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Network neighborhood for query Sequence : NSDHL_HUMAN

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NSDHL_HUMAN
 
SwissProt Accessions Q15738, O00344 Gene names NSDHL, H105E3
Domain
Architecture
Description Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating (EC 1.1.1.170) (H105e3 protein).
Rank Plots


Hits sorted by θ


NSDHL_HUMAN
 
θ value 0 (rank : 1) NC score 0.999962 (rank : 1)
Query Neighborhood Hits 27 Target Neighborhood Hits 27 Shared Neighborhood Hits 27
SwissProt Accessions Q15738, O00344 Gene names NSDHL, H105E3
Domain
Architecture
Description Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating (EC 1.1.1.170) (H105e3 protein).
NSDHL_MOUSE
 
θ value 1.61255e-174 (rank : 2) NC score 0.997012 (rank : 2)
Query Neighborhood Hits 27 Target Neighborhood Hits 25 Shared Neighborhood Hits 21
SwissProt Accessions Q9R1J0, O55109 Gene names Nsdhl
Domain
Architecture
Description Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating (EC 1.1.1.170).
3BHS7_MOUSE
 
θ value 3.87602e-27 (rank : 3) NC score 0.838451 (rank : 3)
Query Neighborhood Hits 27 Target Neighborhood Hits 21 Shared Neighborhood Hits 17
SwissProt Accessions Q9EQC1 Gene names Hsd3b7
Domain
Architecture
Description 3 beta-hydroxysteroid dehydrogenase type 7 (3 beta-hydroxysteroid dehydrogenase type VII) (3Beta-HSD VII) (3-beta-hydroxy-delta(5)-C27 steroid oxidoreductase) (EC 1.1.1.-) (C(27) 3beta-HSD).
3BHS6_MOUSE
 
θ value 5.06226e-27 (rank : 4) NC score 0.808017 (rank : 6)
Query Neighborhood Hits 27 Target Neighborhood Hits 25 Shared Neighborhood Hits 18
SwissProt Accessions O35469 Gene names Hsd3b6
Domain
Architecture
Description 3 beta-hydroxysteroid dehydrogenase/delta 5-->4-isomerase type VI (3Beta-HSD VI) [Includes: 3-beta-hydroxy-delta(5)-steroid dehydrogenase (EC 1.1.1.145) (3-beta-hydroxy-5-ene steroid dehydrogenase) (Progesterone reductase); Steroid delta-isomerase (EC 5.3.3.1) (Delta-5-3-ketosteroid isomerase)].
3BHS3_MOUSE
 
θ value 6.61148e-27 (rank : 5) NC score 0.808824 (rank : 5)
Query Neighborhood Hits 27 Target Neighborhood Hits 23 Shared Neighborhood Hits 19
SwissProt Accessions P26150 Gene names Hsd3b3
Domain
Architecture

No domain graphic available

Description 3 beta-hydroxysteroid dehydrogenase/delta 5-->4-isomerase type III (3Beta-HSD III) [Includes: 3-beta-hydroxy-delta(5)-steroid dehydrogenase (EC 1.1.1.145) (3-beta-hydroxy-5-ene steroid dehydrogenase) (Progesterone reductase); Steroid delta-isomerase (EC 5.3.3.1) (Delta-5-3-ketosteroid isomerase)].
3BHS2_MOUSE
 
θ value 2.51237e-26 (rank : 6) NC score 0.805198 (rank : 7)
Query Neighborhood Hits 27 Target Neighborhood Hits 20 Shared Neighborhood Hits 16
SwissProt Accessions P26149, Q8R0J6 Gene names Hsd3b2
Domain
Architecture
Description 3 beta-hydroxysteroid dehydrogenase/delta 5-->4-isomerase type II (3Beta-HSD II) [Includes: 3-beta-hydroxy-delta(5)-steroid dehydrogenase (EC 1.1.1.145) (3-beta-hydroxy-5-ene steroid dehydrogenase) (Progesterone reductase); Steroid delta-isomerase (EC 5.3.3.1) (Delta-5-3-ketosteroid isomerase)].
3BHS7_HUMAN
 
θ value 2.12685e-25 (rank : 7) NC score 0.832362 (rank : 4)
Query Neighborhood Hits 27 Target Neighborhood Hits 20 Shared Neighborhood Hits 17
SwissProt Accessions Q9H2F3, Q9BSN9 Gene names HSD3B7
Domain
Architecture
Description 3 beta-hydroxysteroid dehydrogenase type 7 (3 beta-hydroxysteroid dehydrogenase type VII) (3Beta-HSD VII) (3-beta-hydroxy-delta(5)-C27 steroid oxidoreductase) (EC 1.1.1.-) (C(27) 3beta-HSD).
3BHS1_MOUSE
 
