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Network neighborhood for query Sequence : PUR4_HUMAN

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PUR4_HUMAN
SwissProt Accessions	O15067	Gene names	PFAS, KIAA0361
Domain Architecture
Description	Phosphoribosylformylglycinamidine synthase (EC 6.3.5.3) (FGAM synthase) (FGAMS) (Formylglycinamide ribotide amidotransferase) (FGARAT) (Formylglycinamide ribotide synthetase).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PUR4_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	23	Target Neighborhood Hits	23	Shared Neighborhood Hits	23
SwissProt Accessions	O15067	Gene names	PFAS, KIAA0361
Domain Architecture
Description	Phosphoribosylformylglycinamidine synthase (EC 6.3.5.3) (FGAM synthase) (FGAMS) (Formylglycinamide ribotide amidotransferase) (FGARAT) (Formylglycinamide ribotide synthetase).

S3TC2_MOUSE
θ value	0.0736092 (rank : 2)	NC score	0.072801 (rank : 2)
Query Neighborhood Hits	23	Target Neighborhood Hits	83	Shared Neighborhood Hits	2
SwissProt Accessions	Q80VA5, Q8BWH2, Q8BXB8, Q8C0G6	Gene names	Sh3tc2, Kiaa1985
Domain Architecture
Description	SH3 domain and tetratricopeptide repeats-containing protein 2.

FUBP2_HUMAN
θ value	0.21417 (rank : 3)	NC score	0.053641 (rank : 4)
Query Neighborhood Hits	23	Target Neighborhood Hits	145	Shared Neighborhood Hits	4
SwissProt Accessions	Q92945, O00301, Q9UNT5, Q9UQH5	Gene names	KHSRP, FUBP2
Domain Architecture
Description	Far upstream element-binding protein 2 (FUSE-binding protein 2) (KH type-splicing regulatory protein) (KSRP) (p75).

CO1A2_MOUSE
θ value	0.365318 (rank : 4)	NC score	0.032357 (rank : 6)
Query Neighborhood Hits	23	Target Neighborhood Hits	388	Shared Neighborhood Hits	5
SwissProt Accessions	Q01149, Q8CGA5	Gene names	Col1a2, Cola2
Domain Architecture
Description	Collagen alpha-2(I) chain precursor.

CO1A2_HUMAN
θ value	0.47712 (rank : 5)	NC score	0.034131 (rank : 5)
Query Neighborhood Hits	23	Target Neighborhood Hits	329	Shared Neighborhood Hits	5
SwissProt Accessions	P08123, P02464, Q9UEB6, Q9UPH0	Gene names	COL1A2
Domain Architecture
Description	Collagen alpha-2(I) chain precursor.

ZN205_HUMAN
θ value	0.47712 (rank : 6)	NC score	0.010135 (rank : 19)
Query Neighborhood Hits	23	Target Neighborhood Hits	743	Shared Neighborhood Hits	6
SwissProt Accessions	O95201	Gene names	ZNF205, ZNF210
Domain Architecture
Description	Zinc finger protein 205 (Zinc finger protein 210).

ZN694_HUMAN
θ value	0.62314 (rank : 7)	NC score	0.011446 (rank : 17)
Query Neighborhood Hits	23	Target Neighborhood Hits	764	Shared Neighborhood Hits	6
SwissProt Accessions	Q63HK3, Q6ZN77	Gene names	ZNF694
Domain Architecture	No domain graphic available
Description	Zinc finger protein 694.

F8I2_HUMAN
θ value	0.813845 (rank : 8)	NC score	0.068374 (rank : 3)
Query Neighborhood Hits	23	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	P23610, Q8IXP3	Gene names	F8A1, F8A
Domain Architecture	No domain graphic available
Description	Factor VIII intron 22 protein (CpG island protein).

ROBO1_MOUSE
θ value	0.813845 (rank : 9)	NC score	0.014532 (rank : 14)
Query Neighborhood Hits	23	Target Neighborhood Hits	559	Shared Neighborhood Hits	2
SwissProt Accessions	O89026	Gene names	Robo1, Dutt1
Domain Architecture
Description	Roundabout homolog 1 precursor.

DMD_HUMAN
θ value	1.38821 (rank : 10)	NC score	0.014139 (rank : 15)
Query Neighborhood Hits	23	Target Neighborhood Hits	1135	Shared Neighborhood Hits	2
SwissProt Accessions	P11532, Q02295, Q14169, Q14170, Q5JYU0, Q7KZ48	Gene names	DMD
Domain Architecture
Description	Dystrophin.

ZN219_HUMAN
θ value	1.38821 (rank : 11)	NC score	0.015000 (rank : 13)
Query Neighborhood Hits	23	Target Neighborhood Hits	876	Shared Neighborhood Hits	6
SwissProt Accessions	Q9P2Y4, Q8IYC1, Q9BW28	Gene names	ZNF219
Domain Architecture	No domain graphic available
Description	Zinc finger protein 219.

