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Network neighborhood for query Sequence : CU025_HUMAN

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CU025_HUMAN
SwissProt Accessions	Q9Y426, Q5R2V7, Q6AHX8, Q9NSE6	Gene names	C21orf25, C21orf258
Domain Architecture	No domain graphic available
Description	Protein C21orf25 precursor.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CU025_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	24	Target Neighborhood Hits	24	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y426, Q5R2V7, Q6AHX8, Q9NSE6	Gene names	C21orf25, C21orf258
Domain Architecture	No domain graphic available
Description	Protein C21orf25 precursor.

TMM24_MOUSE
θ value	7.24236e-58 (rank : 2)	NC score	0.842953 (rank : 3)
Query Neighborhood Hits	24	Target Neighborhood Hits	65	Shared Neighborhood Hits	3
SwissProt Accessions	Q80X80	Gene names	Tmem24
Domain Architecture	No domain graphic available
Description	Transmembrane protein 24.

TMM24_HUMAN
θ value	2.18062e-54 (rank : 3)	NC score	0.845990 (rank : 2)
Query Neighborhood Hits	24	Target Neighborhood Hits	37	Shared Neighborhood Hits	3
SwissProt Accessions	O14523, Q86UT7, Q8N522, Q8TBN4, Q96G10	Gene names	TMEM24, KIAA0285
Domain Architecture	No domain graphic available
Description	Transmembrane protein 24 (Protein DLNB23).

FA62A_MOUSE
θ value	0.365318 (rank : 4)	NC score	0.039519 (rank : 4)
Query Neighborhood Hits	24	Target Neighborhood Hits	155	Shared Neighborhood Hits	5
SwissProt Accessions	Q3U7R1, Q8C8R1, Q91X62, Q9CVH0, Q9Z1X5, Q9Z1X6	Gene names	Fam62a, Mbc2
Domain Architecture	No domain graphic available
Description	Protein FAM62A (Membrane-bound C2 domain-containing protein).

SOX13_MOUSE
θ value	0.62314 (rank : 5)	NC score	0.027044 (rank : 10)
Query Neighborhood Hits	24	Target Neighborhood Hits	495	Shared Neighborhood Hits	5
SwissProt Accessions	Q04891, Q922L3	Gene names	Sox13, Sox-13
Domain Architecture
Description	SOX-13 protein.

SON_MOUSE
θ value	1.06291 (rank : 6)	NC score	0.029647 (rank : 8)
Query Neighborhood Hits	24	Target Neighborhood Hits	957	Shared Neighborhood Hits	6
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

ZN672_MOUSE
θ value	1.38821 (rank : 7)	NC score	0.002513 (rank : 24)
Query Neighborhood Hits	24	Target Neighborhood Hits	738	Shared Neighborhood Hits	2
SwissProt Accessions	Q99LH4, Q8BIR7	Gene names	Znf672, Zfp672
Domain Architecture	No domain graphic available
Description	Zinc finger protein 672.

FA47B_HUMAN
θ value	1.81305 (rank : 8)	NC score	0.032131 (rank : 7)
Query Neighborhood Hits	24	Target Neighborhood Hits	431	Shared Neighborhood Hits	7
SwissProt Accessions	Q8NA70, Q5JQN5, Q6PIG3	Gene names	FAM47B
Domain Architecture	No domain graphic available
Description	Protein FAM47B.

BCL10_MOUSE
θ value	3.0926 (rank : 9)	NC score	0.038364 (rank : 5)
Query Neighborhood Hits	24	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z0H7, Q3UBN4	Gene names	Bcl10, Ciper, Clap
Domain Architecture
Description	B-cell lymphoma/leukemia 10 (B-cell CLL/lymphoma 10) (Bcl-10) (CED- 3/ICH-1 prodomain homologous E10-like regulator) (mCIPER) (CARD- containing molecule enhancing NF-kappa-B) (Cellular homolog of vCARMEN) (cCARMEN) (Mammalian CARD-containing adapter molecule E10) (mE10) (Cellular-E10) (c-E10) (CARD-like apoptotic protein) (mCLAP).

