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Network neighborhood for query Sequence : CUL4A_HUMAN

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CUL4A_HUMAN
SwissProt Accessions	Q13619, O75834, Q589T6, Q5TC62, Q6UP08, Q9UP17	Gene names	CUL4A
Domain Architecture
Description	Cullin-4A (CUL-4A).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CUL4A_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	40	Target Neighborhood Hits	40	Shared Neighborhood Hits	40
SwissProt Accessions	Q13619, O75834, Q589T6, Q5TC62, Q6UP08, Q9UP17	Gene names	CUL4A
Domain Architecture
Description	Cullin-4A (CUL-4A).

CUL4A_MOUSE
θ value	0 (rank : 2)	NC score	0.998809 (rank : 2)
Query Neighborhood Hits	40	Target Neighborhood Hits	31	Shared Neighborhood Hits	27
SwissProt Accessions	Q3TCH7, Q3THM3, Q91Z44	Gene names	Cul4a
Domain Architecture	No domain graphic available
Description	Cullin-4A (CUL-4A).

CUL4B_HUMAN
θ value	0 (rank : 3)	NC score	0.993281 (rank : 3)
Query Neighborhood Hits	40	Target Neighborhood Hits	80	Shared Neighborhood Hits	21
SwissProt Accessions	Q13620, Q6PIE4, Q6UP07, Q7Z673, Q9BY37, Q9UEB7, Q9UED7	Gene names	CUL4B, KIAA0695
Domain Architecture
Description	Cullin-4B (CUL-4B).

CUL3_MOUSE
θ value	1.20704e-137 (rank : 4)	NC score	0.958779 (rank : 4)
Query Neighborhood Hits	40	Target Neighborhood Hits	39	Shared Neighborhood Hits	14
SwissProt Accessions	Q9JLV5	Gene names	Cul3
Domain Architecture
Description	Cullin-3 (CUL-3).

CUL3_HUMAN
θ value	3.51195e-137 (rank : 5)	NC score	0.958609 (rank : 5)
Query Neighborhood Hits	40	Target Neighborhood Hits	42	Shared Neighborhood Hits	14
SwissProt Accessions	Q13618, O75415, Q569L3, Q9UBI8, Q9UET7	Gene names	CUL3, KIAA0617
Domain Architecture
Description	Cullin-3 (CUL-3).

CUL1_HUMAN
θ value	1.2666e-86 (rank : 6)	NC score	0.925376 (rank : 6)
Query Neighborhood Hits	40	Target Neighborhood Hits	38	Shared Neighborhood Hits	14
SwissProt Accessions	Q13616, O60719, Q8IYW1	Gene names	CUL1
Domain Architecture
Description	Cullin-1 (CUL-1).

CUL1_MOUSE
θ value	1.2666e-86 (rank : 7)	NC score	0.925367 (rank : 7)
Query Neighborhood Hits	40	Target Neighborhood Hits	38	Shared Neighborhood Hits	14
SwissProt Accessions	Q9WTX6, Q9WUI7	Gene names	Cul1
Domain Architecture
Description	Cullin-1 (CUL-1).

CUL2_HUMAN
θ value	5.33382e-77 (rank : 8)	NC score	0.920137 (rank : 8)
Query Neighborhood Hits	40	Target Neighborhood Hits	36	Shared Neighborhood Hits	13
SwissProt Accessions	Q13617, O00200, Q9UNF9	Gene names	CUL2
Domain Architecture
Description	Cullin-2 (CUL-2).

CUL2_MOUSE
θ value	2.92676e-75 (rank : 9)	NC score	0.919440 (rank : 9)
Query Neighborhood Hits	40	Target Neighborhood Hits	29	Shared Neighborhood Hits	13
SwissProt Accessions	Q9D4H8, Q3TUR8	Gene names	Cul2
Domain Architecture
Description	Cullin-2 (CUL-2).

CUL5_MOUSE
θ value	2.10721e-57 (rank : 10)	NC score	0.890014 (rank : 10)
Query Neighborhood Hits	40	Target Neighborhood Hits	41	Shared Neighborhood Hits	13
SwissProt Accessions	Q9D5V5, Q8BMQ6, Q8BV53, Q8C098	Gene names	Cul5
Domain Architecture
Description	Cullin-5 (CUL-5).

