Please be patient as the page loads

Stop Image Loading/Displaying

Network neighborhood for query Sequence : PEPA_HUMAN

For an explanation of this page, click here

PEPA_HUMAN
 
SwissProt Accessions P00790, Q8N1E3 Gene names PGA3
Domain
Architecture
Description Pepsin A precursor (EC 3.4.23.1).
Rank Plots


Hits sorted by θ


PEPA_HUMAN
 
θ value 0 (rank : 1) NC score 0.999962 (rank : 1)
Query Neighborhood Hits 22 Target Neighborhood Hits 22 Shared Neighborhood Hits 22
SwissProt Accessions P00790, Q8N1E3 Gene names PGA3
Domain
Architecture
Description Pepsin A precursor (EC 3.4.23.1).
PEPC_MOUSE
 
θ value 3.91003e-112 (rank : 2) NC score 0.991896 (rank : 3)
Query Neighborhood Hits 22 Target Neighborhood Hits 17 Shared Neighborhood Hits 15
SwissProt Accessions Q9D7R7, Q9D7T2 Gene names Pgc, Upg1
Domain
Architecture

No domain graphic available

Description Gastricsin precursor (EC 3.4.23.3) (Pepsinogen C).
CATE_HUMAN
 
θ value 6.6695e-112 (rank : 3) NC score 0.992191 (rank : 2)
Query Neighborhood Hits 22 Target Neighborhood Hits 20 Shared Neighborhood Hits 15
SwissProt Accessions P14091, Q9NY58 Gene names CTSE
Domain
Architecture
Description Cathepsin E precursor (EC 3.4.23.34).
CATE_MOUSE
 
θ value 1.64275e-110 (rank : 4) NC score 0.991776 (rank : 4)
Query Neighborhood Hits 22 Target Neighborhood Hits 19 Shared Neighborhood Hits 15
SwissProt Accessions P70269, O35647 Gene names Ctse
Domain
Architecture
Description Cathepsin E precursor (EC 3.4.23.34).
PEPC_HUMAN
 
θ value 5.84277e-108 (rank : 5) NC score 0.990883 (rank : 5)
Query Neighborhood Hits 22 Target Neighborhood Hits 18 Shared Neighborhood Hits 15
SwissProt Accessions P20142, Q5T3D7, Q5T3D8 Gene names PGC
Domain
Architecture
Description Gastricsin precursor (EC 3.4.23.3) (Pepsinogen C).
CATD_MOUSE
 
θ value 4.49445e-92 (rank : 6) NC score 0.985886 (rank : 6)
Query Neighborhood Hits 22 Target Neighborhood Hits 17 Shared Neighborhood Hits 15
SwissProt Accessions P18242 Gene names Ctsd
Domain
Architecture
Description Cathepsin D precursor (EC 3.4.23.5).
CATD_HUMAN
 
θ value 4.96919e-91 (rank : 7) NC score 0.985298 (rank : 7)
Query Neighborhood Hits 22 Target Neighborhood Hits 17 Shared Neighborhood Hits 15
SwissProt Accessions P07339, Q6IB57 Gene names CTSD
Domain
Architecture
Description Cathepsin D precursor (EC 3.4.23.5) [Contains: Cathepsin D light chain; Cathepsin D heavy chain].
NAPSA_HUMAN
 
θ value 4.08394e-77 (rank : 8) NC score 0.976601 (rank : 9)
Query Neighborhood Hits 22 Target Neighborhood Hits 17 Shared Neighborhood Hits 15
SwissProt Accessions O96009 Gene names NAPSA, NAP1
Domain
Architecture
Description Napsin-A precursor (EC 3.4.23.-) (Napsin-1) (NAPA) (TA01/TA02) (Aspartyl protease 4) (Asp 4) (ASP4).
NAPSA_MOUSE
 
θ value 9.0981e-77 (rank : 9) NC score 0.978685 (rank : 8)
Query Neighborhood Hits 22 Target Neighborhood Hits 16 Shared Neighborhood Hits 15
SwissProt Accessions O09043 Gene names Napsa, Kdap, Nap
Domain
Architecture
Description Napsin-A precursor (EC 3.4.23.-) (Kidney-derived aspartic protease- like protein) (KDAP-1) (KAP).
RENI2_MOUSE
 
