Please be patient as the page loads

Stop Image Loading/Displaying

Network neighborhood for query Sequence : SYNC_MOUSE

For an explanation of this page, click here

SYNC_MOUSE
SwissProt Accessions	Q8BP47, Q9CRY5	Gene names	Nars
Domain Architecture
Description	Asparaginyl-tRNA synthetase, cytoplasmic (EC 6.1.1.22) (Asparagine-- tRNA ligase) (AsnRS).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SYNC_HUMAN
θ value	0 (rank : 1)	NC score	0.994435 (rank : 2)
Query Neighborhood Hits	44	Target Neighborhood Hits	47	Shared Neighborhood Hits	32
SwissProt Accessions	O43776	Gene names	NARS, ASNS
Domain Architecture
Description	Asparaginyl-tRNA synthetase, cytoplasmic (EC 6.1.1.22) (Asparagine-- tRNA ligase) (AsnRS).

SYNC_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	44	Target Neighborhood Hits	44	Shared Neighborhood Hits	44
SwissProt Accessions	Q8BP47, Q9CRY5	Gene names	Nars
Domain Architecture
Description	Asparaginyl-tRNA synthetase, cytoplasmic (EC 6.1.1.22) (Asparagine-- tRNA ligase) (AsnRS).

SYNM_MOUSE
θ value	4.25575e-50 (rank : 3)	NC score	0.857423 (rank : 3)
Query Neighborhood Hits	44	Target Neighborhood Hits	14	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BGV0	Gene names	Nars2
Domain Architecture	No domain graphic available
Description	Probable asparaginyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.22) (Asparagine--tRNA ligase) (AsnRS).

SYNM_HUMAN
θ value	1.51363e-47 (rank : 4)	NC score	0.849259 (rank : 4)
Query Neighborhood Hits	44	Target Neighborhood Hits	15	Shared Neighborhood Hits	10
SwissProt Accessions	Q96I59	Gene names	NARS2
Domain Architecture	No domain graphic available
Description	Probable asparaginyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.22) (Asparagine--tRNA ligase) (AsnRS).

SYDC_MOUSE
θ value	1.85459e-37 (rank : 5)	NC score	0.800934 (rank : 5)
Query Neighborhood Hits	44	Target Neighborhood Hits	15	Shared Neighborhood Hits	10
SwissProt Accessions	Q922B2	Gene names	Dars
Domain Architecture
Description	Aspartyl-tRNA synthetase, cytoplasmic (EC 6.1.1.12) (Aspartate--tRNA ligase) (AspRS).

SYDC_HUMAN
θ value	4.13158e-37 (rank : 6)	NC score	0.800513 (rank : 6)
Query Neighborhood Hits	44	Target Neighborhood Hits	13	Shared Neighborhood Hits	10
SwissProt Accessions	P14868, Q2TNI3, Q32Q69, Q53HV4, Q53YC5, Q9BW52	Gene names	DARS, PIG40
Domain Architecture
Description	Aspartyl-tRNA synthetase, cytoplasmic (EC 6.1.1.12) (Aspartate--tRNA ligase) (AspRS) (Cell proliferation-inducing gene 40 protein).

SYDM_HUMAN
θ value	1.25267e-09 (rank : 7)	NC score	0.477927 (rank : 7)
Query Neighborhood Hits	44	Target Neighborhood Hits	18	Shared Neighborhood Hits	10
SwissProt Accessions	Q6PI48	Gene names	DARS2
Domain Architecture	No domain graphic available
Description	Aspartyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.12) (Aspartate--tRNA ligase) (AspRS).

SYDM_MOUSE
θ value	4.76016e-09 (rank : 8)	NC score	0.444724 (rank : 8)
Query Neighborhood Hits	44	Target Neighborhood Hits	16	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BIP0, Q5FWV4	Gene names	Dars2
Domain Architecture	No domain graphic available
Description	Aspartyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.12) (Aspartate--tRNA ligase) (AspRS).

SYK_HUMAN
θ value	6.43352e-06 (rank : 9)	NC score	0.397224 (rank : 9)
Query Neighborhood Hits	44	Target Neighborhood Hits	19	Shared Neighborhood Hits	10
SwissProt Accessions	Q15046, O14946, Q96J25	Gene names	KARS, KIAA0070
Domain Architecture
Description	Lysyl-tRNA synthetase (EC 6.1.1.6) (Lysine--tRNA ligase) (LysRS).