CUL5_HUMAN
θ value	8.00737e-57 (rank : 11)	NC score	0.889418 (rank : 11)
Query Neighborhood Hits	40	Target Neighborhood Hits	46	Shared Neighborhood Hits	13
SwissProt Accessions	Q93034, O14766, Q9BZC6	Gene names	CUL5, VACM1
Domain Architecture
Description	Cullin-5 (CUL-5) (Vasopressin-activated calcium-mobilizing receptor) (VACM-1).

ANC2_HUMAN
θ value	1.47974e-10 (rank : 12)	NC score	0.455190 (rank : 13)
Query Neighborhood Hits	40	Target Neighborhood Hits	29	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UJX6, Q5VSG1, Q96DG5, Q96GG4, Q9P2E1	Gene names	ANAPC2, APC2, KIAA1406
Domain Architecture
Description	Anaphase-promoting complex subunit 2 (APC2) (Cyclosome subunit 2).

ANC2_MOUSE
θ value	1.9326e-10 (rank : 13)	NC score	0.457123 (rank : 12)
Query Neighborhood Hits	40	Target Neighborhood Hits	25	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BZQ7, Q8R2Q1	Gene names	Anapc2
Domain Architecture
Description	Anaphase-promoting complex subunit 2 (APC2) (Cyclosome subunit 2).

PARC_MOUSE
θ value	0.00020696 (rank : 14)	NC score	0.097661 (rank : 15)
Query Neighborhood Hits	40	Target Neighborhood Hits	114	Shared Neighborhood Hits	5
SwissProt Accessions	Q80TT8, Q8BKL9, Q8CGC0, Q8R363	Gene names	Parc, Kiaa0708
Domain Architecture
Description	p53-associated parkin-like cytoplasmic protein.

PARC_HUMAN
θ value	0.00175202 (rank : 15)	NC score	0.118721 (rank : 14)
Query Neighborhood Hits	40	Target Neighborhood Hits	148	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IWT3, O75188, Q68CP2, Q68D92, Q8N3W9, Q9BU56	Gene names	PARC, H7AP1, KIAA0708
Domain Architecture
Description	p53-associated parkin-like cytoplasmic protein (UbcH7-associated protein 1).

CP135_HUMAN
θ value	0.00869519 (rank : 16)	NC score	0.020496 (rank : 23)
Query Neighborhood Hits	40	Target Neighborhood Hits	1290	Shared Neighborhood Hits	15
SwissProt Accessions	Q66GS9, O75130, Q9H8H7	Gene names	CEP135, CEP4, KIAA0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

LAMA2_HUMAN
θ value	0.0330416 (rank : 17)	NC score	0.027305 (rank : 19)
Query Neighborhood Hits	40	Target Neighborhood Hits	1092	Shared Neighborhood Hits	12
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

LAMA2_MOUSE
θ value	0.279714 (rank : 18)	NC score	0.021256 (rank : 22)
Query Neighborhood Hits	40	Target Neighborhood Hits	1198	Shared Neighborhood Hits	15
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

MYH11_HUMAN
θ value	0.47712 (rank : 19)	NC score	0.016845 (rank : 29)
Query Neighborhood Hits	40	Target Neighborhood Hits	1806	Shared Neighborhood Hits	15
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

MYH11_MOUSE
θ value	0.62314 (rank : 20)	NC score	0.017425 (rank : 28)
Query Neighborhood Hits	40	Target Neighborhood Hits	1777	Shared Neighborhood Hits	16
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

REST_HUMAN
θ value	1.38821 (rank : 21)	NC score	0.009525 (rank : 37)
Query Neighborhood Hits	40	Target Neighborhood Hits	1605	Shared Neighborhood Hits	15
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

SPTN5_HUMAN
θ value	1.38821 (rank : 22)	NC score	0.014030 (rank : 35)
Query Neighborhood Hits	40	Target Neighborhood Hits	674	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NRC6	Gene names	SPTBN5, SPTBN4
Domain Architecture
Description	Spectrin beta chain, brain 4 (Spectrin, non-erythroid beta chain 4) (Beta-V spectrin) (BSPECV).

