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Network neighborhood for query Sequence : NAC1_HUMAN

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NAC1_HUMAN
SwissProt Accessions	P32418, O95849, Q9UBL8, Q9UDN1, Q9UDN2, Q9UKX6	Gene names	SLC8A1, CNC, NCX1
Domain Architecture
Description	Sodium/calcium exchanger 1 precursor (Na(+)/Ca(2+)-exchange protein 1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

NAC1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	43	Target Neighborhood Hits	43	Shared Neighborhood Hits	43
SwissProt Accessions	P32418, O95849, Q9UBL8, Q9UDN1, Q9UDN2, Q9UKX6	Gene names	SLC8A1, CNC, NCX1
Domain Architecture
Description	Sodium/calcium exchanger 1 precursor (Na(+)/Ca(2+)-exchange protein 1).

NAC1_MOUSE
θ value	0 (rank : 2)	NC score	0.998566 (rank : 2)
Query Neighborhood Hits	43	Target Neighborhood Hits	41	Shared Neighborhood Hits	34
SwissProt Accessions	P70414	Gene names	Slc8a1, Ncx
Domain Architecture
Description	Sodium/calcium exchanger 1 precursor (Na(+)/Ca(2+)-exchange protein 1).

NAC2_HUMAN
θ value	0 (rank : 3)	NC score	0.992621 (rank : 4)
Query Neighborhood Hits	43	Target Neighborhood Hits	33	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UPR5	Gene names	SLC8A2, KIAA1087, NCX2
Domain Architecture
Description	Sodium/calcium exchanger 2 precursor (Na(+)/Ca(2+)-exchange protein 2).

NAC3_HUMAN
θ value	0 (rank : 4)	NC score	0.993816 (rank : 3)
Query Neighborhood Hits	43	Target Neighborhood Hits	42	Shared Neighborhood Hits	27
SwissProt Accessions	P57103, Q8IUE9, Q8IUF0, Q8NFI7	Gene names	SLC8A3, NCX3
Domain Architecture
Description	Sodium/calcium exchanger 3 precursor (Na(+)/Ca(2+)-exchange protein 3).

GPR98_HUMAN
θ value	6.20254e-17 (rank : 5)	NC score	0.361827 (rank : 17)
Query Neighborhood Hits	43	Target Neighborhood Hits	202	Shared Neighborhood Hits	15
SwissProt Accessions	Q8WXG9, O75171, Q9H0X5, Q9UL61	Gene names	GPR98, KIAA0686, MASS1, VLGR1
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 98 precursor (Monogenic audiogenic seizure susceptibility protein 1 homolog) (Very large G-protein coupled receptor 1) (Usher syndrome type-2C protein).

GPR98_MOUSE
θ value	5.8054e-15 (rank : 6)	NC score	0.357959 (rank : 18)
Query Neighborhood Hits	43	Target Neighborhood Hits	206	Shared Neighborhood Hits	15
SwissProt Accessions	Q8VHN7, Q6ZQ69, Q810D2, Q810D3, Q91ZS0, Q91ZS1	Gene names	Gpr98, Kiaa0686, Mass1, Vlgr1
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 98 precursor (Monogenic audiogenic seizure susceptibility protein 1) (Very large G-protein coupled receptor 1) (Neurepin).

FREM2_MOUSE
θ value	9.26847e-13 (rank : 7)	NC score	0.393624 (rank : 12)
Query Neighborhood Hits	43	Target Neighborhood Hits	73	Shared Neighborhood Hits	15
SwissProt Accessions	Q6NVD0, Q4W2Q5, Q5H8C0, Q811G9, Q8C4G5, Q8CD46	Gene names	Frem2, Nv1
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 2 precursor (ECM3 homolog) (NV domain-containing protein 1).

FRAS1_MOUSE
θ value	2.0648e-12 (rank : 8)	NC score	0.275738 (rank : 20)
Query Neighborhood Hits	43	Target Neighborhood Hits	747	Shared Neighborhood Hits	15
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

FREM2_HUMAN
θ value	4.59992e-12 (rank : 9)	NC score	0.389328 (rank : 14)
Query Neighborhood Hits	43	Target Neighborhood Hits	76	Shared Neighborhood Hits	16
SwissProt Accessions	Q5SZK8, Q4QQG1, Q5H9N8, Q5T6Q1, Q6N057, Q6ZSB4, Q7Z305, Q7Z341	Gene names	FREM2
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 2 precursor (ECM3 homolog).

FRAS1_HUMAN
θ value	1.33837e-11 (rank : 10)	NC score	0.271483 (rank : 22)
Query Neighborhood Hits	43	Target Neighborhood Hits	759	Shared Neighborhood Hits	16
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

NCKX3_MOUSE
θ value	6.64225e-11 (rank : 11)	NC score	0.427844 (rank : 8)
Query Neighborhood Hits	43	Target Neighborhood Hits	30	Shared Neighborhood Hits	14
SwissProt Accessions	Q99PD7, Q99JR2, Q99PD8	Gene names	Slc24a3, Nckx3
Domain Architecture
Description	Sodium/potassium/calcium exchanger 3 precursor (Na(+)/K(+)/Ca(2+)- exchange protein 3).

FREM3_HUMAN
θ value	8.67504e-11 (rank : 12)	NC score	0.386870 (rank : 15)
Query Neighborhood Hits	43	Target Neighborhood Hits	56	Shared Neighborhood Hits	15
SwissProt Accessions	P0C091	Gene names	FREM3
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 3 precursor.

