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Network neighborhood for query Sequence : GBA3_HUMAN

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GBA3_HUMAN
SwissProt Accessions	Q9H227, Q3MIH4, Q53GG8, Q6NSF4, Q8NHT8, Q9H3T4, Q9H4C6	Gene names	GBA3, CBG, CBGL1
Domain Architecture	No domain graphic available
Description	Cytosolic beta-glucosidase (EC 3.2.1.21) (Cytosolic beta-glucosidase- like protein 1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

GBA3_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	12	Target Neighborhood Hits	12	Shared Neighborhood Hits	12
SwissProt Accessions	Q9H227, Q3MIH4, Q53GG8, Q6NSF4, Q8NHT8, Q9H3T4, Q9H4C6	Gene names	GBA3, CBG, CBGL1
Domain Architecture	No domain graphic available
Description	Cytosolic beta-glucosidase (EC 3.2.1.21) (Cytosolic beta-glucosidase- like protein 1).

LPH_HUMAN
θ value	8.67031e-128 (rank : 2)	NC score	0.969467 (rank : 4)
Query Neighborhood Hits	12	Target Neighborhood Hits	27	Shared Neighborhood Hits	8
SwissProt Accessions	P09848	Gene names	LCT, LPH
Domain Architecture
Description	Lactase-phlorizin hydrolase precursor (Lactase-glycosylceramidase) [Includes: Lactase (EC 3.2.1.108); Phlorizin hydrolase (EC 3.2.1.62)].

LCTL_HUMAN
θ value	9.30652e-114 (rank : 3)	NC score	0.981178 (rank : 2)
Query Neighborhood Hits	12	Target Neighborhood Hits	11	Shared Neighborhood Hits	8
SwissProt Accessions	Q6UWM7	Gene names	LCTL, KLPH
Domain Architecture	No domain graphic available
Description	Lactase-like protein precursor (Klotho/lactase-phlorizin hydrolase- related protein).

LCTL_MOUSE
θ value	4.77967e-110 (rank : 4)	NC score	0.980117 (rank : 3)
Query Neighborhood Hits	12	Target Neighborhood Hits	11	Shared Neighborhood Hits	8
SwissProt Accessions	Q8K1F9, Q8BPR1, Q8K2M9	Gene names	Lctl, Klph
Domain Architecture	No domain graphic available
Description	Lactase-like protein precursor (Klotho/lactase-phlorizin hydrolase- related protein).

KLOT_MOUSE
θ value	5.67233e-95 (rank : 5)	NC score	0.957947 (rank : 5)
Query Neighborhood Hits	12	Target Neighborhood Hits	17	Shared Neighborhood Hits	8
SwissProt Accessions	O35082, O70175, O70621	Gene names	Kl
Domain Architecture	No domain graphic available
Description	Klotho precursor (EC 3.2.1.31) [Contains: Klotho peptide].

KLOT_HUMAN
θ value	2.15548e-94 (rank : 6)	NC score	0.957772 (rank : 6)
Query Neighborhood Hits	12	Target Neighborhood Hits	14	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UEF7, Q5VZ95, Q96KV5, Q96KW5, Q9UEI9, Q9Y4F0	Gene names	KL
Domain Architecture	No domain graphic available
Description	Klotho precursor (EC 3.2.1.31) [Contains: Klotho peptide].

KLOTB_MOUSE
θ value	1.35324e-88 (rank : 7)	NC score	0.955469 (rank : 7)
Query Neighborhood Hits	12	Target Neighborhood Hits	11	Shared Neighborhood Hits	8
SwissProt Accessions	Q99N32, Q920J2, Q99N31	Gene names	Klb, Betakl
Domain Architecture	No domain graphic available
Description	Beta klotho (BetaKlotho) (Klotho beta-like protein).

KLOTB_HUMAN
θ value	1.95407e-87 (rank : 8)	NC score	0.954338 (rank : 8)
Query Neighborhood Hits	12	Target Neighborhood Hits	9	Shared Neighborhood Hits	8
SwissProt Accessions	Q86Z14	Gene names	KLB
Domain Architecture	No domain graphic available
Description	Beta klotho (BetaKlotho) (Klotho beta-like protein).

TS1R3_MOUSE
θ value	3.0926 (rank : 9)	NC score	0.008366 (rank : 10)
Query Neighborhood Hits	12	Target Neighborhood Hits	49	Shared Neighborhood Hits	2
SwissProt Accessions	Q925D8, Q91VA4, Q923K0, Q925A4, Q925D9	Gene names	Tas1r3, Sac, T1r3, Tr3
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 3 precursor (Sweet taste receptor T1R3) (Saccharin preference protein).

ST1B1_MOUSE
θ value	4.03905 (rank : 10)	NC score	0.007006 (rank : 11)
Query Neighborhood Hits	12	Target Neighborhood Hits	27	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QWG7, Q8C301, Q9Z2T0	Gene names	Sult1b1
Domain Architecture	No domain graphic available
Description	Sulfotransferase family cytosolic 1B member 1 (EC 2.8.2.-) (Sulfotransferase 1B1) (DOPA/tyrosine sulfotransferase).

EURL_MOUSE
θ value	8.99809 (rank : 11)	NC score	0.011171 (rank : 9)
Query Neighborhood Hits	12	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D7G4	Gene names	Eurl, D16Ertd472e
Domain Architecture
Description	Protein EURL homolog.

