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Network neighborhood for query Sequence : RIOK3_HUMAN

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RIOK3_HUMAN
SwissProt Accessions	O14730, Q8IXN9	Gene names	RIOK3, SUDD
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase RIO3 (EC 2.7.11.1) (RIO kinase 3) (sudD homolog).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

RIOK3_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	13	Target Neighborhood Hits	13	Shared Neighborhood Hits	13
SwissProt Accessions	O14730, Q8IXN9	Gene names	RIOK3, SUDD
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase RIO3 (EC 2.7.11.1) (RIO kinase 3) (sudD homolog).

RIOK3_MOUSE
θ value	0 (rank : 2)	NC score	0.998507 (rank : 2)
Query Neighborhood Hits	13	Target Neighborhood Hits	14	Shared Neighborhood Hits	9
SwissProt Accessions	Q9DBU3, Q8CIC1	Gene names	Riok3
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase RIO3 (EC 2.7.11.1) (RIO kinase 3).

RIOK1_HUMAN
θ value	1.96316e-71 (rank : 3)	NC score	0.883734 (rank : 3)
Query Neighborhood Hits	13	Target Neighborhood Hits	86	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BRS2, Q8NDC8, Q96NV9	Gene names	RIOK1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase RIO1 (EC 2.7.11.1) (RIO kinase 1).

RIOK2_HUMAN
θ value	2.21117e-06 (rank : 4)	NC score	0.343546 (rank : 4)
Query Neighborhood Hits	13	Target Neighborhood Hits	125	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BVS4, Q9NUT0	Gene names	RIOK2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase RIO2 (EC 2.7.11.1) (RIO kinase 2).

RIOK2_MOUSE
θ value	2.44474e-05 (rank : 5)	NC score	0.337475 (rank : 5)
Query Neighborhood Hits	13	Target Neighborhood Hits	82	Shared Neighborhood Hits	6
SwissProt Accessions	Q9CQS5, Q91XF3	Gene names	Riok2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase RIO2 (EC 2.7.11.1) (RIO kinase 2).

XPP1_HUMAN
θ value	0.0431538 (rank : 6)	NC score	0.094183 (rank : 6)
Query Neighborhood Hits	13	Target Neighborhood Hits	12	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NQW7, O15250, Q53EX6, Q8N3Q0, Q96D23	Gene names	XPNPEP1, XPNPEPL
Domain Architecture	No domain graphic available
Description	Xaa-Pro aminopeptidase 1 (EC 3.4.11.9) (X-Pro aminopeptidase 1) (X- prolyl aminopeptidase 1, soluble) (Cytosolic aminopeptidase P) (Soluble aminopeptidase P) (sAmp) (Aminoacylproline aminopeptidase).

PRPK_MOUSE
θ value	1.06291 (rank : 7)	NC score	0.041458 (rank : 8)
Query Neighborhood Hits	13	Target Neighborhood Hits	139	Shared Neighborhood Hits	3
SwissProt Accessions	Q99PW4, Q91W37, Q9CZ32	Gene names	Tp53rk, Prpk, Trp53rk
Domain Architecture
Description	TP53-regulating kinase (EC 2.7.11.1) (p53-related protein kinase) (Nori-2).

MRC1_MOUSE
θ value	2.36792 (rank : 8)	NC score	0.018167 (rank : 11)
Query Neighborhood Hits	13	Target Neighborhood Hits	156	Shared Neighborhood Hits	3
SwissProt Accessions	Q61830, Q8C502	Gene names	Mrc1
Domain Architecture	No domain graphic available
Description	Macrophage mannose receptor 1 precursor (MMR) (CD206 antigen).

ANKZ1_HUMAN
θ value	4.03905 (rank : 9)	NC score	0.020708 (rank : 10)
Query Neighborhood Hits	13	Target Neighborhood Hits	236	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H8Y5, Q9NVZ4	Gene names	ANKZF1, ZNF744
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and zinc finger domain-containing protein 1 (Zinc finger protein 744).

FBXL5_HUMAN
θ value	4.03905 (rank : 10)	NC score	0.030159 (rank : 9)
Query Neighborhood Hits	13	Target Neighborhood Hits	111	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UKA1, Q8NHP3, Q9NXN2, Q9P0I0, Q9P0X5, Q9UJT7, Q9UKC8	Gene names	FBXL5, FBL4, FBL5, FLR1
Domain Architecture
Description	F-box/LRR-repeat protein 5 (F-box and leucine-rich repeat protein 5) (F-box protein FBL4/FBL5) (p45SKP2-like protein).

XPP1_MOUSE
θ value	4.03905 (rank : 11)	NC score	0.052227 (rank : 7)
Query Neighborhood Hits	13	Target Neighborhood Hits	11	Shared Neighborhood Hits	3
SwissProt Accessions	Q6P1B1, Q91Y37	Gene names	Xpnpep1
Domain Architecture	No domain graphic available
Description	Xaa-Pro aminopeptidase 1 (EC 3.4.11.9) (X-Pro aminopeptidase 1) (X- prolyl aminopeptidase 1, soluble) (Cytosolic aminopeptidase P) (Soluble aminopeptidase P) (sAmp) (Aminoacylproline aminopeptidase).

DYH9_HUMAN
θ value	5.27518 (rank : 12)	NC score	0.011677 (rank : 12)
Query Neighborhood Hits	13	Target Neighborhood Hits	291	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NYC9, O95494, Q9NQ28	Gene names	DNAH9, DNAH17L, DNAL1
Domain Architecture
Description	Ciliary dynein heavy chain 9 (Axonemal beta dynein heavy chain 9).

