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Network neighborhood for query Sequence : TAGL_HUMAN

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TAGL_HUMAN
SwissProt Accessions	Q01995, O15542	Gene names	TAGLN, SM22, WS3-10
Domain Architecture
Description	Transgelin (Smooth muscle protein 22-alpha) (SM22-alpha) (WS3-10) (22 kDa actin-binding protein).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

TAGL_HUMAN
θ value	1.58745e-113 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	32	Target Neighborhood Hits	32	Shared Neighborhood Hits	32
SwissProt Accessions	Q01995, O15542	Gene names	TAGLN, SM22, WS3-10
Domain Architecture
Description	Transgelin (Smooth muscle protein 22-alpha) (SM22-alpha) (WS3-10) (22 kDa actin-binding protein).

TAGL_MOUSE
θ value	4.32305e-111 (rank : 2)	NC score	0.999651 (rank : 2)
Query Neighborhood Hits	32	Target Neighborhood Hits	33	Shared Neighborhood Hits	32
SwissProt Accessions	P37804, Q545W0	Gene names	Tagln, Sm22, Sm22a
Domain Architecture
Description	Transgelin (Smooth muscle protein 22-alpha) (SM22-alpha) (Actin- associated protein p27).

TAGL3_HUMAN
θ value	2.92676e-75 (rank : 3)	NC score	0.991087 (rank : 3)
Query Neighborhood Hits	32	Target Neighborhood Hits	33	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UI15, Q96A74	Gene names	TAGLN3, NP25
Domain Architecture
Description	Transgelin-3 (Neuronal protein NP25) (Neuronal protein 22) (NP22).

TAGL3_MOUSE
θ value	4.99229e-75 (rank : 4)	NC score	0.990983 (rank : 4)
Query Neighborhood Hits	32	Target Neighborhood Hits	33	Shared Neighborhood Hits	27
SwissProt Accessions	Q9R1Q8	Gene names	Tagln3, Np25
Domain Architecture
Description	Transgelin-3 (Neuronal protein NP25).

TAGL2_HUMAN
θ value	1.04096e-72 (rank : 5)	NC score	0.988329 (rank : 5)
Query Neighborhood Hits	32	Target Neighborhood Hits	35	Shared Neighborhood Hits	28
SwissProt Accessions	P37802, Q5JRQ6, Q5JRQ7, Q9BUH5, Q9H4P0	Gene names	TAGLN2, KIAA0120
Domain Architecture
Description	Transgelin-2 (SM22-alpha homolog).

TAGL2_MOUSE
θ value	2.17053e-70 (rank : 6)	NC score	0.987394 (rank : 6)
Query Neighborhood Hits	32	Target Neighborhood Hits	42	Shared Neighborhood Hits	30
SwissProt Accessions	Q9WVA4	Gene names	Tagln2
Domain Architecture
Description	Transgelin-2.

CNN3_MOUSE
θ value	1.73584e-35 (rank : 7)	NC score	0.890392 (rank : 9)
Query Neighborhood Hits	32	Target Neighborhood Hits	45	Shared Neighborhood Hits	31
SwissProt Accessions	Q9DAW9, Q3TW23	Gene names	Cnn3
Domain Architecture	No domain graphic available
Description	Calponin-3 (Calponin, acidic isoform).

CNN3_HUMAN
θ value	2.26708e-35 (rank : 8)	NC score	0.890182 (rank : 10)
Query Neighborhood Hits	32	Target Neighborhood Hits	43	Shared Neighborhood Hits	31
SwissProt Accessions	Q15417	Gene names	CNN3
Domain Architecture
Description	Calponin-3 (Calponin, acidic isoform).

CNN1_HUMAN
θ value	8.06329e-33 (rank : 9)	NC score	0.892756 (rank : 8)
Query Neighborhood Hits	32	Target Neighborhood Hits	38	Shared Neighborhood Hits	29
SwissProt Accessions	P51911, O00638, Q15416, Q8IY93, Q99438	Gene names	CNN1
Domain Architecture
Description	Calponin-1 (Calponin H1, smooth muscle) (Basic calponin).

CNN1_MOUSE
θ value	8.06329e-33 (rank : 10)	NC score	0.893605 (rank : 7)
Query Neighborhood Hits	32	Target Neighborhood Hits	37	Shared Neighborhood Hits	29
SwissProt Accessions	Q08091	Gene names	Cnn1
Domain Architecture
Description	Calponin-1 (Calponin H1, smooth muscle) (Basic calponin).