MYH14_MOUSE
θ value	2.36792 (rank : 23)	NC score	0.016276 (rank : 30)
Query Neighborhood Hits	40	Target Neighborhood Hits	1225	Shared Neighborhood Hits	16
SwissProt Accessions	Q6URW6, Q80V64, Q80ZE6	Gene names	Myh14
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

SACS_HUMAN
θ value	2.36792 (rank : 24)	NC score	0.022478 (rank : 21)
Query Neighborhood Hits	40	Target Neighborhood Hits	128	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NZJ4, O94835	Gene names	SACS, KIAA0730
Domain Architecture
Description	Sacsin.

SACS_MOUSE
θ value	2.36792 (rank : 25)	NC score	0.025249 (rank : 20)
Query Neighborhood Hits	40	Target Neighborhood Hits	99	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JLC8	Gene names	Sacs
Domain Architecture
Description	Sacsin.

TLR3_MOUSE
θ value	2.36792 (rank : 26)	NC score	0.006934 (rank : 39)
Query Neighborhood Hits	40	Target Neighborhood Hits	298	Shared Neighborhood Hits	3
SwissProt Accessions	Q99MB1, Q91ZM4	Gene names	Tlr3
Domain Architecture
Description	Toll-like receptor 3 precursor (CD283 antigen).

TLR3_HUMAN
θ value	3.0926 (rank : 27)	NC score	0.006407 (rank : 40)
Query Neighborhood Hits	40	Target Neighborhood Hits	323	Shared Neighborhood Hits	3
SwissProt Accessions	O15455	Gene names	TLR3
Domain Architecture
Description	Toll-like receptor 3 precursor (CD283 antigen).

DYH5_HUMAN
θ value	4.03905 (rank : 28)	NC score	0.017618 (rank : 27)
Query Neighborhood Hits	40	Target Neighborhood Hits	323	Shared Neighborhood Hits	9
SwissProt Accessions	Q8TE73, Q92860, Q96L74, Q9H5S7, Q9HCG9	Gene names	DNAH5, DNAHC5, KIAA1603
Domain Architecture	No domain graphic available
Description	Ciliary dynein heavy chain 5 (Axonemal beta dynein heavy chain 5) (HL1).

K2C6B_HUMAN
θ value	4.03905 (rank : 29)	NC score	0.005874 (rank : 41)
Query Neighborhood Hits	40	Target Neighborhood Hits	526	Shared Neighborhood Hits	10
SwissProt Accessions	P04259, P48669	Gene names	KRT6B, K6B
Domain Architecture
Description	Keratin, type II cytoskeletal 6B (Cytokeratin-6B) (CK 6B) (K6b keratin).

K2C6E_HUMAN
θ value	4.03905 (rank : 30)	NC score	0.005783 (rank : 42)
Query Neighborhood Hits	40	Target Neighborhood Hits	516	Shared Neighborhood Hits	10
SwissProt Accessions	P48668, Q7RTN9	Gene names	KRT6E
Domain Architecture
Description	Keratin, type II cytoskeletal 6E (Cytokeratin-6E) (CK 6E) (K6e keratin) (Keratin K6h).

KIF3C_HUMAN
θ value	4.03905 (rank : 31)	NC score	0.004608 (rank : 43)
Query Neighborhood Hits	40	Target Neighborhood Hits	478	Shared Neighborhood Hits	9
SwissProt Accessions	O14782, O43544	Gene names	KIF3C
Domain Architecture
Description	Kinesin-like protein KIF3C.

DYH5_MOUSE
θ value	5.27518 (rank : 32)	NC score	0.019970 (rank : 24)
Query Neighborhood Hits	40	Target Neighborhood Hits	286	Shared Neighborhood Hits	9
SwissProt Accessions	Q8VHE6, Q8BWG1	Gene names	Dnah5, Dnahc5
Domain Architecture	No domain graphic available
Description	Ciliary dynein heavy chain 5 (Axonemal beta dynein heavy chain 5) (Mdnah5).

IPYR2_HUMAN
θ value	5.27518 (rank : 33)	NC score	0.014597 (rank : 32)
Query Neighborhood Hits	40	Target Neighborhood Hits	7	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H2U2, Q6PG51, Q8TBW0, Q96E55, Q9H0T0, Q9NX37, Q9P033, Q9ULX0	Gene names	PPA2
Domain Architecture	No domain graphic available
Description	Inorganic pyrophosphatase 2, mitochondrial precursor (EC 3.6.1.1) (PPase 2) (Pyrophosphatase SID6-306).

