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Network neighborhood for query Sequence : PI3R6_MOUSE

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PI3R6_MOUSE
SwissProt Accessions	Q3U6Q4, Q3TBT5, Q3UAY4, Q8K323	Gene names	Pik3r6
Domain Architecture	No domain graphic available
Description	Phosphoinositide 3-kinase regulatory subunit 6 (Phosphoinositide 3- kinase gamma adapter protein of 87 kDa) (p87 PI3K adapter protein) (p87PIKAP).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PI3R6_HUMAN
θ value	0 (rank : 1)	NC score	0.996163 (rank : 2)
Query Neighborhood Hits	15	Target Neighborhood Hits	16	Shared Neighborhood Hits	5
SwissProt Accessions	Q5UE93, Q658R3	Gene names	PIK3R6, C17orf38
Domain Architecture	No domain graphic available
Description	Phosphoinositide 3-kinase regulatory subunit 6 (Phosphoinositide 3- kinase gamma adapter protein of 87 kDa) (p87 PI3K adapter protein) (p87PIKAP).

PI3R6_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	15	Target Neighborhood Hits	15	Shared Neighborhood Hits	15
SwissProt Accessions	Q3U6Q4, Q3TBT5, Q3UAY4, Q8K323	Gene names	Pik3r6
Domain Architecture	No domain graphic available
Description	Phosphoinositide 3-kinase regulatory subunit 6 (Phosphoinositide 3- kinase gamma adapter protein of 87 kDa) (p87 PI3K adapter protein) (p87PIKAP).

PI3R5_MOUSE
θ value	7.80994e-28 (rank : 3)	NC score	0.648200 (rank : 3)
Query Neighborhood Hits	15	Target Neighborhood Hits	21	Shared Neighborhood Hits	4
SwissProt Accessions	Q5SW28, Q3TU01, Q3UDZ2, Q8C215, Q8CGQ7	Gene names	Pik3r5
Domain Architecture	No domain graphic available
Description	Phosphoinositide 3-kinase regulatory subunit 5 (PI3-kinase regulatory subunit 5) (PI3-kinase p101 subunit) (PtdIns-3-kinase p101) (p101- PI3K) (Phosphatidylinositol-4,5-bisphosphate 3-kinase regulatory subunit) (PtdIns-3-kinase regulatory subunit).

PI3R5_HUMAN
θ value	6.84181e-24 (rank : 4)	NC score	0.637191 (rank : 4)
Query Neighborhood Hits	15	Target Neighborhood Hits	24	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WYR1, Q5G936, Q5G938, Q5G939, Q8IZ23, Q9Y2Y2	Gene names	PIK3R5
Domain Architecture	No domain graphic available
Description	Phosphoinositide 3-kinase regulatory subunit 5 (PI3-kinase regulatory subunit 5) (PI3-kinase p101 subunit) (PtdIns-3-kinase p101) (p101- PI3K) (Phosphatidylinositol-4,5-bisphosphate 3-kinase regulatory subunit) (PtdIns-3-kinase regulatory subunit) (Protein FOAP-2).

FHOD1_MOUSE
θ value	0.279714 (rank : 5)	NC score	0.054494 (rank : 5)
Query Neighborhood Hits	15	Target Neighborhood Hits	217	Shared Neighborhood Hits	3
SwissProt Accessions	Q6P9Q4, Q8BMK2	Gene names	Fhod1, Fhos1
Domain Architecture	No domain graphic available
Description	FH1/FH2 domain-containing protein (Formin homolog overexpressed in spleen) (FHOS) (Formin homology 2 domain-containing protein 1).

TGFR1_HUMAN
θ value	2.36792 (rank : 6)	NC score	0.005999 (rank : 12)
Query Neighborhood Hits	15	Target Neighborhood Hits	755	Shared Neighborhood Hits	3
SwissProt Accessions	P36897	Gene names	TGFBR1
Domain Architecture
Description	TGF-beta receptor type-1 precursor (EC 2.7.11.30) (TGF-beta receptor type I) (TGFR-1) (TGF-beta type I receptor) (Serine/threonine-protein kinase receptor R4) (SKR4) (Activin receptor-like kinase 5) (ALK-5).