NCKX4_HUMAN
θ value	1.47974e-10 (rank : 13)	NC score	0.426325 (rank : 9)
Query Neighborhood Hits	43	Target Neighborhood Hits	24	Shared Neighborhood Hits	14
SwissProt Accessions	Q8NFF2, Q8N8U6, Q8NCX1, Q8NFF0, Q8NFF1	Gene names	SLC24A4, NCKX4
Domain Architecture
Description	Sodium/potassium/calcium exchanger 4 precursor (Na(+)/K(+)/Ca(2+)- exchange protein 4) (Solute carrier family 24 member 4).

NCKX3_HUMAN
θ value	2.52405e-10 (rank : 14)	NC score	0.426020 (rank : 10)
Query Neighborhood Hits	43	Target Neighborhood Hits	20	Shared Neighborhood Hits	14
SwissProt Accessions	Q9HC58, Q9BQJ9, Q9BQL7, Q9BQY3, Q9H519	Gene names	SLC24A3, NCKX3
Domain Architecture
Description	Sodium/potassium/calcium exchanger 3 precursor (Na(+)/K(+)/Ca(2+)- exchange protein 3) (Solute carrier family 24 member 3).

NCKX4_MOUSE
θ value	2.52405e-10 (rank : 15)	NC score	0.425860 (rank : 11)
Query Neighborhood Hits	43	Target Neighborhood Hits	22	Shared Neighborhood Hits	14
SwissProt Accessions	Q8CGQ8, Q8BLL5, Q8BLL7	Gene names	Slc24a4, Nckx4
Domain Architecture
Description	Sodium/potassium/calcium exchanger 4 precursor (Na(+)/K(+)/Ca(2+)- exchange protein 4).

FREM3_MOUSE
θ value	4.30538e-10 (rank : 16)	NC score	0.392581 (rank : 13)
Query Neighborhood Hits	43	Target Neighborhood Hits	49	Shared Neighborhood Hits	15
SwissProt Accessions	Q5H8B9	Gene names	Frem3, Nv2
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 3 precursor (NV domain- containing protein 2).

NCKX5_HUMAN
θ value	5.62301e-10 (rank : 17)	NC score	0.451144 (rank : 5)
Query Neighborhood Hits	43	Target Neighborhood Hits	16	Shared Neighborhood Hits	14
SwissProt Accessions	Q71RS6, Q6DKH3	Gene names	SLC24A5, JSX, NCKX5
Domain Architecture	No domain graphic available
Description	Sodium/potassium/calcium exchanger 5 precursor (Na(+)/K(+)/Ca(2+)- exchange protein 5) (Solute carrier family 24 member 5).

NCKX2_HUMAN
θ value	1.80886e-08 (rank : 18)	NC score	0.442915 (rank : 6)
Query Neighborhood Hits	43	Target Neighborhood Hits	34	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UI40, Q9NTN5, Q9NZQ4	Gene names	SLC24A2, NCKX2
Domain Architecture
Description	Sodium/potassium/calcium exchanger 2 precursor (Na(+)/K(+)/Ca(2+)- exchange protein 2) (Retinal cone Na-Ca+K exchanger) (Solute carrier family 24 member 2).

NCKX5_MOUSE
θ value	2.36244e-08 (rank : 19)	NC score	0.434957 (rank : 7)
Query Neighborhood Hits	43	Target Neighborhood Hits	15	Shared Neighborhood Hits	14
SwissProt Accessions	Q8C261, Q6XE39, Q8CJF1	Gene names	Slc24a5, Nckx5
Domain Architecture	No domain graphic available
Description	Sodium/potassium/calcium exchanger 5 precursor (Na(+)/K(+)/Ca(2+)- exchange protein 5) (Solute carrier family 24 member 5).

NCKX1_HUMAN
θ value	3.77169e-06 (rank : 20)	NC score	0.371674 (rank : 16)
Query Neighborhood Hits	43	Target Neighborhood Hits	223	Shared Neighborhood Hits	14
SwissProt Accessions	O60721, O43485, O75184	Gene names	SLC24A1, KIAA0702, NCKX1
Domain Architecture
Description	Sodium/potassium/calcium exchanger 1 (Na(+)/K(+)/Ca(2+)-exchange protein 1) (Retinal rod Na-Ca+K exchanger).

ITB4_HUMAN
θ value	9.29e-05 (rank : 21)	NC score	0.109424 (rank : 27)
Query Neighborhood Hits	43	Target Neighborhood Hits	458	Shared Neighborhood Hits	13
SwissProt Accessions	P16144, O14690, O14691, O15339, O15340, O15341, Q9UIQ4	Gene names	ITGB4
Domain Architecture
Description	Integrin beta-4 precursor (GP150) (CD104 antigen).

FREM1_HUMAN
θ value	0.00020696 (rank : 22)	NC score	0.278851 (rank : 19)
Query Neighborhood Hits	43	Target Neighborhood Hits	170	Shared Neighborhood Hits	14
SwissProt Accessions	Q5H8C1, Q5VV00, Q5VV01, Q6MZI4, Q8NEG9, Q96LI3	Gene names	FREM1, C9orf154
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 1 precursor (Protein QBRICK).