CNN2_MOUSE
θ value	2.42779e-29 (rank : 11)	NC score	0.883676 (rank : 11)
Query Neighborhood Hits	32	Target Neighborhood Hits	39	Shared Neighborhood Hits	31
SwissProt Accessions	Q08093	Gene names	Cnn2
Domain Architecture
Description	Calponin-2 (Calponin H2, smooth muscle) (Neutral calponin).

CNN2_HUMAN
θ value	9.2256e-29 (rank : 12)	NC score	0.883077 (rank : 12)
Query Neighborhood Hits	32	Target Neighborhood Hits	37	Shared Neighborhood Hits	29
SwissProt Accessions	Q99439, Q92578	Gene names	CNN2
Domain Architecture
Description	Calponin-2 (Calponin H2, smooth muscle) (Neutral calponin).

VAV_MOUSE
θ value	2.44474e-05 (rank : 13)	NC score	0.221492 (rank : 14)
Query Neighborhood Hits	32	Target Neighborhood Hits	430	Shared Neighborhood Hits	31
SwissProt Accessions	P27870, Q8BTV7	Gene names	Vav1, Vav
Domain Architecture
Description	Proto-oncogene vav (p95vav).

VAV_HUMAN
θ value	4.1701e-05 (rank : 14)	NC score	0.213892 (rank : 16)
Query Neighborhood Hits	32	Target Neighborhood Hits	452	Shared Neighborhood Hits	31
SwissProt Accessions	P15498, Q15860	Gene names	VAV1, VAV
Domain Architecture
Description	Proto-oncogene vav.

VAV3_MOUSE
θ value	0.000270298 (rank : 15)	NC score	0.220660 (rank : 15)
Query Neighborhood Hits	32	Target Neighborhood Hits	404	Shared Neighborhood Hits	29
SwissProt Accessions	Q9R0C8, Q7TS85	Gene names	Vav3
Domain Architecture
Description	Protein vav-3.

VAV3_HUMAN
θ value	0.00134147 (rank : 16)	NC score	0.207689 (rank : 17)
Query Neighborhood Hits	32	Target Neighborhood Hits	398	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UKW4, O95230, Q9Y5X8	Gene names	VAV3
Domain Architecture
Description	Protein vav-3.

VAV2_HUMAN
θ value	0.00298849 (rank : 17)	NC score	0.204491 (rank : 18)
Query Neighborhood Hits	32	Target Neighborhood Hits	453	Shared Neighborhood Hits	31
SwissProt Accessions	P52735	Gene names	VAV2
Domain Architecture
Description	Protein vav-2.

ARHG6_MOUSE
θ value	0.00665767 (rank : 18)	NC score	0.197948 (rank : 20)
Query Neighborhood Hits	32	Target Neighborhood Hits	394	Shared Neighborhood Hits	29
SwissProt Accessions	Q8K4I3, Q8C9V4	Gene names	Arhgef6
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6).

LRCH1_HUMAN
θ value	0.00665767 (rank : 19)	NC score	0.190746 (rank : 21)
Query Neighborhood Hits	32	Target Neighborhood Hits	266	Shared Neighborhood Hits	29
SwissProt Accessions	Q9Y2L9, Q7Z5F6, Q7Z5F7	Gene names	LRCH1, CHDC1, KIAA1016
Domain Architecture
Description	Leucine-rich repeats and calponin homology domain-containing protein 1 (Calponin homology domain-containing protein 1) (Neuronal protein 81) (NP81).

LRCH1_MOUSE
θ value	0.00869519 (rank : 20)	NC score	0.188242 (rank : 22)
Query Neighborhood Hits	32	Target Neighborhood Hits	264	Shared Neighborhood Hits	29
SwissProt Accessions	P62046	Gene names	Lrch1, Chdc1, Kiaa1016
Domain Architecture
Description	Leucine-rich repeats and calponin homology domain-containing protein 1 (Calponin homology domain-containing protein 1).

VAV2_MOUSE
θ value	0.00869519 (rank : 21)	NC score	0.203707 (rank : 19)
Query Neighborhood Hits	32	Target Neighborhood Hits	456	Shared Neighborhood Hits	31
SwissProt Accessions	Q60992	Gene names	Vav2
Domain Architecture
Description	Protein vav-2.

