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Network neighborhood for query Sequence : IEX1_HUMAN

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IEX1_HUMAN
SwissProt Accessions	P46695, Q92691, Q93044	Gene names	IER3, DIF2, IEX1, PRG1
Domain Architecture	No domain graphic available
Description	Radiation-inducible immediate-early gene IEX-1 (Immediate early protein GLY96) (Immediate early response 3 protein) (PACAP-responsive gene 1 protein) (Protein PRG1) (Differentiation-dependent gene 2 protein) (Protein DIF-2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

IEX1_HUMAN
θ value	8.22888e-78 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	15	Target Neighborhood Hits	15	Shared Neighborhood Hits	15
SwissProt Accessions	P46695, Q92691, Q93044	Gene names	IER3, DIF2, IEX1, PRG1
Domain Architecture	No domain graphic available
Description	Radiation-inducible immediate-early gene IEX-1 (Immediate early protein GLY96) (Immediate early response 3 protein) (PACAP-responsive gene 1 protein) (Protein PRG1) (Differentiation-dependent gene 2 protein) (Protein DIF-2).

IEX1_MOUSE
θ value	1.56274e-52 (rank : 2)	NC score	0.974708 (rank : 2)
Query Neighborhood Hits	15	Target Neighborhood Hits	6	Shared Neighborhood Hits	2
SwissProt Accessions	P46694	Gene names	Ier3, Gly96, Iex1
Domain Architecture	No domain graphic available
Description	Radiation-inducible immediate-early gene IEX-1 (Immediate early protein GLY96) (Immediate early response 3 protein).

JIP3_HUMAN
θ value	0.813845 (rank : 3)	NC score	0.033975 (rank : 4)
Query Neighborhood Hits	15	Target Neighborhood Hits	1039	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UPT6, Q96RY4, Q9H4I4, Q9H7P1, Q9NUG0	Gene names	MAPK8IP3, JIP3, KIAA1066
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3).

RT35_MOUSE
θ value	0.813845 (rank : 4)	NC score	0.068629 (rank : 3)
Query Neighborhood Hits	15	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BJZ4, Q8VCG7	Gene names	Mrps35
Domain Architecture	No domain graphic available
Description	28S ribosomal protein S35, mitochondrial precursor (S35mt) (MRP-S35).

SN1L2_MOUSE
θ value	0.813845 (rank : 5)	NC score	0.007757 (rank : 14)
Query Neighborhood Hits	15	Target Neighborhood Hits	944	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CFH6	Gene names	Snf1lk2, Sik2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SNF1-like kinase 2 (EC 2.7.11.1) (Salt-inducible kinase 2).

MLL2_HUMAN
θ value	1.06291 (rank : 6)	NC score	0.032566 (rank : 7)
Query Neighborhood Hits	15	Target Neighborhood Hits	1788	Shared Neighborhood Hits	7
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

MLL4_HUMAN
θ value	3.0926 (rank : 7)	NC score	0.032964 (rank : 6)
Query Neighborhood Hits	15	Target Neighborhood Hits	722	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

SYNP2_HUMAN
θ value	4.03905 (rank : 8)	NC score	0.025489 (rank : 8)
Query Neighborhood Hits	15	Target Neighborhood Hits	323	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UMS6, Q9UK89	Gene names	SYNPO2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin) (Genethonin 2).

AKP8L_HUMAN
θ value	5.27518 (rank : 9)	NC score	0.024442 (rank : 9)
Query Neighborhood Hits	15	Target Neighborhood Hits	89	Shared Neighborhood Hits	2
SwissProt Accessions	Q9ULX6, O94792, Q96J58, Q9NRQ0, Q9UGM0	Gene names	AKAP8L, NAKAP95
Domain Architecture
Description	A-kinase anchor protein 8-like (AKAP8-like protein) (Neighbor of A- kinase-anchoring protein 95) (Neighbor of AKAP95) (Homologous to AKAP95 protein) (HA95) (Helicase A-binding protein 95) (HAP95).

