Please be patient as the page loads

Stop Image Loading/Displaying

Network neighborhood for query Sequence : PNMT_HUMAN

For an explanation of this page, click here

PNMT_HUMAN
SwissProt Accessions	P11086	Gene names	PNMT, PENT
Domain Architecture
Description	Phenylethanolamine N-methyltransferase (EC 2.1.1.28) (PNMTase) (Noradrenaline N-methyltransferase).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PNMT_HUMAN
θ value	1.85358e-154 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	14
SwissProt Accessions	P11086	Gene names	PNMT, PENT
Domain Architecture
Description	Phenylethanolamine N-methyltransferase (EC 2.1.1.28) (PNMTase) (Noradrenaline N-methyltransferase).

PNMT_MOUSE
θ value	1.86652e-130 (rank : 2)	NC score	0.996503 (rank : 2)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	9
SwissProt Accessions	P40935	Gene names	Pnmt
Domain Architecture
Description	Phenylethanolamine N-methyltransferase (EC 2.1.1.28) (PNMTase) (Noradrenaline N-methyltransferase).

NNMT_MOUSE
θ value	1.41672e-45 (rank : 3)	NC score	0.924928 (rank : 4)
Query Neighborhood Hits	14	Target Neighborhood Hits	11	Shared Neighborhood Hits	8
SwissProt Accessions	O55239	Gene names	Nnmt
Domain Architecture
Description	Nicotinamide N-methyltransferase (EC 2.1.1.1).

INMT_HUMAN
θ value	2.04573e-44 (rank : 4)	NC score	0.928252 (rank : 3)
Query Neighborhood Hits	14	Target Neighborhood Hits	9	Shared Neighborhood Hits	6
SwissProt Accessions	O95050, Q3KP49, Q9P1Y2, Q9UBY4, Q9UHQ0	Gene names	INMT
Domain Architecture
Description	Indolethylamine N-methyltransferase (EC 2.1.1.49) (Aromatic alkylamine N-methyltransferase) (Indolamine N-methyltransferase) (Arylamine N- methyltransferase) (Amine N-methyltransferase).

NNMT_HUMAN
θ value	8.59492e-43 (rank : 5)	NC score	0.920788 (rank : 6)
Query Neighborhood Hits	14	Target Neighborhood Hits	11	Shared Neighborhood Hits	8
SwissProt Accessions	P40261	Gene names	NNMT
Domain Architecture
Description	Nicotinamide N-methyltransferase (EC 2.1.1.1).

INMT_MOUSE
θ value	1.98146e-39 (rank : 6)	NC score	0.923105 (rank : 5)
Query Neighborhood Hits	14	Target Neighborhood Hits	8	Shared Neighborhood Hits	6
SwissProt Accessions	P40936, Q9CZ50	Gene names	Inmt, Temt
Domain Architecture
Description	Indolethylamine N-methyltransferase (EC 2.1.1.49) (Aromatic alkylamine N-methyltransferase) (Indolamine N-methyltransferase) (Arylamine N- methyltransferase) (Amine N-methyltransferase).

RUSC1_HUMAN
θ value	0.0961366 (rank : 7)	NC score	0.059183 (rank : 9)
Query Neighborhood Hits	14	Target Neighborhood Hits	226	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BVN2, Q9UPY4, Q9Y4T5	Gene names	RUSC1, NESCA
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 1 (New molecule containing SH3 at the carboxy-terminus) (Nesca).

DYH9_HUMAN
θ value	0.21417 (rank : 8)	NC score	0.030264 (rank : 12)
Query Neighborhood Hits	14	Target Neighborhood Hits	291	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NYC9, O95494, Q9NQ28	Gene names	DNAH9, DNAH17L, DNAL1
Domain Architecture
Description	Ciliary dynein heavy chain 9 (Axonemal beta dynein heavy chain 9).

METL2_MOUSE
θ value	0.47712 (rank : 9)	NC score	0.096470 (rank : 8)
Query Neighborhood Hits	14	Target Neighborhood Hits	17	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BMK1, Q8BXC2	Gene names	Mettl2, D11Ertd768e
Domain Architecture
Description	Methyltransferase-like protein 2 (EC 2.1.1.-).