SPN90_HUMAN
θ value	3.0926 (rank : 10)	NC score	0.028852 (rank : 9)
Query Neighborhood Hits	24	Target Neighborhood Hits	157	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NZQ3, Q9UGM8	Gene names	NCKIPSD, AF3P21, SPIN90
Domain Architecture
Description	SH3 adapter protein SPIN90 (NCK-interacting protein with SH3 domain) (SH3 protein interacting with Nck, 90 kDa) (VacA-interacting protein, 54 kDa) (VIP54) (AF3p21) (Diaphanous protein-interacting protein) (Dia-interacting protein 1) (DIP-1).

HUWE1_HUMAN
θ value	4.03905 (rank : 11)	NC score	0.012817 (rank : 17)
Query Neighborhood Hits	24	Target Neighborhood Hits	443	Shared Neighborhood Hits	6
SwissProt Accessions	Q7Z6Z7, O15029, Q4G2Z2, Q5H961, Q6P4D0, Q8NG67, Q9BUI0, Q9HCJ4, Q9NSL6, Q9P0A9	Gene names	HUWE1, KIAA0312, KIAA1578, UREB1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (Mcl-1 ubiquitin ligase E3) (Mule) (ARF-binding protein 1) (ARF-BP1).

RPGR1_MOUSE
θ value	4.03905 (rank : 12)	NC score	0.018483 (rank : 15)
Query Neighborhood Hits	24	Target Neighborhood Hits	713	Shared Neighborhood Hits	3
SwissProt Accessions	Q9EPQ2, Q8CAC2, Q8CDJ9, Q91WE0, Q9CUK6, Q9D5Q1	Gene names	Rpgrip1
Domain Architecture	No domain graphic available
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

CTTB2_HUMAN
θ value	5.27518 (rank : 13)	NC score	0.007329 (rank : 22)
Query Neighborhood Hits	24	Target Neighborhood Hits	1061	Shared Neighborhood Hits	5
SwissProt Accessions	Q8WZ74, O43389, Q7LG11, Q9C0A5	Gene names	CTTNBP2, C7orf8, CORTBP2, KIAA1758
Domain Architecture	No domain graphic available
Description	Cortactin-binding protein 2 (CortBP2).

HDGF_HUMAN
θ value	5.27518 (rank : 14)	NC score	0.019812 (rank : 12)
Query Neighborhood Hits	24	Target Neighborhood Hits	61	Shared Neighborhood Hits	2
SwissProt Accessions	P51858, Q5SZ09	Gene names	HDGF, HMG1L2
Domain Architecture
Description	Hepatoma-derived growth factor (HDGF) (High-mobility group protein 1- like 2) (HMG-1L2).

IEX1_HUMAN
θ value	5.27518 (rank : 15)	NC score	0.033780 (rank : 6)
Query Neighborhood Hits	24	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	P46695, Q92691, Q93044	Gene names	IER3, DIF2, IEX1, PRG1
Domain Architecture	No domain graphic available
Description	Radiation-inducible immediate-early gene IEX-1 (Immediate early protein GLY96) (Immediate early response 3 protein) (PACAP-responsive gene 1 protein) (Protein PRG1) (Differentiation-dependent gene 2 protein) (Protein DIF-2).

PCLO_MOUSE
θ value	5.27518 (rank : 16)	NC score	0.012094 (rank : 18)
Query Neighborhood Hits	24	Target Neighborhood Hits	2275	Shared Neighborhood Hits	13
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

ULE1B_MOUSE
θ value	5.27518 (rank : 17)	NC score	0.018954 (rank : 13)
Query Neighborhood Hits	24	Target Neighborhood Hits	56	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z1F9, Q8BVX9	Gene names	Uble1b, Sae2, Uba2
Domain Architecture
Description	Ubiquitin-like 1-activating enzyme E1B (SUMO-1-activating enzyme subunit 2) (Anthracycline-associated resistance ARX).