θ value 6.84181e-24 (rank : 8) NC score 0.795951 (rank : 10)
Query Neighborhood Hits 27 Target Neighborhood Hits 21 Shared Neighborhood Hits 16
SwissProt Accessions P24815, Q7TQ00 Gene names Hsd3b1, Hsd3b
Domain
Architecture
Description 3 beta-hydroxysteroid dehydrogenase/delta 5-->4-isomerase type I (3Beta-HSD I) [Includes: 3-beta-hydroxy-delta(5)-steroid dehydrogenase (EC 1.1.1.145) (3-beta-hydroxy-5-ene steroid dehydrogenase) (Progesterone reductase); Steroid delta-isomerase (EC 5.3.3.1) (Delta- 5-3-ketosteroid isomerase)].
3BHS2_HUMAN
 
θ value 3.39556e-23 (rank : 9) NC score 0.799984 (rank : 8)
Query Neighborhood Hits 27 Target Neighborhood Hits 16 Shared Neighborhood Hits 16
SwissProt Accessions P26439, Q16010, Q53GD4, Q6LDB9 Gene names HSD3B2, HSDB3B
Domain
Architecture
Description 3 beta-hydroxysteroid dehydrogenase/delta 5-->4-isomerase type II (3Beta-HSD II) [Includes: 3-beta-hydroxy-delta(5)-steroid dehydrogenase (EC 1.1.1.145) (3-beta-hydroxy-5-ene steroid dehydrogenase) (Progesterone reductase); Steroid delta-isomerase (EC 5.3.3.1) (Delta-5-3-ketosteroid isomerase)].
3BHS1_HUMAN
 
θ value 1.6852e-22 (rank : 10) NC score 0.797345 (rank : 9)
Query Neighborhood Hits 27 Target Neighborhood Hits 19 Shared Neighborhood Hits 16
SwissProt Accessions P14060, Q14545, Q8IV65 Gene names HSD3B1, 3BH, HSDB3A
Domain
Architecture
Description 3 beta-hydroxysteroid dehydrogenase/delta 5-->4-isomerase type I (3Beta-HSD I) (Trophoblast antigen FDO161G) [Includes: 3-beta-hydroxy- delta(5)-steroid dehydrogenase (EC 1.1.1.145) (3-beta-hydroxy-5-ene steroid dehydrogenase) (Progesterone reductase); Steroid delta- isomerase (EC 5.3.3.1) (Delta-5-3-ketosteroid isomerase)].
3BHS5_MOUSE
 
θ value 1.74391e-19 (rank : 11) NC score 0.789096 (rank : 11)
Query Neighborhood Hits 27 Target Neighborhood Hits 18 Shared Neighborhood Hits 16
SwissProt Accessions Q61694, Q91X27 Gene names Hsd3b5
Domain
Architecture
Description 3 beta-hydroxysteroid dehydrogenase type 5 (3 beta-hydroxysteroid dehydrogenase type V) (3Beta-HSD V) (NADPH-dependent 3-beta-hydroxy- delta(5)-steroid dehydrogenase) (EC 1.1.1.-) (3-beta-hydroxy-5-ene steroid dehydrogenase) (Progesterone reductase).
3BHS4_MOUSE
 
θ value 1.24977e-17 (rank : 12) NC score 0.780677 (rank : 12)
Query Neighborhood Hits 27 Target Neighborhood Hits 17 Shared Neighborhood Hits 16
SwissProt Accessions Q61767 Gene names Hsd3b4
Domain
Architecture
Description 3 beta-hydroxysteroid dehydrogenase type 4 (3 beta-hydroxysteroid dehydrogenase type IV) (3Beta-HSD IV) (NADPH-dependent 3-beta-hydroxy- delta(5)-steroid dehydrogenase) (EC 1.1.1.-) (3-beta-hydroxy-5-ene steroid dehydrogenase) (Progesterone reductase).
UXS1_MOUSE
 
θ value 2.69671e-12 (rank : 13) NC score 0.399742 (rank : 17)
Query Neighborhood Hits 27 Target Neighborhood Hits 19 Shared Neighborhood Hits 10
SwissProt Accessions Q91XL3, Q3U854 Gene names Uxs1
Domain
Architecture

No domain graphic available

Description UDP-glucuronic acid decarboxylase 1 (EC 4.1.1.35) (UDP-glucuronate decarboxylase 1) (UGD) (UXS-1).
UXS1_HUMAN
 