SYK_MOUSE
θ value	0.000158464 (rank : 10)	NC score	0.380197 (rank : 10)
Query Neighborhood Hits	44	Target Neighborhood Hits	20	Shared Neighborhood Hits	10
SwissProt Accessions	Q99MN1	Gene names	Kars
Domain Architecture
Description	Lysyl-tRNA synthetase (EC 6.1.1.6) (Lysine--tRNA ligase) (LysRS).

CCD45_MOUSE
θ value	0.00869519 (rank : 11)	NC score	0.073996 (rank : 11)
Query Neighborhood Hits	44	Target Neighborhood Hits	663	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BVV7	Gene names	Ccdc45
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 45.

TAF3_MOUSE
θ value	0.163984 (rank : 12)	NC score	0.069968 (rank : 12)
Query Neighborhood Hits	44	Target Neighborhood Hits	463	Shared Neighborhood Hits	12
SwissProt Accessions	Q5HZG4, Q3U490, Q3UWX2, Q8BIU8, Q99JH4	Gene names	Taf3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

HTSF1_HUMAN
θ value	0.365318 (rank : 13)	NC score	0.047952 (rank : 14)
Query Neighborhood Hits	44	Target Neighborhood Hits	408	Shared Neighborhood Hits	7
SwissProt Accessions	O43719, Q59G06, Q99730	Gene names	HTATSF1
Domain Architecture	No domain graphic available
Description	HIV Tat-specific factor 1 (Tat-SF1).

EHMT2_HUMAN
θ value	0.47712 (rank : 14)	NC score	0.023994 (rank : 25)
Query Neighborhood Hits	44	Target Neighborhood Hits	498	Shared Neighborhood Hits	6
SwissProt Accessions	Q96KQ7, Q14349, Q6PK06, Q96MH5, Q96QD0, Q9UQL8, Q9Y331	Gene names	EHMT2, BAT8, G9A, NG36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

MAP1B_MOUSE
θ value	0.47712 (rank : 15)	NC score	0.044325 (rank : 16)
Query Neighborhood Hits	44	Target Neighborhood Hits	977	Shared Neighborhood Hits	11
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

EHMT2_MOUSE
θ value	0.62314 (rank : 16)	NC score	0.023591 (rank : 26)
Query Neighborhood Hits	44	Target Neighborhood Hits	750	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

BRD9_MOUSE
θ value	0.813845 (rank : 17)	NC score	0.036349 (rank : 19)
Query Neighborhood Hits	44	Target Neighborhood Hits	84	Shared Neighborhood Hits	3
SwissProt Accessions	Q3UQU0, Q5FWH1, Q811F7	Gene names	Brd9
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 9.

CNGA1_HUMAN
θ value	0.813845 (rank : 18)	NC score	0.026596 (rank : 24)
Query Neighborhood Hits	44	Target Neighborhood Hits	149	Shared Neighborhood Hits	5
SwissProt Accessions	P29973, Q16279, Q16485	Gene names	CNGA1, CNCG, CNCG1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

CYLC2_HUMAN
θ value	0.813845 (rank : 19)	NC score	0.043574 (rank : 17)
Query Neighborhood Hits	44	Target Neighborhood Hits	223	Shared Neighborhood Hits	8
SwissProt Accessions	Q14093	Gene names	CYLC2, CYL2
Domain Architecture	No domain graphic available
Description	Cylicin-2 (Cylicin II) (Multiple-band polypeptide II).

MAP1B_HUMAN
θ value	1.38821 (rank : 20)	NC score	0.034846 (rank : 20)
Query Neighborhood Hits	44	Target Neighborhood Hits	903	Shared Neighborhood Hits	12
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

P66A_HUMAN
θ value	1.81305 (rank : 21)	NC score	0.034150 (rank : 21)
Query Neighborhood Hits	44	Target Neighborhood Hits	111	Shared Neighborhood Hits	3
SwissProt Accessions	Q86YP4, Q7L3J2, Q96F28, Q9NPU2, Q9NXS1	Gene names	GATAD2A
Domain Architecture	No domain graphic available
Description	Transcriptional repressor p66 alpha (Hp66alpha) (GATA zinc finger domain-containing protein 2A).

RHEB_HUMAN
θ value	1.81305 (rank : 22)	NC score	0.016447 (rank : 31)
Query Neighborhood Hits	44	Target Neighborhood Hits	242	Shared Neighborhood Hits	4
SwissProt Accessions	Q15382, Q99444	Gene names	RHEB, RHEB2
Domain Architecture
Description	GTP-binding protein Rheb (Ras homolog enriched in brain).

