : 46)
Query Neighborhood Hits	71	Target Neighborhood Hits	365	Shared Neighborhood Hits	13
SwissProt Accessions	Q14839, Q8IXZ5	Gene names	CHD4
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-) (ATP- dependent helicase CHD4) (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta).

CLMN_MOUSE
NC score	0.009457 (rank : 60)	θ value	3.0926 (rank : 37)
Query Neighborhood Hits	71	Target Neighborhood Hits	180	Shared Neighborhood Hits	8
SwissProt Accessions	Q8C5W0, Q91V71, Q91XT7, Q91XT8, Q91XU9	Gene names	Clmn
Domain Architecture
Description	Calmin.

TXLNB_HUMAN
NC score	0.009391 (rank : 61)	θ value	5.27518 (rank : 57)
Query Neighborhood Hits	71	Target Neighborhood Hits	912	Shared Neighborhood Hits	17
SwissProt Accessions	Q8N3L3, Q76L25, Q86T52, Q8N3S2	Gene names	TXLNB, C6orf198, MDP77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77) (hMDP77).

PTN13_HUMAN
NC score	0.008781 (rank : 62)	θ value	0.813845 (rank : 18)
Query Neighborhood Hits	71	Target Neighborhood Hits	471	Shared Neighborhood Hits	9
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

EHMT2_MOUSE
NC score	0.008680 (rank : 63)	θ value	8.99809 (rank : 66)
Query Neighborhood Hits	71	Target Neighborhood Hits	750	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

PVRL2_MOUSE
NC score	0.008563 (rank : 64)	θ value	8.99809 (rank : 70)
Query Neighborhood Hits	71	Target Neighborhood Hits	242	Shared Neighborhood Hits	4
SwissProt Accessions	P32507, Q62096	Gene names	Pvrl2, Mph, Pvr, Pvs
Domain Architecture
Description	Poliovirus receptor-related protein 2 precursor (Murine herpesvirus entry protein B) (mHveB) (Nectin-2) (Poliovirus receptor homolog) (CD112 antigen).

SPTA1_MOUSE
NC score	0.008477 (rank : 65)	θ value	5.27518 (rank : 56)
Query Neighborhood Hits	71	Target Neighborhood Hits	675	Shared Neighborhood Hits	9
SwissProt Accessions	P08032, P97502	Gene names	Spta1, Spna1, Spta
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

E41L3_MOUSE
NC score	0.008185 (rank : 66)	θ value	8.99809 (rank : 65)
Query Neighborhood Hits	71	Target Neighborhood Hits	250	Shared Neighborhood Hits	9
SwissProt Accessions	Q9WV92, Q9R102	Gene names	Epb41l3, Dal1, Epb4.1l3
Domain Architecture
Description	Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1) (DAL1P) (mDAL-1).

GNAS1_MOUSE
NC score	0.006517 (rank : 67)	θ value	6.88961 (rank : 60)
Query Neighborhood Hits	71	Target Neighborhood Hits	651	Shared Neighborhood Hits	15
SwissProt Accessions	Q6R0H7, Q6R0H4, Q6R0H5, Q6R2J5, Q9JJX0, Q9Z1N8	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

OST6_HUMAN
NC score	0.004925 (rank : 68)	θ value	6.88961 (rank : 62)
Query Neighborhood Hits	71	Target Neighborhood Hits	38	Shared Neighborhood Hits	2
SwissProt Accessions	Q96QI5, Q96RX7	Gene names	HS3ST6, HS3ST5
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 6 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 6) (Heparan sulfate 3-O-sulfotransferase 6) (h3-OST-6).

FREA_HUMAN
NC score	0.003271 (rank : 69)	θ value	8.99809 (rank : 67)
Query Neighborhood Hits	71	Target Neighborhood Hits	205	Shared Neighborhood Hits	7
SwissProt Accessions	O43638, Q96D28	Gene names	FKHL18, FREAC10
Domain Architecture	No domain graphic available
Description	Forkhead-related transcription factor 10 (FREAC-10) (Forkhead-like 18 protein).

HIC2_HUMAN
NC score	0.002535 (rank : 70)	θ value	0.47712 (rank : 15)
Query Neighborhood Hits	71	Target Neighborhood Hits	820	Shared Neighborhood Hits	5
SwissProt Accessions	Q96JB3, Q96KR3, Q9NSM9, Q9UPX9	Gene names	HIC2, HRG22, KIAA1020, ZBTB30
Domain Architecture
Description	Hypermethylated in cancer 2 protein (Hic-2) (Hic-3) (HIC1-related gene on chromosome 22) (Zinc finger and BTB domain-containing protein 30).

HIC2_MOUSE
NC score	0.001060 (rank : 71)	θ value	5.27518 (rank : 52)
Query Neighborhood Hits	71	Target Neighborhood Hits	821	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JLZ6, Q3U030, Q3ULP4, Q5K036, Q8BSZ9, Q8C3T5	Gene names	Hic2, Kiaa1020
Domain Architecture
Description	Hypermethylated in cancer 2 protein (Hic-2).

STK39_HUMAN
NC score	-0.001598 (rank : 72)	θ value	6.88961 (rank : 63)
Query Neighborhood Hits	71	Target Neighborhood Hits	882	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UEW8, O14774, Q9UER4	Gene names	STK39, SPAK
Domain Architecture
Description	STE20/SPS1-related proline-alanine-rich protein kinase (EC 2.7.11.1) (Ste-20-related kinase) (Serine/threonine-protein kinase 39) (DCHT).