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Network neighborhood for query Sequence : CTLA4_MOUSE

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CTLA4_MOUSE
SwissProt Accessions	P09793, Q9QZZ7	Gene names	Ctla4, Cd152
Domain Architecture
Description	Cytotoxic T-lymphocyte protein 4 precursor (Cytotoxic T-lymphocyte- associated antigen 4) (CTLA-4) (CD152 antigen).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CTLA4_MOUSE
θ value	1.02419e-128 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	21	Target Neighborhood Hits	21	Shared Neighborhood Hits	21
SwissProt Accessions	P09793, Q9QZZ7	Gene names	Ctla4, Cd152
Domain Architecture
Description	Cytotoxic T-lymphocyte protein 4 precursor (Cytotoxic T-lymphocyte- associated antigen 4) (CTLA-4) (CD152 antigen).

CTLA4_HUMAN
θ value	1.26366e-94 (rank : 2)	NC score	0.969838 (rank : 2)
Query Neighborhood Hits	21	Target Neighborhood Hits	51	Shared Neighborhood Hits	12
SwissProt Accessions	P16410, Q53TD5, Q8WXJ1, Q96P43, Q9UKN9	Gene names	CTLA4, CD152
Domain Architecture
Description	Cytotoxic T-lymphocyte protein 4 precursor (Cytotoxic T-lymphocyte- associated antigen 4) (CTLA-4) (CD152 antigen).

CD28_HUMAN
θ value	4.91457e-14 (rank : 3)	NC score	0.636029 (rank : 3)
Query Neighborhood Hits	21	Target Neighborhood Hits	16	Shared Neighborhood Hits	5
SwissProt Accessions	P10747, Q13964, Q8NI54, Q8NI55, Q8NI56, Q8WXJ2, Q9BYV0	Gene names	CD28
Domain Architecture
Description	T-cell-specific surface glycoprotein CD28 precursor (TP44).

CD28_MOUSE
θ value	2.43908e-13 (rank : 4)	NC score	0.628808 (rank : 4)
Query Neighborhood Hits	21	Target Neighborhood Hits	9	Shared Neighborhood Hits	5
SwissProt Accessions	P31041	Gene names	Cd28
Domain Architecture
Description	T-cell-specific surface glycoprotein CD28 precursor.

GPA33_HUMAN
θ value	0.00102713 (rank : 5)	NC score	0.087054 (rank : 10)
Query Neighborhood Hits	21	Target Neighborhood Hits	273	Shared Neighborhood Hits	12
SwissProt Accessions	Q99795	Gene names	GPA33
Domain Architecture
Description	Cell surface A33 antigen precursor (Glycoprotein A33).

NCTR3_HUMAN
θ value	0.00134147 (rank : 6)	NC score	0.293979 (rank : 5)
Query Neighborhood Hits	21	Target Neighborhood Hits	24	Shared Neighborhood Hits	5
SwissProt Accessions	O14931, O14930, O14932, O95667, O95668, O95669, Q5ST89, Q5ST90, Q5ST91, Q5ST92, Q5STA3	Gene names	NCR3, 1C7
Domain Architecture
Description	Natural cytotoxicity triggering receptor 3 precursor (Natural killer cell p30-related protein) (NKp30) (NK-p30) (CD337 antigen).

MPZL1_HUMAN
θ value	0.0193708 (rank : 7)	NC score	0.159557 (rank : 7)
Query Neighborhood Hits	21	Target Neighborhood Hits	41	Shared Neighborhood Hits	8
SwissProt Accessions	O95297, Q5R332, Q8IX11, Q9BWZ3, Q9NYK4, Q9UL20	Gene names	MPZL1, PZR
Domain Architecture	No domain graphic available
Description	Myelin protein zero-like protein 1 precursor (Protein zero-related).

MPZL1_MOUSE
θ value	0.0736092 (rank : 8)	NC score	0.132457 (rank : 8)
Query Neighborhood Hits	21	Target Neighborhood Hits	47	Shared Neighborhood Hits	7
SwissProt Accessions	Q3TEW6, Q2VW02, Q6GQX5	Gene names	Mpzl1, Pzr
Domain Architecture	No domain graphic available
Description	Myelin protein zero-like protein 1 precursor (Protein zero-related).

