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Network neighborhood for query Sequence : UXS1_HUMAN

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UXS1_HUMAN
SwissProt Accessions	Q8NBZ7, Q8NBX3, Q9H5C2	Gene names	UXS1
Domain Architecture	No domain graphic available
Description	UDP-glucuronic acid decarboxylase 1 (EC 4.1.1.35) (UDP-glucuronate decarboxylase 1) (UGD) (UXS-1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

UXS1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	19	Target Neighborhood Hits	19	Shared Neighborhood Hits	19
SwissProt Accessions	Q8NBZ7, Q8NBX3, Q9H5C2	Gene names	UXS1
Domain Architecture	No domain graphic available
Description	UDP-glucuronic acid decarboxylase 1 (EC 4.1.1.35) (UDP-glucuronate decarboxylase 1) (UGD) (UXS-1).

UXS1_MOUSE
θ value	0 (rank : 2)	NC score	0.999958 (rank : 2)
Query Neighborhood Hits	19	Target Neighborhood Hits	19	Shared Neighborhood Hits	19
SwissProt Accessions	Q91XL3, Q3U854	Gene names	Uxs1
Domain Architecture	No domain graphic available
Description	UDP-glucuronic acid decarboxylase 1 (EC 4.1.1.35) (UDP-glucuronate decarboxylase 1) (UGD) (UXS-1).

TGDS_MOUSE
θ value	2.77775e-25 (rank : 3)	NC score	0.717765 (rank : 3)
Query Neighborhood Hits	19	Target Neighborhood Hits	26	Shared Neighborhood Hits	14
SwissProt Accessions	Q8VDR7	Gene names	Tgds
Domain Architecture
Description	dTDP-D-glucose 4,6-dehydratase (EC 4.2.1.46).

TGDS_HUMAN
θ value	1.5242e-23 (rank : 4)	NC score	0.710963 (rank : 4)
Query Neighborhood Hits	19	Target Neighborhood Hits	23	Shared Neighborhood Hits	14
SwissProt Accessions	O95455, Q5T3Z2, Q9H1T9	Gene names	TGDS
Domain Architecture
Description	dTDP-D-glucose 4,6-dehydratase (EC 4.2.1.46).

GALE_HUMAN
θ value	1.86753e-13 (rank : 5)	NC score	0.604834 (rank : 6)
Query Neighborhood Hits	19	Target Neighborhood Hits	25	Shared Neighborhood Hits	14
SwissProt Accessions	Q14376, Q86W41, Q9BVE3, Q9UJB4	Gene names	GALE
Domain Architecture
Description	UDP-glucose 4-epimerase (EC 5.1.3.2) (Galactowaldenase) (UDP-galactose 4-epimerase).

GALE_MOUSE
θ value	2.43908e-13 (rank : 6)	NC score	0.605868 (rank : 5)
Query Neighborhood Hits	19	Target Neighborhood Hits	28	Shared Neighborhood Hits	14
SwissProt Accessions	Q8R059	Gene names	Gale
Domain Architecture
Description	UDP-glucose 4-epimerase (EC 5.1.3.2) (Galactowaldenase) (UDP-galactose 4-epimerase).

FCL_HUMAN
θ value	7.09661e-13 (rank : 7)	NC score	0.548135 (rank : 7)
Query Neighborhood Hits	19	Target Neighborhood Hits	11	Shared Neighborhood Hits	8
SwissProt Accessions	Q13630, Q567Q9, Q9UDG7	Gene names	TSTA3
Domain Architecture
Description	GDP-L-fucose synthetase (EC 1.1.1.271) (Protein FX) (Red cell NADP(H)- binding protein) (GDP-4-keto-6-deoxy-D-mannose-3,5-epimerase-4- reductase).

NSDHL_HUMAN
θ value	3.52202e-12 (rank : 8)	NC score	0.398869 (rank : 12)
Query Neighborhood Hits	19	Target Neighborhood Hits	27	Shared Neighborhood Hits	10
SwissProt Accessions	Q15738, O00344	Gene names	NSDHL, H105E3
Domain Architecture
Description	Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating (EC 1.1.1.170) (H105e3 protein).

