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Network neighborhood for query Sequence : SC5A5_HUMAN

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SC5A5_HUMAN
SwissProt Accessions	Q92911, O43702, Q9NYB6	Gene names	SLC5A5, NIS
Domain Architecture
Description	Sodium/iodide cotransporter (Na(+)/I(-) cotransporter) (Sodium-iodide symporter) (Na(+)/I(-)-symporter).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SC5A5_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	22	Target Neighborhood Hits	22	Shared Neighborhood Hits	22
SwissProt Accessions	Q92911, O43702, Q9NYB6	Gene names	SLC5A5, NIS
Domain Architecture
Description	Sodium/iodide cotransporter (Na(+)/I(-) cotransporter) (Sodium-iodide symporter) (Na(+)/I(-)-symporter).

SC5A5_MOUSE
θ value	0 (rank : 2)	NC score	0.996591 (rank : 2)
Query Neighborhood Hits	22	Target Neighborhood Hits	23	Shared Neighborhood Hits	15
SwissProt Accessions	Q99PN0	Gene names	Slc5a5, Nis
Domain Architecture	No domain graphic available
Description	Sodium/iodide cotransporter (Na(+)/I(-) cotransporter) (Sodium-iodide symporter) (Na(+)/I(-)-symporter).

SC5A6_HUMAN
θ value	3.77839e-115 (rank : 3)	NC score	0.959639 (rank : 3)
Query Neighborhood Hits	22	Target Neighborhood Hits	28	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y289	Gene names	SLC5A6, SMVT
Domain Architecture
Description	Sodium-dependent multivitamin transporter (Na(+)-dependent multivitamin transporter).

SC5A6_MOUSE
θ value	3.42535e-108 (rank : 4)	NC score	0.958202 (rank : 4)
Query Neighborhood Hits	22	Target Neighborhood Hits	16	Shared Neighborhood Hits	14
SwissProt Accessions	Q5U4D8	Gene names	Slc5a6
Domain Architecture	No domain graphic available
Description	Sodium-dependent multivitamin transporter (Na(+)-dependent multivitamin transporter).

SC5A4_MOUSE
θ value	4.15078e-21 (rank : 5)	NC score	0.689307 (rank : 5)
Query Neighborhood Hits	22	Target Neighborhood Hits	32	Shared Neighborhood Hits	14
SwissProt Accessions	Q9ET37	Gene names	Slc5a4a
Domain Architecture
Description	Low affinity sodium-glucose cotransporter (Sodium/glucose cotransporter 3) (Na(+)/glucose cotransporter 3).

SC5A2_HUMAN
θ value	1.2077e-20 (rank : 6)	NC score	0.680608 (rank : 8)
Query Neighborhood Hits	22	Target Neighborhood Hits	20	Shared Neighborhood Hits	14
SwissProt Accessions	P31639	Gene names	SLC5A2, SGLT2
Domain Architecture
Description	Sodium/glucose cotransporter 2 (Na(+)/glucose cotransporter 2) (Low affinity sodium-glucose cotransporter).

SC5A3_HUMAN
θ value	3.51386e-20 (rank : 7)	NC score	0.672591 (rank : 12)
Query Neighborhood Hits	22	Target Neighborhood Hits	35	Shared Neighborhood Hits	14
SwissProt Accessions	P53794, O43489	Gene names	SLC5A3
Domain Architecture
Description	Sodium/myo-inositol cotransporter (Na(+)/myo-inositol cotransporter).

SC5A4_HUMAN
θ value	4.58923e-20 (rank : 8)	NC score	0.687601 (rank : 6)
Query Neighborhood Hits	22	Target Neighborhood Hits	26	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NY91, O15279	Gene names	SLC5A4, SAAT1, SGLT2
Domain Architecture
Description	Low affinity sodium-glucose cotransporter (Sodium/glucose cotransporter 3) (Na(+)/glucose cotransporter 3).

