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Network neighborhood for query Sequence : CD5R1_HUMAN

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CD5R1_HUMAN
SwissProt Accessions	Q15078	Gene names	CDK5R1, CDK5R, NCK5A
Domain Architecture
Description	Cyclin-dependent kinase 5 activator 1 precursor (CDK5 activator 1) (Cyclin-dependent kinase 5 regulatory subunit 1) (Tau protein kinase II 23 kDa subunit) (TPKII regulatory subunit) (p23) (p25) (p35) [Contains: Cyclin-dependent kinase 5 activator 1, p35; Cyclin- dependent kinase 5 activator 1, p25].
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CD5R1_MOUSE
θ value	1.85358e-154 (rank : 1)	NC score	0.999439 (rank : 2)
Query Neighborhood Hits	13	Target Neighborhood Hits	13	Shared Neighborhood Hits	12
SwissProt Accessions	P61809, Q62938	Gene names	Cdk5r1, Cdk5r, Nck5a
Domain Architecture
Description	Cyclin-dependent kinase 5 activator 1 precursor (CDK5 activator 1) (Cyclin-dependent kinase 5 regulatory subunit 1) (Tau protein kinase II 23 kDa subunit) (TPKII regulatory subunit) (p23) (p25) (p35) [Contains: Cyclin-dependent kinase 5 activator 1, p35; Cyclin- dependent kinase 5 activator 1, p25].

CD5R1_HUMAN
θ value	4.72459e-150 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	13	Target Neighborhood Hits	13	Shared Neighborhood Hits	13
SwissProt Accessions	Q15078	Gene names	CDK5R1, CDK5R, NCK5A
Domain Architecture
Description	Cyclin-dependent kinase 5 activator 1 precursor (CDK5 activator 1) (Cyclin-dependent kinase 5 regulatory subunit 1) (Tau protein kinase II 23 kDa subunit) (TPKII regulatory subunit) (p23) (p25) (p35) [Contains: Cyclin-dependent kinase 5 activator 1, p35; Cyclin- dependent kinase 5 activator 1, p25].

CD5R2_HUMAN
θ value	2.17557e-62 (rank : 3)	NC score	0.934390 (rank : 3)
Query Neighborhood Hits	13	Target Neighborhood Hits	53	Shared Neighborhood Hits	4
SwissProt Accessions	Q13319, Q4ZFW6	Gene names	CDK5R2, NCK5AI
Domain Architecture
Description	Cyclin-dependent kinase 5 activator 2 precursor (CDK5 activator 2) (Cyclin-dependent kinase 5 regulatory subunit 2) (P39) (P39I).

CD5R2_MOUSE
θ value	4.10295e-61 (rank : 4)	NC score	0.929735 (rank : 4)
Query Neighborhood Hits	13	Target Neighborhood Hits	57	Shared Neighborhood Hits	5
SwissProt Accessions	O35926, O35277	Gene names	Cdk5r2, Nck5ai
Domain Architecture
Description	Cyclin-dependent kinase 5 activator 2 precursor (CDK5 activator 2) (Cyclin-dependent kinase 5 regulatory subunit 2) (P39) (P39I).

CT166_HUMAN
θ value	0.47712 (rank : 5)	NC score	0.134880 (rank : 5)
Query Neighborhood Hits	13	Target Neighborhood Hits	3	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H1L0	Gene names	C20orf166
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf166.

PDZD2_HUMAN
θ value	0.62314 (rank : 6)	NC score	0.026822 (rank : 6)
Query Neighborhood Hits	13	Target Neighborhood Hits	772	Shared Neighborhood Hits	4
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

HGFA_HUMAN
θ value	3.0926 (rank : 7)	NC score	0.009011 (rank : 13)
Query Neighborhood Hits	13	Target Neighborhood Hits	436	Shared Neighborhood Hits	4
SwissProt Accessions	Q04756, Q14726	Gene names	HGFAC
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

CT075_HUMAN
θ value	4.03905 (rank : 8)	NC score	0.017387 (rank : 10)
Query Neighborhood Hits	13	Target Neighborhood Hits	387	Shared Neighborhood Hits	3
SwissProt Accessions	Q8WUT4, Q5JWV6, Q9H419	Gene names	C20orf75
Domain Architecture
Description	Uncharacterized protein C20orf75 precursor.