FREM1_MOUSE
θ value	0.000786445 (rank : 23)	NC score	0.274927 (rank : 21)
Query Neighborhood Hits	43	Target Neighborhood Hits	163	Shared Neighborhood Hits	15
SwissProt Accessions	Q684R7, Q5H8C2, Q5M7B3, Q8C732	Gene names	Frem1
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 1 precursor (Protein QBRICK).

NCKX6_HUMAN
θ value	0.0736092 (rank : 24)	NC score	0.220571 (rank : 23)
Query Neighborhood Hits	43	Target Neighborhood Hits	20	Shared Neighborhood Hits	14
SwissProt Accessions	Q6J4K2, Q4KMS9, Q6J4K1, Q9H6I8	Gene names	SLC24A6, NCKX6, NCLX
Domain Architecture	No domain graphic available
Description	Sodium/potassium/calcium exchanger 6 precursor (Na(+)/K(+)/Ca(2+)- exchange protein 6) (Solute carrier family 24 member 6).

NCKX6_MOUSE
θ value	0.163984 (rank : 25)	NC score	0.217496 (rank : 24)
Query Neighborhood Hits	43	Target Neighborhood Hits	18	Shared Neighborhood Hits	14
SwissProt Accessions	Q925Q3, Q3U067, Q80XM7	Gene names	Slc24a6, Nckx6
Domain Architecture	No domain graphic available
Description	Sodium/potassium/calcium exchanger 6 precursor (Na(+)/K(+)/Ca(2+)- exchange protein 6) (Solute carrier family 24 member 6).

AFAD_HUMAN
θ value	0.813845 (rank : 26)	NC score	0.020325 (rank : 32)
Query Neighborhood Hits	43	Target Neighborhood Hits	689	Shared Neighborhood Hits	5
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

KIF3B_HUMAN
θ value	1.06291 (rank : 27)	NC score	0.009451 (rank : 36)
Query Neighborhood Hits	43	Target Neighborhood Hits	540	Shared Neighborhood Hits	5
SwissProt Accessions	O15066	Gene names	KIF3B, KIAA0359
Domain Architecture
Description	Kinesin-like protein KIF3B (Microtubule plus end-directed kinesin motor 3B) (HH0048).

CSMD2_HUMAN
θ value	2.36792 (rank : 28)	NC score	0.006884 (rank : 41)
Query Neighborhood Hits	43	Target Neighborhood Hits	188	Shared Neighborhood Hits	3
SwissProt Accessions	Q7Z408, Q5VT59, Q8N963, Q96Q03, Q9H4V7, Q9H4V8, Q9H4V9, Q9H4W0, Q9H4W1, Q9H4W2, Q9H4W3, Q9H4W4, Q9HCY5, Q9HCY6, Q9HCY7	Gene names	CSMD2, KIAA1884
Domain Architecture
Description	CUB and sushi domain-containing protein 2 (CUB and sushi multiple domains protein 2).

KIF3B_MOUSE
θ value	2.36792 (rank : 29)	NC score	0.008578 (rank : 39)
Query Neighborhood Hits	43	Target Neighborhood Hits	533	Shared Neighborhood Hits	5
SwissProt Accessions	Q61771	Gene names	Kif3b
Domain Architecture
Description	Kinesin-like protein KIF3B (Microtubule plus end-directed kinesin motor 3B).

TM9S1_HUMAN
θ value	3.0926 (rank : 30)	NC score	0.025639 (rank : 30)
Query Neighborhood Hits	43	Target Neighborhood Hits	17	Shared Neighborhood Hits	4
SwissProt Accessions	O15321, Q96FI8	Gene names	TM9SF1
Domain Architecture
Description	Transmembrane 9 superfamily protein member 1 precursor (hMP70).

TM9S1_MOUSE
θ value	3.0926 (rank : 31)	NC score	0.025708 (rank : 29)
Query Neighborhood Hits	43	Target Neighborhood Hits	17	Shared Neighborhood Hits	4
SwissProt Accessions	Q9DBU0, Q3U7S4, Q8VD27, Q922J5, Q9ET29	Gene names	Tm9sf1
Domain Architecture
Description	Transmembrane 9 superfamily protein member 1 precursor.

PZP_HUMAN
θ value	4.03905 (rank : 32)	NC score	0.008261 (rank : 40)
Query Neighborhood Hits	43	Target Neighborhood Hits	36	Shared Neighborhood Hits	2
SwissProt Accessions	P20742, Q15273	Gene names	PZP
Domain Architecture
Description	Pregnancy zone protein precursor.

SRCH_HUMAN
θ value	5.27518 (rank : 33)	NC score	0.026591 (rank : 28)
Query Neighborhood Hits	43	Target Neighborhood Hits	225	Shared Neighborhood Hits	5
SwissProt Accessions	P23327, Q504Y6	Gene names	HRC, HCP
Domain Architecture	No domain graphic available
Description	Sarcoplasmic reticulum histidine-rich calcium-binding protein precursor.

GLE1_MOUSE
θ value	6.88961 (rank : 34)	NC score	0.017313 (rank : 33)
Query Neighborhood Hits	43	Target Neighborhood Hits	504	Shared Neighborhood Hits	6
SwissProt Accessions	Q8R322, Q3TT10, Q3TU23, Q3UD65, Q8BT16, Q9D4A6	Gene names	Gle1l
Domain Architecture	No domain graphic available
Description	Nucleoporin GLE1 (GLE1-like protein).

