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Network neighborhood for query Sequence : SC5A5_MOUSE

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SC5A5_MOUSE
SwissProt Accessions	Q99PN0	Gene names	Slc5a5, Nis
Domain Architecture	No domain graphic available
Description	Sodium/iodide cotransporter (Na(+)/I(-) cotransporter) (Sodium-iodide symporter) (Na(+)/I(-)-symporter).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SC5A5_HUMAN
θ value	0 (rank : 1)	NC score	0.996591 (rank : 2)
Query Neighborhood Hits	23	Target Neighborhood Hits	22	Shared Neighborhood Hits	15
SwissProt Accessions	Q92911, O43702, Q9NYB6	Gene names	SLC5A5, NIS
Domain Architecture
Description	Sodium/iodide cotransporter (Na(+)/I(-) cotransporter) (Sodium-iodide symporter) (Na(+)/I(-)-symporter).

SC5A5_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	23	Target Neighborhood Hits	23	Shared Neighborhood Hits	23
SwissProt Accessions	Q99PN0	Gene names	Slc5a5, Nis
Domain Architecture	No domain graphic available
Description	Sodium/iodide cotransporter (Na(+)/I(-) cotransporter) (Sodium-iodide symporter) (Na(+)/I(-)-symporter).

SC5A6_MOUSE
θ value	1.17455e-116 (rank : 3)	NC score	0.961430 (rank : 4)
Query Neighborhood Hits	23	Target Neighborhood Hits	16	Shared Neighborhood Hits	14
SwissProt Accessions	Q5U4D8	Gene names	Slc5a6
Domain Architecture	No domain graphic available
Description	Sodium-dependent multivitamin transporter (Na(+)-dependent multivitamin transporter).

SC5A6_HUMAN
θ value	4.4633e-116 (rank : 4)	NC score	0.962260 (rank : 3)
Query Neighborhood Hits	23	Target Neighborhood Hits	28	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y289	Gene names	SLC5A6, SMVT
Domain Architecture
Description	Sodium-dependent multivitamin transporter (Na(+)-dependent multivitamin transporter).

SC5A2_HUMAN
θ value	4.15078e-21 (rank : 5)	NC score	0.672410 (rank : 7)
Query Neighborhood Hits	23	Target Neighborhood Hits	20	Shared Neighborhood Hits	14
SwissProt Accessions	P31639	Gene names	SLC5A2, SGLT2
Domain Architecture
Description	Sodium/glucose cotransporter 2 (Na(+)/glucose cotransporter 2) (Low affinity sodium-glucose cotransporter).

SC5A2_MOUSE
θ value	7.0802e-21 (rank : 6)	NC score	0.665615 (rank : 10)
Query Neighborhood Hits	23	Target Neighborhood Hits	18	Shared Neighborhood Hits	14
SwissProt Accessions	Q923I7	Gene names	Slc5a2, Sglt2
Domain Architecture	No domain graphic available
Description	Sodium/glucose cotransporter 2 (Na(+)/glucose cotransporter 2) (Low affinity sodium-glucose cotransporter).

SC5A4_MOUSE
θ value	4.58923e-20 (rank : 7)	NC score	0.681117 (rank : 5)
Query Neighborhood Hits	23	Target Neighborhood Hits	32	Shared Neighborhood Hits	14
SwissProt Accessions	Q9ET37	Gene names	Slc5a4a
Domain Architecture
Description	Low affinity sodium-glucose cotransporter (Sodium/glucose cotransporter 3) (Na(+)/glucose cotransporter 3).

SC5A4_HUMAN
θ value	1.74391e-19 (rank : 8)	NC score	0.678037 (rank : 6)
Query Neighborhood Hits	23	Target Neighborhood Hits	26	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NY91, O15279	Gene names	SLC5A4, SAAT1, SGLT2
Domain Architecture
Description	Low affinity sodium-glucose cotransporter (Sodium/glucose cotransporter 3) (Na(+)/glucose cotransporter 3).

