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Network neighborhood for query Sequence : CD28_HUMAN

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CD28_HUMAN
SwissProt Accessions	P10747, Q13964, Q8NI54, Q8NI55, Q8NI56, Q8WXJ2, Q9BYV0	Gene names	CD28
Domain Architecture
Description	T-cell-specific surface glycoprotein CD28 precursor (TP44).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CD28_HUMAN
θ value	1.33764e-128 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	16	Target Neighborhood Hits	16	Shared Neighborhood Hits	16
SwissProt Accessions	P10747, Q13964, Q8NI54, Q8NI55, Q8NI56, Q8WXJ2, Q9BYV0	Gene names	CD28
Domain Architecture
Description	T-cell-specific surface glycoprotein CD28 precursor (TP44).

CD28_MOUSE
θ value	8.22888e-78 (rank : 2)	NC score	0.979274 (rank : 2)
Query Neighborhood Hits	16	Target Neighborhood Hits	9	Shared Neighborhood Hits	8
SwissProt Accessions	P31041	Gene names	Cd28
Domain Architecture
Description	T-cell-specific surface glycoprotein CD28 precursor.

CTLA4_MOUSE
θ value	4.91457e-14 (rank : 3)	NC score	0.636029 (rank : 3)
Query Neighborhood Hits	16	Target Neighborhood Hits	21	Shared Neighborhood Hits	5
SwissProt Accessions	P09793, Q9QZZ7	Gene names	Ctla4, Cd152
Domain Architecture
Description	Cytotoxic T-lymphocyte protein 4 precursor (Cytotoxic T-lymphocyte- associated antigen 4) (CTLA-4) (CD152 antigen).

CTLA4_HUMAN
θ value	7.09661e-13 (rank : 4)	NC score	0.618323 (rank : 4)
Query Neighborhood Hits	16	Target Neighborhood Hits	51	Shared Neighborhood Hits	6
SwissProt Accessions	P16410, Q53TD5, Q8WXJ1, Q96P43, Q9UKN9	Gene names	CTLA4, CD152
Domain Architecture
Description	Cytotoxic T-lymphocyte protein 4 precursor (Cytotoxic T-lymphocyte- associated antigen 4) (CTLA-4) (CD152 antigen).

ICOS_HUMAN
θ value	5.81887e-07 (rank : 5)	NC score	0.439035 (rank : 5)
Query Neighborhood Hits	16	Target Neighborhood Hits	7	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y6W8, Q8N6W8	Gene names	ICOS, AILIM
Domain Architecture	No domain graphic available
Description	Inducible T-cell co-stimulator precursor (Activation-inducible lymphocyte immunomediatory molecule) (CD278 antigen).

ICOS_MOUSE
θ value	2.44474e-05 (rank : 6)	NC score	0.381747 (rank : 6)
Query Neighborhood Hits	16	Target Neighborhood Hits	5	Shared Neighborhood Hits	5
SwissProt Accessions	Q9WVS0, Q9JL17	Gene names	Icos, Ailim
Domain Architecture	No domain graphic available
Description	Inducible T-cell co-stimulator precursor (Activation-inducible lymphocyte immunomediatory molecule) (CD28 and CTLA-4-like protein) (CCLP) (CD28-related protein 1) (CRP-1) (CD278 antigen).

HV32_MOUSE
θ value	0.365318 (rank : 7)	NC score	0.051296 (rank : 8)
Query Neighborhood Hits	16	Target Neighborhood Hits	204	Shared Neighborhood Hits	10
SwissProt Accessions	P01801	Gene names
Domain Architecture	No domain graphic available
Description	Ig heavy chain V-III region J606.

HV27_MOUSE
θ value	0.62314 (rank : 8)	NC score	0.048211 (rank : 11)
Query Neighborhood Hits	16	Target Neighborhood Hits	202	Shared Neighborhood Hits	9
SwissProt Accessions	P01796	Gene names
Domain Architecture	No domain graphic available
Description	Ig heavy chain V-III region A4.

HV28_MOUSE
θ value	0.62314 (rank : 9)	NC score	0.048515 (rank : 10)
Query Neighborhood Hits	16	Target Neighborhood Hits	197	Shared Neighborhood Hits	9
SwissProt Accessions	P01797	Gene names
Domain Architecture	No domain graphic available
Description	Ig heavy chain V-III region U61.

HV30_MOUSE
θ value	0.62314 (rank : 10)	NC score	0.047400 (rank : 12)
Query Neighborhood Hits	16	Target Neighborhood Hits	216	Shared Neighborhood Hits	9
SwissProt Accessions	P01799	Gene names
Domain Architecture	No domain graphic available
Description	Ig heavy chain V-III region ABE-47N.

ADAM9_HUMAN
θ value	0.813845 (rank : 11)	NC score	0.014241 (rank : 16)
Query Neighborhood Hits	16	Target Neighborhood Hits	243	Shared Neighborhood Hits	2
SwissProt Accessions	Q13443, Q10718, Q8NFM6	Gene names	ADAM9, KIAA0021, MCMP, MDC9, MLTNG
Domain Architecture
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma) (Cellular disintegrin-related protein).

