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Network neighborhood for query Sequence : PEX12_MOUSE

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PEX12_MOUSE
SwissProt Accessions	Q8VC48	Gene names	Pex12
Domain Architecture
Description	Peroxisome assembly protein 12 (Peroxin-12).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PEX12_HUMAN
θ value	0 (rank : 1)	NC score	0.998615 (rank : 2)
Query Neighborhood Hits	38	Target Neighborhood Hits	32	Shared Neighborhood Hits	32
SwissProt Accessions	O00623	Gene names	PEX12, PAF3
Domain Architecture
Description	Peroxisome assembly protein 12 (Peroxin-12) (Peroxisome assembly factor 3) (PAF-3).

PEX12_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	38	Target Neighborhood Hits	38	Shared Neighborhood Hits	38
SwissProt Accessions	Q8VC48	Gene names	Pex12
Domain Architecture
Description	Peroxisome assembly protein 12 (Peroxin-12).

DTX3_MOUSE
θ value	0.00665767 (rank : 3)	NC score	0.165378 (rank : 3)
Query Neighborhood Hits	38	Target Neighborhood Hits	202	Shared Neighborhood Hits	23
SwissProt Accessions	Q80V91, Q9ER06	Gene names	Dtx3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3) (mDTX3).

DTX3_HUMAN
θ value	0.0193708 (rank : 4)	NC score	0.158630 (rank : 4)
Query Neighborhood Hits	38	Target Neighborhood Hits	198	Shared Neighborhood Hits	22
SwissProt Accessions	Q8N9I9, Q8NAU6, Q8NDS8	Gene names	DTX3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3).

NEUL1_HUMAN
θ value	0.0736092 (rank : 5)	NC score	0.138455 (rank : 5)
Query Neighborhood Hits	38	Target Neighborhood Hits	114	Shared Neighborhood Hits	9
SwissProt Accessions	O76050, Q5TDR2, Q5TDR3, Q8TAN0, Q9H463	Gene names	NEURL, NEURL1, RNF67
Domain Architecture	No domain graphic available
Description	Neuralized-like protein 1 (h-neuralized 1) (h-neu) (RING finger protein 67).

NEURL_MOUSE
θ value	0.0736092 (rank : 6)	NC score	0.138006 (rank : 6)
Query Neighborhood Hits	38	Target Neighborhood Hits	106	Shared Neighborhood Hits	8
SwissProt Accessions	Q923S6, Q91ZT6, Q9CWF1, Q9QWF1	Gene names	Neurl, Neurl1
Domain Architecture	No domain graphic available
Description	Neuralized-like protein 1 (m-neuralized 1) (m-neu1).

RFWD2_HUMAN
θ value	0.163984 (rank : 7)	NC score	0.090298 (rank : 12)
Query Neighborhood Hits	38	Target Neighborhood Hits	518	Shared Neighborhood Hits	29
SwissProt Accessions	Q8NHY2, Q6H103, Q9H6L7	Gene names	RFWD2, COP1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (hCOP1).

RFWD2_MOUSE
θ value	0.163984 (rank : 8)	NC score	0.090910 (rank : 11)
Query Neighborhood Hits	38	Target Neighborhood Hits	535	Shared Neighborhood Hits	30
SwissProt Accessions	Q9R1A8	Gene names	Rfwd2, Cop1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (mCOP1).

MDM4_HUMAN
θ value	0.279714 (rank : 9)	NC score	0.116614 (rank : 7)
Query Neighborhood Hits	38	Target Neighborhood Hits	37	Shared Neighborhood Hits	6
SwissProt Accessions	O15151, Q6GS18, Q8IV83	Gene names	MDM4, MDMX
Domain Architecture
Description	Mdm4 protein (p53-binding protein Mdm4) (Mdm2-like p53-binding protein) (Mdmx protein) (Double minute 4 protein).