θ value 1.04096e-72 (rank : 10) NC score 0.971571 (rank : 10)
Query Neighborhood Hits 22 Target Neighborhood Hits 20 Shared Neighborhood Hits 15
SwissProt Accessions P00796, P70229, P97955, Q62155 Gene names Ren2, Ren-2
Domain
Architecture
Description Renin-2 precursor (EC 3.4.23.15) (Angiotensinogenase) (Submandibular gland renin) [Contains: Renin-2 heavy chain; Renin-2 light chain].
RENI1_MOUSE
 
θ value 3.95564e-72 (rank : 11) NC score 0.971190 (rank : 12)
Query Neighborhood Hits 22 Target Neighborhood Hits 19 Shared Neighborhood Hits 15
SwissProt Accessions P06281, P97911, Q543E5, Q62153, Q62154 Gene names Ren1, Ren, Ren-1
Domain
Architecture
Description Renin-1 precursor (EC 3.4.23.15) (Angiotensinogenase) (Kidney renin).
RENI_HUMAN
 
θ value 6.98233e-69 (rank : 12) NC score 0.971552 (rank : 11)
Query Neighborhood Hits 22 Target Neighborhood Hits 15 Shared Neighborhood Hits 15
SwissProt Accessions P00797, Q6T5C2 Gene names REN
Domain
Architecture
Description Renin precursor (EC 3.4.23.15) (Angiotensinogenase).
BACE2_HUMAN
 
θ value 4.15078e-21 (rank : 13) NC score 0.804578 (rank : 13)
Query Neighborhood Hits 22 Target Neighborhood Hits 20 Shared Neighborhood Hits 15
SwissProt Accessions Q9Y5Z0, Q9UJT6 Gene names BACE2, ASP21
Domain
Architecture
Description Beta-secretase 2 precursor (EC 3.4.23.45) (Beta-site APP-cleaving enzyme 2) (Aspartyl protease 1) (Asp 1) (ASP1) (Membrane-associated aspartic protease 1) (Memapsin-1) (Down region aspartic protease).
BACE1_HUMAN
 
θ value 3.51386e-20 (rank : 14) NC score 0.739401 (rank : 15)
Query Neighborhood Hits 22 Target Neighborhood Hits 18 Shared Neighborhood Hits 15
SwissProt Accessions P56817, Q9BYB9, Q9BYC0, Q9BYC1, Q9UJT5 Gene names BACE1, BACE
Domain
Architecture
Description Beta-secretase 1 precursor (EC 3.4.23.46) (Beta-site APP cleaving enzyme 1) (Beta-site amyloid precursor protein cleaving enzyme 1) (Membrane-associated aspartic protease 2) (Memapsin-2) (Aspartyl protease 2) (Asp 2) (ASP2).
BACE1_MOUSE
 
θ value 7.82807e-20 (rank : 15) NC score 0.740406 (rank : 14)
Query Neighborhood Hits 22 Target Neighborhood Hits 18 Shared Neighborhood Hits 15
SwissProt Accessions P56818, Q544D0 Gene names Bace1, Bace
Domain
Architecture
Description Beta-secretase 1 precursor (EC 3.4.23.46) (Beta-site APP cleaving enzyme 1) (Beta-site amyloid precursor protein cleaving enzyme 1) (Membrane-associated aspartic protease 2) (Memapsin-2) (Aspartyl protease 2) (Asp 2) (ASP2).
BRCA2_HUMAN
 
θ value 0.813845 (rank : 16) NC score 0.020626 (rank : 16)
Query Neighborhood Hits 22 Target Neighborhood Hits 202 Shared Neighborhood Hits 2
SwissProt Accessions P51587, O00183, O15008, Q13879 Gene names BRCA2, FANCD1
Domain
Architecture
Description Breast cancer type 2 susceptibility protein (Fanconi anemia group D1 protein).
ACPH_HUMAN
 
θ value 1.38821 (rank : 17) NC score 0.018839 (rank : 17)
Query Neighborhood Hits 22 Target Neighborhood Hits 30 Shared Neighborhood Hits 2
SwissProt Accessions P13798, Q9BQ33, Q9P0Y2 Gene names APEH
Domain
Architecture
Description Acylamino-acid-releasing enzyme (EC 3.4.19.1) (AARE) (Acyl-peptide hydrolase) (APH) (Acylaminoacyl-peptidase) (Oxidized protein hydrolase) (OPH) (DNF15S2 protein).
NUAK2_HUMAN
 