FCL_MOUSE
θ value	2.28291e-11 (rank : 9)	NC score	0.528097 (rank : 8)
Query Neighborhood Hits	19	Target Neighborhood Hits	10	Shared Neighborhood Hits	8
SwissProt Accessions	P23591	Gene names	Tsta3, P35b, Tstap35b
Domain Architecture
Description	GDP-L-fucose synthetase (EC 1.1.1.271) (Protein FX) (Red cell NADP(H)- binding protein) (GDP-4-keto-6-deoxy-D-mannose-3,5-epimerase-4- reductase) (Transplantation antigen P35B) (Tum-P35B antigen).

NSDHL_MOUSE
θ value	2.28291e-11 (rank : 10)	NC score	0.399929 (rank : 11)
Query Neighborhood Hits	19	Target Neighborhood Hits	25	Shared Neighborhood Hits	10
SwissProt Accessions	Q9R1J0, O55109	Gene names	Nsdhl
Domain Architecture
Description	Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating (EC 1.1.1.170).

GMDS_HUMAN
θ value	1.38499e-08 (rank : 11)	NC score	0.459898 (rank : 9)
Query Neighborhood Hits	19	Target Neighborhood Hits	13	Shared Neighborhood Hits	8
SwissProt Accessions	O60547, O75357, Q5T954, Q6FH09, Q9UGZ3, Q9UJK9	Gene names	GMDS
Domain Architecture
Description	GDP-mannose 4,6 dehydratase (EC 4.2.1.47) (GDP-D-mannose dehydratase) (GMD).

GMDS_MOUSE
θ value	1.99992e-07 (rank : 12)	NC score	0.449865 (rank : 10)
Query Neighborhood Hits	19	Target Neighborhood Hits	13	Shared Neighborhood Hits	8
SwissProt Accessions	Q8K0C9	Gene names	Gmds
Domain Architecture	No domain graphic available
Description	GDP-mannose 4,6 dehydratase (EC 4.2.1.47) (GDP-D-mannose dehydratase) (GMD).

HPS3_MOUSE
θ value	1.38821 (rank : 13)	NC score	0.046436 (rank : 24)
Query Neighborhood Hits	19	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	Q91VB4, Q8VDX2, Q8VHT1	Gene names	Hps3, Coa
Domain Architecture	No domain graphic available
Description	Hermansky-Pudlak syndrome 3 protein homolog (Cocoa protein).

CRSP6_HUMAN
θ value	1.81305 (rank : 14)	NC score	0.062812 (rank : 23)
Query Neighborhood Hits	19	Target Neighborhood Hits	18	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NVC6, Q9UNP7, Q9Y2W0, Q9Y660	Gene names	CRSP6, ARC77, DRIP77, DRIP80, TRAP80
Domain Architecture	No domain graphic available
Description	CRSP complex subunit 6 (Cofactor required for Sp1 transcriptional activation subunit 6) (Transcriptional coactivator CRSP77) (Vitamin D3 receptor-interacting protein complex 80 kDa component) (DRIP80) (Thyroid hormone receptor-associated protein complex 80 kDa component) (Trap80) (Activator-recruited cofactor 77 kDa component) (ARC77).

3BHS3_MOUSE
θ value	2.36792 (rank : 15)	NC score	0.117919 (rank : 14)
Query Neighborhood Hits	19	Target Neighborhood Hits	23	Shared Neighborhood Hits	10
SwissProt Accessions	P26150	Gene names	Hsd3b3
Domain Architecture	No domain graphic available
Description	3 beta-hydroxysteroid dehydrogenase/delta 5-->4-isomerase type III (3Beta-HSD III) [Includes: 3-beta-hydroxy-delta(5)-steroid dehydrogenase (EC 1.1.1.145) (3-beta-hydroxy-5-ene steroid dehydrogenase) (Progesterone reductase); Steroid delta-isomerase (EC 5.3.3.1) (Delta-5-3-ketosteroid isomerase)].

