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Network neighborhood for query Sequence : PNMT_MOUSE

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PNMT_MOUSE
SwissProt Accessions	P40935	Gene names	Pnmt
Domain Architecture
Description	Phenylethanolamine N-methyltransferase (EC 2.1.1.28) (PNMTase) (Noradrenaline N-methyltransferase).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PNMT_MOUSE
θ value	1.97579e-164 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	14
SwissProt Accessions	P40935	Gene names	Pnmt
Domain Architecture
Description	Phenylethanolamine N-methyltransferase (EC 2.1.1.28) (PNMTase) (Noradrenaline N-methyltransferase).

PNMT_HUMAN
θ value	1.86652e-130 (rank : 2)	NC score	0.996503 (rank : 2)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	9
SwissProt Accessions	P11086	Gene names	PNMT, PENT
Domain Architecture
Description	Phenylethanolamine N-methyltransferase (EC 2.1.1.28) (PNMTase) (Noradrenaline N-methyltransferase).

NNMT_MOUSE
θ value	7.03111e-45 (rank : 3)	NC score	0.924476 (rank : 4)
Query Neighborhood Hits	14	Target Neighborhood Hits	11	Shared Neighborhood Hits	8
SwissProt Accessions	O55239	Gene names	Nnmt
Domain Architecture
Description	Nicotinamide N-methyltransferase (EC 2.1.1.1).

INMT_HUMAN
θ value	4.55743e-44 (rank : 4)	NC score	0.928115 (rank : 3)
Query Neighborhood Hits	14	Target Neighborhood Hits	9	Shared Neighborhood Hits	6
SwissProt Accessions	O95050, Q3KP49, Q9P1Y2, Q9UBY4, Q9UHQ0	Gene names	INMT
Domain Architecture
Description	Indolethylamine N-methyltransferase (EC 2.1.1.49) (Aromatic alkylamine N-methyltransferase) (Indolamine N-methyltransferase) (Arylamine N- methyltransferase) (Amine N-methyltransferase).

NNMT_HUMAN
θ value	3.85808e-43 (rank : 5)	NC score	0.920501 (rank : 6)
Query Neighborhood Hits	14	Target Neighborhood Hits	11	Shared Neighborhood Hits	8
SwissProt Accessions	P40261	Gene names	NNMT
Domain Architecture
Description	Nicotinamide N-methyltransferase (EC 2.1.1.1).

INMT_MOUSE
θ value	2.76489e-41 (rank : 6)	NC score	0.923881 (rank : 5)
Query Neighborhood Hits	14	Target Neighborhood Hits	8	Shared Neighborhood Hits	6
SwissProt Accessions	P40936, Q9CZ50	Gene names	Inmt, Temt
Domain Architecture
Description	Indolethylamine N-methyltransferase (EC 2.1.1.49) (Aromatic alkylamine N-methyltransferase) (Indolamine N-methyltransferase) (Arylamine N- methyltransferase) (Amine N-methyltransferase).

RUSC1_HUMAN
θ value	0.365318 (rank : 7)	NC score	0.053961 (rank : 9)
Query Neighborhood Hits	14	Target Neighborhood Hits	226	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BVN2, Q9UPY4, Q9Y4T5	Gene names	RUSC1, NESCA
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 1 (New molecule containing SH3 at the carboxy-terminus) (Nesca).

METL2_HUMAN
θ value	0.47712 (rank : 8)	NC score	0.097528 (rank : 7)
Query Neighborhood Hits	14	Target Neighborhood Hits	18	Shared Neighborhood Hits	6
SwissProt Accessions	Q96IZ6, Q9H9G9, Q9NUI8, Q9P0B5	Gene names	METTL2
Domain Architecture
Description	Methyltransferase-like protein 2 (EC 2.1.1.-).

METL2_MOUSE
θ value	0.62314 (rank : 9)	NC score	0.096080 (rank : 8)
Query Neighborhood Hits	14	Target Neighborhood Hits	17	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BMK1, Q8BXC2	Gene names	Mettl2, D11Ertd768e
Domain Architecture
Description	Methyltransferase-like protein 2 (EC 2.1.1.-).

