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Network neighborhood for query Sequence : G6PE_HUMAN

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G6PE_HUMAN
SwissProt Accessions	O95479, Q4TT33, Q66I35, Q68DT3	Gene names	H6PD, GDH
Domain Architecture
Description	GDH/6PGL endoplasmic bifunctional protein precursor [Includes: Glucose 1-dehydrogenase (EC 1.1.1.47) (Hexose-6-phosphate dehydrogenase); 6- phosphogluconolactonase (EC 3.1.1.31) (6PGL)].
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

G6PE_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	18	Target Neighborhood Hits	18	Shared Neighborhood Hits	18
SwissProt Accessions	O95479, Q4TT33, Q66I35, Q68DT3	Gene names	H6PD, GDH
Domain Architecture
Description	GDH/6PGL endoplasmic bifunctional protein precursor [Includes: Glucose 1-dehydrogenase (EC 1.1.1.47) (Hexose-6-phosphate dehydrogenase); 6- phosphogluconolactonase (EC 3.1.1.31) (6PGL)].

G6PE_MOUSE
θ value	0 (rank : 2)	NC score	0.996489 (rank : 2)
Query Neighborhood Hits	18	Target Neighborhood Hits	12	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CFX1, Q8BLH1	Gene names	H6pd
Domain Architecture	No domain graphic available
Description	GDH/6PGL endoplasmic bifunctional protein precursor [Includes: Glucose 1-dehydrogenase (EC 1.1.1.47) (Hexose-6-phosphate dehydrogenase); 6- phosphogluconolactonase (EC 3.1.1.31) (6PGL)].

G6PD1_MOUSE
θ value	1.90589e-58 (rank : 3)	NC score	0.813292 (rank : 4)
Query Neighborhood Hits	18	Target Neighborhood Hits	11	Shared Neighborhood Hits	5
SwissProt Accessions	Q00612	Gene names	G6pdx, G6pd, G6pd-1
Domain Architecture
Description	Glucose-6-phosphate 1-dehydrogenase X (EC 1.1.1.49) (G6PD).

G6PD_HUMAN
θ value	2.48917e-58 (rank : 4)	NC score	0.814287 (rank : 3)
Query Neighborhood Hits	18	Target Neighborhood Hits	9	Shared Neighborhood Hits	5
SwissProt Accessions	P11413, Q16000, Q16765, Q8IU70, Q8IU88, Q8IUA6, Q96PQ2	Gene names	G6PD
Domain Architecture
Description	Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) (G6PD).

G6PD2_MOUSE
θ value	2.041e-52 (rank : 5)	NC score	0.806428 (rank : 5)
Query Neighborhood Hits	18	Target Neighborhood Hits	9	Shared Neighborhood Hits	5
SwissProt Accessions	P97324	Gene names	G6pd2, G6pd-2
Domain Architecture
Description	Glucose-6-phosphate 1-dehydrogenase 2 (EC 1.1.1.49) (G6PD).

6PGL_HUMAN
θ value	1.2077e-20 (rank : 6)	NC score	0.567096 (rank : 6)
Query Neighborhood Hits	18	Target Neighborhood Hits	7	Shared Neighborhood Hits	4
SwissProt Accessions	O95336	Gene names	PGLS
Domain Architecture
Description	6-phosphogluconolactonase (EC 3.1.1.31) (6PGL).

6PGL_MOUSE
θ value	6.62687e-19 (rank : 7)	NC score	0.552774 (rank : 7)
Query Neighborhood Hits	18	Target Neighborhood Hits	10	Shared Neighborhood Hits	4
SwissProt Accessions	Q9CQ60, Q3TA62	Gene names	Pgls
Domain Architecture	No domain graphic available
Description	6-phosphogluconolactonase (EC 3.1.1.31) (6PGL).

ZCHC6_MOUSE
θ value	0.0961366 (rank : 8)	NC score	0.063572 (rank : 8)
Query Neighborhood Hits	18	Target Neighborhood Hits	90	Shared Neighborhood Hits	4
SwissProt Accessions	Q5BLK4, Q8CIH3	Gene names	Zcchc6
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 6.