θ value 6.88961 (rank : 18) NC score -0.002230 (rank : 22)
Query Neighborhood Hits 22 Target Neighborhood Hits 874 Shared Neighborhood Hits 3
SwissProt Accessions Q9H093 Gene names NUAK2
Domain
Architecture

No domain graphic available

Description NUAK family SNF1-like kinase 2 (EC 2.7.11.1) (SNF1/AMP kinase-related kinase) (SNARK).
TSSK4_MOUSE
 
θ value 6.88961 (rank : 19) NC score -0.001995 (rank : 21)
Query Neighborhood Hits 22 Target Neighborhood Hits 840 Shared Neighborhood Hits 3
SwissProt Accessions Q9D411 Gene names Tssk4
Domain
Architecture

No domain graphic available

Description Testis-specific serine/threonine-protein kinase 4 (EC 2.7.11.1) (TSSK- 4) (Testis-specific kinase 4) (TSK-4).
LHX4_HUMAN
 
θ value 8.99809 (rank : 20) NC score 0.001831 (rank : 20)
Query Neighborhood Hits 22 Target Neighborhood Hits 455 Shared Neighborhood Hits 3
SwissProt Accessions Q969G2, Q8NHE0, Q8TCJ1, Q8WWX2, Q969W2 Gene names LHX4
Domain
Architecture
Description LIM/homeobox protein Lhx4.
LHX4_MOUSE
 
θ value 8.99809 (rank : 21) NC score 0.001832 (rank : 19)
Query Neighborhood Hits 22 Target Neighborhood Hits 457 Shared Neighborhood Hits 3
SwissProt Accessions P53776, O08916, Q9R280 Gene names Lhx4, Gsh-4, Gsh4
Domain
Architecture
Description LIM/homeobox protein Lhx4.
TIF1A_MOUSE
 
θ value 8.99809 (rank : 22) NC score 0.002317 (rank : 18)
Query Neighborhood Hits 22 Target Neighborhood Hits 307 Shared Neighborhood Hits 2
SwissProt Accessions Q64127, Q64126 Gene names Trim24, Tif1, Tif1a
Domain
Architecture
Description Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24).

Hits sorted by NC score


PEPA_HUMAN
 
NC score 0.999962 (rank : 1) θ value 0 (rank : 1)
Query Neighborhood Hits 22 Target Neighborhood Hits 22 Shared Neighborhood Hits 22
SwissProt Accessions P00790, Q8N1E3 Gene names PGA3
Domain
Architecture
Description Pepsin A precursor (EC 3.4.23.1).
CATE_HUMAN
 
NC score 0.992191 (rank : 2) θ value 6.6695e-112 (rank : 3)
Query Neighborhood Hits 22 Target Neighborhood Hits 20 Shared Neighborhood Hits 15
SwissProt Accessions P14091, Q9NY58 Gene names CTSE
Domain
Architecture
Description Cathepsin E precursor (EC 3.4.23.34).
PEPC_MOUSE
 
NC score 0.991896 (rank : 3) θ value 3.91003e-112 (rank : 2)
Query Neighborhood Hits 22 Target Neighborhood Hits 17 Shared Neighborhood Hits 15
SwissProt Accessions Q9D7R7, Q9D7T2 Gene names Pgc, Upg1
Domain
Architecture

No domain graphic available

Description Gastricsin precursor (EC 3.4.23.3) (Pepsinogen C).
CATE_MOUSE
 
NC score 0.991776 (rank : 4) θ value 1.64275e-110 (rank : 4)
Query Neighborhood Hits 22 Target Neighborhood Hits 19 Shared Neighborhood Hits 15
SwissProt Accessions P70269, O35647 Gene names Ctse
Domain
Architecture
Description Cathepsin E precursor (EC 3.4.23.34).
PEPC_HUMAN
 
NC score 0.990883 (rank : 5) θ value 5.84277e-108 (rank : 5)
Query Neighborhood Hits 22 Target Neighborhood Hits 18 Shared Neighborhood Hits 15
SwissProt Accessions P20142, Q5T3D7, Q5T3D8 Gene names PGC
Domain
Architecture
Description Gastricsin precursor (EC 3.4.23.3) (Pepsinogen C).
CATD_MOUSE
 