LRBA_HUMAN
θ value	2.36792 (rank : 16)	NC score	0.021372 (rank : 26)
Query Neighborhood Hits	19	Target Neighborhood Hits	196	Shared Neighborhood Hits	3
SwissProt Accessions	P50851, Q9H2U3, Q9H2U4	Gene names	LRBA, BGL, CDC4L, LBA
Domain Architecture
Description	Lipopolysaccharide-responsive and beige-like anchor protein (CDC4-like protein) (Beige-like protein).

CD19_HUMAN
θ value	4.03905 (rank : 17)	NC score	0.034612 (rank : 25)
Query Neighborhood Hits	19	Target Neighborhood Hits	63	Shared Neighborhood Hits	3
SwissProt Accessions	P15391, Q96S68, Q9BRD6	Gene names	CD19
Domain Architecture
Description	B-lymphocyte antigen CD19 precursor (Differentiation antigen CD19) (B- lymphocyte surface antigen B4) (Leu-12).

3BHS6_MOUSE
θ value	5.27518 (rank : 18)	NC score	0.113597 (rank : 16)
Query Neighborhood Hits	19	Target Neighborhood Hits	25	Shared Neighborhood Hits	10
SwissProt Accessions	O35469	Gene names	Hsd3b6
Domain Architecture
Description	3 beta-hydroxysteroid dehydrogenase/delta 5-->4-isomerase type VI (3Beta-HSD VI) [Includes: 3-beta-hydroxy-delta(5)-steroid dehydrogenase (EC 1.1.1.145) (3-beta-hydroxy-5-ene steroid dehydrogenase) (Progesterone reductase); Steroid delta-isomerase (EC 5.3.3.1) (Delta-5-3-ketosteroid isomerase)].

REG4_MOUSE
θ value	8.99809 (rank : 19)	NC score	0.012054 (rank : 27)
Query Neighborhood Hits	19	Target Neighborhood Hits	101	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D8G5, Q3TS25, Q9D858	Gene names	Reg4
Domain Architecture	No domain graphic available
Description	Regenerating islet-derived protein 4 precursor.

3BHS1_HUMAN
θ value	θ > 10 (rank : 20)	NC score	0.103868 (rank : 19)
Query Neighborhood Hits	19	Target Neighborhood Hits	19	Shared Neighborhood Hits	8
SwissProt Accessions	P14060, Q14545, Q8IV65	Gene names	HSD3B1, 3BH, HSDB3A
Domain Architecture
Description	3 beta-hydroxysteroid dehydrogenase/delta 5-->4-isomerase type I (3Beta-HSD I) (Trophoblast antigen FDO161G) [Includes: 3-beta-hydroxy- delta(5)-steroid dehydrogenase (EC 1.1.1.145) (3-beta-hydroxy-5-ene steroid dehydrogenase) (Progesterone reductase); Steroid delta- isomerase (EC 5.3.3.1) (Delta-5-3-ketosteroid isomerase)].

3BHS1_MOUSE
θ value	θ > 10 (rank : 21)	NC score	0.101735 (rank : 20)
Query Neighborhood Hits	19	Target Neighborhood Hits	21	Shared Neighborhood Hits	8
SwissProt Accessions	P24815, Q7TQ00	Gene names	Hsd3b1, Hsd3b
Domain Architecture
Description	3 beta-hydroxysteroid dehydrogenase/delta 5-->4-isomerase type I (3Beta-HSD I) [Includes: 3-beta-hydroxy-delta(5)-steroid dehydrogenase (EC 1.1.1.145) (3-beta-hydroxy-5-ene steroid dehydrogenase) (Progesterone reductase); Steroid delta-isomerase (EC 5.3.3.1) (Delta- 5-3-ketosteroid isomerase)].

