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Network neighborhood for query Sequence : RNZ2_HUMAN

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RNZ2_HUMAN
SwissProt Accessions	Q9BQ52, Q9HAS8, Q9HAS9, Q9NVT1	Gene names	ELAC2, HPC2
Domain Architecture
Description	Zinc phosphodiesterase ELAC protein 2 (EC 3.1.26.11) (Ribonuclease Z 2) (RNase Z 2) (tRNase Z 2) (tRNA 3 endonuclease 2) (ElaC homolog protein 2) (Heredity prostate cancer protein 2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

RNZ2_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	17	Target Neighborhood Hits	17	Shared Neighborhood Hits	17
SwissProt Accessions	Q9BQ52, Q9HAS8, Q9HAS9, Q9NVT1	Gene names	ELAC2, HPC2
Domain Architecture
Description	Zinc phosphodiesterase ELAC protein 2 (EC 3.1.26.11) (Ribonuclease Z 2) (RNase Z 2) (tRNase Z 2) (tRNA 3 endonuclease 2) (ElaC homolog protein 2) (Heredity prostate cancer protein 2).

RNZ2_MOUSE
θ value	0 (rank : 2)	NC score	0.990338 (rank : 2)
Query Neighborhood Hits	17	Target Neighborhood Hits	26	Shared Neighborhood Hits	7
SwissProt Accessions	Q80Y81, Q99MF0, Q99MF1, Q9CTA2, Q9D1A8, Q9EPZ2	Gene names	Elac2
Domain Architecture
Description	Zinc phosphodiesterase ELAC protein 2 (EC 3.1.26.11) (Ribonuclease Z 2) (RNase Z 2) (tRNase Z 2) (tRNA 3 endonuclease 2) (ElaC homolog protein 2).

RNZ1_HUMAN
θ value	8.11959e-09 (rank : 3)	NC score	0.396507 (rank : 3)
Query Neighborhood Hits	17	Target Neighborhood Hits	12	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H777, Q9NS99	Gene names	ELAC1, D29
Domain Architecture
Description	Zinc phosphodiesterase ELAC protein 1 (EC 3.1.26.11) (Ribonuclease Z 1) (RNase Z 1) (tRNase Z 1) (tRNA 3 endonuclease 1) (ElaC homolog protein 1) (Deleted in Ma29).

RNZ1_MOUSE
θ value	6.87365e-08 (rank : 4)	NC score	0.379965 (rank : 4)
Query Neighborhood Hits	17	Target Neighborhood Hits	8	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VEB6, Q9CXB1, Q9ERF4	Gene names	Elac1
Domain Architecture
Description	Zinc phosphodiesterase ELAC protein 1 (EC 3.1.26.11) (Ribonuclease Z 1) (RNase Z 1) (tRNase Z 1) (tRNA 3 endonuclease 1) (ElaC homolog protein 1).

TYRO_HUMAN
θ value	0.279714 (rank : 5)	NC score	0.070189 (rank : 5)
Query Neighborhood Hits	17	Target Neighborhood Hits	35	Shared Neighborhood Hits	4
SwissProt Accessions	P14679, Q15675, Q15676, Q15680, Q8TAK4, Q9BYY0, Q9BZX1	Gene names	TYR
Domain Architecture
Description	Tyrosinase precursor (EC 1.14.18.1) (Monophenol monooxygenase) (Tumor rejection antigen AB) (SK29-AB) (LB24-AB).

POF1B_HUMAN
θ value	0.47712 (rank : 6)	NC score	0.030857 (rank : 7)
Query Neighborhood Hits	17	Target Neighborhood Hits	494	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WVV4, Q5H9E9, Q5H9F0, Q8NG12, Q9H5Y2, Q9H738, Q9H744	Gene names	POF1B
Domain Architecture	No domain graphic available
Description	Protein POF1B (Premature ovarian failure protein 1B).