LRCH3_HUMAN
θ value	0.0330416 (rank : 22)	NC score	0.165616 (rank : 24)
Query Neighborhood Hits	32	Target Neighborhood Hits	270	Shared Neighborhood Hits	29
SwissProt Accessions	Q96II8, Q96FP9, Q9NT52	Gene names	LRCH3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and calponin homology domain-containing protein 3 precursor.

LRCH4_MOUSE
θ value	0.0563607 (rank : 23)	NC score	0.148827 (rank : 28)
Query Neighborhood Hits	32	Target Neighborhood Hits	302	Shared Neighborhood Hits	27
SwissProt Accessions	Q921G6	Gene names	Lrch4
Domain Architecture
Description	Leucine-rich repeats and calponin homology domain-containing protein 4.

LMO7_HUMAN
θ value	0.0961366 (rank : 24)	NC score	0.329590 (rank : 13)
Query Neighborhood Hits	32	Target Neighborhood Hits	507	Shared Neighborhood Hits	29
SwissProt Accessions	Q8WWI1, O15462, O95346, Q9UKC1, Q9UQM5, Q9Y6A7	Gene names	LMO7, FBX20, FBXO20, KIAA0858
Domain Architecture
Description	LIM domain only protein 7 (LOMP) (F-box only protein 20).

LRCH4_HUMAN
θ value	0.0961366 (rank : 25)	NC score	0.135429 (rank : 29)
Query Neighborhood Hits	32	Target Neighborhood Hits	305	Shared Neighborhood Hits	25
SwissProt Accessions	O75427, Q8WV85, Q96ID0	Gene names	LRCH4, LRN, LRRN4
Domain Architecture
Description	Leucine-rich repeats and calponin homology domain-containing protein 4 (Leucine-rich neuronal protein).

ARHG6_HUMAN
θ value	0.125558 (rank : 26)	NC score	0.178356 (rank : 23)
Query Neighborhood Hits	32	Target Neighborhood Hits	376	Shared Neighborhood Hits	29
SwissProt Accessions	Q15052, Q15396, Q5JQ66, Q86XH0	Gene names	ARHGEF6, COOL2, KIAA0006, PIXA
Domain Architecture
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6) (PAK-interacting exchange factor alpha) (Alpha-Pix) (COOL-2).

LRCH2_HUMAN
θ value	0.365318 (rank : 27)	NC score	0.155382 (rank : 25)
Query Neighborhood Hits	32	Target Neighborhood Hits	315	Shared Neighborhood Hits	28
SwissProt Accessions	Q5VUJ6, Q9HA88, Q9P233	Gene names	LRCH2, KIAA1495
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and calponin homology domain-containing protein 2.

LRCH2_MOUSE
θ value	0.365318 (rank : 28)	NC score	0.153518 (rank : 27)
Query Neighborhood Hits	32	Target Neighborhood Hits	287	Shared Neighborhood Hits	28
SwissProt Accessions	Q3UMG5, Q7TNP9, Q80TC9	Gene names	Lrch2, Kiaa1495
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and calponin homology domain-containing protein 2.

LRCH3_MOUSE
θ value	0.365318 (rank : 29)	NC score	0.154939 (rank : 26)
Query Neighborhood Hits	32	Target Neighborhood Hits	257	Shared Neighborhood Hits	29
SwissProt Accessions	Q8BVU0, Q3U222, Q3UZ74	Gene names	Lrch3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and calponin homology domain-containing protein 3 precursor.

IQGA1_HUMAN
θ value	0.62314 (rank : 30)	NC score	0.074058 (rank : 33)
Query Neighborhood Hits	32	Target Neighborhood Hits	250	Shared Neighborhood Hits	13
SwissProt Accessions	P46940	Gene names	IQGAP1, KIAA0051
Domain Architecture
Description	Ras GTPase-activating-like protein IQGAP1 (p195).

IQGA1_MOUSE
θ value	0.62314 (rank : 31)	NC score	0.075104 (rank : 31)
Query Neighborhood Hits	32	Target Neighborhood Hits	219	Shared Neighborhood Hits	13
SwissProt Accessions	Q9JKF1	Gene names	Iqgap1
Domain Architecture
Description	Ras GTPase-activating-like protein IQGAP1.

