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Network neighborhood for query Sequence : PUR6_MOUSE

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PUR6_MOUSE
SwissProt Accessions	Q9DCL9	Gene names	Paics
Domain Architecture
Description	Multifunctional protein ADE2 [Includes: Phosphoribosylaminoimidazole- succinocarboxamide synthase (EC 6.3.2.6) (SAICAR synthetase); Phosphoribosylaminoimidazole carboxylase (EC 4.1.1.21) (AIR carboxylase) (AIRC)].
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PUR6_HUMAN
θ value	0 (rank : 1)	NC score	0.998170 (rank : 2)
Query Neighborhood Hits	14	Target Neighborhood Hits	6	Shared Neighborhood Hits	6
SwissProt Accessions	P22234	Gene names	PAICS, ADE2, AIRC, PAIS
Domain Architecture
Description	Multifunctional protein ADE2 [Includes: Phosphoribosylaminoimidazole- succinocarboxamide synthase (EC 6.3.2.6) (SAICAR synthetase); Phosphoribosylaminoimidazole carboxylase (EC 4.1.1.21) (AIR carboxylase) (AIRC)].

PUR6_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	14
SwissProt Accessions	Q9DCL9	Gene names	Paics
Domain Architecture
Description	Multifunctional protein ADE2 [Includes: Phosphoribosylaminoimidazole- succinocarboxamide synthase (EC 6.3.2.6) (SAICAR synthetase); Phosphoribosylaminoimidazole carboxylase (EC 4.1.1.21) (AIR carboxylase) (AIRC)].

HB2S_MOUSE
θ value	1.06291 (rank : 3)	NC score	0.027124 (rank : 5)
Query Neighborhood Hits	14	Target Neighborhood Hits	202	Shared Neighborhood Hits	7
SwissProt Accessions	P06345	Gene names	H2-Ab1
Domain Architecture
Description	H-2 class II histocompatibility antigen, A-S beta chain precursor.

HB2U_MOUSE
θ value	1.81305 (rank : 4)	NC score	0.026842 (rank : 6)
Query Neighborhood Hits	14	Target Neighborhood Hits	201	Shared Neighborhood Hits	7
SwissProt Accessions	P06344	Gene names
Domain Architecture	No domain graphic available
Description	H-2 class II histocompatibility antigen, A-U beta chain precursor.

ACSL5_MOUSE
θ value	3.0926 (rank : 5)	NC score	0.028869 (rank : 4)
Query Neighborhood Hits	14	Target Neighborhood Hits	32	Shared Neighborhood Hits	4
SwissProt Accessions	Q8JZR0	Gene names	Acsl5, Facl5
Domain Architecture
Description	Long-chain-fatty-acid--CoA ligase 5 (EC 6.2.1.3) (Long-chain acyl-CoA synthetase 5) (LACS 5).

HB2K_MOUSE
θ value	3.0926 (rank : 6)	NC score	0.025450 (rank : 7)
Query Neighborhood Hits	14	Target Neighborhood Hits	203	Shared Neighborhood Hits	7
SwissProt Accessions	P06343	Gene names	H2-Ab1
Domain Architecture
Description	H-2 class II histocompatibility antigen, A-K beta chain precursor.

UBR1_HUMAN
θ value	3.0926 (rank : 7)	NC score	0.028902 (rank : 3)
Query Neighborhood Hits	14	Target Neighborhood Hits	43	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IWV7, O60708, O75492, Q68DN9, Q8IWY6, Q96JY4	Gene names	UBR1
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3 component N-recognin-1 (EC 6.-.-.-) (Ubiquitin-protein ligase E3-alpha-1) (Ubiquitin-protein ligase E3- alpha-I).

HB2A_MOUSE
θ value	4.03905 (rank : 8)	NC score	0.024466 (rank : 8)
Query Neighborhood Hits	14	Target Neighborhood Hits	203	Shared Neighborhood Hits	7
SwissProt Accessions	P14483	Gene names	H2-Ab1, H2-iabeta
Domain Architecture
Description	H-2 class II histocompatibility antigen, A beta chain precursor.

