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Network neighborhood for query Sequence : STAT4_MOUSE

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STAT4_MOUSE
SwissProt Accessions	P42228	Gene names	Stat4
Domain Architecture
Description	Signal transducer and activator of transcription 4.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

STAT1_HUMAN
θ value	0 (rank : 1)	NC score	0.976428 (rank : 3)
Query Neighborhood Hits	73	Target Neighborhood Hits	128	Shared Neighborhood Hits	33
SwissProt Accessions	P42224	Gene names	STAT1
Domain Architecture
Description	Signal transducer and activator of transcription 1-alpha/beta (Transcription factor ISGF-3 components p91/p84).

STAT1_MOUSE
θ value	0 (rank : 2)	NC score	0.973735 (rank : 4)
Query Neighborhood Hits	73	Target Neighborhood Hits	151	Shared Neighborhood Hits	33
SwissProt Accessions	P42225	Gene names	Stat1
Domain Architecture
Description	Signal transducer and activator of transcription 1.

STAT3_HUMAN
θ value	0 (rank : 3)	NC score	0.970319 (rank : 5)
Query Neighborhood Hits	73	Target Neighborhood Hits	155	Shared Neighborhood Hits	29
SwissProt Accessions	P40763, O14916, Q9BW54	Gene names	STAT3, APRF
Domain Architecture
Description	Signal transducer and activator of transcription 3 (Acute-phase response factor).

STAT3_MOUSE
θ value	0 (rank : 4)	NC score	0.970318 (rank : 6)
Query Neighborhood Hits	73	Target Neighborhood Hits	155	Shared Neighborhood Hits	29
SwissProt Accessions	P42227	Gene names	Stat3, Aprf
Domain Architecture
Description	Signal transducer and activator of transcription 3 (Acute-phase response factor).

STAT4_HUMAN
θ value	0 (rank : 5)	NC score	0.991351 (rank : 2)
Query Neighborhood Hits	73	Target Neighborhood Hits	91	Shared Neighborhood Hits	46
SwissProt Accessions	Q14765, Q96NZ6	Gene names	STAT4
Domain Architecture
Description	Signal transducer and activator of transcription 4.

STAT4_MOUSE
θ value	0 (rank : 6)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	73	Target Neighborhood Hits	73	Shared Neighborhood Hits	73
SwissProt Accessions	P42228	Gene names	Stat4
Domain Architecture
Description	Signal transducer and activator of transcription 4.

STAT2_HUMAN
θ value	8.37844e-131 (rank : 7)	NC score	0.967100 (rank : 7)
Query Neighborhood Hits	73	Target Neighborhood Hits	99	Shared Neighborhood Hits	20
SwissProt Accessions	P52630, Q16430, Q16431	Gene names	STAT2
Domain Architecture
Description	Signal transducer and activator of transcription 2 (p113).

STAT2_MOUSE
θ value	1.29561e-123 (rank : 8)	NC score	0.918194 (rank : 8)
Query Neighborhood Hits	73	Target Neighborhood Hits	175	Shared Neighborhood Hits	16
SwissProt Accessions	Q9WVL2, Q64188, Q64189, Q64250	Gene names	Stat2
Domain Architecture
Description	Signal transducer and activator of transcription 2.

STA5B_MOUSE
θ value	1.18549e-84 (rank : 9)	NC score	0.900733 (rank : 10)
Query Neighborhood Hits	73	Target Neighborhood Hits	124	Shared Neighborhood Hits	32
SwissProt Accessions	P42232, Q541Q5, Q60804, Q8K3Q1, Q9JKM1	Gene names	Stat5b
Domain Architecture
Description	Signal transducer and activator of transcription 5B.

STA5B_HUMAN
θ value	5.50685e-82 (rank : 10)	NC score	0.902819 (rank : 9)
Query Neighborhood Hits	73	Target Neighborhood Hits	103	Shared Neighborhood Hits	28
SwissProt Accessions	P51692, Q8WWS8	Gene names	STAT5B
Domain Architecture
Description	Signal transducer and activator of transcription 5B.

STA5A_MOUSE
θ value	3.69378e-78 (rank : 11)	NC score	0.896843 (rank : 11)
Query Neighborhood Hits	73	Target Neighborhood Hits	128	Shared Neighborhood Hits	31
SwissProt Accessions	P42230	Gene names	Stat5a, Mgf, Mpf
Domain Architecture
Description	Signal transducer and activator of transcription 5A (Mammary gland factor).

STA5A_HUMAN
θ value	4.51533e-76 (rank : 12)	NC score	0.894557 (rank : 12)
Query Neighborhood Hits	73	Target Neighborhood Hits	140	Shared Neighborhood Hits	32
SwissProt Accessions	P42229	Gene names	STAT5A, STAT5
Domain Architecture
Description	Signal transducer and activator of transcription 5A.

STAT6_HUMAN
θ value	1.41344e-53 (rank : 13)	NC score	0.867572 (rank : 14)
Query Neighborhood Hits	73	Target Neighborhood Hits	132	Shared Neighborhood Hits	18
SwissProt Accessions	P42226	Gene names	STAT6
Domain Architecture
Description	Signal transducer and activator of transcription 6 (IL-4 Stat).

STAT6_MOUSE
θ value	1.01294e-51 (rank : 14)	NC score	0.871283 (rank : 13)
Query Neighborhood Hits	73	Target Neighborhood Hits	78	Shared Neighborhood Hits	15
SwissProt Accessions	P52633	Gene names	Stat6
Domain Architecture
Description	Signal transducer and transcription activator 6.

KTN1_HUMAN
θ value	0.00228821 (rank : 15)	NC score	0.049028 (rank : 21)
Query Neighborhood Hits	73	Target Neighborhood Hits	1197	Shared Neighborhood Hits	46
SwissProt Accessions	Q86UP2, Q13999, Q14707, Q15387, Q86W57	Gene names	KTN1, CG1, KIAA0004
Domain Architecture	No domain graphic available
Description	Kinectin (Kinesin receptor) (CG-1 antigen).

NIN_HUMAN
θ value	0.163984 (rank : 16)	NC score	0.037361 (rank : 32)
Query Neighborhood Hits	73	Target Neighborhood Hits	1416	Shared Neighborhood Hits	46
SwissProt Accessions	Q8N4C6, Q6P0P6, Q9BWU6, Q9C012, Q9C013, Q9C014, Q9H5I6, Q9HAT7, Q9HBY5, Q9HCK7, Q9UH61	Gene names	NIN, KIAA1565
Domain Architecture	No domain graphic available
Description	Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein).

UGGG2_HUMAN
θ value	0.163984 (rank : 17)	NC score	0.034903 (rank : 35)
Query Neighborhood Hits	73	Target Neighborhood Hits	32	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NYU1, Q9UFC4	Gene names	UGCGL2, UGT2
Domain Architecture
Description	UDP-glucose:glycoprotein glucosyltransferase 2 precursor (EC 2.4.1.-) (UDP-glucose ceramide glucosyltransferase-like 1) (UDP-- Glc:glycoprotein glucosyltransferase 2) (HUGT2).