3BHS2_HUMAN
θ value	θ > 10 (rank : 22)	NC score	0.104875 (rank : 17)
Query Neighborhood Hits	19	Target Neighborhood Hits	16	Shared Neighborhood Hits	8
SwissProt Accessions	P26439, Q16010, Q53GD4, Q6LDB9	Gene names	HSD3B2, HSDB3B
Domain Architecture
Description	3 beta-hydroxysteroid dehydrogenase/delta 5-->4-isomerase type II (3Beta-HSD II) [Includes: 3-beta-hydroxy-delta(5)-steroid dehydrogenase (EC 1.1.1.145) (3-beta-hydroxy-5-ene steroid dehydrogenase) (Progesterone reductase); Steroid delta-isomerase (EC 5.3.3.1) (Delta-5-3-ketosteroid isomerase)].

3BHS2_MOUSE
θ value	θ > 10 (rank : 23)	NC score	0.104149 (rank : 18)
Query Neighborhood Hits	19	Target Neighborhood Hits	20	Shared Neighborhood Hits	8
SwissProt Accessions	P26149, Q8R0J6	Gene names	Hsd3b2
Domain Architecture
Description	3 beta-hydroxysteroid dehydrogenase/delta 5-->4-isomerase type II (3Beta-HSD II) [Includes: 3-beta-hydroxy-delta(5)-steroid dehydrogenase (EC 1.1.1.145) (3-beta-hydroxy-5-ene steroid dehydrogenase) (Progesterone reductase); Steroid delta-isomerase (EC 5.3.3.1) (Delta-5-3-ketosteroid isomerase)].

3BHS4_MOUSE
θ value	θ > 10 (rank : 24)	NC score	0.098697 (rank : 22)
Query Neighborhood Hits	19	Target Neighborhood Hits	17	Shared Neighborhood Hits	8
SwissProt Accessions	Q61767	Gene names	Hsd3b4
Domain Architecture
Description	3 beta-hydroxysteroid dehydrogenase type 4 (3 beta-hydroxysteroid dehydrogenase type IV) (3Beta-HSD IV) (NADPH-dependent 3-beta-hydroxy- delta(5)-steroid dehydrogenase) (EC 1.1.1.-) (3-beta-hydroxy-5-ene steroid dehydrogenase) (Progesterone reductase).

3BHS5_MOUSE
θ value	θ > 10 (rank : 25)	NC score	0.100449 (rank : 21)
Query Neighborhood Hits	19	Target Neighborhood Hits	18	Shared Neighborhood Hits	8
SwissProt Accessions	Q61694, Q91X27	Gene names	Hsd3b5
Domain Architecture
Description	3 beta-hydroxysteroid dehydrogenase type 5 (3 beta-hydroxysteroid dehydrogenase type V) (3Beta-HSD V) (NADPH-dependent 3-beta-hydroxy- delta(5)-steroid dehydrogenase) (EC 1.1.1.-) (3-beta-hydroxy-5-ene steroid dehydrogenase) (Progesterone reductase).

3BHS7_HUMAN
θ value	θ > 10 (rank : 26)	NC score	0.117373 (rank : 15)
Query Neighborhood Hits	19	Target Neighborhood Hits	20	Shared Neighborhood Hits	8
SwissProt Accessions	Q9H2F3, Q9BSN9	Gene names	HSD3B7
Domain Architecture
Description	3 beta-hydroxysteroid dehydrogenase type 7 (3 beta-hydroxysteroid dehydrogenase type VII) (3Beta-HSD VII) (3-beta-hydroxy-delta(5)-C27 steroid oxidoreductase) (EC 1.1.1.-) (C(27) 3beta-HSD).

3BHS7_MOUSE
θ value	θ > 10 (rank : 27)	NC score	0.126257 (rank : 13)
Query Neighborhood Hits	19	Target Neighborhood Hits	21	Shared Neighborhood Hits	8
SwissProt Accessions	Q9EQC1	Gene names	Hsd3b7
Domain Architecture
Description	3 beta-hydroxysteroid dehydrogenase type 7 (3 beta-hydroxysteroid dehydrogenase type VII) (3Beta-HSD VII) (3-beta-hydroxy-delta(5)-C27 steroid oxidoreductase) (EC 1.1.1.-) (C(27) 3beta-HSD).