CENPE_HUMAN
θ value	1.81305 (rank : 7)	NC score	0.006113 (rank : 15)
Query Neighborhood Hits	17	Target Neighborhood Hits	2060	Shared Neighborhood Hits	5
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

TITIN_HUMAN
θ value	1.81305 (rank : 8)	NC score	0.004779 (rank : 16)
Query Neighborhood Hits	17	Target Neighborhood Hits	2923	Shared Neighborhood Hits	6
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

TBCD4_HUMAN
θ value	2.36792 (rank : 9)	NC score	0.019035 (rank : 9)
Query Neighborhood Hits	17	Target Neighborhood Hits	357	Shared Neighborhood Hits	4
SwissProt Accessions	O60343, Q5W0B9	Gene names	TBC1D4, KIAA0603
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 4 (Akt substrate of 160 kDa) (AS160).

TYRO_MOUSE
θ value	2.36792 (rank : 10)	NC score	0.051690 (rank : 6)
Query Neighborhood Hits	17	Target Neighborhood Hits	32	Shared Neighborhood Hits	4
SwissProt Accessions	P11344	Gene names	Tyr
Domain Architecture
Description	Tyrosinase precursor (EC 1.14.18.1) (Monophenol monooxygenase) (Albino locus protein).

PCDC1_HUMAN
θ value	4.03905 (rank : 11)	NC score	0.004351 (rank : 17)
Query Neighborhood Hits	17	Target Neighborhood Hits	181	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H158, Q9Y5F5, Q9Y5I5	Gene names	PCDHAC1
Domain Architecture
Description	Protocadherin alpha C1 precursor (PCDH-alpha-C1).

B4GN3_HUMAN
θ value	6.88961 (rank : 12)	NC score	0.012531 (rank : 10)
Query Neighborhood Hits	17	Target Neighborhood Hits	128	Shared Neighborhood Hits	3
SwissProt Accessions	Q6L9W6, Q6ZNC1, Q8N7T6	Gene names	B4GALNT3
Domain Architecture	No domain graphic available
Description	N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N- acetylgalactosaminyltransferase 2 (EC 2.4.1.244) (NGalNAc-T2) (Beta- 1,4-N-acetylgalactosaminyltransferase III) (Beta4GalNAc-T3) (Beta4GalNAcT3).

ETV5_MOUSE
θ value	6.88961 (rank : 13)	NC score	0.020845 (rank : 8)
Query Neighborhood Hits	17	Target Neighborhood Hits	328	Shared Neighborhood Hits	4
SwissProt Accessions	Q9CXC9, Q3TG49, Q8C0F3, Q9JHB1	Gene names	Etv5
Domain Architecture	No domain graphic available
Description	ETS translocation variant 5.

SRRM2_MOUSE
θ value	6.88961 (rank : 14)	NC score	0.007671 (rank : 13)
Query Neighborhood Hits	17	Target Neighborhood Hits	1470	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

JHD3B_HUMAN
θ value	8.99809 (rank : 15)	NC score	0.006734 (rank : 14)
Query Neighborhood Hits	17	Target Neighborhood Hits	128	Shared Neighborhood Hits	2
SwissProt Accessions	O94953, O75274, Q6P3R5, Q9P1V1, Q9UF40	Gene names	JMJD2B, JHDM3B, KIAA0876
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3B (EC 1.14.11.-) (Jumonji domain-containing protein 2B).

PB1_HUMAN
θ value	8.99809 (rank : 16)	NC score	0.010518 (rank : 11)
Query Neighborhood Hits	17	Target Neighborhood Hits	261	Shared Neighborhood Hits	2
SwissProt Accessions	Q86U86, Q9H2T3, Q9H2T4, Q9H2T5, Q9H301, Q9H314	Gene names	PB1
Domain Architecture	No domain graphic available
Description	Protein polybromo-1 (hPB1) (Polybromo-1D) (BRG1-associated factor 180) (BAF180).