HMMR_MOUSE
θ value	0.21417 (rank : 18)	NC score	0.032337 (rank : 42)
Query Neighborhood Hits	73	Target Neighborhood Hits	1178	Shared Neighborhood Hits	45
SwissProt Accessions	Q00547	Gene names	Hmmr, Ihabp, Rhamm
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility).

GOGA5_MOUSE
θ value	0.279714 (rank : 19)	NC score	0.033823 (rank : 37)
Query Neighborhood Hits	73	Target Neighborhood Hits	1434	Shared Neighborhood Hits	47
SwissProt Accessions	Q9QYE6, O88317, Q3TGE7, Q3U6S5, Q3UUF9	Gene names	Golga5, Retii
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (Sumiko protein) (Ret-II protein).

CAR11_HUMAN
θ value	0.47712 (rank : 20)	NC score	0.030379 (rank : 45)
Query Neighborhood Hits	73	Target Neighborhood Hits	690	Shared Neighborhood Hits	41
SwissProt Accessions	Q9BXL7, Q548H3	Gene names	CARD11, CARMA1
Domain Architecture
Description	Caspase recruitment domain-containing protein 11 (CARD-containing MAGUK protein 3) (Carma 1).

UACA_HUMAN
θ value	0.47712 (rank : 21)	NC score	0.027654 (rank : 48)
Query Neighborhood Hits	73	Target Neighborhood Hits	1622	Shared Neighborhood Hits	46
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

BRE1A_HUMAN
θ value	0.62314 (rank : 22)	NC score	0.040248 (rank : 31)
Query Neighborhood Hits	73	Target Neighborhood Hits	1071	Shared Neighborhood Hits	45
SwissProt Accessions	Q5VTR2, Q69YL5, Q6P527, Q8N3J4, Q96JD3, Q9H9Y7, Q9HA51, Q9NUR4, Q9NWQ3, Q9NX83	Gene names	RNF20, BRE1A
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (hBRE1) (RING finger protein 20).

BRE1A_MOUSE
θ value	0.62314 (rank : 23)	NC score	0.036524 (rank : 34)
Query Neighborhood Hits	73	Target Neighborhood Hits	1025	Shared Neighborhood Hits	45
SwissProt Accessions	Q5DTM8, Q3UT10, Q3V350, Q7TT11, Q8BKA8, Q8BKN8, Q8BUF7, Q8BVU4	Gene names	Rnf20, Bre1a, Kiaa4116
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (RING finger protein 20).

HSH2D_MOUSE
θ value	0.62314 (rank : 24)	NC score	0.065342 (rank : 16)
Query Neighborhood Hits	73	Target Neighborhood Hits	124	Shared Neighborhood Hits	14
SwissProt Accessions	Q6VYH9, Q52KL3	Gene names	Hsh2d, Alx
Domain Architecture	No domain graphic available
Description	Hematopoietic SH2 domain-containing protein (Hematopoietic SH2 protein) (Adaptor in lymphocytes of unknown function X).

LRC45_HUMAN
θ value	0.62314 (rank : 25)	NC score	0.025550 (rank : 51)
Query Neighborhood Hits	73	Target Neighborhood Hits	933	Shared Neighborhood Hits	38
SwissProt Accessions	Q96CN5	Gene names	LRRC45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

GOGA4_MOUSE
θ value	0.813845 (rank : 26)	NC score	0.041984 (rank : 30)
Query Neighborhood Hits	73	Target Neighborhood Hits	1939	Shared Neighborhood Hits	55
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

K0082_HUMAN
θ value	0.813845 (rank : 27)	NC score	0.043849 (rank : 26)
Query Neighborhood Hits	73	Target Neighborhood Hits	60	Shared Neighborhood Hits	4
SwissProt Accessions	Q8N1G2, Q14670, Q96FJ9	Gene names	KIAA0082
Domain Architecture	No domain graphic available
Description	Protein KIAA0082.

K2C1_HUMAN
θ value	0.813845 (rank : 28)	NC score	0.016368 (rank : 64)
Query Neighborhood Hits	73	Target Neighborhood Hits	624	Shared Neighborhood Hits	38
SwissProt Accessions	P04264, Q14720, Q6GSJ0, Q9H298	Gene names	KRT1, KRTA
Domain Architecture
Description	Keratin, type II cytoskeletal 1 (Cytokeratin-1) (CK-1) (Keratin-1) (K1) (67 kDa cytokeratin) (Hair alpha protein).

MYH11_HUMAN
θ value	0.813845 (rank : 29)	NC score	0.023229 (rank : 58)
Query Neighborhood Hits	73	Target Neighborhood Hits	1806	Shared Neighborhood Hits	47
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

PCNT_MOUSE
θ value	0.813845 (rank : 30)	NC score	0.033102 (rank : 41)
Query Neighborhood Hits	73	Target Neighborhood Hits	1207	Shared Neighborhood Hits	45
SwissProt Accessions	P48725	Gene names	Pcnt, Pcnt2
Domain Architecture	No domain graphic available
Description	Pericentrin.

PTN11_HUMAN
θ value	0.813845 (rank : 31)	NC score	0.012435 (rank : 65)
Query Neighborhood Hits	73	Target Neighborhood Hits	227	Shared Neighborhood Hits	9
SwissProt Accessions	Q06124, Q96HD7	Gene names	PTPN11, PTP2C, SHPTP2
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase 2C) (PTP-2C) (PTP-1D) (SH-PTP3) (SH- PTP2) (SHP-2) (Shp2).

PTN11_MOUSE
θ value	0.813845 (rank : 32)	NC score	0.012412 (rank : 66)
Query Neighborhood Hits	73	Target Neighborhood Hits	227	Shared Neighborhood Hits	8
SwissProt Accessions	P35235, Q3TQ84, Q64509, Q6PCL5	Gene names	Ptpn11
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase SYP) (SH-PTP2) (SHP-2) (Shp2).

TRIPB_HUMAN
θ value	0.813845 (rank : 33)	NC score	0.045875 (rank : 22)
Query Neighborhood Hits	73	Target Neighborhood Hits	1587	Shared Neighborhood Hits	52
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

K0082_MOUSE
θ value	1.06291 (rank : 34)	NC score	0.042525 (rank : 28)
Query Neighborhood Hits	73	Target Neighborhood Hits	62	Shared Neighborhood Hits	4
SwissProt Accessions	Q9DBC3, Q3U3G5, Q3U7Y9, Q6A0D5, Q8C7V0	Gene names	Kiaa0082
Domain Architecture	No domain graphic available
Description	Protein KIAA0082.

UACA_MOUSE
θ value	1.06291 (rank : 35)	NC score	0.028676 (rank : 46)
Query Neighborhood Hits	73	Target Neighborhood Hits	1620	Shared Neighborhood Hits	45
SwissProt Accessions	Q8CGB3, Q69ZG3, Q7TN77, Q8BJC8	Gene names	Uaca, Kiaa1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein (Nucling) (Nuclear membrane-binding protein).

ADIP_MOUSE
θ value	1.38821 (rank : 36)	NC score	0.045712 (rank : 23)
Query Neighborhood Hits	73	Target Neighborhood Hits	415	Shared Neighborhood Hits	38
SwissProt Accessions	Q8VC66, Q8BG59, Q8C7X0, Q8K2F7	Gene names	Ssx2ip
Domain Architecture	No domain graphic available
Description	Afadin- and alpha-actinin-binding protein (ADIP) (Afadin DIL domain- interacting protein).