θ value 3.52202e-12 (rank : 14) NC score 0.398869 (rank : 18)
Query Neighborhood Hits 27 Target Neighborhood Hits 19 Shared Neighborhood Hits 10
SwissProt Accessions Q8NBZ7, Q8NBX3, Q9H5C2 Gene names UXS1
Domain
Architecture

No domain graphic available

Description UDP-glucuronic acid decarboxylase 1 (EC 4.1.1.35) (UDP-glucuronate decarboxylase 1) (UGD) (UXS-1).
TGDS_HUMAN
 
θ value 4.92598e-06 (rank : 15) NC score 0.519026 (rank : 13)
Query Neighborhood Hits 27 Target Neighborhood Hits 23 Shared Neighborhood Hits 18
SwissProt Accessions O95455, Q5T3Z2, Q9H1T9 Gene names TGDS
Domain
Architecture
Description dTDP-D-glucose 4,6-dehydratase (EC 4.2.1.46).
TGDS_MOUSE
 
θ value 4.92598e-06 (rank : 16) NC score 0.518808 (rank : 14)
Query Neighborhood Hits 27 Target Neighborhood Hits 26 Shared Neighborhood Hits 20
SwissProt Accessions Q8VDR7 Gene names Tgds
Domain
Architecture
Description dTDP-D-glucose 4,6-dehydratase (EC 4.2.1.46).
GALE_HUMAN
 
θ value 0.000158464 (rank : 17) NC score 0.441911 (rank : 15)
Query Neighborhood Hits 27 Target Neighborhood Hits 25 Shared Neighborhood Hits 18
SwissProt Accessions Q14376, Q86W41, Q9BVE3, Q9UJB4 Gene names GALE
Domain
Architecture
Description UDP-glucose 4-epimerase (EC 5.1.3.2) (Galactowaldenase) (UDP-galactose 4-epimerase).
GALE_MOUSE
 
θ value 0.00134147 (rank : 18) NC score 0.405262 (rank : 16)
Query Neighborhood Hits 27 Target Neighborhood Hits 28 Shared Neighborhood Hits 18
SwissProt Accessions Q8R059 Gene names Gale
Domain
Architecture
Description UDP-glucose 4-epimerase (EC 5.1.3.2) (Galactowaldenase) (UDP-galactose 4-epimerase).
NDUA9_MOUSE
 
θ value 0.365318 (rank : 19) NC score 0.086093 (rank : 23)
Query Neighborhood Hits 27 Target Neighborhood Hits 6 Shared Neighborhood Hits 6
SwissProt Accessions Q9DC69, Q99JP9 Gene names Ndufa9
Domain
Architecture
Description NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial precursor (EC 1.6.5.3) (EC 1.6.99.3) (NADH-ubiquinone oxidoreductase 39 kDa subunit) (Complex I-39kD) (CI-39kD).
BLVRB_MOUSE
 
θ value 0.62314 (rank : 20) NC score 0.061545 (rank : 25)
Query Neighborhood Hits 27 Target Neighborhood Hits 10 Shared Neighborhood Hits 4
SwissProt Accessions Q923D2 Gene names Blvrb
Domain
Architecture

No domain graphic available

Description Flavin reductase (EC 1.5.1.30) (FR) (NADPH-dependent diaphorase) (NADPH-flavin reductase) (FLR) (Biliverdin reductase B) (EC 1.3.1.24) (BVR-B) (Biliverdin-IX beta-reductase).
NDUA9_HUMAN
 
θ value 1.38821 (rank : 21) NC score 0.066971 (rank : 24)
Query Neighborhood Hits 27 Target Neighborhood Hits 9 Shared Neighborhood Hits 5
SwissProt Accessions Q16795, Q14076, Q2NKX0 Gene names NDUFA9, NDUFS2L
Domain
Architecture
Description NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial precursor (EC 1.6.5.3) (EC 1.6.99.3) (NADH-ubiquinone oxidoreductase 39 kDa subunit) (Complex I-39kD) (CI-39kD).
IL16_MOUSE
 
θ value 1.81305 (rank : 22) NC score 0.016680 (rank : 27)
Query Neighborhood Hits 27 Target Neighborhood Hits 189 Shared Neighborhood Hits 2
SwissProt Accessions O54824, O70236, Q3TEM4, Q8R0G5 Gene names Il16
Domain
Architecture