HM20A_HUMAN
θ value	6.88961 (rank : 35)	NC score	0.009089 (rank : 37)
Query Neighborhood Hits	43	Target Neighborhood Hits	343	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NP66, Q53G31, Q9NSF6	Gene names	HMG20A, HMGX1
Domain Architecture	No domain graphic available
Description	High mobility group protein 20A (HMG box-containing protein 20A) (HMG domain-containing protein HMGX1).

HM20A_MOUSE
θ value	6.88961 (rank : 36)	NC score	0.009030 (rank : 38)
Query Neighborhood Hits	43	Target Neighborhood Hits	348	Shared Neighborhood Hits	4
SwissProt Accessions	Q9DC33, Q3LSF9, Q6NV87, Q8BSK1, Q8C3C1, Q8CAA0, Q9CYG2	Gene names	Hmg20a, Ibraf
Domain Architecture	No domain graphic available
Description	High mobility group protein 20A (HMG box-containing protein 20A) (iBRAF) (Inhibitor of BRAF35) (HMG domain protein HMGX1).

KINH_HUMAN
θ value	6.88961 (rank : 37)	NC score	0.005503 (rank : 43)
Query Neighborhood Hits	43	Target Neighborhood Hits	1231	Shared Neighborhood Hits	9
SwissProt Accessions	P33176, Q5VZ85	Gene names	KIF5B, KNS, KNS1
Domain Architecture
Description	Kinesin heavy chain (Ubiquitous kinesin heavy chain) (UKHC).

ADCY3_HUMAN
θ value	8.99809 (rank : 38)	NC score	0.006362 (rank : 42)
Query Neighborhood Hits	43	Target Neighborhood Hits	58	Shared Neighborhood Hits	3
SwissProt Accessions	O60266, Q9UDB1	Gene names	ADCY3, KIAA0511
Domain Architecture
Description	Adenylate cyclase type 3 (EC 4.6.1.1) (Adenylate cyclase type III) (Adenylate cyclase, olfactive type) (ATP pyrophosphate-lyase 3) (Adenylyl cyclase 3) (AC-III) (AC3).

BHLH2_MOUSE
θ value	8.99809 (rank : 39)	NC score	0.013934 (rank : 34)
Query Neighborhood Hits	43	Target Neighborhood Hits	70	Shared Neighborhood Hits	3
SwissProt Accessions	O35185, P97289	Gene names	Bhlhb2, Clast5, Stra13
Domain Architecture
Description	Class B basic helix-loop-helix protein 2 (bHLHB2) (Stimulated with retinoic acid 13) (E47 interaction protein 1) (eipl).

CTNA3_HUMAN
θ value	8.99809 (rank : 40)	NC score	0.004992 (rank : 44)
Query Neighborhood Hits	43	Target Neighborhood Hits	71	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UI47, Q5VSR2, Q6P056	Gene names	CTNNA3
Domain Architecture	No domain graphic available
Description	Catenin alpha-3 (Alpha T-catenin) (Cadherin-associated protein).

GLE1_HUMAN
θ value	8.99809 (rank : 41)	NC score	0.021010 (rank : 31)
Query Neighborhood Hits	43	Target Neighborhood Hits	445	Shared Neighborhood Hits	9
SwissProt Accessions	Q53GS7, O75458, Q53GT9, Q5VVU1, Q8NCP6, Q9UFL6	Gene names	GLE1L, GLE1
Domain Architecture	No domain graphic available
Description	Nucleoporin GLE1 (GLE1-like protein) (hGLE1).

KTN1_HUMAN
θ value	8.99809 (rank : 42)	NC score	0.003124 (rank : 45)
Query Neighborhood Hits	43	Target Neighborhood Hits	1197	Shared Neighborhood Hits	10
SwissProt Accessions	Q86UP2, Q13999, Q14707, Q15387, Q86W57	Gene names	KTN1, CG1, KIAA0004
Domain Architecture	No domain graphic available
Description	Kinectin (Kinesin receptor) (CG-1 antigen).

SART3_MOUSE
θ value	8.99809 (rank : 43)	NC score	0.009484 (rank : 35)
Query Neighborhood Hits	43	Target Neighborhood Hits	341	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JLI8, Q6ZQI2, Q8BPK9, Q8C3B7, Q8CFU9	Gene names	Sart3, Kiaa0156
Domain Architecture	No domain graphic available
Description	Squamous cell carcinoma antigen recognized by T-cells 3 (SART-3) (mSART-3) (Tumor-rejection antigen SART3).

CSPG4_HUMAN
θ value	θ > 10 (rank : 44)	NC score	0.146191 (rank : 25)
Query Neighborhood Hits	43	Target Neighborhood Hits	112	Shared Neighborhood Hits	8
SwissProt Accessions	Q6UVK1, Q92675	Gene names	CSPG4, MCSP
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 4 precursor (Chondroitin sulfate proteoglycan NG2) (Melanoma chondroitin sulfate proteoglycan) (Melanoma-associated chondroitin sulfate proteoglycan).

CSPG4_MOUSE
θ value	θ > 10 (rank : 45)	NC score	0.142644 (rank : 26)
Query Neighborhood Hits	43	Target Neighborhood Hits	105	Shared Neighborhood Hits	8
SwissProt Accessions	Q8VHY0, Q5DTG1, Q8BPI8, Q8CE79	Gene names	Cspg4, An2, Kiaa4232, Ng2
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 4 precursor (Chondroitin sulfate proteoglycan NG2) (AN2 proteoglycan).

