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Network neighborhood for query Sequence : EXOS8_MOUSE

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EXOS8_MOUSE
SwissProt Accessions	Q9D753	Gene names	Exosc8, Rrp43
Domain Architecture	No domain graphic available
Description	Exosome complex exonuclease RRP43 (EC 3.1.13.-) (Ribosomal RNA- processing protein 43) (Exosome component 8).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

EXOS8_MOUSE
θ value	1.62005e-158 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	10	Target Neighborhood Hits	10	Shared Neighborhood Hits	10
SwissProt Accessions	Q9D753	Gene names	Exosc8, Rrp43
Domain Architecture	No domain graphic available
Description	Exosome complex exonuclease RRP43 (EC 3.1.13.-) (Ribosomal RNA- processing protein 43) (Exosome component 8).

EXOS8_HUMAN
θ value	1.1637e-148 (rank : 2)	NC score	0.999543 (rank : 2)
Query Neighborhood Hits	10	Target Neighborhood Hits	10	Shared Neighborhood Hits	10
SwissProt Accessions	Q96B26, O43480	Gene names	EXOSC8, OIP2, RRP43
Domain Architecture
Description	Exosome complex exonuclease RRP43 (EC 3.1.13.-) (Ribosomal RNA- processing protein 43) (Exosome component 8) (p9) (Opa-interacting protein 2).

EXOS7_HUMAN
θ value	6.61148e-27 (rank : 3)	NC score	0.808231 (rank : 3)
Query Neighborhood Hits	10	Target Neighborhood Hits	7	Shared Neighborhood Hits	6
SwissProt Accessions	Q15024, Q96E72	Gene names	EXOSC7, KIAA0116, RRP42
Domain Architecture
Description	Exosome complex exonuclease RRP42 (EC 3.1.13.-) (Ribosomal RNA- processing protein 42) (Exosome component 7) (p8).

EXOS9_MOUSE
θ value	2.51237e-26 (rank : 4)	NC score	0.794074 (rank : 5)
Query Neighborhood Hits	10	Target Neighborhood Hits	11	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JHI7, Q9CSZ2	Gene names	Exosc9, Pmscl1
Domain Architecture
Description	Exosome complex exonuclease RRP45 (EC 3.1.13.-) (Exosome component 9) (Polymyositis/scleroderma autoantigen 1) (Autoantigen PM/Scl 1) (Polymyositis/scleroderma autoantigen 75 kDa) (PM/Scl-75) (P75 polymyositis-scleroderma overlap syndrome-associated autoantigen).

EXOS7_MOUSE
θ value	5.59698e-26 (rank : 5)	NC score	0.800695 (rank : 4)
Query Neighborhood Hits	10	Target Neighborhood Hits	7	Shared Neighborhood Hits	6
SwissProt Accessions	Q9D0M0, Q9CT77	Gene names	Exosc7, Rrp42
Domain Architecture
Description	Exosome complex exonuclease RRP42 (EC 3.1.13.-) (Ribosomal RNA- processing protein 42) (Exosome component 7).

EXOS9_HUMAN
θ value	1.37858e-24 (rank : 6)	NC score	0.782307 (rank : 6)
Query Neighborhood Hits	10	Target Neighborhood Hits	10	Shared Neighborhood Hits	6
SwissProt Accessions	Q06265, Q12883	Gene names	EXOSC9, PMSCL1
Domain Architecture
Description	Exosome complex exonuclease RRP45 (EC 3.1.13.-) (Exosome component 9) (Polymyositis/scleroderma autoantigen 1) (Autoantigen PM/Scl 1) (Polymyositis/scleroderma autoantigen 75 kDa) (PM/Scl-75) (P75 polymyositis-scleroderma overlap syndrome-associated autoantigen).

EXOS4_HUMAN
θ value	0.125558 (rank : 7)	NC score	0.136095 (rank : 8)
Query Neighborhood Hits	10	Target Neighborhood Hits	8	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NPD3	Gene names	EXOSC4, RRP41, SKI6
Domain Architecture
Description	Exosome complex exonuclease RRP41 (EC 3.1.13.-) (Ribosomal RNA- processing protein 41) (Exosome component 4) (p12A).

