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Network neighborhood for query Sequence : NNMT_HUMAN

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NNMT_HUMAN
SwissProt Accessions	P40261	Gene names	NNMT
Domain Architecture
Description	Nicotinamide N-methyltransferase (EC 2.1.1.1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

NNMT_HUMAN
θ value	6.59259e-152 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	11	Target Neighborhood Hits	11	Shared Neighborhood Hits	11
SwissProt Accessions	P40261	Gene names	NNMT
Domain Architecture
Description	Nicotinamide N-methyltransferase (EC 2.1.1.1).

NNMT_MOUSE
θ value	6.00439e-129 (rank : 2)	NC score	0.997972 (rank : 2)
Query Neighborhood Hits	11	Target Neighborhood Hits	11	Shared Neighborhood Hits	9
SwissProt Accessions	O55239	Gene names	Nnmt
Domain Architecture
Description	Nicotinamide N-methyltransferase (EC 2.1.1.1).

INMT_MOUSE
θ value	3.23591e-74 (rank : 3)	NC score	0.982118 (rank : 3)
Query Neighborhood Hits	11	Target Neighborhood Hits	8	Shared Neighborhood Hits	6
SwissProt Accessions	P40936, Q9CZ50	Gene names	Inmt, Temt
Domain Architecture
Description	Indolethylamine N-methyltransferase (EC 2.1.1.49) (Aromatic alkylamine N-methyltransferase) (Indolamine N-methyltransferase) (Arylamine N- methyltransferase) (Amine N-methyltransferase).

INMT_HUMAN
θ value	6.7473e-72 (rank : 4)	NC score	0.978467 (rank : 4)
Query Neighborhood Hits	11	Target Neighborhood Hits	9	Shared Neighborhood Hits	7
SwissProt Accessions	O95050, Q3KP49, Q9P1Y2, Q9UBY4, Q9UHQ0	Gene names	INMT
Domain Architecture
Description	Indolethylamine N-methyltransferase (EC 2.1.1.49) (Aromatic alkylamine N-methyltransferase) (Indolamine N-methyltransferase) (Arylamine N- methyltransferase) (Amine N-methyltransferase).

PNMT_MOUSE
θ value	3.85808e-43 (rank : 5)	NC score	0.920501 (rank : 6)
Query Neighborhood Hits	11	Target Neighborhood Hits	14	Shared Neighborhood Hits	8
SwissProt Accessions	P40935	Gene names	Pnmt
Domain Architecture
Description	Phenylethanolamine N-methyltransferase (EC 2.1.1.28) (PNMTase) (Noradrenaline N-methyltransferase).

PNMT_HUMAN
θ value	8.59492e-43 (rank : 6)	NC score	0.920788 (rank : 5)
Query Neighborhood Hits	11	Target Neighborhood Hits	14	Shared Neighborhood Hits	8
SwissProt Accessions	P11086	Gene names	PNMT, PENT
Domain Architecture
Description	Phenylethanolamine N-methyltransferase (EC 2.1.1.28) (PNMTase) (Noradrenaline N-methyltransferase).

METL2_MOUSE
θ value	0.62314 (rank : 8)	NC score	0.102434 (rank : 8)
Query Neighborhood Hits	11	Target Neighborhood Hits	17	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BMK1, Q8BXC2	Gene names	Mettl2, D11Ertd768e
Domain Architecture
Description	Methyltransferase-like protein 2 (EC 2.1.1.-).

METL2_HUMAN
θ value	0.813845 (rank : 9)	NC score	0.104648 (rank : 7)
Query Neighborhood Hits	11	Target Neighborhood Hits	18	Shared Neighborhood Hits	7
SwissProt Accessions	Q96IZ6, Q9H9G9, Q9NUI8, Q9P0B5	Gene names	METTL2
Domain Architecture
Description	Methyltransferase-like protein 2 (EC 2.1.1.-).

FOXB1_MOUSE
θ value	8.99809 (rank : 11)	NC score	0.003517 (rank : 11)
Query Neighborhood Hits	11	Target Neighborhood Hits	125	Shared Neighborhood Hits	2
SwissProt Accessions	Q64732, O08753	Gene names	Foxb1, Fkh5, Foxb1a, Foxb1b, Mf3
Domain Architecture
Description	Forkhead box protein B1 (Transcription factor FKH-5).

