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Network neighborhood for query Sequence : SC5A1_HUMAN

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SC5A1_HUMAN
SwissProt Accessions	P13866	Gene names	SLC5A1, NAGT, SGLT1
Domain Architecture
Description	Sodium/glucose cotransporter 1 (Na(+)/glucose cotransporter 1) (High affinity sodium-glucose cotransporter).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SC5A1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	20	Target Neighborhood Hits	20	Shared Neighborhood Hits	20
SwissProt Accessions	P13866	Gene names	SLC5A1, NAGT, SGLT1
Domain Architecture
Description	Sodium/glucose cotransporter 1 (Na(+)/glucose cotransporter 1) (High affinity sodium-glucose cotransporter).

SC5A1_MOUSE
θ value	0 (rank : 2)	NC score	0.998996 (rank : 2)
Query Neighborhood Hits	20	Target Neighborhood Hits	24	Shared Neighborhood Hits	17
SwissProt Accessions	Q8C3K6	Gene names	Slc5a1
Domain Architecture	No domain graphic available
Description	Sodium/glucose cotransporter 1 (Na(+)/glucose cotransporter 1) (High affinity sodium-glucose cotransporter).

SC5A2_HUMAN
θ value	0 (rank : 3)	NC score	0.994988 (rank : 5)
Query Neighborhood Hits	20	Target Neighborhood Hits	20	Shared Neighborhood Hits	16
SwissProt Accessions	P31639	Gene names	SLC5A2, SGLT2
Domain Architecture
Description	Sodium/glucose cotransporter 2 (Na(+)/glucose cotransporter 2) (Low affinity sodium-glucose cotransporter).

SC5A2_MOUSE
θ value	0 (rank : 4)	NC score	0.994930 (rank : 6)
Query Neighborhood Hits	20	Target Neighborhood Hits	18	Shared Neighborhood Hits	15
SwissProt Accessions	Q923I7	Gene names	Slc5a2, Sglt2
Domain Architecture	No domain graphic available
Description	Sodium/glucose cotransporter 2 (Na(+)/glucose cotransporter 2) (Low affinity sodium-glucose cotransporter).

SC5A4_HUMAN
θ value	0 (rank : 5)	NC score	0.997445 (rank : 3)
Query Neighborhood Hits	20	Target Neighborhood Hits	26	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NY91, O15279	Gene names	SLC5A4, SAAT1, SGLT2
Domain Architecture
Description	Low affinity sodium-glucose cotransporter (Sodium/glucose cotransporter 3) (Na(+)/glucose cotransporter 3).

SC5A4_MOUSE
θ value	0 (rank : 6)	NC score	0.996619 (rank : 4)
Query Neighborhood Hits	20	Target Neighborhood Hits	32	Shared Neighborhood Hits	16
SwissProt Accessions	Q9ET37	Gene names	Slc5a4a
Domain Architecture
Description	Low affinity sodium-glucose cotransporter (Sodium/glucose cotransporter 3) (Na(+)/glucose cotransporter 3).

SC5A3_MOUSE
θ value	1.845e-170 (rank : 7)	NC score	0.982394 (rank : 8)
Query Neighborhood Hits	20	Target Neighborhood Hits	29	Shared Neighborhood Hits	17
SwissProt Accessions	Q9JKZ2	Gene names	Slc5a3
Domain Architecture
Description	Sodium/myo-inositol cotransporter (Na(+)/myo-inositol cotransporter).

SC5A3_HUMAN
θ value	3.14709e-170 (rank : 8)	NC score	0.982933 (rank : 7)
Query Neighborhood Hits	20	Target Neighborhood Hits	35	Shared Neighborhood Hits	17
SwissProt Accessions	P53794, O43489	Gene names	SLC5A3
Domain Architecture
Description	Sodium/myo-inositol cotransporter (Na(+)/myo-inositol cotransporter).

SC5A6_HUMAN
θ value	3.75424e-22 (rank : 9)	NC score	0.669095 (rank : 10)
Query Neighborhood Hits	20	Target Neighborhood Hits	28	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y289	Gene names	SLC5A6, SMVT
Domain Architecture
Description	Sodium-dependent multivitamin transporter (Na(+)-dependent multivitamin transporter).

SC5A5_HUMAN
θ value	1.33526e-19 (rank : 10)	NC score	0.675581 (rank : 9)
Query Neighborhood Hits	20	Target Neighborhood Hits	22	Shared Neighborhood Hits	15
SwissProt Accessions	Q92911, O43702, Q9NYB6	Gene names	SLC5A5, NIS
Domain Architecture
Description	Sodium/iodide cotransporter (Na(+)/I(-) cotransporter) (Sodium-iodide symporter) (Na(+)/I(-)-symporter).

