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Network neighborhood for query Sequence : ESPL1_HUMAN

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ESPL1_HUMAN
SwissProt Accessions	Q14674	Gene names	ESPL1, ESP1, KIAA0165
Domain Architecture
Description	Separin (EC 3.4.22.49) (Separase) (Caspase-like protein ESPL1) (Extra spindle poles-like 1 protein).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ESPL1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	95	Target Neighborhood Hits	95	Shared Neighborhood Hits	95
SwissProt Accessions	Q14674	Gene names	ESPL1, ESP1, KIAA0165
Domain Architecture
Description	Separin (EC 3.4.22.49) (Separase) (Caspase-like protein ESPL1) (Extra spindle poles-like 1 protein).

ESPL1_MOUSE
θ value	0 (rank : 2)	NC score	0.972047 (rank : 2)
Query Neighborhood Hits	95	Target Neighborhood Hits	67	Shared Neighborhood Hits	7
SwissProt Accessions	P60330	Gene names	Espl1, Esp1, Kiaa0165
Domain Architecture
Description	Separin (EC 3.4.22.49) (Separase) (Caspase-like protein ESPL1) (Extra spindle poles-like 1 protein).

GASP1_MOUSE
θ value	0.0330416 (rank : 3)	NC score	0.047049 (rank : 5)
Query Neighborhood Hits	95	Target Neighborhood Hits	169	Shared Neighborhood Hits	6
SwissProt Accessions	Q5U4C1, Q8BKR8, Q8BUN4, Q8BYK9, Q8CHF4, Q8R095	Gene names	Gprasp1, Kiaa0443
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor-associated sorting protein 1 (GASP-1).

BAT2_HUMAN
θ value	0.125558 (rank : 4)	NC score	0.055450 (rank : 4)
Query Neighborhood Hits	95	Target Neighborhood Hits	931	Shared Neighborhood Hits	29
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

FKBP4_MOUSE
θ value	0.279714 (rank : 5)	NC score	0.036604 (rank : 8)
Query Neighborhood Hits	95	Target Neighborhood Hits	100	Shared Neighborhood Hits	4
SwissProt Accessions	P30416, Q3TVC9	Gene names	Fkbp4
Domain Architecture
Description	FK506-binding protein 4 (EC 5.2.1.8) (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) (p59 protein) (HSP-binding immunophilin) (HBI) (FKBP52 protein) (52 kDa FK506-binding protein) (FKBP59).

K1802_MOUSE
θ value	0.365318 (rank : 6)	NC score	0.028524 (rank : 12)
Query Neighborhood Hits	95	Target Neighborhood Hits	1596	Shared Neighborhood Hits	34
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

CO1A1_HUMAN
θ value	0.47712 (rank : 7)	NC score	0.026178 (rank : 16)
Query Neighborhood Hits	95	Target Neighborhood Hits	475	Shared Neighborhood Hits	22
SwissProt Accessions	P02452, P78441, Q13896, Q13902, Q13903, Q14037, Q14992, Q15176, Q15201, Q16050, Q7KZ30, Q7KZ34, Q8IVI5, Q9UML6, Q9UMM7	Gene names	COL1A1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

PNOC_MOUSE
θ value	0.47712 (rank : 8)	NC score	0.060843 (rank : 3)
Query Neighborhood Hits	95	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	Q64387, Q61105, Q61938	Gene names	Pnoc, Npnc1
Domain Architecture
Description	Nociceptin precursor (N23K/N27K) [Contains: Neuropeptide 1; Nociceptin (Orphanin FQ) (PPNOC); Neuropeptide 2].

FKBP4_HUMAN
θ value	0.62314 (rank : 9)	NC score	0.033725 (rank : 9)
Query Neighborhood Hits	95	Target Neighborhood Hits	114	Shared Neighborhood Hits	6
SwissProt Accessions	Q02790, Q9UCP1, Q9UCV7	Gene names	FKBP4
Domain Architecture
Description	FK506-binding protein 4 (EC 5.2.1.8) (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) (p59 protein) (HSP-binding immunophilin) (HBI) (FKBP52 protein) (52 kDa FK506-binding protein) (FKBP59).

KIF1A_HUMAN
θ value	0.62314 (rank : 10)	NC score	0.018212 (rank : 46)
Query Neighborhood Hits	95	Target Neighborhood Hits	240	Shared Neighborhood Hits	11
SwissProt Accessions	Q12756	Gene names	KIF1A, ATSV
Domain Architecture
Description	Kinesin-like protein KIF1A (Axonal transporter of synaptic vesicles).

RIMB1_MOUSE
θ value	0.62314 (rank : 11)	NC score	0.023333 (rank : 28)
Query Neighborhood Hits	95	Target Neighborhood Hits	1376	Shared Neighborhood Hits	28
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

CO1A1_MOUSE
θ value	0.813845 (rank : 12)	NC score	0.025604 (rank : 18)
Query Neighborhood Hits	95	Target Neighborhood Hits	457	Shared Neighborhood Hits	24
SwissProt Accessions	P11087, Q53WT0, Q60635, Q61367, Q61427, Q63919, Q6PCL3, Q810J9	Gene names	Col1a1, Cola1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

CYLN2_HUMAN
θ value	0.813845 (rank : 13)	NC score	0.014310 (rank : 58)
Query Neighborhood Hits	95	Target Neighborhood Hits	1004	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UDT6, O14527, O43611	Gene names	CYLN2, KIAA0291, WBSCR4, WSCR4
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115) (Williams-Beuren syndrome chromosome region 4 protein).

DDX51_HUMAN
θ value	0.813845 (rank : 14)	NC score	0.017790 (rank : 50)
Query Neighborhood Hits	95	Target Neighborhood Hits	332	Shared Neighborhood Hits	15
SwissProt Accessions	Q8N8A6, Q5CZ71, Q8IXK5, Q96ED1	Gene names	DDX51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

GP179_HUMAN
θ value	0.813845 (rank : 15)	NC score	0.033197 (rank : 10)
Query Neighborhood Hits	95	Target Neighborhood Hits	372	Shared Neighborhood Hits	11
SwissProt Accessions	Q6PRD1	Gene names	GPR179, GPR158L1
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 179 precursor (Probable G-protein coupled receptor 158-like 1).

RGS3_HUMAN
θ value	0.813845 (rank : 16)	NC score	0.023789 (rank : 26)
Query Neighborhood Hits	95	Target Neighborhood Hits	1375	Shared Neighborhood Hits	35
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

BSPRY_MOUSE
θ value	1.06291 (rank : 17)	NC score	0.021432 (rank : 32)
Query Neighborhood Hits	95	Target Neighborhood Hits	163	Shared Neighborhood Hits	4
SwissProt Accessions	Q80YW5, Q3TU74, Q8BZF0, Q99KV7, Q9ER70	Gene names	Bspry
Domain Architecture	No domain graphic available
Description	B box and SPRY domain-containing protein.

C8AP2_MOUSE
θ value	1.06291 (rank : 18)	NC score	0.031364 (rank : 11)
Query Neighborhood Hits	95	Target Neighborhood Hits	405	Shared Neighborhood Hits	13
SwissProt Accessions	Q9WUF3, Q9CSW2	Gene names	Casp8ap2, Flash
Domain Architecture	No domain graphic available
Description	CASP8-associated protein 2 (FLICE-associated huge protein).

KIF6_HUMAN
θ value	1.06291 (rank : 19)	NC score	0.017232 (rank : 51)
Query Neighborhood Hits	95	Target Neighborhood Hits	271	Shared Neighborhood Hits	6
SwissProt Accessions	Q6ZMV9, Q2MDE3, Q2MDE4, Q5T8J6, Q6ZWE3, Q86T87, Q8WTV4	Gene names	KIF6, C6orf102
Domain Architecture	No domain graphic available
Description	Kinesin-like protein KIF6.

O10Q1_HUMAN
θ value	1.06291 (rank : 20)	NC score	0.001612 (rank : 95)
Query Neighborhood Hits	95	Target Neighborhood Hits	790	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NGQ4	Gene names	OR10Q1
Domain Architecture
Description	Olfactory receptor 10Q1.

ZFP38_HUMAN
θ value	1.06291 (rank : 21)	NC score	0.006281 (rank : 87)
Query Neighborhood Hits	95	Target Neighborhood Hits	766	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Y5A6, Q9H0B5	Gene names	ZNF38, ZFP38, ZSCAN21
Domain Architecture
Description	Zinc finger protein 38 homolog (Zfp-38) (Zinc finger and SCAN domain- containing protein 21) (NY-REN-21 antigen).

FOXO4_HUMAN
θ value	1.38821 (rank : 22)	NC score	0.020786 (rank : 34)
Query Neighborhood Hits	95	Target Neighborhood Hits	197	Shared Neighborhood Hits	11
SwissProt Accessions	P98177, O43821, Q13720, Q3KPF1, Q8TDK9	Gene names	MLLT7, AFX, AFX1, FOXO4
Domain Architecture
Description	Fork head domain transcription factor AFX1 (Forkhead box protein O4).