Hits sorted by NC score

NAC1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	43	Target Neighborhood Hits	43	Shared Neighborhood Hits	43
SwissProt Accessions	P32418, O95849, Q9UBL8, Q9UDN1, Q9UDN2, Q9UKX6	Gene names	SLC8A1, CNC, NCX1
Domain Architecture
Description	Sodium/calcium exchanger 1 precursor (Na(+)/Ca(2+)-exchange protein 1).

NAC1_MOUSE
NC score	0.998566 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	43	Target Neighborhood Hits	41	Shared Neighborhood Hits	34
SwissProt Accessions	P70414	Gene names	Slc8a1, Ncx
Domain Architecture
Description	Sodium/calcium exchanger 1 precursor (Na(+)/Ca(2+)-exchange protein 1).

NAC3_HUMAN
NC score	0.993816 (rank : 3)	θ value	0 (rank : 4)
Query Neighborhood Hits	43	Target Neighborhood Hits	42	Shared Neighborhood Hits	27
SwissProt Accessions	P57103, Q8IUE9, Q8IUF0, Q8NFI7	Gene names	SLC8A3, NCX3
Domain Architecture
Description	Sodium/calcium exchanger 3 precursor (Na(+)/Ca(2+)-exchange protein 3).

NAC2_HUMAN
NC score	0.992621 (rank : 4)	θ value	0 (rank : 3)
Query Neighborhood Hits	43	Target Neighborhood Hits	33	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UPR5	Gene names	SLC8A2, KIAA1087, NCX2
Domain Architecture
Description	Sodium/calcium exchanger 2 precursor (Na(+)/Ca(2+)-exchange protein 2).

NCKX5_HUMAN
NC score	0.451144 (rank : 5)	θ value	5.62301e-10 (rank : 17)
Query Neighborhood Hits	43	Target Neighborhood Hits	16	Shared Neighborhood Hits	14
SwissProt Accessions	Q71RS6, Q6DKH3	Gene names	SLC24A5, JSX, NCKX5
Domain Architecture	No domain graphic available
Description	Sodium/potassium/calcium exchanger 5 precursor (Na(+)/K(+)/Ca(2+)- exchange protein 5) (Solute carrier family 24 member 5).

NCKX2_HUMAN
NC score	0.442915 (rank : 6)	θ value	1.80886e-08 (rank : 18)
Query Neighborhood Hits	43	Target Neighborhood Hits	34	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UI40, Q9NTN5, Q9NZQ4	Gene names	SLC24A2, NCKX2
Domain Architecture
Description	Sodium/potassium/calcium exchanger 2 precursor (Na(+)/K(+)/Ca(2+)- exchange protein 2) (Retinal cone Na-Ca+K exchanger) (Solute carrier family 24 member 2).

NCKX5_MOUSE
NC score	0.434957 (rank : 7)	θ value	2.36244e-08 (rank : 19)
Query Neighborhood Hits	43	Target Neighborhood Hits	15	Shared Neighborhood Hits	14
SwissProt Accessions	Q8C261, Q6XE39, Q8CJF1	Gene names	Slc24a5, Nckx5
Domain Architecture	No domain graphic available
Description	Sodium/potassium/calcium exchanger 5 precursor (Na(+)/K(+)/Ca(2+)- exchange protein 5) (Solute carrier family 24 member 5).

NCKX3_MOUSE
NC score	0.427844 (rank : 8)	θ value	6.64225e-11 (rank : 11)
Query Neighborhood Hits	43	Target Neighborhood Hits	30	Shared Neighborhood Hits	14
SwissProt Accessions	Q99PD7, Q99JR2, Q99PD8	Gene names	Slc24a3, Nckx3
Domain Architecture
Description	Sodium/potassium/calcium exchanger 3 precursor (Na(+)/K(+)/Ca(2+)- exchange protein 3).

NCKX4_HUMAN
NC score	0.426325 (rank : 9)	θ value	1.47974e-10 (rank : 13)
Query Neighborhood Hits	43	Target Neighborhood Hits	24	Shared Neighborhood Hits	14
SwissProt Accessions	Q8NFF2, Q8N8U6, Q8NCX1, Q8NFF0, Q8NFF1	Gene names	SLC24A4, NCKX4
Domain Architecture
Description	Sodium/potassium/calcium exchanger 4 precursor (Na(+)/K(+)/Ca(2+)- exchange protein 4) (Solute carrier family 24 member 4).

NCKX3_HUMAN
NC score	0.426020 (rank : 10)	θ value	2.52405e-10 (rank : 14)
Query Neighborhood Hits	43	Target Neighborhood Hits	20	Shared Neighborhood Hits	14
SwissProt Accessions	Q9HC58, Q9BQJ9, Q9BQL7, Q9BQY3, Q9H519	Gene names	SLC24A3, NCKX3
Domain Architecture
Description	Sodium/potassium/calcium exchanger 3 precursor (Na(+)/K(+)/Ca(2+)- exchange protein 3) (Solute carrier family 24 member 3).