RPE65_HUMAN
θ value	8.99809 (rank : 17)	NC score	0.010079 (rank : 12)
Query Neighborhood Hits	17	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	Q16518	Gene names	RPE65
Domain Architecture
Description	Retinal pigment epithelium-specific 65 kDa protein.

Hits sorted by NC score

RNZ2_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	17	Target Neighborhood Hits	17	Shared Neighborhood Hits	17
SwissProt Accessions	Q9BQ52, Q9HAS8, Q9HAS9, Q9NVT1	Gene names	ELAC2, HPC2
Domain Architecture
Description	Zinc phosphodiesterase ELAC protein 2 (EC 3.1.26.11) (Ribonuclease Z 2) (RNase Z 2) (tRNase Z 2) (tRNA 3 endonuclease 2) (ElaC homolog protein 2) (Heredity prostate cancer protein 2).

RNZ2_MOUSE
NC score	0.990338 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	17	Target Neighborhood Hits	26	Shared Neighborhood Hits	7
SwissProt Accessions	Q80Y81, Q99MF0, Q99MF1, Q9CTA2, Q9D1A8, Q9EPZ2	Gene names	Elac2
Domain Architecture
Description	Zinc phosphodiesterase ELAC protein 2 (EC 3.1.26.11) (Ribonuclease Z 2) (RNase Z 2) (tRNase Z 2) (tRNA 3 endonuclease 2) (ElaC homolog protein 2).

RNZ1_HUMAN
NC score	0.396507 (rank : 3)	θ value	8.11959e-09 (rank : 3)
Query Neighborhood Hits	17	Target Neighborhood Hits	12	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H777, Q9NS99	Gene names	ELAC1, D29
Domain Architecture
Description	Zinc phosphodiesterase ELAC protein 1 (EC 3.1.26.11) (Ribonuclease Z 1) (RNase Z 1) (tRNase Z 1) (tRNA 3 endonuclease 1) (ElaC homolog protein 1) (Deleted in Ma29).

RNZ1_MOUSE
NC score	0.379965 (rank : 4)	θ value	6.87365e-08 (rank : 4)
Query Neighborhood Hits	17	Target Neighborhood Hits	8	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VEB6, Q9CXB1, Q9ERF4	Gene names	Elac1
Domain Architecture
Description	Zinc phosphodiesterase ELAC protein 1 (EC 3.1.26.11) (Ribonuclease Z 1) (RNase Z 1) (tRNase Z 1) (tRNA 3 endonuclease 1) (ElaC homolog protein 1).

TYRO_HUMAN
NC score	0.070189 (rank : 5)	θ value	0.279714 (rank : 5)
Query Neighborhood Hits	17	Target Neighborhood Hits	35	Shared Neighborhood Hits	4
SwissProt Accessions	P14679, Q15675, Q15676, Q15680, Q8TAK4, Q9BYY0, Q9BZX1	Gene names	TYR
Domain Architecture
Description	Tyrosinase precursor (EC 1.14.18.1) (Monophenol monooxygenase) (Tumor rejection antigen AB) (SK29-AB) (LB24-AB).

TYRO_MOUSE
NC score	0.051690 (rank : 6)	θ value	2.36792 (rank : 10)
Query Neighborhood Hits	17	Target Neighborhood Hits	32	Shared Neighborhood Hits	4
SwissProt Accessions	P11344	Gene names	Tyr
Domain Architecture
Description	Tyrosinase precursor (EC 1.14.18.1) (Monophenol monooxygenase) (Albino locus protein).

POF1B_HUMAN
NC score	0.030857 (rank : 7)	θ value	0.47712 (rank : 6)
Query Neighborhood Hits	17	Target Neighborhood Hits	494	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WVV4, Q5H9E9, Q5H9F0, Q8NG12, Q9H5Y2, Q9H738, Q9H744	Gene names	POF1B
Domain Architecture	No domain graphic available
Description	Protein POF1B (Premature ovarian failure protein 1B).