CNGA1_MOUSE
θ value	2.36792 (rank : 23)	NC score	0.018459 (rank : 28)
Query Neighborhood Hits	44	Target Neighborhood Hits	198	Shared Neighborhood Hits	3
SwissProt Accessions	P29974, Q60776	Gene names	Cnga1, Cncg, Cncg1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

M4K4_HUMAN
θ value	2.36792 (rank : 24)	NC score	0.006039 (rank : 41)
Query Neighborhood Hits	44	Target Neighborhood Hits	1589	Shared Neighborhood Hits	11
SwissProt Accessions	O95819, O75172, Q9NST7	Gene names	MAP4K4, HGK, KIAA0687, NIK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

M4K4_MOUSE
θ value	2.36792 (rank : 25)	NC score	0.006148 (rank : 40)
Query Neighborhood Hits	44	Target Neighborhood Hits	1560	Shared Neighborhood Hits	12
SwissProt Accessions	P97820	Gene names	Map4k4, Nik
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

RHEB_MOUSE
θ value	2.36792 (rank : 26)	NC score	0.015620 (rank : 33)
Query Neighborhood Hits	44	Target Neighborhood Hits	242	Shared Neighborhood Hits	4
SwissProt Accessions	Q921J2	Gene names	Rheb
Domain Architecture
Description	GTP-binding protein Rheb (Ras homolog enriched in brain).

TRI12_MOUSE
θ value	2.36792 (rank : 27)	NC score	0.008231 (rank : 37)
Query Neighborhood Hits	44	Target Neighborhood Hits	387	Shared Neighborhood Hits	4
SwissProt Accessions	Q99PQ1, Q9D704	Gene names	Trim12
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 12.

CCD45_HUMAN
θ value	3.0926 (rank : 28)	NC score	0.053758 (rank : 13)
Query Neighborhood Hits	44	Target Neighborhood Hits	525	Shared Neighborhood Hits	13
SwissProt Accessions	Q96GE4, Q96M81	Gene names	CCDC45
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 45.

HTSF1_MOUSE
θ value	3.0926 (rank : 29)	NC score	0.031552 (rank : 22)
Query Neighborhood Hits	44	Target Neighborhood Hits	425	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BGC0, Q1WWK0, Q9CT41, Q9DAU3	Gene names	Htatsf1
Domain Architecture	No domain graphic available
Description	HIV Tat-specific factor 1 homolog.

TAF3_HUMAN
θ value	3.0926 (rank : 30)	NC score	0.047728 (rank : 15)
Query Neighborhood Hits	44	Target Neighborhood Hits	568	Shared Neighborhood Hits	13
SwissProt Accessions	Q5VWG9, Q6GMS5, Q6P6B5, Q86VY6, Q9BQS9, Q9UFI8	Gene names	TAF3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

AKA12_HUMAN
θ value	5.27518 (rank : 31)	NC score	0.030680 (rank : 23)
Query Neighborhood Hits	44	Target Neighborhood Hits	825	Shared Neighborhood Hits	15
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

COVA1_HUMAN
θ value	5.27518 (rank : 32)	NC score	0.017006 (rank : 30)
Query Neighborhood Hits	44	Target Neighborhood Hits	416	Shared Neighborhood Hits	5
SwissProt Accessions	Q16206, Q5VTJ1, Q5VTJ2, Q8WUX0, Q9NTP6, Q9UH82	Gene names	COVA1
Domain Architecture
Description	Tumor-associated hydroquinone oxidase (tNOX) (Cytosolic ovarian carcinoma antigen 1) (APK1 antigen) [Includes: Hydroquinone [NADH] oxidase (EC 1.-.-.-); Protein disulfide-thiol oxidoreductase (EC 1.-.-.-)].

KI67_HUMAN
θ value	5.27518 (rank : 33)	NC score	0.020454 (rank : 27)
Query Neighborhood Hits	44	Target Neighborhood Hits	581	Shared Neighborhood Hits	11
SwissProt Accessions	P46013	Gene names	MKI67
Domain Architecture
Description	Antigen KI-67.