RNH2B_MOUSE
θ value	1.38821 (rank : 32)	NC score	0.036601 (rank : 36)
Query Neighborhood Hits	32	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	Q80ZV0, Q9D014	Gene names	Dleu8, Rnaseh2b
Domain Architecture	No domain graphic available
Description	Ribonuclease H2 subunit B (RNase H2 subunit B) (Ribonuclease HI subunit B) (Deleted in lymphocytic leukemia 8 homolog).

ARHG7_HUMAN
θ value	θ > 10 (rank : 33)	NC score	0.097815 (rank : 30)
Query Neighborhood Hits	32	Target Neighborhood Hits	347	Shared Neighborhood Hits	21
SwissProt Accessions	Q14155, Q6P9G3, Q6PII2, Q86W63, Q8N3M1	Gene names	ARHGEF7, COOL1, KIAA0142, P85SPR, PAK3BP, PIXB
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (COOL-1) (p85).

GA2L2_HUMAN
θ value	θ > 10 (rank : 34)	NC score	0.052973 (rank : 35)
Query Neighborhood Hits	32	Target Neighborhood Hits	175	Shared Neighborhood Hits	11
SwissProt Accessions	Q8NHY3, Q8NHY4	Gene names	GAS2L2, GAR17
Domain Architecture	No domain graphic available
Description	GAS2-like protein 2 (Growth arrest-specific 2-like 2) (GAS2-related protein on chromosome 17) (GAR17 protein).

IQGA3_HUMAN
θ value	θ > 10 (rank : 35)	NC score	0.074754 (rank : 32)
Query Neighborhood Hits	32	Target Neighborhood Hits	125	Shared Neighborhood Hits	18
SwissProt Accessions	Q86VI3	Gene names	IQGAP3
Domain Architecture
Description	Ras GTPase-activating-like protein IQGAP3.

PKHG1_HUMAN
θ value	θ > 10 (rank : 36)	NC score	0.055902 (rank : 34)
Query Neighborhood Hits	32	Target Neighborhood Hits	174	Shared Neighborhood Hits	8
SwissProt Accessions	Q9ULL1, Q5T1F2	Gene names	PLEKHG1, KIAA1209
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family G member 1.

Hits sorted by NC score

TAGL_HUMAN
NC score	0.999962 (rank : 1)	θ value	1.58745e-113 (rank : 1)
Query Neighborhood Hits	32	Target Neighborhood Hits	32	Shared Neighborhood Hits	32
SwissProt Accessions	Q01995, O15542	Gene names	TAGLN, SM22, WS3-10
Domain Architecture
Description	Transgelin (Smooth muscle protein 22-alpha) (SM22-alpha) (WS3-10) (22 kDa actin-binding protein).

TAGL_MOUSE
NC score	0.999651 (rank : 2)	θ value	4.32305e-111 (rank : 2)
Query Neighborhood Hits	32	Target Neighborhood Hits	33	Shared Neighborhood Hits	32
SwissProt Accessions	P37804, Q545W0	Gene names	Tagln, Sm22, Sm22a
Domain Architecture
Description	Transgelin (Smooth muscle protein 22-alpha) (SM22-alpha) (Actin- associated protein p27).

TAGL3_HUMAN
NC score	0.991087 (rank : 3)	θ value	2.92676e-75 (rank : 3)
Query Neighborhood Hits	32	Target Neighborhood Hits	33	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UI15, Q96A74	Gene names	TAGLN3, NP25
Domain Architecture
Description	Transgelin-3 (Neuronal protein NP25) (Neuronal protein 22) (NP22).

TAGL3_MOUSE
NC score	0.990983 (rank : 4)	θ value	4.99229e-75 (rank : 4)
Query Neighborhood Hits	32	Target Neighborhood Hits	33	Shared Neighborhood Hits	27
SwissProt Accessions	Q9R1Q8	Gene names	Tagln3, Np25
Domain Architecture
Description	Transgelin-3 (Neuronal protein NP25).

TAGL2_HUMAN
NC score	0.988329 (rank : 5)	θ value	1.04096e-72 (rank : 5)
Query Neighborhood Hits	32	Target Neighborhood Hits	35	Shared Neighborhood Hits	28
SwissProt Accessions	P37802, Q5JRQ6, Q5JRQ7, Q9BUH5, Q9H4P0	Gene names	TAGLN2, KIAA0120
Domain Architecture
Description	Transgelin-2 (SM22-alpha homolog).

