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Network neighborhood for query Sequence : TPP2_HUMAN

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TPP2_HUMAN
SwissProt Accessions	P29144	Gene names	TPP2
Domain Architecture
Description	Tripeptidyl-peptidase 2 (EC 3.4.14.10) (Tripeptidyl-peptidase II) (TPP-II) (Tripeptidyl aminopeptidase).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

TPP2_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	30	Target Neighborhood Hits	30	Shared Neighborhood Hits	30
SwissProt Accessions	P29144	Gene names	TPP2
Domain Architecture
Description	Tripeptidyl-peptidase 2 (EC 3.4.14.10) (Tripeptidyl-peptidase II) (TPP-II) (Tripeptidyl aminopeptidase).

TPP2_MOUSE
θ value	0 (rank : 2)	NC score	0.997785 (rank : 2)
Query Neighborhood Hits	30	Target Neighborhood Hits	24	Shared Neighborhood Hits	17
SwissProt Accessions	Q64514	Gene names	Tpp2
Domain Architecture
Description	Tripeptidyl-peptidase 2 (EC 3.4.14.10) (Tripeptidyl-peptidase II) (TPP-II) (Tripeptidyl aminopeptidase).

MBTP1_MOUSE
θ value	3.89403e-11 (rank : 3)	NC score	0.378130 (rank : 3)
Query Neighborhood Hits	30	Target Neighborhood Hits	26	Shared Neighborhood Hits	4
SwissProt Accessions	Q9WTZ2, Q6PG67	Gene names	Mbtps1, S1p, Ski1
Domain Architecture
Description	Membrane-bound transcription factor site 1 protease precursor (EC 3.4.21.-) (S1P endopeptidase) (Site-1 protease) (Subtilisin/kexin isozyme 1) (SKI-1) (Sterol-regulated luminal protease).

MBTP1_HUMAN
θ value	6.64225e-11 (rank : 4)	NC score	0.375467 (rank : 4)
Query Neighborhood Hits	30	Target Neighborhood Hits	28	Shared Neighborhood Hits	4
SwissProt Accessions	Q14703, Q9UF67	Gene names	MBTPS1, KIAA0091, S1P, SKI1
Domain Architecture	No domain graphic available
Description	Membrane-bound transcription factor site 1 protease precursor (EC 3.4.21.-) (S1P endopeptidase) (Site-1 protease) (Subtilisin/kexin- isozyme 1) (SKI-1).

CSPG3_MOUSE
θ value	0.813845 (rank : 5)	NC score	0.020690 (rank : 16)
Query Neighborhood Hits	30	Target Neighborhood Hits	657	Shared Neighborhood Hits	5
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

CNTN1_MOUSE
θ value	1.38821 (rank : 6)	NC score	0.012059 (rank : 21)
Query Neighborhood Hits	30	Target Neighborhood Hits	422	Shared Neighborhood Hits	3
SwissProt Accessions	P12960, Q6NXV7, Q8BR42, Q8C6A0	Gene names	Cntn1
Domain Architecture
Description	Contactin-1 precursor (Neural cell surface protein F3).

HECD1_HUMAN
θ value	1.38821 (rank : 7)	NC score	0.026790 (rank : 10)
Query Neighborhood Hits	30	Target Neighborhood Hits	371	Shared Neighborhood Hits	6
SwissProt Accessions	Q9ULT8, Q6P445, Q86VJ1, Q96F34, Q9UFZ7	Gene names	HECTD1, KIAA1131
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase HECTD1 (HECT domain-containing protein 1) (E3 ligase for inhibin receptor) (EULIR).

PTPRR_HUMAN
θ value	1.81305 (rank : 8)	NC score	0.015593 (rank : 19)
Query Neighborhood Hits	30	Target Neighborhood Hits	77	Shared Neighborhood Hits	4
SwissProt Accessions	Q15256, O00342, Q92682, Q9UE65	Gene names	PTPRR, ECPTP
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase R precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase PCPTP1) (NC-PTPCOM1) (Ch-1PTPase).

