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Network neighborhood for query Sequence : ICOS_MOUSE

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ICOS_MOUSE
SwissProt Accessions	Q9WVS0, Q9JL17	Gene names	Icos, Ailim
Domain Architecture	No domain graphic available
Description	Inducible T-cell co-stimulator precursor (Activation-inducible lymphocyte immunomediatory molecule) (CD28 and CTLA-4-like protein) (CCLP) (CD28-related protein 1) (CRP-1) (CD278 antigen).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ICOS_MOUSE
θ value	1.53757e-108 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	5	Target Neighborhood Hits	5	Shared Neighborhood Hits	5
SwissProt Accessions	Q9WVS0, Q9JL17	Gene names	Icos, Ailim
Domain Architecture	No domain graphic available
Description	Inducible T-cell co-stimulator precursor (Activation-inducible lymphocyte immunomediatory molecule) (CD28 and CTLA-4-like protein) (CCLP) (CD28-related protein 1) (CRP-1) (CD278 antigen).

ICOS_HUMAN
θ value	4.08394e-77 (rank : 2)	NC score	0.987181 (rank : 2)
Query Neighborhood Hits	5	Target Neighborhood Hits	7	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y6W8, Q8N6W8	Gene names	ICOS, AILIM
Domain Architecture	No domain graphic available
Description	Inducible T-cell co-stimulator precursor (Activation-inducible lymphocyte immunomediatory molecule) (CD278 antigen).

CD28_HUMAN
θ value	2.44474e-05 (rank : 3)	NC score	0.381747 (rank : 3)
Query Neighborhood Hits	5	Target Neighborhood Hits	16	Shared Neighborhood Hits	5
SwissProt Accessions	P10747, Q13964, Q8NI54, Q8NI55, Q8NI56, Q8WXJ2, Q9BYV0	Gene names	CD28
Domain Architecture
Description	T-cell-specific surface glycoprotein CD28 precursor (TP44).

CD28_MOUSE
θ value	0.00509761 (rank : 4)	NC score	0.340796 (rank : 4)
Query Neighborhood Hits	5	Target Neighborhood Hits	9	Shared Neighborhood Hits	5
SwissProt Accessions	P31041	Gene names	Cd28
Domain Architecture
Description	T-cell-specific surface glycoprotein CD28 precursor.

CTLA4_HUMAN
θ value	0.365318 (rank : 5)	NC score	0.154965 (rank : 5)
Query Neighborhood Hits	5	Target Neighborhood Hits	51	Shared Neighborhood Hits	5
SwissProt Accessions	P16410, Q53TD5, Q8WXJ1, Q96P43, Q9UKN9	Gene names	CTLA4, CD152
Domain Architecture
Description	Cytotoxic T-lymphocyte protein 4 precursor (Cytotoxic T-lymphocyte- associated antigen 4) (CTLA-4) (CD152 antigen).

CTLA4_MOUSE
θ value	θ > 10 (rank : 6)	NC score	0.122746 (rank : 6)
Query Neighborhood Hits	5	Target Neighborhood Hits	21	Shared Neighborhood Hits	4
SwissProt Accessions	P09793, Q9QZZ7	Gene names	Ctla4, Cd152
Domain Architecture
Description	Cytotoxic T-lymphocyte protein 4 precursor (Cytotoxic T-lymphocyte- associated antigen 4) (CTLA-4) (CD152 antigen).

Hits sorted by NC score

ICOS_MOUSE
NC score	0.999962 (rank : 1)	θ value	1.53757e-108 (rank : 1)
Query Neighborhood Hits	5	Target Neighborhood Hits	5	Shared Neighborhood Hits	5
SwissProt Accessions	Q9WVS0, Q9JL17	Gene names	Icos, Ailim
Domain Architecture	No domain graphic available
Description	Inducible T-cell co-stimulator precursor (Activation-inducible lymphocyte immunomediatory molecule) (CD28 and CTLA-4-like protein) (CCLP) (CD28-related protein 1) (CRP-1) (CD278 antigen).

ICOS_HUMAN
NC score	0.987181 (rank : 2)	θ value	4.08394e-77 (rank : 2)
Query Neighborhood Hits	5	Target Neighborhood Hits	7	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y6W8, Q8N6W8	Gene names	ICOS, AILIM
Domain Architecture	No domain graphic available
Description	Inducible T-cell co-stimulator precursor (Activation-inducible lymphocyte immunomediatory molecule) (CD278 antigen).

CD28_HUMAN
NC score	0.381747 (rank : 3)	θ value	2.44474e-05 (rank : 3)
Query Neighborhood Hits	5	Target Neighborhood Hits	16	Shared Neighborhood Hits	5
SwissProt Accessions	P10747, Q13964, Q8NI54, Q8NI55, Q8NI56, Q8WXJ2, Q9BYV0	Gene names	CD28
Domain Architecture
Description	T-cell-specific surface glycoprotein CD28 precursor (TP44).

CD28_MOUSE
NC score	0.340796 (rank : 4)	θ value	0.00509761 (rank : 4)
Query Neighborhood Hits	5	Target Neighborhood Hits	9	Shared Neighborhood Hits	5
SwissProt Accessions	P31041	Gene names	Cd28
Domain Architecture
Description	T-cell-specific surface glycoprotein CD28 precursor.

CTLA4_HUMAN
NC score	0.154965 (rank : 5)	θ value	0.365318 (rank : 5)
Query Neighborhood Hits	5	Target Neighborhood Hits	51	Shared Neighborhood Hits	5
SwissProt Accessions	P16410, Q53TD5, Q8WXJ1, Q96P43, Q9UKN9	Gene names	CTLA4, CD152
Domain Architecture
Description	Cytotoxic T-lymphocyte protein 4 precursor (Cytotoxic T-lymphocyte- associated antigen 4) (CTLA-4) (CD152 antigen).

CTLA4_MOUSE
NC score	0.122746 (rank : 6)	θ value	θ > 10 (rank : 6)
Query Neighborhood Hits	5	Target Neighborhood Hits	21	Shared Neighborhood Hits	4
SwissProt Accessions	P09793, Q9QZZ7	Gene names	Ctla4, Cd152
Domain Architecture
Description	Cytotoxic T-lymphocyte protein 4 precursor (Cytotoxic T-lymphocyte- associated antigen 4) (CTLA-4) (CD152 antigen).