TAGL2_MOUSE
NC score	0.987394 (rank : 6)	θ value	2.17053e-70 (rank : 6)
Query Neighborhood Hits	32	Target Neighborhood Hits	42	Shared Neighborhood Hits	30
SwissProt Accessions	Q9WVA4	Gene names	Tagln2
Domain Architecture
Description	Transgelin-2.

CNN1_MOUSE
NC score	0.893605 (rank : 7)	θ value	8.06329e-33 (rank : 10)
Query Neighborhood Hits	32	Target Neighborhood Hits	37	Shared Neighborhood Hits	29
SwissProt Accessions	Q08091	Gene names	Cnn1
Domain Architecture
Description	Calponin-1 (Calponin H1, smooth muscle) (Basic calponin).

CNN1_HUMAN
NC score	0.892756 (rank : 8)	θ value	8.06329e-33 (rank : 9)
Query Neighborhood Hits	32	Target Neighborhood Hits	38	Shared Neighborhood Hits	29
SwissProt Accessions	P51911, O00638, Q15416, Q8IY93, Q99438	Gene names	CNN1
Domain Architecture
Description	Calponin-1 (Calponin H1, smooth muscle) (Basic calponin).

CNN3_MOUSE
NC score	0.890392 (rank : 9)	θ value	1.73584e-35 (rank : 7)
Query Neighborhood Hits	32	Target Neighborhood Hits	45	Shared Neighborhood Hits	31
SwissProt Accessions	Q9DAW9, Q3TW23	Gene names	Cnn3
Domain Architecture	No domain graphic available
Description	Calponin-3 (Calponin, acidic isoform).

CNN3_HUMAN
NC score	0.890182 (rank : 10)	θ value	2.26708e-35 (rank : 8)
Query Neighborhood Hits	32	Target Neighborhood Hits	43	Shared Neighborhood Hits	31
SwissProt Accessions	Q15417	Gene names	CNN3
Domain Architecture
Description	Calponin-3 (Calponin, acidic isoform).

CNN2_MOUSE
NC score	0.883676 (rank : 11)	θ value	2.42779e-29 (rank : 11)
Query Neighborhood Hits	32	Target Neighborhood Hits	39	Shared Neighborhood Hits	31
SwissProt Accessions	Q08093	Gene names	Cnn2
Domain Architecture
Description	Calponin-2 (Calponin H2, smooth muscle) (Neutral calponin).

CNN2_HUMAN
NC score	0.883077 (rank : 12)	θ value	9.2256e-29 (rank : 12)
Query Neighborhood Hits	32	Target Neighborhood Hits	37	Shared Neighborhood Hits	29
SwissProt Accessions	Q99439, Q92578	Gene names	CNN2
Domain Architecture
Description	Calponin-2 (Calponin H2, smooth muscle) (Neutral calponin).

LMO7_HUMAN
NC score	0.329590 (rank : 13)	θ value	0.0961366 (rank : 24)
Query Neighborhood Hits	32	Target Neighborhood Hits	507	Shared Neighborhood Hits	29
SwissProt Accessions	Q8WWI1, O15462, O95346, Q9UKC1, Q9UQM5, Q9Y6A7	Gene names	LMO7, FBX20, FBXO20, KIAA0858
Domain Architecture
Description	LIM domain only protein 7 (LOMP) (F-box only protein 20).

VAV_MOUSE
NC score	0.221492 (rank : 14)	θ value	2.44474e-05 (rank : 13)
Query Neighborhood Hits	32	Target Neighborhood Hits	430	Shared Neighborhood Hits	31
SwissProt Accessions	P27870, Q8BTV7	Gene names	Vav1, Vav
Domain Architecture
Description	Proto-oncogene vav (p95vav).

VAV3_MOUSE
NC score	0.220660 (rank : 15)	θ value	0.000270298 (rank : 15)
Query Neighborhood Hits	32	Target Neighborhood Hits	404	Shared Neighborhood Hits	29
SwissProt Accessions	Q9R0C8, Q7TS85	Gene names	Vav3
Domain Architecture
Description	Protein vav-3.