BRE1B_HUMAN
θ value	0.365318 (rank : 10)	NC score	0.062638 (rank : 20)
Query Neighborhood Hits	38	Target Neighborhood Hits	1040	Shared Neighborhood Hits	24
SwissProt Accessions	O75150, Q6AHZ6, Q6N005, Q7L3T6, Q8N615, Q96T18, Q9BSV9, Q9HC82	Gene names	RNF40, BRE1B, KIAA0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40) (95 kDa retinoblastoma-associated protein) (RBP95).

BRE1B_MOUSE
θ value	0.365318 (rank : 11)	NC score	0.065077 (rank : 19)
Query Neighborhood Hits	38	Target Neighborhood Hits	970	Shared Neighborhood Hits	24
SwissProt Accessions	Q3U319, Q6ZQ75, Q8BJA1, Q8BY03, Q8CHX4	Gene names	Rnf40, Bre1b, Kiaa0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40).

MDM4_MOUSE
θ value	0.365318 (rank : 12)	NC score	0.108569 (rank : 8)
Query Neighborhood Hits	38	Target Neighborhood Hits	36	Shared Neighborhood Hits	8
SwissProt Accessions	O35618	Gene names	Mdm4, Mdmx
Domain Architecture
Description	Mdm4 protein (p53-binding protein Mdm4) (Mdm2-like p53-binding protein) (Mdmx protein) (Double minute 4 protein).

TRAF7_HUMAN
θ value	0.62314 (rank : 13)	NC score	0.059883 (rank : 24)
Query Neighborhood Hits	38	Target Neighborhood Hits	482	Shared Neighborhood Hits	26
SwissProt Accessions	Q6Q0C0, Q9H073	Gene names	TRAF7, RFWD1, RNF119
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7) (RING finger and WD repeat domain protein 1) (RING finger protein 119).

TRAF7_MOUSE
θ value	0.62314 (rank : 14)	NC score	0.060191 (rank : 23)
Query Neighborhood Hits	38	Target Neighborhood Hits	470	Shared Neighborhood Hits	24
SwissProt Accessions	Q922B6, Q99JV3	Gene names	Traf7
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7).

TRAF4_MOUSE
θ value	0.813845 (rank : 15)	NC score	0.074753 (rank : 17)
Query Neighborhood Hits	38	Target Neighborhood Hits	338	Shared Neighborhood Hits	23
SwissProt Accessions	Q61382	Gene names	Traf4, Cart1
Domain Architecture
Description	TNF receptor-associated factor 4 (Cysteine-rich motif associated to RING and Traf domains protein 1).

PZRN3_HUMAN
θ value	1.38821 (rank : 16)	NC score	0.060448 (rank : 22)
Query Neighborhood Hits	38	Target Neighborhood Hits	461	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

PZRN3_MOUSE
θ value	1.38821 (rank : 17)	NC score	0.060687 (rank : 21)
Query Neighborhood Hits	38	Target Neighborhood Hits	447	Shared Neighborhood Hits	26
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

TBCD8_MOUSE
θ value	1.81305 (rank : 18)	NC score	0.053897 (rank : 25)
Query Neighborhood Hits	38	Target Neighborhood Hits	64	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z1A9	Gene names	Tbc1d8, Hblp1, Vrp
Domain Architecture
Description	TBC1 domain family member 8 (Vascular Rab-GAP/TBC-containing protein) (BUB2-like protein 1).

TRIM2_HUMAN
θ value	1.81305 (rank : 19)	NC score	0.040321 (rank : 34)
Query Neighborhood Hits	38	Target Neighborhood Hits	330	Shared Neighborhood Hits	24
SwissProt Accessions	Q9C040, O60272, Q9BSI9, Q9UFZ1	Gene names	TRIM2, KIAA0517, RNF86
Domain Architecture
Description	Tripartite motif-containing protein 2 (RING finger protein 86).