CD79B_HUMAN
θ value	0.813845 (rank : 9)	NC score	0.061834 (rank : 13)
Query Neighborhood Hits	21	Target Neighborhood Hits	143	Shared Neighborhood Hits	5
SwissProt Accessions	P40259, Q9BU06	Gene names	CD79B, B29, IGB
Domain Architecture
Description	B-cell antigen receptor complex-associated protein beta-chain precursor (B-cell-specific glycoprotein B29) (Immunoglobulin- associated B29 protein) (IG-beta) (CD79b antigen).

ICOS_HUMAN
θ value	0.813845 (rank : 10)	NC score	0.166371 (rank : 6)
Query Neighborhood Hits	21	Target Neighborhood Hits	7	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y6W8, Q8N6W8	Gene names	ICOS, AILIM
Domain Architecture	No domain graphic available
Description	Inducible T-cell co-stimulator precursor (Activation-inducible lymphocyte immunomediatory molecule) (CD278 antigen).

SCN2B_MOUSE
θ value	2.36792 (rank : 11)	NC score	0.067453 (rank : 11)
Query Neighborhood Hits	21	Target Neighborhood Hits	109	Shared Neighborhood Hits	9
SwissProt Accessions	Q56A07	Gene names	Scn2b
Domain Architecture	No domain graphic available
Description	Sodium channel beta-2 subunit precursor.

BTNL8_HUMAN
θ value	3.0926 (rank : 12)	NC score	0.020135 (rank : 18)
Query Neighborhood Hits	21	Target Neighborhood Hits	177	Shared Neighborhood Hits	9
SwissProt Accessions	Q6UX41, Q9H730	Gene names	BTNL8
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 8 precursor.

TIMD3_HUMAN
θ value	3.0926 (rank : 13)	NC score	0.045825 (rank : 15)
Query Neighborhood Hits	21	Target Neighborhood Hits	62	Shared Neighborhood Hits	9
SwissProt Accessions	Q8TDQ0, Q8WW60, Q96K94	Gene names	HAVCR2, TIM3, TIMD3
Domain Architecture	No domain graphic available
Description	Hepatitis A virus cellular receptor 2 precursor (HAVcr-2) (T cell immunoglobulin and mucin domain-containing protein 3) (TIMD-3) (T cell membrane protein 3) (TIM-3).

BT1A1_MOUSE
θ value	5.27518 (rank : 14)	NC score	0.015586 (rank : 19)
Query Neighborhood Hits	21	Target Neighborhood Hits	252	Shared Neighborhood Hits	8
SwissProt Accessions	Q62556, P97392, Q8K2H7, Q921K7	Gene names	Btn1a1, Btn
Domain Architecture
Description	Butyrophilin subfamily 1 member A1 precursor (BT).

CD86_HUMAN
θ value	5.27518 (rank : 15)	NC score	0.028061 (rank : 17)
Query Neighborhood Hits	21	Target Neighborhood Hits	85	Shared Neighborhood Hits	5
SwissProt Accessions	P42081, Q13655, Q7M4L5	Gene names	CD86, CD28LG2
Domain Architecture
Description	T-lymphocyte activation antigen CD86 precursor (Activation B7-2 antigen) (CTLA-4 counter-receptor B7.2) (B70) (FUN-1) (BU63).

DSCAM_HUMAN
θ value	5.27518 (rank : 16)	NC score	0.011800 (rank : 23)
Query Neighborhood Hits	21	Target Neighborhood Hits	524	Shared Neighborhood Hits	10
SwissProt Accessions	O60469, O60468	Gene names	DSCAM
Domain Architecture
Description	Down syndrome cell adhesion molecule precursor (CHD2).

LV2D_HUMAN
θ value	5.27518 (rank : 17)	NC score	0.015273 (rank : 21)
Query Neighborhood Hits	21	Target Neighborhood Hits	231	Shared Neighborhood Hits	5
SwissProt Accessions	P01707	Gene names
Domain Architecture	No domain graphic available
Description	Ig lambda chain V-II region TRO.

PGBM_MOUSE
θ value	6.88961 (rank : 18)	NC score	0.012869 (rank : 22)
Query Neighborhood Hits	21	Target Neighborhood Hits	1073	Shared Neighborhood Hits	9
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

LV2L_HUMAN
θ value	8.99809 (rank : 19)	NC score	0.010231 (rank : 24)
Query Neighborhood Hits	21	Target Neighborhood Hits	224	Shared Neighborhood Hits	7
SwissProt Accessions	P80422	Gene names
Domain Architecture	No domain graphic available
Description	Ig gamma lambda chain V-II region DOT.

