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Network neighborhood for query Sequence : SYK_HUMAN

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SYK_HUMAN
SwissProt Accessions	Q15046, O14946, Q96J25	Gene names	KARS, KIAA0070
Domain Architecture
Description	Lysyl-tRNA synthetase (EC 6.1.1.6) (Lysine--tRNA ligase) (LysRS).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SYK_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	19	Target Neighborhood Hits	19	Shared Neighborhood Hits	19
SwissProt Accessions	Q15046, O14946, Q96J25	Gene names	KARS, KIAA0070
Domain Architecture
Description	Lysyl-tRNA synthetase (EC 6.1.1.6) (Lysine--tRNA ligase) (LysRS).

SYK_MOUSE
θ value	0 (rank : 2)	NC score	0.997356 (rank : 2)
Query Neighborhood Hits	19	Target Neighborhood Hits	20	Shared Neighborhood Hits	12
SwissProt Accessions	Q99MN1	Gene names	Kars
Domain Architecture
Description	Lysyl-tRNA synthetase (EC 6.1.1.6) (Lysine--tRNA ligase) (LysRS).

SYDC_HUMAN
θ value	3.40345e-15 (rank : 3)	NC score	0.574869 (rank : 3)
Query Neighborhood Hits	19	Target Neighborhood Hits	13	Shared Neighborhood Hits	10
SwissProt Accessions	P14868, Q2TNI3, Q32Q69, Q53HV4, Q53YC5, Q9BW52	Gene names	DARS, PIG40
Domain Architecture
Description	Aspartyl-tRNA synthetase, cytoplasmic (EC 6.1.1.12) (Aspartate--tRNA ligase) (AspRS) (Cell proliferation-inducing gene 40 protein).

SYDC_MOUSE
θ value	8.38298e-14 (rank : 4)	NC score	0.564946 (rank : 4)
Query Neighborhood Hits	19	Target Neighborhood Hits	15	Shared Neighborhood Hits	10
SwissProt Accessions	Q922B2	Gene names	Dars
Domain Architecture
Description	Aspartyl-tRNA synthetase, cytoplasmic (EC 6.1.1.12) (Aspartate--tRNA ligase) (AspRS).

SYDM_HUMAN
θ value	2.43908e-13 (rank : 5)	NC score	0.543335 (rank : 5)
Query Neighborhood Hits	19	Target Neighborhood Hits	18	Shared Neighborhood Hits	10
SwissProt Accessions	Q6PI48	Gene names	DARS2
Domain Architecture	No domain graphic available
Description	Aspartyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.12) (Aspartate--tRNA ligase) (AspRS).

SYDM_MOUSE
θ value	5.43371e-13 (rank : 6)	NC score	0.536528 (rank : 6)
Query Neighborhood Hits	19	Target Neighborhood Hits	16	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BIP0, Q5FWV4	Gene names	Dars2
Domain Architecture	No domain graphic available
Description	Aspartyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.12) (Aspartate--tRNA ligase) (AspRS).

SYNC_MOUSE
θ value	6.43352e-06 (rank : 7)	NC score	0.397224 (rank : 7)
Query Neighborhood Hits	19	Target Neighborhood Hits	44	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BP47, Q9CRY5	Gene names	Nars
Domain Architecture
Description	Asparaginyl-tRNA synthetase, cytoplasmic (EC 6.1.1.22) (Asparagine-- tRNA ligase) (AsnRS).

SYNM_HUMAN
θ value	9.29e-05 (rank : 8)	NC score	0.373707 (rank : 9)
Query Neighborhood Hits	19	Target Neighborhood Hits	15	Shared Neighborhood Hits	10
SwissProt Accessions	Q96I59	Gene names	NARS2
Domain Architecture	No domain graphic available
Description	Probable asparaginyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.22) (Asparagine--tRNA ligase) (AsnRS).

SYNM_MOUSE
θ value	0.000158464 (rank : 9)	NC score	0.385285 (rank : 8)
Query Neighborhood Hits	19	Target Neighborhood Hits	14	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BGV0	Gene names	Nars2
Domain Architecture	No domain graphic available
Description	Probable asparaginyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.22) (Asparagine--tRNA ligase) (AsnRS).