CNTN1_HUMAN
θ value	2.36792 (rank : 9)	NC score	0.011198 (rank : 23)
Query Neighborhood Hits	30	Target Neighborhood Hits	431	Shared Neighborhood Hits	3
SwissProt Accessions	Q12860, Q12861, Q14030, Q8N466	Gene names	CNTN1
Domain Architecture
Description	Contactin-1 precursor (Neural cell surface protein F3) (Glycoprotein gp135).

PCSK9_MOUSE
θ value	2.36792 (rank : 10)	NC score	0.049684 (rank : 5)
Query Neighborhood Hits	30	Target Neighborhood Hits	16	Shared Neighborhood Hits	4
SwissProt Accessions	Q80W65, Q3UEH7, Q8BXW9, Q8CFT6	Gene names	Pcsk9, Narc1
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 9 precursor (EC 3.4.21.-) (Proprotein convertase PC9) (Subtilisin/kexin-like protease PC9) (Neural apoptosis-regulated convertase 1) (NARC-1).

BPAEA_MOUSE
θ value	3.0926 (rank : 11)	NC score	0.006422 (rank : 30)
Query Neighborhood Hits	30	Target Neighborhood Hits	1480	Shared Neighborhood Hits	7
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

CSKI1_MOUSE
θ value	3.0926 (rank : 12)	NC score	0.014435 (rank : 20)
Query Neighborhood Hits	30	Target Neighborhood Hits	1031	Shared Neighborhood Hits	6
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

GOGA2_HUMAN
θ value	3.0926 (rank : 13)	NC score	0.009987 (rank : 25)
Query Neighborhood Hits	30	Target Neighborhood Hits	856	Shared Neighborhood Hits	5
SwissProt Accessions	Q08379, Q9BRB0, Q9NYF9	Gene names	GOLGA2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130) (Gm130 autoantigen) (Golgin-95).

HCFC1_HUMAN
θ value	3.0926 (rank : 14)	NC score	0.024210 (rank : 13)
Query Neighborhood Hits	30	Target Neighborhood Hits	331	Shared Neighborhood Hits	5
SwissProt Accessions	P51610, Q6P4G5	Gene names	HCFC1, HCF1
Domain Architecture	No domain graphic available
Description	Host cell factor (HCF) (HCF-1) (C1 factor) (VP16 accessory protein) (VCAF) (CFF) [Contains: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N-terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C- terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6].

HCFC1_MOUSE
θ value	3.0926 (rank : 15)	NC score	0.023795 (rank : 14)
Query Neighborhood Hits	30	Target Neighborhood Hits	348	Shared Neighborhood Hits	4
SwissProt Accessions	Q61191, Q684R1, Q7TSB0, Q8C2D0, Q9QWH2	Gene names	Hcfc1
Domain Architecture	No domain graphic available
Description	Host cell factor (HCF) (HCF-1) (C1 factor) [Contains: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N- terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C-terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6].

GSCR1_HUMAN
θ value	4.03905 (rank : 16)	NC score	0.026139 (rank : 11)
Query Neighborhood Hits	30	Target Neighborhood Hits	674	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

PCSK9_HUMAN
θ value	4.03905 (rank : 17)	NC score	0.043048 (rank : 6)
Query Neighborhood Hits	30	Target Neighborhood Hits	20	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NBP7, Q5PSM5	Gene names	PCSK9, NARC1
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 9 precursor (EC 3.4.21.-) (Proprotein convertase PC9) (Subtilisin/kexin-like protease PC9) (Neural apoptosis-regulated convertase 1) (NARC-1).

PP25_HUMAN
θ value	4.03905 (rank : 18)	NC score	0.038348 (rank : 7)
Query Neighborhood Hits	30	Target Neighborhood Hits	3	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y547, Q9Y684	Gene names	C1orf41
Domain Architecture	No domain graphic available
Description	Placental protein 25 (PP25).