MKL1_MOUSE
θ value	1.38821 (rank : 23)	NC score	0.023687 (rank : 27)
Query Neighborhood Hits	95	Target Neighborhood Hits	667	Shared Neighborhood Hits	13
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

NADAP_HUMAN
θ value	1.38821 (rank : 24)	NC score	0.041270 (rank : 7)
Query Neighborhood Hits	95	Target Neighborhood Hits	208	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BWU0, Q4KMT1, Q4KMX0, Q7Z5Q9, Q9NVN2	Gene names	SLC4A1AP, HLC3
Domain Architecture	No domain graphic available
Description	Kanadaptin (Kidney anion exchanger adapter protein) (Solute carrier family 4 anion exchanger member 1 adapter protein) (Lung cancer oncogene 3 protein).

PKHA6_HUMAN
θ value	1.38821 (rank : 25)	NC score	0.024579 (rank : 24)
Query Neighborhood Hits	95	Target Neighborhood Hits	556	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

TITIN_HUMAN
θ value	1.38821 (rank : 26)	NC score	0.006258 (rank : 88)
Query Neighborhood Hits	95	Target Neighborhood Hits	2923	Shared Neighborhood Hits	35
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

ZN263_HUMAN
θ value	1.38821 (rank : 27)	NC score	0.005321 (rank : 90)
Query Neighborhood Hits	95	Target Neighborhood Hits	795	Shared Neighborhood Hits	13
SwissProt Accessions	O14978, O43387, Q96H95	Gene names	ZNF263, FPM315
Domain Architecture
Description	Zinc finger protein 263 (Zinc finger protein FPM315).

FOXB1_HUMAN
θ value	1.81305 (rank : 28)	NC score	0.016146 (rank : 55)
Query Neighborhood Hits	95	Target Neighborhood Hits	121	Shared Neighborhood Hits	4
SwissProt Accessions	Q99853, O60652, O75917	Gene names	FOXB1, FKH5
Domain Architecture
Description	Forkhead box protein B1 (Transcription factor FKH-5).

FOXB1_MOUSE
θ value	1.81305 (rank : 29)	NC score	0.016473 (rank : 53)
Query Neighborhood Hits	95	Target Neighborhood Hits	125	Shared Neighborhood Hits	5
SwissProt Accessions	Q64732, O08753	Gene names	Foxb1, Fkh5, Foxb1a, Foxb1b, Mf3
Domain Architecture
Description	Forkhead box protein B1 (Transcription factor FKH-5).

HUWE1_HUMAN
θ value	1.81305 (rank : 30)	NC score	0.019002 (rank : 38)
Query Neighborhood Hits	95	Target Neighborhood Hits	443	Shared Neighborhood Hits	12
SwissProt Accessions	Q7Z6Z7, O15029, Q4G2Z2, Q5H961, Q6P4D0, Q8NG67, Q9BUI0, Q9HCJ4, Q9NSL6, Q9P0A9	Gene names	HUWE1, KIAA0312, KIAA1578, UREB1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (Mcl-1 ubiquitin ligase E3) (Mule) (ARF-binding protein 1) (ARF-BP1).

DLGP4_HUMAN
θ value	2.36792 (rank : 31)	NC score	0.021291 (rank : 33)
Query Neighborhood Hits	95	Target Neighborhood Hits	90	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y2H0, Q5T2Y4, Q5T2Y5, Q9H137, Q9H138, Q9H1L7	Gene names	DLGAP4, DAP4, KIAA0964
Domain Architecture
Description	Disks large-associated protein 4 (DAP-4) (SAP90/PSD-95-associated protein 4) (SAPAP4) (PSD-95/SAP90-binding protein 4).

GLI2_HUMAN
θ value	2.36792 (rank : 32)	NC score	0.006960 (rank : 85)
Query Neighborhood Hits	95	Target Neighborhood Hits	971	Shared Neighborhood Hits	15
SwissProt Accessions	P10070, O60252, O60253, O60254, O60255, Q15590, Q15591	Gene names	GLI2, THP
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI2 (Tax helper protein).

NSD1_HUMAN
θ value	2.36792 (rank : 33)	NC score	0.022924 (rank : 29)
Query Neighborhood Hits	95	Target Neighborhood Hits	427	Shared Neighborhood Hits	17
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

SRRM1_HUMAN
θ value	2.36792 (rank : 34)	NC score	0.025137 (rank : 19)
Query Neighborhood Hits	95	Target Neighborhood Hits	690	Shared Neighborhood Hits	21
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

ZN397_HUMAN
θ value	2.36792 (rank : 35)	NC score	0.004910 (rank : 93)
Query Neighborhood Hits	95	Target Neighborhood Hits	749	Shared Neighborhood Hits	11
SwissProt Accessions	Q8NF99, Q9BRM2	Gene names	ZNF397, ZSCAN15
Domain Architecture
Description	Zinc finger protein 397 (Zinc finger and SCAN domain-containing protein 15).

ATX7_HUMAN
θ value	3.0926 (rank : 36)	NC score	0.024993 (rank : 22)
Query Neighborhood Hits	95	Target Neighborhood Hits	351	Shared Neighborhood Hits	11
SwissProt Accessions	O15265, O75328, O75329, Q9Y6P8	Gene names	ATXN7, SCA7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein).

BAT2_MOUSE
θ value	3.0926 (rank : 37)	NC score	0.044886 (rank : 6)
Query Neighborhood Hits	95	Target Neighborhood Hits	947	Shared Neighborhood Hits	33
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

MLL4_HUMAN
θ value	3.0926 (rank : 38)	NC score	0.021571 (rank : 31)
Query Neighborhood Hits	95	Target Neighborhood Hits	722	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

SYNJ1_MOUSE
θ value	3.0926 (rank : 39)	NC score	0.018439 (rank : 44)
Query Neighborhood Hits	95	Target Neighborhood Hits	516	Shared Neighborhood Hits	19
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

TRI66_HUMAN
θ value	3.0926 (rank : 40)	NC score	0.024914 (rank : 23)
Query Neighborhood Hits	95	Target Neighborhood Hits	479	Shared Neighborhood Hits	21
SwissProt Accessions	O15016, Q9BQQ4	Gene names	TRIM66, KIAA0298
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

TRI66_MOUSE
θ value	3.0926 (rank : 41)	NC score	0.023865 (rank : 25)
Query Neighborhood Hits	95	Target Neighborhood Hits	491	Shared Neighborhood Hits	19
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

U383_MOUSE
θ value	3.0926 (rank : 42)	NC score	0.025683 (rank : 17)
Query Neighborhood Hits	95	Target Neighborhood Hits	36	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D2Q2, Q3V1K3	Gene names
Domain Architecture	No domain graphic available
Description	Putative methyltransferase UPF0383 (EC 2.1.1.-).

ZN165_HUMAN
θ value	3.0926 (rank : 43)	NC score	0.005460 (rank : 89)
Query Neighborhood Hits	95	Target Neighborhood Hits	734	Shared Neighborhood Hits	11
SwissProt Accessions	P49910	Gene names	ZNF165, ZPF165, ZSCAN7
Domain Architecture
Description	Zinc finger protein 165 (LD65) (Zinc finger and SCAN domain-containing protein 7).

AKAP9_HUMAN
θ value	4.03905 (rank : 44)	NC score	0.016523 (rank : 52)
Query Neighborhood Hits	95	Target Neighborhood Hits	1710	Shared Neighborhood Hits	22
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

HUWE1_MOUSE
θ value	4.03905 (rank : 45)	NC score	0.017809 (rank : 49)
Query Neighborhood Hits	95	Target Neighborhood Hits	406	Shared Neighborhood Hits	11
SwissProt Accessions	Q7TMY8, Q4G2Z1, Q5BMM7, Q6NS61, Q8BNJ7, Q8CFH2, Q8VD14, Q921M5, Q9R0P2	Gene names	Huwe1, Kiaa0312, Ureb1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (E3Histone).

PRG4_HUMAN
θ value	4.03905 (rank : 46)	NC score	0.019494 (rank : 37)
Query Neighborhood Hits	95	Target Neighborhood Hits	764	Shared Neighborhood Hits	27
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

PUR4_HUMAN
θ value	4.03905 (rank : 47)	NC score	0.028284 (rank : 13)
Query Neighborhood Hits	95	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	O15067	Gene names	PFAS, KIAA0361
Domain Architecture
Description	Phosphoribosylformylglycinamidine synthase (EC 6.3.5.3) (FGAM synthase) (FGAMS) (Formylglycinamide ribotide amidotransferase) (FGARAT) (Formylglycinamide ribotide synthetase).

SYN2_MOUSE
θ value	4.03905 (rank : 48)	NC score	0.018545 (rank : 42)
Query Neighborhood Hits	95	Target Neighborhood Hits	183	Shared Neighborhood Hits	12
SwissProt Accessions	Q64332, Q6NZR0, Q9QWV7	Gene names	Syn2
Domain Architecture	No domain graphic available
Description	Synapsin-2 (Synapsin II).