Hits sorted by NC score

NNMT_HUMAN
NC score	0.999962 (rank : 1)	θ value	6.59259e-152 (rank : 1)
Query Neighborhood Hits	11	Target Neighborhood Hits	11	Shared Neighborhood Hits	11
SwissProt Accessions	P40261	Gene names	NNMT
Domain Architecture
Description	Nicotinamide N-methyltransferase (EC 2.1.1.1).

NNMT_MOUSE
NC score	0.997972 (rank : 2)	θ value	6.00439e-129 (rank : 2)
Query Neighborhood Hits	11	Target Neighborhood Hits	11	Shared Neighborhood Hits	9
SwissProt Accessions	O55239	Gene names	Nnmt
Domain Architecture
Description	Nicotinamide N-methyltransferase (EC 2.1.1.1).

INMT_MOUSE
NC score	0.982118 (rank : 3)	θ value	3.23591e-74 (rank : 3)
Query Neighborhood Hits	11	Target Neighborhood Hits	8	Shared Neighborhood Hits	6
SwissProt Accessions	P40936, Q9CZ50	Gene names	Inmt, Temt
Domain Architecture
Description	Indolethylamine N-methyltransferase (EC 2.1.1.49) (Aromatic alkylamine N-methyltransferase) (Indolamine N-methyltransferase) (Arylamine N- methyltransferase) (Amine N-methyltransferase).

INMT_HUMAN
NC score	0.978467 (rank : 4)	θ value	6.7473e-72 (rank : 4)
Query Neighborhood Hits	11	Target Neighborhood Hits	9	Shared Neighborhood Hits	7
SwissProt Accessions	O95050, Q3KP49, Q9P1Y2, Q9UBY4, Q9UHQ0	Gene names	INMT
Domain Architecture
Description	Indolethylamine N-methyltransferase (EC 2.1.1.49) (Aromatic alkylamine N-methyltransferase) (Indolamine N-methyltransferase) (Arylamine N- methyltransferase) (Amine N-methyltransferase).

PNMT_HUMAN
NC score	0.920788 (rank : 5)	θ value	8.59492e-43 (rank : 6)
Query Neighborhood Hits	11	Target Neighborhood Hits	14	Shared Neighborhood Hits	8
SwissProt Accessions	P11086	Gene names	PNMT, PENT
Domain Architecture
Description	Phenylethanolamine N-methyltransferase (EC 2.1.1.28) (PNMTase) (Noradrenaline N-methyltransferase).

PNMT_MOUSE
NC score	0.920501 (rank : 6)	θ value	3.85808e-43 (rank : 5)
Query Neighborhood Hits	11	Target Neighborhood Hits	14	Shared Neighborhood Hits	8
SwissProt Accessions	P40935	Gene names	Pnmt
Domain Architecture
Description	Phenylethanolamine N-methyltransferase (EC 2.1.1.28) (PNMTase) (Noradrenaline N-methyltransferase).

METL2_HUMAN
NC score	0.104648 (rank : 7)	θ value	0.813845 (rank : 9)
Query Neighborhood Hits	11	Target Neighborhood Hits	18	Shared Neighborhood Hits	7
SwissProt Accessions	Q96IZ6, Q9H9G9, Q9NUI8, Q9P0B5	Gene names	METTL2
Domain Architecture
Description	Methyltransferase-like protein 2 (EC 2.1.1.-).

METL2_MOUSE
NC score	0.102434 (rank : 8)	θ value	0.62314 (rank : 8)
Query Neighborhood Hits	11	Target Neighborhood Hits	17	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BMK1, Q8BXC2	Gene names	Mettl2, D11Ertd768e
Domain Architecture
Description	Methyltransferase-like protein 2 (EC 2.1.1.-).

FOXB1_MOUSE
NC score	0.003517 (rank : 11)	θ value	8.99809 (rank : 11)
Query Neighborhood Hits	11	Target Neighborhood Hits	125	Shared Neighborhood Hits	2
SwissProt Accessions	Q64732, O08753	Gene names	Foxb1, Fkh5, Foxb1a, Foxb1b, Mf3
Domain Architecture
Description	Forkhead box protein B1 (Transcription factor FKH-5).