VAV_HUMAN
NC score	0.213892 (rank : 16)	θ value	4.1701e-05 (rank : 14)
Query Neighborhood Hits	32	Target Neighborhood Hits	452	Shared Neighborhood Hits	31
SwissProt Accessions	P15498, Q15860	Gene names	VAV1, VAV
Domain Architecture
Description	Proto-oncogene vav.

VAV3_HUMAN
NC score	0.207689 (rank : 17)	θ value	0.00134147 (rank : 16)
Query Neighborhood Hits	32	Target Neighborhood Hits	398	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UKW4, O95230, Q9Y5X8	Gene names	VAV3
Domain Architecture
Description	Protein vav-3.

VAV2_HUMAN
NC score	0.204491 (rank : 18)	θ value	0.00298849 (rank : 17)
Query Neighborhood Hits	32	Target Neighborhood Hits	453	Shared Neighborhood Hits	31
SwissProt Accessions	P52735	Gene names	VAV2
Domain Architecture
Description	Protein vav-2.

VAV2_MOUSE
NC score	0.203707 (rank : 19)	θ value	0.00869519 (rank : 21)
Query Neighborhood Hits	32	Target Neighborhood Hits	456	Shared Neighborhood Hits	31
SwissProt Accessions	Q60992	Gene names	Vav2
Domain Architecture
Description	Protein vav-2.

ARHG6_MOUSE
NC score	0.197948 (rank : 20)	θ value	0.00665767 (rank : 18)
Query Neighborhood Hits	32	Target Neighborhood Hits	394	Shared Neighborhood Hits	29
SwissProt Accessions	Q8K4I3, Q8C9V4	Gene names	Arhgef6
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6).

LRCH1_HUMAN
NC score	0.190746 (rank : 21)	θ value	0.00665767 (rank : 19)
Query Neighborhood Hits	32	Target Neighborhood Hits	266	Shared Neighborhood Hits	29
SwissProt Accessions	Q9Y2L9, Q7Z5F6, Q7Z5F7	Gene names	LRCH1, CHDC1, KIAA1016
Domain Architecture
Description	Leucine-rich repeats and calponin homology domain-containing protein 1 (Calponin homology domain-containing protein 1) (Neuronal protein 81) (NP81).

LRCH1_MOUSE
NC score	0.188242 (rank : 22)	θ value	0.00869519 (rank : 20)
Query Neighborhood Hits	32	Target Neighborhood Hits	264	Shared Neighborhood Hits	29
SwissProt Accessions	P62046	Gene names	Lrch1, Chdc1, Kiaa1016
Domain Architecture
Description	Leucine-rich repeats and calponin homology domain-containing protein 1 (Calponin homology domain-containing protein 1).

ARHG6_HUMAN
NC score	0.178356 (rank : 23)	θ value	0.125558 (rank : 26)
Query Neighborhood Hits	32	Target Neighborhood Hits	376	Shared Neighborhood Hits	29
SwissProt Accessions	Q15052, Q15396, Q5JQ66, Q86XH0	Gene names	ARHGEF6, COOL2, KIAA0006, PIXA
Domain Architecture
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6) (PAK-interacting exchange factor alpha) (Alpha-Pix) (COOL-2).

LRCH3_HUMAN
NC score	0.165616 (rank : 24)	θ value	0.0330416 (rank : 22)
Query Neighborhood Hits	32	Target Neighborhood Hits	270	Shared Neighborhood Hits	29
SwissProt Accessions	Q96II8, Q96FP9, Q9NT52	Gene names	LRCH3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and calponin homology domain-containing protein 3 precursor.

LRCH2_HUMAN
NC score	0.155382 (rank : 25)	θ value	0.365318 (rank : 27)
Query Neighborhood Hits	32	Target Neighborhood Hits	315	Shared Neighborhood Hits	28
SwissProt Accessions	Q5VUJ6, Q9HA88, Q9P233	Gene names	LRCH2, KIAA1495
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and calponin homology domain-containing protein 2.

LRCH3_MOUSE
NC score	0.154939 (rank : 26)	θ value	0.365318 (rank : 29)
Query Neighborhood Hits	32	Target Neighborhood Hits	257	Shared Neighborhood Hits	29
SwissProt Accessions	Q8BVU0, Q3U222, Q3UZ74	Gene names	Lrch3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and calponin homology domain-containing protein 3 precursor.