TRAF2_MOUSE
θ value	4.03905 (rank : 49)	NC score	0.025036 (rank : 21)
Query Neighborhood Hits	95	Target Neighborhood Hits	394	Shared Neighborhood Hits	3
SwissProt Accessions	P39429, O54896	Gene names	Traf2
Domain Architecture
Description	TNF receptor-associated factor 2.

WRN_MOUSE
θ value	4.03905 (rank : 50)	NC score	0.027700 (rank : 15)
Query Neighborhood Hits	95	Target Neighborhood Hits	295	Shared Neighborhood Hits	9
SwissProt Accessions	O09053, O09050, Q9JKD4, Q9Z241, Q9Z242	Gene names	Wrn
Domain Architecture
Description	Werner syndrome ATP-dependent helicase homolog (EC 3.6.1.-).

AP3D1_HUMAN
θ value	5.27518 (rank : 51)	NC score	0.017990 (rank : 47)
Query Neighborhood Hits	95	Target Neighborhood Hits	254	Shared Neighborhood Hits	9
SwissProt Accessions	O14617, O00202, O75262, Q59HF5, Q96G11, Q9H3C6	Gene names	AP3D1
Domain Architecture
Description	AP-3 complex subunit delta-1 (Adapter-related protein complex 3 subunit delta-1) (Delta-adaptin 3) (AP-3 complex subunit delta) (Delta-adaptin).

AP3D1_MOUSE
θ value	5.27518 (rank : 52)	NC score	0.017857 (rank : 48)
Query Neighborhood Hits	95	Target Neighborhood Hits	144	Shared Neighborhood Hits	5
SwissProt Accessions	O54774	Gene names	Ap3d1, Ap3d
Domain Architecture	No domain graphic available
Description	AP-3 complex subunit delta-1 (Adapter-related protein complex 3 subunit delta-1) (Delta-adaptin 3) (AP-3 complex subunit delta) (Delta-adaptin) (mBLVR1).

CBX7_HUMAN
θ value	5.27518 (rank : 53)	NC score	0.016203 (rank : 54)
Query Neighborhood Hits	95	Target Neighborhood Hits	48	Shared Neighborhood Hits	3
SwissProt Accessions	O95931, Q86T17	Gene names	CBX7
Domain Architecture
Description	Chromobox protein homolog 7.

CO3A1_HUMAN
θ value	5.27518 (rank : 54)	NC score	0.019871 (rank : 36)
Query Neighborhood Hits	95	Target Neighborhood Hits	452	Shared Neighborhood Hits	21
SwissProt Accessions	P02461, Q15112, Q16403, Q6LDB3, Q6LDJ2, Q6LDJ3, Q7KZ56	Gene names	COL3A1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

CO4A5_HUMAN
θ value	5.27518 (rank : 55)	NC score	0.015310 (rank : 56)
Query Neighborhood Hits	95	Target Neighborhood Hits	383	Shared Neighborhood Hits	23
SwissProt Accessions	P29400, Q16006, Q16126, Q6LD84	Gene names	COL4A5
Domain Architecture
Description	Collagen alpha-5(IV) chain precursor.

COBA2_MOUSE
θ value	5.27518 (rank : 56)	NC score	0.015028 (rank : 57)
Query Neighborhood Hits	95	Target Neighborhood Hits	501	Shared Neighborhood Hits	22
SwissProt Accessions	Q64739, Q61432, Q9Z1W0	Gene names	Col11a2
Domain Architecture
Description	Collagen alpha-2(XI) chain precursor.

CTDP1_HUMAN
θ value	5.27518 (rank : 57)	NC score	0.025071 (rank : 20)
Query Neighborhood Hits	95	Target Neighborhood Hits	416	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Y5B0, Q7Z644, Q96BZ1, Q9Y6F5	Gene names	CTDP1, FCP1
Domain Architecture
Description	RNA polymerase II subunit A C-terminal domain phosphatase (EC 3.1.3.16) (TFIIF-associating CTD phosphatase).

PACS1_MOUSE
θ value	5.27518 (rank : 58)	NC score	0.018629 (rank : 41)
Query Neighborhood Hits	95	Target Neighborhood Hits	87	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K212, Q6P5H8	Gene names	Pacs1
Domain Architecture	No domain graphic available
Description	Phosphofurin acidic cluster sorting protein 1 (PACS-1).

PPE2_MOUSE
θ value	5.27518 (rank : 59)	NC score	0.011087 (rank : 69)
Query Neighborhood Hits	95	Target Neighborhood Hits	112	Shared Neighborhood Hits	3
SwissProt Accessions	O35385	Gene names	Ppef2
Domain Architecture
Description	Serine/threonine-protein phosphatase with EF-hands 2 (EC 3.1.3.16) (PPEF-2).

SELV_HUMAN
θ value	5.27518 (rank : 60)	NC score	0.028135 (rank : 14)
Query Neighborhood Hits	95	Target Neighborhood Hits	118	Shared Neighborhood Hits	8
SwissProt Accessions	P59797	Gene names	SELV
Domain Architecture	No domain graphic available
Description	Selenoprotein V.

TTLL5_HUMAN
θ value	5.27518 (rank : 61)	NC score	0.012617 (rank : 65)
Query Neighborhood Hits	95	Target Neighborhood Hits	141	Shared Neighborhood Hits	4
SwissProt Accessions	Q6EMB2, Q9P1V5, Q9UPZ4	Gene names	TTLL5, KIAA0998, STAMP
Domain Architecture	No domain graphic available
Description	Tubulin--tyrosine ligase-like protein 5 (SRC1 and TIF2-associated modulatory protein).

ZN446_HUMAN
θ value	5.27518 (rank : 62)	NC score	0.007644 (rank : 79)
Query Neighborhood Hits	95	Target Neighborhood Hits	721	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NWS9	Gene names	ZNF446
Domain Architecture	No domain graphic available
Description	Zinc finger protein 446.

AFF4_MOUSE
θ value	6.88961 (rank : 63)	NC score	0.013406 (rank : 60)
Query Neighborhood Hits	95	Target Neighborhood Hits	581	Shared Neighborhood Hits	17
SwissProt Accessions	Q9ESC8, Q8C6K4, Q8C6W3, Q8CCH3	Gene names	Aff4, Alf4
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4.

APXL_HUMAN
θ value	6.88961 (rank : 64)	NC score	0.020778 (rank : 35)
Query Neighborhood Hits	95	Target Neighborhood Hits	553	Shared Neighborhood Hits	20
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

BRWD1_MOUSE
θ value	6.88961 (rank : 65)	NC score	0.007122 (rank : 83)
Query Neighborhood Hits	95	Target Neighborhood Hits	478	Shared Neighborhood Hits	9
SwissProt Accessions	Q921C3, Q921C2	Gene names	Brwd1, Wdr9
Domain Architecture	No domain graphic available
Description	Bromodomain and WD repeat domain-containing protein 1 (WD repeat protein 9).

FOG1_MOUSE
θ value	6.88961 (rank : 66)	NC score	0.009436 (rank : 75)
Query Neighborhood Hits	95	Target Neighborhood Hits	1237	Shared Neighborhood Hits	33
SwissProt Accessions	O35615	Gene names	Zfpm1, Fog, Fog1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

IF4G1_MOUSE
θ value	6.88961 (rank : 67)	NC score	0.018489 (rank : 43)
Query Neighborhood Hits	95	Target Neighborhood Hits	534	Shared Neighborhood Hits	22
SwissProt Accessions	Q6NZJ6, Q6NZN8, Q8BW99	Gene names	Eif4g1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1).

KIF1A_MOUSE
θ value	6.88961 (rank : 68)	NC score	0.013913 (rank : 59)
Query Neighborhood Hits	95	Target Neighborhood Hits	239	Shared Neighborhood Hits	11
SwissProt Accessions	P33173, Q61770	Gene names	Kif1a, Atsv, Kif1
Domain Architecture
Description	Kinesin-like protein KIF1A (Axonal transporter of synaptic vesicles).

KLHL6_MOUSE
θ value	6.88961 (rank : 69)	NC score	0.004046 (rank : 94)
Query Neighborhood Hits	95	Target Neighborhood Hits	186	Shared Neighborhood Hits	2
SwissProt Accessions	Q6V595	Gene names	Klhl6
Domain Architecture	No domain graphic available
Description	Kelch-like protein 6.

RIMB1_HUMAN
θ value	6.88961 (rank : 70)	NC score	0.022632 (rank : 30)
Query Neighborhood Hits	95	Target Neighborhood Hits	1479	Shared Neighborhood Hits	36
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

RUFY1_MOUSE
θ value	6.88961 (rank : 71)	NC score	0.008547 (rank : 78)
Query Neighborhood Hits	95	Target Neighborhood Hits	765	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BIJ7, Q8BKQ4, Q8BL21, Q9EPM6	Gene names	Rufy1, Rabip4
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 1 (Rab4-interacting protein).

S12A5_MOUSE
θ value	6.88961 (rank : 72)	NC score	0.007099 (rank : 84)
Query Neighborhood Hits	95	Target Neighborhood Hits	59	Shared Neighborhood Hits	3
SwissProt Accessions	Q91V14, Q9Z0M7	Gene names	Slc12a5, Kcc2
Domain Architecture
Description	Solute carrier family 12 member 5 (Electroneutral potassium-chloride cotransporter 2) (K-Cl cotransporter 2) (Neuronal K-Cl cotransporter) (mKCC2).