SFR17_HUMAN
θ value	5.27518 (rank : 34)	NC score	0.040783 (rank : 18)
Query Neighborhood Hits	44	Target Neighborhood Hits	325	Shared Neighborhood Hits	10
SwissProt Accessions	Q8TF01, Q5T064, Q6P2B4, Q6P2N4, Q6PJ93, Q6PK36, Q7Z640, Q8TF00, Q96K10, Q96SM5, Q9P076, Q9P0C0, Q9Y4N3	Gene names	SRRP130, C6orf111
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 130 (Serine-arginine-rich- splicing regulatory protein 130) (SRrp130) (SR-rich protein) (SR- related protein).

GCP60_MOUSE
θ value	6.88961 (rank : 35)	NC score	0.012332 (rank : 34)
Query Neighborhood Hits	44	Target Neighborhood Hits	395	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BMP6, O35371	Gene names	Acbd3, Gcp60, Pap7
Domain Architecture	No domain graphic available
Description	Golgi resident protein GCP60 (Acyl-CoA-binding domain-containing protein 3) (Golgi phosphoprotein 1) (GOLPH1) (Golgi complex-associated protein 1) (GOCAP1) (PBR- and PKA-associated protein 7) (Peripheral benzodiazepine receptor-associated protein PAP7).

OFD1_HUMAN
θ value	6.88961 (rank : 36)	NC score	0.017134 (rank : 29)
Query Neighborhood Hits	44	Target Neighborhood Hits	753	Shared Neighborhood Hits	11
SwissProt Accessions	O75665, O75666	Gene names	OFD1, CXorf5
Domain Architecture	No domain graphic available
Description	Oral-facial-digital syndrome 1 protein (Protein 71-7A).

RAD50_HUMAN
θ value	6.88961 (rank : 37)	NC score	0.008833 (rank : 36)
Query Neighborhood Hits	44	Target Neighborhood Hits	1317	Shared Neighborhood Hits	23
SwissProt Accessions	Q92878, O43254, Q6GMT7, Q6P5X3, Q9UP86	Gene names	RAD50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (hRAD50).

COVA1_MOUSE
θ value	8.99809 (rank : 38)	NC score	0.015793 (rank : 32)
Query Neighborhood Hits	44	Target Neighborhood Hits	335	Shared Neighborhood Hits	5
SwissProt Accessions	Q8R0Z2, Q8BY59, Q8R372	Gene names	Cova1
Domain Architecture	No domain graphic available
Description	Tumor-associated hydroquinone oxidase (tNOX) (Cytosolic ovarian carcinoma antigen 1) (APK1 antigen) [Includes: Hydroquinone [NADH] oxidase (EC 1.-.-.-); Protein disulfide-thiol oxidoreductase (EC 1.-.-.-)].

CPT1B_MOUSE
θ value	8.99809 (rank : 39)	NC score	0.005719 (rank : 43)
Query Neighborhood Hits	44	Target Neighborhood Hits	24	Shared Neighborhood Hits	2
SwissProt Accessions	Q924X2, O35287, Q9QYP4	Gene names	Cpt1b
Domain Architecture
Description	Carnitine O-palmitoyltransferase I, muscle isoform (EC 2.3.1.21) (CPT I) (CPTI-M) (Carnitine palmitoyltransferase 1B).

DYHC_HUMAN
θ value	8.99809 (rank : 40)	NC score	0.006308 (rank : 39)
Query Neighborhood Hits	44	Target Neighborhood Hits	733	Shared Neighborhood Hits	10
SwissProt Accessions	Q14204, Q6DKQ7, Q8WU28, Q92814, Q9Y4G5	Gene names	DYNC1H1, DNCH1, DNECL, KIAA0325
Domain Architecture	No domain graphic available
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

DYM_MOUSE
θ value	8.99809 (rank : 41)	NC score	0.011834 (rank : 35)
Query Neighborhood Hits	44	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CHY3	Gene names	Dym
Domain Architecture	No domain graphic available
Description	Dymeclin.

EEA1_HUMAN
θ value	8.99809 (rank : 42)	NC score	0.005973 (rank : 42)
Query Neighborhood Hits	44	Target Neighborhood Hits	1796	Shared Neighborhood Hits	21
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

PKP2_HUMAN
θ value	8.99809 (rank : 43)	NC score	0.007145 (rank : 38)
Query Neighborhood Hits	44	Target Neighborhood Hits	40	Shared Neighborhood Hits	2
SwissProt Accessions	Q99959, Q99960	Gene names	PKP2
Domain Architecture
Description	Plakophilin-2.

