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Network neighborhood for query Sequence : ABEC4_MOUSE

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ABEC4_MOUSE
SwissProt Accessions	Q497M3	Gene names	Apobec4
Domain Architecture	No domain graphic available
Description	Putative C->U-editing enzyme APOBEC-4 (EC 3.5.4.-) (Apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 4).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ABEC4_MOUSE
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	14
SwissProt Accessions	Q497M3	Gene names	Apobec4
Domain Architecture	No domain graphic available
Description	Putative C->U-editing enzyme APOBEC-4 (EC 3.5.4.-) (Apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 4).

ABEC4_HUMAN
θ value	1.16911e-132 (rank : 2)	NC score	0.982628 (rank : 2)
Query Neighborhood Hits	14	Target Neighborhood Hits	11	Shared Neighborhood Hits	6
SwissProt Accessions	Q8WW27, Q8N7F6	Gene names	APOBEC4, C1orf169
Domain Architecture	No domain graphic available
Description	Putative C->U-editing enzyme APOBEC-4 (EC 3.5.4.-) (Apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 4).

ABEC1_MOUSE
θ value	0.0431538 (rank : 3)	NC score	0.117286 (rank : 3)
Query Neighborhood Hits	14	Target Neighborhood Hits	15	Shared Neighborhood Hits	6
SwissProt Accessions	P51908, Q99L67	Gene names	Apobec1
Domain Architecture
Description	C->U-editing enzyme APOBEC-1 (EC 3.5.4.-) (Apolipoprotein B mRNA- editing enzyme 1).

CU058_HUMAN
θ value	1.06291 (rank : 4)	NC score	0.083244 (rank : 4)
Query Neighborhood Hits	14	Target Neighborhood Hits	41	Shared Neighborhood Hits	2
SwissProt Accessions	P58505	Gene names	C21orf58
Domain Architecture	No domain graphic available
Description	Protein C21orf58.

ABC3G_HUMAN
θ value	1.38821 (rank : 5)	NC score	0.065161 (rank : 5)
Query Neighborhood Hits	14	Target Neighborhood Hits	16	Shared Neighborhood Hits	6
SwissProt Accessions	Q9HC16, Q45F02, Q5TF77, Q7Z2N1, Q7Z2N4, Q9H9H8	Gene names	APOBEC3G
Domain Architecture
Description	DNA dC->dU-editing enzyme APOBEC-3G (EC 3.5.4.-) (APOBEC-related cytidine deaminase) (ARCD) (APOBEC-related protein) (ARP-9) (CEM15) (CEM-15).

ABC3B_HUMAN
θ value	3.0926 (rank : 6)	NC score	0.058198 (rank : 7)
Query Neighborhood Hits	14	Target Neighborhood Hits	16	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UH17, O95618, Q5IFJ4, Q7Z2N3, Q7Z6D6, Q9UE74	Gene names	APOBEC3B
Domain Architecture
Description	Probable DNA dC->dU-editing enzyme APOBEC-3B (EC 3.5.4.-) (Phorbolin- 1-related protein) (Phorbolin-2/3).

ITCH_HUMAN
θ value	4.03905 (rank : 7)	NC score	0.013733 (rank : 11)
Query Neighborhood Hits	14	Target Neighborhood Hits	162	Shared Neighborhood Hits	3
SwissProt Accessions	Q96J02, O43584, Q5TEL0, Q96F66, Q9BY75, Q9H451, Q9H4U5	Gene names	ITCH
Domain Architecture
Description	Itchy homolog E3 ubiquitin protein ligase (EC 6.3.2.-) (Itch) (Atrophin-1-interacting protein 4) (AIP4) (NFE2-associated polypeptide 1) (NAPP1).

K1683_HUMAN
θ value	4.03905 (rank : 8)	NC score	0.029602 (rank : 9)
Query Neighborhood Hits	14	Target Neighborhood Hits	240	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H0B3, Q8N4G8, Q96M14, Q9C0I0	Gene names	KIAA1683
Domain Architecture	No domain graphic available
Description	Protein KIAA1683.

SNPH_HUMAN
θ value	5.27518 (rank : 9)	NC score	0.022455 (rank : 10)
Query Neighborhood Hits	14	Target Neighborhood Hits	236	Shared Neighborhood Hits	2
SwissProt Accessions	O15079	Gene names	SNPH, KIAA0374
Domain Architecture	No domain graphic available
Description	Syntaphilin.

ABC3F_HUMAN
θ value	6.88961 (rank : 10)	NC score	0.053472 (rank : 8)
Query Neighborhood Hits	14	Target Neighborhood Hits	16	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IUX4, Q45F03, Q7Z2N2, Q7Z2N5	Gene names	APOBEC3F
Domain Architecture
Description	DNA dC->dU-editing enzyme APOBEC-3F (EC 3.5.4.-) (Apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3F).

