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Network neighborhood for query Sequence : EXOS7_HUMAN

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EXOS7_HUMAN
SwissProt Accessions	Q15024, Q96E72	Gene names	EXOSC7, KIAA0116, RRP42
Domain Architecture
Description	Exosome complex exonuclease RRP42 (EC 3.1.13.-) (Ribosomal RNA- processing protein 42) (Exosome component 7) (p8).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

EXOS7_HUMAN
θ value	6.14192e-166 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	7	Target Neighborhood Hits	7	Shared Neighborhood Hits	7
SwissProt Accessions	Q15024, Q96E72	Gene names	EXOSC7, KIAA0116, RRP42
Domain Architecture
Description	Exosome complex exonuclease RRP42 (EC 3.1.13.-) (Ribosomal RNA- processing protein 42) (Exosome component 7) (p8).

EXOS7_MOUSE
θ value	7.04359e-154 (rank : 2)	NC score	0.998999 (rank : 2)
Query Neighborhood Hits	7	Target Neighborhood Hits	7	Shared Neighborhood Hits	6
SwissProt Accessions	Q9D0M0, Q9CT77	Gene names	Exosc7, Rrp42
Domain Architecture
Description	Exosome complex exonuclease RRP42 (EC 3.1.13.-) (Ribosomal RNA- processing protein 42) (Exosome component 7).

EXOS8_MOUSE
θ value	6.61148e-27 (rank : 3)	NC score	0.808231 (rank : 3)
Query Neighborhood Hits	7	Target Neighborhood Hits	10	Shared Neighborhood Hits	6
SwissProt Accessions	Q9D753	Gene names	Exosc8, Rrp43
Domain Architecture	No domain graphic available
Description	Exosome complex exonuclease RRP43 (EC 3.1.13.-) (Ribosomal RNA- processing protein 43) (Exosome component 8).

EXOS8_HUMAN
θ value	1.05554e-24 (rank : 4)	NC score	0.798868 (rank : 4)
Query Neighborhood Hits	7	Target Neighborhood Hits	10	Shared Neighborhood Hits	6
SwissProt Accessions	Q96B26, O43480	Gene names	EXOSC8, OIP2, RRP43
Domain Architecture
Description	Exosome complex exonuclease RRP43 (EC 3.1.13.-) (Ribosomal RNA- processing protein 43) (Exosome component 8) (p9) (Opa-interacting protein 2).

EXOS9_MOUSE
θ value	8.93572e-24 (rank : 5)	NC score	0.756749 (rank : 5)
Query Neighborhood Hits	7	Target Neighborhood Hits	11	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JHI7, Q9CSZ2	Gene names	Exosc9, Pmscl1
Domain Architecture
Description	Exosome complex exonuclease RRP45 (EC 3.1.13.-) (Exosome component 9) (Polymyositis/scleroderma autoantigen 1) (Autoantigen PM/Scl 1) (Polymyositis/scleroderma autoantigen 75 kDa) (PM/Scl-75) (P75 polymyositis-scleroderma overlap syndrome-associated autoantigen).

EXOS9_HUMAN
θ value	2.27762e-19 (rank : 6)	NC score	0.732618 (rank : 6)
Query Neighborhood Hits	7	Target Neighborhood Hits	10	Shared Neighborhood Hits	6
SwissProt Accessions	Q06265, Q12883	Gene names	EXOSC9, PMSCL1
Domain Architecture
Description	Exosome complex exonuclease RRP45 (EC 3.1.13.-) (Exosome component 9) (Polymyositis/scleroderma autoantigen 1) (Autoantigen PM/Scl 1) (Polymyositis/scleroderma autoantigen 75 kDa) (PM/Scl-75) (P75 polymyositis-scleroderma overlap syndrome-associated autoantigen).

P3C2A_MOUSE
θ value	5.27518 (rank : 7)	NC score	0.008697 (rank : 7)
Query Neighborhood Hits	7	Target Neighborhood Hits	181	Shared Neighborhood Hits	2
SwissProt Accessions	Q61194, Q61182	Gene names	Pik3c2a, Cpk
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-alpha) (PtdIns-3-kinase C2 alpha) (PI3K-C2alpha) (Cpk-m) (p170).