CU025_HUMAN
θ value	5.27518 (rank : 10)	NC score	0.033780 (rank : 5)
Query Neighborhood Hits	15	Target Neighborhood Hits	24	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y426, Q5R2V7, Q6AHX8, Q9NSE6	Gene names	C21orf25, C21orf258
Domain Architecture	No domain graphic available
Description	Protein C21orf25 precursor.

NACAM_MOUSE
θ value	6.88961 (rank : 11)	NC score	0.015963 (rank : 11)
Query Neighborhood Hits	15	Target Neighborhood Hits	1866	Shared Neighborhood Hits	9
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

BAT2_MOUSE
θ value	8.99809 (rank : 12)	NC score	0.017989 (rank : 10)
Query Neighborhood Hits	15	Target Neighborhood Hits	947	Shared Neighborhood Hits	7
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

COFA1_MOUSE
θ value	8.99809 (rank : 13)	NC score	0.010187 (rank : 12)
Query Neighborhood Hits	15	Target Neighborhood Hits	305	Shared Neighborhood Hits	3
SwissProt Accessions	O35206, Q9EQD9	Gene names	Col15a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XV) chain precursor [Contains: Endostatin (Endostatin-XV)].

GP1BA_HUMAN
θ value	8.99809 (rank : 14)	NC score	0.009480 (rank : 13)
Query Neighborhood Hits	15	Target Neighborhood Hits	407	Shared Neighborhood Hits	5
SwissProt Accessions	P07359, Q14441, Q16469, Q8N1F3, Q8NG39, Q9HDC7, Q9UEK1, Q9UQS4	Gene names	GP1BA
Domain Architecture
Description	Platelet glycoprotein Ib alpha chain precursor (Glycoprotein Ibalpha) (GP-Ib alpha) (GPIbA) (GPIb-alpha) (Antigen CD42b-alpha) (CD42b antigen) [Contains: Glycocalicin].

PTPRJ_HUMAN
θ value	8.99809 (rank : 15)	NC score	0.006758 (rank : 15)
Query Neighborhood Hits	15	Target Neighborhood Hits	207	Shared Neighborhood Hits	2
SwissProt Accessions	Q12913, Q15255, Q8NHM2	Gene names	PTPRJ, DEP1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP eta) (Protein- tyrosine phosphatase receptor type J) (Density-enhanced phosphatase 1) (DEP-1) (CD148 antigen).

Hits sorted by NC score

IEX1_HUMAN
NC score	0.999962 (rank : 1)	θ value	8.22888e-78 (rank : 1)
Query Neighborhood Hits	15	Target Neighborhood Hits	15	Shared Neighborhood Hits	15
SwissProt Accessions	P46695, Q92691, Q93044	Gene names	IER3, DIF2, IEX1, PRG1
Domain Architecture	No domain graphic available
Description	Radiation-inducible immediate-early gene IEX-1 (Immediate early protein GLY96) (Immediate early response 3 protein) (PACAP-responsive gene 1 protein) (Protein PRG1) (Differentiation-dependent gene 2 protein) (Protein DIF-2).

IEX1_MOUSE
NC score	0.974708 (rank : 2)	θ value	1.56274e-52 (rank : 2)
Query Neighborhood Hits	15	Target Neighborhood Hits	6	Shared Neighborhood Hits	2
SwissProt Accessions	P46694	Gene names	Ier3, Gly96, Iex1
Domain Architecture	No domain graphic available
Description	Radiation-inducible immediate-early gene IEX-1 (Immediate early protein GLY96) (Immediate early response 3 protein).

RT35_MOUSE
NC score	0.068629 (rank : 3)	θ value	0.813845 (rank : 4)
Query Neighborhood Hits	15	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BJZ4, Q8VCG7	Gene names	Mrps35
Domain Architecture	No domain graphic available
Description	28S ribosomal protein S35, mitochondrial precursor (S35mt) (MRP-S35).

JIP3_HUMAN
NC score	0.033975 (rank : 4)	θ value	0.813845 (rank : 3)
Query Neighborhood Hits	15	Target Neighborhood Hits	1039	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UPT6, Q96RY4, Q9H4I4, Q9H7P1, Q9NUG0	Gene names	MAPK8IP3, JIP3, KIAA1066
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3).