HB2Q_MOUSE
θ value	4.03905 (rank : 9)	NC score	0.024249 (rank : 9)
Query Neighborhood Hits	14	Target Neighborhood Hits	204	Shared Neighborhood Hits	7
SwissProt Accessions	P06342, O19469	Gene names	H2-Ab1
Domain Architecture
Description	H-2 class II histocompatibility antigen, A-Q beta chain precursor.

STAB2_HUMAN
θ value	5.27518 (rank : 10)	NC score	0.010414 (rank : 14)
Query Neighborhood Hits	14	Target Neighborhood Hits	534	Shared Neighborhood Hits	3
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

ACSL5_HUMAN
θ value	6.88961 (rank : 11)	NC score	0.023245 (rank : 11)
Query Neighborhood Hits	14	Target Neighborhood Hits	30	Shared Neighborhood Hits	4
SwissProt Accessions	Q9ULC5, Q6UX44, Q9UIU4	Gene names	ACSL5, ACS5, FACL5
Domain Architecture
Description	Long-chain-fatty-acid--CoA ligase 5 (EC 6.2.1.3) (Long-chain acyl-CoA synthetase 5) (LACS 5).

HB2D_MOUSE
θ value	6.88961 (rank : 12)	NC score	0.023256 (rank : 10)
Query Neighborhood Hits	14	Target Neighborhood Hits	203	Shared Neighborhood Hits	7
SwissProt Accessions	P01921, O19456, O19457, O19458, Q31133, Q31138, Q31139	Gene names	H2-Ab1
Domain Architecture
Description	H-2 class II histocompatibility antigen, A-D beta chain precursor.

ING3_HUMAN
θ value	8.99809 (rank : 13)	NC score	0.016923 (rank : 13)
Query Neighborhood Hits	14	Target Neighborhood Hits	178	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NXR8, O60394, Q6GMT3, Q7Z762, Q969G0, Q96DT4, Q9HC99, Q9P081	Gene names	ING3
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 3 (p47ING3 protein).

ING3_MOUSE
θ value	8.99809 (rank : 14)	NC score	0.016945 (rank : 12)
Query Neighborhood Hits	14	Target Neighborhood Hits	177	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VEK6, Q99JS6, Q9ERB2	Gene names	Ing3
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 3 (p47ING3 protein).

Hits sorted by NC score

PUR6_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	14
SwissProt Accessions	Q9DCL9	Gene names	Paics
Domain Architecture
Description	Multifunctional protein ADE2 [Includes: Phosphoribosylaminoimidazole- succinocarboxamide synthase (EC 6.3.2.6) (SAICAR synthetase); Phosphoribosylaminoimidazole carboxylase (EC 4.1.1.21) (AIR carboxylase) (AIRC)].

PUR6_HUMAN
NC score	0.998170 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	14	Target Neighborhood Hits	6	Shared Neighborhood Hits	6
SwissProt Accessions	P22234	Gene names	PAICS, ADE2, AIRC, PAIS
Domain Architecture
Description	Multifunctional protein ADE2 [Includes: Phosphoribosylaminoimidazole- succinocarboxamide synthase (EC 6.3.2.6) (SAICAR synthetase); Phosphoribosylaminoimidazole carboxylase (EC 4.1.1.21) (AIR carboxylase) (AIRC)].

UBR1_HUMAN
NC score	0.028902 (rank : 3)	θ value	3.0926 (rank : 7)
Query Neighborhood Hits	14	Target Neighborhood Hits	43	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IWV7, O60708, O75492, Q68DN9, Q8IWY6, Q96JY4	Gene names	UBR1
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3 component N-recognin-1 (EC 6.-.-.-) (Ubiquitin-protein ligase E3-alpha-1) (Ubiquitin-protein ligase E3- alpha-I).

ACSL5_MOUSE
NC score	0.028869 (rank : 4)	θ value	3.0926 (rank : 5)
Query Neighborhood Hits	14	Target Neighborhood Hits	32	Shared Neighborhood Hits	4
SwissProt Accessions	Q8JZR0	Gene names	Acsl5, Facl5
Domain Architecture
Description	Long-chain-fatty-acid--CoA ligase 5 (EC 6.2.1.3) (Long-chain acyl-CoA synthetase 5) (LACS 5).