CN155_HUMAN
θ value	6.88961 (rank : 18)	NC score	0.025159 (rank : 11)
Query Neighborhood Hits	24	Target Neighborhood Hits	385	Shared Neighborhood Hits	8
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

KCNB1_HUMAN
θ value	6.88961 (rank : 19)	NC score	0.006571 (rank : 23)
Query Neighborhood Hits	24	Target Neighborhood Hits	169	Shared Neighborhood Hits	2
SwissProt Accessions	Q14721, Q14193	Gene names	KCNB1
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 1 (Voltage-gated potassium channel subunit Kv2.1) (h-DRK1).

DEN2A_MOUSE
θ value	8.99809 (rank : 20)	NC score	0.009191 (rank : 20)
Query Neighborhood Hits	24	Target Neighborhood Hits	53	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C4S8, Q3TJU2, Q3TUG3, Q3UXA3	Gene names	Dennd2a
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 2A.

MAGE1_HUMAN
θ value	8.99809 (rank : 21)	NC score	0.008490 (rank : 21)
Query Neighborhood Hits	24	Target Neighborhood Hits	1389	Shared Neighborhood Hits	9
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

RFIP1_MOUSE
θ value	8.99809 (rank : 22)	NC score	0.018123 (rank : 16)
Query Neighborhood Hits	24	Target Neighborhood Hits	152	Shared Neighborhood Hits	6
SwissProt Accessions	Q9D620, Q3UBC2, Q8BN24	Gene names	Rab11fip1, Rcp
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

RFIP2_HUMAN
θ value	8.99809 (rank : 23)	NC score	0.018867 (rank : 14)
Query Neighborhood Hits	24	Target Neighborhood Hits	97	Shared Neighborhood Hits	4
SwissProt Accessions	Q7L804, Q9Y2F0	Gene names	RAB11FIP2, KIAA0941
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 2 (Rab11-FIP2) (NRip11).

SIA7A_HUMAN
θ value	8.99809 (rank : 24)	NC score	0.011055 (rank : 19)
Query Neighborhood Hits	24	Target Neighborhood Hits	177	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NSC7, Q6UW90, Q9NSC6	Gene names	ST6GALNAC1, SIAT7A
Domain Architecture
Description	Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 (EC 2.4.99.3) (GalNAc alpha-2,6-sialyltransferase I) (ST6GalNAc I) (Sialyltransferase 7A).

Hits sorted by NC score

CU025_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	24	Target Neighborhood Hits	24	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y426, Q5R2V7, Q6AHX8, Q9NSE6	Gene names	C21orf25, C21orf258
Domain Architecture	No domain graphic available
Description	Protein C21orf25 precursor.

TMM24_HUMAN
NC score	0.845990 (rank : 2)	θ value	2.18062e-54 (rank : 3)
Query Neighborhood Hits	24	Target Neighborhood Hits	37	Shared Neighborhood Hits	3
SwissProt Accessions	O14523, Q86UT7, Q8N522, Q8TBN4, Q96G10	Gene names	TMEM24, KIAA0285
Domain Architecture	No domain graphic available
Description	Transmembrane protein 24 (Protein DLNB23).

TMM24_MOUSE
NC score	0.842953 (rank : 3)	θ value	7.24236e-58 (rank : 2)
Query Neighborhood Hits	24	Target Neighborhood Hits	65	Shared Neighborhood Hits	3
SwissProt Accessions	Q80X80	Gene names	Tmem24
Domain Architecture	No domain graphic available
Description	Transmembrane protein 24.

FA62A_MOUSE
NC score	0.039519 (rank : 4)	θ value	0.365318 (rank : 4)
Query Neighborhood Hits	24	Target Neighborhood Hits	155	Shared Neighborhood Hits	5
SwissProt Accessions	Q3U7R1, Q8C8R1, Q91X62, Q9CVH0, Q9Z1X5, Q9Z1X6	Gene names	Fam62a, Mbc2
Domain Architecture	No domain graphic available
Description	Protein FAM62A (Membrane-bound C2 domain-containing protein).