Hits sorted by NC score

UXS1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	19	Target Neighborhood Hits	19	Shared Neighborhood Hits	19
SwissProt Accessions	Q8NBZ7, Q8NBX3, Q9H5C2	Gene names	UXS1
Domain Architecture	No domain graphic available
Description	UDP-glucuronic acid decarboxylase 1 (EC 4.1.1.35) (UDP-glucuronate decarboxylase 1) (UGD) (UXS-1).

UXS1_MOUSE
NC score	0.999958 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	19	Target Neighborhood Hits	19	Shared Neighborhood Hits	19
SwissProt Accessions	Q91XL3, Q3U854	Gene names	Uxs1
Domain Architecture	No domain graphic available
Description	UDP-glucuronic acid decarboxylase 1 (EC 4.1.1.35) (UDP-glucuronate decarboxylase 1) (UGD) (UXS-1).

TGDS_MOUSE
NC score	0.717765 (rank : 3)	θ value	2.77775e-25 (rank : 3)
Query Neighborhood Hits	19	Target Neighborhood Hits	26	Shared Neighborhood Hits	14
SwissProt Accessions	Q8VDR7	Gene names	Tgds
Domain Architecture
Description	dTDP-D-glucose 4,6-dehydratase (EC 4.2.1.46).

TGDS_HUMAN
NC score	0.710963 (rank : 4)	θ value	1.5242e-23 (rank : 4)
Query Neighborhood Hits	19	Target Neighborhood Hits	23	Shared Neighborhood Hits	14
SwissProt Accessions	O95455, Q5T3Z2, Q9H1T9	Gene names	TGDS
Domain Architecture
Description	dTDP-D-glucose 4,6-dehydratase (EC 4.2.1.46).

GALE_MOUSE
NC score	0.605868 (rank : 5)	θ value	2.43908e-13 (rank : 6)
Query Neighborhood Hits	19	Target Neighborhood Hits	28	Shared Neighborhood Hits	14
SwissProt Accessions	Q8R059	Gene names	Gale
Domain Architecture
Description	UDP-glucose 4-epimerase (EC 5.1.3.2) (Galactowaldenase) (UDP-galactose 4-epimerase).

GALE_HUMAN
NC score	0.604834 (rank : 6)	θ value	1.86753e-13 (rank : 5)
Query Neighborhood Hits	19	Target Neighborhood Hits	25	Shared Neighborhood Hits	14
SwissProt Accessions	Q14376, Q86W41, Q9BVE3, Q9UJB4	Gene names	GALE
Domain Architecture
Description	UDP-glucose 4-epimerase (EC 5.1.3.2) (Galactowaldenase) (UDP-galactose 4-epimerase).

FCL_HUMAN
NC score	0.548135 (rank : 7)	θ value	7.09661e-13 (rank : 7)
Query Neighborhood Hits	19	Target Neighborhood Hits	11	Shared Neighborhood Hits	8
SwissProt Accessions	Q13630, Q567Q9, Q9UDG7	Gene names	TSTA3
Domain Architecture
Description	GDP-L-fucose synthetase (EC 1.1.1.271) (Protein FX) (Red cell NADP(H)- binding protein) (GDP-4-keto-6-deoxy-D-mannose-3,5-epimerase-4- reductase).

FCL_MOUSE
NC score	0.528097 (rank : 8)	θ value	2.28291e-11 (rank : 9)
Query Neighborhood Hits	19	Target Neighborhood Hits	10	Shared Neighborhood Hits	8
SwissProt Accessions	P23591	Gene names	Tsta3, P35b, Tstap35b
Domain Architecture
Description	GDP-L-fucose synthetase (EC 1.1.1.271) (Protein FX) (Red cell NADP(H)- binding protein) (GDP-4-keto-6-deoxy-D-mannose-3,5-epimerase-4- reductase) (Transplantation antigen P35B) (Tum-P35B antigen).