UBP8_HUMAN
θ value	8.99809 (rank : 44)	NC score	0.005446 (rank : 44)
Query Neighborhood Hits	44	Target Neighborhood Hits	751	Shared Neighborhood Hits	15
SwissProt Accessions	P40818, Q7Z3U2, Q86VA0, Q8IWI7	Gene names	USP8, KIAA0055, UBPY
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (hUBPy).

Hits sorted by NC score

SYNC_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	44	Target Neighborhood Hits	44	Shared Neighborhood Hits	44
SwissProt Accessions	Q8BP47, Q9CRY5	Gene names	Nars
Domain Architecture
Description	Asparaginyl-tRNA synthetase, cytoplasmic (EC 6.1.1.22) (Asparagine-- tRNA ligase) (AsnRS).

SYNC_HUMAN
NC score	0.994435 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	44	Target Neighborhood Hits	47	Shared Neighborhood Hits	32
SwissProt Accessions	O43776	Gene names	NARS, ASNS
Domain Architecture
Description	Asparaginyl-tRNA synthetase, cytoplasmic (EC 6.1.1.22) (Asparagine-- tRNA ligase) (AsnRS).

SYNM_MOUSE
NC score	0.857423 (rank : 3)	θ value	4.25575e-50 (rank : 3)
Query Neighborhood Hits	44	Target Neighborhood Hits	14	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BGV0	Gene names	Nars2
Domain Architecture	No domain graphic available
Description	Probable asparaginyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.22) (Asparagine--tRNA ligase) (AsnRS).

SYNM_HUMAN
NC score	0.849259 (rank : 4)	θ value	1.51363e-47 (rank : 4)
Query Neighborhood Hits	44	Target Neighborhood Hits	15	Shared Neighborhood Hits	10
SwissProt Accessions	Q96I59	Gene names	NARS2
Domain Architecture	No domain graphic available
Description	Probable asparaginyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.22) (Asparagine--tRNA ligase) (AsnRS).

SYDC_MOUSE
NC score	0.800934 (rank : 5)	θ value	1.85459e-37 (rank : 5)
Query Neighborhood Hits	44	Target Neighborhood Hits	15	Shared Neighborhood Hits	10
SwissProt Accessions	Q922B2	Gene names	Dars
Domain Architecture
Description	Aspartyl-tRNA synthetase, cytoplasmic (EC 6.1.1.12) (Aspartate--tRNA ligase) (AspRS).

SYDC_HUMAN
NC score	0.800513 (rank : 6)	θ value	4.13158e-37 (rank : 6)
Query Neighborhood Hits	44	Target Neighborhood Hits	13	Shared Neighborhood Hits	10
SwissProt Accessions	P14868, Q2TNI3, Q32Q69, Q53HV4, Q53YC5, Q9BW52	Gene names	DARS, PIG40
Domain Architecture
Description	Aspartyl-tRNA synthetase, cytoplasmic (EC 6.1.1.12) (Aspartate--tRNA ligase) (AspRS) (Cell proliferation-inducing gene 40 protein).

SYDM_HUMAN
NC score	0.477927 (rank : 7)	θ value	1.25267e-09 (rank : 7)
Query Neighborhood Hits	44	Target Neighborhood Hits	18	Shared Neighborhood Hits	10
SwissProt Accessions	Q6PI48	Gene names	DARS2
Domain Architecture	No domain graphic available
Description	Aspartyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.12) (Aspartate--tRNA ligase) (AspRS).

SYDM_MOUSE
NC score	0.444724 (rank : 8)	θ value	4.76016e-09 (rank : 8)
Query Neighborhood Hits	44	Target Neighborhood Hits	16	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BIP0, Q5FWV4	Gene names	Dars2
Domain Architecture	No domain graphic available
Description	Aspartyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.12) (Aspartate--tRNA ligase) (AspRS).

SYK_HUMAN
NC score	0.397224 (rank : 9)	θ value	6.43352e-06 (rank : 9)
Query Neighborhood Hits	44	Target Neighborhood Hits	19	Shared Neighborhood Hits	10
SwissProt Accessions	Q15046, O14946, Q96J25	Gene names	KARS, KIAA0070
Domain Architecture
Description	Lysyl-tRNA synthetase (EC 6.1.1.6) (Lysine--tRNA ligase) (LysRS).

SYK_MOUSE
NC score	0.380197 (rank : 10)	θ value	0.000158464 (rank : 10)
Query Neighborhood Hits	44	Target Neighborhood Hits	20	Shared Neighborhood Hits	10
SwissProt Accessions	Q99MN1	Gene names	Kars
Domain Architecture
Description	Lysyl-tRNA synthetase (EC 6.1.1.6) (Lysine--tRNA ligase) (LysRS).