ZCHC6_HUMAN
θ value	0.47712 (rank : 9)	NC score	0.057425 (rank : 9)
Query Neighborhood Hits	18	Target Neighborhood Hits	142	Shared Neighborhood Hits	4
SwissProt Accessions	Q5VYS8, Q5H9T0, Q5VYS5, Q5VYS7, Q658Z9, Q659A2, Q6MZJ3, Q8N5F0, Q96N57, Q96NE8, Q9C0F2, Q9H8M6	Gene names	ZCCHC6, KIAA1711
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 6.

PKD2_HUMAN
θ value	0.813845 (rank : 10)	NC score	0.022179 (rank : 13)
Query Neighborhood Hits	18	Target Neighborhood Hits	105	Shared Neighborhood Hits	4
SwissProt Accessions	Q13563, O60441, Q15764	Gene names	PKD2
Domain Architecture
Description	Polycystin-2 (Polycystic kidney disease 2 protein homolog) (Autosomal dominant polycystic kidney disease type II protein) (Polycystwin) (R48321).

RNF25_HUMAN
θ value	2.36792 (rank : 11)	NC score	0.024188 (rank : 11)
Query Neighborhood Hits	18	Target Neighborhood Hits	163	Shared Neighborhood Hits	2
SwissProt Accessions	Q96BH1, Q9H874	Gene names	RNF25
Domain Architecture
Description	RING finger protein 25 (EC 6.3.2.-).

ITPR1_HUMAN
θ value	3.0926 (rank : 12)	NC score	0.017977 (rank : 16)
Query Neighborhood Hits	18	Target Neighborhood Hits	90	Shared Neighborhood Hits	4
SwissProt Accessions	Q14643, Q14660, Q99897	Gene names	ITPR1, INSP3R1
Domain Architecture
Description	Inositol 1,4,5-trisphosphate receptor type 1 (Type 1 inositol 1,4,5- trisphosphate receptor) (Type 1 InsP3 receptor) (IP3 receptor isoform 1) (InsP3R1) (IP3R).

ITPR1_MOUSE
θ value	3.0926 (rank : 13)	NC score	0.017980 (rank : 15)
Query Neighborhood Hits	18	Target Neighborhood Hits	99	Shared Neighborhood Hits	4
SwissProt Accessions	P11881, P20943, Q99LG5	Gene names	Itpr1, Insp3r, Pcd6, Pcp1
Domain Architecture
Description	Inositol 1,4,5-trisphosphate receptor type 1 (Type 1 inositol 1,4,5- trisphosphate receptor) (Type 1 InsP3 receptor) (IP3 receptor isoform 1) (InsP3R1) (Inositol 1,4,5-trisphosphate-binding protein P400) (Purkinje cell protein 1) (Protein PCD-6).

PCNT_HUMAN
θ value	3.0926 (rank : 14)	NC score	0.005507 (rank : 17)
Query Neighborhood Hits	18	Target Neighborhood Hits	1551	Shared Neighborhood Hits	2
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

TTC7A_HUMAN
θ value	3.0926 (rank : 15)	NC score	0.024088 (rank : 12)
Query Neighborhood Hits	18	Target Neighborhood Hits	79	Shared Neighborhood Hits	3
SwissProt Accessions	Q9ULT0, Q6PIX4, Q8ND67, Q9BUS3	Gene names	TTC7A, KIAA1140, TTC7
Domain Architecture
Description	Tetratricopeptide repeat protein 7A (TPR repeat protein 7).

ZN513_HUMAN
θ value	3.0926 (rank : 16)	NC score	0.000802 (rank : 18)
Query Neighborhood Hits	18	Target Neighborhood Hits	709	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N8E2	Gene names	ZNF513
Domain Architecture	No domain graphic available
Description	Zinc finger protein 513.

ZCH11_HUMAN
θ value	5.27518 (rank : 17)	NC score	0.041301 (rank : 10)
Query Neighborhood Hits	18	Target Neighborhood Hits	278	Shared Neighborhood Hits	4
SwissProt Accessions	Q5TAX3, Q12764, Q5TAX4, Q86XZ3	Gene names	ZCCHC11, KIAA0191
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 11.