IPYR2_MOUSE
θ value	5.27518 (rank : 34)	NC score	0.014601 (rank : 31)
Query Neighborhood Hits	40	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	Q91VM9, Q3UPK3, Q8BTG5, Q9D1E3	Gene names	Ppa2
Domain Architecture	No domain graphic available
Description	Inorganic pyrophosphatase 2, mitochondrial precursor (EC 3.6.1.1) (PPase 2).

SRPR_HUMAN
θ value	6.88961 (rank : 35)	NC score	0.014033 (rank : 34)
Query Neighborhood Hits	40	Target Neighborhood Hits	42	Shared Neighborhood Hits	3
SwissProt Accessions	P08240, Q9BVJ4	Gene names	SRPR
Domain Architecture
Description	Signal recognition particle receptor subunit alpha (SR-alpha) (Docking protein alpha) (DP-alpha).

SRPR_MOUSE
θ value	6.88961 (rank : 36)	NC score	0.014142 (rank : 33)
Query Neighborhood Hits	40	Target Neighborhood Hits	30	Shared Neighborhood Hits	3
SwissProt Accessions	Q9DBG7, Q8VC45, Q921H1	Gene names	Srpr
Domain Architecture
Description	Signal recognition particle receptor subunit alpha (SR-alpha) (Docking protein alpha) (DP-alpha).

VPS35_HUMAN
θ value	6.88961 (rank : 37)	NC score	0.018785 (rank : 25)
Query Neighborhood Hits	40	Target Neighborhood Hits	24	Shared Neighborhood Hits	4
SwissProt Accessions	Q96QK1, Q561W2, Q9H016, Q9H096, Q9H4P3, Q9H8J0, Q9NRS7, Q9NVG2, Q9NX80, Q9NZK2	Gene names	VPS35, MEM3
Domain Architecture
Description	Vacuolar protein sorting-associated protein 35 (Vesicle protein sorting 35) (hVPS35) (Maternal-embryonic 3).

VPS35_MOUSE
θ value	6.88961 (rank : 38)	NC score	0.018764 (rank : 26)
Query Neighborhood Hits	40	Target Neighborhood Hits	24	Shared Neighborhood Hits	4
SwissProt Accessions	Q9EQH3, Q61123	Gene names	Vps35, Mem3
Domain Architecture
Description	Vacuolar protein sorting-associated protein 35 (Vesicle protein sorting 35) (Maternal-embryonic 3).

GCP6_HUMAN
θ value	8.99809 (rank : 39)	NC score	0.011509 (rank : 36)
Query Neighborhood Hits	40	Target Neighborhood Hits	295	Shared Neighborhood Hits	6
SwissProt Accessions	Q96RT7, Q5JZ80, Q6PJ40, Q86YE9, Q9BY91, Q9UGX3, Q9UGX4	Gene names	TUBGCP6, GCP6, KIAA1669
Domain Architecture
Description	Gamma-tubulin complex component 6 (GCP-6).

RNC_HUMAN
θ value	8.99809 (rank : 40)	NC score	0.008562 (rank : 38)
Query Neighborhood Hits	40	Target Neighborhood Hits	176	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NRR4, Q7Z5V2, Q86YH0, Q9NW73, Q9Y2V9, Q9Y4Y0	Gene names	RNASEN, RN3, RNASE3L
Domain Architecture
Description	Ribonuclease III (EC 3.1.26.3) (RNase III) (Drosha) (p241).

CJ046_HUMAN
θ value	θ > 10 (rank : 41)	NC score	0.079970 (rank : 18)
Query Neighborhood Hits	40	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q86Y37, Q5XPL7, Q8IY11, Q8N7S4	Gene names	C10orf46
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C10orf46.

CJ046_MOUSE
θ value	θ > 10 (rank : 42)	NC score	0.080777 (rank : 17)
Query Neighborhood Hits	40	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R0X2, Q3TE79, Q9CY95	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C10orf46 homolog.

CUL7_HUMAN
θ value	θ > 10 (rank : 43)	NC score	0.088994 (rank : 16)
Query Neighborhood Hits	40	Target Neighborhood Hits	41	Shared Neighborhood Hits	4
SwissProt Accessions	Q14999, Q5T654	Gene names	CUL7, KIAA0076
Domain Architecture
Description	Cullin-7 (CUL-7).