SC5A3_MOUSE
θ value	1.02238e-19 (rank : 9)	NC score	0.680655 (rank : 7)
Query Neighborhood Hits	22	Target Neighborhood Hits	29	Shared Neighborhood Hits	14
SwissProt Accessions	Q9JKZ2	Gene names	Slc5a3
Domain Architecture
Description	Sodium/myo-inositol cotransporter (Na(+)/myo-inositol cotransporter).

SC5A1_HUMAN
θ value	1.33526e-19 (rank : 10)	NC score	0.675581 (rank : 9)
Query Neighborhood Hits	22	Target Neighborhood Hits	20	Shared Neighborhood Hits	15
SwissProt Accessions	P13866	Gene names	SLC5A1, NAGT, SGLT1
Domain Architecture
Description	Sodium/glucose cotransporter 1 (Na(+)/glucose cotransporter 1) (High affinity sodium-glucose cotransporter).

SC5A2_MOUSE
θ value	2.97466e-19 (rank : 11)	NC score	0.674306 (rank : 11)
Query Neighborhood Hits	22	Target Neighborhood Hits	18	Shared Neighborhood Hits	14
SwissProt Accessions	Q923I7	Gene names	Slc5a2, Sglt2
Domain Architecture	No domain graphic available
Description	Sodium/glucose cotransporter 2 (Na(+)/glucose cotransporter 2) (Low affinity sodium-glucose cotransporter).

SC5A1_MOUSE
θ value	1.92812e-18 (rank : 12)	NC score	0.675442 (rank : 10)
Query Neighborhood Hits	22	Target Neighborhood Hits	24	Shared Neighborhood Hits	15
SwissProt Accessions	Q8C3K6	Gene names	Slc5a1
Domain Architecture	No domain graphic available
Description	Sodium/glucose cotransporter 1 (Na(+)/glucose cotransporter 1) (High affinity sodium-glucose cotransporter).

SC5A7_HUMAN
θ value	2.28291e-11 (rank : 13)	NC score	0.539550 (rank : 13)
Query Neighborhood Hits	22	Target Neighborhood Hits	16	Shared Neighborhood Hits	14
SwissProt Accessions	Q9GZV3	Gene names	SLC5A7, CHT1
Domain Architecture	No domain graphic available
Description	High-affinity choline transporter 1 (Solute carrier family 5 member 7) (Hemicholinium-3-sensitive choline transporter) (CHT).

SC5A7_MOUSE
θ value	3.64472e-09 (rank : 14)	NC score	0.505280 (rank : 14)
Query Neighborhood Hits	22	Target Neighborhood Hits	16	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BGY9, Q99PK3, Q9ESW5	Gene names	Slc5a7, Cht1
Domain Architecture	No domain graphic available
Description	High-affinity choline transporter 1 (Solute carrier family 5 member 7) (Hemicholinium-3-sensitive choline transporter) (CHT).

TARA_HUMAN
θ value	0.47712 (rank : 15)	NC score	0.012764 (rank : 17)
Query Neighborhood Hits	22	Target Neighborhood Hits	1626	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

S29A1_MOUSE
θ value	1.38821 (rank : 16)	NC score	0.025729 (rank : 15)
Query Neighborhood Hits	22	Target Neighborhood Hits	16	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JIM1, Q99K84, Q9DBT8, Q9JHF0	Gene names	Slc29a1, Ent1
Domain Architecture
Description	Equilibrative nucleoside transporter 1 (Equilibrative nitrobenzylmercaptopurine riboside-sensitive nucleoside transporter) (Equilibrative NBMPR-sensitive nucleoside transporter) (Nucleoside transporter, es-type) (Solute carrier family 29 member 1).

DGAT2_HUMAN
θ value	4.03905 (rank : 17)	NC score	0.009826 (rank : 19)
Query Neighborhood Hits	22	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	Q96PD7, Q5U810, Q68CL3, Q68DJ0, Q8NDB7, Q96BS0, Q9BYE5	Gene names	DGAT2
Domain Architecture	No domain graphic available
Description	Diacylglycerol O-acyltransferase 2 (EC 2.3.1.20) (Diglyceride acyltransferase 2).