GMDS_HUMAN
NC score	0.459898 (rank : 9)	θ value	1.38499e-08 (rank : 11)
Query Neighborhood Hits	19	Target Neighborhood Hits	13	Shared Neighborhood Hits	8
SwissProt Accessions	O60547, O75357, Q5T954, Q6FH09, Q9UGZ3, Q9UJK9	Gene names	GMDS
Domain Architecture
Description	GDP-mannose 4,6 dehydratase (EC 4.2.1.47) (GDP-D-mannose dehydratase) (GMD).

GMDS_MOUSE
NC score	0.449865 (rank : 10)	θ value	1.99992e-07 (rank : 12)
Query Neighborhood Hits	19	Target Neighborhood Hits	13	Shared Neighborhood Hits	8
SwissProt Accessions	Q8K0C9	Gene names	Gmds
Domain Architecture	No domain graphic available
Description	GDP-mannose 4,6 dehydratase (EC 4.2.1.47) (GDP-D-mannose dehydratase) (GMD).

NSDHL_MOUSE
NC score	0.399929 (rank : 11)	θ value	2.28291e-11 (rank : 10)
Query Neighborhood Hits	19	Target Neighborhood Hits	25	Shared Neighborhood Hits	10
SwissProt Accessions	Q9R1J0, O55109	Gene names	Nsdhl
Domain Architecture
Description	Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating (EC 1.1.1.170).

NSDHL_HUMAN
NC score	0.398869 (rank : 12)	θ value	3.52202e-12 (rank : 8)
Query Neighborhood Hits	19	Target Neighborhood Hits	27	Shared Neighborhood Hits	10
SwissProt Accessions	Q15738, O00344	Gene names	NSDHL, H105E3
Domain Architecture
Description	Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating (EC 1.1.1.170) (H105e3 protein).

3BHS7_MOUSE
NC score	0.126257 (rank : 13)	θ value	θ > 10 (rank : 27)
Query Neighborhood Hits	19	Target Neighborhood Hits	21	Shared Neighborhood Hits	8
SwissProt Accessions	Q9EQC1	Gene names	Hsd3b7
Domain Architecture
Description	3 beta-hydroxysteroid dehydrogenase type 7 (3 beta-hydroxysteroid dehydrogenase type VII) (3Beta-HSD VII) (3-beta-hydroxy-delta(5)-C27 steroid oxidoreductase) (EC 1.1.1.-) (C(27) 3beta-HSD).

3BHS3_MOUSE
NC score	0.117919 (rank : 14)	θ value	2.36792 (rank : 15)
Query Neighborhood Hits	19	Target Neighborhood Hits	23	Shared Neighborhood Hits	10
SwissProt Accessions	P26150	Gene names	Hsd3b3
Domain Architecture	No domain graphic available
Description	3 beta-hydroxysteroid dehydrogenase/delta 5-->4-isomerase type III (3Beta-HSD III) [Includes: 3-beta-hydroxy-delta(5)-steroid dehydrogenase (EC 1.1.1.145) (3-beta-hydroxy-5-ene steroid dehydrogenase) (Progesterone reductase); Steroid delta-isomerase (EC 5.3.3.1) (Delta-5-3-ketosteroid isomerase)].

3BHS7_HUMAN
NC score	0.117373 (rank : 15)	θ value	θ > 10 (rank : 26)
Query Neighborhood Hits	19	Target Neighborhood Hits	20	Shared Neighborhood Hits	8
SwissProt Accessions	Q9H2F3, Q9BSN9	Gene names	HSD3B7
Domain Architecture
Description	3 beta-hydroxysteroid dehydrogenase type 7 (3 beta-hydroxysteroid dehydrogenase type VII) (3Beta-HSD VII) (3-beta-hydroxy-delta(5)-C27 steroid oxidoreductase) (EC 1.1.1.-) (C(27) 3beta-HSD).