BCL10_MOUSE
NC score	0.038364 (rank : 5)	θ value	3.0926 (rank : 9)
Query Neighborhood Hits	24	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z0H7, Q3UBN4	Gene names	Bcl10, Ciper, Clap
Domain Architecture
Description	B-cell lymphoma/leukemia 10 (B-cell CLL/lymphoma 10) (Bcl-10) (CED- 3/ICH-1 prodomain homologous E10-like regulator) (mCIPER) (CARD- containing molecule enhancing NF-kappa-B) (Cellular homolog of vCARMEN) (cCARMEN) (Mammalian CARD-containing adapter molecule E10) (mE10) (Cellular-E10) (c-E10) (CARD-like apoptotic protein) (mCLAP).

IEX1_HUMAN
NC score	0.033780 (rank : 6)	θ value	5.27518 (rank : 15)
Query Neighborhood Hits	24	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	P46695, Q92691, Q93044	Gene names	IER3, DIF2, IEX1, PRG1
Domain Architecture	No domain graphic available
Description	Radiation-inducible immediate-early gene IEX-1 (Immediate early protein GLY96) (Immediate early response 3 protein) (PACAP-responsive gene 1 protein) (Protein PRG1) (Differentiation-dependent gene 2 protein) (Protein DIF-2).

FA47B_HUMAN
NC score	0.032131 (rank : 7)	θ value	1.81305 (rank : 8)
Query Neighborhood Hits	24	Target Neighborhood Hits	431	Shared Neighborhood Hits	7
SwissProt Accessions	Q8NA70, Q5JQN5, Q6PIG3	Gene names	FAM47B
Domain Architecture	No domain graphic available
Description	Protein FAM47B.

SON_MOUSE
NC score	0.029647 (rank : 8)	θ value	1.06291 (rank : 6)
Query Neighborhood Hits	24	Target Neighborhood Hits	957	Shared Neighborhood Hits	6
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

SPN90_HUMAN
NC score	0.028852 (rank : 9)	θ value	3.0926 (rank : 10)
Query Neighborhood Hits	24	Target Neighborhood Hits	157	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NZQ3, Q9UGM8	Gene names	NCKIPSD, AF3P21, SPIN90
Domain Architecture
Description	SH3 adapter protein SPIN90 (NCK-interacting protein with SH3 domain) (SH3 protein interacting with Nck, 90 kDa) (VacA-interacting protein, 54 kDa) (VIP54) (AF3p21) (Diaphanous protein-interacting protein) (Dia-interacting protein 1) (DIP-1).

SOX13_MOUSE
NC score	0.027044 (rank : 10)	θ value	0.62314 (rank : 5)
Query Neighborhood Hits	24	Target Neighborhood Hits	495	Shared Neighborhood Hits	5
SwissProt Accessions	Q04891, Q922L3	Gene names	Sox13, Sox-13
Domain Architecture
Description	SOX-13 protein.

CN155_HUMAN
NC score	0.025159 (rank : 11)	θ value	6.88961 (rank : 18)
Query Neighborhood Hits	24	Target Neighborhood Hits	385	Shared Neighborhood Hits	8
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

HDGF_HUMAN
NC score	0.019812 (rank : 12)	θ value	5.27518 (rank : 14)
Query Neighborhood Hits	24	Target Neighborhood Hits	61	Shared Neighborhood Hits	2
SwissProt Accessions	P51858, Q5SZ09	Gene names	HDGF, HMG1L2
Domain Architecture
Description	Hepatoma-derived growth factor (HDGF) (High-mobility group protein 1- like 2) (HMG-1L2).

ULE1B_MOUSE
NC score	0.018954 (rank : 13)	θ value	5.27518 (rank : 17)
Query Neighborhood Hits	24	Target Neighborhood Hits	56	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z1F9, Q8BVX9	Gene names	Uble1b, Sae2, Uba2
Domain Architecture
Description	Ubiquitin-like 1-activating enzyme E1B (SUMO-1-activating enzyme subunit 2) (Anthracycline-associated resistance ARX).

RFIP2_HUMAN
NC score	0.018867 (rank : 14)	θ value	8.99809 (rank : 23)
Query Neighborhood Hits	24	Target Neighborhood Hits	97	Shared Neighborhood Hits	4
SwissProt Accessions	Q7L804, Q9Y2F0	Gene names	RAB11FIP2, KIAA0941
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 2 (Rab11-FIP2) (NRip11).