HV33_MOUSE
θ value	1.38821 (rank : 12)	NC score	0.049168 (rank : 9)
Query Neighborhood Hits	16	Target Neighborhood Hits	206	Shared Neighborhood Hits	10
SwissProt Accessions	P01802	Gene names
Domain Architecture	No domain graphic available
Description	Ig heavy chain V-III region W3082.

HV34_MOUSE
θ value	1.38821 (rank : 13)	NC score	0.046687 (rank : 13)
Query Neighborhood Hits	16	Target Neighborhood Hits	209	Shared Neighborhood Hits	9
SwissProt Accessions	P01803	Gene names
Domain Architecture	No domain graphic available
Description	Ig heavy chain V region AMPC1.

HV29_MOUSE
θ value	3.0926 (rank : 14)	NC score	0.045581 (rank : 14)
Query Neighborhood Hits	16	Target Neighborhood Hits	177	Shared Neighborhood Hits	9
SwissProt Accessions	P01798	Gene names
Domain Architecture	No domain graphic available
Description	Ig heavy chain V-III region E109.

LRFN4_HUMAN
θ value	3.0926 (rank : 15)	NC score	0.009043 (rank : 17)
Query Neighborhood Hits	16	Target Neighborhood Hits	462	Shared Neighborhood Hits	2
SwissProt Accessions	Q6PJG9, Q9BWJ0	Gene names	LRFN4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 4 precursor.

HV31_MOUSE
θ value	8.99809 (rank : 16)	NC score	0.042651 (rank : 15)
Query Neighborhood Hits	16	Target Neighborhood Hits	176	Shared Neighborhood Hits	9
SwissProt Accessions	P01800	Gene names
Domain Architecture	No domain graphic available
Description	Ig heavy chain V-III region T957.

NCTR3_HUMAN
θ value	θ > 10 (rank : 17)	NC score	0.075225 (rank : 7)
Query Neighborhood Hits	16	Target Neighborhood Hits	24	Shared Neighborhood Hits	2
SwissProt Accessions	O14931, O14930, O14932, O95667, O95668, O95669, Q5ST89, Q5ST90, Q5ST91, Q5ST92, Q5STA3	Gene names	NCR3, 1C7
Domain Architecture
Description	Natural cytotoxicity triggering receptor 3 precursor (Natural killer cell p30-related protein) (NKp30) (NK-p30) (CD337 antigen).

Hits sorted by NC score

CD28_HUMAN
NC score	0.999962 (rank : 1)	θ value	1.33764e-128 (rank : 1)
Query Neighborhood Hits	16	Target Neighborhood Hits	16	Shared Neighborhood Hits	16
SwissProt Accessions	P10747, Q13964, Q8NI54, Q8NI55, Q8NI56, Q8WXJ2, Q9BYV0	Gene names	CD28
Domain Architecture
Description	T-cell-specific surface glycoprotein CD28 precursor (TP44).

CD28_MOUSE
NC score	0.979274 (rank : 2)	θ value	8.22888e-78 (rank : 2)
Query Neighborhood Hits	16	Target Neighborhood Hits	9	Shared Neighborhood Hits	8
SwissProt Accessions	P31041	Gene names	Cd28
Domain Architecture
Description	T-cell-specific surface glycoprotein CD28 precursor.

CTLA4_MOUSE
NC score	0.636029 (rank : 3)	θ value	4.91457e-14 (rank : 3)
Query Neighborhood Hits	16	Target Neighborhood Hits	21	Shared Neighborhood Hits	5
SwissProt Accessions	P09793, Q9QZZ7	Gene names	Ctla4, Cd152
Domain Architecture
Description	Cytotoxic T-lymphocyte protein 4 precursor (Cytotoxic T-lymphocyte- associated antigen 4) (CTLA-4) (CD152 antigen).

CTLA4_HUMAN
NC score	0.618323 (rank : 4)	θ value	7.09661e-13 (rank : 4)
Query Neighborhood Hits	16	Target Neighborhood Hits	51	Shared Neighborhood Hits	6
SwissProt Accessions	P16410, Q53TD5, Q8WXJ1, Q96P43, Q9UKN9	Gene names	CTLA4, CD152
Domain Architecture
Description	Cytotoxic T-lymphocyte protein 4 precursor (Cytotoxic T-lymphocyte- associated antigen 4) (CTLA-4) (CD152 antigen).

ICOS_HUMAN
NC score	0.439035 (rank : 5)	θ value	5.81887e-07 (rank : 5)
Query Neighborhood Hits	16	Target Neighborhood Hits	7	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y6W8, Q8N6W8	Gene names	ICOS, AILIM
Domain Architecture	No domain graphic available
Description	Inducible T-cell co-stimulator precursor (Activation-inducible lymphocyte immunomediatory molecule) (CD278 antigen).