TBCD8_HUMAN
θ value	2.36792 (rank : 20)	NC score	0.051520 (rank : 27)
Query Neighborhood Hits	38	Target Neighborhood Hits	65	Shared Neighborhood Hits	4
SwissProt Accessions	O95759, Q9UQ32	Gene names	TBC1D8, VRP
Domain Architecture
Description	TBC1 domain family member 8 (Vascular Rab-GAP/TBC-containing protein) (AD 3).

TOPRS_HUMAN
θ value	2.36792 (rank : 21)	NC score	0.092443 (rank : 10)
Query Neighborhood Hits	38	Target Neighborhood Hits	286	Shared Neighborhood Hits	27
SwissProt Accessions	Q9NS56, O43273, Q6P987, Q9NS55, Q9UNR9	Gene names	TOPORS, LUN, TP53BPL
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

TOPRS_MOUSE
θ value	2.36792 (rank : 22)	NC score	0.093565 (rank : 9)
Query Neighborhood Hits	38	Target Neighborhood Hits	263	Shared Neighborhood Hits	26
SwissProt Accessions	Q80Z37, Q3U5B5, Q3UPZ1, Q3USN3, Q3UZ55, Q8BXP2, Q8CFF5, Q8CGC8, Q920L3	Gene names	Topors
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

TRAF4_HUMAN
θ value	2.36792 (rank : 23)	NC score	0.067044 (rank : 18)
Query Neighborhood Hits	38	Target Neighborhood Hits	373	Shared Neighborhood Hits	26
SwissProt Accessions	Q9BUZ4, O75615, Q14848, Q2PJN8	Gene names	TRAF4, CART1, MLN62, RNF83
Domain Architecture
Description	TNF receptor-associated factor 4 (Cysteine-rich domain associated with RING and Traf domains protein 1) (Malignant 62) (RING finger protein 83).

TRIM2_MOUSE
θ value	2.36792 (rank : 24)	NC score	0.039008 (rank : 35)
Query Neighborhood Hits	38	Target Neighborhood Hits	331	Shared Neighborhood Hits	24
SwissProt Accessions	Q9ESN6, Q3UHP5, Q8C981	Gene names	Trim2, Narf
Domain Architecture
Description	Tripartite motif-containing protein 2 (Neural activity-related RING finger protein).

BRE1A_HUMAN
θ value	3.0926 (rank : 25)	NC score	0.051390 (rank : 28)
Query Neighborhood Hits	38	Target Neighborhood Hits	1071	Shared Neighborhood Hits	24
SwissProt Accessions	Q5VTR2, Q69YL5, Q6P527, Q8N3J4, Q96JD3, Q9H9Y7, Q9HA51, Q9NUR4, Q9NWQ3, Q9NX83	Gene names	RNF20, BRE1A
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (hBRE1) (RING finger protein 20).

BRE1A_MOUSE
θ value	3.0926 (rank : 26)	NC score	0.051718 (rank : 26)
Query Neighborhood Hits	38	Target Neighborhood Hits	1025	Shared Neighborhood Hits	24
SwissProt Accessions	Q5DTM8, Q3UT10, Q3V350, Q7TT11, Q8BKA8, Q8BKN8, Q8BUF7, Q8BVU4	Gene names	Rnf20, Bre1a, Kiaa4116
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (RING finger protein 20).

LNX1_MOUSE
θ value	3.0926 (rank : 27)	NC score	0.041700 (rank : 31)
Query Neighborhood Hits	38	Target Neighborhood Hits	377	Shared Neighborhood Hits	20
SwissProt Accessions	O70263, O70264, Q8BRI8, Q8CFR3	Gene names	Lnx1, Lnx
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-binding protein 1) (Ligand of Numb-protein X 1).

PEX10_HUMAN
θ value	3.0926 (rank : 28)	NC score	0.075207 (rank : 16)
Query Neighborhood Hits	38	Target Neighborhood Hits	255	Shared Neighborhood Hits	28
SwissProt Accessions	O60683, Q5T095, Q9BW90	Gene names	PEX10, RNF69
Domain Architecture
Description	Peroxisome assembly protein 10 (Peroxin-10) (Peroxisome biogenesis factor 10) (RING finger protein 69).

