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Network neighborhood for query Sequence : F8I2_HUMAN

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F8I2_HUMAN
SwissProt Accessions	P23610, Q8IXP3	Gene names	F8A1, F8A
Domain Architecture	No domain graphic available
Description	Factor VIII intron 22 protein (CpG island protein).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

F8I2_HUMAN
θ value	4.03687e-117 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	17	Target Neighborhood Hits	17	Shared Neighborhood Hits	17
SwissProt Accessions	P23610, Q8IXP3	Gene names	F8A1, F8A
Domain Architecture	No domain graphic available
Description	Factor VIII intron 22 protein (CpG island protein).

F8I2_MOUSE
θ value	6.88586e-117 (rank : 2)	NC score	0.985314 (rank : 2)
Query Neighborhood Hits	17	Target Neighborhood Hits	18	Shared Neighborhood Hits	3
SwissProt Accessions	Q00558	Gene names	F8a1, F8a
Domain Architecture	No domain graphic available
Description	Factor VIII intron 22 protein (CpG island protein).

GPS2_HUMAN
θ value	0.62314 (rank : 3)	NC score	0.055003 (rank : 4)
Query Neighborhood Hits	17	Target Neighborhood Hits	459	Shared Neighborhood Hits	4
SwissProt Accessions	Q13227	Gene names	GPS2
Domain Architecture	No domain graphic available
Description	G protein pathway suppressor 2 (Protein GPS2).

CAC1G_HUMAN
θ value	0.813845 (rank : 4)	NC score	0.022452 (rank : 9)
Query Neighborhood Hits	17	Target Neighborhood Hits	587	Shared Neighborhood Hits	5
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

GRB10_HUMAN
θ value	0.813845 (rank : 5)	NC score	0.029698 (rank : 7)
Query Neighborhood Hits	17	Target Neighborhood Hits	147	Shared Neighborhood Hits	2
SwissProt Accessions	Q13322, O00427, O00701, O75222, Q92606, Q92907, Q92948	Gene names	GRB10, GRBIR, KIAA0207
Domain Architecture
Description	Growth factor receptor-bound protein 10 (GRB10 adaptor protein) (Insulin receptor-binding protein GRB-IR).

PUR4_HUMAN
θ value	0.813845 (rank : 6)	NC score	0.068374 (rank : 3)
Query Neighborhood Hits	17	Target Neighborhood Hits	23	Shared Neighborhood Hits	2
SwissProt Accessions	O15067	Gene names	PFAS, KIAA0361
Domain Architecture
Description	Phosphoribosylformylglycinamidine synthase (EC 6.3.5.3) (FGAM synthase) (FGAMS) (Formylglycinamide ribotide amidotransferase) (FGARAT) (Formylglycinamide ribotide synthetase).

PAR6G_HUMAN
θ value	1.38821 (rank : 7)	NC score	0.028042 (rank : 8)
Query Neighborhood Hits	17	Target Neighborhood Hits	159	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BYG4	Gene names	PARD6G, PAR6G
Domain Architecture
Description	Partitioning defective 6 homolog gamma (PAR-6 gamma) (PAR6D).

ULK1_MOUSE
θ value	2.36792 (rank : 8)	NC score	0.008909 (rank : 16)
Query Neighborhood Hits	17	Target Neighborhood Hits	1214	Shared Neighborhood Hits	6
SwissProt Accessions	O70405, Q6PGB2	Gene names	Ulk1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1) (Serine/threonine-protein kinase Unc51.1).

OGFR_HUMAN
θ value	4.03905 (rank : 9)	NC score	0.011409 (rank : 14)
Query Neighborhood Hits	17	Target Neighborhood Hits	1582	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

MAP1A_HUMAN
θ value	5.27518 (rank : 10)	NC score	0.013579 (rank : 12)
Query Neighborhood Hits	17	Target Neighborhood Hits	1626	Shared Neighborhood Hits	7
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

RRAS_HUMAN
θ value	5.27518 (rank : 11)	NC score	0.005195 (rank : 17)
Query Neighborhood Hits	17	Target Neighborhood Hits	262	Shared Neighborhood Hits	2
SwissProt Accessions	P10301	Gene names	RRAS
Domain Architecture
Description	Ras-related protein R-Ras (p23).