No domain graphic available

Description Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).
AK1C1_HUMAN
 
θ value 6.88961 (rank : 23) NC score 0.011075 (rank : 30)
Query Neighborhood Hits 27 Target Neighborhood Hits 29 Shared Neighborhood Hits 4
SwissProt Accessions Q04828, P52896, Q5SR15, Q9UCX2 Gene names AKR1C1, DDH, DDH1
Domain
Architecture
Description Aldo-keto reductase family 1 member C1 (EC 1.1.1.-) (20-alpha- hydroxysteroid dehydrogenase) (EC 1.1.1.149) (20-alpha-HSD) (Trans- 1,2-dihydrobenzene-1,2-diol dehydrogenase) (EC 1.3.1.20) (High- affinity hepatic bile acid-binding protein) (HBAB) (Chlordecone reductase homolog HAKRC) (Dihydrodiol dehydrogenase 1/2) (DD1/DD2).
AK1C4_HUMAN
 
θ value 6.88961 (rank : 24) NC score 0.011155 (rank : 29)
Query Neighborhood Hits 27 Target Neighborhood Hits 28 Shared Neighborhood Hits 4
SwissProt Accessions P17516, Q5T6A3, Q8WW84, Q9NS54 Gene names AKR1C4, CHDR
Domain
Architecture
Description Aldo-keto reductase family 1 member C4 (EC 1.1.1.-) (Chlordecone reductase) (EC 1.1.1.225) (CDR) (3-alpha-hydroxysteroid dehydrogenase type I) (EC 1.1.1.50) (3-alpha-HSD1) (Dihydrodiol dehydrogenase 4) (DD4) (HAKRA).
AK1D1_HUMAN
 
θ value 6.88961 (rank : 25) NC score 0.011205 (rank : 28)
Query Neighborhood Hits 27 Target Neighborhood Hits 29 Shared Neighborhood Hits 4
SwissProt Accessions P51857 Gene names AKR1D1, SRD5B1
Domain
Architecture
Description 3-oxo-5-beta-steroid 4-dehydrogenase (EC 1.3.1.3) (Delta(4)-3- ketosteroid 5-beta-reductase) (Aldo-keto reductase family 1 member D1).
AT12A_HUMAN
 
θ value 8.99809 (rank : 26) NC score 0.002992 (rank : 31)
Query Neighborhood Hits 27 Target Neighborhood Hits 65 Shared Neighborhood Hits 2
SwissProt Accessions P54707, Q13816, Q13817, Q16734 Gene names ATP12A, ATP1AL1
Domain
Architecture
Description Potassium-transporting ATPase alpha chain 2 (EC 3.6.3.10) (Proton pump) (Non-gastric H(+)/K(+) ATPase subunit alpha).
CRYL1_HUMAN
 
θ value 8.99809 (rank : 27) NC score 0.016794 (rank : 26)
Query Neighborhood Hits 27 Target Neighborhood Hits 12 Shared Neighborhood Hits 3
SwissProt Accessions Q9Y2S2, Q7Z4Z9 Gene names CRYL1, CRY
Domain
Architecture
Description Lambda-crystallin homolog.
FCL_HUMAN
 
θ value θ > 10 (rank : 28) NC score 0.097177 (rank : 19)
Query Neighborhood Hits 27 Target Neighborhood Hits 11 Shared Neighborhood Hits 6
SwissProt Accessions Q13630, Q567Q9, Q9UDG7 Gene names TSTA3
Domain
Architecture
Description GDP-L-fucose synthetase (EC 1.1.1.271) (Protein FX) (Red cell NADP(H)- binding protein) (GDP-4-keto-6-deoxy-D-mannose-3,5-epimerase-4- reductase).
FCL_MOUSE
 
θ value θ > 10 (rank : 29) NC score 0.090483 (rank : 20)
Query Neighborhood Hits 27 Target Neighborhood Hits 10 Shared Neighborhood Hits 6
SwissProt Accessions P23591 Gene names Tsta3, P35b, Tstap35b
Domain
Architecture
Description GDP-L-fucose synthetase (EC 1.1.1.271) (Protein FX) (Red cell NADP(H)- binding protein) (GDP-4-keto-6-deoxy-D-mannose-3,5-epimerase-4- reductase) (Transplantation antigen P35B) (Tum-P35B antigen).
GMDS_HUMAN
 
θ value θ > 10 (rank : 30) NC score 0.090453 (rank : 21)
Query Neighborhood Hits 27 Target Neighborhood Hits 13 Shared Neighborhood Hits 6
SwissProt Accessions O60547, O75357, Q5T954, Q6FH09, Q9UGZ3, Q9UJK9 Gene names GMDS
Domain
Architecture
Description GDP-mannose 4,6 dehydratase (EC 4.2.1.47) (GDP-D-mannose dehydratase) (GMD).
GMDS_MOUSE
 
θ value θ > 10 (rank : 31) NC score 0.088965 (rank : 22)
Query Neighborhood Hits 27 Target Neighborhood Hits 13 Shared Neighborhood Hits 6
SwissProt Accessions Q8K0C9 Gene names Gmds
Domain
Architecture

No domain graphic available

Description GDP-mannose 4,6 dehydratase (EC 4.2.1.47) (GDP-D-mannose dehydratase) (GMD).