RNF41_HUMAN
θ value	4.03905 (rank : 29)	NC score	0.086670 (rank : 15)
Query Neighborhood Hits	38	Target Neighborhood Hits	226	Shared Neighborhood Hits	25
SwissProt Accessions	Q9H4P4, O75598	Gene names	RNF41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RNF41_MOUSE
θ value	4.03905 (rank : 30)	NC score	0.086730 (rank : 14)
Query Neighborhood Hits	38	Target Neighborhood Hits	224	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BH75, Q8BGJ2, Q8BMC9, Q8VEA2, Q9CRK6, Q9D568	Gene names	Rnf41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

DTX3L_HUMAN
θ value	5.27518 (rank : 31)	NC score	0.089780 (rank : 13)
Query Neighborhood Hits	38	Target Neighborhood Hits	187	Shared Neighborhood Hits	21
SwissProt Accessions	Q8TDB6	Gene names	DTX3L, BBAP
Domain Architecture
Description	Protein deltex 3-like protein (B-lymphoma- and BAL-associated protein) (Rhysin-2) (Rhysin2).

CX6A1_HUMAN
θ value	6.88961 (rank : 32)	NC score	0.022576 (rank : 36)
Query Neighborhood Hits	38	Target Neighborhood Hits	6	Shared Neighborhood Hits	2
SwissProt Accessions	P12074, O43714, Q32Q37	Gene names	COX6A1, COX6AL
Domain Architecture
Description	Cytochrome c oxidase polypeptide VIa-liver, mitochondrial precursor (EC 1.9.3.1).

GLYG_MOUSE
θ value	6.88961 (rank : 33)	NC score	0.018785 (rank : 37)
Query Neighborhood Hits	38	Target Neighborhood Hits	4	Shared Neighborhood Hits	2
SwissProt Accessions	Q9R062	Gene names	Gyg1, Gyg
Domain Architecture
Description	Glycogenin-1 (EC 2.4.1.186).

LNX1_HUMAN
θ value	6.88961 (rank : 34)	NC score	0.040645 (rank : 33)
Query Neighborhood Hits	38	Target Neighborhood Hits	379	Shared Neighborhood Hits	22
SwissProt Accessions	Q8TBB1, Q8N4C2, Q96MJ7, Q9BY20	Gene names	LNX1, LNX
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-protein X 1).

LNX2_HUMAN
θ value	6.88961 (rank : 35)	NC score	0.041090 (rank : 32)
Query Neighborhood Hits	38	Target Neighborhood Hits	389	Shared Neighborhood Hits	24
SwissProt Accessions	Q8N448, Q5W0P0, Q6ZMH2, Q96SH4	Gene names	LNX2, PDZRN1
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2) (PDZ domain- containing RING finger protein 1).

DYH11_HUMAN
θ value	8.99809 (rank : 36)	NC score	0.009055 (rank : 38)
Query Neighborhood Hits	38	Target Neighborhood Hits	234	Shared Neighborhood Hits	2
SwissProt Accessions	Q96DT5, Q9UJ82	Gene names	DNAH11
Domain Architecture
Description	Ciliary dynein heavy chain 11 (Axonemal beta dynein heavy chain 11).

PCGF2_HUMAN
θ value	8.99809 (rank : 37)	NC score	0.049472 (rank : 30)
Query Neighborhood Hits	38	Target Neighborhood Hits	222	Shared Neighborhood Hits	28
SwissProt Accessions	P35227	Gene names	PCGF2, MEL18, RNF110, ZNF144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144).

PCGF2_MOUSE
θ value	8.99809 (rank : 38)	NC score	0.049595 (rank : 29)
Query Neighborhood Hits	38	Target Neighborhood Hits	213	Shared Neighborhood Hits	28
SwissProt Accessions	P23798	Gene names	Pcgf2, Mel-18, Mel18, Rnf110, Zfp144, Znf144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144) (Zfp-144).