NCKX4_MOUSE
NC score	0.425860 (rank : 11)	θ value	2.52405e-10 (rank : 15)
Query Neighborhood Hits	43	Target Neighborhood Hits	22	Shared Neighborhood Hits	14
SwissProt Accessions	Q8CGQ8, Q8BLL5, Q8BLL7	Gene names	Slc24a4, Nckx4
Domain Architecture
Description	Sodium/potassium/calcium exchanger 4 precursor (Na(+)/K(+)/Ca(2+)- exchange protein 4).

FREM2_MOUSE
NC score	0.393624 (rank : 12)	θ value	9.26847e-13 (rank : 7)
Query Neighborhood Hits	43	Target Neighborhood Hits	73	Shared Neighborhood Hits	15
SwissProt Accessions	Q6NVD0, Q4W2Q5, Q5H8C0, Q811G9, Q8C4G5, Q8CD46	Gene names	Frem2, Nv1
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 2 precursor (ECM3 homolog) (NV domain-containing protein 1).

FREM3_MOUSE
NC score	0.392581 (rank : 13)	θ value	4.30538e-10 (rank : 16)
Query Neighborhood Hits	43	Target Neighborhood Hits	49	Shared Neighborhood Hits	15
SwissProt Accessions	Q5H8B9	Gene names	Frem3, Nv2
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 3 precursor (NV domain- containing protein 2).

FREM2_HUMAN
NC score	0.389328 (rank : 14)	θ value	4.59992e-12 (rank : 9)
Query Neighborhood Hits	43	Target Neighborhood Hits	76	Shared Neighborhood Hits	16
SwissProt Accessions	Q5SZK8, Q4QQG1, Q5H9N8, Q5T6Q1, Q6N057, Q6ZSB4, Q7Z305, Q7Z341	Gene names	FREM2
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 2 precursor (ECM3 homolog).

FREM3_HUMAN
NC score	0.386870 (rank : 15)	θ value	8.67504e-11 (rank : 12)
Query Neighborhood Hits	43	Target Neighborhood Hits	56	Shared Neighborhood Hits	15
SwissProt Accessions	P0C091	Gene names	FREM3
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 3 precursor.

NCKX1_HUMAN
NC score	0.371674 (rank : 16)	θ value	3.77169e-06 (rank : 20)
Query Neighborhood Hits	43	Target Neighborhood Hits	223	Shared Neighborhood Hits	14
SwissProt Accessions	O60721, O43485, O75184	Gene names	SLC24A1, KIAA0702, NCKX1
Domain Architecture
Description	Sodium/potassium/calcium exchanger 1 (Na(+)/K(+)/Ca(2+)-exchange protein 1) (Retinal rod Na-Ca+K exchanger).

GPR98_HUMAN
NC score	0.361827 (rank : 17)	θ value	6.20254e-17 (rank : 5)
Query Neighborhood Hits	43	Target Neighborhood Hits	202	Shared Neighborhood Hits	15
SwissProt Accessions	Q8WXG9, O75171, Q9H0X5, Q9UL61	Gene names	GPR98, KIAA0686, MASS1, VLGR1
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 98 precursor (Monogenic audiogenic seizure susceptibility protein 1 homolog) (Very large G-protein coupled receptor 1) (Usher syndrome type-2C protein).

GPR98_MOUSE
NC score	0.357959 (rank : 18)	θ value	5.8054e-15 (rank : 6)
Query Neighborhood Hits	43	Target Neighborhood Hits	206	Shared Neighborhood Hits	15
SwissProt Accessions	Q8VHN7, Q6ZQ69, Q810D2, Q810D3, Q91ZS0, Q91ZS1	Gene names	Gpr98, Kiaa0686, Mass1, Vlgr1
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 98 precursor (Monogenic audiogenic seizure susceptibility protein 1) (Very large G-protein coupled receptor 1) (Neurepin).

FREM1_HUMAN
NC score	0.278851 (rank : 19)	θ value	0.00020696 (rank : 22)
Query Neighborhood Hits	43	Target Neighborhood Hits	170	Shared Neighborhood Hits	14
SwissProt Accessions	Q5H8C1, Q5VV00, Q5VV01, Q6MZI4, Q8NEG9, Q96LI3	Gene names	FREM1, C9orf154
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 1 precursor (Protein QBRICK).

FRAS1_MOUSE
NC score	0.275738 (rank : 20)	θ value	2.0648e-12 (rank : 8)
Query Neighborhood Hits	43	Target Neighborhood Hits	747	Shared Neighborhood Hits	15
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

FREM1_MOUSE
NC score	0.274927 (rank : 21)	θ value	0.000786445 (rank : 23)
Query Neighborhood Hits	43	Target Neighborhood Hits	163	Shared Neighborhood Hits	15
SwissProt Accessions	Q684R7, Q5H8C2, Q5M7B3, Q8C732	Gene names	Frem1
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 1 precursor (Protein QBRICK).

FRAS1_HUMAN
NC score	0.271483 (rank : 22)	θ value	1.33837e-11 (rank : 10)
Query Neighborhood Hits	43	Target Neighborhood Hits	759	Shared Neighborhood Hits	16
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

NCKX6_HUMAN
NC score	0.220571 (rank : 23)	θ value	0.0736092 (rank : 24)
Query Neighborhood Hits	43	Target Neighborhood Hits	20	Shared Neighborhood Hits	14
SwissProt Accessions	Q6J4K2, Q4KMS9, Q6J4K1, Q9H6I8	Gene names	SLC24A6, NCKX6, NCLX
Domain Architecture	No domain graphic available
Description	Sodium/potassium/calcium exchanger 6 precursor (Na(+)/K(+)/Ca(2+)- exchange protein 6) (Solute carrier family 24 member 6).