Hits sorted by NC score


NSDHL_HUMAN
 
NC score 0.999962 (rank : 1) θ value 0 (rank : 1)
Query Neighborhood Hits 27 Target Neighborhood Hits 27 Shared Neighborhood Hits 27
SwissProt Accessions Q15738, O00344 Gene names NSDHL, H105E3
Domain
Architecture
Description Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating (EC 1.1.1.170) (H105e3 protein).
NSDHL_MOUSE
 
NC score 0.997012 (rank : 2) θ value 1.61255e-174 (rank : 2)
Query Neighborhood Hits 27 Target Neighborhood Hits 25 Shared Neighborhood Hits 21
SwissProt Accessions Q9R1J0, O55109 Gene names Nsdhl
Domain
Architecture
Description Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating (EC 1.1.1.170).
3BHS7_MOUSE
 
NC score 0.838451 (rank : 3) θ value 3.87602e-27 (rank : 3)
Query Neighborhood Hits 27 Target Neighborhood Hits 21 Shared Neighborhood Hits 17
SwissProt Accessions Q9EQC1 Gene names Hsd3b7
Domain
Architecture
Description 3 beta-hydroxysteroid dehydrogenase type 7 (3 beta-hydroxysteroid dehydrogenase type VII) (3Beta-HSD VII) (3-beta-hydroxy-delta(5)-C27 steroid oxidoreductase) (EC 1.1.1.-) (C(27) 3beta-HSD).
3BHS7_HUMAN
 
NC score 0.832362 (rank : 4) θ value 2.12685e-25 (rank : 7)
Query Neighborhood Hits 27 Target Neighborhood Hits 20 Shared Neighborhood Hits 17
SwissProt Accessions Q9H2F3, Q9BSN9 Gene names HSD3B7
Domain
Architecture
Description 3 beta-hydroxysteroid dehydrogenase type 7 (3 beta-hydroxysteroid dehydrogenase type VII) (3Beta-HSD VII) (3-beta-hydroxy-delta(5)-C27 steroid oxidoreductase) (EC 1.1.1.-) (C(27) 3beta-HSD).
3BHS3_MOUSE
 
NC score 0.808824 (rank : 5) θ value 6.61148e-27 (rank : 5)
Query Neighborhood Hits 27 Target Neighborhood Hits 23 Shared Neighborhood Hits 19
SwissProt Accessions P26150 Gene names Hsd3b3
Domain
Architecture

No domain graphic available

Description 3 beta-hydroxysteroid dehydrogenase/delta 5-->4-isomerase type III (3Beta-HSD III) [Includes: 3-beta-hydroxy-delta(5)-steroid dehydrogenase (EC 1.1.1.145) (3-beta-hydroxy-5-ene steroid dehydrogenase) (Progesterone reductase); Steroid delta-isomerase (EC 5.3.3.1) (Delta-5-3-ketosteroid isomerase)].
3BHS6_MOUSE
 
NC score 0.808017 (rank : 6) θ value 5.06226e-27 (rank : 4)
Query Neighborhood Hits 27 Target Neighborhood Hits 25 Shared Neighborhood Hits 18
SwissProt Accessions O35469 Gene names Hsd3b6
Domain
Architecture
Description 3 beta-hydroxysteroid dehydrogenase/delta 5-->4-isomerase type VI (3Beta-HSD VI) [Includes: 3-beta-hydroxy-delta(5)-steroid dehydrogenase (EC 1.1.1.145) (3-beta-hydroxy-5-ene steroid dehydrogenase) (Progesterone reductase); Steroid delta-isomerase (EC 5.3.3.1) (Delta-5-3-ketosteroid isomerase)].
3BHS2_MOUSE
 
NC score 0.805198 (rank : 7) θ value 2.51237e-26 (rank : 6)
Query Neighborhood Hits 27 Target Neighborhood Hits 20 Shared Neighborhood Hits 16
SwissProt Accessions P26149, Q8R0J6 Gene names Hsd3b2
Domain
Architecture
Description 3 beta-hydroxysteroid dehydrogenase/delta 5-->4-isomerase type II (3Beta-HSD II) [Includes: 3-beta-hydroxy-delta(5)-steroid dehydrogenase (EC 1.1.1.145) (3-beta-hydroxy-5-ene steroid dehydrogenase) (Progesterone reductase); Steroid delta-isomerase (EC 5.3.3.1) (Delta-5-3-ketosteroid isomerase)].
3BHS2_HUMAN
 