CCD45_MOUSE
NC score	0.073996 (rank : 11)	θ value	0.00869519 (rank : 11)
Query Neighborhood Hits	44	Target Neighborhood Hits	663	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BVV7	Gene names	Ccdc45
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 45.

TAF3_MOUSE
NC score	0.069968 (rank : 12)	θ value	0.163984 (rank : 12)
Query Neighborhood Hits	44	Target Neighborhood Hits	463	Shared Neighborhood Hits	12
SwissProt Accessions	Q5HZG4, Q3U490, Q3UWX2, Q8BIU8, Q99JH4	Gene names	Taf3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

CCD45_HUMAN
NC score	0.053758 (rank : 13)	θ value	3.0926 (rank : 28)
Query Neighborhood Hits	44	Target Neighborhood Hits	525	Shared Neighborhood Hits	13
SwissProt Accessions	Q96GE4, Q96M81	Gene names	CCDC45
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 45.

HTSF1_HUMAN
NC score	0.047952 (rank : 14)	θ value	0.365318 (rank : 13)
Query Neighborhood Hits	44	Target Neighborhood Hits	408	Shared Neighborhood Hits	7
SwissProt Accessions	O43719, Q59G06, Q99730	Gene names	HTATSF1
Domain Architecture	No domain graphic available
Description	HIV Tat-specific factor 1 (Tat-SF1).

TAF3_HUMAN
NC score	0.047728 (rank : 15)	θ value	3.0926 (rank : 30)
Query Neighborhood Hits	44	Target Neighborhood Hits	568	Shared Neighborhood Hits	13
SwissProt Accessions	Q5VWG9, Q6GMS5, Q6P6B5, Q86VY6, Q9BQS9, Q9UFI8	Gene names	TAF3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

MAP1B_MOUSE
NC score	0.044325 (rank : 16)	θ value	0.47712 (rank : 15)
Query Neighborhood Hits	44	Target Neighborhood Hits	977	Shared Neighborhood Hits	11
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

CYLC2_HUMAN
NC score	0.043574 (rank : 17)	θ value	0.813845 (rank : 19)
Query Neighborhood Hits	44	Target Neighborhood Hits	223	Shared Neighborhood Hits	8
SwissProt Accessions	Q14093	Gene names	CYLC2, CYL2
Domain Architecture	No domain graphic available
Description	Cylicin-2 (Cylicin II) (Multiple-band polypeptide II).

SFR17_HUMAN
NC score	0.040783 (rank : 18)	θ value	5.27518 (rank : 34)
Query Neighborhood Hits	44	Target Neighborhood Hits	325	Shared Neighborhood Hits	10
SwissProt Accessions	Q8TF01, Q5T064, Q6P2B4, Q6P2N4, Q6PJ93, Q6PK36, Q7Z640, Q8TF00, Q96K10, Q96SM5, Q9P076, Q9P0C0, Q9Y4N3	Gene names	SRRP130, C6orf111
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 130 (Serine-arginine-rich- splicing regulatory protein 130) (SRrp130) (SR-rich protein) (SR- related protein).

BRD9_MOUSE
NC score	0.036349 (rank : 19)	θ value	0.813845 (rank : 17)
Query Neighborhood Hits	44	Target Neighborhood Hits	84	Shared Neighborhood Hits	3
SwissProt Accessions	Q3UQU0, Q5FWH1, Q811F7	Gene names	Brd9
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 9.

MAP1B_HUMAN
NC score	0.034846 (rank : 20)	θ value	1.38821 (rank : 20)
Query Neighborhood Hits	44	Target Neighborhood Hits	903	Shared Neighborhood Hits	12
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

P66A_HUMAN
NC score	0.034150 (rank : 21)	θ value	1.81305 (rank : 21)
Query Neighborhood Hits	44	Target Neighborhood Hits	111	Shared Neighborhood Hits	3
SwissProt Accessions	Q86YP4, Q7L3J2, Q96F28, Q9NPU2, Q9NXS1	Gene names	GATAD2A
Domain Architecture	No domain graphic available
Description	Transcriptional repressor p66 alpha (Hp66alpha) (GATA zinc finger domain-containing protein 2A).