STIM1_HUMAN
θ value	6.88961 (rank : 73)	NC score	0.010623 (rank : 71)
Query Neighborhood Hits	95	Target Neighborhood Hits	665	Shared Neighborhood Hits	11
SwissProt Accessions	Q13586	Gene names	STIM1, GOK
Domain Architecture
Description	Stromal interaction molecule 1 precursor.

SYNE2_HUMAN
θ value	6.88961 (rank : 74)	NC score	0.013266 (rank : 61)
Query Neighborhood Hits	95	Target Neighborhood Hits	1323	Shared Neighborhood Hits	22
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

TAP2_HUMAN
θ value	6.88961 (rank : 75)	NC score	0.005209 (rank : 91)
Query Neighborhood Hits	95	Target Neighborhood Hits	103	Shared Neighborhood Hits	2
SwissProt Accessions	Q03519, Q9UQ83	Gene names	TAP2, ABCB3, PSF2, RING11, Y1
Domain Architecture
Description	Antigen peptide transporter 2 (APT2) (ATP-binding cassette sub-family B member 3) (Peptide transporter TAP2) (Peptide transporter PSF2) (Peptide supply factor 2) (PSF-2) (Peptide transporter involved in antigen processing 2).

TULP4_HUMAN
θ value	6.88961 (rank : 76)	NC score	0.018642 (rank : 40)
Query Neighborhood Hits	95	Target Neighborhood Hits	426	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NRJ4, Q9HD22, Q9P2F0	Gene names	TULP4, KIAA1397, TUSP
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

TULP4_MOUSE
θ value	6.88961 (rank : 77)	NC score	0.018761 (rank : 39)
Query Neighborhood Hits	95	Target Neighborhood Hits	247	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JIL5, Q8CA75, Q922C2	Gene names	Tulp4, Tusp
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

WDHD1_MOUSE
θ value	6.88961 (rank : 78)	NC score	0.009164 (rank : 76)
Query Neighborhood Hits	95	Target Neighborhood Hits	414	Shared Neighborhood Hits	5
SwissProt Accessions	P59328, Q6P408	Gene names	Wdhd1, And1
Domain Architecture	No domain graphic available
Description	WD repeat and HMG-box DNA-binding protein 1 (Acidic nucleoplasmic DNA- binding protein 1) (And-1).

ZN193_HUMAN
θ value	6.88961 (rank : 79)	NC score	0.004974 (rank : 92)
Query Neighborhood Hits	95	Target Neighborhood Hits	717	Shared Neighborhood Hits	11
SwissProt Accessions	O15535	Gene names	ZNF193, ZSCAN9
Domain Architecture
Description	Zinc finger protein 193 (PRD51) (Zinc finger and SCAN domain- containing protein 9).

ZN687_MOUSE
θ value	6.88961 (rank : 80)	NC score	0.007193 (rank : 82)
Query Neighborhood Hits	95	Target Neighborhood Hits	913	Shared Neighborhood Hits	17
SwissProt Accessions	Q9D2D7, Q6PAP3, Q6ZPQ9	Gene names	Znf687, Kiaa1441, Zfp687
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

ARHG1_MOUSE
θ value	8.99809 (rank : 81)	NC score	0.009775 (rank : 74)
Query Neighborhood Hits	95	Target Neighborhood Hits	266	Shared Neighborhood Hits	14
SwissProt Accessions	Q61210, O89074, Q80YE8, Q80YE9, Q91VL3	Gene names	Arhgef1, Lbcl2, Lsc
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (Lymphoid blast crisis-like 2) (Lbc's second cousin).

BAT3_MOUSE
θ value	8.99809 (rank : 82)	NC score	0.018271 (rank : 45)
Query Neighborhood Hits	95	Target Neighborhood Hits	518	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Z1R2, Q8SNA3	Gene names	Bat3
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3).

BUB1B_HUMAN
θ value	8.99809 (rank : 83)	NC score	0.011030 (rank : 70)
Query Neighborhood Hits	95	Target Neighborhood Hits	208	Shared Neighborhood Hits	3
SwissProt Accessions	O60566, O60501, O60627, O60758, O75389, Q96KM4	Gene names	BUB1B, BUBR1, MAD3L
Domain Architecture
Description	Mitotic checkpoint serine/threonine-protein kinase BUB1 beta (EC 2.7.11.1) (hBUBR1) (MAD3/BUB1-related protein kinase) (Mitotic checkpoint kinase MAD3L) (SSK1).

CABP4_HUMAN
θ value	8.99809 (rank : 84)	NC score	0.007211 (rank : 81)
Query Neighborhood Hits	95	Target Neighborhood Hits	250	Shared Neighborhood Hits	10
SwissProt Accessions	P57796, Q8N4Z2, Q8WWY5	Gene names	CABP4
Domain Architecture
Description	Calcium-binding protein 4 (CaBP4).

COEA1_MOUSE
θ value	8.99809 (rank : 85)	NC score	0.008956 (rank : 77)
Query Neighborhood Hits	95	Target Neighborhood Hits	402	Shared Neighborhood Hits	14
SwissProt Accessions	Q80X19, Q8C6X3, Q9WV05	Gene names	Col14a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor.

DLEC1_HUMAN
θ value	8.99809 (rank : 86)	NC score	0.013154 (rank : 63)
Query Neighborhood Hits	95	Target Neighborhood Hits	44	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y238, Q9NSW0, Q9NTG5	Gene names	DLEC1, DLC1
Domain Architecture	No domain graphic available
Description	Deleted in lung and esophageal cancer protein 1 (Deleted in lung cancer protein 1) (DLC-1).

HIP1_HUMAN
θ value	8.99809 (rank : 87)	NC score	0.006536 (rank : 86)
Query Neighborhood Hits	95	Target Neighborhood Hits	1016	Shared Neighborhood Hits	16
SwissProt Accessions	O00291, O00328, Q8TDL4	Gene names	HIP1
Domain Architecture
Description	Huntingtin-interacting protein 1 (HIP-I).

JIP1_HUMAN
θ value	8.99809 (rank : 88)	NC score	0.012780 (rank : 64)
Query Neighborhood Hits	95	Target Neighborhood Hits	271	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UQF2, O43407	Gene names	MAPK8IP1, IB1, JIP1
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain 1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

LBN_HUMAN
θ value	8.99809 (rank : 89)	NC score	0.010244 (rank : 72)
Query Neighborhood Hits	95	Target Neighborhood Hits	308	Shared Neighborhood Hits	7
SwissProt Accessions	Q86UK5, Q86YT3, Q86YT4, Q8NG49	Gene names	EVC2, LBN
Domain Architecture	No domain graphic available
Description	Limbin.

LYST_MOUSE
θ value	8.99809 (rank : 90)	NC score	0.011160 (rank : 68)
Query Neighborhood Hits	95	Target Neighborhood Hits	286	Shared Neighborhood Hits	9
SwissProt Accessions	P97412, Q62403, Q8VBS6	Gene names	Lyst, Bg, Chs1
Domain Architecture
Description	Lysosomal-trafficking regulator (Beige protein) (CHS1 homolog).

NIBL_HUMAN
θ value	8.99809 (rank : 91)	NC score	0.013254 (rank : 62)
Query Neighborhood Hits	95	Target Neighborhood Hits	61	Shared Neighborhood Hits	5
SwissProt Accessions	Q96TA1, Q9BUS2, Q9NT35	Gene names	C9orf88
Domain Architecture	No domain graphic available
Description	Niban-like protein (Meg-3).

PKHG4_HUMAN
θ value	8.99809 (rank : 92)	NC score	0.012289 (rank : 67)
Query Neighborhood Hits	95	Target Neighborhood Hits	200	Shared Neighborhood Hits	12
SwissProt Accessions	Q58EX7, Q4G0J8, Q4H485, Q56A69, Q9H7K4, Q9UFW0	Gene names	PLEKHG4, PRTPHN1
Domain Architecture	No domain graphic available
Description	Puratrophin-1 (Pleckstrin homology domain-containing family G member 4) (Purkinje cell atrophy-associated protein 1).

SPTN5_HUMAN
θ value	8.99809 (rank : 93)	NC score	0.007430 (rank : 80)
Query Neighborhood Hits	95	Target Neighborhood Hits	674	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NRC6	Gene names	SPTBN5, SPTBN4
Domain Architecture
Description	Spectrin beta chain, brain 4 (Spectrin, non-erythroid beta chain 4) (Beta-V spectrin) (BSPECV).

TB22A_MOUSE
θ value	8.99809 (rank : 94)	NC score	0.009870 (rank : 73)
Query Neighborhood Hits	95	Target Neighborhood Hits	42	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R5A6, Q3U268, Q3U3T0, Q8CA49	Gene names	Tbc1d22a, D15Ertd781e
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 22A.