Hits sorted by NC score

PEX12_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	38	Target Neighborhood Hits	38	Shared Neighborhood Hits	38
SwissProt Accessions	Q8VC48	Gene names	Pex12
Domain Architecture
Description	Peroxisome assembly protein 12 (Peroxin-12).

PEX12_HUMAN
NC score	0.998615 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	38	Target Neighborhood Hits	32	Shared Neighborhood Hits	32
SwissProt Accessions	O00623	Gene names	PEX12, PAF3
Domain Architecture
Description	Peroxisome assembly protein 12 (Peroxin-12) (Peroxisome assembly factor 3) (PAF-3).

DTX3_MOUSE
NC score	0.165378 (rank : 3)	θ value	0.00665767 (rank : 3)
Query Neighborhood Hits	38	Target Neighborhood Hits	202	Shared Neighborhood Hits	23
SwissProt Accessions	Q80V91, Q9ER06	Gene names	Dtx3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3) (mDTX3).

DTX3_HUMAN
NC score	0.158630 (rank : 4)	θ value	0.0193708 (rank : 4)
Query Neighborhood Hits	38	Target Neighborhood Hits	198	Shared Neighborhood Hits	22
SwissProt Accessions	Q8N9I9, Q8NAU6, Q8NDS8	Gene names	DTX3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3).

NEUL1_HUMAN
NC score	0.138455 (rank : 5)	θ value	0.0736092 (rank : 5)
Query Neighborhood Hits	38	Target Neighborhood Hits	114	Shared Neighborhood Hits	9
SwissProt Accessions	O76050, Q5TDR2, Q5TDR3, Q8TAN0, Q9H463	Gene names	NEURL, NEURL1, RNF67
Domain Architecture	No domain graphic available
Description	Neuralized-like protein 1 (h-neuralized 1) (h-neu) (RING finger protein 67).

NEURL_MOUSE
NC score	0.138006 (rank : 6)	θ value	0.0736092 (rank : 6)
Query Neighborhood Hits	38	Target Neighborhood Hits	106	Shared Neighborhood Hits	8
SwissProt Accessions	Q923S6, Q91ZT6, Q9CWF1, Q9QWF1	Gene names	Neurl, Neurl1
Domain Architecture	No domain graphic available
Description	Neuralized-like protein 1 (m-neuralized 1) (m-neu1).

MDM4_HUMAN
NC score	0.116614 (rank : 7)	θ value	0.279714 (rank : 9)
Query Neighborhood Hits	38	Target Neighborhood Hits	37	Shared Neighborhood Hits	6
SwissProt Accessions	O15151, Q6GS18, Q8IV83	Gene names	MDM4, MDMX
Domain Architecture
Description	Mdm4 protein (p53-binding protein Mdm4) (Mdm2-like p53-binding protein) (Mdmx protein) (Double minute 4 protein).

MDM4_MOUSE
NC score	0.108569 (rank : 8)	θ value	0.365318 (rank : 12)
Query Neighborhood Hits	38	Target Neighborhood Hits	36	Shared Neighborhood Hits	8
SwissProt Accessions	O35618	Gene names	Mdm4, Mdmx
Domain Architecture
Description	Mdm4 protein (p53-binding protein Mdm4) (Mdm2-like p53-binding protein) (Mdmx protein) (Double minute 4 protein).