SC5A5_MOUSE
θ value	7.32683e-18 (rank : 11)	NC score	0.666237 (rank : 11)
Query Neighborhood Hits	20	Target Neighborhood Hits	23	Shared Neighborhood Hits	14
SwissProt Accessions	Q99PN0	Gene names	Slc5a5, Nis
Domain Architecture	No domain graphic available
Description	Sodium/iodide cotransporter (Na(+)/I(-) cotransporter) (Sodium-iodide symporter) (Na(+)/I(-)-symporter).

SC5A6_MOUSE
θ value	9.26847e-13 (rank : 12)	NC score	0.625764 (rank : 12)
Query Neighborhood Hits	20	Target Neighborhood Hits	16	Shared Neighborhood Hits	14
SwissProt Accessions	Q5U4D8	Gene names	Slc5a6
Domain Architecture	No domain graphic available
Description	Sodium-dependent multivitamin transporter (Na(+)-dependent multivitamin transporter).

SC5A7_HUMAN
θ value	2.79066e-09 (rank : 13)	NC score	0.551265 (rank : 13)
Query Neighborhood Hits	20	Target Neighborhood Hits	16	Shared Neighborhood Hits	14
SwissProt Accessions	Q9GZV3	Gene names	SLC5A7, CHT1
Domain Architecture	No domain graphic available
Description	High-affinity choline transporter 1 (Solute carrier family 5 member 7) (Hemicholinium-3-sensitive choline transporter) (CHT).

SC5A7_MOUSE
θ value	2.61198e-07 (rank : 14)	NC score	0.517203 (rank : 14)
Query Neighborhood Hits	20	Target Neighborhood Hits	16	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BGY9, Q99PK3, Q9ESW5	Gene names	Slc5a7, Cht1
Domain Architecture	No domain graphic available
Description	High-affinity choline transporter 1 (Solute carrier family 5 member 7) (Hemicholinium-3-sensitive choline transporter) (CHT).

RXFP2_MOUSE
θ value	0.279714 (rank : 15)	NC score	0.008298 (rank : 18)
Query Neighborhood Hits	20	Target Neighborhood Hits	760	Shared Neighborhood Hits	3
SwissProt Accessions	Q91ZZ5	Gene names	Rxfp2, Gpr106, Great, Lgr8
Domain Architecture
Description	Relaxin receptor 2 (Relaxin family peptide receptor 2) (Leucine-rich repeat-containing G-protein coupled receptor 8) (G-protein coupled receptor affecting testicular descent) (G-protein coupled receptor 106).

S6A11_MOUSE
θ value	4.03905 (rank : 16)	NC score	0.016245 (rank : 17)
Query Neighborhood Hits	20	Target Neighborhood Hits	48	Shared Neighborhood Hits	8
SwissProt Accessions	P31650	Gene names	Slc6a11, Gabt4, Gat-4, Gat4
Domain Architecture	No domain graphic available
Description	Sodium- and chloride-dependent GABA transporter 4 (GAT4).

RXFP2_HUMAN
θ value	5.27518 (rank : 17)	NC score	0.007254 (rank : 19)
Query Neighborhood Hits	20	Target Neighborhood Hits	736	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WXD0	Gene names	RXFP2, GPR106, GREAT, LGR8
Domain Architecture
Description	Relaxin receptor 2 (Relaxin family peptide receptor 2) (Leucine-rich repeat-containing G-protein coupled receptor 8) (G-protein coupled receptor affecting testicular descent) (G-protein coupled receptor 106).

S6A11_HUMAN
θ value	5.27518 (rank : 18)	NC score	0.018347 (rank : 16)
Query Neighborhood Hits	20	Target Neighborhood Hits	48	Shared Neighborhood Hits	9
SwissProt Accessions	P48066	Gene names	SLC6A11, GABT3, GAT3
Domain Architecture
Description	Sodium- and chloride-dependent GABA transporter 3.

OR6C3_HUMAN
θ value	8.99809 (rank : 19)	NC score	-0.000470 (rank : 20)
Query Neighborhood Hits	20	Target Neighborhood Hits	784	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NZP0	Gene names	OR6C3
Domain Architecture	No domain graphic available
Description	Olfactory receptor 6C3 (HSA8).

TSN8_HUMAN
θ value	8.99809 (rank : 20)	NC score	0.027304 (rank : 15)
Query Neighborhood Hits	20	Target Neighborhood Hits	53	Shared Neighborhood Hits	5
SwissProt Accessions	P19075, Q9BS78	Gene names	TSPAN8, TM4SF3
Domain Architecture
Description	Tetraspanin-8 (Tspan-8) (Transmembrane 4 superfamily member 3) (Tumor- associated antigen CO-029).