SYAP1_HUMAN
θ value	1.38821 (rank : 37)	NC score	0.027971 (rank : 47)
Query Neighborhood Hits	73	Target Neighborhood Hits	58	Shared Neighborhood Hits	9
SwissProt Accessions	Q96A49, Q96C60, Q96JQ6, Q96T20	Gene names	SYAP1
Domain Architecture
Description	Synapse-associated protein 1.

SYNE2_HUMAN
θ value	1.38821 (rank : 38)	NC score	0.023596 (rank : 56)
Query Neighborhood Hits	73	Target Neighborhood Hits	1323	Shared Neighborhood Hits	41
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

ADIP_HUMAN
θ value	1.81305 (rank : 39)	NC score	0.043381 (rank : 27)
Query Neighborhood Hits	73	Target Neighborhood Hits	470	Shared Neighborhood Hits	38
SwissProt Accessions	Q9Y2D8, Q6P2P8, Q6ULS1, Q7L168, Q9UIX0	Gene names	SSX2IP, KIAA0923
Domain Architecture	No domain graphic available
Description	Afadin- and alpha-actinin-binding protein (ADIP) (Afadin DIL domain- interacting protein) (SSX2-interacting protein).

EP15_HUMAN
θ value	1.81305 (rank : 40)	NC score	0.033163 (rank : 40)
Query Neighborhood Hits	73	Target Neighborhood Hits	1021	Shared Neighborhood Hits	45
SwissProt Accessions	P42566	Gene names	EPS15, AF1P
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

GCC2_HUMAN
θ value	1.81305 (rank : 41)	NC score	0.033594 (rank : 38)
Query Neighborhood Hits	73	Target Neighborhood Hits	1558	Shared Neighborhood Hits	47
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

GOGA5_HUMAN
θ value	1.81305 (rank : 42)	NC score	0.031665 (rank : 43)
Query Neighborhood Hits	73	Target Neighborhood Hits	1168	Shared Neighborhood Hits	43
SwissProt Accessions	Q8TBA6, O95287, Q03962, Q9UQQ7	Gene names	GOLGA5, RETII, RFG5
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (RET-fused gene 5 protein) (Ret-II protein).

LRSM1_HUMAN
θ value	1.81305 (rank : 43)	NC score	0.024456 (rank : 53)
Query Neighborhood Hits	73	Target Neighborhood Hits	1078	Shared Neighborhood Hits	45
SwissProt Accessions	Q6UWE0, Q5VVV0, Q8NB40, Q96GT5, Q96MX5, Q96MZ7	Gene names	LRSAM1, TAL
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) (hTAL).

CCD91_HUMAN
θ value	2.36792 (rank : 44)	NC score	0.034162 (rank : 36)
Query Neighborhood Hits	73	Target Neighborhood Hits	868	Shared Neighborhood Hits	38
SwissProt Accessions	Q7Z6B0, Q68D43, Q6IA78, Q8NEN7, Q9NUW9	Gene names	CCDC91, GGABP
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner) (p56 accessory protein).

CT096_HUMAN
θ value	2.36792 (rank : 45)	NC score	0.031164 (rank : 44)
Query Neighborhood Hits	73	Target Neighborhood Hits	438	Shared Neighborhood Hits	37
SwissProt Accessions	Q9NUD7, Q8N840, Q8NAX5	Gene names	C20orf96
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf96.

PROX1_MOUSE
θ value	2.36792 (rank : 46)	NC score	0.026593 (rank : 50)
Query Neighborhood Hits	73	Target Neighborhood Hits	184	Shared Neighborhood Hits	24
SwissProt Accessions	P48437, O88478, Q3UPV1, Q543D8	Gene names	Prox1
Domain Architecture
Description	Homeobox prospero-like protein PROX1 (PROX 1).

TPR_HUMAN
θ value	2.36792 (rank : 47)	NC score	0.044123 (rank : 25)
Query Neighborhood Hits	73	Target Neighborhood Hits	1921	Shared Neighborhood Hits	50
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

CCD27_HUMAN
θ value	3.0926 (rank : 48)	NC score	0.065272 (rank : 17)
Query Neighborhood Hits	73	Target Neighborhood Hits	594	Shared Neighborhood Hits	41
SwissProt Accessions	Q2M243, Q5TBV3, Q96M50	Gene names	CCDC27
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 27.

HMMR_HUMAN
θ value	3.0926 (rank : 49)	NC score	0.042371 (rank : 29)
Query Neighborhood Hits	73	Target Neighborhood Hits	1082	Shared Neighborhood Hits	49
SwissProt Accessions	O75330, Q92767	Gene names	HMMR, IHABP, RHAMM
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen).

CP135_MOUSE
θ value	4.03905 (rank : 50)	NC score	0.036528 (rank : 33)
Query Neighborhood Hits	73	Target Neighborhood Hits	1278	Shared Neighborhood Hits	48
SwissProt Accessions	Q6P5D4, Q6A030	Gene names	Cep135, Cep4, Kiaa0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

IRS2_MOUSE
θ value	4.03905 (rank : 51)	NC score	0.010949 (rank : 69)
Query Neighborhood Hits	73	Target Neighborhood Hits	248	Shared Neighborhood Hits	3
SwissProt Accessions	P81122	Gene names	Irs2
Domain Architecture	No domain graphic available
Description	Insulin receptor substrate 2 (IRS-2) (4PS).

LIPA1_HUMAN
θ value	4.03905 (rank : 52)	NC score	0.027190 (rank : 49)
Query Neighborhood Hits	73	Target Neighborhood Hits	1294	Shared Neighborhood Hits	42
SwissProt Accessions	Q13136, Q13135, Q14567, Q8N4I2	Gene names	PPFIA1, LIP1
Domain Architecture
Description	Liprin-alpha-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1) (PTPRF-interacting protein alpha-1) (LAR-interacting protein 1) (LIP.1).

LMBTL_HUMAN
θ value	4.03905 (rank : 53)	NC score	0.011776 (rank : 67)
Query Neighborhood Hits	73	Target Neighborhood Hits	70	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y468, Q5H8Y8, Q8IUV7, Q9H1E6, Q9H1G5, Q9UG06, Q9UJB9, Q9Y4C9	Gene names	L3MBTL, KIAA0681, L3MBT
Domain Architecture
Description	Lethal(3)malignant brain tumor-like protein (L(3)mbt-like) (L(3)mbt protein homolog) (H-l(3)mbt protein) (H-L(3)MBT) (L3MBTL1).

RBP24_HUMAN
θ value	4.03905 (rank : 54)	NC score	0.033367 (rank : 39)
Query Neighborhood Hits	73	Target Neighborhood Hits	1559	Shared Neighborhood Hits	48
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

RUFY2_MOUSE
θ value	4.03905 (rank : 55)	NC score	0.024202 (rank : 54)
Query Neighborhood Hits	73	Target Neighborhood Hits	820	Shared Neighborhood Hits	41
SwissProt Accessions	Q8R4C2, Q69ZH1	Gene names	Rufy2, Kiaa1537
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Leucine zipper FYVE-finger protein) (LZ-FYVE).