Hits sorted by NC score

CUL4A_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	40	Target Neighborhood Hits	40	Shared Neighborhood Hits	40
SwissProt Accessions	Q13619, O75834, Q589T6, Q5TC62, Q6UP08, Q9UP17	Gene names	CUL4A
Domain Architecture
Description	Cullin-4A (CUL-4A).

CUL4A_MOUSE
NC score	0.998809 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	40	Target Neighborhood Hits	31	Shared Neighborhood Hits	27
SwissProt Accessions	Q3TCH7, Q3THM3, Q91Z44	Gene names	Cul4a
Domain Architecture	No domain graphic available
Description	Cullin-4A (CUL-4A).

CUL4B_HUMAN
NC score	0.993281 (rank : 3)	θ value	0 (rank : 3)
Query Neighborhood Hits	40	Target Neighborhood Hits	80	Shared Neighborhood Hits	21
SwissProt Accessions	Q13620, Q6PIE4, Q6UP07, Q7Z673, Q9BY37, Q9UEB7, Q9UED7	Gene names	CUL4B, KIAA0695
Domain Architecture
Description	Cullin-4B (CUL-4B).

CUL3_MOUSE
NC score	0.958779 (rank : 4)	θ value	1.20704e-137 (rank : 4)
Query Neighborhood Hits	40	Target Neighborhood Hits	39	Shared Neighborhood Hits	14
SwissProt Accessions	Q9JLV5	Gene names	Cul3
Domain Architecture
Description	Cullin-3 (CUL-3).

CUL3_HUMAN
NC score	0.958609 (rank : 5)	θ value	3.51195e-137 (rank : 5)
Query Neighborhood Hits	40	Target Neighborhood Hits	42	Shared Neighborhood Hits	14
SwissProt Accessions	Q13618, O75415, Q569L3, Q9UBI8, Q9UET7	Gene names	CUL3, KIAA0617
Domain Architecture
Description	Cullin-3 (CUL-3).

CUL1_HUMAN
NC score	0.925376 (rank : 6)	θ value	1.2666e-86 (rank : 6)
Query Neighborhood Hits	40	Target Neighborhood Hits	38	Shared Neighborhood Hits	14
SwissProt Accessions	Q13616, O60719, Q8IYW1	Gene names	CUL1
Domain Architecture
Description	Cullin-1 (CUL-1).

CUL1_MOUSE
NC score	0.925367 (rank : 7)	θ value	1.2666e-86 (rank : 7)
Query Neighborhood Hits	40	Target Neighborhood Hits	38	Shared Neighborhood Hits	14
SwissProt Accessions	Q9WTX6, Q9WUI7	Gene names	Cul1
Domain Architecture
Description	Cullin-1 (CUL-1).

CUL2_HUMAN
NC score	0.920137 (rank : 8)	θ value	5.33382e-77 (rank : 8)
Query Neighborhood Hits	40	Target Neighborhood Hits	36	Shared Neighborhood Hits	13
SwissProt Accessions	Q13617, O00200, Q9UNF9	Gene names	CUL2
Domain Architecture
Description	Cullin-2 (CUL-2).

CUL2_MOUSE
NC score	0.919440 (rank : 9)	θ value	2.92676e-75 (rank : 9)
Query Neighborhood Hits	40	Target Neighborhood Hits	29	Shared Neighborhood Hits	13
SwissProt Accessions	Q9D4H8, Q3TUR8	Gene names	Cul2
Domain Architecture
Description	Cullin-2 (CUL-2).

CUL5_MOUSE
NC score	0.890014 (rank : 10)	θ value	2.10721e-57 (rank : 10)
Query Neighborhood Hits	40	Target Neighborhood Hits	41	Shared Neighborhood Hits	13
SwissProt Accessions	Q9D5V5, Q8BMQ6, Q8BV53, Q8C098	Gene names	Cul5
Domain Architecture
Description	Cullin-5 (CUL-5).