HB2S_MOUSE
NC score	0.027124 (rank : 5)	θ value	1.06291 (rank : 3)
Query Neighborhood Hits	14	Target Neighborhood Hits	202	Shared Neighborhood Hits	7
SwissProt Accessions	P06345	Gene names	H2-Ab1
Domain Architecture
Description	H-2 class II histocompatibility antigen, A-S beta chain precursor.

HB2U_MOUSE
NC score	0.026842 (rank : 6)	θ value	1.81305 (rank : 4)
Query Neighborhood Hits	14	Target Neighborhood Hits	201	Shared Neighborhood Hits	7
SwissProt Accessions	P06344	Gene names
Domain Architecture	No domain graphic available
Description	H-2 class II histocompatibility antigen, A-U beta chain precursor.

HB2K_MOUSE
NC score	0.025450 (rank : 7)	θ value	3.0926 (rank : 6)
Query Neighborhood Hits	14	Target Neighborhood Hits	203	Shared Neighborhood Hits	7
SwissProt Accessions	P06343	Gene names	H2-Ab1
Domain Architecture
Description	H-2 class II histocompatibility antigen, A-K beta chain precursor.

HB2A_MOUSE
NC score	0.024466 (rank : 8)	θ value	4.03905 (rank : 8)
Query Neighborhood Hits	14	Target Neighborhood Hits	203	Shared Neighborhood Hits	7
SwissProt Accessions	P14483	Gene names	H2-Ab1, H2-iabeta
Domain Architecture
Description	H-2 class II histocompatibility antigen, A beta chain precursor.

HB2Q_MOUSE
NC score	0.024249 (rank : 9)	θ value	4.03905 (rank : 9)
Query Neighborhood Hits	14	Target Neighborhood Hits	204	Shared Neighborhood Hits	7
SwissProt Accessions	P06342, O19469	Gene names	H2-Ab1
Domain Architecture
Description	H-2 class II histocompatibility antigen, A-Q beta chain precursor.

HB2D_MOUSE
NC score	0.023256 (rank : 10)	θ value	6.88961 (rank : 12)
Query Neighborhood Hits	14	Target Neighborhood Hits	203	Shared Neighborhood Hits	7
SwissProt Accessions	P01921, O19456, O19457, O19458, Q31133, Q31138, Q31139	Gene names	H2-Ab1
Domain Architecture
Description	H-2 class II histocompatibility antigen, A-D beta chain precursor.

ACSL5_HUMAN
NC score	0.023245 (rank : 11)	θ value	6.88961 (rank : 11)
Query Neighborhood Hits	14	Target Neighborhood Hits	30	Shared Neighborhood Hits	4
SwissProt Accessions	Q9ULC5, Q6UX44, Q9UIU4	Gene names	ACSL5, ACS5, FACL5
Domain Architecture
Description	Long-chain-fatty-acid--CoA ligase 5 (EC 6.2.1.3) (Long-chain acyl-CoA synthetase 5) (LACS 5).

ING3_MOUSE
NC score	0.016945 (rank : 12)	θ value	8.99809 (rank : 14)
Query Neighborhood Hits	14	Target Neighborhood Hits	177	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VEK6, Q99JS6, Q9ERB2	Gene names	Ing3
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 3 (p47ING3 protein).

ING3_HUMAN
NC score	0.016923 (rank : 13)	θ value	8.99809 (rank : 13)
Query Neighborhood Hits	14	Target Neighborhood Hits	178	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NXR8, O60394, Q6GMT3, Q7Z762, Q969G0, Q96DT4, Q9HC99, Q9P081	Gene names	ING3
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 3 (p47ING3 protein).

STAB2_HUMAN
NC score	0.010414 (rank : 14)	θ value	5.27518 (rank : 10)
Query Neighborhood Hits	14	Target Neighborhood Hits	534	Shared Neighborhood Hits	3
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].