PELP1_HUMAN
θ value	2.36792 (rank : 12)	NC score	0.029808 (rank : 7)
Query Neighborhood Hits	23	Target Neighborhood Hits	596	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

ZN690_HUMAN
θ value	2.36792 (rank : 13)	NC score	0.009726 (rank : 20)
Query Neighborhood Hits	23	Target Neighborhood Hits	777	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IWY8, Q32M75, Q32M76, Q8NA40	Gene names	ZNF690
Domain Architecture	No domain graphic available
Description	Zinc finger protein 690.

ESPL1_HUMAN
θ value	4.03905 (rank : 14)	NC score	0.028284 (rank : 8)
Query Neighborhood Hits	23	Target Neighborhood Hits	95	Shared Neighborhood Hits	3
SwissProt Accessions	Q14674	Gene names	ESPL1, ESP1, KIAA0165
Domain Architecture
Description	Separin (EC 3.4.22.49) (Separase) (Caspase-like protein ESPL1) (Extra spindle poles-like 1 protein).

ZN202_HUMAN
θ value	4.03905 (rank : 15)	NC score	0.007837 (rank : 21)
Query Neighborhood Hits	23	Target Neighborhood Hits	756	Shared Neighborhood Hits	6
SwissProt Accessions	O95125, Q4JG21, Q9H1B9, Q9NSM4	Gene names	ZNF202
Domain Architecture
Description	Zinc finger protein 202.

CB017_HUMAN
θ value	6.88961 (rank : 16)	NC score	0.025530 (rank : 9)
Query Neighborhood Hits	23	Target Neighborhood Hits	38	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NC44, Q6P1P5, Q9H0K7	Gene names	C2orf17
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C2orf17.

GFRA3_HUMAN
θ value	6.88961 (rank : 17)	NC score	0.018119 (rank : 12)
Query Neighborhood Hits	23	Target Neighborhood Hits	27	Shared Neighborhood Hits	2
SwissProt Accessions	O60609, Q6UW20, Q8IUZ2	Gene names	GFRA3
Domain Architecture
Description	GDNF family receptor alpha-3 precursor (GFR-alpha-3).

CO8A2_MOUSE
θ value	8.99809 (rank : 18)	NC score	0.012762 (rank : 16)
Query Neighborhood Hits	23	Target Neighborhood Hits	273	Shared Neighborhood Hits	4
SwissProt Accessions	P25318, Q68ED0, Q6KAQ4, Q6P1C4	Gene names	Col8a2
Domain Architecture	No domain graphic available
Description	Collagen alpha-2(VIII) chain precursor (Endothelial collagen).

IF4G1_MOUSE
θ value	8.99809 (rank : 19)	NC score	0.011316 (rank : 18)
Query Neighborhood Hits	23	Target Neighborhood Hits	534	Shared Neighborhood Hits	4
SwissProt Accessions	Q6NZJ6, Q6NZN8, Q8BW99	Gene names	Eif4g1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1).

NRK_MOUSE
θ value	8.99809 (rank : 20)	NC score	0.002250 (rank : 23)
Query Neighborhood Hits	23	Target Neighborhood Hits	899	Shared Neighborhood Hits	2
SwissProt Accessions	Q9R0G8, Q6NV55, Q8C9S9, Q9R0S4	Gene names	Nrk, Nesk
Domain Architecture	No domain graphic available
Description	Nik-related protein kinase (EC 2.7.11.1) (Nck-interacting kinase-like embryo specific kinase) (NIK-like embryo-specific kinase) (NESK).

PCD15_HUMAN
θ value	8.99809 (rank : 21)	NC score	0.004893 (rank : 22)
Query Neighborhood Hits	23	Target Neighborhood Hits	289	Shared Neighborhood Hits	3
SwissProt Accessions	Q96QU1, Q96QT8	Gene names	PCDH15
Domain Architecture
Description	Protocadherin-15 precursor.

TISB_HUMAN
θ value	8.99809 (rank : 22)	NC score	0.022134 (rank : 11)
Query Neighborhood Hits	23	Target Neighborhood Hits	56	Shared Neighborhood Hits	3
SwissProt Accessions	Q07352, Q13851	Gene names	ZFP36L1, BERG36, BRF1, ERF1, TIS11B
Domain Architecture
Description	Butyrate response factor 1 (TIS11B protein) (EGF-response factor 1) (ERF-1).