OR6C3_HUMAN
θ value	6.88961 (rank : 18)	NC score	-0.000681 (rank : 22)
Query Neighborhood Hits	22	Target Neighborhood Hits	784	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NZP0	Gene names	OR6C3
Domain Architecture	No domain graphic available
Description	Olfactory receptor 6C3 (HSA8).

S29A1_HUMAN
θ value	6.88961 (rank : 19)	NC score	0.020022 (rank : 16)
Query Neighborhood Hits	22	Target Neighborhood Hits	18	Shared Neighborhood Hits	3
SwissProt Accessions	Q99808, Q9UJY2	Gene names	SLC29A1, ENT1
Domain Architecture
Description	Equilibrative nucleoside transporter 1 (Equilibrative nitrobenzylmercaptopurine riboside-sensitive nucleoside transporter) (Equilibrative NBMPR-sensitive nucleoside transporter) (Nucleoside transporter, es-type) (Solute carrier family 29 member 1).

DPOLQ_HUMAN
θ value	8.99809 (rank : 20)	NC score	0.011055 (rank : 18)
Query Neighborhood Hits	22	Target Neighborhood Hits	67	Shared Neighborhood Hits	2
SwissProt Accessions	O75417, O95160	Gene names	POLQ, POLH
Domain Architecture
Description	DNA polymerase theta (EC 2.7.7.7) (DNA polymerase eta).

GP120_HUMAN
θ value	8.99809 (rank : 21)	NC score	0.005945 (rank : 21)
Query Neighborhood Hits	22	Target Neighborhood Hits	458	Shared Neighborhood Hits	3
SwissProt Accessions	Q5NUL3, Q5VY25, Q5VY26, Q7Z605, Q86SM7	Gene names	GPR120, GPR129, PGR4
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 120 (G-protein coupled receptor PGR4) (G- protein coupled receptor GT01) (G-protein coupled receptor 129).

VACHT_MOUSE
θ value	8.99809 (rank : 22)	NC score	0.007710 (rank : 20)
Query Neighborhood Hits	22	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	O35304	Gene names	Slc18a3, Vacht
Domain Architecture
Description	Vesicular acetylcholine transporter (VAChT) (Solute carrier family 18 member 3).

Hits sorted by NC score

SC5A5_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	22	Target Neighborhood Hits	22	Shared Neighborhood Hits	22
SwissProt Accessions	Q92911, O43702, Q9NYB6	Gene names	SLC5A5, NIS
Domain Architecture
Description	Sodium/iodide cotransporter (Na(+)/I(-) cotransporter) (Sodium-iodide symporter) (Na(+)/I(-)-symporter).

SC5A5_MOUSE
NC score	0.996591 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	22	Target Neighborhood Hits	23	Shared Neighborhood Hits	15
SwissProt Accessions	Q99PN0	Gene names	Slc5a5, Nis
Domain Architecture	No domain graphic available
Description	Sodium/iodide cotransporter (Na(+)/I(-) cotransporter) (Sodium-iodide symporter) (Na(+)/I(-)-symporter).

SC5A6_HUMAN
NC score	0.959639 (rank : 3)	θ value	3.77839e-115 (rank : 3)
Query Neighborhood Hits	22	Target Neighborhood Hits	28	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y289	Gene names	SLC5A6, SMVT
Domain Architecture
Description	Sodium-dependent multivitamin transporter (Na(+)-dependent multivitamin transporter).

SC5A6_MOUSE
NC score	0.958202 (rank : 4)	θ value	3.42535e-108 (rank : 4)
Query Neighborhood Hits	22	Target Neighborhood Hits	16	Shared Neighborhood Hits	14
SwissProt Accessions	Q5U4D8	Gene names	Slc5a6
Domain Architecture	No domain graphic available
Description	Sodium-dependent multivitamin transporter (Na(+)-dependent multivitamin transporter).