BRWD1_HUMAN
θ value	6.88961 (rank : 11)	NC score	0.008354 (rank : 14)
Query Neighborhood Hits	14	Target Neighborhood Hits	448	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NSI6, O43721, Q5R2V0, Q5R2V1, Q8TCV3, Q96QG9, Q96QH0, Q9NUK1	Gene names	BRWD1, C21orf107, WDR9
Domain Architecture
Description	Bromodomain and WD repeat domain-containing protein 1 (WD repeat protein 9).

SHPS1_MOUSE
θ value	6.88961 (rank : 12)	NC score	0.011289 (rank : 13)
Query Neighborhood Hits	14	Target Neighborhood Hits	439	Shared Neighborhood Hits	3
SwissProt Accessions	P97797, O08907, O35924, O88555, O88556, P97796, Q8R559, Q9QX57, Q9WTN4	Gene names	Sirpa, Bit, Myd1, Ptpns1, Shps1, Sirp
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type substrate 1 precursor (SHP substrate 1) (SHPS-1) (Inhibitory receptor SHPS-1) (Signal- regulatory protein alpha-1) (Sirp-alpha-1) (mSIRP-alpha1) (MyD-1 antigen) (Brain Ig-like molecule with tyrosine-based activation motifs) (Bit) (p84) (CD172a antigen).

ITCH_MOUSE
θ value	8.99809 (rank : 13)	NC score	0.011816 (rank : 12)
Query Neighborhood Hits	14	Target Neighborhood Hits	127	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C863, O54971	Gene names	Itch
Domain Architecture
Description	Itchy E3 ubiquitin protein ligase (EC 6.3.2.-).

TITIN_HUMAN
θ value	8.99809 (rank : 14)	NC score	0.001568 (rank : 15)
Query Neighborhood Hits	14	Target Neighborhood Hits	2923	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

ABEC1_HUMAN
θ value	θ > 10 (rank : 15)	NC score	0.061391 (rank : 6)
Query Neighborhood Hits	14	Target Neighborhood Hits	15	Shared Neighborhood Hits	5
SwissProt Accessions	P41238, Q9UE64, Q9UM71	Gene names	APOBEC1
Domain Architecture
Description	C->U-editing enzyme APOBEC-1 (EC 3.5.4.-) (Apolipoprotein B mRNA- editing enzyme 1) (HEPR).

Hits sorted by NC score

ABEC4_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	14
SwissProt Accessions	Q497M3	Gene names	Apobec4
Domain Architecture	No domain graphic available
Description	Putative C->U-editing enzyme APOBEC-4 (EC 3.5.4.-) (Apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 4).

ABEC4_HUMAN
NC score	0.982628 (rank : 2)	θ value	1.16911e-132 (rank : 2)
Query Neighborhood Hits	14	Target Neighborhood Hits	11	Shared Neighborhood Hits	6
SwissProt Accessions	Q8WW27, Q8N7F6	Gene names	APOBEC4, C1orf169
Domain Architecture	No domain graphic available
Description	Putative C->U-editing enzyme APOBEC-4 (EC 3.5.4.-) (Apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 4).

ABEC1_MOUSE
NC score	0.117286 (rank : 3)	θ value	0.0431538 (rank : 3)
Query Neighborhood Hits	14	Target Neighborhood Hits	15	Shared Neighborhood Hits	6
SwissProt Accessions	P51908, Q99L67	Gene names	Apobec1
Domain Architecture
Description	C->U-editing enzyme APOBEC-1 (EC 3.5.4.-) (Apolipoprotein B mRNA- editing enzyme 1).

CU058_HUMAN
NC score	0.083244 (rank : 4)	θ value	1.06291 (rank : 4)
Query Neighborhood Hits	14	Target Neighborhood Hits	41	Shared Neighborhood Hits	2
SwissProt Accessions	P58505	Gene names	C21orf58
Domain Architecture	No domain graphic available
Description	Protein C21orf58.

ABC3G_HUMAN
NC score	0.065161 (rank : 5)	θ value	1.38821 (rank : 5)
Query Neighborhood Hits	14	Target Neighborhood Hits	16	Shared Neighborhood Hits	6
SwissProt Accessions	Q9HC16, Q45F02, Q5TF77, Q7Z2N1, Q7Z2N4, Q9H9H8	Gene names	APOBEC3G
Domain Architecture
Description	DNA dC->dU-editing enzyme APOBEC-3G (EC 3.5.4.-) (APOBEC-related cytidine deaminase) (ARCD) (APOBEC-related protein) (ARP-9) (CEM15) (CEM-15).