RPGR1_MOUSE
NC score	0.018483 (rank : 15)	θ value	4.03905 (rank : 12)
Query Neighborhood Hits	24	Target Neighborhood Hits	713	Shared Neighborhood Hits	3
SwissProt Accessions	Q9EPQ2, Q8CAC2, Q8CDJ9, Q91WE0, Q9CUK6, Q9D5Q1	Gene names	Rpgrip1
Domain Architecture	No domain graphic available
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

RFIP1_MOUSE
NC score	0.018123 (rank : 16)	θ value	8.99809 (rank : 22)
Query Neighborhood Hits	24	Target Neighborhood Hits	152	Shared Neighborhood Hits	6
SwissProt Accessions	Q9D620, Q3UBC2, Q8BN24	Gene names	Rab11fip1, Rcp
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

HUWE1_HUMAN
NC score	0.012817 (rank : 17)	θ value	4.03905 (rank : 11)
Query Neighborhood Hits	24	Target Neighborhood Hits	443	Shared Neighborhood Hits	6
SwissProt Accessions	Q7Z6Z7, O15029, Q4G2Z2, Q5H961, Q6P4D0, Q8NG67, Q9BUI0, Q9HCJ4, Q9NSL6, Q9P0A9	Gene names	HUWE1, KIAA0312, KIAA1578, UREB1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (Mcl-1 ubiquitin ligase E3) (Mule) (ARF-binding protein 1) (ARF-BP1).

PCLO_MOUSE
NC score	0.012094 (rank : 18)	θ value	5.27518 (rank : 16)
Query Neighborhood Hits	24	Target Neighborhood Hits	2275	Shared Neighborhood Hits	13
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

SIA7A_HUMAN
NC score	0.011055 (rank : 19)	θ value	8.99809 (rank : 24)
Query Neighborhood Hits	24	Target Neighborhood Hits	177	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NSC7, Q6UW90, Q9NSC6	Gene names	ST6GALNAC1, SIAT7A
Domain Architecture
Description	Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 (EC 2.4.99.3) (GalNAc alpha-2,6-sialyltransferase I) (ST6GalNAc I) (Sialyltransferase 7A).

DEN2A_MOUSE
NC score	0.009191 (rank : 20)	θ value	8.99809 (rank : 20)
Query Neighborhood Hits	24	Target Neighborhood Hits	53	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C4S8, Q3TJU2, Q3TUG3, Q3UXA3	Gene names	Dennd2a
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 2A.

MAGE1_HUMAN
NC score	0.008490 (rank : 21)	θ value	8.99809 (rank : 21)
Query Neighborhood Hits	24	Target Neighborhood Hits	1389	Shared Neighborhood Hits	9
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

CTTB2_HUMAN
NC score	0.007329 (rank : 22)	θ value	5.27518 (rank : 13)
Query Neighborhood Hits	24	Target Neighborhood Hits	1061	Shared Neighborhood Hits	5
SwissProt Accessions	Q8WZ74, O43389, Q7LG11, Q9C0A5	Gene names	CTTNBP2, C7orf8, CORTBP2, KIAA1758
Domain Architecture	No domain graphic available
Description	Cortactin-binding protein 2 (CortBP2).

KCNB1_HUMAN
NC score	0.006571 (rank : 23)	θ value	6.88961 (rank : 19)
Query Neighborhood Hits	24	Target Neighborhood Hits	169	Shared Neighborhood Hits	2
SwissProt Accessions	Q14721, Q14193	Gene names	KCNB1
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 1 (Voltage-gated potassium channel subunit Kv2.1) (h-DRK1).

ZN672_MOUSE
NC score	0.002513 (rank : 24)	θ value	1.38821 (rank : 7)
Query Neighborhood Hits	24	Target Neighborhood Hits	738	Shared Neighborhood Hits	2
SwissProt Accessions	Q99LH4, Q8BIR7	Gene names	Znf672, Zfp672
Domain Architecture	No domain graphic available
Description	Zinc finger protein 672.