HTSF1_MOUSE
NC score	0.031552 (rank : 22)	θ value	3.0926 (rank : 29)
Query Neighborhood Hits	44	Target Neighborhood Hits	425	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BGC0, Q1WWK0, Q9CT41, Q9DAU3	Gene names	Htatsf1
Domain Architecture	No domain graphic available
Description	HIV Tat-specific factor 1 homolog.

AKA12_HUMAN
NC score	0.030680 (rank : 23)	θ value	5.27518 (rank : 31)
Query Neighborhood Hits	44	Target Neighborhood Hits	825	Shared Neighborhood Hits	15
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

CNGA1_HUMAN
NC score	0.026596 (rank : 24)	θ value	0.813845 (rank : 18)
Query Neighborhood Hits	44	Target Neighborhood Hits	149	Shared Neighborhood Hits	5
SwissProt Accessions	P29973, Q16279, Q16485	Gene names	CNGA1, CNCG, CNCG1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

EHMT2_HUMAN
NC score	0.023994 (rank : 25)	θ value	0.47712 (rank : 14)
Query Neighborhood Hits	44	Target Neighborhood Hits	498	Shared Neighborhood Hits	6
SwissProt Accessions	Q96KQ7, Q14349, Q6PK06, Q96MH5, Q96QD0, Q9UQL8, Q9Y331	Gene names	EHMT2, BAT8, G9A, NG36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

EHMT2_MOUSE
NC score	0.023591 (rank : 26)	θ value	0.62314 (rank : 16)
Query Neighborhood Hits	44	Target Neighborhood Hits	750	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

KI67_HUMAN
NC score	0.020454 (rank : 27)	θ value	5.27518 (rank : 33)
Query Neighborhood Hits	44	Target Neighborhood Hits	581	Shared Neighborhood Hits	11
SwissProt Accessions	P46013	Gene names	MKI67
Domain Architecture
Description	Antigen KI-67.

CNGA1_MOUSE
NC score	0.018459 (rank : 28)	θ value	2.36792 (rank : 23)
Query Neighborhood Hits	44	Target Neighborhood Hits	198	Shared Neighborhood Hits	3
SwissProt Accessions	P29974, Q60776	Gene names	Cnga1, Cncg, Cncg1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

OFD1_HUMAN
NC score	0.017134 (rank : 29)	θ value	6.88961 (rank : 36)
Query Neighborhood Hits	44	Target Neighborhood Hits	753	Shared Neighborhood Hits	11
SwissProt Accessions	O75665, O75666	Gene names	OFD1, CXorf5
Domain Architecture	No domain graphic available
Description	Oral-facial-digital syndrome 1 protein (Protein 71-7A).

COVA1_HUMAN
NC score	0.017006 (rank : 30)	θ value	5.27518 (rank : 32)
Query Neighborhood Hits	44	Target Neighborhood Hits	416	Shared Neighborhood Hits	5
SwissProt Accessions	Q16206, Q5VTJ1, Q5VTJ2, Q8WUX0, Q9NTP6, Q9UH82	Gene names	COVA1
Domain Architecture
Description	Tumor-associated hydroquinone oxidase (tNOX) (Cytosolic ovarian carcinoma antigen 1) (APK1 antigen) [Includes: Hydroquinone [NADH] oxidase (EC 1.-.-.-); Protein disulfide-thiol oxidoreductase (EC 1.-.-.-)].

RHEB_HUMAN
NC score	0.016447 (rank : 31)	θ value	1.81305 (rank : 22)
Query Neighborhood Hits	44	Target Neighborhood Hits	242	Shared Neighborhood Hits	4
SwissProt Accessions	Q15382, Q99444	Gene names	RHEB, RHEB2
Domain Architecture
Description	GTP-binding protein Rheb (Ras homolog enriched in brain).

COVA1_MOUSE
NC score	0.015793 (rank : 32)	θ value	8.99809 (rank : 38)
Query Neighborhood Hits	44	Target Neighborhood Hits	335	Shared Neighborhood Hits	5
SwissProt Accessions	Q8R0Z2, Q8BY59, Q8R372	Gene names	Cova1
Domain Architecture	No domain graphic available
Description	Tumor-associated hydroquinone oxidase (tNOX) (Cytosolic ovarian carcinoma antigen 1) (APK1 antigen) [Includes: Hydroquinone [NADH] oxidase (EC 1.-.-.-); Protein disulfide-thiol oxidoreductase (EC 1.-.-.-)].

