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Network neighborhood for query Sequence : BRCC3_HUMAN

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BRCC3_HUMAN
SwissProt Accessions	P46736, Q16107, Q9BTZ6	Gene names	BRCC3, C6.1A, CXorf53
Domain Architecture
Description	BRCA1/BRCA2-containing complex subunit 3.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

BRCC3_HUMAN
θ value	4.88915e-147 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	18	Target Neighborhood Hits	18	Shared Neighborhood Hits	18
SwissProt Accessions	P46736, Q16107, Q9BTZ6	Gene names	BRCC3, C6.1A, CXorf53
Domain Architecture
Description	BRCA1/BRCA2-containing complex subunit 3.

BRCC3_MOUSE
θ value	5.41814e-138 (rank : 2)	NC score	0.998535 (rank : 2)
Query Neighborhood Hits	18	Target Neighborhood Hits	22	Shared Neighborhood Hits	18
SwissProt Accessions	P46737, Q9D025	Gene names	Brcc3, C6.1A
Domain Architecture
Description	BRCA1/BRCA2-containing complex subunit 3.

PSDE_HUMAN
θ value	4.30538e-10 (rank : 3)	NC score	0.526480 (rank : 3)
Query Neighborhood Hits	18	Target Neighborhood Hits	29	Shared Neighborhood Hits	12
SwissProt Accessions	O00487, O00176	Gene names	PSMD14, POH1
Domain Architecture	No domain graphic available
Description	26S proteasome non-ATPase regulatory subunit 14 (26S proteasome regulatory subunit rpn11) (26S proteasome-associated PAD1 homolog 1).

PSDE_MOUSE
θ value	4.30538e-10 (rank : 4)	NC score	0.526480 (rank : 4)
Query Neighborhood Hits	18	Target Neighborhood Hits	29	Shared Neighborhood Hits	12
SwissProt Accessions	O35593, Q3UB50, Q9CZY6	Gene names	Psmd14, Pad1
Domain Architecture	No domain graphic available
Description	26S proteasome non-ATPase regulatory subunit 14 (26S proteasome regulatory subunit rpn11) (MAD1).

CSN5_HUMAN
θ value	1.09739e-05 (rank : 5)	NC score	0.438254 (rank : 5)
Query Neighborhood Hits	18	Target Neighborhood Hits	18	Shared Neighborhood Hits	12
SwissProt Accessions	Q92905, O15386, Q6AW95, Q86WQ4, Q9BQ17	Gene names	COPS5, CSN5, JAB1
Domain Architecture	No domain graphic available
Description	COP9 signalosome complex subunit 5 (EC 3.4.-.-) (Signalosome subunit 5) (SGN5) (Jun activation domain-binding protein 1).

CSN5_MOUSE
θ value	1.09739e-05 (rank : 6)	NC score	0.438254 (rank : 6)
Query Neighborhood Hits	18	Target Neighborhood Hits	18	Shared Neighborhood Hits	12
SwissProt Accessions	O35864, Q3UA70, Q8C1S1	Gene names	Cops5, Csn5, Jab1, Kic2
Domain Architecture	No domain graphic available
Description	COP9 signalosome complex subunit 5 (EC 3.4.-.-) (Signalosome subunit 5) (SGN5) (Jun activation domain-binding protein 1) (Kip1 C-terminus- interacting protein 2).

MYSM1_HUMAN
θ value	0.00509761 (rank : 7)	NC score	0.236503 (rank : 7)
Query Neighborhood Hits	18	Target Neighborhood Hits	73	Shared Neighborhood Hits	8
SwissProt Accessions	Q5VVJ2, Q7Z3G8, Q96PX3	Gene names	MYSM1, KIAA1915
Domain Architecture	No domain graphic available
Description	Protein MYSM1 (Myb-like, SWIRM and MPN domain-containing protein 1).