CRSP3_HUMAN
θ value	5.27518 (rank : 19)	NC score	0.024855 (rank : 12)
Query Neighborhood Hits	30	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	Q9ULK4, O95403, Q9H0J2, Q9NTT9, Q9NTU0, Q9Y5P7, Q9Y667	Gene names	CRSP3, ARC130, DRIP130, KIAA1216, SUR2
Domain Architecture	No domain graphic available
Description	CRSP complex subunit 3 (Cofactor required for Sp1 transcriptional activation subunit 3) (Transcriptional coactivator CRSP130) (Vitamin D3 receptor-interacting protein complex 130 kDa component) (DRIP130) (Activator-recruited cofactor 130 kDa component) (ARC130).

MYG1_HUMAN
θ value	5.27518 (rank : 20)	NC score	0.021505 (rank : 15)
Query Neighborhood Hits	30	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	Q9HB07	Gene names	C12orf10
Domain Architecture
Description	UPF0160 protein MYG1.

PTN13_HUMAN
θ value	5.27518 (rank : 21)	NC score	0.009607 (rank : 27)
Query Neighborhood Hits	30	Target Neighborhood Hits	471	Shared Neighborhood Hits	4
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

LPPRC_HUMAN
θ value	6.88961 (rank : 22)	NC score	0.031446 (rank : 9)
Query Neighborhood Hits	30	Target Neighborhood Hits	45	Shared Neighborhood Hits	3
SwissProt Accessions	P42704	Gene names	LRPPRC, LRP130
Domain Architecture	No domain graphic available
Description	130 kDa leucine-rich protein (LRP 130) (GP130) (Leucine-rich PPR motif-containing protein).

MORC4_HUMAN
θ value	6.88961 (rank : 23)	NC score	0.011627 (rank : 22)
Query Neighborhood Hits	30	Target Neighborhood Hits	244	Shared Neighborhood Hits	4
SwissProt Accessions	Q8TE76, Q5JUK7, Q96MZ2, Q9HAI7	Gene names	MORC4, ZCWCC2
Domain Architecture	No domain graphic available
Description	MORC family CW-type zinc finger protein 4 (Zinc finger CW-type coiled- coil domain protein 2).

ORC2_MOUSE
θ value	6.88961 (rank : 24)	NC score	0.017172 (rank : 17)
Query Neighborhood Hits	30	Target Neighborhood Hits	41	Shared Neighborhood Hits	2
SwissProt Accessions	Q60862	Gene names	Orc2l, Orc2
Domain Architecture
Description	Origin recognition complex subunit 2.

PP25_MOUSE
θ value	6.88961 (rank : 25)	NC score	0.032752 (rank : 8)
Query Neighborhood Hits	30	Target Neighborhood Hits	3	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D6H2	Gene names
Domain Architecture	No domain graphic available
Description	Placental protein 25 homolog (PP25).

AL3B2_HUMAN
θ value	8.99809 (rank : 26)	NC score	0.015708 (rank : 18)
Query Neighborhood Hits	30	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	P48448, Q8NAL5, Q96IB2	Gene names	ALDH3B2, ALDH8
Domain Architecture
Description	Aldehyde dehydrogenase 3B2 (EC 1.2.1.5) (Aldehyde dehydrogenase 8).

CK5P2_MOUSE
θ value	8.99809 (rank : 27)	NC score	0.008452 (rank : 29)
Query Neighborhood Hits	30	Target Neighborhood Hits	1151	Shared Neighborhood Hits	6
SwissProt Accessions	Q8K389, Q6PCN1, Q6ZPL0	Gene names	Cdk5rap2, Kiaa1633
Domain Architecture	No domain graphic available
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48).

CSKI1_HUMAN
θ value	8.99809 (rank : 28)	NC score	0.010962 (rank : 24)
Query Neighborhood Hits	30	Target Neighborhood Hits	997	Shared Neighborhood Hits	6
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

LPXN_MOUSE
θ value	8.99809 (rank : 29)	NC score	0.009865 (rank : 26)
Query Neighborhood Hits	30	Target Neighborhood Hits	227	Shared Neighborhood Hits	5
SwissProt Accessions	Q99N69	Gene names	Lpxn
Domain Architecture	No domain graphic available
Description	Leupaxin.

SULF1_HUMAN
θ value	8.99809 (rank : 30)	NC score	0.008500 (rank : 28)
Query Neighborhood Hits	30	Target Neighborhood Hits	55	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IWU6, Q86YV8, Q8NCA2, Q9UPS5	Gene names	SULF1, KIAA1077
Domain Architecture
Description	Extracellular sulfatase Sulf-1 precursor (EC 3.1.6.-) (HSulf-1).