SYNC_HUMAN
θ value	0.00035302 (rank : 10)	NC score	0.361189 (rank : 10)
Query Neighborhood Hits	19	Target Neighborhood Hits	47	Shared Neighborhood Hits	10
SwissProt Accessions	O43776	Gene names	NARS, ASNS
Domain Architecture
Description	Asparaginyl-tRNA synthetase, cytoplasmic (EC 6.1.1.22) (Asparagine-- tRNA ligase) (AsnRS).

RUFY3_MOUSE
θ value	1.06291 (rank : 11)	NC score	0.016193 (rank : 13)
Query Neighborhood Hits	19	Target Neighborhood Hits	579	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D394, Q3U348, Q3UF96, Q6PE64, Q8VD10	Gene names	Rufy3, D5Bwg0860e, Ripx
Domain Architecture	No domain graphic available
Description	Protein RUFY3 (Rap2-interacting protein x) (RIPx).

SASH1_MOUSE
θ value	1.81305 (rank : 12)	NC score	0.027978 (rank : 11)
Query Neighborhood Hits	19	Target Neighborhood Hits	263	Shared Neighborhood Hits	3
SwissProt Accessions	P59808	Gene names	Sash1
Domain Architecture
Description	SAM and SH3 domain-containing protein 1.

HS70L_HUMAN
θ value	2.36792 (rank : 13)	NC score	0.010211 (rank : 16)
Query Neighborhood Hits	19	Target Neighborhood Hits	50	Shared Neighborhood Hits	2
SwissProt Accessions	P34931, O75634, Q2HXR3, Q8NE72, Q96QC9, Q9UQM1	Gene names	HSPA1L
Domain Architecture
Description	Heat shock 70 kDa protein 1L (Heat shock 70 kDa protein 1-like) (Heat shock 70 kDa protein 1-Hom) (HSP70-Hom).

ARHGA_MOUSE
θ value	4.03905 (rank : 14)	NC score	0.013808 (rank : 15)
Query Neighborhood Hits	19	Target Neighborhood Hits	125	Shared Neighborhood Hits	2
SwissProt Accessions	Q8C033, Q5DU38, Q80VH8, Q8BW76, Q922S7	Gene names	Arhgef10, Kiaa0294
Domain Architecture
Description	Rho guanine nucleotide exchange factor 10.

FUT9_MOUSE
θ value	5.27518 (rank : 15)	NC score	0.024733 (rank : 12)
Query Neighborhood Hits	19	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	O88819, Q3TQ63	Gene names	Fut9
Domain Architecture	No domain graphic available
Description	Alpha-(1,3)-fucosyltransferase (EC 2.4.1.-) (Galactoside 3-L- fucosyltransferase) (Fucosyltransferase 9) (FUCT-IX).

DSC3_MOUSE
θ value	6.88961 (rank : 16)	NC score	0.003607 (rank : 17)
Query Neighborhood Hits	19	Target Neighborhood Hits	154	Shared Neighborhood Hits	2
SwissProt Accessions	P55850, O55110, O55122	Gene names	Dsc3
Domain Architecture
Description	Desmocollin-3 precursor.

CABYR_MOUSE
θ value	8.99809 (rank : 17)	NC score	0.015008 (rank : 14)
Query Neighborhood Hits	19	Target Neighborhood Hits	80	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D424, Q91Y41, Q91Y42	Gene names	Cabyr, Cbp86
Domain Architecture	No domain graphic available
Description	Calcium-binding tyrosine phosphorylation-regulated protein (Calcium- binding protein 86) (Testis-specific calcium-binding protein CBP86).

ZBT7A_HUMAN
θ value	8.99809 (rank : 18)	NC score	0.000658 (rank : 18)
Query Neighborhood Hits	19	Target Neighborhood Hits	823	Shared Neighborhood Hits	3
SwissProt Accessions	O95365, O00456	Gene names	ZBTB7A, FBI1, LRF, ZBTB7
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 7A (Leukemia/lymphoma- related factor) (Factor that binds to inducer of short transcripts protein 1) (Factor binding IST protein 1) (FBI-1) (HIV-1 1st-binding protein 1) (TTF-I-interacting peptide 21) (TIP21).

ZBT7A_MOUSE
θ value	8.99809 (rank : 19)	NC score	0.000643 (rank : 19)
Query Neighborhood Hits	19	Target Neighborhood Hits	795	Shared Neighborhood Hits	3
SwissProt Accessions	O88939, Q9CRJ0	Gene names	Zbtb7a, Lrf, Zbtb7
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 7A (Leukemia/lymphoma- related factor).