MYSM1_MOUSE
θ value	0.00509761 (rank : 8)	NC score	0.229493 (rank : 8)
Query Neighborhood Hits	18	Target Neighborhood Hits	134	Shared Neighborhood Hits	10
SwissProt Accessions	Q69Z66, Q3TPV7, Q8BRP5, Q8C4N1	Gene names	Mysm1, Kiaa1915
Domain Architecture	No domain graphic available
Description	Protein MYSM1 (Myb-like, SWIRM and MPN domain-containing protein 1).

STABP_HUMAN
θ value	0.125558 (rank : 9)	NC score	0.179590 (rank : 11)
Query Neighborhood Hits	18	Target Neighborhood Hits	140	Shared Neighborhood Hits	10
SwissProt Accessions	O95630, Q3MJE7	Gene names	STAMBP, AMSH
Domain Architecture	No domain graphic available
Description	STAM-binding protein (EC 3.1.2.15) (Associated molecule with the SH3 domain of STAM).

STABP_MOUSE
θ value	0.163984 (rank : 10)	NC score	0.170917 (rank : 12)
Query Neighborhood Hits	18	Target Neighborhood Hits	191	Shared Neighborhood Hits	12
SwissProt Accessions	Q9CQ26, Q3UTI9	Gene names	Stambp, Amsh
Domain Architecture	No domain graphic available
Description	STAM-binding protein (EC 3.1.2.15) (Associated molecule with the SH3 domain of STAM).

STALP_HUMAN
θ value	0.279714 (rank : 11)	NC score	0.188927 (rank : 9)
Query Neighborhood Hits	18	Target Neighborhood Hits	36	Shared Neighborhood Hits	10
SwissProt Accessions	Q96FJ0, Q5T9N4, Q5T9N9, Q7Z420, Q9P2H4	Gene names	STAMBPL1, AMSHLP, KIAA1373
Domain Architecture	No domain graphic available
Description	AMSH-like protease (EC 3.1.2.15) (AMSH-LP) (STAM-binding protein-like 1).

STALP_MOUSE
θ value	0.365318 (rank : 12)	NC score	0.186094 (rank : 10)
Query Neighborhood Hits	18	Target Neighborhood Hits	33	Shared Neighborhood Hits	10
SwissProt Accessions	Q76N33, Q76LY0, Q8VEK5	Gene names	Stambpl1, Amshlp
Domain Architecture	No domain graphic available
Description	AMSH-like protease (EC 3.1.2.15) (AMSH-LP) (STAM-binding protein-like 1) (AMSH family protein) (AMSH-FP).

SYNE1_HUMAN
θ value	3.0926 (rank : 13)	NC score	0.016660 (rank : 19)
Query Neighborhood Hits	18	Target Neighborhood Hits	1484	Shared Neighborhood Hits	6
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

AT10A_MOUSE
θ value	6.88961 (rank : 14)	NC score	0.011814 (rank : 22)
Query Neighborhood Hits	18	Target Neighborhood Hits	82	Shared Neighborhood Hits	3
SwissProt Accessions	O54827, Q8R3B8	Gene names	Atp10a, Atpc5, Pfatp
Domain Architecture
Description	Probable phospholipid-transporting ATPase VA (EC 3.6.3.1) (P-locus fat-associated ATPase).

DMD_MOUSE
θ value	6.88961 (rank : 15)	NC score	0.012418 (rank : 21)
Query Neighborhood Hits	18	Target Neighborhood Hits	1111	Shared Neighborhood Hits	6
SwissProt Accessions	P11531, O35653, Q60703	Gene names	Dmd
Domain Architecture
Description	Dystrophin.

RERE_HUMAN
θ value	6.88961 (rank : 16)	NC score	0.020875 (rank : 17)
Query Neighborhood Hits	18	Target Neighborhood Hits	779	Shared Neighborhood Hits	4
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

RERE_MOUSE
θ value	6.88961 (rank : 17)	NC score	0.020528 (rank : 18)
Query Neighborhood Hits	18	Target Neighborhood Hits	785	Shared Neighborhood Hits	4
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

DMD_HUMAN
θ value	8.99809 (rank : 18)	NC score	0.012697 (rank : 20)
Query Neighborhood Hits	18	Target Neighborhood Hits	1135	Shared Neighborhood Hits	7
SwissProt Accessions	P11532, Q02295, Q14169, Q14170, Q5JYU0, Q7KZ48	Gene names	DMD
Domain Architecture
Description	Dystrophin.