ZCH11_HUMAN
θ value	8.99809 (rank : 95)	NC score	0.012482 (rank : 66)
Query Neighborhood Hits	95	Target Neighborhood Hits	278	Shared Neighborhood Hits	11
SwissProt Accessions	Q5TAX3, Q12764, Q5TAX4, Q86XZ3	Gene names	ZCCHC11, KIAA0191
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 11.

Hits sorted by NC score

ESPL1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	95	Target Neighborhood Hits	95	Shared Neighborhood Hits	95
SwissProt Accessions	Q14674	Gene names	ESPL1, ESP1, KIAA0165
Domain Architecture
Description	Separin (EC 3.4.22.49) (Separase) (Caspase-like protein ESPL1) (Extra spindle poles-like 1 protein).

ESPL1_MOUSE
NC score	0.972047 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	95	Target Neighborhood Hits	67	Shared Neighborhood Hits	7
SwissProt Accessions	P60330	Gene names	Espl1, Esp1, Kiaa0165
Domain Architecture
Description	Separin (EC 3.4.22.49) (Separase) (Caspase-like protein ESPL1) (Extra spindle poles-like 1 protein).

PNOC_MOUSE
NC score	0.060843 (rank : 3)	θ value	0.47712 (rank : 8)
Query Neighborhood Hits	95	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	Q64387, Q61105, Q61938	Gene names	Pnoc, Npnc1
Domain Architecture
Description	Nociceptin precursor (N23K/N27K) [Contains: Neuropeptide 1; Nociceptin (Orphanin FQ) (PPNOC); Neuropeptide 2].

BAT2_HUMAN
NC score	0.055450 (rank : 4)	θ value	0.125558 (rank : 4)
Query Neighborhood Hits	95	Target Neighborhood Hits	931	Shared Neighborhood Hits	29
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

GASP1_MOUSE
NC score	0.047049 (rank : 5)	θ value	0.0330416 (rank : 3)
Query Neighborhood Hits	95	Target Neighborhood Hits	169	Shared Neighborhood Hits	6
SwissProt Accessions	Q5U4C1, Q8BKR8, Q8BUN4, Q8BYK9, Q8CHF4, Q8R095	Gene names	Gprasp1, Kiaa0443
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor-associated sorting protein 1 (GASP-1).

BAT2_MOUSE
NC score	0.044886 (rank : 6)	θ value	3.0926 (rank : 37)
Query Neighborhood Hits	95	Target Neighborhood Hits	947	Shared Neighborhood Hits	33
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

NADAP_HUMAN
NC score	0.041270 (rank : 7)	θ value	1.38821 (rank : 24)
Query Neighborhood Hits	95	Target Neighborhood Hits	208	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BWU0, Q4KMT1, Q4KMX0, Q7Z5Q9, Q9NVN2	Gene names	SLC4A1AP, HLC3
Domain Architecture	No domain graphic available
Description	Kanadaptin (Kidney anion exchanger adapter protein) (Solute carrier family 4 anion exchanger member 1 adapter protein) (Lung cancer oncogene 3 protein).

FKBP4_MOUSE
NC score	0.036604 (rank : 8)	θ value	0.279714 (rank : 5)
Query Neighborhood Hits	95	Target Neighborhood Hits	100	Shared Neighborhood Hits	4
SwissProt Accessions	P30416, Q3TVC9	Gene names	Fkbp4
Domain Architecture
Description	FK506-binding protein 4 (EC 5.2.1.8) (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) (p59 protein) (HSP-binding immunophilin) (HBI) (FKBP52 protein) (52 kDa FK506-binding protein) (FKBP59).

FKBP4_HUMAN
NC score	0.033725 (rank : 9)	θ value	0.62314 (rank : 9)
Query Neighborhood Hits	95	Target Neighborhood Hits	114	Shared Neighborhood Hits	6
SwissProt Accessions	Q02790, Q9UCP1, Q9UCV7	Gene names	FKBP4
Domain Architecture
Description	FK506-binding protein 4 (EC 5.2.1.8) (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) (p59 protein) (HSP-binding immunophilin) (HBI) (FKBP52 protein) (52 kDa FK506-binding protein) (FKBP59).

GP179_HUMAN
NC score	0.033197 (rank : 10)	θ value	0.813845 (rank : 15)
Query Neighborhood Hits	95	Target Neighborhood Hits	372	Shared Neighborhood Hits	11
SwissProt Accessions	Q6PRD1	Gene names	GPR179, GPR158L1
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 179 precursor (Probable G-protein coupled receptor 158-like 1).

C8AP2_MOUSE
NC score	0.031364 (rank : 11)	θ value	1.06291 (rank : 18)
Query Neighborhood Hits	95	Target Neighborhood Hits	405	Shared Neighborhood Hits	13
SwissProt Accessions	Q9WUF3, Q9CSW2	Gene names	Casp8ap2, Flash
Domain Architecture	No domain graphic available
Description	CASP8-associated protein 2 (FLICE-associated huge protein).

K1802_MOUSE
NC score	0.028524 (rank : 12)	θ value	0.365318 (rank : 6)
Query Neighborhood Hits	95	Target Neighborhood Hits	1596	Shared Neighborhood Hits	34
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

PUR4_HUMAN
NC score	0.028284 (rank : 13)	θ value	4.03905 (rank : 47)
Query Neighborhood Hits	95	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	O15067	Gene names	PFAS, KIAA0361
Domain Architecture
Description	Phosphoribosylformylglycinamidine synthase (EC 6.3.5.3) (FGAM synthase) (FGAMS) (Formylglycinamide ribotide amidotransferase) (FGARAT) (Formylglycinamide ribotide synthetase).

SELV_HUMAN
NC score	0.028135 (rank : 14)	θ value	5.27518 (rank : 60)
Query Neighborhood Hits	95	Target Neighborhood Hits	118	Shared Neighborhood Hits	8
SwissProt Accessions	P59797	Gene names	SELV
Domain Architecture	No domain graphic available
Description	Selenoprotein V.

WRN_MOUSE
NC score	0.027700 (rank : 15)	θ value	4.03905 (rank : 50)
Query Neighborhood Hits	95	Target Neighborhood Hits	295	Shared Neighborhood Hits	9
SwissProt Accessions	O09053, O09050, Q9JKD4, Q9Z241, Q9Z242	Gene names	Wrn
Domain Architecture
Description	Werner syndrome ATP-dependent helicase homolog (EC 3.6.1.-).

CO1A1_HUMAN
NC score	0.026178 (rank : 16)	θ value	0.47712 (rank : 7)
Query Neighborhood Hits	95	Target Neighborhood Hits	475	Shared Neighborhood Hits	22
SwissProt Accessions	P02452, P78441, Q13896, Q13902, Q13903, Q14037, Q14992, Q15176, Q15201, Q16050, Q7KZ30, Q7KZ34, Q8IVI5, Q9UML6, Q9UMM7	Gene names	COL1A1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

U383_MOUSE
NC score	0.025683 (rank : 17)	θ value	3.0926 (rank : 42)
Query Neighborhood Hits	95	Target Neighborhood Hits	36	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D2Q2, Q3V1K3	Gene names
Domain Architecture	No domain graphic available
Description	Putative methyltransferase UPF0383 (EC 2.1.1.-).

CO1A1_MOUSE
NC score	0.025604 (rank : 18)	θ value	0.813845 (rank : 12)
Query Neighborhood Hits	95	Target Neighborhood Hits	457	Shared Neighborhood Hits	24
SwissProt Accessions	P11087, Q53WT0, Q60635, Q61367, Q61427, Q63919, Q6PCL3, Q810J9	Gene names	Col1a1, Cola1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

SRRM1_HUMAN
NC score	0.025137 (rank : 19)	θ value	2.36792 (rank : 34)
Query Neighborhood Hits	95	Target Neighborhood Hits	690	Shared Neighborhood Hits	21
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

CTDP1_HUMAN
NC score	0.025071 (rank : 20)	θ value	5.27518 (rank : 57)
Query Neighborhood Hits	95	Target Neighborhood Hits	416	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Y5B0, Q7Z644, Q96BZ1, Q9Y6F5	Gene names	CTDP1, FCP1
Domain Architecture
Description	RNA polymerase II subunit A C-terminal domain phosphatase (EC 3.1.3.16) (TFIIF-associating CTD phosphatase).

TRAF2_MOUSE
NC score	0.025036 (rank : 21)	θ value	4.03905 (rank : 49)
Query Neighborhood Hits	95	Target Neighborhood Hits	394	Shared Neighborhood Hits	3
SwissProt Accessions	P39429, O54896	Gene names	Traf2
Domain Architecture
Description	TNF receptor-associated factor 2.

ATX7_HUMAN
NC score	0.024993 (rank : 22)	θ value	3.0926 (rank : 36)
Query Neighborhood Hits	95	Target Neighborhood Hits	351	Shared Neighborhood Hits	11
SwissProt Accessions	O15265, O75328, O75329, Q9Y6P8	Gene names	ATXN7, SCA7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein).