FGR_MOUSE
θ value	6.88961 (rank : 7)	NC score	0.001109 (rank : 15)
Query Neighborhood Hits	15	Target Neighborhood Hits	1069	Shared Neighborhood Hits	3
SwissProt Accessions	P14234, Q61404	Gene names	Fgr
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2) (P55-FGR) (C- FGR).

SEC20_HUMAN
θ value	6.88961 (rank : 8)	NC score	0.023784 (rank : 6)
Query Neighborhood Hits	15	Target Neighborhood Hits	200	Shared Neighborhood Hits	3
SwissProt Accessions	Q12981, O75622, O75623, O75624, Q6K044, Q96FG4	Gene names	BNIP1, NIP1, SEC20L, TRG8
Domain Architecture
Description	Vesicle transport protein SEC20 (BCL2/adenovirus E1B 19 kDa protein- interacting protein 1) (Transformation-related gene 8 protein) (TRG- 8).

SEC20_MOUSE
θ value	6.88961 (rank : 9)	NC score	0.020028 (rank : 10)
Query Neighborhood Hits	15	Target Neighborhood Hits	323	Shared Neighborhood Hits	3
SwissProt Accessions	Q6QD59, Q5M9M2	Gene names	Bnip1, Sec20, Sec20l
Domain Architecture	No domain graphic available
Description	Vesicle transport protein SEC20.

SPTN5_HUMAN
θ value	6.88961 (rank : 10)	NC score	0.005478 (rank : 13)
Query Neighborhood Hits	15	Target Neighborhood Hits	674	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NRC6	Gene names	SPTBN5, SPTBN4
Domain Architecture
Description	Spectrin beta chain, brain 4 (Spectrin, non-erythroid beta chain 4) (Beta-V spectrin) (BSPECV).

TERF2_HUMAN
θ value	6.88961 (rank : 11)	NC score	0.022045 (rank : 7)
Query Neighborhood Hits	15	Target Neighborhood Hits	102	Shared Neighborhood Hits	3
SwissProt Accessions	Q15554	Gene names	TERF2, TRF2
Domain Architecture
Description	Telomeric repeat-binding factor 2 (TTAGGG repeat-binding factor 2) (Telomeric DNA-binding protein).

GBX1_MOUSE
θ value	8.99809 (rank : 12)	NC score	0.003379 (rank : 14)
Query Neighborhood Hits	15	Target Neighborhood Hits	350	Shared Neighborhood Hits	2
SwissProt Accessions	P82976, Q8CGW5	Gene names	Gbx1
Domain Architecture	No domain graphic available
Description	Homeobox protein GBX-1 (Gastrulation and brain-specific homeobox protein 1).

K0090_HUMAN
θ value	8.99809 (rank : 13)	NC score	0.020060 (rank : 8)
Query Neighborhood Hits	15	Target Neighborhood Hits	16	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N766, Q14700, Q63HL0, Q63HL3, Q8NBH8	Gene names	KIAA0090
Domain Architecture	No domain graphic available
Description	Protein KIAA0090 precursor.

K0090_MOUSE
θ value	8.99809 (rank : 14)	NC score	0.020057 (rank : 9)
Query Neighborhood Hits	15	Target Neighborhood Hits	20	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C7X2, Q3TCG4, Q6ZQJ4, Q8K3W8	Gene names	Kiaa0090
Domain Architecture	No domain graphic available
Description	Protein KIAA0090 precursor.