CUL5_HUMAN
NC score	0.889418 (rank : 11)	θ value	8.00737e-57 (rank : 11)
Query Neighborhood Hits	40	Target Neighborhood Hits	46	Shared Neighborhood Hits	13
SwissProt Accessions	Q93034, O14766, Q9BZC6	Gene names	CUL5, VACM1
Domain Architecture
Description	Cullin-5 (CUL-5) (Vasopressin-activated calcium-mobilizing receptor) (VACM-1).

ANC2_MOUSE
NC score	0.457123 (rank : 12)	θ value	1.9326e-10 (rank : 13)
Query Neighborhood Hits	40	Target Neighborhood Hits	25	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BZQ7, Q8R2Q1	Gene names	Anapc2
Domain Architecture
Description	Anaphase-promoting complex subunit 2 (APC2) (Cyclosome subunit 2).

ANC2_HUMAN
NC score	0.455190 (rank : 13)	θ value	1.47974e-10 (rank : 12)
Query Neighborhood Hits	40	Target Neighborhood Hits	29	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UJX6, Q5VSG1, Q96DG5, Q96GG4, Q9P2E1	Gene names	ANAPC2, APC2, KIAA1406
Domain Architecture
Description	Anaphase-promoting complex subunit 2 (APC2) (Cyclosome subunit 2).

PARC_HUMAN
NC score	0.118721 (rank : 14)	θ value	0.00175202 (rank : 15)
Query Neighborhood Hits	40	Target Neighborhood Hits	148	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IWT3, O75188, Q68CP2, Q68D92, Q8N3W9, Q9BU56	Gene names	PARC, H7AP1, KIAA0708
Domain Architecture
Description	p53-associated parkin-like cytoplasmic protein (UbcH7-associated protein 1).

PARC_MOUSE
NC score	0.097661 (rank : 15)	θ value	0.00020696 (rank : 14)
Query Neighborhood Hits	40	Target Neighborhood Hits	114	Shared Neighborhood Hits	5
SwissProt Accessions	Q80TT8, Q8BKL9, Q8CGC0, Q8R363	Gene names	Parc, Kiaa0708
Domain Architecture
Description	p53-associated parkin-like cytoplasmic protein.

CUL7_HUMAN
NC score	0.088994 (rank : 16)	θ value	θ > 10 (rank : 43)
Query Neighborhood Hits	40	Target Neighborhood Hits	41	Shared Neighborhood Hits	4
SwissProt Accessions	Q14999, Q5T654	Gene names	CUL7, KIAA0076
Domain Architecture
Description	Cullin-7 (CUL-7).

CJ046_MOUSE
NC score	0.080777 (rank : 17)	θ value	θ > 10 (rank : 42)
Query Neighborhood Hits	40	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R0X2, Q3TE79, Q9CY95	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C10orf46 homolog.

CJ046_HUMAN
NC score	0.079970 (rank : 18)	θ value	θ > 10 (rank : 41)
Query Neighborhood Hits	40	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q86Y37, Q5XPL7, Q8IY11, Q8N7S4	Gene names	C10orf46
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C10orf46.

LAMA2_HUMAN
NC score	0.027305 (rank : 19)	θ value	0.0330416 (rank : 17)
Query Neighborhood Hits	40	Target Neighborhood Hits	1092	Shared Neighborhood Hits	12
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

SACS_MOUSE
NC score	0.025249 (rank : 20)	θ value	2.36792 (rank : 25)
Query Neighborhood Hits	40	Target Neighborhood Hits	99	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JLC8	Gene names	Sacs
Domain Architecture
Description	Sacsin.

SACS_HUMAN
NC score	0.022478 (rank : 21)	θ value	2.36792 (rank : 24)
Query Neighborhood Hits	40	Target Neighborhood Hits	128	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NZJ4, O94835	Gene names	SACS, KIAA0730
Domain Architecture
Description	Sacsin.

LAMA2_MOUSE
NC score	0.021256 (rank : 22)	θ value	0.279714 (rank : 18)
Query Neighborhood Hits	40	Target Neighborhood Hits	1198	Shared Neighborhood Hits	15
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

CP135_HUMAN
NC score	0.020496 (rank : 23)	θ value	0.00869519 (rank : 16)
Query Neighborhood Hits	40	Target Neighborhood Hits	1290	Shared Neighborhood Hits	15
SwissProt Accessions	Q66GS9, O75130, Q9H8H7	Gene names	CEP135, CEP4, KIAA0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

DYH5_MOUSE
NC score	0.019970 (rank : 24)	θ value	5.27518 (rank : 32)
Query Neighborhood Hits	40	Target Neighborhood Hits	286	Shared Neighborhood Hits	9
SwissProt Accessions	Q8VHE6, Q8BWG1	Gene names	Dnah5, Dnahc5
Domain Architecture	No domain graphic available
Description	Ciliary dynein heavy chain 5 (Axonemal beta dynein heavy chain 5) (Mdnah5).