SC5A3_MOUSE
θ value	1.47631e-18 (rank : 9)	NC score	0.669532 (rank : 8)
Query Neighborhood Hits	23	Target Neighborhood Hits	29	Shared Neighborhood Hits	14
SwissProt Accessions	Q9JKZ2	Gene names	Slc5a3
Domain Architecture
Description	Sodium/myo-inositol cotransporter (Na(+)/myo-inositol cotransporter).

SC5A3_HUMAN
θ value	4.29542e-18 (rank : 10)	NC score	0.661234 (rank : 12)
Query Neighborhood Hits	23	Target Neighborhood Hits	35	Shared Neighborhood Hits	14
SwissProt Accessions	P53794, O43489	Gene names	SLC5A3
Domain Architecture
Description	Sodium/myo-inositol cotransporter (Na(+)/myo-inositol cotransporter).

SC5A1_HUMAN
θ value	7.32683e-18 (rank : 11)	NC score	0.666237 (rank : 9)
Query Neighborhood Hits	23	Target Neighborhood Hits	20	Shared Neighborhood Hits	14
SwissProt Accessions	P13866	Gene names	SLC5A1, NAGT, SGLT1
Domain Architecture
Description	Sodium/glucose cotransporter 1 (Na(+)/glucose cotransporter 1) (High affinity sodium-glucose cotransporter).

SC5A1_MOUSE
θ value	1.80466e-16 (rank : 12)	NC score	0.665431 (rank : 11)
Query Neighborhood Hits	23	Target Neighborhood Hits	24	Shared Neighborhood Hits	14
SwissProt Accessions	Q8C3K6	Gene names	Slc5a1
Domain Architecture	No domain graphic available
Description	Sodium/glucose cotransporter 1 (Na(+)/glucose cotransporter 1) (High affinity sodium-glucose cotransporter).

SC5A7_HUMAN
θ value	5.26297e-08 (rank : 13)	NC score	0.500829 (rank : 13)
Query Neighborhood Hits	23	Target Neighborhood Hits	16	Shared Neighborhood Hits	14
SwissProt Accessions	Q9GZV3	Gene names	SLC5A7, CHT1
Domain Architecture	No domain graphic available
Description	High-affinity choline transporter 1 (Solute carrier family 5 member 7) (Hemicholinium-3-sensitive choline transporter) (CHT).

SC5A7_MOUSE
θ value	9.29e-05 (rank : 14)	NC score	0.465383 (rank : 14)
Query Neighborhood Hits	23	Target Neighborhood Hits	16	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BGY9, Q99PK3, Q9ESW5	Gene names	Slc5a7, Cht1
Domain Architecture	No domain graphic available
Description	High-affinity choline transporter 1 (Solute carrier family 5 member 7) (Hemicholinium-3-sensitive choline transporter) (CHT).

PGCA_HUMAN
θ value	0.365318 (rank : 15)	NC score	0.012261 (rank : 16)
Query Neighborhood Hits	23	Target Neighborhood Hits	821	Shared Neighborhood Hits	4
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

GP120_HUMAN
θ value	3.0926 (rank : 16)	NC score	0.007858 (rank : 20)
Query Neighborhood Hits	23	Target Neighborhood Hits	458	Shared Neighborhood Hits	3
SwissProt Accessions	Q5NUL3, Q5VY25, Q5VY26, Q7Z605, Q86SM7	Gene names	GPR120, GPR129, PGR4
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 120 (G-protein coupled receptor PGR4) (G- protein coupled receptor GT01) (G-protein coupled receptor 129).

NPAS3_MOUSE
θ value	4.03905 (rank : 17)	NC score	0.008755 (rank : 19)
Query Neighborhood Hits	23	Target Neighborhood Hits	103	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QZQ0, Q9EQP4	Gene names	Npas3
Domain Architecture
Description	Neuronal PAS domain-containing protein 3 (Neuronal PAS3) (Member of PAS protein 6) (MOP6).

ADRM1_HUMAN
θ value	5.27518 (rank : 18)	NC score	0.019390 (rank : 15)
Query Neighborhood Hits	23	Target Neighborhood Hits	81	Shared Neighborhood Hits	4
SwissProt Accessions	Q16186, Q9H1P2	Gene names	ADRM1, GP110
Domain Architecture
Description	Adhesion-regulating molecule 1 precursor (110 kDa cell membrane glycoprotein) (Gp110).