BIG2_HUMAN
θ value	5.27518 (rank : 9)	NC score	0.016891 (rank : 11)
Query Neighborhood Hits	13	Target Neighborhood Hits	66	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y6D5, Q5TFT9, Q9NTS1	Gene names	ARFGEF2, ARFGEP2, BIG2
Domain Architecture
Description	Brefeldin A-inhibited guanine nucleotide-exchange protein 2 (Brefeldin A-inhibited GEP 2).

TSC2_HUMAN
θ value	5.27518 (rank : 10)	NC score	0.022903 (rank : 7)
Query Neighborhood Hits	13	Target Neighborhood Hits	59	Shared Neighborhood Hits	4
SwissProt Accessions	P49815, O75275, Q8TAZ1	Gene names	TSC2
Domain Architecture
Description	Tuberin (Tuberous sclerosis 2 protein).

CASC5_MOUSE
θ value	6.88961 (rank : 11)	NC score	0.016678 (rank : 12)
Query Neighborhood Hits	13	Target Neighborhood Hits	70	Shared Neighborhood Hits	2
SwissProt Accessions	Q66JQ7, Q8CCH6, Q9CV38	Gene names	Casc5
Domain Architecture	No domain graphic available
Description	Protein CASC5 (Cancer susceptibility candidate gene 5 protein homolog).

IPO7_HUMAN
θ value	6.88961 (rank : 12)	NC score	0.022822 (rank : 8)
Query Neighborhood Hits	13	Target Neighborhood Hits	33	Shared Neighborhood Hits	4
SwissProt Accessions	O95373, Q9H177, Q9NTE3	Gene names	IPO7, RANBP7
Domain Architecture
Description	Importin-7 (Imp7) (Ran-binding protein 7) (RanBP7).

IPO7_MOUSE
θ value	6.88961 (rank : 13)	NC score	0.022796 (rank : 9)
Query Neighborhood Hits	13	Target Neighborhood Hits	34	Shared Neighborhood Hits	4
SwissProt Accessions	Q9EPL8, Q7TN09, Q7TQ63, Q8BKD8, Q8BYI0	Gene names	Ipo7, Ranbp7
Domain Architecture
Description	Importin-7 (Imp7) (Ran-binding protein 7) (RanBP7).

Hits sorted by NC score

CD5R1_HUMAN
NC score	0.999962 (rank : 1)	θ value	4.72459e-150 (rank : 2)
Query Neighborhood Hits	13	Target Neighborhood Hits	13	Shared Neighborhood Hits	13
SwissProt Accessions	Q15078	Gene names	CDK5R1, CDK5R, NCK5A
Domain Architecture
Description	Cyclin-dependent kinase 5 activator 1 precursor (CDK5 activator 1) (Cyclin-dependent kinase 5 regulatory subunit 1) (Tau protein kinase II 23 kDa subunit) (TPKII regulatory subunit) (p23) (p25) (p35) [Contains: Cyclin-dependent kinase 5 activator 1, p35; Cyclin- dependent kinase 5 activator 1, p25].

CD5R1_MOUSE
NC score	0.999439 (rank : 2)	θ value	1.85358e-154 (rank : 1)
Query Neighborhood Hits	13	Target Neighborhood Hits	13	Shared Neighborhood Hits	12
SwissProt Accessions	P61809, Q62938	Gene names	Cdk5r1, Cdk5r, Nck5a
Domain Architecture
Description	Cyclin-dependent kinase 5 activator 1 precursor (CDK5 activator 1) (Cyclin-dependent kinase 5 regulatory subunit 1) (Tau protein kinase II 23 kDa subunit) (TPKII regulatory subunit) (p23) (p25) (p35) [Contains: Cyclin-dependent kinase 5 activator 1, p35; Cyclin- dependent kinase 5 activator 1, p25].

CD5R2_HUMAN
NC score	0.934390 (rank : 3)	θ value	2.17557e-62 (rank : 3)
Query Neighborhood Hits	13	Target Neighborhood Hits	53	Shared Neighborhood Hits	4
SwissProt Accessions	Q13319, Q4ZFW6	Gene names	CDK5R2, NCK5AI
Domain Architecture
Description	Cyclin-dependent kinase 5 activator 2 precursor (CDK5 activator 2) (Cyclin-dependent kinase 5 regulatory subunit 2) (P39) (P39I).