TOPRS_MOUSE
NC score	0.093565 (rank : 9)	θ value	2.36792 (rank : 22)
Query Neighborhood Hits	38	Target Neighborhood Hits	263	Shared Neighborhood Hits	26
SwissProt Accessions	Q80Z37, Q3U5B5, Q3UPZ1, Q3USN3, Q3UZ55, Q8BXP2, Q8CFF5, Q8CGC8, Q920L3	Gene names	Topors
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

TOPRS_HUMAN
NC score	0.092443 (rank : 10)	θ value	2.36792 (rank : 21)
Query Neighborhood Hits	38	Target Neighborhood Hits	286	Shared Neighborhood Hits	27
SwissProt Accessions	Q9NS56, O43273, Q6P987, Q9NS55, Q9UNR9	Gene names	TOPORS, LUN, TP53BPL
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

RFWD2_MOUSE
NC score	0.090910 (rank : 11)	θ value	0.163984 (rank : 8)
Query Neighborhood Hits	38	Target Neighborhood Hits	535	Shared Neighborhood Hits	30
SwissProt Accessions	Q9R1A8	Gene names	Rfwd2, Cop1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (mCOP1).

RFWD2_HUMAN
NC score	0.090298 (rank : 12)	θ value	0.163984 (rank : 7)
Query Neighborhood Hits	38	Target Neighborhood Hits	518	Shared Neighborhood Hits	29
SwissProt Accessions	Q8NHY2, Q6H103, Q9H6L7	Gene names	RFWD2, COP1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (hCOP1).

DTX3L_HUMAN
NC score	0.089780 (rank : 13)	θ value	5.27518 (rank : 31)
Query Neighborhood Hits	38	Target Neighborhood Hits	187	Shared Neighborhood Hits	21
SwissProt Accessions	Q8TDB6	Gene names	DTX3L, BBAP
Domain Architecture
Description	Protein deltex 3-like protein (B-lymphoma- and BAL-associated protein) (Rhysin-2) (Rhysin2).

RNF41_MOUSE
NC score	0.086730 (rank : 14)	θ value	4.03905 (rank : 30)
Query Neighborhood Hits	38	Target Neighborhood Hits	224	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BH75, Q8BGJ2, Q8BMC9, Q8VEA2, Q9CRK6, Q9D568	Gene names	Rnf41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RNF41_HUMAN
NC score	0.086670 (rank : 15)	θ value	4.03905 (rank : 29)
Query Neighborhood Hits	38	Target Neighborhood Hits	226	Shared Neighborhood Hits	25
SwissProt Accessions	Q9H4P4, O75598	Gene names	RNF41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

PEX10_HUMAN
NC score	0.075207 (rank : 16)	θ value	3.0926 (rank : 28)
Query Neighborhood Hits	38	Target Neighborhood Hits	255	Shared Neighborhood Hits	28
SwissProt Accessions	O60683, Q5T095, Q9BW90	Gene names	PEX10, RNF69
Domain Architecture
Description	Peroxisome assembly protein 10 (Peroxin-10) (Peroxisome biogenesis factor 10) (RING finger protein 69).

TRAF4_MOUSE
NC score	0.074753 (rank : 17)	θ value	0.813845 (rank : 15)
Query Neighborhood Hits	38	Target Neighborhood Hits	338	Shared Neighborhood Hits	23
SwissProt Accessions	Q61382	Gene names	Traf4, Cart1
Domain Architecture
Description	TNF receptor-associated factor 4 (Cysteine-rich motif associated to RING and Traf domains protein 1).

TRAF4_HUMAN
NC score	0.067044 (rank : 18)	θ value	2.36792 (rank : 23)
Query Neighborhood Hits	38	Target Neighborhood Hits	373	Shared Neighborhood Hits	26
SwissProt Accessions	Q9BUZ4, O75615, Q14848, Q2PJN8	Gene names	TRAF4, CART1, MLN62, RNF83
Domain Architecture
Description	TNF receptor-associated factor 4 (Cysteine-rich domain associated with RING and Traf domains protein 1) (Malignant 62) (RING finger protein 83).

BRE1B_MOUSE
NC score	0.065077 (rank : 19)	θ value	0.365318 (rank : 11)
Query Neighborhood Hits	38	Target Neighborhood Hits	970	Shared Neighborhood Hits	24
SwissProt Accessions	Q3U319, Q6ZQ75, Q8BJA1, Q8BY03, Q8CHX4	Gene names	Rnf40, Bre1b, Kiaa0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40).