NCKX6_MOUSE
NC score	0.217496 (rank : 24)	θ value	0.163984 (rank : 25)
Query Neighborhood Hits	43	Target Neighborhood Hits	18	Shared Neighborhood Hits	14
SwissProt Accessions	Q925Q3, Q3U067, Q80XM7	Gene names	Slc24a6, Nckx6
Domain Architecture	No domain graphic available
Description	Sodium/potassium/calcium exchanger 6 precursor (Na(+)/K(+)/Ca(2+)- exchange protein 6) (Solute carrier family 24 member 6).

CSPG4_HUMAN
NC score	0.146191 (rank : 25)	θ value	θ > 10 (rank : 44)
Query Neighborhood Hits	43	Target Neighborhood Hits	112	Shared Neighborhood Hits	8
SwissProt Accessions	Q6UVK1, Q92675	Gene names	CSPG4, MCSP
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 4 precursor (Chondroitin sulfate proteoglycan NG2) (Melanoma chondroitin sulfate proteoglycan) (Melanoma-associated chondroitin sulfate proteoglycan).

CSPG4_MOUSE
NC score	0.142644 (rank : 26)	θ value	θ > 10 (rank : 45)
Query Neighborhood Hits	43	Target Neighborhood Hits	105	Shared Neighborhood Hits	8
SwissProt Accessions	Q8VHY0, Q5DTG1, Q8BPI8, Q8CE79	Gene names	Cspg4, An2, Kiaa4232, Ng2
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 4 precursor (Chondroitin sulfate proteoglycan NG2) (AN2 proteoglycan).

ITB4_HUMAN
NC score	0.109424 (rank : 27)	θ value	9.29e-05 (rank : 21)
Query Neighborhood Hits	43	Target Neighborhood Hits	458	Shared Neighborhood Hits	13
SwissProt Accessions	P16144, O14690, O14691, O15339, O15340, O15341, Q9UIQ4	Gene names	ITGB4
Domain Architecture
Description	Integrin beta-4 precursor (GP150) (CD104 antigen).

SRCH_HUMAN
NC score	0.026591 (rank : 28)	θ value	5.27518 (rank : 33)
Query Neighborhood Hits	43	Target Neighborhood Hits	225	Shared Neighborhood Hits	5
SwissProt Accessions	P23327, Q504Y6	Gene names	HRC, HCP
Domain Architecture	No domain graphic available
Description	Sarcoplasmic reticulum histidine-rich calcium-binding protein precursor.

TM9S1_MOUSE
NC score	0.025708 (rank : 29)	θ value	3.0926 (rank : 31)
Query Neighborhood Hits	43	Target Neighborhood Hits	17	Shared Neighborhood Hits	4
SwissProt Accessions	Q9DBU0, Q3U7S4, Q8VD27, Q922J5, Q9ET29	Gene names	Tm9sf1
Domain Architecture
Description	Transmembrane 9 superfamily protein member 1 precursor.

TM9S1_HUMAN
NC score	0.025639 (rank : 30)	θ value	3.0926 (rank : 30)
Query Neighborhood Hits	43	Target Neighborhood Hits	17	Shared Neighborhood Hits	4
SwissProt Accessions	O15321, Q96FI8	Gene names	TM9SF1
Domain Architecture
Description	Transmembrane 9 superfamily protein member 1 precursor (hMP70).

GLE1_HUMAN
NC score	0.021010 (rank : 31)	θ value	8.99809 (rank : 41)
Query Neighborhood Hits	43	Target Neighborhood Hits	445	Shared Neighborhood Hits	9
SwissProt Accessions	Q53GS7, O75458, Q53GT9, Q5VVU1, Q8NCP6, Q9UFL6	Gene names	GLE1L, GLE1
Domain Architecture	No domain graphic available
Description	Nucleoporin GLE1 (GLE1-like protein) (hGLE1).

AFAD_HUMAN
NC score	0.020325 (rank : 32)	θ value	0.813845 (rank : 26)
Query Neighborhood Hits	43	Target Neighborhood Hits	689	Shared Neighborhood Hits	5
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

GLE1_MOUSE
NC score	0.017313 (rank : 33)	θ value	6.88961 (rank : 34)
Query Neighborhood Hits	43	Target Neighborhood Hits	504	Shared Neighborhood Hits	6
SwissProt Accessions	Q8R322, Q3TT10, Q3TU23, Q3UD65, Q8BT16, Q9D4A6	Gene names	Gle1l
Domain Architecture	No domain graphic available
Description	Nucleoporin GLE1 (GLE1-like protein).

BHLH2_MOUSE
NC score	0.013934 (rank : 34)	θ value	8.99809 (rank : 39)
Query Neighborhood Hits	43	Target Neighborhood Hits	70	Shared Neighborhood Hits	3
SwissProt Accessions	O35185, P97289	Gene names	Bhlhb2, Clast5, Stra13
Domain Architecture
Description	Class B basic helix-loop-helix protein 2 (bHLHB2) (Stimulated with retinoic acid 13) (E47 interaction protein 1) (eipl).

