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Network neighborhood for query Sequence : PUR8_MOUSE

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PUR8_MOUSE
SwissProt Accessions	P54822	Gene names	Adsl, Adl
Domain Architecture
Description	Adenylosuccinate lyase (EC 4.3.2.2) (Adenylosuccinase) (ASL) (ASASE).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PUR8_HUMAN
θ value	0 (rank : 1)	NC score	0.998076 (rank : 2)
Query Neighborhood Hits	7	Target Neighborhood Hits	9	Shared Neighborhood Hits	4
SwissProt Accessions	P30566, O75495, Q5TI34	Gene names	ADSL, AMPS
Domain Architecture
Description	Adenylosuccinate lyase (EC 4.3.2.2) (Adenylosuccinase) (ASL) (ASASE).

PUR8_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	7	Target Neighborhood Hits	7	Shared Neighborhood Hits	7
SwissProt Accessions	P54822	Gene names	Adsl, Adl
Domain Architecture
Description	Adenylosuccinate lyase (EC 4.3.2.2) (Adenylosuccinase) (ASL) (ASASE).

FUMH_HUMAN
θ value	0.000121331 (rank : 3)	NC score	0.261225 (rank : 3)
Query Neighborhood Hits	7	Target Neighborhood Hits	7	Shared Neighborhood Hits	4
SwissProt Accessions	P07954	Gene names	FH
Domain Architecture
Description	Fumarate hydratase, mitochondrial precursor (EC 4.2.1.2) (Fumarase).

FUMH_MOUSE
θ value	0.000158464 (rank : 4)	NC score	0.260822 (rank : 4)
Query Neighborhood Hits	7	Target Neighborhood Hits	10	Shared Neighborhood Hits	4
SwissProt Accessions	P97807, Q99JL0, Q9DCX0	Gene names	Fh, Fh1
Domain Architecture
Description	Fumarate hydratase, mitochondrial precursor (EC 4.2.1.2) (Fumarase) (EF-3).

IRK2_HUMAN
θ value	6.88961 (rank : 5)	NC score	0.009499 (rank : 6)
Query Neighborhood Hits	7	Target Neighborhood Hits	47	Shared Neighborhood Hits	3
SwissProt Accessions	P63252, O15110, P48049	Gene names	KCNJ2, HIRK1
Domain Architecture	No domain graphic available
Description	Inward rectifier potassium channel 2 (Potassium channel, inwardly rectifying subfamily J member 2) (Inward rectifier K(+) channel Kir2.1) (Cardiac inward rectifier potassium channel) (IRK1).

IRK2_MOUSE
θ value	6.88961 (rank : 6)	NC score	0.009506 (rank : 5)
Query Neighborhood Hits	7	Target Neighborhood Hits	46	Shared Neighborhood Hits	3
SwissProt Accessions	P35561	Gene names	Kcnj2, Irk1
Domain Architecture
Description	Inward rectifier potassium channel 2 (Potassium channel, inwardly rectifying subfamily J member 2) (Inward rectifier K(+) channel Kir2.1).

CAC1B_MOUSE
θ value	8.99809 (rank : 7)	NC score	0.005303 (rank : 7)
Query Neighborhood Hits	7	Target Neighborhood Hits	351	Shared Neighborhood Hits	2
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

Hits sorted by NC score

PUR8_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	7	Target Neighborhood Hits	7	Shared Neighborhood Hits	7
SwissProt Accessions	P54822	Gene names	Adsl, Adl
Domain Architecture
Description	Adenylosuccinate lyase (EC 4.3.2.2) (Adenylosuccinase) (ASL) (ASASE).

PUR8_HUMAN
NC score	0.998076 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	7	Target Neighborhood Hits	9	Shared Neighborhood Hits	4
SwissProt Accessions	P30566, O75495, Q5TI34	Gene names	ADSL, AMPS
Domain Architecture
Description	Adenylosuccinate lyase (EC 4.3.2.2) (Adenylosuccinase) (ASL) (ASASE).

FUMH_HUMAN
NC score	0.261225 (rank : 3)	θ value	0.000121331 (rank : 3)
Query Neighborhood Hits	7	Target Neighborhood Hits	7	Shared Neighborhood Hits	4
SwissProt Accessions	P07954	Gene names	FH
Domain Architecture
Description	Fumarate hydratase, mitochondrial precursor (EC 4.2.1.2) (Fumarase).

FUMH_MOUSE
NC score	0.260822 (rank : 4)	θ value	0.000158464 (rank : 4)
Query Neighborhood Hits	7	Target Neighborhood Hits	10	Shared Neighborhood Hits	4
SwissProt Accessions	P97807, Q99JL0, Q9DCX0	Gene names	Fh, Fh1
Domain Architecture
Description	Fumarate hydratase, mitochondrial precursor (EC 4.2.1.2) (Fumarase) (EF-3).

IRK2_MOUSE
NC score	0.009506 (rank : 5)	θ value	6.88961 (rank : 6)
Query Neighborhood Hits	7	Target Neighborhood Hits	46	Shared Neighborhood Hits	3
SwissProt Accessions	P35561	Gene names	Kcnj2, Irk1
Domain Architecture
Description	Inward rectifier potassium channel 2 (Potassium channel, inwardly rectifying subfamily J member 2) (Inward rectifier K(+) channel Kir2.1).

IRK2_HUMAN
NC score	0.009499 (rank : 6)	θ value	6.88961 (rank : 5)
Query Neighborhood Hits	7	Target Neighborhood Hits	47	Shared Neighborhood Hits	3
SwissProt Accessions	P63252, O15110, P48049	Gene names	KCNJ2, HIRK1
Domain Architecture	No domain graphic available
Description	Inward rectifier potassium channel 2 (Potassium channel, inwardly rectifying subfamily J member 2) (Inward rectifier K(+) channel Kir2.1) (Cardiac inward rectifier potassium channel) (IRK1).

CAC1B_MOUSE
NC score	0.005303 (rank : 7)	θ value	8.99809 (rank : 7)
Query Neighborhood Hits	7	Target Neighborhood Hits	351	Shared Neighborhood Hits	2
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).