ABEC1_HUMAN
NC score	0.061391 (rank : 6)	θ value	θ > 10 (rank : 15)
Query Neighborhood Hits	14	Target Neighborhood Hits	15	Shared Neighborhood Hits	5
SwissProt Accessions	P41238, Q9UE64, Q9UM71	Gene names	APOBEC1
Domain Architecture
Description	C->U-editing enzyme APOBEC-1 (EC 3.5.4.-) (Apolipoprotein B mRNA- editing enzyme 1) (HEPR).

ABC3B_HUMAN
NC score	0.058198 (rank : 7)	θ value	3.0926 (rank : 6)
Query Neighborhood Hits	14	Target Neighborhood Hits	16	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UH17, O95618, Q5IFJ4, Q7Z2N3, Q7Z6D6, Q9UE74	Gene names	APOBEC3B
Domain Architecture
Description	Probable DNA dC->dU-editing enzyme APOBEC-3B (EC 3.5.4.-) (Phorbolin- 1-related protein) (Phorbolin-2/3).

ABC3F_HUMAN
NC score	0.053472 (rank : 8)	θ value	6.88961 (rank : 10)
Query Neighborhood Hits	14	Target Neighborhood Hits	16	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IUX4, Q45F03, Q7Z2N2, Q7Z2N5	Gene names	APOBEC3F
Domain Architecture
Description	DNA dC->dU-editing enzyme APOBEC-3F (EC 3.5.4.-) (Apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3F).

K1683_HUMAN
NC score	0.029602 (rank : 9)	θ value	4.03905 (rank : 8)
Query Neighborhood Hits	14	Target Neighborhood Hits	240	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H0B3, Q8N4G8, Q96M14, Q9C0I0	Gene names	KIAA1683
Domain Architecture	No domain graphic available
Description	Protein KIAA1683.

SNPH_HUMAN
NC score	0.022455 (rank : 10)	θ value	5.27518 (rank : 9)
Query Neighborhood Hits	14	Target Neighborhood Hits	236	Shared Neighborhood Hits	2
SwissProt Accessions	O15079	Gene names	SNPH, KIAA0374
Domain Architecture	No domain graphic available
Description	Syntaphilin.

ITCH_HUMAN
NC score	0.013733 (rank : 11)	θ value	4.03905 (rank : 7)
Query Neighborhood Hits	14	Target Neighborhood Hits	162	Shared Neighborhood Hits	3
SwissProt Accessions	Q96J02, O43584, Q5TEL0, Q96F66, Q9BY75, Q9H451, Q9H4U5	Gene names	ITCH
Domain Architecture
Description	Itchy homolog E3 ubiquitin protein ligase (EC 6.3.2.-) (Itch) (Atrophin-1-interacting protein 4) (AIP4) (NFE2-associated polypeptide 1) (NAPP1).

ITCH_MOUSE
NC score	0.011816 (rank : 12)	θ value	8.99809 (rank : 13)
Query Neighborhood Hits	14	Target Neighborhood Hits	127	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C863, O54971	Gene names	Itch
Domain Architecture
Description	Itchy E3 ubiquitin protein ligase (EC 6.3.2.-).

SHPS1_MOUSE
NC score	0.011289 (rank : 13)	θ value	6.88961 (rank : 12)
Query Neighborhood Hits	14	Target Neighborhood Hits	439	Shared Neighborhood Hits	3
SwissProt Accessions	P97797, O08907, O35924, O88555, O88556, P97796, Q8R559, Q9QX57, Q9WTN4	Gene names	Sirpa, Bit, Myd1, Ptpns1, Shps1, Sirp
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type substrate 1 precursor (SHP substrate 1) (SHPS-1) (Inhibitory receptor SHPS-1) (Signal- regulatory protein alpha-1) (Sirp-alpha-1) (mSIRP-alpha1) (MyD-1 antigen) (Brain Ig-like molecule with tyrosine-based activation motifs) (Bit) (p84) (CD172a antigen).

BRWD1_HUMAN
NC score	0.008354 (rank : 14)	θ value	6.88961 (rank : 11)
Query Neighborhood Hits	14	Target Neighborhood Hits	448	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NSI6, O43721, Q5R2V0, Q5R2V1, Q8TCV3, Q96QG9, Q96QH0, Q9NUK1	Gene names	BRWD1, C21orf107, WDR9
Domain Architecture
Description	Bromodomain and WD repeat domain-containing protein 1 (WD repeat protein 9).

TITIN_HUMAN
NC score	0.001568 (rank : 15)	θ value	8.99809 (rank : 14)
Query Neighborhood Hits	14	Target Neighborhood Hits	2923	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).