ANR26_MOUSE
θ value	6.88961 (rank : 13)	NC score	0.003764 (rank : 13)
Query Neighborhood Hits	13	Target Neighborhood Hits	1554	Shared Neighborhood Hits	4
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

Hits sorted by NC score

RIOK3_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	13	Target Neighborhood Hits	13	Shared Neighborhood Hits	13
SwissProt Accessions	O14730, Q8IXN9	Gene names	RIOK3, SUDD
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase RIO3 (EC 2.7.11.1) (RIO kinase 3) (sudD homolog).

RIOK3_MOUSE
NC score	0.998507 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	13	Target Neighborhood Hits	14	Shared Neighborhood Hits	9
SwissProt Accessions	Q9DBU3, Q8CIC1	Gene names	Riok3
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase RIO3 (EC 2.7.11.1) (RIO kinase 3).

RIOK1_HUMAN
NC score	0.883734 (rank : 3)	θ value	1.96316e-71 (rank : 3)
Query Neighborhood Hits	13	Target Neighborhood Hits	86	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BRS2, Q8NDC8, Q96NV9	Gene names	RIOK1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase RIO1 (EC 2.7.11.1) (RIO kinase 1).

RIOK2_HUMAN
NC score	0.343546 (rank : 4)	θ value	2.21117e-06 (rank : 4)
Query Neighborhood Hits	13	Target Neighborhood Hits	125	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BVS4, Q9NUT0	Gene names	RIOK2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase RIO2 (EC 2.7.11.1) (RIO kinase 2).

RIOK2_MOUSE
NC score	0.337475 (rank : 5)	θ value	2.44474e-05 (rank : 5)
Query Neighborhood Hits	13	Target Neighborhood Hits	82	Shared Neighborhood Hits	6
SwissProt Accessions	Q9CQS5, Q91XF3	Gene names	Riok2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase RIO2 (EC 2.7.11.1) (RIO kinase 2).

XPP1_HUMAN
NC score	0.094183 (rank : 6)	θ value	0.0431538 (rank : 6)
Query Neighborhood Hits	13	Target Neighborhood Hits	12	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NQW7, O15250, Q53EX6, Q8N3Q0, Q96D23	Gene names	XPNPEP1, XPNPEPL
Domain Architecture	No domain graphic available
Description	Xaa-Pro aminopeptidase 1 (EC 3.4.11.9) (X-Pro aminopeptidase 1) (X- prolyl aminopeptidase 1, soluble) (Cytosolic aminopeptidase P) (Soluble aminopeptidase P) (sAmp) (Aminoacylproline aminopeptidase).

XPP1_MOUSE
NC score	0.052227 (rank : 7)	θ value	4.03905 (rank : 11)
Query Neighborhood Hits	13	Target Neighborhood Hits	11	Shared Neighborhood Hits	3
SwissProt Accessions	Q6P1B1, Q91Y37	Gene names	Xpnpep1
Domain Architecture	No domain graphic available
Description	Xaa-Pro aminopeptidase 1 (EC 3.4.11.9) (X-Pro aminopeptidase 1) (X- prolyl aminopeptidase 1, soluble) (Cytosolic aminopeptidase P) (Soluble aminopeptidase P) (sAmp) (Aminoacylproline aminopeptidase).

PRPK_MOUSE
NC score	0.041458 (rank : 8)	θ value	1.06291 (rank : 7)
Query Neighborhood Hits	13	Target Neighborhood Hits	139	Shared Neighborhood Hits	3
SwissProt Accessions	Q99PW4, Q91W37, Q9CZ32	Gene names	Tp53rk, Prpk, Trp53rk
Domain Architecture
Description	TP53-regulating kinase (EC 2.7.11.1) (p53-related protein kinase) (Nori-2).

FBXL5_HUMAN
NC score	0.030159 (rank : 9)	θ value	4.03905 (rank : 10)
Query Neighborhood Hits	13	Target Neighborhood Hits	111	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UKA1, Q8NHP3, Q9NXN2, Q9P0I0, Q9P0X5, Q9UJT7, Q9UKC8	Gene names	FBXL5, FBL4, FBL5, FLR1
Domain Architecture
Description	F-box/LRR-repeat protein 5 (F-box and leucine-rich repeat protein 5) (F-box protein FBL4/FBL5) (p45SKP2-like protein).

ANKZ1_HUMAN
NC score	0.020708 (rank : 10)	θ value	4.03905 (rank : 9)
Query Neighborhood Hits	13	Target Neighborhood Hits	236	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H8Y5, Q9NVZ4	Gene names	ANKZF1, ZNF744
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and zinc finger domain-containing protein 1 (Zinc finger protein 744).

MRC1_MOUSE
NC score	0.018167 (rank : 11)	θ value	2.36792 (rank : 8)
Query Neighborhood Hits	13	Target Neighborhood Hits	156	Shared Neighborhood Hits	3
SwissProt Accessions	Q61830, Q8C502	Gene names	Mrc1
Domain Architecture	No domain graphic available
Description	Macrophage mannose receptor 1 precursor (MMR) (CD206 antigen).

DYH9_HUMAN
NC score	0.011677 (rank : 12)	θ value	5.27518 (rank : 12)
Query Neighborhood Hits	13	Target Neighborhood Hits	291	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NYC9, O95494, Q9NQ28	Gene names	DNAH9, DNAH17L, DNAL1
Domain Architecture
Description	Ciliary dynein heavy chain 9 (Axonemal beta dynein heavy chain 9).

ANR26_MOUSE
NC score	0.003764 (rank : 13)	θ value	6.88961 (rank : 13)
Query Neighborhood Hits	13	Target Neighborhood Hits	1554	Shared Neighborhood Hits	4
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.