3BHS6_MOUSE
NC score	0.113597 (rank : 16)	θ value	5.27518 (rank : 18)
Query Neighborhood Hits	19	Target Neighborhood Hits	25	Shared Neighborhood Hits	10
SwissProt Accessions	O35469	Gene names	Hsd3b6
Domain Architecture
Description	3 beta-hydroxysteroid dehydrogenase/delta 5-->4-isomerase type VI (3Beta-HSD VI) [Includes: 3-beta-hydroxy-delta(5)-steroid dehydrogenase (EC 1.1.1.145) (3-beta-hydroxy-5-ene steroid dehydrogenase) (Progesterone reductase); Steroid delta-isomerase (EC 5.3.3.1) (Delta-5-3-ketosteroid isomerase)].

3BHS2_HUMAN
NC score	0.104875 (rank : 17)	θ value	θ > 10 (rank : 22)
Query Neighborhood Hits	19	Target Neighborhood Hits	16	Shared Neighborhood Hits	8
SwissProt Accessions	P26439, Q16010, Q53GD4, Q6LDB9	Gene names	HSD3B2, HSDB3B
Domain Architecture
Description	3 beta-hydroxysteroid dehydrogenase/delta 5-->4-isomerase type II (3Beta-HSD II) [Includes: 3-beta-hydroxy-delta(5)-steroid dehydrogenase (EC 1.1.1.145) (3-beta-hydroxy-5-ene steroid dehydrogenase) (Progesterone reductase); Steroid delta-isomerase (EC 5.3.3.1) (Delta-5-3-ketosteroid isomerase)].

3BHS2_MOUSE
NC score	0.104149 (rank : 18)	θ value	θ > 10 (rank : 23)
Query Neighborhood Hits	19	Target Neighborhood Hits	20	Shared Neighborhood Hits	8
SwissProt Accessions	P26149, Q8R0J6	Gene names	Hsd3b2
Domain Architecture
Description	3 beta-hydroxysteroid dehydrogenase/delta 5-->4-isomerase type II (3Beta-HSD II) [Includes: 3-beta-hydroxy-delta(5)-steroid dehydrogenase (EC 1.1.1.145) (3-beta-hydroxy-5-ene steroid dehydrogenase) (Progesterone reductase); Steroid delta-isomerase (EC 5.3.3.1) (Delta-5-3-ketosteroid isomerase)].

3BHS1_HUMAN
NC score	0.103868 (rank : 19)	θ value	θ > 10 (rank : 20)
Query Neighborhood Hits	19	Target Neighborhood Hits	19	Shared Neighborhood Hits	8
SwissProt Accessions	P14060, Q14545, Q8IV65	Gene names	HSD3B1, 3BH, HSDB3A
Domain Architecture
Description	3 beta-hydroxysteroid dehydrogenase/delta 5-->4-isomerase type I (3Beta-HSD I) (Trophoblast antigen FDO161G) [Includes: 3-beta-hydroxy- delta(5)-steroid dehydrogenase (EC 1.1.1.145) (3-beta-hydroxy-5-ene steroid dehydrogenase) (Progesterone reductase); Steroid delta- isomerase (EC 5.3.3.1) (Delta-5-3-ketosteroid isomerase)].

3BHS1_MOUSE
NC score	0.101735 (rank : 20)	θ value	θ > 10 (rank : 21)
Query Neighborhood Hits	19	Target Neighborhood Hits	21	Shared Neighborhood Hits	8
SwissProt Accessions	P24815, Q7TQ00	Gene names	Hsd3b1, Hsd3b
Domain Architecture
Description	3 beta-hydroxysteroid dehydrogenase/delta 5-->4-isomerase type I (3Beta-HSD I) [Includes: 3-beta-hydroxy-delta(5)-steroid dehydrogenase (EC 1.1.1.145) (3-beta-hydroxy-5-ene steroid dehydrogenase) (Progesterone reductase); Steroid delta-isomerase (EC 5.3.3.1) (Delta- 5-3-ketosteroid isomerase)].

