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Network neighborhood for query Sequence : 2A5B_HUMAN

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2A5B_HUMAN
SwissProt Accessions	Q15173, Q13853	Gene names	PPP2R5B
Domain Architecture
Description	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform (PP2A, B subunit, B' beta isoform) (PP2A, B subunit, B56 beta isoform) (PP2A, B subunit, PR61 beta isoform) (PP2A, B subunit, R5 beta isoform).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

2A5B_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	13	Target Neighborhood Hits	13	Shared Neighborhood Hits	13
SwissProt Accessions	Q15173, Q13853	Gene names	PPP2R5B
Domain Architecture
Description	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform (PP2A, B subunit, B' beta isoform) (PP2A, B subunit, B56 beta isoform) (PP2A, B subunit, PR61 beta isoform) (PP2A, B subunit, R5 beta isoform).

2A5E_HUMAN
θ value	5.52945e-183 (rank : 2)	NC score	0.998601 (rank : 2)
Query Neighborhood Hits	13	Target Neighborhood Hits	11	Shared Neighborhood Hits	9
SwissProt Accessions	Q16537	Gene names	PPP2R5E
Domain Architecture
Description	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform (PP2A, B subunit, B' epsilon isoform) (PP2A, B subunit, B56 epsilon isoform) (PP2A, B subunit, PR61 epsilon isoform) (PP2A, B subunit, R5 epsilon isoform).

2A5E_MOUSE
θ value	7.22167e-183 (rank : 3)	NC score	0.998600 (rank : 3)
Query Neighborhood Hits	13	Target Neighborhood Hits	11	Shared Neighborhood Hits	9
SwissProt Accessions	Q61151, Q3V1I5, Q571M6, Q8C2M2	Gene names	Ppp2r5e, Kiaa4006
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform (PP2A, B subunit, B' epsilon isoform) (PP2A, B subunit, B56 epsilon isoform) (PP2A, B subunit, PR61 epsilon isoform) (PP2A, B subunit, R5 epsilon isoform).

2A5D_HUMAN
θ value	2.7506e-174 (rank : 4)	NC score	0.992026 (rank : 8)
Query Neighborhood Hits	13	Target Neighborhood Hits	59	Shared Neighborhood Hits	8
SwissProt Accessions	Q14738, O00494, O00696, Q15171	Gene names	PPP2R5D
Domain Architecture
Description	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform (PP2A, B subunit, B' delta isoform) (PP2A, B subunit, B56 delta isoform) (PP2A, B subunit, PR61 delta isoform) (PP2A, B subunit, R5 delta isoform).

2A5A_MOUSE
θ value	5.73535e-172 (rank : 5)	NC score	0.997922 (rank : 4)
Query Neighborhood Hits	13	Target Neighborhood Hits	15	Shared Neighborhood Hits	9
SwissProt Accessions	Q6PD03, Q8R1U7	Gene names	Ppp2r5a
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform (PP2A, B subunit, B' alpha isoform) (PP2A, B subunit, B56 alpha isoform) (PP2A, B subunit, PR61 alpha isoform) (PP2A, B subunit, R5 alpha isoform) (PR61alpha).

2A5A_HUMAN
θ value	3.71755e-171 (rank : 6)	NC score	0.997757 (rank : 5)
Query Neighborhood Hits	13	Target Neighborhood Hits	13	Shared Neighborhood Hits	9
SwissProt Accessions	Q15172, Q5VVB2, Q8TBI9	Gene names	PPP2R5A
Domain Architecture
Description	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform (PP2A, B subunit, B' alpha isoform) (PP2A, B subunit, B56 alpha isoform) (PP2A, B subunit, PR61 alpha isoform) (PP2A, B subunit, R5 alpha isoform).

2A5G_HUMAN
θ value	1.20145e-153 (rank : 7)	NC score	0.993029 (rank : 7)
Query Neighborhood Hits	13	Target Neighborhood Hits	22	Shared Neighborhood Hits	8
SwissProt Accessions	Q13362, Q14391, Q15060, Q15174	Gene names	PPP2R5C, KIAA0044
Domain Architecture
Description	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform (PP2A, B subunit, B' gamma isoform) (PP2A, B subunit, B56 gamma isoform) (PP2A, B subunit, PR61 gamma isoform) (PP2A, B subunit, R5 gamma isoform) (NY-REN-29 antigen).

2A5G_MOUSE
θ value	2.67656e-153 (rank : 8)	NC score	0.993122 (rank : 6)
Query Neighborhood Hits	13	Target Neighborhood Hits	25	Shared Neighborhood Hits	8
SwissProt Accessions	Q60996, O35708, Q99KW8, Q99N67, Q99N68	Gene names	Ppp2r5c
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform (PP2A, B subunit, B' gamma isoform) (PP2A, B subunit, B56 gamma isoform) (PP2A, B subunit, PR61 gamma isoform) (PP2A, B subunit, R5 gamma isoform) (PP2A, B subunit, B'alpha3 isoform).

