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Network neighborhood for query Sequence : OPLA_HUMAN

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OPLA_HUMAN
SwissProt Accessions	O14841, Q75W65, Q9Y4Q0	Gene names	OPLAH
Domain Architecture	No domain graphic available
Description	5-oxoprolinase (EC 3.5.2.9) (5-oxo-L-prolinase) (Pyroglutamase) (5- OPase).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

OPLA_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	17	Target Neighborhood Hits	17	Shared Neighborhood Hits	17
SwissProt Accessions	O14841, Q75W65, Q9Y4Q0	Gene names	OPLAH
Domain Architecture	No domain graphic available
Description	5-oxoprolinase (EC 3.5.2.9) (5-oxo-L-prolinase) (Pyroglutamase) (5- OPase).

OPLA_MOUSE
θ value	0 (rank : 2)	NC score	0.998751 (rank : 2)
Query Neighborhood Hits	17	Target Neighborhood Hits	14	Shared Neighborhood Hits	9
SwissProt Accessions	Q8K010, Q8R3K2	Gene names	Oplah
Domain Architecture
Description	5-oxoprolinase (EC 3.5.2.9) (5-oxo-L-prolinase) (Pyroglutamase) (5- OPase).

CI082_HUMAN
θ value	1.38821 (rank : 3)	NC score	0.041782 (rank : 4)
Query Neighborhood Hits	17	Target Neighborhood Hits	32	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H8G2, Q5VY32, Q6IPE6, Q96C59	Gene names	C9orf82
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf82.

INSM1_MOUSE
θ value	1.38821 (rank : 4)	NC score	0.018448 (rank : 11)
Query Neighborhood Hits	17	Target Neighborhood Hits	678	Shared Neighborhood Hits	4
SwissProt Accessions	Q63ZV0, Q9Z113	Gene names	Insm1, Ia1
Domain Architecture	No domain graphic available
Description	Insulinoma-associated protein 1 (Zinc finger protein IA-1).

ADCK1_HUMAN
θ value	1.81305 (rank : 5)	NC score	0.049143 (rank : 3)
Query Neighborhood Hits	17	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	Q86TW2, Q6PD65	Gene names	ADCK1
Domain Architecture	No domain graphic available
Description	Uncharacterized aarF domain-containing protein kinase 1 precursor (EC 2.7.-.-).

4ET_MOUSE
θ value	2.36792 (rank : 6)	NC score	0.034236 (rank : 5)
Query Neighborhood Hits	17	Target Neighborhood Hits	103	Shared Neighborhood Hits	3
SwissProt Accessions	Q9EST3, Q9CSS3	Gene names	Eif4enif1, Clast4
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4E transporter (eIF4E transporter) (4E-T) (Eukaryotic translation initiation factor 4E nuclear import factor 1).

FREM2_HUMAN
θ value	4.03905 (rank : 7)	NC score	0.021959 (rank : 10)
Query Neighborhood Hits	17	Target Neighborhood Hits	76	Shared Neighborhood Hits	4
SwissProt Accessions	Q5SZK8, Q4QQG1, Q5H9N8, Q5T6Q1, Q6N057, Q6ZSB4, Q7Z305, Q7Z341	Gene names	FREM2
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 2 precursor (ECM3 homolog).

FREM3_HUMAN
θ value	4.03905 (rank : 8)	NC score	0.023117 (rank : 9)
Query Neighborhood Hits	17	Target Neighborhood Hits	56	Shared Neighborhood Hits	4
SwissProt Accessions	P0C091	Gene names	FREM3
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 3 precursor.

OSBL1_MOUSE
θ value	5.27518 (rank : 9)	NC score	0.006608 (rank : 15)
Query Neighborhood Hits	17	Target Neighborhood Hits	336	Shared Neighborhood Hits	2
SwissProt Accessions	Q91XL9, O88318, Q3TH97, Q673L8, Q6DFU6	Gene names	Osbpl1a, Orp1, Orp1a
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

ONCM_HUMAN
θ value	6.88961 (rank : 10)	NC score	0.023750 (rank : 8)
Query Neighborhood Hits	17	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	P13725	Gene names	OSM
Domain Architecture
Description	Oncostatin M precursor (OSM).

CCD1A_MOUSE
θ value	8.99809 (rank : 11)	NC score	0.013178 (rank : 12)
Query Neighborhood Hits	17	Target Neighborhood Hits	83	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K1A6, Q2MJB5, Q8R3Z4	Gene names	Cc2d1a
Domain Architecture	No domain graphic available
Description	Coiled-coil and C2 domain-containing protein 1A (Five repressor element under dual repression-binding protein 1) (FRE under dual repression-binding protein 1) (Freud-1).