DPOLM_HUMAN
θ value	6.88961 (rank : 19)	NC score	0.009784 (rank : 18)
Query Neighborhood Hits	23	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NP87	Gene names	POLM
Domain Architecture
Description	DNA polymerase mu (EC 2.7.7.7) (Pol Mu).

ACD_HUMAN
θ value	8.99809 (rank : 20)	NC score	0.011492 (rank : 17)
Query Neighborhood Hits	23	Target Neighborhood Hits	143	Shared Neighborhood Hits	3
SwissProt Accessions	Q96AP0, Q562H5, Q9H8F9	Gene names	ACD, PIP1, PTOP
Domain Architecture	No domain graphic available
Description	Adrenocortical dysplasia protein homolog (POT1 and TIN2-interacting protein).

KS6A3_HUMAN
θ value	8.99809 (rank : 21)	NC score	-0.001193 (rank : 22)
Query Neighborhood Hits	23	Target Neighborhood Hits	859	Shared Neighborhood Hits	3
SwissProt Accessions	P51812, Q4VAP3, Q59H26, Q5JPK8, Q7Z3Z7	Gene names	RPS6KA3, ISPK1, RSK2
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-3 (EC 2.7.11.1) (S6K-alpha 3) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2) (Insulin-stimulated protein kinase 1) (ISPK-1) (MAP kinase-activated protein kinase 1b) (MAPKAPK1B).

KS6A3_MOUSE
θ value	8.99809 (rank : 22)	NC score	-0.001193 (rank : 23)
Query Neighborhood Hits	23	Target Neighborhood Hits	860	Shared Neighborhood Hits	3
SwissProt Accessions	P18654, Q03140, Q8K3J8	Gene names	Rps6ka3, Rps6ka-rs1, Rsk2
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-3 (EC 2.7.11.1) (S6K-alpha 3) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2) (MAP kinase-activated protein kinase 1b) (MAPKAPK1B).

NACAM_MOUSE
θ value	8.99809 (rank : 23)	NC score	0.001529 (rank : 21)
Query Neighborhood Hits	23	Target Neighborhood Hits	1866	Shared Neighborhood Hits	5
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

Hits sorted by NC score

SC5A5_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	23	Target Neighborhood Hits	23	Shared Neighborhood Hits	23
SwissProt Accessions	Q99PN0	Gene names	Slc5a5, Nis
Domain Architecture	No domain graphic available
Description	Sodium/iodide cotransporter (Na(+)/I(-) cotransporter) (Sodium-iodide symporter) (Na(+)/I(-)-symporter).

SC5A5_HUMAN
NC score	0.996591 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	23	Target Neighborhood Hits	22	Shared Neighborhood Hits	15
SwissProt Accessions	Q92911, O43702, Q9NYB6	Gene names	SLC5A5, NIS
Domain Architecture
Description	Sodium/iodide cotransporter (Na(+)/I(-) cotransporter) (Sodium-iodide symporter) (Na(+)/I(-)-symporter).

SC5A6_HUMAN
NC score	0.962260 (rank : 3)	θ value	4.4633e-116 (rank : 4)
Query Neighborhood Hits	23	Target Neighborhood Hits	28	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y289	Gene names	SLC5A6, SMVT
Domain Architecture
Description	Sodium-dependent multivitamin transporter (Na(+)-dependent multivitamin transporter).

SC5A6_MOUSE
NC score	0.961430 (rank : 4)	θ value	1.17455e-116 (rank : 3)
Query Neighborhood Hits	23	Target Neighborhood Hits	16	Shared Neighborhood Hits	14
SwissProt Accessions	Q5U4D8	Gene names	Slc5a6
Domain Architecture	No domain graphic available
Description	Sodium-dependent multivitamin transporter (Na(+)-dependent multivitamin transporter).