IF33_HUMAN
θ value	θ > 10 (rank : 19)	NC score	0.070800 (rank : 14)
Query Neighborhood Hits	18	Target Neighborhood Hits	18	Shared Neighborhood Hits	4
SwissProt Accessions	O15372	Gene names	EIF3S3
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 3 (eIF-3 gamma) (eIF3 p40 subunit) (eIF3h).

IF33_MOUSE
θ value	θ > 10 (rank : 20)	NC score	0.071116 (rank : 13)
Query Neighborhood Hits	18	Target Neighborhood Hits	23	Shared Neighborhood Hits	4
SwissProt Accessions	Q91WK2	Gene names	Eif3s3
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 3 (eIF-3 gamma) (eIF3 p40 subunit) (eIF3h).

PSD7_HUMAN
θ value	θ > 10 (rank : 21)	NC score	0.056553 (rank : 16)
Query Neighborhood Hits	18	Target Neighborhood Hits	29	Shared Neighborhood Hits	4
SwissProt Accessions	P51665, Q6PKI2, Q96E97	Gene names	PSMD7, MOV34L
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 7 (26S proteasome regulatory subunit rpn8) (26S proteasome regulatory subunit S12) (Proteasome subunit p40) (Mov34 protein homolog).

PSD7_MOUSE
θ value	θ > 10 (rank : 22)	NC score	0.056640 (rank : 15)
Query Neighborhood Hits	18	Target Neighborhood Hits	24	Shared Neighborhood Hits	4
SwissProt Accessions	P26516, Q3TW61, Q8C0I8	Gene names	Psmd7, Mov-34, Mov34
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 7 (26S proteasome regulatory subunit rpn8) (26S proteasome regulatory subunit S12) (Proteasome subunit p40) (Mov34 protein).

Hits sorted by NC score

BRCC3_HUMAN
NC score	0.999962 (rank : 1)	θ value	4.88915e-147 (rank : 1)
Query Neighborhood Hits	18	Target Neighborhood Hits	18	Shared Neighborhood Hits	18
SwissProt Accessions	P46736, Q16107, Q9BTZ6	Gene names	BRCC3, C6.1A, CXorf53
Domain Architecture
Description	BRCA1/BRCA2-containing complex subunit 3.

BRCC3_MOUSE
NC score	0.998535 (rank : 2)	θ value	5.41814e-138 (rank : 2)
Query Neighborhood Hits	18	Target Neighborhood Hits	22	Shared Neighborhood Hits	18
SwissProt Accessions	P46737, Q9D025	Gene names	Brcc3, C6.1A
Domain Architecture
Description	BRCA1/BRCA2-containing complex subunit 3.

PSDE_HUMAN
NC score	0.526480 (rank : 3)	θ value	4.30538e-10 (rank : 3)
Query Neighborhood Hits	18	Target Neighborhood Hits	29	Shared Neighborhood Hits	12
SwissProt Accessions	O00487, O00176	Gene names	PSMD14, POH1
Domain Architecture	No domain graphic available
Description	26S proteasome non-ATPase regulatory subunit 14 (26S proteasome regulatory subunit rpn11) (26S proteasome-associated PAD1 homolog 1).

PSDE_MOUSE
NC score	0.526480 (rank : 4)	θ value	4.30538e-10 (rank : 4)
Query Neighborhood Hits	18	Target Neighborhood Hits	29	Shared Neighborhood Hits	12
SwissProt Accessions	O35593, Q3UB50, Q9CZY6	Gene names	Psmd14, Pad1
Domain Architecture	No domain graphic available
Description	26S proteasome non-ATPase regulatory subunit 14 (26S proteasome regulatory subunit rpn11) (MAD1).