HEMGN_MOUSE
θ value	2.36792 (rank : 10)	NC score	0.030918 (rank : 11)
Query Neighborhood Hits	14	Target Neighborhood Hits	81	Shared Neighborhood Hits	2
SwissProt Accessions	Q9ERZ0, Q3TAE6, Q80YT2, Q8CF29	Gene names	Hemgn, Ndr
Domain Architecture	No domain graphic available
Description	Hemogen (Hemopoietic gene protein) (Negative differentiation regulator protein) (mNDR).

PRD16_HUMAN
θ value	4.03905 (rank : 11)	NC score	0.001044 (rank : 15)
Query Neighborhood Hits	14	Target Neighborhood Hits	832	Shared Neighborhood Hits	2
SwissProt Accessions	Q9HAZ2, Q8WYJ9, Q9C0I8	Gene names	PRDM16, KIAA1675, MEL1, PFM13
Domain Architecture
Description	PR domain zinc finger protein 16 (PR domain-containing protein 16) (Transcription factor MEL1).

ASB16_HUMAN
θ value	5.27518 (rank : 12)	NC score	0.005942 (rank : 13)
Query Neighborhood Hits	14	Target Neighborhood Hits	286	Shared Neighborhood Hits	2
SwissProt Accessions	Q96NS5, Q8WXK0	Gene names	ASB16
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 16 (ASB-16).

VINEX_HUMAN
θ value	6.88961 (rank : 13)	NC score	0.009213 (rank : 12)
Query Neighborhood Hits	14	Target Neighborhood Hits	270	Shared Neighborhood Hits	3
SwissProt Accessions	O60504, Q9UQE4	Gene names	SORBS3, SCAM1
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1).

PCDGM_HUMAN
θ value	8.99809 (rank : 14)	NC score	0.001522 (rank : 14)
Query Neighborhood Hits	14	Target Neighborhood Hits	152	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y5F6, Q9Y5C2	Gene names	PCDHGC5
Domain Architecture
Description	Protocadherin gamma C5 precursor (PCDH-gamma-C5).

METL6_HUMAN
θ value	θ > 10 (rank : 15)	NC score	0.052771 (rank : 10)
Query Neighborhood Hits	14	Target Neighborhood Hits	15	Shared Neighborhood Hits	4
SwissProt Accessions	Q8TCB7, Q96LU4	Gene names	METTL6
Domain Architecture	No domain graphic available
Description	Methyltransferase-like protein 6 (EC 2.1.1.-).

Hits sorted by NC score

PNMT_MOUSE
NC score	0.999962 (rank : 1)	θ value	1.97579e-164 (rank : 1)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	14
SwissProt Accessions	P40935	Gene names	Pnmt
Domain Architecture
Description	Phenylethanolamine N-methyltransferase (EC 2.1.1.28) (PNMTase) (Noradrenaline N-methyltransferase).

PNMT_HUMAN
NC score	0.996503 (rank : 2)	θ value	1.86652e-130 (rank : 2)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	9
SwissProt Accessions	P11086	Gene names	PNMT, PENT
Domain Architecture
Description	Phenylethanolamine N-methyltransferase (EC 2.1.1.28) (PNMTase) (Noradrenaline N-methyltransferase).

INMT_HUMAN
NC score	0.928115 (rank : 3)	θ value	4.55743e-44 (rank : 4)
Query Neighborhood Hits	14	Target Neighborhood Hits	9	Shared Neighborhood Hits	6
SwissProt Accessions	O95050, Q3KP49, Q9P1Y2, Q9UBY4, Q9UHQ0	Gene names	INMT
Domain Architecture
Description	Indolethylamine N-methyltransferase (EC 2.1.1.49) (Aromatic alkylamine N-methyltransferase) (Indolamine N-methyltransferase) (Arylamine N- methyltransferase) (Amine N-methyltransferase).

NNMT_MOUSE
NC score	0.924476 (rank : 4)	θ value	7.03111e-45 (rank : 3)
Query Neighborhood Hits	14	Target Neighborhood Hits	11	Shared Neighborhood Hits	8
SwissProt Accessions	O55239	Gene names	Nnmt
Domain Architecture
Description	Nicotinamide N-methyltransferase (EC 2.1.1.1).