SNAG_HUMAN
θ value	6.88961 (rank : 12)	NC score	0.034307 (rank : 5)
Query Neighborhood Hits	17	Target Neighborhood Hits	30	Shared Neighborhood Hits	3
SwissProt Accessions	Q99747, Q9BUV1	Gene names	NAPG, SNAPG
Domain Architecture	No domain graphic available
Description	Gamma-soluble NSF attachment protein (SNAP-gamma) (N-ethylmaleimide- sensitive factor attachment protein, gamma).

SNAG_MOUSE
θ value	6.88961 (rank : 13)	NC score	0.033818 (rank : 6)
Query Neighborhood Hits	17	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CWZ7, Q3TPT4	Gene names	Napg, Snapg
Domain Architecture	No domain graphic available
Description	Gamma-soluble NSF attachment protein (SNAP-gamma) (N-ethylmaleimide- sensitive factor attachment protein, gamma).

EP400_MOUSE
θ value	8.99809 (rank : 14)	NC score	0.009973 (rank : 15)
Query Neighborhood Hits	17	Target Neighborhood Hits	592	Shared Neighborhood Hits	6
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

GSCR1_HUMAN
θ value	8.99809 (rank : 15)	NC score	0.017896 (rank : 10)
Query Neighborhood Hits	17	Target Neighborhood Hits	674	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

PTC2_HUMAN
θ value	8.99809 (rank : 16)	NC score	0.012497 (rank : 13)
Query Neighborhood Hits	17	Target Neighborhood Hits	63	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y6C5, O95341, O95856, Q5QP87, Q6UX14	Gene names	PTCH2
Domain Architecture
Description	Protein patched homolog 2 (PTC2).

TM55B_MOUSE
θ value	8.99809 (rank : 17)	NC score	0.015352 (rank : 11)
Query Neighborhood Hits	17	Target Neighborhood Hits	50	Shared Neighborhood Hits	2
SwissProt Accessions	Q3TWL2	Gene names	Tmem55b
Domain Architecture	No domain graphic available
Description	Transmembrane protein 55B (EC 3.1.3.-) (Type I phosphatidylinositol 4,5-bisphosphate 4-phosphatase) (PtdIns-4,5-P2 4-Ptase I).

Hits sorted by NC score

F8I2_HUMAN
NC score	0.999962 (rank : 1)	θ value	4.03687e-117 (rank : 1)
Query Neighborhood Hits	17	Target Neighborhood Hits	17	Shared Neighborhood Hits	17
SwissProt Accessions	P23610, Q8IXP3	Gene names	F8A1, F8A
Domain Architecture	No domain graphic available
Description	Factor VIII intron 22 protein (CpG island protein).

F8I2_MOUSE
NC score	0.985314 (rank : 2)	θ value	6.88586e-117 (rank : 2)
Query Neighborhood Hits	17	Target Neighborhood Hits	18	Shared Neighborhood Hits	3
SwissProt Accessions	Q00558	Gene names	F8a1, F8a
Domain Architecture	No domain graphic available
Description	Factor VIII intron 22 protein (CpG island protein).

PUR4_HUMAN
NC score	0.068374 (rank : 3)	θ value	0.813845 (rank : 6)
Query Neighborhood Hits	17	Target Neighborhood Hits	23	Shared Neighborhood Hits	2
SwissProt Accessions	O15067	Gene names	PFAS, KIAA0361
Domain Architecture
Description	Phosphoribosylformylglycinamidine synthase (EC 6.3.5.3) (FGAM synthase) (FGAMS) (Formylglycinamide ribotide amidotransferase) (FGARAT) (Formylglycinamide ribotide synthetase).

GPS2_HUMAN
NC score	0.055003 (rank : 4)	θ value	0.62314 (rank : 3)
Query Neighborhood Hits	17	Target Neighborhood Hits	459	Shared Neighborhood Hits	4
SwissProt Accessions	Q13227	Gene names	GPS2
Domain Architecture	No domain graphic available
Description	G protein pathway suppressor 2 (Protein GPS2).