EXOS4_MOUSE
θ value	0.163984 (rank : 8)	NC score	0.137024 (rank : 7)
Query Neighborhood Hits	10	Target Neighborhood Hits	8	Shared Neighborhood Hits	6
SwissProt Accessions	Q921I9	Gene names	Exosc4, Rrp41
Domain Architecture
Description	Exosome complex exonuclease RRP41 (EC 3.1.13.-) (Ribosomal RNA- processing protein 41) (Exosome component 4).

PNPT1_HUMAN
θ value	0.365318 (rank : 9)	NC score	0.104596 (rank : 9)
Query Neighborhood Hits	10	Target Neighborhood Hits	30	Shared Neighborhood Hits	6
SwissProt Accessions	Q8TCS8, Q53SU0, Q68CN1, Q7Z7D1, Q8IWX1, Q96T05, Q9BRU3, Q9BVX0	Gene names	PNPT1, PNPASE
Domain Architecture	No domain graphic available
Description	Polyribonucleotide nucleotidyltransferase 1, mitochondrial precursor (EC 2.7.7.8) (PNPase 1) (Polynucleotide phosphorylase-like protein) (PNPase old-35) (3'-5' RNA exonuclease OLD35).

PNPT1_MOUSE
θ value	0.47712 (rank : 10)	NC score	0.102920 (rank : 10)
Query Neighborhood Hits	10	Target Neighborhood Hits	21	Shared Neighborhood Hits	6
SwissProt Accessions	Q8K1R3, Q3UEP9, Q810U7, Q812B3, Q8R2U3, Q9DC52	Gene names	Pnpt1, Pnpase
Domain Architecture	No domain graphic available
Description	Polyribonucleotide nucleotidyltransferase 1, mitochondrial precursor (EC 2.7.7.8) (PNPase 1) (Polynucleotide phosphorylase-like protein) (PNPase old-35) (3'-5' RNA exonuclease OLD35).

Hits sorted by NC score

EXOS8_MOUSE
NC score	0.999962 (rank : 1)	θ value	1.62005e-158 (rank : 1)
Query Neighborhood Hits	10	Target Neighborhood Hits	10	Shared Neighborhood Hits	10
SwissProt Accessions	Q9D753	Gene names	Exosc8, Rrp43
Domain Architecture	No domain graphic available
Description	Exosome complex exonuclease RRP43 (EC 3.1.13.-) (Ribosomal RNA- processing protein 43) (Exosome component 8).

EXOS8_HUMAN
NC score	0.999543 (rank : 2)	θ value	1.1637e-148 (rank : 2)
Query Neighborhood Hits	10	Target Neighborhood Hits	10	Shared Neighborhood Hits	10
SwissProt Accessions	Q96B26, O43480	Gene names	EXOSC8, OIP2, RRP43
Domain Architecture
Description	Exosome complex exonuclease RRP43 (EC 3.1.13.-) (Ribosomal RNA- processing protein 43) (Exosome component 8) (p9) (Opa-interacting protein 2).

EXOS7_HUMAN
NC score	0.808231 (rank : 3)	θ value	6.61148e-27 (rank : 3)
Query Neighborhood Hits	10	Target Neighborhood Hits	7	Shared Neighborhood Hits	6
SwissProt Accessions	Q15024, Q96E72	Gene names	EXOSC7, KIAA0116, RRP42
Domain Architecture
Description	Exosome complex exonuclease RRP42 (EC 3.1.13.-) (Ribosomal RNA- processing protein 42) (Exosome component 7) (p8).

EXOS7_MOUSE
NC score	0.800695 (rank : 4)	θ value	5.59698e-26 (rank : 5)
Query Neighborhood Hits	10	Target Neighborhood Hits	7	Shared Neighborhood Hits	6
SwissProt Accessions	Q9D0M0, Q9CT77	Gene names	Exosc7, Rrp42
Domain Architecture
Description	Exosome complex exonuclease RRP42 (EC 3.1.13.-) (Ribosomal RNA- processing protein 42) (Exosome component 7).