SC5A4_MOUSE
NC score	0.681117 (rank : 5)	θ value	4.58923e-20 (rank : 7)
Query Neighborhood Hits	23	Target Neighborhood Hits	32	Shared Neighborhood Hits	14
SwissProt Accessions	Q9ET37	Gene names	Slc5a4a
Domain Architecture
Description	Low affinity sodium-glucose cotransporter (Sodium/glucose cotransporter 3) (Na(+)/glucose cotransporter 3).

SC5A4_HUMAN
NC score	0.678037 (rank : 6)	θ value	1.74391e-19 (rank : 8)
Query Neighborhood Hits	23	Target Neighborhood Hits	26	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NY91, O15279	Gene names	SLC5A4, SAAT1, SGLT2
Domain Architecture
Description	Low affinity sodium-glucose cotransporter (Sodium/glucose cotransporter 3) (Na(+)/glucose cotransporter 3).

SC5A2_HUMAN
NC score	0.672410 (rank : 7)	θ value	4.15078e-21 (rank : 5)
Query Neighborhood Hits	23	Target Neighborhood Hits	20	Shared Neighborhood Hits	14
SwissProt Accessions	P31639	Gene names	SLC5A2, SGLT2
Domain Architecture
Description	Sodium/glucose cotransporter 2 (Na(+)/glucose cotransporter 2) (Low affinity sodium-glucose cotransporter).

SC5A3_MOUSE
NC score	0.669532 (rank : 8)	θ value	1.47631e-18 (rank : 9)
Query Neighborhood Hits	23	Target Neighborhood Hits	29	Shared Neighborhood Hits	14
SwissProt Accessions	Q9JKZ2	Gene names	Slc5a3
Domain Architecture
Description	Sodium/myo-inositol cotransporter (Na(+)/myo-inositol cotransporter).

SC5A1_HUMAN
NC score	0.666237 (rank : 9)	θ value	7.32683e-18 (rank : 11)
Query Neighborhood Hits	23	Target Neighborhood Hits	20	Shared Neighborhood Hits	14
SwissProt Accessions	P13866	Gene names	SLC5A1, NAGT, SGLT1
Domain Architecture
Description	Sodium/glucose cotransporter 1 (Na(+)/glucose cotransporter 1) (High affinity sodium-glucose cotransporter).

SC5A2_MOUSE
NC score	0.665615 (rank : 10)	θ value	7.0802e-21 (rank : 6)
Query Neighborhood Hits	23	Target Neighborhood Hits	18	Shared Neighborhood Hits	14
SwissProt Accessions	Q923I7	Gene names	Slc5a2, Sglt2
Domain Architecture	No domain graphic available
Description	Sodium/glucose cotransporter 2 (Na(+)/glucose cotransporter 2) (Low affinity sodium-glucose cotransporter).

SC5A1_MOUSE
NC score	0.665431 (rank : 11)	θ value	1.80466e-16 (rank : 12)
Query Neighborhood Hits	23	Target Neighborhood Hits	24	Shared Neighborhood Hits	14
SwissProt Accessions	Q8C3K6	Gene names	Slc5a1
Domain Architecture	No domain graphic available
Description	Sodium/glucose cotransporter 1 (Na(+)/glucose cotransporter 1) (High affinity sodium-glucose cotransporter).

SC5A3_HUMAN
NC score	0.661234 (rank : 12)	θ value	4.29542e-18 (rank : 10)
Query Neighborhood Hits	23	Target Neighborhood Hits	35	Shared Neighborhood Hits	14
SwissProt Accessions	P53794, O43489	Gene names	SLC5A3
Domain Architecture
Description	Sodium/myo-inositol cotransporter (Na(+)/myo-inositol cotransporter).

SC5A7_HUMAN
NC score	0.500829 (rank : 13)	θ value	5.26297e-08 (rank : 13)
Query Neighborhood Hits	23	Target Neighborhood Hits	16	Shared Neighborhood Hits	14
SwissProt Accessions	Q9GZV3	Gene names	SLC5A7, CHT1
Domain Architecture	No domain graphic available
Description	High-affinity choline transporter 1 (Solute carrier family 5 member 7) (Hemicholinium-3-sensitive choline transporter) (CHT).