Hits sorted by NC score

SYK_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	19	Target Neighborhood Hits	19	Shared Neighborhood Hits	19
SwissProt Accessions	Q15046, O14946, Q96J25	Gene names	KARS, KIAA0070
Domain Architecture
Description	Lysyl-tRNA synthetase (EC 6.1.1.6) (Lysine--tRNA ligase) (LysRS).

SYK_MOUSE
NC score	0.997356 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	19	Target Neighborhood Hits	20	Shared Neighborhood Hits	12
SwissProt Accessions	Q99MN1	Gene names	Kars
Domain Architecture
Description	Lysyl-tRNA synthetase (EC 6.1.1.6) (Lysine--tRNA ligase) (LysRS).

SYDC_HUMAN
NC score	0.574869 (rank : 3)	θ value	3.40345e-15 (rank : 3)
Query Neighborhood Hits	19	Target Neighborhood Hits	13	Shared Neighborhood Hits	10
SwissProt Accessions	P14868, Q2TNI3, Q32Q69, Q53HV4, Q53YC5, Q9BW52	Gene names	DARS, PIG40
Domain Architecture
Description	Aspartyl-tRNA synthetase, cytoplasmic (EC 6.1.1.12) (Aspartate--tRNA ligase) (AspRS) (Cell proliferation-inducing gene 40 protein).

SYDC_MOUSE
NC score	0.564946 (rank : 4)	θ value	8.38298e-14 (rank : 4)
Query Neighborhood Hits	19	Target Neighborhood Hits	15	Shared Neighborhood Hits	10
SwissProt Accessions	Q922B2	Gene names	Dars
Domain Architecture
Description	Aspartyl-tRNA synthetase, cytoplasmic (EC 6.1.1.12) (Aspartate--tRNA ligase) (AspRS).

SYDM_HUMAN
NC score	0.543335 (rank : 5)	θ value	2.43908e-13 (rank : 5)
Query Neighborhood Hits	19	Target Neighborhood Hits	18	Shared Neighborhood Hits	10
SwissProt Accessions	Q6PI48	Gene names	DARS2
Domain Architecture	No domain graphic available
Description	Aspartyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.12) (Aspartate--tRNA ligase) (AspRS).

SYDM_MOUSE
NC score	0.536528 (rank : 6)	θ value	5.43371e-13 (rank : 6)
Query Neighborhood Hits	19	Target Neighborhood Hits	16	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BIP0, Q5FWV4	Gene names	Dars2
Domain Architecture	No domain graphic available
Description	Aspartyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.12) (Aspartate--tRNA ligase) (AspRS).

SYNC_MOUSE
NC score	0.397224 (rank : 7)	θ value	6.43352e-06 (rank : 7)
Query Neighborhood Hits	19	Target Neighborhood Hits	44	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BP47, Q9CRY5	Gene names	Nars
Domain Architecture
Description	Asparaginyl-tRNA synthetase, cytoplasmic (EC 6.1.1.22) (Asparagine-- tRNA ligase) (AsnRS).

SYNM_MOUSE
NC score	0.385285 (rank : 8)	θ value	0.000158464 (rank : 9)
Query Neighborhood Hits	19	Target Neighborhood Hits	14	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BGV0	Gene names	Nars2
Domain Architecture	No domain graphic available
Description	Probable asparaginyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.22) (Asparagine--tRNA ligase) (AsnRS).

SYNM_HUMAN
NC score	0.373707 (rank : 9)	θ value	9.29e-05 (rank : 8)
Query Neighborhood Hits	19	Target Neighborhood Hits	15	Shared Neighborhood Hits	10
SwissProt Accessions	Q96I59	Gene names	NARS2
Domain Architecture	No domain graphic available
Description	Probable asparaginyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.22) (Asparagine--tRNA ligase) (AsnRS).

SYNC_HUMAN
NC score	0.361189 (rank : 10)	θ value	0.00035302 (rank : 10)
Query Neighborhood Hits	19	Target Neighborhood Hits	47	Shared Neighborhood Hits	10
SwissProt Accessions	O43776	Gene names	NARS, ASNS
Domain Architecture
Description	Asparaginyl-tRNA synthetase, cytoplasmic (EC 6.1.1.22) (Asparagine-- tRNA ligase) (AsnRS).