RHEB_MOUSE
NC score	0.015620 (rank : 33)	θ value	2.36792 (rank : 26)
Query Neighborhood Hits	44	Target Neighborhood Hits	242	Shared Neighborhood Hits	4
SwissProt Accessions	Q921J2	Gene names	Rheb
Domain Architecture
Description	GTP-binding protein Rheb (Ras homolog enriched in brain).

GCP60_MOUSE
NC score	0.012332 (rank : 34)	θ value	6.88961 (rank : 35)
Query Neighborhood Hits	44	Target Neighborhood Hits	395	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BMP6, O35371	Gene names	Acbd3, Gcp60, Pap7
Domain Architecture	No domain graphic available
Description	Golgi resident protein GCP60 (Acyl-CoA-binding domain-containing protein 3) (Golgi phosphoprotein 1) (GOLPH1) (Golgi complex-associated protein 1) (GOCAP1) (PBR- and PKA-associated protein 7) (Peripheral benzodiazepine receptor-associated protein PAP7).

DYM_MOUSE
NC score	0.011834 (rank : 35)	θ value	8.99809 (rank : 41)
Query Neighborhood Hits	44	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CHY3	Gene names	Dym
Domain Architecture	No domain graphic available
Description	Dymeclin.

RAD50_HUMAN
NC score	0.008833 (rank : 36)	θ value	6.88961 (rank : 37)
Query Neighborhood Hits	44	Target Neighborhood Hits	1317	Shared Neighborhood Hits	23
SwissProt Accessions	Q92878, O43254, Q6GMT7, Q6P5X3, Q9UP86	Gene names	RAD50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (hRAD50).

TRI12_MOUSE
NC score	0.008231 (rank : 37)	θ value	2.36792 (rank : 27)
Query Neighborhood Hits	44	Target Neighborhood Hits	387	Shared Neighborhood Hits	4
SwissProt Accessions	Q99PQ1, Q9D704	Gene names	Trim12
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 12.

PKP2_HUMAN
NC score	0.007145 (rank : 38)	θ value	8.99809 (rank : 43)
Query Neighborhood Hits	44	Target Neighborhood Hits	40	Shared Neighborhood Hits	2
SwissProt Accessions	Q99959, Q99960	Gene names	PKP2
Domain Architecture
Description	Plakophilin-2.

DYHC_HUMAN
NC score	0.006308 (rank : 39)	θ value	8.99809 (rank : 40)
Query Neighborhood Hits	44	Target Neighborhood Hits	733	Shared Neighborhood Hits	10
SwissProt Accessions	Q14204, Q6DKQ7, Q8WU28, Q92814, Q9Y4G5	Gene names	DYNC1H1, DNCH1, DNECL, KIAA0325
Domain Architecture	No domain graphic available
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

M4K4_MOUSE
NC score	0.006148 (rank : 40)	θ value	2.36792 (rank : 25)
Query Neighborhood Hits	44	Target Neighborhood Hits	1560	Shared Neighborhood Hits	12
SwissProt Accessions	P97820	Gene names	Map4k4, Nik
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

M4K4_HUMAN
NC score	0.006039 (rank : 41)	θ value	2.36792 (rank : 24)
Query Neighborhood Hits	44	Target Neighborhood Hits	1589	Shared Neighborhood Hits	11
SwissProt Accessions	O95819, O75172, Q9NST7	Gene names	MAP4K4, HGK, KIAA0687, NIK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

EEA1_HUMAN
NC score	0.005973 (rank : 42)	θ value	8.99809 (rank : 42)
Query Neighborhood Hits	44	Target Neighborhood Hits	1796	Shared Neighborhood Hits	21
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

CPT1B_MOUSE
NC score	0.005719 (rank : 43)	θ value	8.99809 (rank : 39)
Query Neighborhood Hits	44	Target Neighborhood Hits	24	Shared Neighborhood Hits	2
SwissProt Accessions	Q924X2, O35287, Q9QYP4	Gene names	Cpt1b
Domain Architecture
Description	Carnitine O-palmitoyltransferase I, muscle isoform (EC 2.3.1.21) (CPT I) (CPTI-M) (Carnitine palmitoyltransferase 1B).

UBP8_HUMAN
NC score	0.005446 (rank : 44)	θ value	8.99809 (rank : 44)
Query Neighborhood Hits	44	Target Neighborhood Hits	751	Shared Neighborhood Hits	15
SwissProt Accessions	P40818, Q7Z3U2, Q86VA0, Q8IWI7	Gene names	USP8, KIAA0055, UBPY
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (hUBPy).