CD5R2_MOUSE
NC score	0.929735 (rank : 4)	θ value	4.10295e-61 (rank : 4)
Query Neighborhood Hits	13	Target Neighborhood Hits	57	Shared Neighborhood Hits	5
SwissProt Accessions	O35926, O35277	Gene names	Cdk5r2, Nck5ai
Domain Architecture
Description	Cyclin-dependent kinase 5 activator 2 precursor (CDK5 activator 2) (Cyclin-dependent kinase 5 regulatory subunit 2) (P39) (P39I).

CT166_HUMAN
NC score	0.134880 (rank : 5)	θ value	0.47712 (rank : 5)
Query Neighborhood Hits	13	Target Neighborhood Hits	3	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H1L0	Gene names	C20orf166
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf166.

PDZD2_HUMAN
NC score	0.026822 (rank : 6)	θ value	0.62314 (rank : 6)
Query Neighborhood Hits	13	Target Neighborhood Hits	772	Shared Neighborhood Hits	4
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

TSC2_HUMAN
NC score	0.022903 (rank : 7)	θ value	5.27518 (rank : 10)
Query Neighborhood Hits	13	Target Neighborhood Hits	59	Shared Neighborhood Hits	4
SwissProt Accessions	P49815, O75275, Q8TAZ1	Gene names	TSC2
Domain Architecture
Description	Tuberin (Tuberous sclerosis 2 protein).

IPO7_HUMAN
NC score	0.022822 (rank : 8)	θ value	6.88961 (rank : 12)
Query Neighborhood Hits	13	Target Neighborhood Hits	33	Shared Neighborhood Hits	4
SwissProt Accessions	O95373, Q9H177, Q9NTE3	Gene names	IPO7, RANBP7
Domain Architecture
Description	Importin-7 (Imp7) (Ran-binding protein 7) (RanBP7).

IPO7_MOUSE
NC score	0.022796 (rank : 9)	θ value	6.88961 (rank : 13)
Query Neighborhood Hits	13	Target Neighborhood Hits	34	Shared Neighborhood Hits	4
SwissProt Accessions	Q9EPL8, Q7TN09, Q7TQ63, Q8BKD8, Q8BYI0	Gene names	Ipo7, Ranbp7
Domain Architecture
Description	Importin-7 (Imp7) (Ran-binding protein 7) (RanBP7).

CT075_HUMAN
NC score	0.017387 (rank : 10)	θ value	4.03905 (rank : 8)
Query Neighborhood Hits	13	Target Neighborhood Hits	387	Shared Neighborhood Hits	3
SwissProt Accessions	Q8WUT4, Q5JWV6, Q9H419	Gene names	C20orf75
Domain Architecture
Description	Uncharacterized protein C20orf75 precursor.

BIG2_HUMAN
NC score	0.016891 (rank : 11)	θ value	5.27518 (rank : 9)
Query Neighborhood Hits	13	Target Neighborhood Hits	66	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y6D5, Q5TFT9, Q9NTS1	Gene names	ARFGEF2, ARFGEP2, BIG2
Domain Architecture
Description	Brefeldin A-inhibited guanine nucleotide-exchange protein 2 (Brefeldin A-inhibited GEP 2).

CASC5_MOUSE
NC score	0.016678 (rank : 12)	θ value	6.88961 (rank : 11)
Query Neighborhood Hits	13	Target Neighborhood Hits	70	Shared Neighborhood Hits	2
SwissProt Accessions	Q66JQ7, Q8CCH6, Q9CV38	Gene names	Casc5
Domain Architecture	No domain graphic available
Description	Protein CASC5 (Cancer susceptibility candidate gene 5 protein homolog).

HGFA_HUMAN
NC score	0.009011 (rank : 13)	θ value	3.0926 (rank : 7)
Query Neighborhood Hits	13	Target Neighborhood Hits	436	Shared Neighborhood Hits	4
SwissProt Accessions	Q04756, Q14726	Gene names	HGFAC
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].