TRI66_HUMAN
NC score	0.024914 (rank : 23)	θ value	3.0926 (rank : 40)
Query Neighborhood Hits	95	Target Neighborhood Hits	479	Shared Neighborhood Hits	21
SwissProt Accessions	O15016, Q9BQQ4	Gene names	TRIM66, KIAA0298
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

PKHA6_HUMAN
NC score	0.024579 (rank : 24)	θ value	1.38821 (rank : 25)
Query Neighborhood Hits	95	Target Neighborhood Hits	556	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

TRI66_MOUSE
NC score	0.023865 (rank : 25)	θ value	3.0926 (rank : 41)
Query Neighborhood Hits	95	Target Neighborhood Hits	491	Shared Neighborhood Hits	19
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

RGS3_HUMAN
NC score	0.023789 (rank : 26)	θ value	0.813845 (rank : 16)
Query Neighborhood Hits	95	Target Neighborhood Hits	1375	Shared Neighborhood Hits	35
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

MKL1_MOUSE
NC score	0.023687 (rank : 27)	θ value	1.38821 (rank : 23)
Query Neighborhood Hits	95	Target Neighborhood Hits	667	Shared Neighborhood Hits	13
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

RIMB1_MOUSE
NC score	0.023333 (rank : 28)	θ value	0.62314 (rank : 11)
Query Neighborhood Hits	95	Target Neighborhood Hits	1376	Shared Neighborhood Hits	28
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

NSD1_HUMAN
NC score	0.022924 (rank : 29)	θ value	2.36792 (rank : 33)
Query Neighborhood Hits	95	Target Neighborhood Hits	427	Shared Neighborhood Hits	17
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

RIMB1_HUMAN
NC score	0.022632 (rank : 30)	θ value	6.88961 (rank : 70)
Query Neighborhood Hits	95	Target Neighborhood Hits	1479	Shared Neighborhood Hits	36
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

MLL4_HUMAN
NC score	0.021571 (rank : 31)	θ value	3.0926 (rank : 38)
Query Neighborhood Hits	95	Target Neighborhood Hits	722	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

BSPRY_MOUSE
NC score	0.021432 (rank : 32)	θ value	1.06291 (rank : 17)
Query Neighborhood Hits	95	Target Neighborhood Hits	163	Shared Neighborhood Hits	4
SwissProt Accessions	Q80YW5, Q3TU74, Q8BZF0, Q99KV7, Q9ER70	Gene names	Bspry
Domain Architecture	No domain graphic available
Description	B box and SPRY domain-containing protein.

DLGP4_HUMAN
NC score	0.021291 (rank : 33)	θ value	2.36792 (rank : 31)
Query Neighborhood Hits	95	Target Neighborhood Hits	90	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y2H0, Q5T2Y4, Q5T2Y5, Q9H137, Q9H138, Q9H1L7	Gene names	DLGAP4, DAP4, KIAA0964
Domain Architecture
Description	Disks large-associated protein 4 (DAP-4) (SAP90/PSD-95-associated protein 4) (SAPAP4) (PSD-95/SAP90-binding protein 4).

FOXO4_HUMAN
NC score	0.020786 (rank : 34)	θ value	1.38821 (rank : 22)
Query Neighborhood Hits	95	Target Neighborhood Hits	197	Shared Neighborhood Hits	11
SwissProt Accessions	P98177, O43821, Q13720, Q3KPF1, Q8TDK9	Gene names	MLLT7, AFX, AFX1, FOXO4
Domain Architecture
Description	Fork head domain transcription factor AFX1 (Forkhead box protein O4).

APXL_HUMAN
NC score	0.020778 (rank : 35)	θ value	6.88961 (rank : 64)
Query Neighborhood Hits	95	Target Neighborhood Hits	553	Shared Neighborhood Hits	20
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

CO3A1_HUMAN
NC score	0.019871 (rank : 36)	θ value	5.27518 (rank : 54)
Query Neighborhood Hits	95	Target Neighborhood Hits	452	Shared Neighborhood Hits	21
SwissProt Accessions	P02461, Q15112, Q16403, Q6LDB3, Q6LDJ2, Q6LDJ3, Q7KZ56	Gene names	COL3A1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

PRG4_HUMAN
NC score	0.019494 (rank : 37)	θ value	4.03905 (rank : 46)
Query Neighborhood Hits	95	Target Neighborhood Hits	764	Shared Neighborhood Hits	27
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

HUWE1_HUMAN
NC score	0.019002 (rank : 38)	θ value	1.81305 (rank : 30)
Query Neighborhood Hits	95	Target Neighborhood Hits	443	Shared Neighborhood Hits	12
SwissProt Accessions	Q7Z6Z7, O15029, Q4G2Z2, Q5H961, Q6P4D0, Q8NG67, Q9BUI0, Q9HCJ4, Q9NSL6, Q9P0A9	Gene names	HUWE1, KIAA0312, KIAA1578, UREB1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (Mcl-1 ubiquitin ligase E3) (Mule) (ARF-binding protein 1) (ARF-BP1).

TULP4_MOUSE
NC score	0.018761 (rank : 39)	θ value	6.88961 (rank : 77)
Query Neighborhood Hits	95	Target Neighborhood Hits	247	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JIL5, Q8CA75, Q922C2	Gene names	Tulp4, Tusp
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

TULP4_HUMAN
NC score	0.018642 (rank : 40)	θ value	6.88961 (rank : 76)
Query Neighborhood Hits	95	Target Neighborhood Hits	426	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NRJ4, Q9HD22, Q9P2F0	Gene names	TULP4, KIAA1397, TUSP
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

PACS1_MOUSE
NC score	0.018629 (rank : 41)	θ value	5.27518 (rank : 58)
Query Neighborhood Hits	95	Target Neighborhood Hits	87	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K212, Q6P5H8	Gene names	Pacs1
Domain Architecture	No domain graphic available
Description	Phosphofurin acidic cluster sorting protein 1 (PACS-1).

SYN2_MOUSE
NC score	0.018545 (rank : 42)	θ value	4.03905 (rank : 48)
Query Neighborhood Hits	95	Target Neighborhood Hits	183	Shared Neighborhood Hits	12
SwissProt Accessions	Q64332, Q6NZR0, Q9QWV7	Gene names	Syn2
Domain Architecture	No domain graphic available
Description	Synapsin-2 (Synapsin II).

IF4G1_MOUSE
NC score	0.018489 (rank : 43)	θ value	6.88961 (rank : 67)
Query Neighborhood Hits	95	Target Neighborhood Hits	534	Shared Neighborhood Hits	22
SwissProt Accessions	Q6NZJ6, Q6NZN8, Q8BW99	Gene names	Eif4g1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1).

SYNJ1_MOUSE
NC score	0.018439 (rank : 44)	θ value	3.0926 (rank : 39)
Query Neighborhood Hits	95	Target Neighborhood Hits	516	Shared Neighborhood Hits	19
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

BAT3_MOUSE
NC score	0.018271 (rank : 45)	θ value	8.99809 (rank : 82)
Query Neighborhood Hits	95	Target Neighborhood Hits	518	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Z1R2, Q8SNA3	Gene names	Bat3
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3).

KIF1A_HUMAN
NC score	0.018212 (rank : 46)	θ value	0.62314 (rank : 10)
Query Neighborhood Hits	95	Target Neighborhood Hits	240	Shared Neighborhood Hits	11
SwissProt Accessions	Q12756	Gene names	KIF1A, ATSV
Domain Architecture
Description	Kinesin-like protein KIF1A (Axonal transporter of synaptic vesicles).

AP3D1_HUMAN
NC score	0.017990 (rank : 47)	θ value	5.27518 (rank : 51)
Query Neighborhood Hits	95	Target Neighborhood Hits	254	Shared Neighborhood Hits	9
SwissProt Accessions	O14617, O00202, O75262, Q59HF5, Q96G11, Q9H3C6	Gene names	AP3D1
Domain Architecture
Description	AP-3 complex subunit delta-1 (Adapter-related protein complex 3 subunit delta-1) (Delta-adaptin 3) (AP-3 complex subunit delta) (Delta-adaptin).

AP3D1_MOUSE
NC score	0.017857 (rank : 48)	θ value	5.27518 (rank : 52)
Query Neighborhood Hits	95	Target Neighborhood Hits	144	Shared Neighborhood Hits	5
SwissProt Accessions	O54774	Gene names	Ap3d1, Ap3d
Domain Architecture	No domain graphic available
Description	AP-3 complex subunit delta-1 (Adapter-related protein complex 3 subunit delta-1) (Delta-adaptin 3) (AP-3 complex subunit delta) (Delta-adaptin) (mBLVR1).

HUWE1_MOUSE
NC score	0.017809 (rank : 49)	θ value	4.03905 (rank : 45)
Query Neighborhood Hits	95	Target Neighborhood Hits	406	Shared Neighborhood Hits	11
SwissProt Accessions	Q7TMY8, Q4G2Z1, Q5BMM7, Q6NS61, Q8BNJ7, Q8CFH2, Q8VD14, Q921M5, Q9R0P2	Gene names	Huwe1, Kiaa0312, Ureb1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (E3Histone).