VPS35_HUMAN
NC score	0.018785 (rank : 25)	θ value	6.88961 (rank : 37)
Query Neighborhood Hits	40	Target Neighborhood Hits	24	Shared Neighborhood Hits	4
SwissProt Accessions	Q96QK1, Q561W2, Q9H016, Q9H096, Q9H4P3, Q9H8J0, Q9NRS7, Q9NVG2, Q9NX80, Q9NZK2	Gene names	VPS35, MEM3
Domain Architecture
Description	Vacuolar protein sorting-associated protein 35 (Vesicle protein sorting 35) (hVPS35) (Maternal-embryonic 3).

VPS35_MOUSE
NC score	0.018764 (rank : 26)	θ value	6.88961 (rank : 38)
Query Neighborhood Hits	40	Target Neighborhood Hits	24	Shared Neighborhood Hits	4
SwissProt Accessions	Q9EQH3, Q61123	Gene names	Vps35, Mem3
Domain Architecture
Description	Vacuolar protein sorting-associated protein 35 (Vesicle protein sorting 35) (Maternal-embryonic 3).

DYH5_HUMAN
NC score	0.017618 (rank : 27)	θ value	4.03905 (rank : 28)
Query Neighborhood Hits	40	Target Neighborhood Hits	323	Shared Neighborhood Hits	9
SwissProt Accessions	Q8TE73, Q92860, Q96L74, Q9H5S7, Q9HCG9	Gene names	DNAH5, DNAHC5, KIAA1603
Domain Architecture	No domain graphic available
Description	Ciliary dynein heavy chain 5 (Axonemal beta dynein heavy chain 5) (HL1).

MYH11_MOUSE
NC score	0.017425 (rank : 28)	θ value	0.62314 (rank : 20)
Query Neighborhood Hits	40	Target Neighborhood Hits	1777	Shared Neighborhood Hits	16
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

MYH11_HUMAN
NC score	0.016845 (rank : 29)	θ value	0.47712 (rank : 19)
Query Neighborhood Hits	40	Target Neighborhood Hits	1806	Shared Neighborhood Hits	15
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

MYH14_MOUSE
NC score	0.016276 (rank : 30)	θ value	2.36792 (rank : 23)
Query Neighborhood Hits	40	Target Neighborhood Hits	1225	Shared Neighborhood Hits	16
SwissProt Accessions	Q6URW6, Q80V64, Q80ZE6	Gene names	Myh14
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

IPYR2_MOUSE
NC score	0.014601 (rank : 31)	θ value	5.27518 (rank : 34)
Query Neighborhood Hits	40	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	Q91VM9, Q3UPK3, Q8BTG5, Q9D1E3	Gene names	Ppa2
Domain Architecture	No domain graphic available
Description	Inorganic pyrophosphatase 2, mitochondrial precursor (EC 3.6.1.1) (PPase 2).

IPYR2_HUMAN
NC score	0.014597 (rank : 32)	θ value	5.27518 (rank : 33)
Query Neighborhood Hits	40	Target Neighborhood Hits	7	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H2U2, Q6PG51, Q8TBW0, Q96E55, Q9H0T0, Q9NX37, Q9P033, Q9ULX0	Gene names	PPA2
Domain Architecture	No domain graphic available
Description	Inorganic pyrophosphatase 2, mitochondrial precursor (EC 3.6.1.1) (PPase 2) (Pyrophosphatase SID6-306).

SRPR_MOUSE
NC score	0.014142 (rank : 33)	θ value	6.88961 (rank : 36)
Query Neighborhood Hits	40	Target Neighborhood Hits	30	Shared Neighborhood Hits	3
SwissProt Accessions	Q9DBG7, Q8VC45, Q921H1	Gene names	Srpr
Domain Architecture
Description	Signal recognition particle receptor subunit alpha (SR-alpha) (Docking protein alpha) (DP-alpha).