TERF2_MOUSE
θ value	8.99809 (rank : 15)	NC score	0.019941 (rank : 11)
Query Neighborhood Hits	15	Target Neighborhood Hits	128	Shared Neighborhood Hits	3
SwissProt Accessions	O35144	Gene names	Terf2, Trf2
Domain Architecture
Description	Telomeric repeat-binding factor 2 (TTAGGG repeat-binding factor 2) (Telomeric DNA-binding protein).

Hits sorted by NC score

PI3R6_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	15	Target Neighborhood Hits	15	Shared Neighborhood Hits	15
SwissProt Accessions	Q3U6Q4, Q3TBT5, Q3UAY4, Q8K323	Gene names	Pik3r6
Domain Architecture	No domain graphic available
Description	Phosphoinositide 3-kinase regulatory subunit 6 (Phosphoinositide 3- kinase gamma adapter protein of 87 kDa) (p87 PI3K adapter protein) (p87PIKAP).

PI3R6_HUMAN
NC score	0.996163 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	15	Target Neighborhood Hits	16	Shared Neighborhood Hits	5
SwissProt Accessions	Q5UE93, Q658R3	Gene names	PIK3R6, C17orf38
Domain Architecture	No domain graphic available
Description	Phosphoinositide 3-kinase regulatory subunit 6 (Phosphoinositide 3- kinase gamma adapter protein of 87 kDa) (p87 PI3K adapter protein) (p87PIKAP).

PI3R5_MOUSE
NC score	0.648200 (rank : 3)	θ value	7.80994e-28 (rank : 3)
Query Neighborhood Hits	15	Target Neighborhood Hits	21	Shared Neighborhood Hits	4
SwissProt Accessions	Q5SW28, Q3TU01, Q3UDZ2, Q8C215, Q8CGQ7	Gene names	Pik3r5
Domain Architecture	No domain graphic available
Description	Phosphoinositide 3-kinase regulatory subunit 5 (PI3-kinase regulatory subunit 5) (PI3-kinase p101 subunit) (PtdIns-3-kinase p101) (p101- PI3K) (Phosphatidylinositol-4,5-bisphosphate 3-kinase regulatory subunit) (PtdIns-3-kinase regulatory subunit).

PI3R5_HUMAN
NC score	0.637191 (rank : 4)	θ value	6.84181e-24 (rank : 4)
Query Neighborhood Hits	15	Target Neighborhood Hits	24	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WYR1, Q5G936, Q5G938, Q5G939, Q8IZ23, Q9Y2Y2	Gene names	PIK3R5
Domain Architecture	No domain graphic available
Description	Phosphoinositide 3-kinase regulatory subunit 5 (PI3-kinase regulatory subunit 5) (PI3-kinase p101 subunit) (PtdIns-3-kinase p101) (p101- PI3K) (Phosphatidylinositol-4,5-bisphosphate 3-kinase regulatory subunit) (PtdIns-3-kinase regulatory subunit) (Protein FOAP-2).

FHOD1_MOUSE
NC score	0.054494 (rank : 5)	θ value	0.279714 (rank : 5)
Query Neighborhood Hits	15	Target Neighborhood Hits	217	Shared Neighborhood Hits	3
SwissProt Accessions	Q6P9Q4, Q8BMK2	Gene names	Fhod1, Fhos1
Domain Architecture	No domain graphic available
Description	FH1/FH2 domain-containing protein (Formin homolog overexpressed in spleen) (FHOS) (Formin homology 2 domain-containing protein 1).

SEC20_HUMAN
NC score	0.023784 (rank : 6)	θ value	6.88961 (rank : 8)
Query Neighborhood Hits	15	Target Neighborhood Hits	200	Shared Neighborhood Hits	3
SwissProt Accessions	Q12981, O75622, O75623, O75624, Q6K044, Q96FG4	Gene names	BNIP1, NIP1, SEC20L, TRG8
Domain Architecture
Description	Vesicle transport protein SEC20 (BCL2/adenovirus E1B 19 kDa protein- interacting protein 1) (Transformation-related gene 8 protein) (TRG- 8).