CSN5_HUMAN
NC score	0.438254 (rank : 5)	θ value	1.09739e-05 (rank : 5)
Query Neighborhood Hits	18	Target Neighborhood Hits	18	Shared Neighborhood Hits	12
SwissProt Accessions	Q92905, O15386, Q6AW95, Q86WQ4, Q9BQ17	Gene names	COPS5, CSN5, JAB1
Domain Architecture	No domain graphic available
Description	COP9 signalosome complex subunit 5 (EC 3.4.-.-) (Signalosome subunit 5) (SGN5) (Jun activation domain-binding protein 1).

CSN5_MOUSE
NC score	0.438254 (rank : 6)	θ value	1.09739e-05 (rank : 6)
Query Neighborhood Hits	18	Target Neighborhood Hits	18	Shared Neighborhood Hits	12
SwissProt Accessions	O35864, Q3UA70, Q8C1S1	Gene names	Cops5, Csn5, Jab1, Kic2
Domain Architecture	No domain graphic available
Description	COP9 signalosome complex subunit 5 (EC 3.4.-.-) (Signalosome subunit 5) (SGN5) (Jun activation domain-binding protein 1) (Kip1 C-terminus- interacting protein 2).

MYSM1_HUMAN
NC score	0.236503 (rank : 7)	θ value	0.00509761 (rank : 7)
Query Neighborhood Hits	18	Target Neighborhood Hits	73	Shared Neighborhood Hits	8
SwissProt Accessions	Q5VVJ2, Q7Z3G8, Q96PX3	Gene names	MYSM1, KIAA1915
Domain Architecture	No domain graphic available
Description	Protein MYSM1 (Myb-like, SWIRM and MPN domain-containing protein 1).

MYSM1_MOUSE
NC score	0.229493 (rank : 8)	θ value	0.00509761 (rank : 8)
Query Neighborhood Hits	18	Target Neighborhood Hits	134	Shared Neighborhood Hits	10
SwissProt Accessions	Q69Z66, Q3TPV7, Q8BRP5, Q8C4N1	Gene names	Mysm1, Kiaa1915
Domain Architecture	No domain graphic available
Description	Protein MYSM1 (Myb-like, SWIRM and MPN domain-containing protein 1).

STALP_HUMAN
NC score	0.188927 (rank : 9)	θ value	0.279714 (rank : 11)
Query Neighborhood Hits	18	Target Neighborhood Hits	36	Shared Neighborhood Hits	10
SwissProt Accessions	Q96FJ0, Q5T9N4, Q5T9N9, Q7Z420, Q9P2H4	Gene names	STAMBPL1, AMSHLP, KIAA1373
Domain Architecture	No domain graphic available
Description	AMSH-like protease (EC 3.1.2.15) (AMSH-LP) (STAM-binding protein-like 1).

STALP_MOUSE
NC score	0.186094 (rank : 10)	θ value	0.365318 (rank : 12)
Query Neighborhood Hits	18	Target Neighborhood Hits	33	Shared Neighborhood Hits	10
SwissProt Accessions	Q76N33, Q76LY0, Q8VEK5	Gene names	Stambpl1, Amshlp
Domain Architecture	No domain graphic available
Description	AMSH-like protease (EC 3.1.2.15) (AMSH-LP) (STAM-binding protein-like 1) (AMSH family protein) (AMSH-FP).

STABP_HUMAN
NC score	0.179590 (rank : 11)	θ value	0.125558 (rank : 9)
Query Neighborhood Hits	18	Target Neighborhood Hits	140	Shared Neighborhood Hits	10
SwissProt Accessions	O95630, Q3MJE7	Gene names	STAMBP, AMSH
Domain Architecture	No domain graphic available
Description	STAM-binding protein (EC 3.1.2.15) (Associated molecule with the SH3 domain of STAM).