SNAG_HUMAN
NC score	0.034307 (rank : 5)	θ value	6.88961 (rank : 12)
Query Neighborhood Hits	17	Target Neighborhood Hits	30	Shared Neighborhood Hits	3
SwissProt Accessions	Q99747, Q9BUV1	Gene names	NAPG, SNAPG
Domain Architecture	No domain graphic available
Description	Gamma-soluble NSF attachment protein (SNAP-gamma) (N-ethylmaleimide- sensitive factor attachment protein, gamma).

SNAG_MOUSE
NC score	0.033818 (rank : 6)	θ value	6.88961 (rank : 13)
Query Neighborhood Hits	17	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CWZ7, Q3TPT4	Gene names	Napg, Snapg
Domain Architecture	No domain graphic available
Description	Gamma-soluble NSF attachment protein (SNAP-gamma) (N-ethylmaleimide- sensitive factor attachment protein, gamma).

GRB10_HUMAN
NC score	0.029698 (rank : 7)	θ value	0.813845 (rank : 5)
Query Neighborhood Hits	17	Target Neighborhood Hits	147	Shared Neighborhood Hits	2
SwissProt Accessions	Q13322, O00427, O00701, O75222, Q92606, Q92907, Q92948	Gene names	GRB10, GRBIR, KIAA0207
Domain Architecture
Description	Growth factor receptor-bound protein 10 (GRB10 adaptor protein) (Insulin receptor-binding protein GRB-IR).

PAR6G_HUMAN
NC score	0.028042 (rank : 8)	θ value	1.38821 (rank : 7)
Query Neighborhood Hits	17	Target Neighborhood Hits	159	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BYG4	Gene names	PARD6G, PAR6G
Domain Architecture
Description	Partitioning defective 6 homolog gamma (PAR-6 gamma) (PAR6D).

CAC1G_HUMAN
NC score	0.022452 (rank : 9)	θ value	0.813845 (rank : 4)
Query Neighborhood Hits	17	Target Neighborhood Hits	587	Shared Neighborhood Hits	5
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

GSCR1_HUMAN
NC score	0.017896 (rank : 10)	θ value	8.99809 (rank : 15)
Query Neighborhood Hits	17	Target Neighborhood Hits	674	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

TM55B_MOUSE
NC score	0.015352 (rank : 11)	θ value	8.99809 (rank : 17)
Query Neighborhood Hits	17	Target Neighborhood Hits	50	Shared Neighborhood Hits	2
SwissProt Accessions	Q3TWL2	Gene names	Tmem55b
Domain Architecture	No domain graphic available
Description	Transmembrane protein 55B (EC 3.1.3.-) (Type I phosphatidylinositol 4,5-bisphosphate 4-phosphatase) (PtdIns-4,5-P2 4-Ptase I).

MAP1A_HUMAN
NC score	0.013579 (rank : 12)	θ value	5.27518 (rank : 10)
Query Neighborhood Hits	17	Target Neighborhood Hits	1626	Shared Neighborhood Hits	7
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

PTC2_HUMAN
NC score	0.012497 (rank : 13)	θ value	8.99809 (rank : 16)
Query Neighborhood Hits	17	Target Neighborhood Hits	63	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y6C5, O95341, O95856, Q5QP87, Q6UX14	Gene names	PTCH2
Domain Architecture
Description	Protein patched homolog 2 (PTC2).

OGFR_HUMAN
NC score	0.011409 (rank : 14)	θ value	4.03905 (rank : 9)
Query Neighborhood Hits	17	Target Neighborhood Hits	1582	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

EP400_MOUSE
NC score	0.009973 (rank : 15)	θ value	8.99809 (rank : 14)
Query Neighborhood Hits	17	Target Neighborhood Hits	592	Shared Neighborhood Hits	6
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

ULK1_MOUSE
NC score	0.008909 (rank : 16)	θ value	2.36792 (rank : 8)
Query Neighborhood Hits	17	Target Neighborhood Hits	1214	Shared Neighborhood Hits	6
SwissProt Accessions	O70405, Q6PGB2	Gene names	Ulk1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1) (Serine/threonine-protein kinase Unc51.1).

RRAS_HUMAN
NC score	0.005195 (rank : 17)	θ value	5.27518 (rank : 11)
Query Neighborhood Hits	17	Target Neighborhood Hits	262	Shared Neighborhood Hits	2
SwissProt Accessions	P10301	Gene names	RRAS
Domain Architecture
Description	Ras-related protein R-Ras (p23).