EXOS9_MOUSE
NC score	0.794074 (rank : 5)	θ value	2.51237e-26 (rank : 4)
Query Neighborhood Hits	10	Target Neighborhood Hits	11	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JHI7, Q9CSZ2	Gene names	Exosc9, Pmscl1
Domain Architecture
Description	Exosome complex exonuclease RRP45 (EC 3.1.13.-) (Exosome component 9) (Polymyositis/scleroderma autoantigen 1) (Autoantigen PM/Scl 1) (Polymyositis/scleroderma autoantigen 75 kDa) (PM/Scl-75) (P75 polymyositis-scleroderma overlap syndrome-associated autoantigen).

EXOS9_HUMAN
NC score	0.782307 (rank : 6)	θ value	1.37858e-24 (rank : 6)
Query Neighborhood Hits	10	Target Neighborhood Hits	10	Shared Neighborhood Hits	6
SwissProt Accessions	Q06265, Q12883	Gene names	EXOSC9, PMSCL1
Domain Architecture
Description	Exosome complex exonuclease RRP45 (EC 3.1.13.-) (Exosome component 9) (Polymyositis/scleroderma autoantigen 1) (Autoantigen PM/Scl 1) (Polymyositis/scleroderma autoantigen 75 kDa) (PM/Scl-75) (P75 polymyositis-scleroderma overlap syndrome-associated autoantigen).

EXOS4_MOUSE
NC score	0.137024 (rank : 7)	θ value	0.163984 (rank : 8)
Query Neighborhood Hits	10	Target Neighborhood Hits	8	Shared Neighborhood Hits	6
SwissProt Accessions	Q921I9	Gene names	Exosc4, Rrp41
Domain Architecture
Description	Exosome complex exonuclease RRP41 (EC 3.1.13.-) (Ribosomal RNA- processing protein 41) (Exosome component 4).

EXOS4_HUMAN
NC score	0.136095 (rank : 8)	θ value	0.125558 (rank : 7)
Query Neighborhood Hits	10	Target Neighborhood Hits	8	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NPD3	Gene names	EXOSC4, RRP41, SKI6
Domain Architecture
Description	Exosome complex exonuclease RRP41 (EC 3.1.13.-) (Ribosomal RNA- processing protein 41) (Exosome component 4) (p12A).

PNPT1_HUMAN
NC score	0.104596 (rank : 9)	θ value	0.365318 (rank : 9)
Query Neighborhood Hits	10	Target Neighborhood Hits	30	Shared Neighborhood Hits	6
SwissProt Accessions	Q8TCS8, Q53SU0, Q68CN1, Q7Z7D1, Q8IWX1, Q96T05, Q9BRU3, Q9BVX0	Gene names	PNPT1, PNPASE
Domain Architecture	No domain graphic available
Description	Polyribonucleotide nucleotidyltransferase 1, mitochondrial precursor (EC 2.7.7.8) (PNPase 1) (Polynucleotide phosphorylase-like protein) (PNPase old-35) (3'-5' RNA exonuclease OLD35).

PNPT1_MOUSE
NC score	0.102920 (rank : 10)	θ value	0.47712 (rank : 10)
Query Neighborhood Hits	10	Target Neighborhood Hits	21	Shared Neighborhood Hits	6
SwissProt Accessions	Q8K1R3, Q3UEP9, Q810U7, Q812B3, Q8R2U3, Q9DC52	Gene names	Pnpt1, Pnpase
Domain Architecture	No domain graphic available
Description	Polyribonucleotide nucleotidyltransferase 1, mitochondrial precursor (EC 2.7.7.8) (PNPase 1) (Polynucleotide phosphorylase-like protein) (PNPase old-35) (3'-5' RNA exonuclease OLD35).