Hits sorted by NC score

TPP2_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	30	Target Neighborhood Hits	30	Shared Neighborhood Hits	30
SwissProt Accessions	P29144	Gene names	TPP2
Domain Architecture
Description	Tripeptidyl-peptidase 2 (EC 3.4.14.10) (Tripeptidyl-peptidase II) (TPP-II) (Tripeptidyl aminopeptidase).

TPP2_MOUSE
NC score	0.997785 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	30	Target Neighborhood Hits	24	Shared Neighborhood Hits	17
SwissProt Accessions	Q64514	Gene names	Tpp2
Domain Architecture
Description	Tripeptidyl-peptidase 2 (EC 3.4.14.10) (Tripeptidyl-peptidase II) (TPP-II) (Tripeptidyl aminopeptidase).

MBTP1_MOUSE
NC score	0.378130 (rank : 3)	θ value	3.89403e-11 (rank : 3)
Query Neighborhood Hits	30	Target Neighborhood Hits	26	Shared Neighborhood Hits	4
SwissProt Accessions	Q9WTZ2, Q6PG67	Gene names	Mbtps1, S1p, Ski1
Domain Architecture
Description	Membrane-bound transcription factor site 1 protease precursor (EC 3.4.21.-) (S1P endopeptidase) (Site-1 protease) (Subtilisin/kexin isozyme 1) (SKI-1) (Sterol-regulated luminal protease).

MBTP1_HUMAN
NC score	0.375467 (rank : 4)	θ value	6.64225e-11 (rank : 4)
Query Neighborhood Hits	30	Target Neighborhood Hits	28	Shared Neighborhood Hits	4
SwissProt Accessions	Q14703, Q9UF67	Gene names	MBTPS1, KIAA0091, S1P, SKI1
Domain Architecture	No domain graphic available
Description	Membrane-bound transcription factor site 1 protease precursor (EC 3.4.21.-) (S1P endopeptidase) (Site-1 protease) (Subtilisin/kexin- isozyme 1) (SKI-1).

PCSK9_MOUSE
NC score	0.049684 (rank : 5)	θ value	2.36792 (rank : 10)
Query Neighborhood Hits	30	Target Neighborhood Hits	16	Shared Neighborhood Hits	4
SwissProt Accessions	Q80W65, Q3UEH7, Q8BXW9, Q8CFT6	Gene names	Pcsk9, Narc1
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 9 precursor (EC 3.4.21.-) (Proprotein convertase PC9) (Subtilisin/kexin-like protease PC9) (Neural apoptosis-regulated convertase 1) (NARC-1).

PCSK9_HUMAN
NC score	0.043048 (rank : 6)	θ value	4.03905 (rank : 17)
Query Neighborhood Hits	30	Target Neighborhood Hits	20	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NBP7, Q5PSM5	Gene names	PCSK9, NARC1
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 9 precursor (EC 3.4.21.-) (Proprotein convertase PC9) (Subtilisin/kexin-like protease PC9) (Neural apoptosis-regulated convertase 1) (NARC-1).

PP25_HUMAN
NC score	0.038348 (rank : 7)	θ value	4.03905 (rank : 18)
Query Neighborhood Hits	30	Target Neighborhood Hits	3	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y547, Q9Y684	Gene names	C1orf41
Domain Architecture	No domain graphic available
Description	Placental protein 25 (PP25).

PP25_MOUSE
NC score	0.032752 (rank : 8)	θ value	6.88961 (rank : 25)
Query Neighborhood Hits	30	Target Neighborhood Hits	3	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D6H2	Gene names
Domain Architecture	No domain graphic available
Description	Placental protein 25 homolog (PP25).

LPPRC_HUMAN
NC score	0.031446 (rank : 9)	θ value	6.88961 (rank : 22)
Query Neighborhood Hits	30	Target Neighborhood Hits	45	Shared Neighborhood Hits	3
SwissProt Accessions	P42704	Gene names	LRPPRC, LRP130
Domain Architecture	No domain graphic available
Description	130 kDa leucine-rich protein (LRP 130) (GP130) (Leucine-rich PPR motif-containing protein).