Hits sorted by NC score

EXOS7_HUMAN
NC score	0.999962 (rank : 1)	θ value	6.14192e-166 (rank : 1)
Query Neighborhood Hits	7	Target Neighborhood Hits	7	Shared Neighborhood Hits	7
SwissProt Accessions	Q15024, Q96E72	Gene names	EXOSC7, KIAA0116, RRP42
Domain Architecture
Description	Exosome complex exonuclease RRP42 (EC 3.1.13.-) (Ribosomal RNA- processing protein 42) (Exosome component 7) (p8).

EXOS7_MOUSE
NC score	0.998999 (rank : 2)	θ value	7.04359e-154 (rank : 2)
Query Neighborhood Hits	7	Target Neighborhood Hits	7	Shared Neighborhood Hits	6
SwissProt Accessions	Q9D0M0, Q9CT77	Gene names	Exosc7, Rrp42
Domain Architecture
Description	Exosome complex exonuclease RRP42 (EC 3.1.13.-) (Ribosomal RNA- processing protein 42) (Exosome component 7).

EXOS8_MOUSE
NC score	0.808231 (rank : 3)	θ value	6.61148e-27 (rank : 3)
Query Neighborhood Hits	7	Target Neighborhood Hits	10	Shared Neighborhood Hits	6
SwissProt Accessions	Q9D753	Gene names	Exosc8, Rrp43
Domain Architecture	No domain graphic available
Description	Exosome complex exonuclease RRP43 (EC 3.1.13.-) (Ribosomal RNA- processing protein 43) (Exosome component 8).

EXOS8_HUMAN
NC score	0.798868 (rank : 4)	θ value	1.05554e-24 (rank : 4)
Query Neighborhood Hits	7	Target Neighborhood Hits	10	Shared Neighborhood Hits	6
SwissProt Accessions	Q96B26, O43480	Gene names	EXOSC8, OIP2, RRP43
Domain Architecture
Description	Exosome complex exonuclease RRP43 (EC 3.1.13.-) (Ribosomal RNA- processing protein 43) (Exosome component 8) (p9) (Opa-interacting protein 2).

EXOS9_MOUSE
NC score	0.756749 (rank : 5)	θ value	8.93572e-24 (rank : 5)
Query Neighborhood Hits	7	Target Neighborhood Hits	11	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JHI7, Q9CSZ2	Gene names	Exosc9, Pmscl1
Domain Architecture
Description	Exosome complex exonuclease RRP45 (EC 3.1.13.-) (Exosome component 9) (Polymyositis/scleroderma autoantigen 1) (Autoantigen PM/Scl 1) (Polymyositis/scleroderma autoantigen 75 kDa) (PM/Scl-75) (P75 polymyositis-scleroderma overlap syndrome-associated autoantigen).

EXOS9_HUMAN
NC score	0.732618 (rank : 6)	θ value	2.27762e-19 (rank : 6)
Query Neighborhood Hits	7	Target Neighborhood Hits	10	Shared Neighborhood Hits	6
SwissProt Accessions	Q06265, Q12883	Gene names	EXOSC9, PMSCL1
Domain Architecture
Description	Exosome complex exonuclease RRP45 (EC 3.1.13.-) (Exosome component 9) (Polymyositis/scleroderma autoantigen 1) (Autoantigen PM/Scl 1) (Polymyositis/scleroderma autoantigen 75 kDa) (PM/Scl-75) (P75 polymyositis-scleroderma overlap syndrome-associated autoantigen).

P3C2A_MOUSE
NC score	0.008697 (rank : 7)	θ value	5.27518 (rank : 7)
Query Neighborhood Hits	7	Target Neighborhood Hits	181	Shared Neighborhood Hits	2
SwissProt Accessions	Q61194, Q61182	Gene names	Pik3c2a, Cpk
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-alpha) (PtdIns-3-kinase C2 alpha) (PI3K-C2alpha) (Cpk-m) (p170).