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Network neighborhood for query Sequence : SYS_MOUSE

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SYS_MOUSE
SwissProt Accessions	P26638	Gene names	Sars, Sars1, Sers
Domain Architecture
Description	Seryl-tRNA synthetase (EC 6.1.1.11) (Serine--tRNA ligase) (SerRS).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SYS_HUMAN
θ value	0 (rank : 1)	NC score	0.997352 (rank : 2)
Query Neighborhood Hits	13	Target Neighborhood Hits	17	Shared Neighborhood Hits	10
SwissProt Accessions	P49591, Q9NSE3	Gene names	SARS, SERS
Domain Architecture
Description	Seryl-tRNA synthetase (EC 6.1.1.11) (Serine--tRNA ligase) (SerRS).

SYS_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	13	Target Neighborhood Hits	13	Shared Neighborhood Hits	13
SwissProt Accessions	P26638	Gene names	Sars, Sars1, Sers
Domain Architecture
Description	Seryl-tRNA synthetase (EC 6.1.1.11) (Serine--tRNA ligase) (SerRS).

SYSM_MOUSE
θ value	6.58091e-43 (rank : 3)	NC score	0.806066 (rank : 3)
Query Neighborhood Hits	13	Target Neighborhood Hits	19	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JJL8, Q9CWP1	Gene names	Sars2, Sarsm
Domain Architecture
Description	Seryl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.11) (Serine-- tRNA ligase) (SerRSmt).

SYSM_HUMAN
θ value	3.26607e-42 (rank : 4)	NC score	0.803762 (rank : 4)
Query Neighborhood Hits	13	Target Neighborhood Hits	32	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NP81, Q9BVP3	Gene names	SARS2, SARSM
Domain Architecture
Description	Seryl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.11) (Serine-- tRNA ligase) (SerRSmt).

PAPS1_MOUSE
θ value	0.365318 (rank : 5)	NC score	0.049530 (rank : 7)
Query Neighborhood Hits	13	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	Q60967	Gene names	Papss1, Asapk, Atpsk1, Papss
Domain Architecture
Description	Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthetase 1 (PAPS synthetase 1) (PAPSS 1) (Sulfurylase kinase 1) (SK1) (SK 1) [Includes: Sulfate adenylyltransferase (EC 2.7.7.4) (Sulfate adenylate transferase) (SAT) (ATP-sulfurylase); Adenylyl-sulfate kinase (EC 2.7.1.25) (Adenylylsulfate 3'-phosphotransferase) (APS kinase) (Adenosine-5'-phosphosulfate 3'-phosphotransferase) (3'- phosphoadenosine-5'-phosphosulfate synthetase)].

NBN_HUMAN
θ value	0.62314 (rank : 6)	NC score	0.053551 (rank : 6)
Query Neighborhood Hits	13	Target Neighborhood Hits	226	Shared Neighborhood Hits	4
SwissProt Accessions	O60934, O60672, Q32NF7, Q53FM6, Q63HR6, Q7LDM2	Gene names	NBN, NBS, NBS1, P95
Domain Architecture	No domain graphic available
Description	Nibrin (Nijmegen breakage syndrome protein 1) (Cell cycle regulatory protein p95).

DHX29_HUMAN
θ value	0.813845 (rank : 7)	NC score	0.029118 (rank : 11)
Query Neighborhood Hits	13	Target Neighborhood Hits	144	Shared Neighborhood Hits	4
SwissProt Accessions	Q7Z478, O75549, Q63HN0, Q63HN3, Q8IWW2, Q8N3A1, Q9UMH2	Gene names	DHX29
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX29 (EC 3.6.1.-) (DEAH box protein 29) (Nucleic acid helicase DDXx).

NSD1_HUMAN
θ value	1.06291 (rank : 8)	NC score	0.030616 (rank : 10)
Query Neighborhood Hits	13	Target Neighborhood Hits	427	Shared Neighborhood Hits	3
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

PAPS1_HUMAN
θ value	1.06291 (rank : 9)	NC score	0.045623 (rank : 8)
Query Neighborhood Hits	13	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	O43252, O43841, O75332, Q96FB1, Q96TF4, Q9P1P9, Q9UE98	Gene names	PAPSS1, ATPSK1, PAPSS
Domain Architecture
Description	Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthetase 1 (PAPS synthetase 1) (PAPSS 1) (Sulfurylase kinase 1) (SK1) (SK 1) [Includes: Sulfate adenylyltransferase (EC 2.7.7.4) (Sulfate adenylate transferase) (SAT) (ATP-sulfurylase); Adenylyl-sulfate kinase (EC 2.7.1.25) (Adenylylsulfate 3'-phosphotransferase) (APS kinase) (Adenosine-5'-phosphosulfate 3'-phosphotransferase) (3'- phosphoadenosine-5'-phosphosulfate synthetase)].