SC5A4_MOUSE
NC score	0.689307 (rank : 5)	θ value	4.15078e-21 (rank : 5)
Query Neighborhood Hits	22	Target Neighborhood Hits	32	Shared Neighborhood Hits	14
SwissProt Accessions	Q9ET37	Gene names	Slc5a4a
Domain Architecture
Description	Low affinity sodium-glucose cotransporter (Sodium/glucose cotransporter 3) (Na(+)/glucose cotransporter 3).

SC5A4_HUMAN
NC score	0.687601 (rank : 6)	θ value	4.58923e-20 (rank : 8)
Query Neighborhood Hits	22	Target Neighborhood Hits	26	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NY91, O15279	Gene names	SLC5A4, SAAT1, SGLT2
Domain Architecture
Description	Low affinity sodium-glucose cotransporter (Sodium/glucose cotransporter 3) (Na(+)/glucose cotransporter 3).

SC5A3_MOUSE
NC score	0.680655 (rank : 7)	θ value	1.02238e-19 (rank : 9)
Query Neighborhood Hits	22	Target Neighborhood Hits	29	Shared Neighborhood Hits	14
SwissProt Accessions	Q9JKZ2	Gene names	Slc5a3
Domain Architecture
Description	Sodium/myo-inositol cotransporter (Na(+)/myo-inositol cotransporter).

SC5A2_HUMAN
NC score	0.680608 (rank : 8)	θ value	1.2077e-20 (rank : 6)
Query Neighborhood Hits	22	Target Neighborhood Hits	20	Shared Neighborhood Hits	14
SwissProt Accessions	P31639	Gene names	SLC5A2, SGLT2
Domain Architecture
Description	Sodium/glucose cotransporter 2 (Na(+)/glucose cotransporter 2) (Low affinity sodium-glucose cotransporter).

SC5A1_HUMAN
NC score	0.675581 (rank : 9)	θ value	1.33526e-19 (rank : 10)
Query Neighborhood Hits	22	Target Neighborhood Hits	20	Shared Neighborhood Hits	15
SwissProt Accessions	P13866	Gene names	SLC5A1, NAGT, SGLT1
Domain Architecture
Description	Sodium/glucose cotransporter 1 (Na(+)/glucose cotransporter 1) (High affinity sodium-glucose cotransporter).

SC5A1_MOUSE
NC score	0.675442 (rank : 10)	θ value	1.92812e-18 (rank : 12)
Query Neighborhood Hits	22	Target Neighborhood Hits	24	Shared Neighborhood Hits	15
SwissProt Accessions	Q8C3K6	Gene names	Slc5a1
Domain Architecture	No domain graphic available
Description	Sodium/glucose cotransporter 1 (Na(+)/glucose cotransporter 1) (High affinity sodium-glucose cotransporter).

SC5A2_MOUSE
NC score	0.674306 (rank : 11)	θ value	2.97466e-19 (rank : 11)
Query Neighborhood Hits	22	Target Neighborhood Hits	18	Shared Neighborhood Hits	14
SwissProt Accessions	Q923I7	Gene names	Slc5a2, Sglt2
Domain Architecture	No domain graphic available
Description	Sodium/glucose cotransporter 2 (Na(+)/glucose cotransporter 2) (Low affinity sodium-glucose cotransporter).

SC5A3_HUMAN
NC score	0.672591 (rank : 12)	θ value	3.51386e-20 (rank : 7)
Query Neighborhood Hits	22	Target Neighborhood Hits	35	Shared Neighborhood Hits	14
SwissProt Accessions	P53794, O43489	Gene names	SLC5A3
Domain Architecture
Description	Sodium/myo-inositol cotransporter (Na(+)/myo-inositol cotransporter).

SC5A7_HUMAN
NC score	0.539550 (rank : 13)	θ value	2.28291e-11 (rank : 13)
Query Neighborhood Hits	22	Target Neighborhood Hits	16	Shared Neighborhood Hits	14
SwissProt Accessions	Q9GZV3	Gene names	SLC5A7, CHT1
Domain Architecture	No domain graphic available
Description	High-affinity choline transporter 1 (Solute carrier family 5 member 7) (Hemicholinium-3-sensitive choline transporter) (CHT).