SRPR_HUMAN
NC score	0.014033 (rank : 34)	θ value	6.88961 (rank : 35)
Query Neighborhood Hits	40	Target Neighborhood Hits	42	Shared Neighborhood Hits	3
SwissProt Accessions	P08240, Q9BVJ4	Gene names	SRPR
Domain Architecture
Description	Signal recognition particle receptor subunit alpha (SR-alpha) (Docking protein alpha) (DP-alpha).

SPTN5_HUMAN
NC score	0.014030 (rank : 35)	θ value	1.38821 (rank : 22)
Query Neighborhood Hits	40	Target Neighborhood Hits	674	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NRC6	Gene names	SPTBN5, SPTBN4
Domain Architecture
Description	Spectrin beta chain, brain 4 (Spectrin, non-erythroid beta chain 4) (Beta-V spectrin) (BSPECV).

GCP6_HUMAN
NC score	0.011509 (rank : 36)	θ value	8.99809 (rank : 39)
Query Neighborhood Hits	40	Target Neighborhood Hits	295	Shared Neighborhood Hits	6
SwissProt Accessions	Q96RT7, Q5JZ80, Q6PJ40, Q86YE9, Q9BY91, Q9UGX3, Q9UGX4	Gene names	TUBGCP6, GCP6, KIAA1669
Domain Architecture
Description	Gamma-tubulin complex component 6 (GCP-6).

REST_HUMAN
NC score	0.009525 (rank : 37)	θ value	1.38821 (rank : 21)
Query Neighborhood Hits	40	Target Neighborhood Hits	1605	Shared Neighborhood Hits	15
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

RNC_HUMAN
NC score	0.008562 (rank : 38)	θ value	8.99809 (rank : 40)
Query Neighborhood Hits	40	Target Neighborhood Hits	176	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NRR4, Q7Z5V2, Q86YH0, Q9NW73, Q9Y2V9, Q9Y4Y0	Gene names	RNASEN, RN3, RNASE3L
Domain Architecture
Description	Ribonuclease III (EC 3.1.26.3) (RNase III) (Drosha) (p241).

TLR3_MOUSE
NC score	0.006934 (rank : 39)	θ value	2.36792 (rank : 26)
Query Neighborhood Hits	40	Target Neighborhood Hits	298	Shared Neighborhood Hits	3
SwissProt Accessions	Q99MB1, Q91ZM4	Gene names	Tlr3
Domain Architecture
Description	Toll-like receptor 3 precursor (CD283 antigen).

TLR3_HUMAN
NC score	0.006407 (rank : 40)	θ value	3.0926 (rank : 27)
Query Neighborhood Hits	40	Target Neighborhood Hits	323	Shared Neighborhood Hits	3
SwissProt Accessions	O15455	Gene names	TLR3
Domain Architecture
Description	Toll-like receptor 3 precursor (CD283 antigen).

K2C6B_HUMAN
NC score	0.005874 (rank : 41)	θ value	4.03905 (rank : 29)
Query Neighborhood Hits	40	Target Neighborhood Hits	526	Shared Neighborhood Hits	10
SwissProt Accessions	P04259, P48669	Gene names	KRT6B, K6B
Domain Architecture
Description	Keratin, type II cytoskeletal 6B (Cytokeratin-6B) (CK 6B) (K6b keratin).

K2C6E_HUMAN
NC score	0.005783 (rank : 42)	θ value	4.03905 (rank : 30)
Query Neighborhood Hits	40	Target Neighborhood Hits	516	Shared Neighborhood Hits	10
SwissProt Accessions	P48668, Q7RTN9	Gene names	KRT6E
Domain Architecture
Description	Keratin, type II cytoskeletal 6E (Cytokeratin-6E) (CK 6E) (K6e keratin) (Keratin K6h).

KIF3C_HUMAN
NC score	0.004608 (rank : 43)	θ value	4.03905 (rank : 31)
Query Neighborhood Hits	40	Target Neighborhood Hits	478	Shared Neighborhood Hits	9
SwissProt Accessions	O14782, O43544	Gene names	KIF3C
Domain Architecture
Description	Kinesin-like protein KIF3C.