CU025_HUMAN
NC score	0.033780 (rank : 5)	θ value	5.27518 (rank : 10)
Query Neighborhood Hits	15	Target Neighborhood Hits	24	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y426, Q5R2V7, Q6AHX8, Q9NSE6	Gene names	C21orf25, C21orf258
Domain Architecture	No domain graphic available
Description	Protein C21orf25 precursor.

MLL4_HUMAN
NC score	0.032964 (rank : 6)	θ value	3.0926 (rank : 7)
Query Neighborhood Hits	15	Target Neighborhood Hits	722	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

MLL2_HUMAN
NC score	0.032566 (rank : 7)	θ value	1.06291 (rank : 6)
Query Neighborhood Hits	15	Target Neighborhood Hits	1788	Shared Neighborhood Hits	7
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

SYNP2_HUMAN
NC score	0.025489 (rank : 8)	θ value	4.03905 (rank : 8)
Query Neighborhood Hits	15	Target Neighborhood Hits	323	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UMS6, Q9UK89	Gene names	SYNPO2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin) (Genethonin 2).

AKP8L_HUMAN
NC score	0.024442 (rank : 9)	θ value	5.27518 (rank : 9)
Query Neighborhood Hits	15	Target Neighborhood Hits	89	Shared Neighborhood Hits	2
SwissProt Accessions	Q9ULX6, O94792, Q96J58, Q9NRQ0, Q9UGM0	Gene names	AKAP8L, NAKAP95
Domain Architecture
Description	A-kinase anchor protein 8-like (AKAP8-like protein) (Neighbor of A- kinase-anchoring protein 95) (Neighbor of AKAP95) (Homologous to AKAP95 protein) (HA95) (Helicase A-binding protein 95) (HAP95).

BAT2_MOUSE
NC score	0.017989 (rank : 10)	θ value	8.99809 (rank : 12)
Query Neighborhood Hits	15	Target Neighborhood Hits	947	Shared Neighborhood Hits	7
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

NACAM_MOUSE
NC score	0.015963 (rank : 11)	θ value	6.88961 (rank : 11)
Query Neighborhood Hits	15	Target Neighborhood Hits	1866	Shared Neighborhood Hits	9
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

COFA1_MOUSE
NC score	0.010187 (rank : 12)	θ value	8.99809 (rank : 13)
Query Neighborhood Hits	15	Target Neighborhood Hits	305	Shared Neighborhood Hits	3
SwissProt Accessions	O35206, Q9EQD9	Gene names	Col15a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XV) chain precursor [Contains: Endostatin (Endostatin-XV)].

GP1BA_HUMAN
NC score	0.009480 (rank : 13)	θ value	8.99809 (rank : 14)
Query Neighborhood Hits	15	Target Neighborhood Hits	407	Shared Neighborhood Hits	5
SwissProt Accessions	P07359, Q14441, Q16469, Q8N1F3, Q8NG39, Q9HDC7, Q9UEK1, Q9UQS4	Gene names	GP1BA
Domain Architecture
Description	Platelet glycoprotein Ib alpha chain precursor (Glycoprotein Ibalpha) (GP-Ib alpha) (GPIbA) (GPIb-alpha) (Antigen CD42b-alpha) (CD42b antigen) [Contains: Glycocalicin].

SN1L2_MOUSE
NC score	0.007757 (rank : 14)	θ value	0.813845 (rank : 5)
Query Neighborhood Hits	15	Target Neighborhood Hits	944	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CFH6	Gene names	Snf1lk2, Sik2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SNF1-like kinase 2 (EC 2.7.11.1) (Salt-inducible kinase 2).

PTPRJ_HUMAN
NC score	0.006758 (rank : 15)	θ value	8.99809 (rank : 15)
Query Neighborhood Hits	15	Target Neighborhood Hits	207	Shared Neighborhood Hits	2
SwissProt Accessions	Q12913, Q15255, Q8NHM2	Gene names	PTPRJ, DEP1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP eta) (Protein- tyrosine phosphatase receptor type J) (Density-enhanced phosphatase 1) (DEP-1) (CD148 antigen).