SC5A7_MOUSE
NC score	0.505280 (rank : 14)	θ value	3.64472e-09 (rank : 14)
Query Neighborhood Hits	22	Target Neighborhood Hits	16	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BGY9, Q99PK3, Q9ESW5	Gene names	Slc5a7, Cht1
Domain Architecture	No domain graphic available
Description	High-affinity choline transporter 1 (Solute carrier family 5 member 7) (Hemicholinium-3-sensitive choline transporter) (CHT).

S29A1_MOUSE
NC score	0.025729 (rank : 15)	θ value	1.38821 (rank : 16)
Query Neighborhood Hits	22	Target Neighborhood Hits	16	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JIM1, Q99K84, Q9DBT8, Q9JHF0	Gene names	Slc29a1, Ent1
Domain Architecture
Description	Equilibrative nucleoside transporter 1 (Equilibrative nitrobenzylmercaptopurine riboside-sensitive nucleoside transporter) (Equilibrative NBMPR-sensitive nucleoside transporter) (Nucleoside transporter, es-type) (Solute carrier family 29 member 1).

S29A1_HUMAN
NC score	0.020022 (rank : 16)	θ value	6.88961 (rank : 19)
Query Neighborhood Hits	22	Target Neighborhood Hits	18	Shared Neighborhood Hits	3
SwissProt Accessions	Q99808, Q9UJY2	Gene names	SLC29A1, ENT1
Domain Architecture
Description	Equilibrative nucleoside transporter 1 (Equilibrative nitrobenzylmercaptopurine riboside-sensitive nucleoside transporter) (Equilibrative NBMPR-sensitive nucleoside transporter) (Nucleoside transporter, es-type) (Solute carrier family 29 member 1).

TARA_HUMAN
NC score	0.012764 (rank : 17)	θ value	0.47712 (rank : 15)
Query Neighborhood Hits	22	Target Neighborhood Hits	1626	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

DPOLQ_HUMAN
NC score	0.011055 (rank : 18)	θ value	8.99809 (rank : 20)
Query Neighborhood Hits	22	Target Neighborhood Hits	67	Shared Neighborhood Hits	2
SwissProt Accessions	O75417, O95160	Gene names	POLQ, POLH
Domain Architecture
Description	DNA polymerase theta (EC 2.7.7.7) (DNA polymerase eta).

DGAT2_HUMAN
NC score	0.009826 (rank : 19)	θ value	4.03905 (rank : 17)
Query Neighborhood Hits	22	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	Q96PD7, Q5U810, Q68CL3, Q68DJ0, Q8NDB7, Q96BS0, Q9BYE5	Gene names	DGAT2
Domain Architecture	No domain graphic available
Description	Diacylglycerol O-acyltransferase 2 (EC 2.3.1.20) (Diglyceride acyltransferase 2).

VACHT_MOUSE
NC score	0.007710 (rank : 20)	θ value	8.99809 (rank : 22)
Query Neighborhood Hits	22	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	O35304	Gene names	Slc18a3, Vacht
Domain Architecture
Description	Vesicular acetylcholine transporter (VAChT) (Solute carrier family 18 member 3).

GP120_HUMAN
NC score	0.005945 (rank : 21)	θ value	8.99809 (rank : 21)
Query Neighborhood Hits	22	Target Neighborhood Hits	458	Shared Neighborhood Hits	3
SwissProt Accessions	Q5NUL3, Q5VY25, Q5VY26, Q7Z605, Q86SM7	Gene names	GPR120, GPR129, PGR4
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 120 (G-protein coupled receptor PGR4) (G- protein coupled receptor GT01) (G-protein coupled receptor 129).

OR6C3_HUMAN
NC score	-0.000681 (rank : 22)	θ value	6.88961 (rank : 18)
Query Neighborhood Hits	22	Target Neighborhood Hits	784	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NZP0	Gene names	OR6C3
Domain Architecture	No domain graphic available
Description	Olfactory receptor 6C3 (HSA8).