FAK2_MOUSE
θ value	1.38821 (rank : 10)	NC score	0.006058 (rank : 13)
Query Neighborhood Hits	13	Target Neighborhood Hits	851	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QVP9	Gene names	Ptk2b, Fak2, Pyk2, Raftk
Domain Architecture	No domain graphic available
Description	Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) (Related adhesion focal tyrosine kinase) (RAFTK).

NBN_MOUSE
θ value	1.38821 (rank : 11)	NC score	0.058569 (rank : 5)
Query Neighborhood Hits	13	Target Neighborhood Hits	125	Shared Neighborhood Hits	4
SwissProt Accessions	Q9R207, O88981, Q3UY57, Q811I6, Q8CCY0, Q9R1X1	Gene names	Nbn, Nbs1
Domain Architecture	No domain graphic available
Description	Nibrin (Nijmegen breakage syndrome protein 1 homolog) (Cell cycle regulatory protein p95).

ALO17_HUMAN
θ value	2.36792 (rank : 12)	NC score	0.043484 (rank : 9)
Query Neighborhood Hits	13	Target Neighborhood Hits	317	Shared Neighborhood Hits	3
SwissProt Accessions	Q9HCF4, Q69YK7, Q8IWF4, Q8IZX1, Q8IZX2, Q8N406	Gene names	KIAA1618, ALO17
Domain Architecture	No domain graphic available
Description	Protein ALO17 (ALK lymphoma oligomerization partner on chromosome 17).

FMR1_HUMAN
θ value	8.99809 (rank : 13)	NC score	0.017637 (rank : 12)
Query Neighborhood Hits	13	Target Neighborhood Hits	45	Shared Neighborhood Hits	3
SwissProt Accessions	Q06787, Q16578, Q99054	Gene names	FMR1
Domain Architecture
Description	Fragile X mental retardation 1 protein (Protein FMR-1) (FMRP).

Hits sorted by NC score

SYS_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	13	Target Neighborhood Hits	13	Shared Neighborhood Hits	13
SwissProt Accessions	P26638	Gene names	Sars, Sars1, Sers
Domain Architecture
Description	Seryl-tRNA synthetase (EC 6.1.1.11) (Serine--tRNA ligase) (SerRS).

SYS_HUMAN
NC score	0.997352 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	13	Target Neighborhood Hits	17	Shared Neighborhood Hits	10
SwissProt Accessions	P49591, Q9NSE3	Gene names	SARS, SERS
Domain Architecture
Description	Seryl-tRNA synthetase (EC 6.1.1.11) (Serine--tRNA ligase) (SerRS).

SYSM_MOUSE
NC score	0.806066 (rank : 3)	θ value	6.58091e-43 (rank : 3)
Query Neighborhood Hits	13	Target Neighborhood Hits	19	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JJL8, Q9CWP1	Gene names	Sars2, Sarsm
Domain Architecture
Description	Seryl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.11) (Serine-- tRNA ligase) (SerRSmt).

SYSM_HUMAN
NC score	0.803762 (rank : 4)	θ value	3.26607e-42 (rank : 4)
Query Neighborhood Hits	13	Target Neighborhood Hits	32	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NP81, Q9BVP3	Gene names	SARS2, SARSM
Domain Architecture
Description	Seryl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.11) (Serine-- tRNA ligase) (SerRSmt).

NBN_MOUSE
NC score	0.058569 (rank : 5)	θ value	1.38821 (rank : 11)
Query Neighborhood Hits	13	Target Neighborhood Hits	125	Shared Neighborhood Hits	4
SwissProt Accessions	Q9R207, O88981, Q3UY57, Q811I6, Q8CCY0, Q9R1X1	Gene names	Nbn, Nbs1
Domain Architecture	No domain graphic available
Description	Nibrin (Nijmegen breakage syndrome protein 1 homolog) (Cell cycle regulatory protein p95).