Hits sorted by NC score

SC5A1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	20	Target Neighborhood Hits	20	Shared Neighborhood Hits	20
SwissProt Accessions	P13866	Gene names	SLC5A1, NAGT, SGLT1
Domain Architecture
Description	Sodium/glucose cotransporter 1 (Na(+)/glucose cotransporter 1) (High affinity sodium-glucose cotransporter).

SC5A1_MOUSE
NC score	0.998996 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	20	Target Neighborhood Hits	24	Shared Neighborhood Hits	17
SwissProt Accessions	Q8C3K6	Gene names	Slc5a1
Domain Architecture	No domain graphic available
Description	Sodium/glucose cotransporter 1 (Na(+)/glucose cotransporter 1) (High affinity sodium-glucose cotransporter).

SC5A4_HUMAN
NC score	0.997445 (rank : 3)	θ value	0 (rank : 5)
Query Neighborhood Hits	20	Target Neighborhood Hits	26	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NY91, O15279	Gene names	SLC5A4, SAAT1, SGLT2
Domain Architecture
Description	Low affinity sodium-glucose cotransporter (Sodium/glucose cotransporter 3) (Na(+)/glucose cotransporter 3).

SC5A4_MOUSE
NC score	0.996619 (rank : 4)	θ value	0 (rank : 6)
Query Neighborhood Hits	20	Target Neighborhood Hits	32	Shared Neighborhood Hits	16
SwissProt Accessions	Q9ET37	Gene names	Slc5a4a
Domain Architecture
Description	Low affinity sodium-glucose cotransporter (Sodium/glucose cotransporter 3) (Na(+)/glucose cotransporter 3).

SC5A2_HUMAN
NC score	0.994988 (rank : 5)	θ value	0 (rank : 3)
Query Neighborhood Hits	20	Target Neighborhood Hits	20	Shared Neighborhood Hits	16
SwissProt Accessions	P31639	Gene names	SLC5A2, SGLT2
Domain Architecture
Description	Sodium/glucose cotransporter 2 (Na(+)/glucose cotransporter 2) (Low affinity sodium-glucose cotransporter).

SC5A2_MOUSE
NC score	0.994930 (rank : 6)	θ value	0 (rank : 4)
Query Neighborhood Hits	20	Target Neighborhood Hits	18	Shared Neighborhood Hits	15
SwissProt Accessions	Q923I7	Gene names	Slc5a2, Sglt2
Domain Architecture	No domain graphic available
Description	Sodium/glucose cotransporter 2 (Na(+)/glucose cotransporter 2) (Low affinity sodium-glucose cotransporter).

SC5A3_HUMAN
NC score	0.982933 (rank : 7)	θ value	3.14709e-170 (rank : 8)
Query Neighborhood Hits	20	Target Neighborhood Hits	35	Shared Neighborhood Hits	17
SwissProt Accessions	P53794, O43489	Gene names	SLC5A3
Domain Architecture
Description	Sodium/myo-inositol cotransporter (Na(+)/myo-inositol cotransporter).

SC5A3_MOUSE
NC score	0.982394 (rank : 8)	θ value	1.845e-170 (rank : 7)
Query Neighborhood Hits	20	Target Neighborhood Hits	29	Shared Neighborhood Hits	17
SwissProt Accessions	Q9JKZ2	Gene names	Slc5a3
Domain Architecture
Description	Sodium/myo-inositol cotransporter (Na(+)/myo-inositol cotransporter).

SC5A5_HUMAN
NC score	0.675581 (rank : 9)	θ value	1.33526e-19 (rank : 10)
Query Neighborhood Hits	20	Target Neighborhood Hits	22	Shared Neighborhood Hits	15
SwissProt Accessions	Q92911, O43702, Q9NYB6	Gene names	SLC5A5, NIS
Domain Architecture
Description	Sodium/iodide cotransporter (Na(+)/I(-) cotransporter) (Sodium-iodide symporter) (Na(+)/I(-)-symporter).

SC5A6_HUMAN
NC score	0.669095 (rank : 10)	θ value	3.75424e-22 (rank : 9)
Query Neighborhood Hits	20	Target Neighborhood Hits	28	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y289	Gene names	SLC5A6, SMVT
Domain Architecture
Description	Sodium-dependent multivitamin transporter (Na(+)-dependent multivitamin transporter).