NC score 0.799984 (rank : 8) θ value 3.39556e-23 (rank : 9)
Query Neighborhood Hits 27 Target Neighborhood Hits 16 Shared Neighborhood Hits 16
SwissProt Accessions P26439, Q16010, Q53GD4, Q6LDB9 Gene names HSD3B2, HSDB3B
Domain
Architecture
Description 3 beta-hydroxysteroid dehydrogenase/delta 5-->4-isomerase type II (3Beta-HSD II) [Includes: 3-beta-hydroxy-delta(5)-steroid dehydrogenase (EC 1.1.1.145) (3-beta-hydroxy-5-ene steroid dehydrogenase) (Progesterone reductase); Steroid delta-isomerase (EC 5.3.3.1) (Delta-5-3-ketosteroid isomerase)].
3BHS1_HUMAN
 
NC score 0.797345 (rank : 9) θ value 1.6852e-22 (rank : 10)
Query Neighborhood Hits 27 Target Neighborhood Hits 19 Shared Neighborhood Hits 16
SwissProt Accessions P14060, Q14545, Q8IV65 Gene names HSD3B1, 3BH, HSDB3A
Domain
Architecture
Description 3 beta-hydroxysteroid dehydrogenase/delta 5-->4-isomerase type I (3Beta-HSD I) (Trophoblast antigen FDO161G) [Includes: 3-beta-hydroxy- delta(5)-steroid dehydrogenase (EC 1.1.1.145) (3-beta-hydroxy-5-ene steroid dehydrogenase) (Progesterone reductase); Steroid delta- isomerase (EC 5.3.3.1) (Delta-5-3-ketosteroid isomerase)].
3BHS1_MOUSE
 
NC score 0.795951 (rank : 10) θ value 6.84181e-24 (rank : 8)
Query Neighborhood Hits 27 Target Neighborhood Hits 21 Shared Neighborhood Hits 16
SwissProt Accessions P24815, Q7TQ00 Gene names Hsd3b1, Hsd3b
Domain
Architecture
Description 3 beta-hydroxysteroid dehydrogenase/delta 5-->4-isomerase type I (3Beta-HSD I) [Includes: 3-beta-hydroxy-delta(5)-steroid dehydrogenase (EC 1.1.1.145) (3-beta-hydroxy-5-ene steroid dehydrogenase) (Progesterone reductase); Steroid delta-isomerase (EC 5.3.3.1) (Delta- 5-3-ketosteroid isomerase)].
3BHS5_MOUSE
 
NC score 0.789096 (rank : 11) θ value 1.74391e-19 (rank : 11)
Query Neighborhood Hits 27 Target Neighborhood Hits 18 Shared Neighborhood Hits 16
SwissProt Accessions Q61694, Q91X27 Gene names Hsd3b5
Domain
Architecture
Description 3 beta-hydroxysteroid dehydrogenase type 5 (3 beta-hydroxysteroid dehydrogenase type V) (3Beta-HSD V) (NADPH-dependent 3-beta-hydroxy- delta(5)-steroid dehydrogenase) (EC 1.1.1.-) (3-beta-hydroxy-5-ene steroid dehydrogenase) (Progesterone reductase).
3BHS4_MOUSE
 
NC score 0.780677 (rank : 12) θ value 1.24977e-17 (rank : 12)
Query Neighborhood Hits 27 Target Neighborhood Hits 17 Shared Neighborhood Hits 16
SwissProt Accessions Q61767 Gene names Hsd3b4
Domain
Architecture
Description 3 beta-hydroxysteroid dehydrogenase type 4 (3 beta-hydroxysteroid dehydrogenase type IV) (3Beta-HSD IV) (NADPH-dependent 3-beta-hydroxy- delta(5)-steroid dehydrogenase) (EC 1.1.1.-) (3-beta-hydroxy-5-ene steroid dehydrogenase) (Progesterone reductase).
TGDS_HUMAN
 
NC score 0.519026 (rank : 13) θ value 4.92598e-06 (rank : 15)
Query Neighborhood Hits 27 Target Neighborhood Hits 23 Shared Neighborhood Hits 18
SwissProt Accessions O95455, Q5T3Z2, Q9H1T9 Gene names TGDS
Domain
Architecture
Description dTDP-D-glucose 4,6-dehydratase (EC 4.2.1.46).
TGDS_MOUSE
 
NC score 0.518808 (rank : 14) θ value 4.92598e-06 (rank : 16)
Query Neighborhood Hits 27 Target Neighborhood Hits 26 Shared Neighborhood Hits 20
SwissProt Accessions Q8VDR7 Gene names Tgds
Domain
Architecture
Description dTDP-D-glucose 4,6-dehydratase (EC 4.2.1.46).
GALE_HUMAN
 