NC score 0.985886 (rank : 6) θ value 4.49445e-92 (rank : 6)
Query Neighborhood Hits 22 Target Neighborhood Hits 17 Shared Neighborhood Hits 15
SwissProt Accessions P18242 Gene names Ctsd
Domain
Architecture
Description Cathepsin D precursor (EC 3.4.23.5).
CATD_HUMAN
 
NC score 0.985298 (rank : 7) θ value 4.96919e-91 (rank : 7)
Query Neighborhood Hits 22 Target Neighborhood Hits 17 Shared Neighborhood Hits 15
SwissProt Accessions P07339, Q6IB57 Gene names CTSD
Domain
Architecture
Description Cathepsin D precursor (EC 3.4.23.5) [Contains: Cathepsin D light chain; Cathepsin D heavy chain].
NAPSA_MOUSE
 
NC score 0.978685 (rank : 8) θ value 9.0981e-77 (rank : 9)
Query Neighborhood Hits 22 Target Neighborhood Hits 16 Shared Neighborhood Hits 15
SwissProt Accessions O09043 Gene names Napsa, Kdap, Nap
Domain
Architecture
Description Napsin-A precursor (EC 3.4.23.-) (Kidney-derived aspartic protease- like protein) (KDAP-1) (KAP).
NAPSA_HUMAN
 
NC score 0.976601 (rank : 9) θ value 4.08394e-77 (rank : 8)
Query Neighborhood Hits 22 Target Neighborhood Hits 17 Shared Neighborhood Hits 15
SwissProt Accessions O96009 Gene names NAPSA, NAP1
Domain
Architecture
Description Napsin-A precursor (EC 3.4.23.-) (Napsin-1) (NAPA) (TA01/TA02) (Aspartyl protease 4) (Asp 4) (ASP4).
RENI2_MOUSE
 
NC score 0.971571 (rank : 10) θ value 1.04096e-72 (rank : 10)
Query Neighborhood Hits 22 Target Neighborhood Hits 20 Shared Neighborhood Hits 15
SwissProt Accessions P00796, P70229, P97955, Q62155 Gene names Ren2, Ren-2
Domain
Architecture
Description Renin-2 precursor (EC 3.4.23.15) (Angiotensinogenase) (Submandibular gland renin) [Contains: Renin-2 heavy chain; Renin-2 light chain].
RENI_HUMAN
 
NC score 0.971552 (rank : 11) θ value 6.98233e-69 (rank : 12)
Query Neighborhood Hits 22 Target Neighborhood Hits 15 Shared Neighborhood Hits 15
SwissProt Accessions P00797, Q6T5C2 Gene names REN
Domain
Architecture
Description Renin precursor (EC 3.4.23.15) (Angiotensinogenase).
RENI1_MOUSE
 
NC score 0.971190 (rank : 12) θ value 3.95564e-72 (rank : 11)
Query Neighborhood Hits 22 Target Neighborhood Hits 19 Shared Neighborhood Hits 15
SwissProt Accessions P06281, P97911, Q543E5, Q62153, Q62154 Gene names Ren1, Ren, Ren-1
Domain
Architecture
Description Renin-1 precursor (EC 3.4.23.15) (Angiotensinogenase) (Kidney renin).
BACE2_HUMAN
 
NC score 0.804578 (rank : 13) θ value 4.15078e-21 (rank : 13)
Query Neighborhood Hits 22 Target Neighborhood Hits 20 Shared Neighborhood Hits 15
SwissProt Accessions Q9Y5Z0, Q9UJT6 Gene names BACE2, ASP21
Domain
Architecture
Description Beta-secretase 2 precursor (EC 3.4.23.45) (Beta-site APP-cleaving enzyme 2) (Aspartyl protease 1) (Asp 1) (ASP1) (Membrane-associated aspartic protease 1) (Memapsin-1) (Down region aspartic protease).
BACE1_MOUSE
 