BRE1B_HUMAN
NC score	0.062638 (rank : 20)	θ value	0.365318 (rank : 10)
Query Neighborhood Hits	38	Target Neighborhood Hits	1040	Shared Neighborhood Hits	24
SwissProt Accessions	O75150, Q6AHZ6, Q6N005, Q7L3T6, Q8N615, Q96T18, Q9BSV9, Q9HC82	Gene names	RNF40, BRE1B, KIAA0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40) (95 kDa retinoblastoma-associated protein) (RBP95).

PZRN3_MOUSE
NC score	0.060687 (rank : 21)	θ value	1.38821 (rank : 17)
Query Neighborhood Hits	38	Target Neighborhood Hits	447	Shared Neighborhood Hits	26
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

PZRN3_HUMAN
NC score	0.060448 (rank : 22)	θ value	1.38821 (rank : 16)
Query Neighborhood Hits	38	Target Neighborhood Hits	461	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

TRAF7_MOUSE
NC score	0.060191 (rank : 23)	θ value	0.62314 (rank : 14)
Query Neighborhood Hits	38	Target Neighborhood Hits	470	Shared Neighborhood Hits	24
SwissProt Accessions	Q922B6, Q99JV3	Gene names	Traf7
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7).

TRAF7_HUMAN
NC score	0.059883 (rank : 24)	θ value	0.62314 (rank : 13)
Query Neighborhood Hits	38	Target Neighborhood Hits	482	Shared Neighborhood Hits	26
SwissProt Accessions	Q6Q0C0, Q9H073	Gene names	TRAF7, RFWD1, RNF119
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7) (RING finger and WD repeat domain protein 1) (RING finger protein 119).

TBCD8_MOUSE
NC score	0.053897 (rank : 25)	θ value	1.81305 (rank : 18)
Query Neighborhood Hits	38	Target Neighborhood Hits	64	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z1A9	Gene names	Tbc1d8, Hblp1, Vrp
Domain Architecture
Description	TBC1 domain family member 8 (Vascular Rab-GAP/TBC-containing protein) (BUB2-like protein 1).

BRE1A_MOUSE
NC score	0.051718 (rank : 26)	θ value	3.0926 (rank : 26)
Query Neighborhood Hits	38	Target Neighborhood Hits	1025	Shared Neighborhood Hits	24
SwissProt Accessions	Q5DTM8, Q3UT10, Q3V350, Q7TT11, Q8BKA8, Q8BKN8, Q8BUF7, Q8BVU4	Gene names	Rnf20, Bre1a, Kiaa4116
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (RING finger protein 20).

TBCD8_HUMAN
NC score	0.051520 (rank : 27)	θ value	2.36792 (rank : 20)
Query Neighborhood Hits	38	Target Neighborhood Hits	65	Shared Neighborhood Hits	4
SwissProt Accessions	O95759, Q9UQ32	Gene names	TBC1D8, VRP
Domain Architecture
Description	TBC1 domain family member 8 (Vascular Rab-GAP/TBC-containing protein) (AD 3).

BRE1A_HUMAN
NC score	0.051390 (rank : 28)	θ value	3.0926 (rank : 25)
Query Neighborhood Hits	38	Target Neighborhood Hits	1071	Shared Neighborhood Hits	24
SwissProt Accessions	Q5VTR2, Q69YL5, Q6P527, Q8N3J4, Q96JD3, Q9H9Y7, Q9HA51, Q9NUR4, Q9NWQ3, Q9NX83	Gene names	RNF20, BRE1A
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (hBRE1) (RING finger protein 20).

PCGF2_MOUSE
NC score	0.049595 (rank : 29)	θ value	8.99809 (rank : 38)
Query Neighborhood Hits	38	Target Neighborhood Hits	213	Shared Neighborhood Hits	28
SwissProt Accessions	P23798	Gene names	Pcgf2, Mel-18, Mel18, Rnf110, Zfp144, Znf144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144) (Zfp-144).