LRCH2_MOUSE
NC score	0.153518 (rank : 27)	θ value	0.365318 (rank : 28)
Query Neighborhood Hits	32	Target Neighborhood Hits	287	Shared Neighborhood Hits	28
SwissProt Accessions	Q3UMG5, Q7TNP9, Q80TC9	Gene names	Lrch2, Kiaa1495
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and calponin homology domain-containing protein 2.

LRCH4_MOUSE
NC score	0.148827 (rank : 28)	θ value	0.0563607 (rank : 23)
Query Neighborhood Hits	32	Target Neighborhood Hits	302	Shared Neighborhood Hits	27
SwissProt Accessions	Q921G6	Gene names	Lrch4
Domain Architecture
Description	Leucine-rich repeats and calponin homology domain-containing protein 4.

LRCH4_HUMAN
NC score	0.135429 (rank : 29)	θ value	0.0961366 (rank : 25)
Query Neighborhood Hits	32	Target Neighborhood Hits	305	Shared Neighborhood Hits	25
SwissProt Accessions	O75427, Q8WV85, Q96ID0	Gene names	LRCH4, LRN, LRRN4
Domain Architecture
Description	Leucine-rich repeats and calponin homology domain-containing protein 4 (Leucine-rich neuronal protein).

ARHG7_HUMAN
NC score	0.097815 (rank : 30)	θ value	θ > 10 (rank : 33)
Query Neighborhood Hits	32	Target Neighborhood Hits	347	Shared Neighborhood Hits	21
SwissProt Accessions	Q14155, Q6P9G3, Q6PII2, Q86W63, Q8N3M1	Gene names	ARHGEF7, COOL1, KIAA0142, P85SPR, PAK3BP, PIXB
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (COOL-1) (p85).

IQGA1_MOUSE
NC score	0.075104 (rank : 31)	θ value	0.62314 (rank : 31)
Query Neighborhood Hits	32	Target Neighborhood Hits	219	Shared Neighborhood Hits	13
SwissProt Accessions	Q9JKF1	Gene names	Iqgap1
Domain Architecture
Description	Ras GTPase-activating-like protein IQGAP1.

IQGA3_HUMAN
NC score	0.074754 (rank : 32)	θ value	θ > 10 (rank : 35)
Query Neighborhood Hits	32	Target Neighborhood Hits	125	Shared Neighborhood Hits	18
SwissProt Accessions	Q86VI3	Gene names	IQGAP3
Domain Architecture
Description	Ras GTPase-activating-like protein IQGAP3.

IQGA1_HUMAN
NC score	0.074058 (rank : 33)	θ value	0.62314 (rank : 30)
Query Neighborhood Hits	32	Target Neighborhood Hits	250	Shared Neighborhood Hits	13
SwissProt Accessions	P46940	Gene names	IQGAP1, KIAA0051
Domain Architecture
Description	Ras GTPase-activating-like protein IQGAP1 (p195).

PKHG1_HUMAN
NC score	0.055902 (rank : 34)	θ value	θ > 10 (rank : 36)
Query Neighborhood Hits	32	Target Neighborhood Hits	174	Shared Neighborhood Hits	8
SwissProt Accessions	Q9ULL1, Q5T1F2	Gene names	PLEKHG1, KIAA1209
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family G member 1.

GA2L2_HUMAN
NC score	0.052973 (rank : 35)	θ value	θ > 10 (rank : 34)
Query Neighborhood Hits	32	Target Neighborhood Hits	175	Shared Neighborhood Hits	11
SwissProt Accessions	Q8NHY3, Q8NHY4	Gene names	GAS2L2, GAR17
Domain Architecture	No domain graphic available
Description	GAS2-like protein 2 (Growth arrest-specific 2-like 2) (GAS2-related protein on chromosome 17) (GAR17 protein).

RNH2B_MOUSE
NC score	0.036601 (rank : 36)	θ value	1.38821 (rank : 32)
Query Neighborhood Hits	32	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	Q80ZV0, Q9D014	Gene names	Dleu8, Rnaseh2b
Domain Architecture	No domain graphic available
Description	Ribonuclease H2 subunit B (RNase H2 subunit B) (Ribonuclease HI subunit B) (Deleted in lymphocytic leukemia 8 homolog).