SASH1_MOUSE
NC score	0.027978 (rank : 11)	θ value	1.81305 (rank : 12)
Query Neighborhood Hits	19	Target Neighborhood Hits	263	Shared Neighborhood Hits	3
SwissProt Accessions	P59808	Gene names	Sash1
Domain Architecture
Description	SAM and SH3 domain-containing protein 1.

FUT9_MOUSE
NC score	0.024733 (rank : 12)	θ value	5.27518 (rank : 15)
Query Neighborhood Hits	19	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	O88819, Q3TQ63	Gene names	Fut9
Domain Architecture	No domain graphic available
Description	Alpha-(1,3)-fucosyltransferase (EC 2.4.1.-) (Galactoside 3-L- fucosyltransferase) (Fucosyltransferase 9) (FUCT-IX).

RUFY3_MOUSE
NC score	0.016193 (rank : 13)	θ value	1.06291 (rank : 11)
Query Neighborhood Hits	19	Target Neighborhood Hits	579	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D394, Q3U348, Q3UF96, Q6PE64, Q8VD10	Gene names	Rufy3, D5Bwg0860e, Ripx
Domain Architecture	No domain graphic available
Description	Protein RUFY3 (Rap2-interacting protein x) (RIPx).

CABYR_MOUSE
NC score	0.015008 (rank : 14)	θ value	8.99809 (rank : 17)
Query Neighborhood Hits	19	Target Neighborhood Hits	80	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D424, Q91Y41, Q91Y42	Gene names	Cabyr, Cbp86
Domain Architecture	No domain graphic available
Description	Calcium-binding tyrosine phosphorylation-regulated protein (Calcium- binding protein 86) (Testis-specific calcium-binding protein CBP86).

ARHGA_MOUSE
NC score	0.013808 (rank : 15)	θ value	4.03905 (rank : 14)
Query Neighborhood Hits	19	Target Neighborhood Hits	125	Shared Neighborhood Hits	2
SwissProt Accessions	Q8C033, Q5DU38, Q80VH8, Q8BW76, Q922S7	Gene names	Arhgef10, Kiaa0294
Domain Architecture
Description	Rho guanine nucleotide exchange factor 10.

HS70L_HUMAN
NC score	0.010211 (rank : 16)	θ value	2.36792 (rank : 13)
Query Neighborhood Hits	19	Target Neighborhood Hits	50	Shared Neighborhood Hits	2
SwissProt Accessions	P34931, O75634, Q2HXR3, Q8NE72, Q96QC9, Q9UQM1	Gene names	HSPA1L
Domain Architecture
Description	Heat shock 70 kDa protein 1L (Heat shock 70 kDa protein 1-like) (Heat shock 70 kDa protein 1-Hom) (HSP70-Hom).

DSC3_MOUSE
NC score	0.003607 (rank : 17)	θ value	6.88961 (rank : 16)
Query Neighborhood Hits	19	Target Neighborhood Hits	154	Shared Neighborhood Hits	2
SwissProt Accessions	P55850, O55110, O55122	Gene names	Dsc3
Domain Architecture
Description	Desmocollin-3 precursor.

ZBT7A_HUMAN
NC score	0.000658 (rank : 18)	θ value	8.99809 (rank : 18)
Query Neighborhood Hits	19	Target Neighborhood Hits	823	Shared Neighborhood Hits	3
SwissProt Accessions	O95365, O00456	Gene names	ZBTB7A, FBI1, LRF, ZBTB7
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 7A (Leukemia/lymphoma- related factor) (Factor that binds to inducer of short transcripts protein 1) (Factor binding IST protein 1) (FBI-1) (HIV-1 1st-binding protein 1) (TTF-I-interacting peptide 21) (TIP21).

ZBT7A_MOUSE
NC score	0.000643 (rank : 19)	θ value	8.99809 (rank : 19)
Query Neighborhood Hits	19	Target Neighborhood Hits	795	Shared Neighborhood Hits	3
SwissProt Accessions	O88939, Q9CRJ0	Gene names	Zbtb7a, Lrf, Zbtb7
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 7A (Leukemia/lymphoma- related factor).