TCF25_MOUSE
θ value	1.81305 (rank : 9)	NC score	0.019803 (rank : 9)
Query Neighborhood Hits	13	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R3L2, Q3THR8, Q3UBI7, Q3UD64, Q3UG75, Q80ZX3, Q8BR80, Q8C200, Q8C2M3, Q8C6B4, Q9CUW0, Q9ER19	Gene names	Tcf25, D8Ertd325e, Nulp1
Domain Architecture
Description	Transcription factor 25 (Nuclear localized protein 1).

MICA1_HUMAN
θ value	2.36792 (rank : 10)	NC score	0.008914 (rank : 10)
Query Neighborhood Hits	13	Target Neighborhood Hits	279	Shared Neighborhood Hits	2
SwissProt Accessions	Q8TDZ2, Q7Z633, Q8IVS9, Q96G47, Q9H6X6, Q9H7I0, Q9HAA1, Q9UFF7	Gene names	MICAL1, MICAL, NICAL
Domain Architecture
Description	NEDD9-interacting protein with calponin homology and LIM domains (Molecule interacting with CasL protein 1).

TGM5_HUMAN
θ value	3.0926 (rank : 11)	NC score	0.007212 (rank : 11)
Query Neighborhood Hits	13	Target Neighborhood Hits	30	Shared Neighborhood Hits	2
SwissProt Accessions	O43548, O43549, Q9UEZ4	Gene names	TGM5, TGMX
Domain Architecture
Description	Protein-glutamine gamma-glutamyltransferase 5 (EC 2.3.2.13) (Transglutaminase-5) (TGase 5) (Transglutaminase X) (TGase X) (TGX) (TG(X)).

ZFP27_MOUSE
θ value	3.0926 (rank : 12)	NC score	0.002145 (rank : 12)
Query Neighborhood Hits	13	Target Neighborhood Hits	764	Shared Neighborhood Hits	6
SwissProt Accessions	P10077, Q6PCZ6, Q8CED4	Gene names	Zfp27, Mkr4, Zfp-27
Domain Architecture	No domain graphic available
Description	Zinc finger protein 27 (Zfp-27) (Protein mKR4).

SMC2_HUMAN
θ value	4.03905 (rank : 13)	NC score	0.001869 (rank : 13)
Query Neighborhood Hits	13	Target Neighborhood Hits	1405	Shared Neighborhood Hits	2
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

Hits sorted by NC score

2A5B_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	13	Target Neighborhood Hits	13	Shared Neighborhood Hits	13
SwissProt Accessions	Q15173, Q13853	Gene names	PPP2R5B
Domain Architecture
Description	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform (PP2A, B subunit, B' beta isoform) (PP2A, B subunit, B56 beta isoform) (PP2A, B subunit, PR61 beta isoform) (PP2A, B subunit, R5 beta isoform).

2A5E_HUMAN
NC score	0.998601 (rank : 2)	θ value	5.52945e-183 (rank : 2)
Query Neighborhood Hits	13	Target Neighborhood Hits	11	Shared Neighborhood Hits	9
SwissProt Accessions	Q16537	Gene names	PPP2R5E
Domain Architecture
Description	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform (PP2A, B subunit, B' epsilon isoform) (PP2A, B subunit, B56 epsilon isoform) (PP2A, B subunit, PR61 epsilon isoform) (PP2A, B subunit, R5 epsilon isoform).

2A5E_MOUSE
NC score	0.998600 (rank : 3)	θ value	7.22167e-183 (rank : 3)
Query Neighborhood Hits	13	Target Neighborhood Hits	11	Shared Neighborhood Hits	9
SwissProt Accessions	Q61151, Q3V1I5, Q571M6, Q8C2M2	Gene names	Ppp2r5e, Kiaa4006
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform (PP2A, B subunit, B' epsilon isoform) (PP2A, B subunit, B56 epsilon isoform) (PP2A, B subunit, PR61 epsilon isoform) (PP2A, B subunit, R5 epsilon isoform).

2A5A_MOUSE
NC score	0.997922 (rank : 4)	θ value	5.73535e-172 (rank : 5)
Query Neighborhood Hits	13	Target Neighborhood Hits	15	Shared Neighborhood Hits	9
SwissProt Accessions	Q6PD03, Q8R1U7	Gene names	Ppp2r5a
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform (PP2A, B subunit, B' alpha isoform) (PP2A, B subunit, B56 alpha isoform) (PP2A, B subunit, PR61 alpha isoform) (PP2A, B subunit, R5 alpha isoform) (PR61alpha).