HXA13_HUMAN
θ value	8.99809 (rank : 12)	NC score	0.006021 (rank : 16)
Query Neighborhood Hits	17	Target Neighborhood Hits	353	Shared Neighborhood Hits	3
SwissProt Accessions	P31271, O43371	Gene names	HOXA13, HOX1J
Domain Architecture
Description	Homeobox protein Hox-A13 (Hox-1J).

HXA13_MOUSE
θ value	8.99809 (rank : 13)	NC score	0.005996 (rank : 17)
Query Neighborhood Hits	17	Target Neighborhood Hits	351	Shared Neighborhood Hits	3
SwissProt Accessions	Q62424	Gene names	Hoxa13, Hox-1.10
Domain Architecture
Description	Homeobox protein Hox-A13 (Hox-1.10).

INSM1_HUMAN
θ value	8.99809 (rank : 14)	NC score	0.009520 (rank : 14)
Query Neighborhood Hits	17	Target Neighborhood Hits	683	Shared Neighborhood Hits	3
SwissProt Accessions	Q01101	Gene names	INSM1, IA1
Domain Architecture	No domain graphic available
Description	Insulinoma-associated protein 1 (Zinc finger protein IA-1).

LRC56_HUMAN
θ value	8.99809 (rank : 15)	NC score	0.012812 (rank : 13)
Query Neighborhood Hits	17	Target Neighborhood Hits	165	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IYG6, Q8N3Q4	Gene names	LRRC56
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 56.

NNTM_HUMAN
θ value	8.99809 (rank : 16)	NC score	0.028861 (rank : 6)
Query Neighborhood Hits	17	Target Neighborhood Hits	17	Shared Neighborhood Hits	4
SwissProt Accessions	Q13423, Q16796, Q8N3V4	Gene names	NNT
Domain Architecture
Description	NAD(P) transhydrogenase, mitochondrial precursor (EC 1.6.1.2) (Pyridine nucleotide transhydrogenase) (Nicotinamide nucleotide transhydrogenase).

NNTM_MOUSE
θ value	8.99809 (rank : 17)	NC score	0.028855 (rank : 7)
Query Neighborhood Hits	17	Target Neighborhood Hits	21	Shared Neighborhood Hits	4
SwissProt Accessions	Q61941, Q9JK70	Gene names	Nnt
Domain Architecture
Description	NAD(P) transhydrogenase, mitochondrial precursor (EC 1.6.1.2) (Pyridine nucleotide transhydrogenase) (Nicotinamide nucleotide transhydrogenase).

Hits sorted by NC score

OPLA_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	17	Target Neighborhood Hits	17	Shared Neighborhood Hits	17
SwissProt Accessions	O14841, Q75W65, Q9Y4Q0	Gene names	OPLAH
Domain Architecture	No domain graphic available
Description	5-oxoprolinase (EC 3.5.2.9) (5-oxo-L-prolinase) (Pyroglutamase) (5- OPase).

OPLA_MOUSE
NC score	0.998751 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	17	Target Neighborhood Hits	14	Shared Neighborhood Hits	9
SwissProt Accessions	Q8K010, Q8R3K2	Gene names	Oplah
Domain Architecture
Description	5-oxoprolinase (EC 3.5.2.9) (5-oxo-L-prolinase) (Pyroglutamase) (5- OPase).

ADCK1_HUMAN
NC score	0.049143 (rank : 3)	θ value	1.81305 (rank : 5)
Query Neighborhood Hits	17	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	Q86TW2, Q6PD65	Gene names	ADCK1
Domain Architecture	No domain graphic available
Description	Uncharacterized aarF domain-containing protein kinase 1 precursor (EC 2.7.-.-).

CI082_HUMAN
NC score	0.041782 (rank : 4)	θ value	1.38821 (rank : 3)
Query Neighborhood Hits	17	Target Neighborhood Hits	32	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H8G2, Q5VY32, Q6IPE6, Q96C59	Gene names	C9orf82
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf82.

4ET_MOUSE
NC score	0.034236 (rank : 5)	θ value	2.36792 (rank : 6)
Query Neighborhood Hits	17	Target Neighborhood Hits	103	Shared Neighborhood Hits	3
SwissProt Accessions	Q9EST3, Q9CSS3	Gene names	Eif4enif1, Clast4
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4E transporter (eIF4E transporter) (4E-T) (Eukaryotic translation initiation factor 4E nuclear import factor 1).