NC score 0.441911 (rank : 15) θ value 0.000158464 (rank : 17)
Query Neighborhood Hits 27 Target Neighborhood Hits 25 Shared Neighborhood Hits 18
SwissProt Accessions Q14376, Q86W41, Q9BVE3, Q9UJB4 Gene names GALE
Domain
Architecture
Description UDP-glucose 4-epimerase (EC 5.1.3.2) (Galactowaldenase) (UDP-galactose 4-epimerase).
GALE_MOUSE
 
NC score 0.405262 (rank : 16) θ value 0.00134147 (rank : 18)
Query Neighborhood Hits 27 Target Neighborhood Hits 28 Shared Neighborhood Hits 18
SwissProt Accessions Q8R059 Gene names Gale
Domain
Architecture
Description UDP-glucose 4-epimerase (EC 5.1.3.2) (Galactowaldenase) (UDP-galactose 4-epimerase).
UXS1_MOUSE
 
NC score 0.399742 (rank : 17) θ value 2.69671e-12 (rank : 13)
Query Neighborhood Hits 27 Target Neighborhood Hits 19 Shared Neighborhood Hits 10
SwissProt Accessions Q91XL3, Q3U854 Gene names Uxs1
Domain
Architecture

No domain graphic available

Description UDP-glucuronic acid decarboxylase 1 (EC 4.1.1.35) (UDP-glucuronate decarboxylase 1) (UGD) (UXS-1).
UXS1_HUMAN
 
NC score 0.398869 (rank : 18) θ value 3.52202e-12 (rank : 14)
Query Neighborhood Hits 27 Target Neighborhood Hits 19 Shared Neighborhood Hits 10
SwissProt Accessions Q8NBZ7, Q8NBX3, Q9H5C2 Gene names UXS1
Domain
Architecture

No domain graphic available

Description UDP-glucuronic acid decarboxylase 1 (EC 4.1.1.35) (UDP-glucuronate decarboxylase 1) (UGD) (UXS-1).
FCL_HUMAN
 
NC score 0.097177 (rank : 19) θ value θ > 10 (rank : 28)
Query Neighborhood Hits 27 Target Neighborhood Hits 11 Shared Neighborhood Hits 6
SwissProt Accessions Q13630, Q567Q9, Q9UDG7 Gene names TSTA3
Domain
Architecture
Description GDP-L-fucose synthetase (EC 1.1.1.271) (Protein FX) (Red cell NADP(H)- binding protein) (GDP-4-keto-6-deoxy-D-mannose-3,5-epimerase-4- reductase).
FCL_MOUSE
 
NC score 0.090483 (rank : 20) θ value θ > 10 (rank : 29)
Query Neighborhood Hits 27 Target Neighborhood Hits 10 Shared Neighborhood Hits 6
SwissProt Accessions P23591 Gene names Tsta3, P35b, Tstap35b
Domain
Architecture
Description GDP-L-fucose synthetase (EC 1.1.1.271) (Protein FX) (Red cell NADP(H)- binding protein) (GDP-4-keto-6-deoxy-D-mannose-3,5-epimerase-4- reductase) (Transplantation antigen P35B) (Tum-P35B antigen).
GMDS_HUMAN
 
NC score 0.090453 (rank : 21) θ value θ > 10 (rank : 30)
Query Neighborhood Hits 27 Target Neighborhood Hits 13 Shared Neighborhood Hits 6
SwissProt Accessions O60547, O75357, Q5T954, Q6FH09, Q9UGZ3, Q9UJK9 Gene names GMDS
Domain
Architecture
Description GDP-mannose 4,6 dehydratase (EC 4.2.1.47) (GDP-D-mannose dehydratase) (GMD).
GMDS_MOUSE
 
NC score 0.088965 (rank : 22) θ value θ > 10 (rank : 31)
Query Neighborhood Hits 27 Target Neighborhood Hits 13 Shared Neighborhood Hits 6
SwissProt Accessions Q8K0C9 Gene names Gmds
Domain
Architecture

No domain graphic available

Description GDP-mannose 4,6 dehydratase (EC 4.2.1.47) (GDP-D-mannose dehydratase) (GMD).
NDUA9_MOUSE
 
NC score 0.086093 (rank : 23) θ value 0.365318 (rank : 19)
Query Neighborhood Hits 27 Target Neighborhood Hits 6 Shared Neighborhood Hits 6
SwissProt Accessions Q9DC69, Q99JP9 Gene names Ndufa9
Domain
Architecture
Description NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial precursor (EC 1.6.5.3) (EC 1.6.99.3) (NADH-ubiquinone oxidoreductase 39 kDa subunit) (Complex I-39kD) (CI-39kD).
NDUA9_HUMAN
 