PCGF2_HUMAN
NC score	0.049472 (rank : 30)	θ value	8.99809 (rank : 37)
Query Neighborhood Hits	38	Target Neighborhood Hits	222	Shared Neighborhood Hits	28
SwissProt Accessions	P35227	Gene names	PCGF2, MEL18, RNF110, ZNF144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144).

LNX1_MOUSE
NC score	0.041700 (rank : 31)	θ value	3.0926 (rank : 27)
Query Neighborhood Hits	38	Target Neighborhood Hits	377	Shared Neighborhood Hits	20
SwissProt Accessions	O70263, O70264, Q8BRI8, Q8CFR3	Gene names	Lnx1, Lnx
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-binding protein 1) (Ligand of Numb-protein X 1).

LNX2_HUMAN
NC score	0.041090 (rank : 32)	θ value	6.88961 (rank : 35)
Query Neighborhood Hits	38	Target Neighborhood Hits	389	Shared Neighborhood Hits	24
SwissProt Accessions	Q8N448, Q5W0P0, Q6ZMH2, Q96SH4	Gene names	LNX2, PDZRN1
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2) (PDZ domain- containing RING finger protein 1).

LNX1_HUMAN
NC score	0.040645 (rank : 33)	θ value	6.88961 (rank : 34)
Query Neighborhood Hits	38	Target Neighborhood Hits	379	Shared Neighborhood Hits	22
SwissProt Accessions	Q8TBB1, Q8N4C2, Q96MJ7, Q9BY20	Gene names	LNX1, LNX
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-protein X 1).

TRIM2_HUMAN
NC score	0.040321 (rank : 34)	θ value	1.81305 (rank : 19)
Query Neighborhood Hits	38	Target Neighborhood Hits	330	Shared Neighborhood Hits	24
SwissProt Accessions	Q9C040, O60272, Q9BSI9, Q9UFZ1	Gene names	TRIM2, KIAA0517, RNF86
Domain Architecture
Description	Tripartite motif-containing protein 2 (RING finger protein 86).

TRIM2_MOUSE
NC score	0.039008 (rank : 35)	θ value	2.36792 (rank : 24)
Query Neighborhood Hits	38	Target Neighborhood Hits	331	Shared Neighborhood Hits	24
SwissProt Accessions	Q9ESN6, Q3UHP5, Q8C981	Gene names	Trim2, Narf
Domain Architecture
Description	Tripartite motif-containing protein 2 (Neural activity-related RING finger protein).

CX6A1_HUMAN
NC score	0.022576 (rank : 36)	θ value	6.88961 (rank : 32)
Query Neighborhood Hits	38	Target Neighborhood Hits	6	Shared Neighborhood Hits	2
SwissProt Accessions	P12074, O43714, Q32Q37	Gene names	COX6A1, COX6AL
Domain Architecture
Description	Cytochrome c oxidase polypeptide VIa-liver, mitochondrial precursor (EC 1.9.3.1).

GLYG_MOUSE
NC score	0.018785 (rank : 37)	θ value	6.88961 (rank : 33)
Query Neighborhood Hits	38	Target Neighborhood Hits	4	Shared Neighborhood Hits	2
SwissProt Accessions	Q9R062	Gene names	Gyg1, Gyg
Domain Architecture
Description	Glycogenin-1 (EC 2.4.1.186).

DYH11_HUMAN
NC score	0.009055 (rank : 38)	θ value	8.99809 (rank : 36)
Query Neighborhood Hits	38	Target Neighborhood Hits	234	Shared Neighborhood Hits	2
SwissProt Accessions	Q96DT5, Q9UJ82	Gene names	DNAH11
Domain Architecture
Description	Ciliary dynein heavy chain 11 (Axonemal beta dynein heavy chain 11).