SC5A5_MOUSE
NC score	0.666237 (rank : 11)	θ value	7.32683e-18 (rank : 11)
Query Neighborhood Hits	20	Target Neighborhood Hits	23	Shared Neighborhood Hits	14
SwissProt Accessions	Q99PN0	Gene names	Slc5a5, Nis
Domain Architecture	No domain graphic available
Description	Sodium/iodide cotransporter (Na(+)/I(-) cotransporter) (Sodium-iodide symporter) (Na(+)/I(-)-symporter).

SC5A6_MOUSE
NC score	0.625764 (rank : 12)	θ value	9.26847e-13 (rank : 12)
Query Neighborhood Hits	20	Target Neighborhood Hits	16	Shared Neighborhood Hits	14
SwissProt Accessions	Q5U4D8	Gene names	Slc5a6
Domain Architecture	No domain graphic available
Description	Sodium-dependent multivitamin transporter (Na(+)-dependent multivitamin transporter).

SC5A7_HUMAN
NC score	0.551265 (rank : 13)	θ value	2.79066e-09 (rank : 13)
Query Neighborhood Hits	20	Target Neighborhood Hits	16	Shared Neighborhood Hits	14
SwissProt Accessions	Q9GZV3	Gene names	SLC5A7, CHT1
Domain Architecture	No domain graphic available
Description	High-affinity choline transporter 1 (Solute carrier family 5 member 7) (Hemicholinium-3-sensitive choline transporter) (CHT).

SC5A7_MOUSE
NC score	0.517203 (rank : 14)	θ value	2.61198e-07 (rank : 14)
Query Neighborhood Hits	20	Target Neighborhood Hits	16	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BGY9, Q99PK3, Q9ESW5	Gene names	Slc5a7, Cht1
Domain Architecture	No domain graphic available
Description	High-affinity choline transporter 1 (Solute carrier family 5 member 7) (Hemicholinium-3-sensitive choline transporter) (CHT).

TSN8_HUMAN
NC score	0.027304 (rank : 15)	θ value	8.99809 (rank : 20)
Query Neighborhood Hits	20	Target Neighborhood Hits	53	Shared Neighborhood Hits	5
SwissProt Accessions	P19075, Q9BS78	Gene names	TSPAN8, TM4SF3
Domain Architecture
Description	Tetraspanin-8 (Tspan-8) (Transmembrane 4 superfamily member 3) (Tumor- associated antigen CO-029).

S6A11_HUMAN
NC score	0.018347 (rank : 16)	θ value	5.27518 (rank : 18)
Query Neighborhood Hits	20	Target Neighborhood Hits	48	Shared Neighborhood Hits	9
SwissProt Accessions	P48066	Gene names	SLC6A11, GABT3, GAT3
Domain Architecture
Description	Sodium- and chloride-dependent GABA transporter 3.

S6A11_MOUSE
NC score	0.016245 (rank : 17)	θ value	4.03905 (rank : 16)
Query Neighborhood Hits	20	Target Neighborhood Hits	48	Shared Neighborhood Hits	8
SwissProt Accessions	P31650	Gene names	Slc6a11, Gabt4, Gat-4, Gat4
Domain Architecture	No domain graphic available
Description	Sodium- and chloride-dependent GABA transporter 4 (GAT4).

RXFP2_MOUSE
NC score	0.008298 (rank : 18)	θ value	0.279714 (rank : 15)
Query Neighborhood Hits	20	Target Neighborhood Hits	760	Shared Neighborhood Hits	3
SwissProt Accessions	Q91ZZ5	Gene names	Rxfp2, Gpr106, Great, Lgr8
Domain Architecture
Description	Relaxin receptor 2 (Relaxin family peptide receptor 2) (Leucine-rich repeat-containing G-protein coupled receptor 8) (G-protein coupled receptor affecting testicular descent) (G-protein coupled receptor 106).

RXFP2_HUMAN
NC score	0.007254 (rank : 19)	θ value	5.27518 (rank : 17)
Query Neighborhood Hits	20	Target Neighborhood Hits	736	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WXD0	Gene names	RXFP2, GPR106, GREAT, LGR8
Domain Architecture
Description	Relaxin receptor 2 (Relaxin family peptide receptor 2) (Leucine-rich repeat-containing G-protein coupled receptor 8) (G-protein coupled receptor affecting testicular descent) (G-protein coupled receptor 106).

OR6C3_HUMAN
NC score	-0.000470 (rank : 20)	θ value	8.99809 (rank : 19)
Query Neighborhood Hits	20	Target Neighborhood Hits	784	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NZP0	Gene names	OR6C3
Domain Architecture	No domain graphic available
Description	Olfactory receptor 6C3 (HSA8).