ETV5_MOUSE
NC score	0.020845 (rank : 8)	θ value	6.88961 (rank : 13)
Query Neighborhood Hits	17	Target Neighborhood Hits	328	Shared Neighborhood Hits	4
SwissProt Accessions	Q9CXC9, Q3TG49, Q8C0F3, Q9JHB1	Gene names	Etv5
Domain Architecture	No domain graphic available
Description	ETS translocation variant 5.

TBCD4_HUMAN
NC score	0.019035 (rank : 9)	θ value	2.36792 (rank : 9)
Query Neighborhood Hits	17	Target Neighborhood Hits	357	Shared Neighborhood Hits	4
SwissProt Accessions	O60343, Q5W0B9	Gene names	TBC1D4, KIAA0603
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 4 (Akt substrate of 160 kDa) (AS160).

B4GN3_HUMAN
NC score	0.012531 (rank : 10)	θ value	6.88961 (rank : 12)
Query Neighborhood Hits	17	Target Neighborhood Hits	128	Shared Neighborhood Hits	3
SwissProt Accessions	Q6L9W6, Q6ZNC1, Q8N7T6	Gene names	B4GALNT3
Domain Architecture	No domain graphic available
Description	N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N- acetylgalactosaminyltransferase 2 (EC 2.4.1.244) (NGalNAc-T2) (Beta- 1,4-N-acetylgalactosaminyltransferase III) (Beta4GalNAc-T3) (Beta4GalNAcT3).

PB1_HUMAN
NC score	0.010518 (rank : 11)	θ value	8.99809 (rank : 16)
Query Neighborhood Hits	17	Target Neighborhood Hits	261	Shared Neighborhood Hits	2
SwissProt Accessions	Q86U86, Q9H2T3, Q9H2T4, Q9H2T5, Q9H301, Q9H314	Gene names	PB1
Domain Architecture	No domain graphic available
Description	Protein polybromo-1 (hPB1) (Polybromo-1D) (BRG1-associated factor 180) (BAF180).

RPE65_HUMAN
NC score	0.010079 (rank : 12)	θ value	8.99809 (rank : 17)
Query Neighborhood Hits	17	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	Q16518	Gene names	RPE65
Domain Architecture
Description	Retinal pigment epithelium-specific 65 kDa protein.

SRRM2_MOUSE
NC score	0.007671 (rank : 13)	θ value	6.88961 (rank : 14)
Query Neighborhood Hits	17	Target Neighborhood Hits	1470	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

JHD3B_HUMAN
NC score	0.006734 (rank : 14)	θ value	8.99809 (rank : 15)
Query Neighborhood Hits	17	Target Neighborhood Hits	128	Shared Neighborhood Hits	2
SwissProt Accessions	O94953, O75274, Q6P3R5, Q9P1V1, Q9UF40	Gene names	JMJD2B, JHDM3B, KIAA0876
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3B (EC 1.14.11.-) (Jumonji domain-containing protein 2B).

CENPE_HUMAN
NC score	0.006113 (rank : 15)	θ value	1.81305 (rank : 7)
Query Neighborhood Hits	17	Target Neighborhood Hits	2060	Shared Neighborhood Hits	5
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

TITIN_HUMAN
NC score	0.004779 (rank : 16)	θ value	1.81305 (rank : 8)
Query Neighborhood Hits	17	Target Neighborhood Hits	2923	Shared Neighborhood Hits	6
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

PCDC1_HUMAN
NC score	0.004351 (rank : 17)	θ value	4.03905 (rank : 11)
Query Neighborhood Hits	17	Target Neighborhood Hits	181	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H158, Q9Y5F5, Q9Y5I5	Gene names	PCDHAC1
Domain Architecture
Description	Protocadherin alpha C1 precursor (PCDH-alpha-C1).