DDX51_HUMAN
NC score	0.017790 (rank : 50)	θ value	0.813845 (rank : 14)
Query Neighborhood Hits	95	Target Neighborhood Hits	332	Shared Neighborhood Hits	15
SwissProt Accessions	Q8N8A6, Q5CZ71, Q8IXK5, Q96ED1	Gene names	DDX51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

KIF6_HUMAN
NC score	0.017232 (rank : 51)	θ value	1.06291 (rank : 19)
Query Neighborhood Hits	95	Target Neighborhood Hits	271	Shared Neighborhood Hits	6
SwissProt Accessions	Q6ZMV9, Q2MDE3, Q2MDE4, Q5T8J6, Q6ZWE3, Q86T87, Q8WTV4	Gene names	KIF6, C6orf102
Domain Architecture	No domain graphic available
Description	Kinesin-like protein KIF6.

AKAP9_HUMAN
NC score	0.016523 (rank : 52)	θ value	4.03905 (rank : 44)
Query Neighborhood Hits	95	Target Neighborhood Hits	1710	Shared Neighborhood Hits	22
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

FOXB1_MOUSE
NC score	0.016473 (rank : 53)	θ value	1.81305 (rank : 29)
Query Neighborhood Hits	95	Target Neighborhood Hits	125	Shared Neighborhood Hits	5
SwissProt Accessions	Q64732, O08753	Gene names	Foxb1, Fkh5, Foxb1a, Foxb1b, Mf3
Domain Architecture
Description	Forkhead box protein B1 (Transcription factor FKH-5).

CBX7_HUMAN
NC score	0.016203 (rank : 54)	θ value	5.27518 (rank : 53)
Query Neighborhood Hits	95	Target Neighborhood Hits	48	Shared Neighborhood Hits	3
SwissProt Accessions	O95931, Q86T17	Gene names	CBX7
Domain Architecture
Description	Chromobox protein homolog 7.

FOXB1_HUMAN
NC score	0.016146 (rank : 55)	θ value	1.81305 (rank : 28)
Query Neighborhood Hits	95	Target Neighborhood Hits	121	Shared Neighborhood Hits	4
SwissProt Accessions	Q99853, O60652, O75917	Gene names	FOXB1, FKH5
Domain Architecture
Description	Forkhead box protein B1 (Transcription factor FKH-5).

CO4A5_HUMAN
NC score	0.015310 (rank : 56)	θ value	5.27518 (rank : 55)
Query Neighborhood Hits	95	Target Neighborhood Hits	383	Shared Neighborhood Hits	23
SwissProt Accessions	P29400, Q16006, Q16126, Q6LD84	Gene names	COL4A5
Domain Architecture
Description	Collagen alpha-5(IV) chain precursor.

COBA2_MOUSE
NC score	0.015028 (rank : 57)	θ value	5.27518 (rank : 56)
Query Neighborhood Hits	95	Target Neighborhood Hits	501	Shared Neighborhood Hits	22
SwissProt Accessions	Q64739, Q61432, Q9Z1W0	Gene names	Col11a2
Domain Architecture
Description	Collagen alpha-2(XI) chain precursor.

CYLN2_HUMAN
NC score	0.014310 (rank : 58)	θ value	0.813845 (rank : 13)
Query Neighborhood Hits	95	Target Neighborhood Hits	1004	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UDT6, O14527, O43611	Gene names	CYLN2, KIAA0291, WBSCR4, WSCR4
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115) (Williams-Beuren syndrome chromosome region 4 protein).

KIF1A_MOUSE
NC score	0.013913 (rank : 59)	θ value	6.88961 (rank : 68)
Query Neighborhood Hits	95	Target Neighborhood Hits	239	Shared Neighborhood Hits	11
SwissProt Accessions	P33173, Q61770	Gene names	Kif1a, Atsv, Kif1
Domain Architecture
Description	Kinesin-like protein KIF1A (Axonal transporter of synaptic vesicles).

AFF4_MOUSE
NC score	0.013406 (rank : 60)	θ value	6.88961 (rank : 63)
Query Neighborhood Hits	95	Target Neighborhood Hits	581	Shared Neighborhood Hits	17
SwissProt Accessions	Q9ESC8, Q8C6K4, Q8C6W3, Q8CCH3	Gene names	Aff4, Alf4
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4.

SYNE2_HUMAN
NC score	0.013266 (rank : 61)	θ value	6.88961 (rank : 74)
Query Neighborhood Hits	95	Target Neighborhood Hits	1323	Shared Neighborhood Hits	22
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

NIBL_HUMAN
NC score	0.013254 (rank : 62)	θ value	8.99809 (rank : 91)
Query Neighborhood Hits	95	Target Neighborhood Hits	61	Shared Neighborhood Hits	5
SwissProt Accessions	Q96TA1, Q9BUS2, Q9NT35	Gene names	C9orf88
Domain Architecture	No domain graphic available
Description	Niban-like protein (Meg-3).

DLEC1_HUMAN
NC score	0.013154 (rank : 63)	θ value	8.99809 (rank : 86)
Query Neighborhood Hits	95	Target Neighborhood Hits	44	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y238, Q9NSW0, Q9NTG5	Gene names	DLEC1, DLC1
Domain Architecture	No domain graphic available
Description	Deleted in lung and esophageal cancer protein 1 (Deleted in lung cancer protein 1) (DLC-1).

JIP1_HUMAN
NC score	0.012780 (rank : 64)	θ value	8.99809 (rank : 88)
Query Neighborhood Hits	95	Target Neighborhood Hits	271	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UQF2, O43407	Gene names	MAPK8IP1, IB1, JIP1
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain 1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

TTLL5_HUMAN
NC score	0.012617 (rank : 65)	θ value	5.27518 (rank : 61)
Query Neighborhood Hits	95	Target Neighborhood Hits	141	Shared Neighborhood Hits	4
SwissProt Accessions	Q6EMB2, Q9P1V5, Q9UPZ4	Gene names	TTLL5, KIAA0998, STAMP
Domain Architecture	No domain graphic available
Description	Tubulin--tyrosine ligase-like protein 5 (SRC1 and TIF2-associated modulatory protein).

ZCH11_HUMAN
NC score	0.012482 (rank : 66)	θ value	8.99809 (rank : 95)
Query Neighborhood Hits	95	Target Neighborhood Hits	278	Shared Neighborhood Hits	11
SwissProt Accessions	Q5TAX3, Q12764, Q5TAX4, Q86XZ3	Gene names	ZCCHC11, KIAA0191
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 11.

PKHG4_HUMAN
NC score	0.012289 (rank : 67)	θ value	8.99809 (rank : 92)
Query Neighborhood Hits	95	Target Neighborhood Hits	200	Shared Neighborhood Hits	12
SwissProt Accessions	Q58EX7, Q4G0J8, Q4H485, Q56A69, Q9H7K4, Q9UFW0	Gene names	PLEKHG4, PRTPHN1
Domain Architecture	No domain graphic available
Description	Puratrophin-1 (Pleckstrin homology domain-containing family G member 4) (Purkinje cell atrophy-associated protein 1).

LYST_MOUSE
NC score	0.011160 (rank : 68)	θ value	8.99809 (rank : 90)
Query Neighborhood Hits	95	Target Neighborhood Hits	286	Shared Neighborhood Hits	9
SwissProt Accessions	P97412, Q62403, Q8VBS6	Gene names	Lyst, Bg, Chs1
Domain Architecture
Description	Lysosomal-trafficking regulator (Beige protein) (CHS1 homolog).

PPE2_MOUSE
NC score	0.011087 (rank : 69)	θ value	5.27518 (rank : 59)
Query Neighborhood Hits	95	Target Neighborhood Hits	112	Shared Neighborhood Hits	3
SwissProt Accessions	O35385	Gene names	Ppef2
Domain Architecture
Description	Serine/threonine-protein phosphatase with EF-hands 2 (EC 3.1.3.16) (PPEF-2).

BUB1B_HUMAN
NC score	0.011030 (rank : 70)	θ value	8.99809 (rank : 83)
Query Neighborhood Hits	95	Target Neighborhood Hits	208	Shared Neighborhood Hits	3
SwissProt Accessions	O60566, O60501, O60627, O60758, O75389, Q96KM4	Gene names	BUB1B, BUBR1, MAD3L
Domain Architecture
Description	Mitotic checkpoint serine/threonine-protein kinase BUB1 beta (EC 2.7.11.1) (hBUBR1) (MAD3/BUB1-related protein kinase) (Mitotic checkpoint kinase MAD3L) (SSK1).

STIM1_HUMAN
NC score	0.010623 (rank : 71)	θ value	6.88961 (rank : 73)
Query Neighborhood Hits	95	Target Neighborhood Hits	665	Shared Neighborhood Hits	11
SwissProt Accessions	Q13586	Gene names	STIM1, GOK
Domain Architecture
Description	Stromal interaction molecule 1 precursor.

LBN_HUMAN
NC score	0.010244 (rank : 72)	θ value	8.99809 (rank : 89)
Query Neighborhood Hits	95	Target Neighborhood Hits	308	Shared Neighborhood Hits	7
SwissProt Accessions	Q86UK5, Q86YT3, Q86YT4, Q8NG49	Gene names	EVC2, LBN
Domain Architecture	No domain graphic available
Description	Limbin.

