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Network neighborhood for query Sequence : PUR8_HUMAN

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PUR8_HUMAN
SwissProt Accessions	P30566, O75495, Q5TI34	Gene names	ADSL, AMPS
Domain Architecture
Description	Adenylosuccinate lyase (EC 4.3.2.2) (Adenylosuccinase) (ASL) (ASASE).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PUR8_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	9	Target Neighborhood Hits	9	Shared Neighborhood Hits	9
SwissProt Accessions	P30566, O75495, Q5TI34	Gene names	ADSL, AMPS
Domain Architecture
Description	Adenylosuccinate lyase (EC 4.3.2.2) (Adenylosuccinase) (ASL) (ASASE).

PUR8_MOUSE
θ value	0 (rank : 2)	NC score	0.998076 (rank : 2)
Query Neighborhood Hits	9	Target Neighborhood Hits	7	Shared Neighborhood Hits	4
SwissProt Accessions	P54822	Gene names	Adsl, Adl
Domain Architecture
Description	Adenylosuccinate lyase (EC 4.3.2.2) (Adenylosuccinase) (ASL) (ASASE).

FUMH_MOUSE
θ value	0.00175202 (rank : 3)	NC score	0.237016 (rank : 4)
Query Neighborhood Hits	9	Target Neighborhood Hits	10	Shared Neighborhood Hits	4
SwissProt Accessions	P97807, Q99JL0, Q9DCX0	Gene names	Fh, Fh1
Domain Architecture
Description	Fumarate hydratase, mitochondrial precursor (EC 4.2.1.2) (Fumarase) (EF-3).

FUMH_HUMAN
θ value	0.00228821 (rank : 4)	NC score	0.237342 (rank : 3)
Query Neighborhood Hits	9	Target Neighborhood Hits	7	Shared Neighborhood Hits	4
SwissProt Accessions	P07954	Gene names	FH
Domain Architecture
Description	Fumarate hydratase, mitochondrial precursor (EC 4.2.1.2) (Fumarase).

IFIT5_HUMAN
θ value	0.813845 (rank : 5)	NC score	0.031706 (rank : 5)
Query Neighborhood Hits	9	Target Neighborhood Hits	44	Shared Neighborhood Hits	2
SwissProt Accessions	Q13325	Gene names	IFIT5, RI58
Domain Architecture
Description	Interferon-induced protein with tetratricopeptide repeats 5 (IFIT-5) (Retinoic acid- and interferon-inducible 58 kDa protein).

PREX1_HUMAN
θ value	1.81305 (rank : 6)	NC score	0.018005 (rank : 6)
Query Neighborhood Hits	9	Target Neighborhood Hits	177	Shared Neighborhood Hits	2
SwissProt Accessions	Q8TCU6, Q5JS95, Q5JS96, Q69YL2, Q7Z2L9, Q9BQH0, Q9BX55, Q9H4Q6, Q9P2D2, Q9UGQ4	Gene names	PREX1, KIAA1415
Domain Architecture
Description	Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (P-Rex1 protein).

DMD_HUMAN
θ value	4.03905 (rank : 7)	NC score	0.008570 (rank : 7)
Query Neighborhood Hits	9	Target Neighborhood Hits	1135	Shared Neighborhood Hits	4
SwissProt Accessions	P11532, Q02295, Q14169, Q14170, Q5JYU0, Q7KZ48	Gene names	DMD
Domain Architecture
Description	Dystrophin.

MYH9_HUMAN
θ value	8.99809 (rank : 8)	NC score	0.003849 (rank : 9)
Query Neighborhood Hits	9	Target Neighborhood Hits	1762	Shared Neighborhood Hits	4
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

Hits sorted by NC score

PUR8_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	9	Target Neighborhood Hits	9	Shared Neighborhood Hits	9
SwissProt Accessions	P30566, O75495, Q5TI34	Gene names	ADSL, AMPS
Domain Architecture
Description	Adenylosuccinate lyase (EC 4.3.2.2) (Adenylosuccinase) (ASL) (ASASE).

PUR8_MOUSE
NC score	0.998076 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	9	Target Neighborhood Hits	7	Shared Neighborhood Hits	4
SwissProt Accessions	P54822	Gene names	Adsl, Adl
Domain Architecture
Description	Adenylosuccinate lyase (EC 4.3.2.2) (Adenylosuccinase) (ASL) (ASASE).

FUMH_HUMAN
NC score	0.237342 (rank : 3)	θ value	0.00228821 (rank : 4)
Query Neighborhood Hits	9	Target Neighborhood Hits	7	Shared Neighborhood Hits	4
SwissProt Accessions	P07954	Gene names	FH
Domain Architecture
Description	Fumarate hydratase, mitochondrial precursor (EC 4.2.1.2) (Fumarase).

FUMH_MOUSE
NC score	0.237016 (rank : 4)	θ value	0.00175202 (rank : 3)
Query Neighborhood Hits	9	Target Neighborhood Hits	10	Shared Neighborhood Hits	4
SwissProt Accessions	P97807, Q99JL0, Q9DCX0	Gene names	Fh, Fh1
Domain Architecture
Description	Fumarate hydratase, mitochondrial precursor (EC 4.2.1.2) (Fumarase) (EF-3).

IFIT5_HUMAN
NC score	0.031706 (rank : 5)	θ value	0.813845 (rank : 5)
Query Neighborhood Hits	9	Target Neighborhood Hits	44	Shared Neighborhood Hits	2
SwissProt Accessions	Q13325	Gene names	IFIT5, RI58
Domain Architecture
Description	Interferon-induced protein with tetratricopeptide repeats 5 (IFIT-5) (Retinoic acid- and interferon-inducible 58 kDa protein).

PREX1_HUMAN
NC score	0.018005 (rank : 6)	θ value	1.81305 (rank : 6)
Query Neighborhood Hits	9	Target Neighborhood Hits	177	Shared Neighborhood Hits	2
SwissProt Accessions	Q8TCU6, Q5JS95, Q5JS96, Q69YL2, Q7Z2L9, Q9BQH0, Q9BX55, Q9H4Q6, Q9P2D2, Q9UGQ4	Gene names	PREX1, KIAA1415
Domain Architecture
Description	Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (P-Rex1 protein).

DMD_HUMAN
NC score	0.008570 (rank : 7)	θ value	4.03905 (rank : 7)
Query Neighborhood Hits	9	Target Neighborhood Hits	1135	Shared Neighborhood Hits	4
SwissProt Accessions	P11532, Q02295, Q14169, Q14170, Q5JYU0, Q7KZ48	Gene names	DMD
Domain Architecture
Description	Dystrophin.

MYH9_HUMAN
NC score	0.003849 (rank : 9)	θ value	8.99809 (rank : 8)
Query Neighborhood Hits	9	Target Neighborhood Hits	1762	Shared Neighborhood Hits	4
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).