TIMD1_MOUSE
θ value	8.99809 (rank : 20)	NC score	0.032268 (rank : 16)
Query Neighborhood Hits	21	Target Neighborhood Hits	97	Shared Neighborhood Hits	9
SwissProt Accessions	Q5QNS5, Q7TPU2, Q8VIM1, Q8VIM2	Gene names	Havcr1, Tim1, Timd1
Domain Architecture	No domain graphic available
Description	Hepatitis A virus cellular receptor 1 homolog precursor (HAVcr-1) (T cell immunoglobulin and mucin domain-containing protein 1) (TIMD-1) (T cell membrane protein 1) (TIM-1).

UT1_HUMAN
θ value	8.99809 (rank : 21)	NC score	0.015568 (rank : 20)
Query Neighborhood Hits	21	Target Neighborhood Hits	7	Shared Neighborhood Hits	2
SwissProt Accessions	Q13336	Gene names	SLC14A1, HUT11, JK, RACH1, UT1, UTE
Domain Architecture
Description	Urea transporter, erythrocyte.

EVA1_HUMAN
θ value	θ > 10 (rank : 22)	NC score	0.051399 (rank : 14)
Query Neighborhood Hits	21	Target Neighborhood Hits	45	Shared Neighborhood Hits	4
SwissProt Accessions	O60487	Gene names	EVA1, EVA
Domain Architecture
Description	Epithelial V-like antigen 1 precursor.

ICOS_MOUSE
θ value	θ > 10 (rank : 23)	NC score	0.122746 (rank : 9)
Query Neighborhood Hits	21	Target Neighborhood Hits	5	Shared Neighborhood Hits	4
SwissProt Accessions	Q9WVS0, Q9JL17	Gene names	Icos, Ailim
Domain Architecture	No domain graphic available
Description	Inducible T-cell co-stimulator precursor (Activation-inducible lymphocyte immunomediatory molecule) (CD28 and CTLA-4-like protein) (CCLP) (CD28-related protein 1) (CRP-1) (CD278 antigen).

SCN2B_HUMAN
θ value	θ > 10 (rank : 24)	NC score	0.063544 (rank : 12)
Query Neighborhood Hits	21	Target Neighborhood Hits	88	Shared Neighborhood Hits	8
SwissProt Accessions	O60939, O75302, Q9UNN3	Gene names	SCN2B
Domain Architecture
Description	Sodium channel beta-2 subunit precursor.

Hits sorted by NC score

CTLA4_MOUSE
NC score	0.999962 (rank : 1)	θ value	1.02419e-128 (rank : 1)
Query Neighborhood Hits	21	Target Neighborhood Hits	21	Shared Neighborhood Hits	21
SwissProt Accessions	P09793, Q9QZZ7	Gene names	Ctla4, Cd152
Domain Architecture
Description	Cytotoxic T-lymphocyte protein 4 precursor (Cytotoxic T-lymphocyte- associated antigen 4) (CTLA-4) (CD152 antigen).

CTLA4_HUMAN
NC score	0.969838 (rank : 2)	θ value	1.26366e-94 (rank : 2)
Query Neighborhood Hits	21	Target Neighborhood Hits	51	Shared Neighborhood Hits	12
SwissProt Accessions	P16410, Q53TD5, Q8WXJ1, Q96P43, Q9UKN9	Gene names	CTLA4, CD152
Domain Architecture
Description	Cytotoxic T-lymphocyte protein 4 precursor (Cytotoxic T-lymphocyte- associated antigen 4) (CTLA-4) (CD152 antigen).

CD28_HUMAN
NC score	0.636029 (rank : 3)	θ value	4.91457e-14 (rank : 3)
Query Neighborhood Hits	21	Target Neighborhood Hits	16	Shared Neighborhood Hits	5
SwissProt Accessions	P10747, Q13964, Q8NI54, Q8NI55, Q8NI56, Q8WXJ2, Q9BYV0	Gene names	CD28
Domain Architecture
Description	T-cell-specific surface glycoprotein CD28 precursor (TP44).

CD28_MOUSE
NC score	0.628808 (rank : 4)	θ value	2.43908e-13 (rank : 4)
Query Neighborhood Hits	21	Target Neighborhood Hits	9	Shared Neighborhood Hits	5
SwissProt Accessions	P31041	Gene names	Cd28
Domain Architecture
Description	T-cell-specific surface glycoprotein CD28 precursor.