SART3_MOUSE
NC score	0.009484 (rank : 35)	θ value	8.99809 (rank : 43)
Query Neighborhood Hits	43	Target Neighborhood Hits	341	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JLI8, Q6ZQI2, Q8BPK9, Q8C3B7, Q8CFU9	Gene names	Sart3, Kiaa0156
Domain Architecture	No domain graphic available
Description	Squamous cell carcinoma antigen recognized by T-cells 3 (SART-3) (mSART-3) (Tumor-rejection antigen SART3).

KIF3B_HUMAN
NC score	0.009451 (rank : 36)	θ value	1.06291 (rank : 27)
Query Neighborhood Hits	43	Target Neighborhood Hits	540	Shared Neighborhood Hits	5
SwissProt Accessions	O15066	Gene names	KIF3B, KIAA0359
Domain Architecture
Description	Kinesin-like protein KIF3B (Microtubule plus end-directed kinesin motor 3B) (HH0048).

HM20A_HUMAN
NC score	0.009089 (rank : 37)	θ value	6.88961 (rank : 35)
Query Neighborhood Hits	43	Target Neighborhood Hits	343	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NP66, Q53G31, Q9NSF6	Gene names	HMG20A, HMGX1
Domain Architecture	No domain graphic available
Description	High mobility group protein 20A (HMG box-containing protein 20A) (HMG domain-containing protein HMGX1).

HM20A_MOUSE
NC score	0.009030 (rank : 38)	θ value	6.88961 (rank : 36)
Query Neighborhood Hits	43	Target Neighborhood Hits	348	Shared Neighborhood Hits	4
SwissProt Accessions	Q9DC33, Q3LSF9, Q6NV87, Q8BSK1, Q8C3C1, Q8CAA0, Q9CYG2	Gene names	Hmg20a, Ibraf
Domain Architecture	No domain graphic available
Description	High mobility group protein 20A (HMG box-containing protein 20A) (iBRAF) (Inhibitor of BRAF35) (HMG domain protein HMGX1).

KIF3B_MOUSE
NC score	0.008578 (rank : 39)	θ value	2.36792 (rank : 29)
Query Neighborhood Hits	43	Target Neighborhood Hits	533	Shared Neighborhood Hits	5
SwissProt Accessions	Q61771	Gene names	Kif3b
Domain Architecture
Description	Kinesin-like protein KIF3B (Microtubule plus end-directed kinesin motor 3B).

PZP_HUMAN
NC score	0.008261 (rank : 40)	θ value	4.03905 (rank : 32)
Query Neighborhood Hits	43	Target Neighborhood Hits	36	Shared Neighborhood Hits	2
SwissProt Accessions	P20742, Q15273	Gene names	PZP
Domain Architecture
Description	Pregnancy zone protein precursor.

CSMD2_HUMAN
NC score	0.006884 (rank : 41)	θ value	2.36792 (rank : 28)
Query Neighborhood Hits	43	Target Neighborhood Hits	188	Shared Neighborhood Hits	3
SwissProt Accessions	Q7Z408, Q5VT59, Q8N963, Q96Q03, Q9H4V7, Q9H4V8, Q9H4V9, Q9H4W0, Q9H4W1, Q9H4W2, Q9H4W3, Q9H4W4, Q9HCY5, Q9HCY6, Q9HCY7	Gene names	CSMD2, KIAA1884
Domain Architecture
Description	CUB and sushi domain-containing protein 2 (CUB and sushi multiple domains protein 2).

ADCY3_HUMAN
NC score	0.006362 (rank : 42)	θ value	8.99809 (rank : 38)
Query Neighborhood Hits	43	Target Neighborhood Hits	58	Shared Neighborhood Hits	3
SwissProt Accessions	O60266, Q9UDB1	Gene names	ADCY3, KIAA0511
Domain Architecture
Description	Adenylate cyclase type 3 (EC 4.6.1.1) (Adenylate cyclase type III) (Adenylate cyclase, olfactive type) (ATP pyrophosphate-lyase 3) (Adenylyl cyclase 3) (AC-III) (AC3).

KINH_HUMAN
NC score	0.005503 (rank : 43)	θ value	6.88961 (rank : 37)
Query Neighborhood Hits	43	Target Neighborhood Hits	1231	Shared Neighborhood Hits	9
SwissProt Accessions	P33176, Q5VZ85	Gene names	KIF5B, KNS, KNS1
Domain Architecture
Description	Kinesin heavy chain (Ubiquitous kinesin heavy chain) (UKHC).

CTNA3_HUMAN
NC score	0.004992 (rank : 44)	θ value	8.99809 (rank : 40)
Query Neighborhood Hits	43	Target Neighborhood Hits	71	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UI47, Q5VSR2, Q6P056	Gene names	CTNNA3
Domain Architecture	No domain graphic available
Description	Catenin alpha-3 (Alpha T-catenin) (Cadherin-associated protein).

KTN1_HUMAN
NC score	0.003124 (rank : 45)	θ value	8.99809 (rank : 42)
Query Neighborhood Hits	43	Target Neighborhood Hits	1197	Shared Neighborhood Hits	10
SwissProt Accessions	Q86UP2, Q13999, Q14707, Q15387, Q86W57	Gene names	KTN1, CG1, KIAA0004
Domain Architecture	No domain graphic available
Description	Kinectin (Kinesin receptor) (CG-1 antigen).