NC score 0.740406 (rank : 14) θ value 7.82807e-20 (rank : 15)
Query Neighborhood Hits 22 Target Neighborhood Hits 18 Shared Neighborhood Hits 15
SwissProt Accessions P56818, Q544D0 Gene names Bace1, Bace
Domain
Architecture
Description Beta-secretase 1 precursor (EC 3.4.23.46) (Beta-site APP cleaving enzyme 1) (Beta-site amyloid precursor protein cleaving enzyme 1) (Membrane-associated aspartic protease 2) (Memapsin-2) (Aspartyl protease 2) (Asp 2) (ASP2).
BACE1_HUMAN
 
NC score 0.739401 (rank : 15) θ value 3.51386e-20 (rank : 14)
Query Neighborhood Hits 22 Target Neighborhood Hits 18 Shared Neighborhood Hits 15
SwissProt Accessions P56817, Q9BYB9, Q9BYC0, Q9BYC1, Q9UJT5 Gene names BACE1, BACE
Domain
Architecture
Description Beta-secretase 1 precursor (EC 3.4.23.46) (Beta-site APP cleaving enzyme 1) (Beta-site amyloid precursor protein cleaving enzyme 1) (Membrane-associated aspartic protease 2) (Memapsin-2) (Aspartyl protease 2) (Asp 2) (ASP2).
BRCA2_HUMAN
 
NC score 0.020626 (rank : 16) θ value 0.813845 (rank : 16)
Query Neighborhood Hits 22 Target Neighborhood Hits 202 Shared Neighborhood Hits 2
SwissProt Accessions P51587, O00183, O15008, Q13879 Gene names BRCA2, FANCD1
Domain
Architecture
Description Breast cancer type 2 susceptibility protein (Fanconi anemia group D1 protein).
ACPH_HUMAN
 
NC score 0.018839 (rank : 17) θ value 1.38821 (rank : 17)
Query Neighborhood Hits 22 Target Neighborhood Hits 30 Shared Neighborhood Hits 2
SwissProt Accessions P13798, Q9BQ33, Q9P0Y2 Gene names APEH
Domain
Architecture
Description Acylamino-acid-releasing enzyme (EC 3.4.19.1) (AARE) (Acyl-peptide hydrolase) (APH) (Acylaminoacyl-peptidase) (Oxidized protein hydrolase) (OPH) (DNF15S2 protein).
TIF1A_MOUSE
 
NC score 0.002317 (rank : 18) θ value 8.99809 (rank : 22)
Query Neighborhood Hits 22 Target Neighborhood Hits 307 Shared Neighborhood Hits 2
SwissProt Accessions Q64127, Q64126 Gene names Trim24, Tif1, Tif1a
Domain
Architecture
Description Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24).
LHX4_MOUSE
 
NC score 0.001832 (rank : 19) θ value 8.99809 (rank : 21)
Query Neighborhood Hits 22 Target Neighborhood Hits 457 Shared Neighborhood Hits 3
SwissProt Accessions P53776, O08916, Q9R280 Gene names Lhx4, Gsh-4, Gsh4
Domain
Architecture
Description LIM/homeobox protein Lhx4.
LHX4_HUMAN
 
NC score 0.001831 (rank : 20) θ value 8.99809 (rank : 20)
Query Neighborhood Hits 22 Target Neighborhood Hits 455 Shared Neighborhood Hits 3
SwissProt Accessions Q969G2, Q8NHE0, Q8TCJ1, Q8WWX2, Q969W2 Gene names LHX4
Domain
Architecture
Description LIM/homeobox protein Lhx4.
TSSK4_MOUSE
 
NC score -0.001995 (rank : 21) θ value 6.88961 (rank : 19)
Query Neighborhood Hits 22 Target Neighborhood Hits 840 Shared Neighborhood Hits 3
SwissProt Accessions Q9D411 Gene names Tssk4
Domain
Architecture

No domain graphic available

Description Testis-specific serine/threonine-protein kinase 4 (EC 2.7.11.1) (TSSK- 4) (Testis-specific kinase 4) (TSK-4).
NUAK2_HUMAN
 
NC score -0.002230 (rank : 22) θ value 6.88961 (rank : 18)
Query Neighborhood Hits 22 Target Neighborhood Hits 874 Shared Neighborhood Hits 3
SwissProt Accessions Q9H093 Gene names NUAK2
Domain
Architecture

No domain graphic available

Description NUAK family SNF1-like kinase 2 (EC 2.7.11.1) (SNF1/AMP kinase-related kinase) (SNARK).