TISB_MOUSE
θ value	8.99809 (rank : 23)	NC score	0.022184 (rank : 10)
Query Neighborhood Hits	23	Target Neighborhood Hits	56	Shared Neighborhood Hits	3
SwissProt Accessions	P23950	Gene names	Zfp36l1, Brf1, Tis11b
Domain Architecture
Description	Butyrate response factor 1 (TIS11B protein).

Hits sorted by NC score

PUR4_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	23	Target Neighborhood Hits	23	Shared Neighborhood Hits	23
SwissProt Accessions	O15067	Gene names	PFAS, KIAA0361
Domain Architecture
Description	Phosphoribosylformylglycinamidine synthase (EC 6.3.5.3) (FGAM synthase) (FGAMS) (Formylglycinamide ribotide amidotransferase) (FGARAT) (Formylglycinamide ribotide synthetase).

S3TC2_MOUSE
NC score	0.072801 (rank : 2)	θ value	0.0736092 (rank : 2)
Query Neighborhood Hits	23	Target Neighborhood Hits	83	Shared Neighborhood Hits	2
SwissProt Accessions	Q80VA5, Q8BWH2, Q8BXB8, Q8C0G6	Gene names	Sh3tc2, Kiaa1985
Domain Architecture
Description	SH3 domain and tetratricopeptide repeats-containing protein 2.

F8I2_HUMAN
NC score	0.068374 (rank : 3)	θ value	0.813845 (rank : 8)
Query Neighborhood Hits	23	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	P23610, Q8IXP3	Gene names	F8A1, F8A
Domain Architecture	No domain graphic available
Description	Factor VIII intron 22 protein (CpG island protein).

FUBP2_HUMAN
NC score	0.053641 (rank : 4)	θ value	0.21417 (rank : 3)
Query Neighborhood Hits	23	Target Neighborhood Hits	145	Shared Neighborhood Hits	4
SwissProt Accessions	Q92945, O00301, Q9UNT5, Q9UQH5	Gene names	KHSRP, FUBP2
Domain Architecture
Description	Far upstream element-binding protein 2 (FUSE-binding protein 2) (KH type-splicing regulatory protein) (KSRP) (p75).

CO1A2_HUMAN
NC score	0.034131 (rank : 5)	θ value	0.47712 (rank : 5)
Query Neighborhood Hits	23	Target Neighborhood Hits	329	Shared Neighborhood Hits	5
SwissProt Accessions	P08123, P02464, Q9UEB6, Q9UPH0	Gene names	COL1A2
Domain Architecture
Description	Collagen alpha-2(I) chain precursor.

CO1A2_MOUSE
NC score	0.032357 (rank : 6)	θ value	0.365318 (rank : 4)
Query Neighborhood Hits	23	Target Neighborhood Hits	388	Shared Neighborhood Hits	5
SwissProt Accessions	Q01149, Q8CGA5	Gene names	Col1a2, Cola2
Domain Architecture
Description	Collagen alpha-2(I) chain precursor.

PELP1_HUMAN
NC score	0.029808 (rank : 7)	θ value	2.36792 (rank : 12)
Query Neighborhood Hits	23	Target Neighborhood Hits	596	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

ESPL1_HUMAN
NC score	0.028284 (rank : 8)	θ value	4.03905 (rank : 14)
Query Neighborhood Hits	23	Target Neighborhood Hits	95	Shared Neighborhood Hits	3
SwissProt Accessions	Q14674	Gene names	ESPL1, ESP1, KIAA0165
Domain Architecture
Description	Separin (EC 3.4.22.49) (Separase) (Caspase-like protein ESPL1) (Extra spindle poles-like 1 protein).

CB017_HUMAN
NC score	0.025530 (rank : 9)	θ value	6.88961 (rank : 16)
Query Neighborhood Hits	23	Target Neighborhood Hits	38	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NC44, Q6P1P5, Q9H0K7	Gene names	C2orf17
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C2orf17.

TISB_MOUSE
NC score	0.022184 (rank : 10)	θ value	8.99809 (rank : 23)
Query Neighborhood Hits	23	Target Neighborhood Hits	56	Shared Neighborhood Hits	3
SwissProt Accessions	P23950	Gene names	Zfp36l1, Brf1, Tis11b
Domain Architecture
Description	Butyrate response factor 1 (TIS11B protein).

TISB_HUMAN
NC score	0.022134 (rank : 11)	θ value	8.99809 (rank : 22)
Query Neighborhood Hits	23	Target Neighborhood Hits	56	Shared Neighborhood Hits	3
SwissProt Accessions	Q07352, Q13851	Gene names	ZFP36L1, BERG36, BRF1, ERF1, TIS11B
Domain Architecture
Description	Butyrate response factor 1 (TIS11B protein) (EGF-response factor 1) (ERF-1).