BFSP1_HUMAN
θ value	5.27518 (rank : 56)	NC score	0.021713 (rank : 61)
Query Neighborhood Hits	73	Target Neighborhood Hits	508	Shared Neighborhood Hits	33
SwissProt Accessions	Q12934, O43595, O76034, Q9HBX4	Gene names	BFSP1
Domain Architecture
Description	Filensin (Beaded filament structural protein 1) (Lens fiber cell beaded-filament structural protein CP 115) (CP115) (Lens intermediate filament-like heavy) (LIFL-H).

CO029_HUMAN
θ value	5.27518 (rank : 57)	NC score	0.011662 (rank : 68)
Query Neighborhood Hits	73	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H079, Q2TAC0, Q9H670	Gene names	C15orf29
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf29.

ROCK1_HUMAN
θ value	5.27518 (rank : 58)	NC score	0.010584 (rank : 70)
Query Neighborhood Hits	73	Target Neighborhood Hits	2000	Shared Neighborhood Hits	48
SwissProt Accessions	Q13464	Gene names	ROCK1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (NY-REN-35 antigen).

RUFY2_HUMAN
θ value	5.27518 (rank : 59)	NC score	0.024506 (rank : 52)
Query Neighborhood Hits	73	Target Neighborhood Hits	1208	Shared Neighborhood Hits	45
SwissProt Accessions	Q8WXA3, Q96P51, Q9P1Z1	Gene names	RUFY2, KIAA1537, RABIP4R
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related).

SH22A_HUMAN
θ value	5.27518 (rank : 60)	NC score	0.094669 (rank : 15)
Query Neighborhood Hits	73	Target Neighborhood Hits	144	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NP31, O43817, Q9UPA7	Gene names	SH2D2A, SCAP, TSAD, VRAP
Domain Architecture
Description	SH2 domain protein 2A (T cell-specific adapter protein) (TSAd) (VEGF receptor-associated protein) (SH2 domain-containing adapter protein).

ARHGA_HUMAN
θ value	6.88961 (rank : 61)	NC score	0.005206 (rank : 72)
Query Neighborhood Hits	73	Target Neighborhood Hits	187	Shared Neighborhood Hits	7
SwissProt Accessions	O15013, O14665, Q68D55, Q8IWD9, Q8IY77	Gene names	ARHGEF10, KIAA0294
Domain Architecture
Description	Rho guanine nucleotide exchange factor 10.

CT195_MOUSE
θ value	6.88961 (rank : 62)	NC score	0.018299 (rank : 63)
Query Neighborhood Hits	73	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	Q80WB0	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf195 homolog.

KIF5C_HUMAN
θ value	6.88961 (rank : 63)	NC score	0.023747 (rank : 55)
Query Neighborhood Hits	73	Target Neighborhood Hits	974	Shared Neighborhood Hits	43
SwissProt Accessions	O60282, O95079	Gene names	KIF5C, KIAA0531, NKHC2
Domain Architecture	No domain graphic available
Description	Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific 2).

MY18A_MOUSE
θ value	6.88961 (rank : 64)	NC score	0.023072 (rank : 59)
Query Neighborhood Hits	73	Target Neighborhood Hits	1989	Shared Neighborhood Hits	50
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

PARD3_HUMAN
θ value	6.88961 (rank : 65)	NC score	0.004564 (rank : 73)
Query Neighborhood Hits	73	Target Neighborhood Hits	312	Shared Neighborhood Hits	9
SwissProt Accessions	Q8TEW0, Q8TEW1, Q8TEW2, Q8TEW3, Q96K28, Q96RM6, Q96RM7, Q9BY57, Q9BY58, Q9HC48, Q9NWL4, Q9NYE6	Gene names	PARD3, PAR3, PAR3A
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2- 5) (PAR3-alpha).

PROX1_HUMAN
θ value	6.88961 (rank : 66)	NC score	0.022972 (rank : 60)
Query Neighborhood Hits	73	Target Neighborhood Hits	171	Shared Neighborhood Hits	22
SwissProt Accessions	Q92786, Q5SW76, Q8TB91	Gene names	PROX1
Domain Architecture
Description	Homeobox prospero-like protein PROX1 (PROX 1).

SH22A_MOUSE
θ value	6.88961 (rank : 67)	NC score	0.061914 (rank : 18)
Query Neighborhood Hits	73	Target Neighborhood Hits	179	Shared Neighborhood Hits	18
SwissProt Accessions	Q9QXK9, Q9JHP6	Gene names	Sh2d2a, Lad, Ribp
Domain Architecture
Description	SH2 domain protein 2A (Lck-associated adapter protein) (Lad) (Rlk/Itk- binding protein) (Ribp).

CCD46_HUMAN
θ value	8.99809 (rank : 68)	NC score	0.023411 (rank : 57)
Query Neighborhood Hits	73	Target Neighborhood Hits	1430	Shared Neighborhood Hits	46
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

DCAK2_MOUSE
θ value	8.99809 (rank : 69)	NC score	-0.003023 (rank : 74)
Query Neighborhood Hits	73	Target Neighborhood Hits	858	Shared Neighborhood Hits	3
SwissProt Accessions	Q6PGN3, Q8BUU0, Q8BX25	Gene names	Dcamkl2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase DCAMKL2 (EC 2.7.11.1) (Doublecortin- like and CAM kinase-like 2).

GOGB1_HUMAN
θ value	8.99809 (rank : 70)	NC score	0.051463 (rank : 19)
Query Neighborhood Hits	73	Target Neighborhood Hits	2297	Shared Neighborhood Hits	55
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

GRAP1_HUMAN
θ value	8.99809 (rank : 71)	NC score	0.021289 (rank : 62)
Query Neighborhood Hits	73	Target Neighborhood Hits	944	Shared Neighborhood Hits	40
SwissProt Accessions	Q4V328, Q4V327, Q4V330, Q5HYG1, Q6N046, Q96DH8, Q9NQ43, Q9ULQ3	Gene names	GRIPAP1, KIAA1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1).

HSH2D_HUMAN
θ value	8.99809 (rank : 72)	NC score	0.044191 (rank : 24)
Query Neighborhood Hits	73	Target Neighborhood Hits	159	Shared Neighborhood Hits	11
SwissProt Accessions	Q96JZ2, Q6ZNG7	Gene names	HSH2D, ALX
Domain Architecture	No domain graphic available
Description	Hematopoietic SH2 domain-containing protein (Hematopoietic SH2 protein) (Adaptor in lymphocytes of unknown function X).

MSRE_MOUSE
θ value	8.99809 (rank : 73)	NC score	0.009626 (rank : 71)
Query Neighborhood Hits	73	Target Neighborhood Hits	307	Shared Neighborhood Hits	20
SwissProt Accessions	P30204, Q923G0, Q9QZ56	Gene names	Msr1, Scvr
Domain Architecture
Description	Macrophage scavenger receptor types I and II (Macrophage acetylated LDL receptor I and II) (Scavenger receptor type A) (SR-A).

CCD27_MOUSE
θ value	θ > 10 (rank : 74)	NC score	0.051036 (rank : 20)
Query Neighborhood Hits	73	Target Neighborhood Hits	461	Shared Neighborhood Hits	37
SwissProt Accessions	Q3V036	Gene names	Ccdc27
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 27.

