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Network neighborhood for query Sequence : LCTL_HUMAN

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LCTL_HUMAN
SwissProt Accessions	Q6UWM7	Gene names	LCTL, KLPH
Domain Architecture	No domain graphic available
Description	Lactase-like protein precursor (Klotho/lactase-phlorizin hydrolase- related protein).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

LCTL_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	11	Target Neighborhood Hits	11	Shared Neighborhood Hits	11
SwissProt Accessions	Q6UWM7	Gene names	LCTL, KLPH
Domain Architecture	No domain graphic available
Description	Lactase-like protein precursor (Klotho/lactase-phlorizin hydrolase- related protein).

LCTL_MOUSE
θ value	0 (rank : 2)	NC score	0.999238 (rank : 2)
Query Neighborhood Hits	11	Target Neighborhood Hits	11	Shared Neighborhood Hits	8
SwissProt Accessions	Q8K1F9, Q8BPR1, Q8K2M9	Gene names	Lctl, Klph
Domain Architecture	No domain graphic available
Description	Lactase-like protein precursor (Klotho/lactase-phlorizin hydrolase- related protein).

LPH_HUMAN
θ value	1.74296e-136 (rank : 3)	NC score	0.961316 (rank : 4)
Query Neighborhood Hits	11	Target Neighborhood Hits	27	Shared Neighborhood Hits	8
SwissProt Accessions	P09848	Gene names	LCT, LPH
Domain Architecture
Description	Lactase-phlorizin hydrolase precursor (Lactase-glycosylceramidase) [Includes: Lactase (EC 3.2.1.108); Phlorizin hydrolase (EC 3.2.1.62)].

GBA3_HUMAN
θ value	9.30652e-114 (rank : 4)	NC score	0.981178 (rank : 3)
Query Neighborhood Hits	11	Target Neighborhood Hits	12	Shared Neighborhood Hits	8
SwissProt Accessions	Q9H227, Q3MIH4, Q53GG8, Q6NSF4, Q8NHT8, Q9H3T4, Q9H4C6	Gene names	GBA3, CBG, CBGL1
Domain Architecture	No domain graphic available
Description	Cytosolic beta-glucosidase (EC 3.2.1.21) (Cytosolic beta-glucosidase- like protein 1).

KLOTB_MOUSE
θ value	8.17181e-102 (rank : 5)	NC score	0.947671 (rank : 5)
Query Neighborhood Hits	11	Target Neighborhood Hits	11	Shared Neighborhood Hits	8
SwissProt Accessions	Q99N32, Q920J2, Q99N31	Gene names	Klb, Betakl
Domain Architecture	No domain graphic available
Description	Beta klotho (BetaKlotho) (Klotho beta-like protein).

KLOTB_HUMAN
θ value	2.62879e-100 (rank : 6)	NC score	0.946181 (rank : 8)
Query Neighborhood Hits	11	Target Neighborhood Hits	9	Shared Neighborhood Hits	8
SwissProt Accessions	Q86Z14	Gene names	KLB
Domain Architecture	No domain graphic available
Description	Beta klotho (BetaKlotho) (Klotho beta-like protein).

KLOT_HUMAN
θ value	1.44246e-98 (rank : 7)	NC score	0.946432 (rank : 6)
Query Neighborhood Hits	11	Target Neighborhood Hits	14	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UEF7, Q5VZ95, Q96KV5, Q96KW5, Q9UEI9, Q9Y4F0	Gene names	KL
Domain Architecture	No domain graphic available
Description	Klotho precursor (EC 3.2.1.31) [Contains: Klotho peptide].

KLOT_MOUSE
θ value	1.44246e-98 (rank : 8)	NC score	0.946355 (rank : 7)
Query Neighborhood Hits	11	Target Neighborhood Hits	17	Shared Neighborhood Hits	8
SwissProt Accessions	O35082, O70175, O70621	Gene names	Kl
Domain Architecture	No domain graphic available
Description	Klotho precursor (EC 3.2.1.31) [Contains: Klotho peptide].

NC6IP_HUMAN
θ value	3.0926 (rank : 9)	NC score	0.017207 (rank : 9)
Query Neighborhood Hits	11	Target Neighborhood Hits	116	Shared Neighborhood Hits	2
SwissProt Accessions	Q96RS0, Q5GH23, Q8TDG9, Q96QU3, Q9H5V3	Gene names	NCOA6IP, PIMT
Domain Architecture	No domain graphic available
Description	Putative RNA methyltransferase NCOA6IP (EC 2.1.1.-) (Nuclear receptor coactivator 6-interacting protein) (PRIP-interacting protein with methyltransferase motif) (PIPMT) (PIMT) (CLL-associated antigen KW-2) (Hepatocellular carcinoma-associated antigen 137) (HCA137).

TBC10_HUMAN
θ value	5.27518 (rank : 10)	NC score	0.012996 (rank : 10)
Query Neighborhood Hits	11	Target Neighborhood Hits	64	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BXI6, O76053, Q543A2	Gene names	TBC1D10A, EPI64, TBC1D10
Domain Architecture
Description	TBC1 domain family member 10A (EBP50-PDX interactor of 64 kDa) (EPI64 protein).

TBC10_MOUSE
θ value	6.88961 (rank : 11)	NC score	0.012133 (rank : 11)
Query Neighborhood Hits	11	Target Neighborhood Hits	94	Shared Neighborhood Hits	3
SwissProt Accessions	P58802	Gene names	Tbc1d10a, Epi64, Tbc1d10
Domain Architecture
Description	TBC1 domain family member 10A (EBP50-PDX interactor of 64 kDa) (EPI64 protein).