ICOS_MOUSE
NC score	0.381747 (rank : 6)	θ value	2.44474e-05 (rank : 6)
Query Neighborhood Hits	16	Target Neighborhood Hits	5	Shared Neighborhood Hits	5
SwissProt Accessions	Q9WVS0, Q9JL17	Gene names	Icos, Ailim
Domain Architecture	No domain graphic available
Description	Inducible T-cell co-stimulator precursor (Activation-inducible lymphocyte immunomediatory molecule) (CD28 and CTLA-4-like protein) (CCLP) (CD28-related protein 1) (CRP-1) (CD278 antigen).

NCTR3_HUMAN
NC score	0.075225 (rank : 7)	θ value	θ > 10 (rank : 17)
Query Neighborhood Hits	16	Target Neighborhood Hits	24	Shared Neighborhood Hits	2
SwissProt Accessions	O14931, O14930, O14932, O95667, O95668, O95669, Q5ST89, Q5ST90, Q5ST91, Q5ST92, Q5STA3	Gene names	NCR3, 1C7
Domain Architecture
Description	Natural cytotoxicity triggering receptor 3 precursor (Natural killer cell p30-related protein) (NKp30) (NK-p30) (CD337 antigen).

HV32_MOUSE
NC score	0.051296 (rank : 8)	θ value	0.365318 (rank : 7)
Query Neighborhood Hits	16	Target Neighborhood Hits	204	Shared Neighborhood Hits	10
SwissProt Accessions	P01801	Gene names
Domain Architecture	No domain graphic available
Description	Ig heavy chain V-III region J606.

HV33_MOUSE
NC score	0.049168 (rank : 9)	θ value	1.38821 (rank : 12)
Query Neighborhood Hits	16	Target Neighborhood Hits	206	Shared Neighborhood Hits	10
SwissProt Accessions	P01802	Gene names
Domain Architecture	No domain graphic available
Description	Ig heavy chain V-III region W3082.

HV28_MOUSE
NC score	0.048515 (rank : 10)	θ value	0.62314 (rank : 9)
Query Neighborhood Hits	16	Target Neighborhood Hits	197	Shared Neighborhood Hits	9
SwissProt Accessions	P01797	Gene names
Domain Architecture	No domain graphic available
Description	Ig heavy chain V-III region U61.

HV27_MOUSE
NC score	0.048211 (rank : 11)	θ value	0.62314 (rank : 8)
Query Neighborhood Hits	16	Target Neighborhood Hits	202	Shared Neighborhood Hits	9
SwissProt Accessions	P01796	Gene names
Domain Architecture	No domain graphic available
Description	Ig heavy chain V-III region A4.

HV30_MOUSE
NC score	0.047400 (rank : 12)	θ value	0.62314 (rank : 10)
Query Neighborhood Hits	16	Target Neighborhood Hits	216	Shared Neighborhood Hits	9
SwissProt Accessions	P01799	Gene names
Domain Architecture	No domain graphic available
Description	Ig heavy chain V-III region ABE-47N.

HV34_MOUSE
NC score	0.046687 (rank : 13)	θ value	1.38821 (rank : 13)
Query Neighborhood Hits	16	Target Neighborhood Hits	209	Shared Neighborhood Hits	9
SwissProt Accessions	P01803	Gene names
Domain Architecture	No domain graphic available
Description	Ig heavy chain V region AMPC1.

HV29_MOUSE
NC score	0.045581 (rank : 14)	θ value	3.0926 (rank : 14)
Query Neighborhood Hits	16	Target Neighborhood Hits	177	Shared Neighborhood Hits	9
SwissProt Accessions	P01798	Gene names
Domain Architecture	No domain graphic available
Description	Ig heavy chain V-III region E109.

HV31_MOUSE
NC score	0.042651 (rank : 15)	θ value	8.99809 (rank : 16)
Query Neighborhood Hits	16	Target Neighborhood Hits	176	Shared Neighborhood Hits	9
SwissProt Accessions	P01800	Gene names
Domain Architecture	No domain graphic available
Description	Ig heavy chain V-III region T957.

ADAM9_HUMAN
NC score	0.014241 (rank : 16)	θ value	0.813845 (rank : 11)
Query Neighborhood Hits	16	Target Neighborhood Hits	243	Shared Neighborhood Hits	2
SwissProt Accessions	Q13443, Q10718, Q8NFM6	Gene names	ADAM9, KIAA0021, MCMP, MDC9, MLTNG
Domain Architecture
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma) (Cellular disintegrin-related protein).

LRFN4_HUMAN
NC score	0.009043 (rank : 17)	θ value	3.0926 (rank : 15)
Query Neighborhood Hits	16	Target Neighborhood Hits	462	Shared Neighborhood Hits	2
SwissProt Accessions	Q6PJG9, Q9BWJ0	Gene names	LRFN4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 4 precursor.