Hits sorted by NC score

STAT4_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 6)
Query Neighborhood Hits	73	Target Neighborhood Hits	73	Shared Neighborhood Hits	73
SwissProt Accessions	P42228	Gene names	Stat4
Domain Architecture
Description	Signal transducer and activator of transcription 4.

STAT4_HUMAN
NC score	0.991351 (rank : 2)	θ value	0 (rank : 5)
Query Neighborhood Hits	73	Target Neighborhood Hits	91	Shared Neighborhood Hits	46
SwissProt Accessions	Q14765, Q96NZ6	Gene names	STAT4
Domain Architecture
Description	Signal transducer and activator of transcription 4.

STAT1_HUMAN
NC score	0.976428 (rank : 3)	θ value	0 (rank : 1)
Query Neighborhood Hits	73	Target Neighborhood Hits	128	Shared Neighborhood Hits	33
SwissProt Accessions	P42224	Gene names	STAT1
Domain Architecture
Description	Signal transducer and activator of transcription 1-alpha/beta (Transcription factor ISGF-3 components p91/p84).

STAT1_MOUSE
NC score	0.973735 (rank : 4)	θ value	0 (rank : 2)
Query Neighborhood Hits	73	Target Neighborhood Hits	151	Shared Neighborhood Hits	33
SwissProt Accessions	P42225	Gene names	Stat1
Domain Architecture
Description	Signal transducer and activator of transcription 1.

STAT3_HUMAN
NC score	0.970319 (rank : 5)	θ value	0 (rank : 3)
Query Neighborhood Hits	73	Target Neighborhood Hits	155	Shared Neighborhood Hits	29
SwissProt Accessions	P40763, O14916, Q9BW54	Gene names	STAT3, APRF
Domain Architecture
Description	Signal transducer and activator of transcription 3 (Acute-phase response factor).

STAT3_MOUSE
NC score	0.970318 (rank : 6)	θ value	0 (rank : 4)
Query Neighborhood Hits	73	Target Neighborhood Hits	155	Shared Neighborhood Hits	29
SwissProt Accessions	P42227	Gene names	Stat3, Aprf
Domain Architecture
Description	Signal transducer and activator of transcription 3 (Acute-phase response factor).

STAT2_HUMAN
NC score	0.967100 (rank : 7)	θ value	8.37844e-131 (rank : 7)
Query Neighborhood Hits	73	Target Neighborhood Hits	99	Shared Neighborhood Hits	20
SwissProt Accessions	P52630, Q16430, Q16431	Gene names	STAT2
Domain Architecture
Description	Signal transducer and activator of transcription 2 (p113).

STAT2_MOUSE
NC score	0.918194 (rank : 8)	θ value	1.29561e-123 (rank : 8)
Query Neighborhood Hits	73	Target Neighborhood Hits	175	Shared Neighborhood Hits	16
SwissProt Accessions	Q9WVL2, Q64188, Q64189, Q64250	Gene names	Stat2
Domain Architecture
Description	Signal transducer and activator of transcription 2.

STA5B_HUMAN
NC score	0.902819 (rank : 9)	θ value	5.50685e-82 (rank : 10)
Query Neighborhood Hits	73	Target Neighborhood Hits	103	Shared Neighborhood Hits	28
SwissProt Accessions	P51692, Q8WWS8	Gene names	STAT5B
Domain Architecture
Description	Signal transducer and activator of transcription 5B.

STA5B_MOUSE
NC score	0.900733 (rank : 10)	θ value	1.18549e-84 (rank : 9)
Query Neighborhood Hits	73	Target Neighborhood Hits	124	Shared Neighborhood Hits	32
SwissProt Accessions	P42232, Q541Q5, Q60804, Q8K3Q1, Q9JKM1	Gene names	Stat5b
Domain Architecture
Description	Signal transducer and activator of transcription 5B.

STA5A_MOUSE
NC score	0.896843 (rank : 11)	θ value	3.69378e-78 (rank : 11)
Query Neighborhood Hits	73	Target Neighborhood Hits	128	Shared Neighborhood Hits	31
SwissProt Accessions	P42230	Gene names	Stat5a, Mgf, Mpf
Domain Architecture
Description	Signal transducer and activator of transcription 5A (Mammary gland factor).

STA5A_HUMAN
NC score	0.894557 (rank : 12)	θ value	4.51533e-76 (rank : 12)
Query Neighborhood Hits	73	Target Neighborhood Hits	140	Shared Neighborhood Hits	32
SwissProt Accessions	P42229	Gene names	STAT5A, STAT5
Domain Architecture
Description	Signal transducer and activator of transcription 5A.

STAT6_MOUSE
NC score	0.871283 (rank : 13)	θ value	1.01294e-51 (rank : 14)
Query Neighborhood Hits	73	Target Neighborhood Hits	78	Shared Neighborhood Hits	15
SwissProt Accessions	P52633	Gene names	Stat6
Domain Architecture
Description	Signal transducer and transcription activator 6.

STAT6_HUMAN
NC score	0.867572 (rank : 14)	θ value	1.41344e-53 (rank : 13)
Query Neighborhood Hits	73	Target Neighborhood Hits	132	Shared Neighborhood Hits	18
SwissProt Accessions	P42226	Gene names	STAT6
Domain Architecture
Description	Signal transducer and activator of transcription 6 (IL-4 Stat).

SH22A_HUMAN
NC score	0.094669 (rank : 15)	θ value	5.27518 (rank : 60)
Query Neighborhood Hits	73	Target Neighborhood Hits	144	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NP31, O43817, Q9UPA7	Gene names	SH2D2A, SCAP, TSAD, VRAP
Domain Architecture
Description	SH2 domain protein 2A (T cell-specific adapter protein) (TSAd) (VEGF receptor-associated protein) (SH2 domain-containing adapter protein).

HSH2D_MOUSE
NC score	0.065342 (rank : 16)	θ value	0.62314 (rank : 24)
Query Neighborhood Hits	73	Target Neighborhood Hits	124	Shared Neighborhood Hits	14
SwissProt Accessions	Q6VYH9, Q52KL3	Gene names	Hsh2d, Alx
Domain Architecture	No domain graphic available
Description	Hematopoietic SH2 domain-containing protein (Hematopoietic SH2 protein) (Adaptor in lymphocytes of unknown function X).

CCD27_HUMAN
NC score	0.065272 (rank : 17)	θ value	3.0926 (rank : 48)
Query Neighborhood Hits	73	Target Neighborhood Hits	594	Shared Neighborhood Hits	41
SwissProt Accessions	Q2M243, Q5TBV3, Q96M50	Gene names	CCDC27
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 27.

SH22A_MOUSE
NC score	0.061914 (rank : 18)	θ value	6.88961 (rank : 67)
Query Neighborhood Hits	73	Target Neighborhood Hits	179	Shared Neighborhood Hits	18
SwissProt Accessions	Q9QXK9, Q9JHP6	Gene names	Sh2d2a, Lad, Ribp
Domain Architecture
Description	SH2 domain protein 2A (Lck-associated adapter protein) (Lad) (Rlk/Itk- binding protein) (Ribp).