HECD1_HUMAN
NC score	0.026790 (rank : 10)	θ value	1.38821 (rank : 7)
Query Neighborhood Hits	30	Target Neighborhood Hits	371	Shared Neighborhood Hits	6
SwissProt Accessions	Q9ULT8, Q6P445, Q86VJ1, Q96F34, Q9UFZ7	Gene names	HECTD1, KIAA1131
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase HECTD1 (HECT domain-containing protein 1) (E3 ligase for inhibin receptor) (EULIR).

GSCR1_HUMAN
NC score	0.026139 (rank : 11)	θ value	4.03905 (rank : 16)
Query Neighborhood Hits	30	Target Neighborhood Hits	674	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

CRSP3_HUMAN
NC score	0.024855 (rank : 12)	θ value	5.27518 (rank : 19)
Query Neighborhood Hits	30	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	Q9ULK4, O95403, Q9H0J2, Q9NTT9, Q9NTU0, Q9Y5P7, Q9Y667	Gene names	CRSP3, ARC130, DRIP130, KIAA1216, SUR2
Domain Architecture	No domain graphic available
Description	CRSP complex subunit 3 (Cofactor required for Sp1 transcriptional activation subunit 3) (Transcriptional coactivator CRSP130) (Vitamin D3 receptor-interacting protein complex 130 kDa component) (DRIP130) (Activator-recruited cofactor 130 kDa component) (ARC130).

HCFC1_HUMAN
NC score	0.024210 (rank : 13)	θ value	3.0926 (rank : 14)
Query Neighborhood Hits	30	Target Neighborhood Hits	331	Shared Neighborhood Hits	5
SwissProt Accessions	P51610, Q6P4G5	Gene names	HCFC1, HCF1
Domain Architecture	No domain graphic available
Description	Host cell factor (HCF) (HCF-1) (C1 factor) (VP16 accessory protein) (VCAF) (CFF) [Contains: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N-terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C- terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6].

HCFC1_MOUSE
NC score	0.023795 (rank : 14)	θ value	3.0926 (rank : 15)
Query Neighborhood Hits	30	Target Neighborhood Hits	348	Shared Neighborhood Hits	4
SwissProt Accessions	Q61191, Q684R1, Q7TSB0, Q8C2D0, Q9QWH2	Gene names	Hcfc1
Domain Architecture	No domain graphic available
Description	Host cell factor (HCF) (HCF-1) (C1 factor) [Contains: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N- terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C-terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6].

MYG1_HUMAN
NC score	0.021505 (rank : 15)	θ value	5.27518 (rank : 20)
Query Neighborhood Hits	30	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	Q9HB07	Gene names	C12orf10
Domain Architecture
Description	UPF0160 protein MYG1.

CSPG3_MOUSE
NC score	0.020690 (rank : 16)	θ value	0.813845 (rank : 5)
Query Neighborhood Hits	30	Target Neighborhood Hits	657	Shared Neighborhood Hits	5
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

ORC2_MOUSE
NC score	0.017172 (rank : 17)	θ value	6.88961 (rank : 24)
Query Neighborhood Hits	30	Target Neighborhood Hits	41	Shared Neighborhood Hits	2
SwissProt Accessions	Q60862	Gene names	Orc2l, Orc2
Domain Architecture
Description	Origin recognition complex subunit 2.

AL3B2_HUMAN
NC score	0.015708 (rank : 18)	θ value	8.99809 (rank : 26)
Query Neighborhood Hits	30	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	P48448, Q8NAL5, Q96IB2	Gene names	ALDH3B2, ALDH8
Domain Architecture
Description	Aldehyde dehydrogenase 3B2 (EC 1.2.1.5) (Aldehyde dehydrogenase 8).

PTPRR_HUMAN
NC score	0.015593 (rank : 19)	θ value	1.81305 (rank : 8)
Query Neighborhood Hits	30	Target Neighborhood Hits	77	Shared Neighborhood Hits	4
SwissProt Accessions	Q15256, O00342, Q92682, Q9UE65	Gene names	PTPRR, ECPTP
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase R precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase PCPTP1) (NC-PTPCOM1) (Ch-1PTPase).