SC5A7_MOUSE
NC score	0.465383 (rank : 14)	θ value	9.29e-05 (rank : 14)
Query Neighborhood Hits	23	Target Neighborhood Hits	16	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BGY9, Q99PK3, Q9ESW5	Gene names	Slc5a7, Cht1
Domain Architecture	No domain graphic available
Description	High-affinity choline transporter 1 (Solute carrier family 5 member 7) (Hemicholinium-3-sensitive choline transporter) (CHT).

ADRM1_HUMAN
NC score	0.019390 (rank : 15)	θ value	5.27518 (rank : 18)
Query Neighborhood Hits	23	Target Neighborhood Hits	81	Shared Neighborhood Hits	4
SwissProt Accessions	Q16186, Q9H1P2	Gene names	ADRM1, GP110
Domain Architecture
Description	Adhesion-regulating molecule 1 precursor (110 kDa cell membrane glycoprotein) (Gp110).

PGCA_HUMAN
NC score	0.012261 (rank : 16)	θ value	0.365318 (rank : 15)
Query Neighborhood Hits	23	Target Neighborhood Hits	821	Shared Neighborhood Hits	4
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

ACD_HUMAN
NC score	0.011492 (rank : 17)	θ value	8.99809 (rank : 20)
Query Neighborhood Hits	23	Target Neighborhood Hits	143	Shared Neighborhood Hits	3
SwissProt Accessions	Q96AP0, Q562H5, Q9H8F9	Gene names	ACD, PIP1, PTOP
Domain Architecture	No domain graphic available
Description	Adrenocortical dysplasia protein homolog (POT1 and TIN2-interacting protein).

DPOLM_HUMAN
NC score	0.009784 (rank : 18)	θ value	6.88961 (rank : 19)
Query Neighborhood Hits	23	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NP87	Gene names	POLM
Domain Architecture
Description	DNA polymerase mu (EC 2.7.7.7) (Pol Mu).

NPAS3_MOUSE
NC score	0.008755 (rank : 19)	θ value	4.03905 (rank : 17)
Query Neighborhood Hits	23	Target Neighborhood Hits	103	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QZQ0, Q9EQP4	Gene names	Npas3
Domain Architecture
Description	Neuronal PAS domain-containing protein 3 (Neuronal PAS3) (Member of PAS protein 6) (MOP6).

GP120_HUMAN
NC score	0.007858 (rank : 20)	θ value	3.0926 (rank : 16)
Query Neighborhood Hits	23	Target Neighborhood Hits	458	Shared Neighborhood Hits	3
SwissProt Accessions	Q5NUL3, Q5VY25, Q5VY26, Q7Z605, Q86SM7	Gene names	GPR120, GPR129, PGR4
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 120 (G-protein coupled receptor PGR4) (G- protein coupled receptor GT01) (G-protein coupled receptor 129).

NACAM_MOUSE
NC score	0.001529 (rank : 21)	θ value	8.99809 (rank : 23)
Query Neighborhood Hits	23	Target Neighborhood Hits	1866	Shared Neighborhood Hits	5
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

KS6A3_HUMAN
NC score	-0.001193 (rank : 22)	θ value	8.99809 (rank : 21)
Query Neighborhood Hits	23	Target Neighborhood Hits	859	Shared Neighborhood Hits	3
SwissProt Accessions	P51812, Q4VAP3, Q59H26, Q5JPK8, Q7Z3Z7	Gene names	RPS6KA3, ISPK1, RSK2
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-3 (EC 2.7.11.1) (S6K-alpha 3) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2) (Insulin-stimulated protein kinase 1) (ISPK-1) (MAP kinase-activated protein kinase 1b) (MAPKAPK1B).

KS6A3_MOUSE
NC score	-0.001193 (rank : 23)	θ value	8.99809 (rank : 22)
Query Neighborhood Hits	23	Target Neighborhood Hits	860	Shared Neighborhood Hits	3
SwissProt Accessions	P18654, Q03140, Q8K3J8	Gene names	Rps6ka3, Rps6ka-rs1, Rsk2
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-3 (EC 2.7.11.1) (S6K-alpha 3) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2) (MAP kinase-activated protein kinase 1b) (MAPKAPK1B).