GOGB1_HUMAN
NC score	0.051463 (rank : 19)	θ value	8.99809 (rank : 70)
Query Neighborhood Hits	73	Target Neighborhood Hits	2297	Shared Neighborhood Hits	55
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

CCD27_MOUSE
NC score	0.051036 (rank : 20)	θ value	θ > 10 (rank : 74)
Query Neighborhood Hits	73	Target Neighborhood Hits	461	Shared Neighborhood Hits	37
SwissProt Accessions	Q3V036	Gene names	Ccdc27
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 27.

KTN1_HUMAN
NC score	0.049028 (rank : 21)	θ value	0.00228821 (rank : 15)
Query Neighborhood Hits	73	Target Neighborhood Hits	1197	Shared Neighborhood Hits	46
SwissProt Accessions	Q86UP2, Q13999, Q14707, Q15387, Q86W57	Gene names	KTN1, CG1, KIAA0004
Domain Architecture	No domain graphic available
Description	Kinectin (Kinesin receptor) (CG-1 antigen).

TRIPB_HUMAN
NC score	0.045875 (rank : 22)	θ value	0.813845 (rank : 33)
Query Neighborhood Hits	73	Target Neighborhood Hits	1587	Shared Neighborhood Hits	52
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

ADIP_MOUSE
NC score	0.045712 (rank : 23)	θ value	1.38821 (rank : 36)
Query Neighborhood Hits	73	Target Neighborhood Hits	415	Shared Neighborhood Hits	38
SwissProt Accessions	Q8VC66, Q8BG59, Q8C7X0, Q8K2F7	Gene names	Ssx2ip
Domain Architecture	No domain graphic available
Description	Afadin- and alpha-actinin-binding protein (ADIP) (Afadin DIL domain- interacting protein).

HSH2D_HUMAN
NC score	0.044191 (rank : 24)	θ value	8.99809 (rank : 72)
Query Neighborhood Hits	73	Target Neighborhood Hits	159	Shared Neighborhood Hits	11
SwissProt Accessions	Q96JZ2, Q6ZNG7	Gene names	HSH2D, ALX
Domain Architecture	No domain graphic available
Description	Hematopoietic SH2 domain-containing protein (Hematopoietic SH2 protein) (Adaptor in lymphocytes of unknown function X).

TPR_HUMAN
NC score	0.044123 (rank : 25)	θ value	2.36792 (rank : 47)
Query Neighborhood Hits	73	Target Neighborhood Hits	1921	Shared Neighborhood Hits	50
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

K0082_HUMAN
NC score	0.043849 (rank : 26)	θ value	0.813845 (rank : 27)
Query Neighborhood Hits	73	Target Neighborhood Hits	60	Shared Neighborhood Hits	4
SwissProt Accessions	Q8N1G2, Q14670, Q96FJ9	Gene names	KIAA0082
Domain Architecture	No domain graphic available
Description	Protein KIAA0082.

ADIP_HUMAN
NC score	0.043381 (rank : 27)	θ value	1.81305 (rank : 39)
Query Neighborhood Hits	73	Target Neighborhood Hits	470	Shared Neighborhood Hits	38
SwissProt Accessions	Q9Y2D8, Q6P2P8, Q6ULS1, Q7L168, Q9UIX0	Gene names	SSX2IP, KIAA0923
Domain Architecture	No domain graphic available
Description	Afadin- and alpha-actinin-binding protein (ADIP) (Afadin DIL domain- interacting protein) (SSX2-interacting protein).

K0082_MOUSE
NC score	0.042525 (rank : 28)	θ value	1.06291 (rank : 34)
Query Neighborhood Hits	73	Target Neighborhood Hits	62	Shared Neighborhood Hits	4
SwissProt Accessions	Q9DBC3, Q3U3G5, Q3U7Y9, Q6A0D5, Q8C7V0	Gene names	Kiaa0082
Domain Architecture	No domain graphic available
Description	Protein KIAA0082.

HMMR_HUMAN
NC score	0.042371 (rank : 29)	θ value	3.0926 (rank : 49)
Query Neighborhood Hits	73	Target Neighborhood Hits	1082	Shared Neighborhood Hits	49
SwissProt Accessions	O75330, Q92767	Gene names	HMMR, IHABP, RHAMM
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen).

GOGA4_MOUSE
NC score	0.041984 (rank : 30)	θ value	0.813845 (rank : 26)
Query Neighborhood Hits	73	Target Neighborhood Hits	1939	Shared Neighborhood Hits	55
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

BRE1A_HUMAN
NC score	0.040248 (rank : 31)	θ value	0.62314 (rank : 22)
Query Neighborhood Hits	73	Target Neighborhood Hits	1071	Shared Neighborhood Hits	45
SwissProt Accessions	Q5VTR2, Q69YL5, Q6P527, Q8N3J4, Q96JD3, Q9H9Y7, Q9HA51, Q9NUR4, Q9NWQ3, Q9NX83	Gene names	RNF20, BRE1A
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (hBRE1) (RING finger protein 20).

NIN_HUMAN
NC score	0.037361 (rank : 32)	θ value	0.163984 (rank : 16)
Query Neighborhood Hits	73	Target Neighborhood Hits	1416	Shared Neighborhood Hits	46
SwissProt Accessions	Q8N4C6, Q6P0P6, Q9BWU6, Q9C012, Q9C013, Q9C014, Q9H5I6, Q9HAT7, Q9HBY5, Q9HCK7, Q9UH61	Gene names	NIN, KIAA1565
Domain Architecture	No domain graphic available
Description	Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein).

CP135_MOUSE
NC score	0.036528 (rank : 33)	θ value	4.03905 (rank : 50)
Query Neighborhood Hits	73	Target Neighborhood Hits	1278	Shared Neighborhood Hits	48
SwissProt Accessions	Q6P5D4, Q6A030	Gene names	Cep135, Cep4, Kiaa0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

BRE1A_MOUSE
NC score	0.036524 (rank : 34)	θ value	0.62314 (rank : 23)
Query Neighborhood Hits	73	Target Neighborhood Hits	1025	Shared Neighborhood Hits	45
SwissProt Accessions	Q5DTM8, Q3UT10, Q3V350, Q7TT11, Q8BKA8, Q8BKN8, Q8BUF7, Q8BVU4	Gene names	Rnf20, Bre1a, Kiaa4116
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (RING finger protein 20).

UGGG2_HUMAN
NC score	0.034903 (rank : 35)	θ value	0.163984 (rank : 17)
Query Neighborhood Hits	73	Target Neighborhood Hits	32	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NYU1, Q9UFC4	Gene names	UGCGL2, UGT2
Domain Architecture
Description	UDP-glucose:glycoprotein glucosyltransferase 2 precursor (EC 2.4.1.-) (UDP-glucose ceramide glucosyltransferase-like 1) (UDP-- Glc:glycoprotein glucosyltransferase 2) (HUGT2).

CCD91_HUMAN
NC score	0.034162 (rank : 36)	θ value	2.36792 (rank : 44)
Query Neighborhood Hits	73	Target Neighborhood Hits	868	Shared Neighborhood Hits	38
SwissProt Accessions	Q7Z6B0, Q68D43, Q6IA78, Q8NEN7, Q9NUW9	Gene names	CCDC91, GGABP
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner) (p56 accessory protein).