NCTR3_HUMAN
NC score	0.293979 (rank : 5)	θ value	0.00134147 (rank : 6)
Query Neighborhood Hits	21	Target Neighborhood Hits	24	Shared Neighborhood Hits	5
SwissProt Accessions	O14931, O14930, O14932, O95667, O95668, O95669, Q5ST89, Q5ST90, Q5ST91, Q5ST92, Q5STA3	Gene names	NCR3, 1C7
Domain Architecture
Description	Natural cytotoxicity triggering receptor 3 precursor (Natural killer cell p30-related protein) (NKp30) (NK-p30) (CD337 antigen).

ICOS_HUMAN
NC score	0.166371 (rank : 6)	θ value	0.813845 (rank : 10)
Query Neighborhood Hits	21	Target Neighborhood Hits	7	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y6W8, Q8N6W8	Gene names	ICOS, AILIM
Domain Architecture	No domain graphic available
Description	Inducible T-cell co-stimulator precursor (Activation-inducible lymphocyte immunomediatory molecule) (CD278 antigen).

MPZL1_HUMAN
NC score	0.159557 (rank : 7)	θ value	0.0193708 (rank : 7)
Query Neighborhood Hits	21	Target Neighborhood Hits	41	Shared Neighborhood Hits	8
SwissProt Accessions	O95297, Q5R332, Q8IX11, Q9BWZ3, Q9NYK4, Q9UL20	Gene names	MPZL1, PZR
Domain Architecture	No domain graphic available
Description	Myelin protein zero-like protein 1 precursor (Protein zero-related).

MPZL1_MOUSE
NC score	0.132457 (rank : 8)	θ value	0.0736092 (rank : 8)
Query Neighborhood Hits	21	Target Neighborhood Hits	47	Shared Neighborhood Hits	7
SwissProt Accessions	Q3TEW6, Q2VW02, Q6GQX5	Gene names	Mpzl1, Pzr
Domain Architecture	No domain graphic available
Description	Myelin protein zero-like protein 1 precursor (Protein zero-related).

ICOS_MOUSE
NC score	0.122746 (rank : 9)	θ value	θ > 10 (rank : 23)
Query Neighborhood Hits	21	Target Neighborhood Hits	5	Shared Neighborhood Hits	4
SwissProt Accessions	Q9WVS0, Q9JL17	Gene names	Icos, Ailim
Domain Architecture	No domain graphic available
Description	Inducible T-cell co-stimulator precursor (Activation-inducible lymphocyte immunomediatory molecule) (CD28 and CTLA-4-like protein) (CCLP) (CD28-related protein 1) (CRP-1) (CD278 antigen).

GPA33_HUMAN
NC score	0.087054 (rank : 10)	θ value	0.00102713 (rank : 5)
Query Neighborhood Hits	21	Target Neighborhood Hits	273	Shared Neighborhood Hits	12
SwissProt Accessions	Q99795	Gene names	GPA33
Domain Architecture
Description	Cell surface A33 antigen precursor (Glycoprotein A33).

SCN2B_MOUSE
NC score	0.067453 (rank : 11)	θ value	2.36792 (rank : 11)
Query Neighborhood Hits	21	Target Neighborhood Hits	109	Shared Neighborhood Hits	9
SwissProt Accessions	Q56A07	Gene names	Scn2b
Domain Architecture	No domain graphic available
Description	Sodium channel beta-2 subunit precursor.

SCN2B_HUMAN
NC score	0.063544 (rank : 12)	θ value	θ > 10 (rank : 24)
Query Neighborhood Hits	21	Target Neighborhood Hits	88	Shared Neighborhood Hits	8
SwissProt Accessions	O60939, O75302, Q9UNN3	Gene names	SCN2B
Domain Architecture
Description	Sodium channel beta-2 subunit precursor.

CD79B_HUMAN
NC score	0.061834 (rank : 13)	θ value	0.813845 (rank : 9)
Query Neighborhood Hits	21	Target Neighborhood Hits	143	Shared Neighborhood Hits	5
SwissProt Accessions	P40259, Q9BU06	Gene names	CD79B, B29, IGB
Domain Architecture
Description	B-cell antigen receptor complex-associated protein beta-chain precursor (B-cell-specific glycoprotein B29) (Immunoglobulin- associated B29 protein) (IG-beta) (CD79b antigen).

EVA1_HUMAN
NC score	0.051399 (rank : 14)	θ value	θ > 10 (rank : 22)
Query Neighborhood Hits	21	Target Neighborhood Hits	45	Shared Neighborhood Hits	4
SwissProt Accessions	O60487	Gene names	EVA1, EVA
Domain Architecture
Description	Epithelial V-like antigen 1 precursor.