STABP_MOUSE
NC score	0.170917 (rank : 12)	θ value	0.163984 (rank : 10)
Query Neighborhood Hits	18	Target Neighborhood Hits	191	Shared Neighborhood Hits	12
SwissProt Accessions	Q9CQ26, Q3UTI9	Gene names	Stambp, Amsh
Domain Architecture	No domain graphic available
Description	STAM-binding protein (EC 3.1.2.15) (Associated molecule with the SH3 domain of STAM).

IF33_MOUSE
NC score	0.071116 (rank : 13)	θ value	θ > 10 (rank : 20)
Query Neighborhood Hits	18	Target Neighborhood Hits	23	Shared Neighborhood Hits	4
SwissProt Accessions	Q91WK2	Gene names	Eif3s3
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 3 (eIF-3 gamma) (eIF3 p40 subunit) (eIF3h).

IF33_HUMAN
NC score	0.070800 (rank : 14)	θ value	θ > 10 (rank : 19)
Query Neighborhood Hits	18	Target Neighborhood Hits	18	Shared Neighborhood Hits	4
SwissProt Accessions	O15372	Gene names	EIF3S3
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 3 (eIF-3 gamma) (eIF3 p40 subunit) (eIF3h).

PSD7_MOUSE
NC score	0.056640 (rank : 15)	θ value	θ > 10 (rank : 22)
Query Neighborhood Hits	18	Target Neighborhood Hits	24	Shared Neighborhood Hits	4
SwissProt Accessions	P26516, Q3TW61, Q8C0I8	Gene names	Psmd7, Mov-34, Mov34
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 7 (26S proteasome regulatory subunit rpn8) (26S proteasome regulatory subunit S12) (Proteasome subunit p40) (Mov34 protein).

PSD7_HUMAN
NC score	0.056553 (rank : 16)	θ value	θ > 10 (rank : 21)
Query Neighborhood Hits	18	Target Neighborhood Hits	29	Shared Neighborhood Hits	4
SwissProt Accessions	P51665, Q6PKI2, Q96E97	Gene names	PSMD7, MOV34L
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 7 (26S proteasome regulatory subunit rpn8) (26S proteasome regulatory subunit S12) (Proteasome subunit p40) (Mov34 protein homolog).

RERE_HUMAN
NC score	0.020875 (rank : 17)	θ value	6.88961 (rank : 16)
Query Neighborhood Hits	18	Target Neighborhood Hits	779	Shared Neighborhood Hits	4
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

RERE_MOUSE
NC score	0.020528 (rank : 18)	θ value	6.88961 (rank : 17)
Query Neighborhood Hits	18	Target Neighborhood Hits	785	Shared Neighborhood Hits	4
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

SYNE1_HUMAN
NC score	0.016660 (rank : 19)	θ value	3.0926 (rank : 13)
Query Neighborhood Hits	18	Target Neighborhood Hits	1484	Shared Neighborhood Hits	6
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

DMD_HUMAN
NC score	0.012697 (rank : 20)	θ value	8.99809 (rank : 18)
Query Neighborhood Hits	18	Target Neighborhood Hits	1135	Shared Neighborhood Hits	7
SwissProt Accessions	P11532, Q02295, Q14169, Q14170, Q5JYU0, Q7KZ48	Gene names	DMD
Domain Architecture
Description	Dystrophin.

DMD_MOUSE
NC score	0.012418 (rank : 21)	θ value	6.88961 (rank : 15)
Query Neighborhood Hits	18	Target Neighborhood Hits	1111	Shared Neighborhood Hits	6
SwissProt Accessions	P11531, O35653, Q60703	Gene names	Dmd
Domain Architecture
Description	Dystrophin.

AT10A_MOUSE
NC score	0.011814 (rank : 22)	θ value	6.88961 (rank : 14)
Query Neighborhood Hits	18	Target Neighborhood Hits	82	Shared Neighborhood Hits	3
SwissProt Accessions	O54827, Q8R3B8	Gene names	Atp10a, Atpc5, Pfatp
Domain Architecture
Description	Probable phospholipid-transporting ATPase VA (EC 3.6.3.1) (P-locus fat-associated ATPase).