GOGA5_MOUSE
NC score	0.033823 (rank : 37)	θ value	0.279714 (rank : 19)
Query Neighborhood Hits	73	Target Neighborhood Hits	1434	Shared Neighborhood Hits	47
SwissProt Accessions	Q9QYE6, O88317, Q3TGE7, Q3U6S5, Q3UUF9	Gene names	Golga5, Retii
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (Sumiko protein) (Ret-II protein).

GCC2_HUMAN
NC score	0.033594 (rank : 38)	θ value	1.81305 (rank : 41)
Query Neighborhood Hits	73	Target Neighborhood Hits	1558	Shared Neighborhood Hits	47
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

RBP24_HUMAN
NC score	0.033367 (rank : 39)	θ value	4.03905 (rank : 54)
Query Neighborhood Hits	73	Target Neighborhood Hits	1559	Shared Neighborhood Hits	48
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

EP15_HUMAN
NC score	0.033163 (rank : 40)	θ value	1.81305 (rank : 40)
Query Neighborhood Hits	73	Target Neighborhood Hits	1021	Shared Neighborhood Hits	45
SwissProt Accessions	P42566	Gene names	EPS15, AF1P
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

PCNT_MOUSE
NC score	0.033102 (rank : 41)	θ value	0.813845 (rank : 30)
Query Neighborhood Hits	73	Target Neighborhood Hits	1207	Shared Neighborhood Hits	45
SwissProt Accessions	P48725	Gene names	Pcnt, Pcnt2
Domain Architecture	No domain graphic available
Description	Pericentrin.

HMMR_MOUSE
NC score	0.032337 (rank : 42)	θ value	0.21417 (rank : 18)
Query Neighborhood Hits	73	Target Neighborhood Hits	1178	Shared Neighborhood Hits	45
SwissProt Accessions	Q00547	Gene names	Hmmr, Ihabp, Rhamm
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility).

GOGA5_HUMAN
NC score	0.031665 (rank : 43)	θ value	1.81305 (rank : 42)
Query Neighborhood Hits	73	Target Neighborhood Hits	1168	Shared Neighborhood Hits	43
SwissProt Accessions	Q8TBA6, O95287, Q03962, Q9UQQ7	Gene names	GOLGA5, RETII, RFG5
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (RET-fused gene 5 protein) (Ret-II protein).

CT096_HUMAN
NC score	0.031164 (rank : 44)	θ value	2.36792 (rank : 45)
Query Neighborhood Hits	73	Target Neighborhood Hits	438	Shared Neighborhood Hits	37
SwissProt Accessions	Q9NUD7, Q8N840, Q8NAX5	Gene names	C20orf96
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf96.

CAR11_HUMAN
NC score	0.030379 (rank : 45)	θ value	0.47712 (rank : 20)
Query Neighborhood Hits	73	Target Neighborhood Hits	690	Shared Neighborhood Hits	41
SwissProt Accessions	Q9BXL7, Q548H3	Gene names	CARD11, CARMA1
Domain Architecture
Description	Caspase recruitment domain-containing protein 11 (CARD-containing MAGUK protein 3) (Carma 1).

UACA_MOUSE
NC score	0.028676 (rank : 46)	θ value	1.06291 (rank : 35)
Query Neighborhood Hits	73	Target Neighborhood Hits	1620	Shared Neighborhood Hits	45
SwissProt Accessions	Q8CGB3, Q69ZG3, Q7TN77, Q8BJC8	Gene names	Uaca, Kiaa1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein (Nucling) (Nuclear membrane-binding protein).

SYAP1_HUMAN
NC score	0.027971 (rank : 47)	θ value	1.38821 (rank : 37)
Query Neighborhood Hits	73	Target Neighborhood Hits	58	Shared Neighborhood Hits	9
SwissProt Accessions	Q96A49, Q96C60, Q96JQ6, Q96T20	Gene names	SYAP1
Domain Architecture
Description	Synapse-associated protein 1.

UACA_HUMAN
NC score	0.027654 (rank : 48)	θ value	0.47712 (rank : 21)
Query Neighborhood Hits	73	Target Neighborhood Hits	1622	Shared Neighborhood Hits	46
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

LIPA1_HUMAN
NC score	0.027190 (rank : 49)	θ value	4.03905 (rank : 52)
Query Neighborhood Hits	73	Target Neighborhood Hits	1294	Shared Neighborhood Hits	42
SwissProt Accessions	Q13136, Q13135, Q14567, Q8N4I2	Gene names	PPFIA1, LIP1
Domain Architecture
Description	Liprin-alpha-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1) (PTPRF-interacting protein alpha-1) (LAR-interacting protein 1) (LIP.1).

PROX1_MOUSE
NC score	0.026593 (rank : 50)	θ value	2.36792 (rank : 46)
Query Neighborhood Hits	73	Target Neighborhood Hits	184	Shared Neighborhood Hits	24
SwissProt Accessions	P48437, O88478, Q3UPV1, Q543D8	Gene names	Prox1
Domain Architecture
Description	Homeobox prospero-like protein PROX1 (PROX 1).

LRC45_HUMAN
NC score	0.025550 (rank : 51)	θ value	0.62314 (rank : 25)
Query Neighborhood Hits	73	Target Neighborhood Hits	933	Shared Neighborhood Hits	38
SwissProt Accessions	Q96CN5	Gene names	LRRC45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

RUFY2_HUMAN
NC score	0.024506 (rank : 52)	θ value	5.27518 (rank : 59)
Query Neighborhood Hits	73	Target Neighborhood Hits	1208	Shared Neighborhood Hits	45
SwissProt Accessions	Q8WXA3, Q96P51, Q9P1Z1	Gene names	RUFY2, KIAA1537, RABIP4R
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related).

LRSM1_HUMAN
NC score	0.024456 (rank : 53)	θ value	1.81305 (rank : 43)
Query Neighborhood Hits	73	Target Neighborhood Hits	1078	Shared Neighborhood Hits	45
SwissProt Accessions	Q6UWE0, Q5VVV0, Q8NB40, Q96GT5, Q96MX5, Q96MZ7	Gene names	LRSAM1, TAL
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) (hTAL).

RUFY2_MOUSE
NC score	0.024202 (rank : 54)	θ value	4.03905 (rank : 55)
Query Neighborhood Hits	73	Target Neighborhood Hits	820	Shared Neighborhood Hits	41
SwissProt Accessions	Q8R4C2, Q69ZH1	Gene names	Rufy2, Kiaa1537
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Leucine zipper FYVE-finger protein) (LZ-FYVE).

KIF5C_HUMAN
NC score	0.023747 (rank : 55)	θ value	6.88961 (rank : 63)
Query Neighborhood Hits	73	Target Neighborhood Hits	974	Shared Neighborhood Hits	43
SwissProt Accessions	O60282, O95079	Gene names	KIF5C, KIAA0531, NKHC2
Domain Architecture	No domain graphic available
Description	Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific 2).