TB22A_MOUSE
NC score	0.009870 (rank : 73)	θ value	8.99809 (rank : 94)
Query Neighborhood Hits	95	Target Neighborhood Hits	42	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R5A6, Q3U268, Q3U3T0, Q8CA49	Gene names	Tbc1d22a, D15Ertd781e
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 22A.

ARHG1_MOUSE
NC score	0.009775 (rank : 74)	θ value	8.99809 (rank : 81)
Query Neighborhood Hits	95	Target Neighborhood Hits	266	Shared Neighborhood Hits	14
SwissProt Accessions	Q61210, O89074, Q80YE8, Q80YE9, Q91VL3	Gene names	Arhgef1, Lbcl2, Lsc
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (Lymphoid blast crisis-like 2) (Lbc's second cousin).

FOG1_MOUSE
NC score	0.009436 (rank : 75)	θ value	6.88961 (rank : 66)
Query Neighborhood Hits	95	Target Neighborhood Hits	1237	Shared Neighborhood Hits	33
SwissProt Accessions	O35615	Gene names	Zfpm1, Fog, Fog1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

WDHD1_MOUSE
NC score	0.009164 (rank : 76)	θ value	6.88961 (rank : 78)
Query Neighborhood Hits	95	Target Neighborhood Hits	414	Shared Neighborhood Hits	5
SwissProt Accessions	P59328, Q6P408	Gene names	Wdhd1, And1
Domain Architecture	No domain graphic available
Description	WD repeat and HMG-box DNA-binding protein 1 (Acidic nucleoplasmic DNA- binding protein 1) (And-1).

COEA1_MOUSE
NC score	0.008956 (rank : 77)	θ value	8.99809 (rank : 85)
Query Neighborhood Hits	95	Target Neighborhood Hits	402	Shared Neighborhood Hits	14
SwissProt Accessions	Q80X19, Q8C6X3, Q9WV05	Gene names	Col14a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor.

RUFY1_MOUSE
NC score	0.008547 (rank : 78)	θ value	6.88961 (rank : 71)
Query Neighborhood Hits	95	Target Neighborhood Hits	765	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BIJ7, Q8BKQ4, Q8BL21, Q9EPM6	Gene names	Rufy1, Rabip4
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 1 (Rab4-interacting protein).

ZN446_HUMAN
NC score	0.007644 (rank : 79)	θ value	5.27518 (rank : 62)
Query Neighborhood Hits	95	Target Neighborhood Hits	721	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NWS9	Gene names	ZNF446
Domain Architecture	No domain graphic available
Description	Zinc finger protein 446.

SPTN5_HUMAN
NC score	0.007430 (rank : 80)	θ value	8.99809 (rank : 93)
Query Neighborhood Hits	95	Target Neighborhood Hits	674	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NRC6	Gene names	SPTBN5, SPTBN4
Domain Architecture
Description	Spectrin beta chain, brain 4 (Spectrin, non-erythroid beta chain 4) (Beta-V spectrin) (BSPECV).

CABP4_HUMAN
NC score	0.007211 (rank : 81)	θ value	8.99809 (rank : 84)
Query Neighborhood Hits	95	Target Neighborhood Hits	250	Shared Neighborhood Hits	10
SwissProt Accessions	P57796, Q8N4Z2, Q8WWY5	Gene names	CABP4
Domain Architecture
Description	Calcium-binding protein 4 (CaBP4).

ZN687_MOUSE
NC score	0.007193 (rank : 82)	θ value	6.88961 (rank : 80)
Query Neighborhood Hits	95	Target Neighborhood Hits	913	Shared Neighborhood Hits	17
SwissProt Accessions	Q9D2D7, Q6PAP3, Q6ZPQ9	Gene names	Znf687, Kiaa1441, Zfp687
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

BRWD1_MOUSE
NC score	0.007122 (rank : 83)	θ value	6.88961 (rank : 65)
Query Neighborhood Hits	95	Target Neighborhood Hits	478	Shared Neighborhood Hits	9
SwissProt Accessions	Q921C3, Q921C2	Gene names	Brwd1, Wdr9
Domain Architecture	No domain graphic available
Description	Bromodomain and WD repeat domain-containing protein 1 (WD repeat protein 9).

S12A5_MOUSE
NC score	0.007099 (rank : 84)	θ value	6.88961 (rank : 72)
Query Neighborhood Hits	95	Target Neighborhood Hits	59	Shared Neighborhood Hits	3
SwissProt Accessions	Q91V14, Q9Z0M7	Gene names	Slc12a5, Kcc2
Domain Architecture
Description	Solute carrier family 12 member 5 (Electroneutral potassium-chloride cotransporter 2) (K-Cl cotransporter 2) (Neuronal K-Cl cotransporter) (mKCC2).

GLI2_HUMAN
NC score	0.006960 (rank : 85)	θ value	2.36792 (rank : 32)
Query Neighborhood Hits	95	Target Neighborhood Hits	971	Shared Neighborhood Hits	15
SwissProt Accessions	P10070, O60252, O60253, O60254, O60255, Q15590, Q15591	Gene names	GLI2, THP
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI2 (Tax helper protein).

HIP1_HUMAN
NC score	0.006536 (rank : 86)	θ value	8.99809 (rank : 87)
Query Neighborhood Hits	95	Target Neighborhood Hits	1016	Shared Neighborhood Hits	16
SwissProt Accessions	O00291, O00328, Q8TDL4	Gene names	HIP1
Domain Architecture
Description	Huntingtin-interacting protein 1 (HIP-I).

ZFP38_HUMAN
NC score	0.006281 (rank : 87)	θ value	1.06291 (rank : 21)
Query Neighborhood Hits	95	Target Neighborhood Hits	766	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Y5A6, Q9H0B5	Gene names	ZNF38, ZFP38, ZSCAN21
Domain Architecture
Description	Zinc finger protein 38 homolog (Zfp-38) (Zinc finger and SCAN domain- containing protein 21) (NY-REN-21 antigen).

TITIN_HUMAN
NC score	0.006258 (rank : 88)	θ value	1.38821 (rank : 26)
Query Neighborhood Hits	95	Target Neighborhood Hits	2923	Shared Neighborhood Hits	35
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

ZN165_HUMAN
NC score	0.005460 (rank : 89)	θ value	3.0926 (rank : 43)
Query Neighborhood Hits	95	Target Neighborhood Hits	734	Shared Neighborhood Hits	11
SwissProt Accessions	P49910	Gene names	ZNF165, ZPF165, ZSCAN7
Domain Architecture
Description	Zinc finger protein 165 (LD65) (Zinc finger and SCAN domain-containing protein 7).

ZN263_HUMAN
NC score	0.005321 (rank : 90)	θ value	1.38821 (rank : 27)
Query Neighborhood Hits	95	Target Neighborhood Hits	795	Shared Neighborhood Hits	13
SwissProt Accessions	O14978, O43387, Q96H95	Gene names	ZNF263, FPM315
Domain Architecture
Description	Zinc finger protein 263 (Zinc finger protein FPM315).

TAP2_HUMAN
NC score	0.005209 (rank : 91)	θ value	6.88961 (rank : 75)
Query Neighborhood Hits	95	Target Neighborhood Hits	103	Shared Neighborhood Hits	2
SwissProt Accessions	Q03519, Q9UQ83	Gene names	TAP2, ABCB3, PSF2, RING11, Y1
Domain Architecture
Description	Antigen peptide transporter 2 (APT2) (ATP-binding cassette sub-family B member 3) (Peptide transporter TAP2) (Peptide transporter PSF2) (Peptide supply factor 2) (PSF-2) (Peptide transporter involved in antigen processing 2).

ZN193_HUMAN
NC score	0.004974 (rank : 92)	θ value	6.88961 (rank : 79)
Query Neighborhood Hits	95	Target Neighborhood Hits	717	Shared Neighborhood Hits	11
SwissProt Accessions	O15535	Gene names	ZNF193, ZSCAN9
Domain Architecture
Description	Zinc finger protein 193 (PRD51) (Zinc finger and SCAN domain- containing protein 9).

ZN397_HUMAN
NC score	0.004910 (rank : 93)	θ value	2.36792 (rank : 35)
Query Neighborhood Hits	95	Target Neighborhood Hits	749	Shared Neighborhood Hits	11
SwissProt Accessions	Q8NF99, Q9BRM2	Gene names	ZNF397, ZSCAN15
Domain Architecture
Description	Zinc finger protein 397 (Zinc finger and SCAN domain-containing protein 15).

KLHL6_MOUSE
NC score	0.004046 (rank : 94)	θ value	6.88961 (rank : 69)
Query Neighborhood Hits	95	Target Neighborhood Hits	186	Shared Neighborhood Hits	2
SwissProt Accessions	Q6V595	Gene names	Klhl6
Domain Architecture	No domain graphic available
Description	Kelch-like protein 6.

O10Q1_HUMAN
NC score	0.001612 (rank : 95)	θ value	1.06291 (rank : 20)
Query Neighborhood Hits	95	Target Neighborhood Hits	790	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NGQ4	Gene names	OR10Q1
Domain Architecture
Description	Olfactory receptor 10Q1.