INMT_MOUSE
NC score	0.923881 (rank : 5)	θ value	2.76489e-41 (rank : 6)
Query Neighborhood Hits	14	Target Neighborhood Hits	8	Shared Neighborhood Hits	6
SwissProt Accessions	P40936, Q9CZ50	Gene names	Inmt, Temt
Domain Architecture
Description	Indolethylamine N-methyltransferase (EC 2.1.1.49) (Aromatic alkylamine N-methyltransferase) (Indolamine N-methyltransferase) (Arylamine N- methyltransferase) (Amine N-methyltransferase).

NNMT_HUMAN
NC score	0.920501 (rank : 6)	θ value	3.85808e-43 (rank : 5)
Query Neighborhood Hits	14	Target Neighborhood Hits	11	Shared Neighborhood Hits	8
SwissProt Accessions	P40261	Gene names	NNMT
Domain Architecture
Description	Nicotinamide N-methyltransferase (EC 2.1.1.1).

METL2_HUMAN
NC score	0.097528 (rank : 7)	θ value	0.47712 (rank : 8)
Query Neighborhood Hits	14	Target Neighborhood Hits	18	Shared Neighborhood Hits	6
SwissProt Accessions	Q96IZ6, Q9H9G9, Q9NUI8, Q9P0B5	Gene names	METTL2
Domain Architecture
Description	Methyltransferase-like protein 2 (EC 2.1.1.-).

METL2_MOUSE
NC score	0.096080 (rank : 8)	θ value	0.62314 (rank : 9)
Query Neighborhood Hits	14	Target Neighborhood Hits	17	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BMK1, Q8BXC2	Gene names	Mettl2, D11Ertd768e
Domain Architecture
Description	Methyltransferase-like protein 2 (EC 2.1.1.-).

RUSC1_HUMAN
NC score	0.053961 (rank : 9)	θ value	0.365318 (rank : 7)
Query Neighborhood Hits	14	Target Neighborhood Hits	226	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BVN2, Q9UPY4, Q9Y4T5	Gene names	RUSC1, NESCA
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 1 (New molecule containing SH3 at the carboxy-terminus) (Nesca).

METL6_HUMAN
NC score	0.052771 (rank : 10)	θ value	θ > 10 (rank : 15)
Query Neighborhood Hits	14	Target Neighborhood Hits	15	Shared Neighborhood Hits	4
SwissProt Accessions	Q8TCB7, Q96LU4	Gene names	METTL6
Domain Architecture	No domain graphic available
Description	Methyltransferase-like protein 6 (EC 2.1.1.-).

HEMGN_MOUSE
NC score	0.030918 (rank : 11)	θ value	2.36792 (rank : 10)
Query Neighborhood Hits	14	Target Neighborhood Hits	81	Shared Neighborhood Hits	2
SwissProt Accessions	Q9ERZ0, Q3TAE6, Q80YT2, Q8CF29	Gene names	Hemgn, Ndr
Domain Architecture	No domain graphic available
Description	Hemogen (Hemopoietic gene protein) (Negative differentiation regulator protein) (mNDR).

VINEX_HUMAN
NC score	0.009213 (rank : 12)	θ value	6.88961 (rank : 13)
Query Neighborhood Hits	14	Target Neighborhood Hits	270	Shared Neighborhood Hits	3
SwissProt Accessions	O60504, Q9UQE4	Gene names	SORBS3, SCAM1
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1).

ASB16_HUMAN
NC score	0.005942 (rank : 13)	θ value	5.27518 (rank : 12)
Query Neighborhood Hits	14	Target Neighborhood Hits	286	Shared Neighborhood Hits	2
SwissProt Accessions	Q96NS5, Q8WXK0	Gene names	ASB16
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 16 (ASB-16).

PCDGM_HUMAN
NC score	0.001522 (rank : 14)	θ value	8.99809 (rank : 14)
Query Neighborhood Hits	14	Target Neighborhood Hits	152	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y5F6, Q9Y5C2	Gene names	PCDHGC5
Domain Architecture
Description	Protocadherin gamma C5 precursor (PCDH-gamma-C5).

PRD16_HUMAN
NC score	0.001044 (rank : 15)	θ value	4.03905 (rank : 11)
Query Neighborhood Hits	14	Target Neighborhood Hits	832	Shared Neighborhood Hits	2
SwissProt Accessions	Q9HAZ2, Q8WYJ9, Q9C0I8	Gene names	PRDM16, KIAA1675, MEL1, PFM13
Domain Architecture
Description	PR domain zinc finger protein 16 (PR domain-containing protein 16) (Transcription factor MEL1).