UBP47_HUMAN
θ value	8.99809 (rank : 12)	NC score	0.004826 (rank : 12)
Query Neighborhood Hits	12	Target Neighborhood Hits	149	Shared Neighborhood Hits	2
SwissProt Accessions	Q96K76, Q658U0, Q86Y73, Q8TEP6, Q9BWI0, Q9NWN1	Gene names	USP47
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.1.2.15) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47) (Deubiquitinating enzyme 47).

Hits sorted by NC score

GBA3_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	12	Target Neighborhood Hits	12	Shared Neighborhood Hits	12
SwissProt Accessions	Q9H227, Q3MIH4, Q53GG8, Q6NSF4, Q8NHT8, Q9H3T4, Q9H4C6	Gene names	GBA3, CBG, CBGL1
Domain Architecture	No domain graphic available
Description	Cytosolic beta-glucosidase (EC 3.2.1.21) (Cytosolic beta-glucosidase- like protein 1).

LCTL_HUMAN
NC score	0.981178 (rank : 2)	θ value	9.30652e-114 (rank : 3)
Query Neighborhood Hits	12	Target Neighborhood Hits	11	Shared Neighborhood Hits	8
SwissProt Accessions	Q6UWM7	Gene names	LCTL, KLPH
Domain Architecture	No domain graphic available
Description	Lactase-like protein precursor (Klotho/lactase-phlorizin hydrolase- related protein).

LCTL_MOUSE
NC score	0.980117 (rank : 3)	θ value	4.77967e-110 (rank : 4)
Query Neighborhood Hits	12	Target Neighborhood Hits	11	Shared Neighborhood Hits	8
SwissProt Accessions	Q8K1F9, Q8BPR1, Q8K2M9	Gene names	Lctl, Klph
Domain Architecture	No domain graphic available
Description	Lactase-like protein precursor (Klotho/lactase-phlorizin hydrolase- related protein).

LPH_HUMAN
NC score	0.969467 (rank : 4)	θ value	8.67031e-128 (rank : 2)
Query Neighborhood Hits	12	Target Neighborhood Hits	27	Shared Neighborhood Hits	8
SwissProt Accessions	P09848	Gene names	LCT, LPH
Domain Architecture
Description	Lactase-phlorizin hydrolase precursor (Lactase-glycosylceramidase) [Includes: Lactase (EC 3.2.1.108); Phlorizin hydrolase (EC 3.2.1.62)].

KLOT_MOUSE
NC score	0.957947 (rank : 5)	θ value	5.67233e-95 (rank : 5)
Query Neighborhood Hits	12	Target Neighborhood Hits	17	Shared Neighborhood Hits	8
SwissProt Accessions	O35082, O70175, O70621	Gene names	Kl
Domain Architecture	No domain graphic available
Description	Klotho precursor (EC 3.2.1.31) [Contains: Klotho peptide].

KLOT_HUMAN
NC score	0.957772 (rank : 6)	θ value	2.15548e-94 (rank : 6)
Query Neighborhood Hits	12	Target Neighborhood Hits	14	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UEF7, Q5VZ95, Q96KV5, Q96KW5, Q9UEI9, Q9Y4F0	Gene names	KL
Domain Architecture	No domain graphic available
Description	Klotho precursor (EC 3.2.1.31) [Contains: Klotho peptide].

KLOTB_MOUSE
NC score	0.955469 (rank : 7)	θ value	1.35324e-88 (rank : 7)
Query Neighborhood Hits	12	Target Neighborhood Hits	11	Shared Neighborhood Hits	8
SwissProt Accessions	Q99N32, Q920J2, Q99N31	Gene names	Klb, Betakl
Domain Architecture	No domain graphic available
Description	Beta klotho (BetaKlotho) (Klotho beta-like protein).

KLOTB_HUMAN
NC score	0.954338 (rank : 8)	θ value	1.95407e-87 (rank : 8)
Query Neighborhood Hits	12	Target Neighborhood Hits	9	Shared Neighborhood Hits	8
SwissProt Accessions	Q86Z14	Gene names	KLB
Domain Architecture	No domain graphic available
Description	Beta klotho (BetaKlotho) (Klotho beta-like protein).

EURL_MOUSE
NC score	0.011171 (rank : 9)	θ value	8.99809 (rank : 11)
Query Neighborhood Hits	12	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D7G4	Gene names	Eurl, D16Ertd472e
Domain Architecture
Description	Protein EURL homolog.

TS1R3_MOUSE
NC score	0.008366 (rank : 10)	θ value	3.0926 (rank : 9)
Query Neighborhood Hits	12	Target Neighborhood Hits	49	Shared Neighborhood Hits	2
SwissProt Accessions	Q925D8, Q91VA4, Q923K0, Q925A4, Q925D9	Gene names	Tas1r3, Sac, T1r3, Tr3
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 3 precursor (Sweet taste receptor T1R3) (Saccharin preference protein).

ST1B1_MOUSE
NC score	0.007006 (rank : 11)	θ value	4.03905 (rank : 10)
Query Neighborhood Hits	12	Target Neighborhood Hits	27	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QWG7, Q8C301, Q9Z2T0	Gene names	Sult1b1
Domain Architecture	No domain graphic available
Description	Sulfotransferase family cytosolic 1B member 1 (EC 2.8.2.-) (Sulfotransferase 1B1) (DOPA/tyrosine sulfotransferase).

UBP47_HUMAN
NC score	0.004826 (rank : 12)	θ value	8.99809 (rank : 12)
Query Neighborhood Hits	12	Target Neighborhood Hits	149	Shared Neighborhood Hits	2
SwissProt Accessions	Q96K76, Q658U0, Q86Y73, Q8TEP6, Q9BWI0, Q9NWN1	Gene names	USP47
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.1.2.15) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47) (Deubiquitinating enzyme 47).