TTC7A_MOUSE
θ value	6.88961 (rank : 18)	NC score	0.020470 (rank : 14)
Query Neighborhood Hits	18	Target Neighborhood Hits	85	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BGB2, Q80XT5	Gene names	Ttc7a, Ttc7
Domain Architecture
Description	Tetratricopeptide repeat protein 7A (TPR repeat protein 7).

Hits sorted by NC score

G6PE_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	18	Target Neighborhood Hits	18	Shared Neighborhood Hits	18
SwissProt Accessions	O95479, Q4TT33, Q66I35, Q68DT3	Gene names	H6PD, GDH
Domain Architecture
Description	GDH/6PGL endoplasmic bifunctional protein precursor [Includes: Glucose 1-dehydrogenase (EC 1.1.1.47) (Hexose-6-phosphate dehydrogenase); 6- phosphogluconolactonase (EC 3.1.1.31) (6PGL)].

G6PE_MOUSE
NC score	0.996489 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	18	Target Neighborhood Hits	12	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CFX1, Q8BLH1	Gene names	H6pd
Domain Architecture	No domain graphic available
Description	GDH/6PGL endoplasmic bifunctional protein precursor [Includes: Glucose 1-dehydrogenase (EC 1.1.1.47) (Hexose-6-phosphate dehydrogenase); 6- phosphogluconolactonase (EC 3.1.1.31) (6PGL)].

G6PD_HUMAN
NC score	0.814287 (rank : 3)	θ value	2.48917e-58 (rank : 4)
Query Neighborhood Hits	18	Target Neighborhood Hits	9	Shared Neighborhood Hits	5
SwissProt Accessions	P11413, Q16000, Q16765, Q8IU70, Q8IU88, Q8IUA6, Q96PQ2	Gene names	G6PD
Domain Architecture
Description	Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) (G6PD).

G6PD1_MOUSE
NC score	0.813292 (rank : 4)	θ value	1.90589e-58 (rank : 3)
Query Neighborhood Hits	18	Target Neighborhood Hits	11	Shared Neighborhood Hits	5
SwissProt Accessions	Q00612	Gene names	G6pdx, G6pd, G6pd-1
Domain Architecture
Description	Glucose-6-phosphate 1-dehydrogenase X (EC 1.1.1.49) (G6PD).

G6PD2_MOUSE
NC score	0.806428 (rank : 5)	θ value	2.041e-52 (rank : 5)
Query Neighborhood Hits	18	Target Neighborhood Hits	9	Shared Neighborhood Hits	5
SwissProt Accessions	P97324	Gene names	G6pd2, G6pd-2
Domain Architecture
Description	Glucose-6-phosphate 1-dehydrogenase 2 (EC 1.1.1.49) (G6PD).

6PGL_HUMAN
NC score	0.567096 (rank : 6)	θ value	1.2077e-20 (rank : 6)
Query Neighborhood Hits	18	Target Neighborhood Hits	7	Shared Neighborhood Hits	4
SwissProt Accessions	O95336	Gene names	PGLS
Domain Architecture
Description	6-phosphogluconolactonase (EC 3.1.1.31) (6PGL).

6PGL_MOUSE
NC score	0.552774 (rank : 7)	θ value	6.62687e-19 (rank : 7)
Query Neighborhood Hits	18	Target Neighborhood Hits	10	Shared Neighborhood Hits	4
SwissProt Accessions	Q9CQ60, Q3TA62	Gene names	Pgls
Domain Architecture	No domain graphic available
Description	6-phosphogluconolactonase (EC 3.1.1.31) (6PGL).

ZCHC6_MOUSE
NC score	0.063572 (rank : 8)	θ value	0.0961366 (rank : 8)
Query Neighborhood Hits	18	Target Neighborhood Hits	90	Shared Neighborhood Hits	4
SwissProt Accessions	Q5BLK4, Q8CIH3	Gene names	Zcchc6
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 6.

ZCHC6_HUMAN
NC score	0.057425 (rank : 9)	θ value	0.47712 (rank : 9)
Query Neighborhood Hits	18	Target Neighborhood Hits	142	Shared Neighborhood Hits	4
SwissProt Accessions	Q5VYS8, Q5H9T0, Q5VYS5, Q5VYS7, Q658Z9, Q659A2, Q6MZJ3, Q8N5F0, Q96N57, Q96NE8, Q9C0F2, Q9H8M6	Gene names	ZCCHC6, KIAA1711
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 6.