CSKI1_MOUSE
NC score	0.014435 (rank : 20)	θ value	3.0926 (rank : 12)
Query Neighborhood Hits	30	Target Neighborhood Hits	1031	Shared Neighborhood Hits	6
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

CNTN1_MOUSE
NC score	0.012059 (rank : 21)	θ value	1.38821 (rank : 6)
Query Neighborhood Hits	30	Target Neighborhood Hits	422	Shared Neighborhood Hits	3
SwissProt Accessions	P12960, Q6NXV7, Q8BR42, Q8C6A0	Gene names	Cntn1
Domain Architecture
Description	Contactin-1 precursor (Neural cell surface protein F3).

MORC4_HUMAN
NC score	0.011627 (rank : 22)	θ value	6.88961 (rank : 23)
Query Neighborhood Hits	30	Target Neighborhood Hits	244	Shared Neighborhood Hits	4
SwissProt Accessions	Q8TE76, Q5JUK7, Q96MZ2, Q9HAI7	Gene names	MORC4, ZCWCC2
Domain Architecture	No domain graphic available
Description	MORC family CW-type zinc finger protein 4 (Zinc finger CW-type coiled- coil domain protein 2).

CNTN1_HUMAN
NC score	0.011198 (rank : 23)	θ value	2.36792 (rank : 9)
Query Neighborhood Hits	30	Target Neighborhood Hits	431	Shared Neighborhood Hits	3
SwissProt Accessions	Q12860, Q12861, Q14030, Q8N466	Gene names	CNTN1
Domain Architecture
Description	Contactin-1 precursor (Neural cell surface protein F3) (Glycoprotein gp135).

CSKI1_HUMAN
NC score	0.010962 (rank : 24)	θ value	8.99809 (rank : 28)
Query Neighborhood Hits	30	Target Neighborhood Hits	997	Shared Neighborhood Hits	6
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

GOGA2_HUMAN
NC score	0.009987 (rank : 25)	θ value	3.0926 (rank : 13)
Query Neighborhood Hits	30	Target Neighborhood Hits	856	Shared Neighborhood Hits	5
SwissProt Accessions	Q08379, Q9BRB0, Q9NYF9	Gene names	GOLGA2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130) (Gm130 autoantigen) (Golgin-95).

LPXN_MOUSE
NC score	0.009865 (rank : 26)	θ value	8.99809 (rank : 29)
Query Neighborhood Hits	30	Target Neighborhood Hits	227	Shared Neighborhood Hits	5
SwissProt Accessions	Q99N69	Gene names	Lpxn
Domain Architecture	No domain graphic available
Description	Leupaxin.

PTN13_HUMAN
NC score	0.009607 (rank : 27)	θ value	5.27518 (rank : 21)
Query Neighborhood Hits	30	Target Neighborhood Hits	471	Shared Neighborhood Hits	4
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

SULF1_HUMAN
NC score	0.008500 (rank : 28)	θ value	8.99809 (rank : 30)
Query Neighborhood Hits	30	Target Neighborhood Hits	55	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IWU6, Q86YV8, Q8NCA2, Q9UPS5	Gene names	SULF1, KIAA1077
Domain Architecture
Description	Extracellular sulfatase Sulf-1 precursor (EC 3.1.6.-) (HSulf-1).

CK5P2_MOUSE
NC score	0.008452 (rank : 29)	θ value	8.99809 (rank : 27)
Query Neighborhood Hits	30	Target Neighborhood Hits	1151	Shared Neighborhood Hits	6
SwissProt Accessions	Q8K389, Q6PCN1, Q6ZPL0	Gene names	Cdk5rap2, Kiaa1633
Domain Architecture	No domain graphic available
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48).

BPAEA_MOUSE
NC score	0.006422 (rank : 30)	θ value	3.0926 (rank : 11)
Query Neighborhood Hits	30	Target Neighborhood Hits	1480	Shared Neighborhood Hits	7
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).