METL2_HUMAN
θ value	0.62314 (rank : 10)	NC score	0.097577 (rank : 7)
Query Neighborhood Hits	14	Target Neighborhood Hits	18	Shared Neighborhood Hits	6
SwissProt Accessions	Q96IZ6, Q9H9G9, Q9NUI8, Q9P0B5	Gene names	METTL2
Domain Architecture
Description	Methyltransferase-like protein 2 (EC 2.1.1.-).

RAI1_HUMAN
θ value	1.38821 (rank : 11)	NC score	0.032266 (rank : 11)
Query Neighborhood Hits	14	Target Neighborhood Hits	360	Shared Neighborhood Hits	3
SwissProt Accessions	Q7Z5J4, Q8N3B4, Q8ND08, Q8WU64, Q96JK5, Q9H1C1, Q9H1C2, Q9UF69	Gene names	RAI1, KIAA1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

ATG7_MOUSE
θ value	3.0926 (rank : 12)	NC score	0.023850 (rank : 14)
Query Neighborhood Hits	14	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D906, Q3TCD9, Q8K4Q5	Gene names	Atg7, Apg7l
Domain Architecture	No domain graphic available
Description	Autophagy-related protein 7 (APG7-like) (Ubiquitin-activating enzyme E1-like protein) (mAGP7).

FLCN_MOUSE
θ value	5.27518 (rank : 13)	NC score	0.019064 (rank : 15)
Query Neighborhood Hits	14	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q8QZS3, Q3U4U8, Q3UFZ1, Q5SWZ2, Q5SX01, Q5SX02, Q8CAC0	Gene names	Flcn
Domain Architecture	No domain graphic available
Description	Folliculin.

RAI1_MOUSE
θ value	5.27518 (rank : 14)	NC score	0.028744 (rank : 13)
Query Neighborhood Hits	14	Target Neighborhood Hits	344	Shared Neighborhood Hits	3
SwissProt Accessions	Q61818, Q6ZPH7, Q8CEV1	Gene names	Rai1, Kiaa1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

METL6_HUMAN
θ value	θ > 10 (rank : 15)	NC score	0.053052 (rank : 10)
Query Neighborhood Hits	14	Target Neighborhood Hits	15	Shared Neighborhood Hits	4
SwissProt Accessions	Q8TCB7, Q96LU4	Gene names	METTL6
Domain Architecture	No domain graphic available
Description	Methyltransferase-like protein 6 (EC 2.1.1.-).

Hits sorted by NC score

PNMT_HUMAN
NC score	0.999962 (rank : 1)	θ value	1.85358e-154 (rank : 1)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	14
SwissProt Accessions	P11086	Gene names	PNMT, PENT
Domain Architecture
Description	Phenylethanolamine N-methyltransferase (EC 2.1.1.28) (PNMTase) (Noradrenaline N-methyltransferase).

PNMT_MOUSE
NC score	0.996503 (rank : 2)	θ value	1.86652e-130 (rank : 2)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	9
SwissProt Accessions	P40935	Gene names	Pnmt
Domain Architecture
Description	Phenylethanolamine N-methyltransferase (EC 2.1.1.28) (PNMTase) (Noradrenaline N-methyltransferase).

INMT_HUMAN
NC score	0.928252 (rank : 3)	θ value	2.04573e-44 (rank : 4)
Query Neighborhood Hits	14	Target Neighborhood Hits	9	Shared Neighborhood Hits	6
SwissProt Accessions	O95050, Q3KP49, Q9P1Y2, Q9UBY4, Q9UHQ0	Gene names	INMT
Domain Architecture
Description	Indolethylamine N-methyltransferase (EC 2.1.1.49) (Aromatic alkylamine N-methyltransferase) (Indolamine N-methyltransferase) (Arylamine N- methyltransferase) (Amine N-methyltransferase).

NNMT_MOUSE
NC score	0.924928 (rank : 4)	θ value	1.41672e-45 (rank : 3)
Query Neighborhood Hits	14	Target Neighborhood Hits	11	Shared Neighborhood Hits	8
SwissProt Accessions	O55239	Gene names	Nnmt
Domain Architecture
Description	Nicotinamide N-methyltransferase (EC 2.1.1.1).