NC score 0.066971 (rank : 24) θ value 1.38821 (rank : 21)
Query Neighborhood Hits 27 Target Neighborhood Hits 9 Shared Neighborhood Hits 5
SwissProt Accessions Q16795, Q14076, Q2NKX0 Gene names NDUFA9, NDUFS2L
Domain
Architecture
Description NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial precursor (EC 1.6.5.3) (EC 1.6.99.3) (NADH-ubiquinone oxidoreductase 39 kDa subunit) (Complex I-39kD) (CI-39kD).
BLVRB_MOUSE
 
NC score 0.061545 (rank : 25) θ value 0.62314 (rank : 20)
Query Neighborhood Hits 27 Target Neighborhood Hits 10 Shared Neighborhood Hits 4
SwissProt Accessions Q923D2 Gene names Blvrb
Domain
Architecture

No domain graphic available

Description Flavin reductase (EC 1.5.1.30) (FR) (NADPH-dependent diaphorase) (NADPH-flavin reductase) (FLR) (Biliverdin reductase B) (EC 1.3.1.24) (BVR-B) (Biliverdin-IX beta-reductase).
CRYL1_HUMAN
 
NC score 0.016794 (rank : 26) θ value 8.99809 (rank : 27)
Query Neighborhood Hits 27 Target Neighborhood Hits 12 Shared Neighborhood Hits 3
SwissProt Accessions Q9Y2S2, Q7Z4Z9 Gene names CRYL1, CRY
Domain
Architecture
Description Lambda-crystallin homolog.
IL16_MOUSE
 
NC score 0.016680 (rank : 27) θ value 1.81305 (rank : 22)
Query Neighborhood Hits 27 Target Neighborhood Hits 189 Shared Neighborhood Hits 2
SwissProt Accessions O54824, O70236, Q3TEM4, Q8R0G5 Gene names Il16
Domain
Architecture

No domain graphic available

Description Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).
AK1D1_HUMAN
 
NC score 0.011205 (rank : 28) θ value 6.88961 (rank : 25)
Query Neighborhood Hits 27 Target Neighborhood Hits 29 Shared Neighborhood Hits 4
SwissProt Accessions P51857 Gene names AKR1D1, SRD5B1
Domain
Architecture
Description 3-oxo-5-beta-steroid 4-dehydrogenase (EC 1.3.1.3) (Delta(4)-3- ketosteroid 5-beta-reductase) (Aldo-keto reductase family 1 member D1).
AK1C4_HUMAN
 
NC score 0.011155 (rank : 29) θ value 6.88961 (rank : 24)
Query Neighborhood Hits 27 Target Neighborhood Hits 28 Shared Neighborhood Hits 4
SwissProt Accessions P17516, Q5T6A3, Q8WW84, Q9NS54 Gene names AKR1C4, CHDR
Domain
Architecture
Description Aldo-keto reductase family 1 member C4 (EC 1.1.1.-) (Chlordecone reductase) (EC 1.1.1.225) (CDR) (3-alpha-hydroxysteroid dehydrogenase type I) (EC 1.1.1.50) (3-alpha-HSD1) (Dihydrodiol dehydrogenase 4) (DD4) (HAKRA).
AK1C1_HUMAN
 
NC score 0.011075 (rank : 30) θ value 6.88961 (rank : 23)
Query Neighborhood Hits 27 Target Neighborhood Hits 29 Shared Neighborhood Hits 4
SwissProt Accessions Q04828, P52896, Q5SR15, Q9UCX2 Gene names AKR1C1, DDH, DDH1
Domain
Architecture
Description Aldo-keto reductase family 1 member C1 (EC 1.1.1.-) (20-alpha- hydroxysteroid dehydrogenase) (EC 1.1.1.149) (20-alpha-HSD) (Trans- 1,2-dihydrobenzene-1,2-diol dehydrogenase) (EC 1.3.1.20) (High- affinity hepatic bile acid-binding protein) (HBAB) (Chlordecone reductase homolog HAKRC) (Dihydrodiol dehydrogenase 1/2) (DD1/DD2).
AT12A_HUMAN
 
NC score 0.002992 (rank : 31) θ value 8.99809 (rank : 26)
Query Neighborhood Hits 27 Target Neighborhood Hits 65 Shared Neighborhood Hits 2
SwissProt Accessions P54707, Q13816, Q13817, Q16734 Gene names ATP12A, ATP1AL1
Domain
Architecture
Description Potassium-transporting ATPase alpha chain 2 (EC 3.6.3.10) (Proton pump) (Non-gastric H(+)/K(+) ATPase subunit alpha).