3BHS5_MOUSE
NC score	0.100449 (rank : 21)	θ value	θ > 10 (rank : 25)
Query Neighborhood Hits	19	Target Neighborhood Hits	18	Shared Neighborhood Hits	8
SwissProt Accessions	Q61694, Q91X27	Gene names	Hsd3b5
Domain Architecture
Description	3 beta-hydroxysteroid dehydrogenase type 5 (3 beta-hydroxysteroid dehydrogenase type V) (3Beta-HSD V) (NADPH-dependent 3-beta-hydroxy- delta(5)-steroid dehydrogenase) (EC 1.1.1.-) (3-beta-hydroxy-5-ene steroid dehydrogenase) (Progesterone reductase).

3BHS4_MOUSE
NC score	0.098697 (rank : 22)	θ value	θ > 10 (rank : 24)
Query Neighborhood Hits	19	Target Neighborhood Hits	17	Shared Neighborhood Hits	8
SwissProt Accessions	Q61767	Gene names	Hsd3b4
Domain Architecture
Description	3 beta-hydroxysteroid dehydrogenase type 4 (3 beta-hydroxysteroid dehydrogenase type IV) (3Beta-HSD IV) (NADPH-dependent 3-beta-hydroxy- delta(5)-steroid dehydrogenase) (EC 1.1.1.-) (3-beta-hydroxy-5-ene steroid dehydrogenase) (Progesterone reductase).

CRSP6_HUMAN
NC score	0.062812 (rank : 23)	θ value	1.81305 (rank : 14)
Query Neighborhood Hits	19	Target Neighborhood Hits	18	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NVC6, Q9UNP7, Q9Y2W0, Q9Y660	Gene names	CRSP6, ARC77, DRIP77, DRIP80, TRAP80
Domain Architecture	No domain graphic available
Description	CRSP complex subunit 6 (Cofactor required for Sp1 transcriptional activation subunit 6) (Transcriptional coactivator CRSP77) (Vitamin D3 receptor-interacting protein complex 80 kDa component) (DRIP80) (Thyroid hormone receptor-associated protein complex 80 kDa component) (Trap80) (Activator-recruited cofactor 77 kDa component) (ARC77).

HPS3_MOUSE
NC score	0.046436 (rank : 24)	θ value	1.38821 (rank : 13)
Query Neighborhood Hits	19	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	Q91VB4, Q8VDX2, Q8VHT1	Gene names	Hps3, Coa
Domain Architecture	No domain graphic available
Description	Hermansky-Pudlak syndrome 3 protein homolog (Cocoa protein).

CD19_HUMAN
NC score	0.034612 (rank : 25)	θ value	4.03905 (rank : 17)
Query Neighborhood Hits	19	Target Neighborhood Hits	63	Shared Neighborhood Hits	3
SwissProt Accessions	P15391, Q96S68, Q9BRD6	Gene names	CD19
Domain Architecture
Description	B-lymphocyte antigen CD19 precursor (Differentiation antigen CD19) (B- lymphocyte surface antigen B4) (Leu-12).

LRBA_HUMAN
NC score	0.021372 (rank : 26)	θ value	2.36792 (rank : 16)
Query Neighborhood Hits	19	Target Neighborhood Hits	196	Shared Neighborhood Hits	3
SwissProt Accessions	P50851, Q9H2U3, Q9H2U4	Gene names	LRBA, BGL, CDC4L, LBA
Domain Architecture
Description	Lipopolysaccharide-responsive and beige-like anchor protein (CDC4-like protein) (Beige-like protein).

REG4_MOUSE
NC score	0.012054 (rank : 27)	θ value	8.99809 (rank : 19)
Query Neighborhood Hits	19	Target Neighborhood Hits	101	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D8G5, Q3TS25, Q9D858	Gene names	Reg4
Domain Architecture	No domain graphic available
Description	Regenerating islet-derived protein 4 precursor.