NBN_HUMAN
NC score	0.053551 (rank : 6)	θ value	0.62314 (rank : 6)
Query Neighborhood Hits	13	Target Neighborhood Hits	226	Shared Neighborhood Hits	4
SwissProt Accessions	O60934, O60672, Q32NF7, Q53FM6, Q63HR6, Q7LDM2	Gene names	NBN, NBS, NBS1, P95
Domain Architecture	No domain graphic available
Description	Nibrin (Nijmegen breakage syndrome protein 1) (Cell cycle regulatory protein p95).

PAPS1_MOUSE
NC score	0.049530 (rank : 7)	θ value	0.365318 (rank : 5)
Query Neighborhood Hits	13	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	Q60967	Gene names	Papss1, Asapk, Atpsk1, Papss
Domain Architecture
Description	Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthetase 1 (PAPS synthetase 1) (PAPSS 1) (Sulfurylase kinase 1) (SK1) (SK 1) [Includes: Sulfate adenylyltransferase (EC 2.7.7.4) (Sulfate adenylate transferase) (SAT) (ATP-sulfurylase); Adenylyl-sulfate kinase (EC 2.7.1.25) (Adenylylsulfate 3'-phosphotransferase) (APS kinase) (Adenosine-5'-phosphosulfate 3'-phosphotransferase) (3'- phosphoadenosine-5'-phosphosulfate synthetase)].

PAPS1_HUMAN
NC score	0.045623 (rank : 8)	θ value	1.06291 (rank : 9)
Query Neighborhood Hits	13	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	O43252, O43841, O75332, Q96FB1, Q96TF4, Q9P1P9, Q9UE98	Gene names	PAPSS1, ATPSK1, PAPSS
Domain Architecture
Description	Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthetase 1 (PAPS synthetase 1) (PAPSS 1) (Sulfurylase kinase 1) (SK1) (SK 1) [Includes: Sulfate adenylyltransferase (EC 2.7.7.4) (Sulfate adenylate transferase) (SAT) (ATP-sulfurylase); Adenylyl-sulfate kinase (EC 2.7.1.25) (Adenylylsulfate 3'-phosphotransferase) (APS kinase) (Adenosine-5'-phosphosulfate 3'-phosphotransferase) (3'- phosphoadenosine-5'-phosphosulfate synthetase)].

ALO17_HUMAN
NC score	0.043484 (rank : 9)	θ value	2.36792 (rank : 12)
Query Neighborhood Hits	13	Target Neighborhood Hits	317	Shared Neighborhood Hits	3
SwissProt Accessions	Q9HCF4, Q69YK7, Q8IWF4, Q8IZX1, Q8IZX2, Q8N406	Gene names	KIAA1618, ALO17
Domain Architecture	No domain graphic available
Description	Protein ALO17 (ALK lymphoma oligomerization partner on chromosome 17).

NSD1_HUMAN
NC score	0.030616 (rank : 10)	θ value	1.06291 (rank : 8)
Query Neighborhood Hits	13	Target Neighborhood Hits	427	Shared Neighborhood Hits	3
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

DHX29_HUMAN
NC score	0.029118 (rank : 11)	θ value	0.813845 (rank : 7)
Query Neighborhood Hits	13	Target Neighborhood Hits	144	Shared Neighborhood Hits	4
SwissProt Accessions	Q7Z478, O75549, Q63HN0, Q63HN3, Q8IWW2, Q8N3A1, Q9UMH2	Gene names	DHX29
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX29 (EC 3.6.1.-) (DEAH box protein 29) (Nucleic acid helicase DDXx).

FMR1_HUMAN
NC score	0.017637 (rank : 12)	θ value	8.99809 (rank : 13)
Query Neighborhood Hits	13	Target Neighborhood Hits	45	Shared Neighborhood Hits	3
SwissProt Accessions	Q06787, Q16578, Q99054	Gene names	FMR1
Domain Architecture
Description	Fragile X mental retardation 1 protein (Protein FMR-1) (FMRP).

FAK2_MOUSE
NC score	0.006058 (rank : 13)	θ value	1.38821 (rank : 10)
Query Neighborhood Hits	13	Target Neighborhood Hits	851	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QVP9	Gene names	Ptk2b, Fak2, Pyk2, Raftk
Domain Architecture	No domain graphic available
Description	Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) (Related adhesion focal tyrosine kinase) (RAFTK).