GFRA3_HUMAN
NC score	0.018119 (rank : 12)	θ value	6.88961 (rank : 17)
Query Neighborhood Hits	23	Target Neighborhood Hits	27	Shared Neighborhood Hits	2
SwissProt Accessions	O60609, Q6UW20, Q8IUZ2	Gene names	GFRA3
Domain Architecture
Description	GDNF family receptor alpha-3 precursor (GFR-alpha-3).

ZN219_HUMAN
NC score	0.015000 (rank : 13)	θ value	1.38821 (rank : 11)
Query Neighborhood Hits	23	Target Neighborhood Hits	876	Shared Neighborhood Hits	6
SwissProt Accessions	Q9P2Y4, Q8IYC1, Q9BW28	Gene names	ZNF219
Domain Architecture	No domain graphic available
Description	Zinc finger protein 219.

ROBO1_MOUSE
NC score	0.014532 (rank : 14)	θ value	0.813845 (rank : 9)
Query Neighborhood Hits	23	Target Neighborhood Hits	559	Shared Neighborhood Hits	2
SwissProt Accessions	O89026	Gene names	Robo1, Dutt1
Domain Architecture
Description	Roundabout homolog 1 precursor.

DMD_HUMAN
NC score	0.014139 (rank : 15)	θ value	1.38821 (rank : 10)
Query Neighborhood Hits	23	Target Neighborhood Hits	1135	Shared Neighborhood Hits	2
SwissProt Accessions	P11532, Q02295, Q14169, Q14170, Q5JYU0, Q7KZ48	Gene names	DMD
Domain Architecture
Description	Dystrophin.

CO8A2_MOUSE
NC score	0.012762 (rank : 16)	θ value	8.99809 (rank : 18)
Query Neighborhood Hits	23	Target Neighborhood Hits	273	Shared Neighborhood Hits	4
SwissProt Accessions	P25318, Q68ED0, Q6KAQ4, Q6P1C4	Gene names	Col8a2
Domain Architecture	No domain graphic available
Description	Collagen alpha-2(VIII) chain precursor (Endothelial collagen).

ZN694_HUMAN
NC score	0.011446 (rank : 17)	θ value	0.62314 (rank : 7)
Query Neighborhood Hits	23	Target Neighborhood Hits	764	Shared Neighborhood Hits	6
SwissProt Accessions	Q63HK3, Q6ZN77	Gene names	ZNF694
Domain Architecture	No domain graphic available
Description	Zinc finger protein 694.

IF4G1_MOUSE
NC score	0.011316 (rank : 18)	θ value	8.99809 (rank : 19)
Query Neighborhood Hits	23	Target Neighborhood Hits	534	Shared Neighborhood Hits	4
SwissProt Accessions	Q6NZJ6, Q6NZN8, Q8BW99	Gene names	Eif4g1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1).

ZN205_HUMAN
NC score	0.010135 (rank : 19)	θ value	0.47712 (rank : 6)
Query Neighborhood Hits	23	Target Neighborhood Hits	743	Shared Neighborhood Hits	6
SwissProt Accessions	O95201	Gene names	ZNF205, ZNF210
Domain Architecture
Description	Zinc finger protein 205 (Zinc finger protein 210).

ZN690_HUMAN
NC score	0.009726 (rank : 20)	θ value	2.36792 (rank : 13)
Query Neighborhood Hits	23	Target Neighborhood Hits	777	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IWY8, Q32M75, Q32M76, Q8NA40	Gene names	ZNF690
Domain Architecture	No domain graphic available
Description	Zinc finger protein 690.

ZN202_HUMAN
NC score	0.007837 (rank : 21)	θ value	4.03905 (rank : 15)
Query Neighborhood Hits	23	Target Neighborhood Hits	756	Shared Neighborhood Hits	6
SwissProt Accessions	O95125, Q4JG21, Q9H1B9, Q9NSM4	Gene names	ZNF202
Domain Architecture
Description	Zinc finger protein 202.

PCD15_HUMAN
NC score	0.004893 (rank : 22)	θ value	8.99809 (rank : 21)
Query Neighborhood Hits	23	Target Neighborhood Hits	289	Shared Neighborhood Hits	3
SwissProt Accessions	Q96QU1, Q96QT8	Gene names	PCDH15
Domain Architecture
Description	Protocadherin-15 precursor.

NRK_MOUSE
NC score	0.002250 (rank : 23)	θ value	8.99809 (rank : 20)
Query Neighborhood Hits	23	Target Neighborhood Hits	899	Shared Neighborhood Hits	2
SwissProt Accessions	Q9R0G8, Q6NV55, Q8C9S9, Q9R0S4	Gene names	Nrk, Nesk
Domain Architecture	No domain graphic available
Description	Nik-related protein kinase (EC 2.7.11.1) (Nck-interacting kinase-like embryo specific kinase) (NIK-like embryo-specific kinase) (NESK).