2A5A_HUMAN
NC score	0.997757 (rank : 5)	θ value	3.71755e-171 (rank : 6)
Query Neighborhood Hits	13	Target Neighborhood Hits	13	Shared Neighborhood Hits	9
SwissProt Accessions	Q15172, Q5VVB2, Q8TBI9	Gene names	PPP2R5A
Domain Architecture
Description	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform (PP2A, B subunit, B' alpha isoform) (PP2A, B subunit, B56 alpha isoform) (PP2A, B subunit, PR61 alpha isoform) (PP2A, B subunit, R5 alpha isoform).

2A5G_MOUSE
NC score	0.993122 (rank : 6)	θ value	2.67656e-153 (rank : 8)
Query Neighborhood Hits	13	Target Neighborhood Hits	25	Shared Neighborhood Hits	8
SwissProt Accessions	Q60996, O35708, Q99KW8, Q99N67, Q99N68	Gene names	Ppp2r5c
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform (PP2A, B subunit, B' gamma isoform) (PP2A, B subunit, B56 gamma isoform) (PP2A, B subunit, PR61 gamma isoform) (PP2A, B subunit, R5 gamma isoform) (PP2A, B subunit, B'alpha3 isoform).

2A5G_HUMAN
NC score	0.993029 (rank : 7)	θ value	1.20145e-153 (rank : 7)
Query Neighborhood Hits	13	Target Neighborhood Hits	22	Shared Neighborhood Hits	8
SwissProt Accessions	Q13362, Q14391, Q15060, Q15174	Gene names	PPP2R5C, KIAA0044
Domain Architecture
Description	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform (PP2A, B subunit, B' gamma isoform) (PP2A, B subunit, B56 gamma isoform) (PP2A, B subunit, PR61 gamma isoform) (PP2A, B subunit, R5 gamma isoform) (NY-REN-29 antigen).

2A5D_HUMAN
NC score	0.992026 (rank : 8)	θ value	2.7506e-174 (rank : 4)
Query Neighborhood Hits	13	Target Neighborhood Hits	59	Shared Neighborhood Hits	8
SwissProt Accessions	Q14738, O00494, O00696, Q15171	Gene names	PPP2R5D
Domain Architecture
Description	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform (PP2A, B subunit, B' delta isoform) (PP2A, B subunit, B56 delta isoform) (PP2A, B subunit, PR61 delta isoform) (PP2A, B subunit, R5 delta isoform).

TCF25_MOUSE
NC score	0.019803 (rank : 9)	θ value	1.81305 (rank : 9)
Query Neighborhood Hits	13	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R3L2, Q3THR8, Q3UBI7, Q3UD64, Q3UG75, Q80ZX3, Q8BR80, Q8C200, Q8C2M3, Q8C6B4, Q9CUW0, Q9ER19	Gene names	Tcf25, D8Ertd325e, Nulp1
Domain Architecture
Description	Transcription factor 25 (Nuclear localized protein 1).

MICA1_HUMAN
NC score	0.008914 (rank : 10)	θ value	2.36792 (rank : 10)
Query Neighborhood Hits	13	Target Neighborhood Hits	279	Shared Neighborhood Hits	2
SwissProt Accessions	Q8TDZ2, Q7Z633, Q8IVS9, Q96G47, Q9H6X6, Q9H7I0, Q9HAA1, Q9UFF7	Gene names	MICAL1, MICAL, NICAL
Domain Architecture
Description	NEDD9-interacting protein with calponin homology and LIM domains (Molecule interacting with CasL protein 1).

TGM5_HUMAN
NC score	0.007212 (rank : 11)	θ value	3.0926 (rank : 11)
Query Neighborhood Hits	13	Target Neighborhood Hits	30	Shared Neighborhood Hits	2
SwissProt Accessions	O43548, O43549, Q9UEZ4	Gene names	TGM5, TGMX
Domain Architecture
Description	Protein-glutamine gamma-glutamyltransferase 5 (EC 2.3.2.13) (Transglutaminase-5) (TGase 5) (Transglutaminase X) (TGase X) (TGX) (TG(X)).

ZFP27_MOUSE
NC score	0.002145 (rank : 12)	θ value	3.0926 (rank : 12)
Query Neighborhood Hits	13	Target Neighborhood Hits	764	Shared Neighborhood Hits	6
SwissProt Accessions	P10077, Q6PCZ6, Q8CED4	Gene names	Zfp27, Mkr4, Zfp-27
Domain Architecture	No domain graphic available
Description	Zinc finger protein 27 (Zfp-27) (Protein mKR4).

SMC2_HUMAN
NC score	0.001869 (rank : 13)	θ value	4.03905 (rank : 13)
Query Neighborhood Hits	13	Target Neighborhood Hits	1405	Shared Neighborhood Hits	2
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).