TERF2_HUMAN
NC score	0.022045 (rank : 7)	θ value	6.88961 (rank : 11)
Query Neighborhood Hits	15	Target Neighborhood Hits	102	Shared Neighborhood Hits	3
SwissProt Accessions	Q15554	Gene names	TERF2, TRF2
Domain Architecture
Description	Telomeric repeat-binding factor 2 (TTAGGG repeat-binding factor 2) (Telomeric DNA-binding protein).

K0090_HUMAN
NC score	0.020060 (rank : 8)	θ value	8.99809 (rank : 13)
Query Neighborhood Hits	15	Target Neighborhood Hits	16	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N766, Q14700, Q63HL0, Q63HL3, Q8NBH8	Gene names	KIAA0090
Domain Architecture	No domain graphic available
Description	Protein KIAA0090 precursor.

K0090_MOUSE
NC score	0.020057 (rank : 9)	θ value	8.99809 (rank : 14)
Query Neighborhood Hits	15	Target Neighborhood Hits	20	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C7X2, Q3TCG4, Q6ZQJ4, Q8K3W8	Gene names	Kiaa0090
Domain Architecture	No domain graphic available
Description	Protein KIAA0090 precursor.

SEC20_MOUSE
NC score	0.020028 (rank : 10)	θ value	6.88961 (rank : 9)
Query Neighborhood Hits	15	Target Neighborhood Hits	323	Shared Neighborhood Hits	3
SwissProt Accessions	Q6QD59, Q5M9M2	Gene names	Bnip1, Sec20, Sec20l
Domain Architecture	No domain graphic available
Description	Vesicle transport protein SEC20.

TERF2_MOUSE
NC score	0.019941 (rank : 11)	θ value	8.99809 (rank : 15)
Query Neighborhood Hits	15	Target Neighborhood Hits	128	Shared Neighborhood Hits	3
SwissProt Accessions	O35144	Gene names	Terf2, Trf2
Domain Architecture
Description	Telomeric repeat-binding factor 2 (TTAGGG repeat-binding factor 2) (Telomeric DNA-binding protein).

TGFR1_HUMAN
NC score	0.005999 (rank : 12)	θ value	2.36792 (rank : 6)
Query Neighborhood Hits	15	Target Neighborhood Hits	755	Shared Neighborhood Hits	3
SwissProt Accessions	P36897	Gene names	TGFBR1
Domain Architecture
Description	TGF-beta receptor type-1 precursor (EC 2.7.11.30) (TGF-beta receptor type I) (TGFR-1) (TGF-beta type I receptor) (Serine/threonine-protein kinase receptor R4) (SKR4) (Activin receptor-like kinase 5) (ALK-5).

SPTN5_HUMAN
NC score	0.005478 (rank : 13)	θ value	6.88961 (rank : 10)
Query Neighborhood Hits	15	Target Neighborhood Hits	674	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NRC6	Gene names	SPTBN5, SPTBN4
Domain Architecture
Description	Spectrin beta chain, brain 4 (Spectrin, non-erythroid beta chain 4) (Beta-V spectrin) (BSPECV).

GBX1_MOUSE
NC score	0.003379 (rank : 14)	θ value	8.99809 (rank : 12)
Query Neighborhood Hits	15	Target Neighborhood Hits	350	Shared Neighborhood Hits	2
SwissProt Accessions	P82976, Q8CGW5	Gene names	Gbx1
Domain Architecture	No domain graphic available
Description	Homeobox protein GBX-1 (Gastrulation and brain-specific homeobox protein 1).

FGR_MOUSE
NC score	0.001109 (rank : 15)	θ value	6.88961 (rank : 7)
Query Neighborhood Hits	15	Target Neighborhood Hits	1069	Shared Neighborhood Hits	3
SwissProt Accessions	P14234, Q61404	Gene names	Fgr
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2) (P55-FGR) (C- FGR).