ZCH11_HUMAN
NC score	0.041301 (rank : 10)	θ value	5.27518 (rank : 17)
Query Neighborhood Hits	18	Target Neighborhood Hits	278	Shared Neighborhood Hits	4
SwissProt Accessions	Q5TAX3, Q12764, Q5TAX4, Q86XZ3	Gene names	ZCCHC11, KIAA0191
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 11.

RNF25_HUMAN
NC score	0.024188 (rank : 11)	θ value	2.36792 (rank : 11)
Query Neighborhood Hits	18	Target Neighborhood Hits	163	Shared Neighborhood Hits	2
SwissProt Accessions	Q96BH1, Q9H874	Gene names	RNF25
Domain Architecture
Description	RING finger protein 25 (EC 6.3.2.-).

TTC7A_HUMAN
NC score	0.024088 (rank : 12)	θ value	3.0926 (rank : 15)
Query Neighborhood Hits	18	Target Neighborhood Hits	79	Shared Neighborhood Hits	3
SwissProt Accessions	Q9ULT0, Q6PIX4, Q8ND67, Q9BUS3	Gene names	TTC7A, KIAA1140, TTC7
Domain Architecture
Description	Tetratricopeptide repeat protein 7A (TPR repeat protein 7).

PKD2_HUMAN
NC score	0.022179 (rank : 13)	θ value	0.813845 (rank : 10)
Query Neighborhood Hits	18	Target Neighborhood Hits	105	Shared Neighborhood Hits	4
SwissProt Accessions	Q13563, O60441, Q15764	Gene names	PKD2
Domain Architecture
Description	Polycystin-2 (Polycystic kidney disease 2 protein homolog) (Autosomal dominant polycystic kidney disease type II protein) (Polycystwin) (R48321).

TTC7A_MOUSE
NC score	0.020470 (rank : 14)	θ value	6.88961 (rank : 18)
Query Neighborhood Hits	18	Target Neighborhood Hits	85	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BGB2, Q80XT5	Gene names	Ttc7a, Ttc7
Domain Architecture
Description	Tetratricopeptide repeat protein 7A (TPR repeat protein 7).

ITPR1_MOUSE
NC score	0.017980 (rank : 15)	θ value	3.0926 (rank : 13)
Query Neighborhood Hits	18	Target Neighborhood Hits	99	Shared Neighborhood Hits	4
SwissProt Accessions	P11881, P20943, Q99LG5	Gene names	Itpr1, Insp3r, Pcd6, Pcp1
Domain Architecture
Description	Inositol 1,4,5-trisphosphate receptor type 1 (Type 1 inositol 1,4,5- trisphosphate receptor) (Type 1 InsP3 receptor) (IP3 receptor isoform 1) (InsP3R1) (Inositol 1,4,5-trisphosphate-binding protein P400) (Purkinje cell protein 1) (Protein PCD-6).

ITPR1_HUMAN
NC score	0.017977 (rank : 16)	θ value	3.0926 (rank : 12)
Query Neighborhood Hits	18	Target Neighborhood Hits	90	Shared Neighborhood Hits	4
SwissProt Accessions	Q14643, Q14660, Q99897	Gene names	ITPR1, INSP3R1
Domain Architecture
Description	Inositol 1,4,5-trisphosphate receptor type 1 (Type 1 inositol 1,4,5- trisphosphate receptor) (Type 1 InsP3 receptor) (IP3 receptor isoform 1) (InsP3R1) (IP3R).

PCNT_HUMAN
NC score	0.005507 (rank : 17)	θ value	3.0926 (rank : 14)
Query Neighborhood Hits	18	Target Neighborhood Hits	1551	Shared Neighborhood Hits	2
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

ZN513_HUMAN
NC score	0.000802 (rank : 18)	θ value	3.0926 (rank : 16)
Query Neighborhood Hits	18	Target Neighborhood Hits	709	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N8E2	Gene names	ZNF513
Domain Architecture	No domain graphic available
Description	Zinc finger protein 513.