TIMD3_HUMAN
NC score	0.045825 (rank : 15)	θ value	3.0926 (rank : 13)
Query Neighborhood Hits	21	Target Neighborhood Hits	62	Shared Neighborhood Hits	9
SwissProt Accessions	Q8TDQ0, Q8WW60, Q96K94	Gene names	HAVCR2, TIM3, TIMD3
Domain Architecture	No domain graphic available
Description	Hepatitis A virus cellular receptor 2 precursor (HAVcr-2) (T cell immunoglobulin and mucin domain-containing protein 3) (TIMD-3) (T cell membrane protein 3) (TIM-3).

TIMD1_MOUSE
NC score	0.032268 (rank : 16)	θ value	8.99809 (rank : 20)
Query Neighborhood Hits	21	Target Neighborhood Hits	97	Shared Neighborhood Hits	9
SwissProt Accessions	Q5QNS5, Q7TPU2, Q8VIM1, Q8VIM2	Gene names	Havcr1, Tim1, Timd1
Domain Architecture	No domain graphic available
Description	Hepatitis A virus cellular receptor 1 homolog precursor (HAVcr-1) (T cell immunoglobulin and mucin domain-containing protein 1) (TIMD-1) (T cell membrane protein 1) (TIM-1).

CD86_HUMAN
NC score	0.028061 (rank : 17)	θ value	5.27518 (rank : 15)
Query Neighborhood Hits	21	Target Neighborhood Hits	85	Shared Neighborhood Hits	5
SwissProt Accessions	P42081, Q13655, Q7M4L5	Gene names	CD86, CD28LG2
Domain Architecture
Description	T-lymphocyte activation antigen CD86 precursor (Activation B7-2 antigen) (CTLA-4 counter-receptor B7.2) (B70) (FUN-1) (BU63).

BTNL8_HUMAN
NC score	0.020135 (rank : 18)	θ value	3.0926 (rank : 12)
Query Neighborhood Hits	21	Target Neighborhood Hits	177	Shared Neighborhood Hits	9
SwissProt Accessions	Q6UX41, Q9H730	Gene names	BTNL8
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 8 precursor.

BT1A1_MOUSE
NC score	0.015586 (rank : 19)	θ value	5.27518 (rank : 14)
Query Neighborhood Hits	21	Target Neighborhood Hits	252	Shared Neighborhood Hits	8
SwissProt Accessions	Q62556, P97392, Q8K2H7, Q921K7	Gene names	Btn1a1, Btn
Domain Architecture
Description	Butyrophilin subfamily 1 member A1 precursor (BT).

UT1_HUMAN
NC score	0.015568 (rank : 20)	θ value	8.99809 (rank : 21)
Query Neighborhood Hits	21	Target Neighborhood Hits	7	Shared Neighborhood Hits	2
SwissProt Accessions	Q13336	Gene names	SLC14A1, HUT11, JK, RACH1, UT1, UTE
Domain Architecture
Description	Urea transporter, erythrocyte.

LV2D_HUMAN
NC score	0.015273 (rank : 21)	θ value	5.27518 (rank : 17)
Query Neighborhood Hits	21	Target Neighborhood Hits	231	Shared Neighborhood Hits	5
SwissProt Accessions	P01707	Gene names
Domain Architecture	No domain graphic available
Description	Ig lambda chain V-II region TRO.

PGBM_MOUSE
NC score	0.012869 (rank : 22)	θ value	6.88961 (rank : 18)
Query Neighborhood Hits	21	Target Neighborhood Hits	1073	Shared Neighborhood Hits	9
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

DSCAM_HUMAN
NC score	0.011800 (rank : 23)	θ value	5.27518 (rank : 16)
Query Neighborhood Hits	21	Target Neighborhood Hits	524	Shared Neighborhood Hits	10
SwissProt Accessions	O60469, O60468	Gene names	DSCAM
Domain Architecture
Description	Down syndrome cell adhesion molecule precursor (CHD2).

LV2L_HUMAN
NC score	0.010231 (rank : 24)	θ value	8.99809 (rank : 19)
Query Neighborhood Hits	21	Target Neighborhood Hits	224	Shared Neighborhood Hits	7
SwissProt Accessions	P80422	Gene names
Domain Architecture	No domain graphic available
Description	Ig gamma lambda chain V-II region DOT.