Hits sorted by NC score

LCTL_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	11	Target Neighborhood Hits	11	Shared Neighborhood Hits	11
SwissProt Accessions	Q6UWM7	Gene names	LCTL, KLPH
Domain Architecture	No domain graphic available
Description	Lactase-like protein precursor (Klotho/lactase-phlorizin hydrolase- related protein).

LCTL_MOUSE
NC score	0.999238 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	11	Target Neighborhood Hits	11	Shared Neighborhood Hits	8
SwissProt Accessions	Q8K1F9, Q8BPR1, Q8K2M9	Gene names	Lctl, Klph
Domain Architecture	No domain graphic available
Description	Lactase-like protein precursor (Klotho/lactase-phlorizin hydrolase- related protein).

GBA3_HUMAN
NC score	0.981178 (rank : 3)	θ value	9.30652e-114 (rank : 4)
Query Neighborhood Hits	11	Target Neighborhood Hits	12	Shared Neighborhood Hits	8
SwissProt Accessions	Q9H227, Q3MIH4, Q53GG8, Q6NSF4, Q8NHT8, Q9H3T4, Q9H4C6	Gene names	GBA3, CBG, CBGL1
Domain Architecture	No domain graphic available
Description	Cytosolic beta-glucosidase (EC 3.2.1.21) (Cytosolic beta-glucosidase- like protein 1).

LPH_HUMAN
NC score	0.961316 (rank : 4)	θ value	1.74296e-136 (rank : 3)
Query Neighborhood Hits	11	Target Neighborhood Hits	27	Shared Neighborhood Hits	8
SwissProt Accessions	P09848	Gene names	LCT, LPH
Domain Architecture
Description	Lactase-phlorizin hydrolase precursor (Lactase-glycosylceramidase) [Includes: Lactase (EC 3.2.1.108); Phlorizin hydrolase (EC 3.2.1.62)].

KLOTB_MOUSE
NC score	0.947671 (rank : 5)	θ value	8.17181e-102 (rank : 5)
Query Neighborhood Hits	11	Target Neighborhood Hits	11	Shared Neighborhood Hits	8
SwissProt Accessions	Q99N32, Q920J2, Q99N31	Gene names	Klb, Betakl
Domain Architecture	No domain graphic available
Description	Beta klotho (BetaKlotho) (Klotho beta-like protein).

KLOT_HUMAN
NC score	0.946432 (rank : 6)	θ value	1.44246e-98 (rank : 7)
Query Neighborhood Hits	11	Target Neighborhood Hits	14	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UEF7, Q5VZ95, Q96KV5, Q96KW5, Q9UEI9, Q9Y4F0	Gene names	KL
Domain Architecture	No domain graphic available
Description	Klotho precursor (EC 3.2.1.31) [Contains: Klotho peptide].

KLOT_MOUSE
NC score	0.946355 (rank : 7)	θ value	1.44246e-98 (rank : 8)
Query Neighborhood Hits	11	Target Neighborhood Hits	17	Shared Neighborhood Hits	8
SwissProt Accessions	O35082, O70175, O70621	Gene names	Kl
Domain Architecture	No domain graphic available
Description	Klotho precursor (EC 3.2.1.31) [Contains: Klotho peptide].

KLOTB_HUMAN
NC score	0.946181 (rank : 8)	θ value	2.62879e-100 (rank : 6)
Query Neighborhood Hits	11	Target Neighborhood Hits	9	Shared Neighborhood Hits	8
SwissProt Accessions	Q86Z14	Gene names	KLB
Domain Architecture	No domain graphic available
Description	Beta klotho (BetaKlotho) (Klotho beta-like protein).

NC6IP_HUMAN
NC score	0.017207 (rank : 9)	θ value	3.0926 (rank : 9)
Query Neighborhood Hits	11	Target Neighborhood Hits	116	Shared Neighborhood Hits	2
SwissProt Accessions	Q96RS0, Q5GH23, Q8TDG9, Q96QU3, Q9H5V3	Gene names	NCOA6IP, PIMT
Domain Architecture	No domain graphic available
Description	Putative RNA methyltransferase NCOA6IP (EC 2.1.1.-) (Nuclear receptor coactivator 6-interacting protein) (PRIP-interacting protein with methyltransferase motif) (PIPMT) (PIMT) (CLL-associated antigen KW-2) (Hepatocellular carcinoma-associated antigen 137) (HCA137).

TBC10_HUMAN
NC score	0.012996 (rank : 10)	θ value	5.27518 (rank : 10)
Query Neighborhood Hits	11	Target Neighborhood Hits	64	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BXI6, O76053, Q543A2	Gene names	TBC1D10A, EPI64, TBC1D10
Domain Architecture
Description	TBC1 domain family member 10A (EBP50-PDX interactor of 64 kDa) (EPI64 protein).

TBC10_MOUSE
NC score	0.012133 (rank : 11)	θ value	6.88961 (rank : 11)
Query Neighborhood Hits	11	Target Neighborhood Hits	94	Shared Neighborhood Hits	3
SwissProt Accessions	P58802	Gene names	Tbc1d10a, Epi64, Tbc1d10
Domain Architecture
Description	TBC1 domain family member 10A (EBP50-PDX interactor of 64 kDa) (EPI64 protein).