SYNE2_HUMAN
NC score	0.023596 (rank : 56)	θ value	1.38821 (rank : 38)
Query Neighborhood Hits	73	Target Neighborhood Hits	1323	Shared Neighborhood Hits	41
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

CCD46_HUMAN
NC score	0.023411 (rank : 57)	θ value	8.99809 (rank : 68)
Query Neighborhood Hits	73	Target Neighborhood Hits	1430	Shared Neighborhood Hits	46
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

MYH11_HUMAN
NC score	0.023229 (rank : 58)	θ value	0.813845 (rank : 29)
Query Neighborhood Hits	73	Target Neighborhood Hits	1806	Shared Neighborhood Hits	47
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

MY18A_MOUSE
NC score	0.023072 (rank : 59)	θ value	6.88961 (rank : 64)
Query Neighborhood Hits	73	Target Neighborhood Hits	1989	Shared Neighborhood Hits	50
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

PROX1_HUMAN
NC score	0.022972 (rank : 60)	θ value	6.88961 (rank : 66)
Query Neighborhood Hits	73	Target Neighborhood Hits	171	Shared Neighborhood Hits	22
SwissProt Accessions	Q92786, Q5SW76, Q8TB91	Gene names	PROX1
Domain Architecture
Description	Homeobox prospero-like protein PROX1 (PROX 1).

BFSP1_HUMAN
NC score	0.021713 (rank : 61)	θ value	5.27518 (rank : 56)
Query Neighborhood Hits	73	Target Neighborhood Hits	508	Shared Neighborhood Hits	33
SwissProt Accessions	Q12934, O43595, O76034, Q9HBX4	Gene names	BFSP1
Domain Architecture
Description	Filensin (Beaded filament structural protein 1) (Lens fiber cell beaded-filament structural protein CP 115) (CP115) (Lens intermediate filament-like heavy) (LIFL-H).

GRAP1_HUMAN
NC score	0.021289 (rank : 62)	θ value	8.99809 (rank : 71)
Query Neighborhood Hits	73	Target Neighborhood Hits	944	Shared Neighborhood Hits	40
SwissProt Accessions	Q4V328, Q4V327, Q4V330, Q5HYG1, Q6N046, Q96DH8, Q9NQ43, Q9ULQ3	Gene names	GRIPAP1, KIAA1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1).

CT195_MOUSE
NC score	0.018299 (rank : 63)	θ value	6.88961 (rank : 62)
Query Neighborhood Hits	73	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	Q80WB0	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf195 homolog.

K2C1_HUMAN
NC score	0.016368 (rank : 64)	θ value	0.813845 (rank : 28)
Query Neighborhood Hits	73	Target Neighborhood Hits	624	Shared Neighborhood Hits	38
SwissProt Accessions	P04264, Q14720, Q6GSJ0, Q9H298	Gene names	KRT1, KRTA
Domain Architecture
Description	Keratin, type II cytoskeletal 1 (Cytokeratin-1) (CK-1) (Keratin-1) (K1) (67 kDa cytokeratin) (Hair alpha protein).

PTN11_HUMAN
NC score	0.012435 (rank : 65)	θ value	0.813845 (rank : 31)
Query Neighborhood Hits	73	Target Neighborhood Hits	227	Shared Neighborhood Hits	9
SwissProt Accessions	Q06124, Q96HD7	Gene names	PTPN11, PTP2C, SHPTP2
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase 2C) (PTP-2C) (PTP-1D) (SH-PTP3) (SH- PTP2) (SHP-2) (Shp2).

PTN11_MOUSE
NC score	0.012412 (rank : 66)	θ value	0.813845 (rank : 32)
Query Neighborhood Hits	73	Target Neighborhood Hits	227	Shared Neighborhood Hits	8
SwissProt Accessions	P35235, Q3TQ84, Q64509, Q6PCL5	Gene names	Ptpn11
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase SYP) (SH-PTP2) (SHP-2) (Shp2).

LMBTL_HUMAN
NC score	0.011776 (rank : 67)	θ value	4.03905 (rank : 53)
Query Neighborhood Hits	73	Target Neighborhood Hits	70	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y468, Q5H8Y8, Q8IUV7, Q9H1E6, Q9H1G5, Q9UG06, Q9UJB9, Q9Y4C9	Gene names	L3MBTL, KIAA0681, L3MBT
Domain Architecture
Description	Lethal(3)malignant brain tumor-like protein (L(3)mbt-like) (L(3)mbt protein homolog) (H-l(3)mbt protein) (H-L(3)MBT) (L3MBTL1).

CO029_HUMAN
NC score	0.011662 (rank : 68)	θ value	5.27518 (rank : 57)
Query Neighborhood Hits	73	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H079, Q2TAC0, Q9H670	Gene names	C15orf29
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf29.

IRS2_MOUSE
NC score	0.010949 (rank : 69)	θ value	4.03905 (rank : 51)
Query Neighborhood Hits	73	Target Neighborhood Hits	248	Shared Neighborhood Hits	3
SwissProt Accessions	P81122	Gene names	Irs2
Domain Architecture	No domain graphic available
Description	Insulin receptor substrate 2 (IRS-2) (4PS).

ROCK1_HUMAN
NC score	0.010584 (rank : 70)	θ value	5.27518 (rank : 58)
Query Neighborhood Hits	73	Target Neighborhood Hits	2000	Shared Neighborhood Hits	48
SwissProt Accessions	Q13464	Gene names	ROCK1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (NY-REN-35 antigen).

MSRE_MOUSE
NC score	0.009626 (rank : 71)	θ value	8.99809 (rank : 73)
Query Neighborhood Hits	73	Target Neighborhood Hits	307	Shared Neighborhood Hits	20
SwissProt Accessions	P30204, Q923G0, Q9QZ56	Gene names	Msr1, Scvr
Domain Architecture
Description	Macrophage scavenger receptor types I and II (Macrophage acetylated LDL receptor I and II) (Scavenger receptor type A) (SR-A).

ARHGA_HUMAN
NC score	0.005206 (rank : 72)	θ value	6.88961 (rank : 61)
Query Neighborhood Hits	73	Target Neighborhood Hits	187	Shared Neighborhood Hits	7
SwissProt Accessions	O15013, O14665, Q68D55, Q8IWD9, Q8IY77	Gene names	ARHGEF10, KIAA0294
Domain Architecture
Description	Rho guanine nucleotide exchange factor 10.

PARD3_HUMAN
NC score	0.004564 (rank : 73)	θ value	6.88961 (rank : 65)
Query Neighborhood Hits	73	Target Neighborhood Hits	312	Shared Neighborhood Hits	9
SwissProt Accessions	Q8TEW0, Q8TEW1, Q8TEW2, Q8TEW3, Q96K28, Q96RM6, Q96RM7, Q9BY57, Q9BY58, Q9HC48, Q9NWL4, Q9NYE6	Gene names	PARD3, PAR3, PAR3A
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2- 5) (PAR3-alpha).

DCAK2_MOUSE
NC score	-0.003023 (rank : 74)	θ value	8.99809 (rank : 69)
Query Neighborhood Hits	73	Target Neighborhood Hits	858	Shared Neighborhood Hits	3
SwissProt Accessions	Q6PGN3, Q8BUU0, Q8BX25	Gene names	Dcamkl2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase DCAMKL2 (EC 2.7.11.1) (Doublecortin- like and CAM kinase-like 2).