INMT_MOUSE
NC score	0.923105 (rank : 5)	θ value	1.98146e-39 (rank : 6)
Query Neighborhood Hits	14	Target Neighborhood Hits	8	Shared Neighborhood Hits	6
SwissProt Accessions	P40936, Q9CZ50	Gene names	Inmt, Temt
Domain Architecture
Description	Indolethylamine N-methyltransferase (EC 2.1.1.49) (Aromatic alkylamine N-methyltransferase) (Indolamine N-methyltransferase) (Arylamine N- methyltransferase) (Amine N-methyltransferase).

NNMT_HUMAN
NC score	0.920788 (rank : 6)	θ value	8.59492e-43 (rank : 5)
Query Neighborhood Hits	14	Target Neighborhood Hits	11	Shared Neighborhood Hits	8
SwissProt Accessions	P40261	Gene names	NNMT
Domain Architecture
Description	Nicotinamide N-methyltransferase (EC 2.1.1.1).

METL2_HUMAN
NC score	0.097577 (rank : 7)	θ value	0.62314 (rank : 10)
Query Neighborhood Hits	14	Target Neighborhood Hits	18	Shared Neighborhood Hits	6
SwissProt Accessions	Q96IZ6, Q9H9G9, Q9NUI8, Q9P0B5	Gene names	METTL2
Domain Architecture
Description	Methyltransferase-like protein 2 (EC 2.1.1.-).

METL2_MOUSE
NC score	0.096470 (rank : 8)	θ value	0.47712 (rank : 9)
Query Neighborhood Hits	14	Target Neighborhood Hits	17	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BMK1, Q8BXC2	Gene names	Mettl2, D11Ertd768e
Domain Architecture
Description	Methyltransferase-like protein 2 (EC 2.1.1.-).

RUSC1_HUMAN
NC score	0.059183 (rank : 9)	θ value	0.0961366 (rank : 7)
Query Neighborhood Hits	14	Target Neighborhood Hits	226	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BVN2, Q9UPY4, Q9Y4T5	Gene names	RUSC1, NESCA
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 1 (New molecule containing SH3 at the carboxy-terminus) (Nesca).

METL6_HUMAN
NC score	0.053052 (rank : 10)	θ value	θ > 10 (rank : 15)
Query Neighborhood Hits	14	Target Neighborhood Hits	15	Shared Neighborhood Hits	4
SwissProt Accessions	Q8TCB7, Q96LU4	Gene names	METTL6
Domain Architecture	No domain graphic available
Description	Methyltransferase-like protein 6 (EC 2.1.1.-).

RAI1_HUMAN
NC score	0.032266 (rank : 11)	θ value	1.38821 (rank : 11)
Query Neighborhood Hits	14	Target Neighborhood Hits	360	Shared Neighborhood Hits	3
SwissProt Accessions	Q7Z5J4, Q8N3B4, Q8ND08, Q8WU64, Q96JK5, Q9H1C1, Q9H1C2, Q9UF69	Gene names	RAI1, KIAA1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

DYH9_HUMAN
NC score	0.030264 (rank : 12)	θ value	0.21417 (rank : 8)
Query Neighborhood Hits	14	Target Neighborhood Hits	291	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NYC9, O95494, Q9NQ28	Gene names	DNAH9, DNAH17L, DNAL1
Domain Architecture
Description	Ciliary dynein heavy chain 9 (Axonemal beta dynein heavy chain 9).

RAI1_MOUSE
NC score	0.028744 (rank : 13)	θ value	5.27518 (rank : 14)
Query Neighborhood Hits	14	Target Neighborhood Hits	344	Shared Neighborhood Hits	3
SwissProt Accessions	Q61818, Q6ZPH7, Q8CEV1	Gene names	Rai1, Kiaa1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

ATG7_MOUSE
NC score	0.023850 (rank : 14)	θ value	3.0926 (rank : 12)
Query Neighborhood Hits	14	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D906, Q3TCD9, Q8K4Q5	Gene names	Atg7, Apg7l
Domain Architecture	No domain graphic available
Description	Autophagy-related protein 7 (APG7-like) (Ubiquitin-activating enzyme E1-like protein) (mAGP7).

FLCN_MOUSE
NC score	0.019064 (rank : 15)	θ value	5.27518 (rank : 13)
Query Neighborhood Hits	14	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q8QZS3, Q3U4U8, Q3UFZ1, Q5SWZ2, Q5SX01, Q5SX02, Q8CAC0	Gene names	Flcn
Domain Architecture	No domain graphic available
Description	Folliculin.