NNTM_HUMAN
NC score	0.028861 (rank : 6)	θ value	8.99809 (rank : 16)
Query Neighborhood Hits	17	Target Neighborhood Hits	17	Shared Neighborhood Hits	4
SwissProt Accessions	Q13423, Q16796, Q8N3V4	Gene names	NNT
Domain Architecture
Description	NAD(P) transhydrogenase, mitochondrial precursor (EC 1.6.1.2) (Pyridine nucleotide transhydrogenase) (Nicotinamide nucleotide transhydrogenase).

NNTM_MOUSE
NC score	0.028855 (rank : 7)	θ value	8.99809 (rank : 17)
Query Neighborhood Hits	17	Target Neighborhood Hits	21	Shared Neighborhood Hits	4
SwissProt Accessions	Q61941, Q9JK70	Gene names	Nnt
Domain Architecture
Description	NAD(P) transhydrogenase, mitochondrial precursor (EC 1.6.1.2) (Pyridine nucleotide transhydrogenase) (Nicotinamide nucleotide transhydrogenase).

ONCM_HUMAN
NC score	0.023750 (rank : 8)	θ value	6.88961 (rank : 10)
Query Neighborhood Hits	17	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	P13725	Gene names	OSM
Domain Architecture
Description	Oncostatin M precursor (OSM).

FREM3_HUMAN
NC score	0.023117 (rank : 9)	θ value	4.03905 (rank : 8)
Query Neighborhood Hits	17	Target Neighborhood Hits	56	Shared Neighborhood Hits	4
SwissProt Accessions	P0C091	Gene names	FREM3
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 3 precursor.

FREM2_HUMAN
NC score	0.021959 (rank : 10)	θ value	4.03905 (rank : 7)
Query Neighborhood Hits	17	Target Neighborhood Hits	76	Shared Neighborhood Hits	4
SwissProt Accessions	Q5SZK8, Q4QQG1, Q5H9N8, Q5T6Q1, Q6N057, Q6ZSB4, Q7Z305, Q7Z341	Gene names	FREM2
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 2 precursor (ECM3 homolog).

INSM1_MOUSE
NC score	0.018448 (rank : 11)	θ value	1.38821 (rank : 4)
Query Neighborhood Hits	17	Target Neighborhood Hits	678	Shared Neighborhood Hits	4
SwissProt Accessions	Q63ZV0, Q9Z113	Gene names	Insm1, Ia1
Domain Architecture	No domain graphic available
Description	Insulinoma-associated protein 1 (Zinc finger protein IA-1).

CCD1A_MOUSE
NC score	0.013178 (rank : 12)	θ value	8.99809 (rank : 11)
Query Neighborhood Hits	17	Target Neighborhood Hits	83	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K1A6, Q2MJB5, Q8R3Z4	Gene names	Cc2d1a
Domain Architecture	No domain graphic available
Description	Coiled-coil and C2 domain-containing protein 1A (Five repressor element under dual repression-binding protein 1) (FRE under dual repression-binding protein 1) (Freud-1).

LRC56_HUMAN
NC score	0.012812 (rank : 13)	θ value	8.99809 (rank : 15)
Query Neighborhood Hits	17	Target Neighborhood Hits	165	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IYG6, Q8N3Q4	Gene names	LRRC56
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 56.

INSM1_HUMAN
NC score	0.009520 (rank : 14)	θ value	8.99809 (rank : 14)
Query Neighborhood Hits	17	Target Neighborhood Hits	683	Shared Neighborhood Hits	3
SwissProt Accessions	Q01101	Gene names	INSM1, IA1
Domain Architecture	No domain graphic available
Description	Insulinoma-associated protein 1 (Zinc finger protein IA-1).

OSBL1_MOUSE
NC score	0.006608 (rank : 15)	θ value	5.27518 (rank : 9)
Query Neighborhood Hits	17	Target Neighborhood Hits	336	Shared Neighborhood Hits	2
SwissProt Accessions	Q91XL9, O88318, Q3TH97, Q673L8, Q6DFU6	Gene names	Osbpl1a, Orp1, Orp1a
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

HXA13_HUMAN
NC score	0.006021 (rank : 16)	θ value	8.99809 (rank : 12)
Query Neighborhood Hits	17	Target Neighborhood Hits	353	Shared Neighborhood Hits	3
SwissProt Accessions	P31271, O43371	Gene names	HOXA13, HOX1J
Domain Architecture
Description	Homeobox protein Hox-A13 (Hox-1J).

HXA13_MOUSE
NC score	0.005996 (rank : 17)	θ value	8.99809 (rank : 13)
Query Neighborhood Hits	17	Target Neighborhood Hits	351	Shared Neighborhood Hits	3
SwissProt Accessions	Q62424	Gene names	Hoxa13, Hox-1.10
Domain Architecture
Description	Homeobox protein Hox-A13 (Hox-1.10).