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Network neighborhood for query Sequence : PCMD2_HUMAN

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PCMD2_HUMAN
SwissProt Accessions	Q9NV79, Q8IW60, Q9H4K2	Gene names	PCMTD2, C20orf36
Domain Architecture
Description	Protein-L-isoaspartate O-methyltransferase domain-containing protein 2.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PCMD2_HUMAN
θ value	8.00302e-174 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NV79, Q8IW60, Q9H4K2	Gene names	PCMTD2, C20orf36
Domain Architecture
Description	Protein-L-isoaspartate O-methyltransferase domain-containing protein 2.

PCMD2_MOUSE
θ value	3.25673e-167 (rank : 2)	NC score	0.999690 (rank : 2)
Query Neighborhood Hits	14	Target Neighborhood Hits	13	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BHD8, Q3UKB7, Q8BJT6, Q8BK38, Q8C0H6, Q8R1D5	Gene names	Pcmtd2
Domain Architecture
Description	Protein-L-isoaspartate O-methyltransferase domain-containing protein 2.

PCMD1_HUMAN
θ value	9.58617e-127 (rank : 3)	NC score	0.993469 (rank : 4)
Query Neighborhood Hits	14	Target Neighborhood Hits	13	Shared Neighborhood Hits	11
SwissProt Accessions	Q96MG8, Q96FK9	Gene names	PCMTD1
Domain Architecture
Description	Protein-L-isoaspartate O-methyltransferase domain-containing protein 1.

PCMD1_MOUSE
θ value	1.17183e-124 (rank : 4)	NC score	0.993483 (rank : 3)
Query Neighborhood Hits	14	Target Neighborhood Hits	13	Shared Neighborhood Hits	11
SwissProt Accessions	P59913	Gene names	Pcmtd1
Domain Architecture
Description	Protein-L-isoaspartate O-methyltransferase domain-containing protein 1.

PIMT_MOUSE
θ value	6.87365e-08 (rank : 5)	NC score	0.496733 (rank : 5)
Query Neighborhood Hits	14	Target Neighborhood Hits	13	Shared Neighborhood Hits	7
SwissProt Accessions	P23506, Q810R4	Gene names	Pcmt1
Domain Architecture
Description	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (EC 2.1.1.77) (Protein-beta-aspartate methyltransferase) (PIMT) (Protein L- isoaspartyl/D-aspartyl methyltransferase) (L-isoaspartyl protein carboxyl methyltransferase).

PIMT_HUMAN
θ value	1.99992e-07 (rank : 6)	NC score	0.490822 (rank : 6)
Query Neighborhood Hits	14	Target Neighborhood Hits	12	Shared Neighborhood Hits	7
SwissProt Accessions	P22061, Q14661, Q16556, Q93061, Q96II9, Q99625	Gene names	PCMT1
Domain Architecture
Description	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (EC 2.1.1.77) (Protein-beta-aspartate methyltransferase) (PIMT) (Protein L- isoaspartyl/D-aspartyl methyltransferase) (L-isoaspartyl protein carboxyl methyltransferase).

AS3MT_MOUSE
θ value	1.38821 (rank : 7)	NC score	0.070805 (rank : 8)
Query Neighborhood Hits	14	Target Neighborhood Hits	18	Shared Neighborhood Hits	7
SwissProt Accessions	Q91WU5, Q9QZT1	Gene names	As3mt, Cyt19
Domain Architecture	No domain graphic available
Description	Arsenite methyltransferase (EC 2.1.1.137) (S-adenosyl-L- methionine:arsenic(III) methyltransferase) (Methylarsonite methyltransferase).

TRM61_HUMAN
θ value	1.81305 (rank : 8)	NC score	0.098580 (rank : 7)
Query Neighborhood Hits	14	Target Neighborhood Hits	7	Shared Neighborhood Hits	6
SwissProt Accessions	Q96FX7, Q8N7Q9	Gene names	TRM61, C14orf172
Domain Architecture	No domain graphic available
Description	tRNA (adenine-N(1)-)-methyltransferase catalytic subunit TRM61 (EC 2.1.1.36) (tRNA(m1A58)-methyltransferase subunit TRM61) (tRNA(m1A58)MTase subunit TRM61).

FBRL_HUMAN
θ value	3.0926 (rank : 9)	NC score	0.065414 (rank : 10)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	6
SwissProt Accessions	P22087, O75259, Q9UPI6	Gene names	FBL, FIB1, FLRN
Domain Architecture
Description	rRNA 2'-O-methyltransferase fibrillarin (EC 2.1.1.-) (34 kDa nucleolar scleroderma antigen).

FBRL_MOUSE
θ value	3.0926 (rank : 10)	NC score	0.064303 (rank : 11)
Query Neighborhood Hits	14	Target Neighborhood Hits	22	Shared Neighborhood Hits	6
SwissProt Accessions	P35550, Q99L58	Gene names	Fbl
Domain Architecture
Description	rRNA 2'-O-methyltransferase fibrillarin (EC 2.1.1.-) (Nucleolar protein 1).

WNT6_HUMAN
θ value	4.03905 (rank : 11)	NC score	0.012736 (rank : 13)
Query Neighborhood Hits	14	Target Neighborhood Hits	52	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y6F9, Q9H1J6, Q9H238	Gene names	WNT6
Domain Architecture
Description	Protein Wnt-6 precursor.

WNT6_MOUSE
θ value	4.03905 (rank : 12)	NC score	0.012788 (rank : 12)
Query Neighborhood Hits	14	Target Neighborhood Hits	47	Shared Neighborhood Hits	4
SwissProt Accessions	P22727	Gene names	Wnt6, Wnt-6
Domain Architecture
Description	Protein Wnt-6 precursor.

ATS13_MOUSE
θ value	6.88961 (rank : 13)	NC score	0.005069 (rank : 14)
Query Neighborhood Hits	14	Target Neighborhood Hits	227	Shared Neighborhood Hits	2
SwissProt Accessions	Q769J6, Q76LW1	Gene names	Adamts13
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

TRM61_MOUSE
θ value	6.88961 (rank : 14)	NC score	0.065508 (rank : 9)
Query Neighborhood Hits	14	Target Neighborhood Hits	8	Shared Neighborhood Hits	6
SwissProt Accessions	Q80XC2, Q8BMD4, Q8BX33	Gene names	Trm61
Domain Architecture	No domain graphic available
Description	tRNA (adenine-N(1)-)-methyltransferase catalytic subunit TRM61 (EC 2.1.1.36) (tRNA(m1A58)-methyltransferase subunit TRM61) (tRNA(m1A58)MTase subunit TRM61).

Hits sorted by NC score

PCMD2_HUMAN
NC score	0.999962 (rank : 1)	θ value	8.00302e-174 (rank : 1)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NV79, Q8IW60, Q9H4K2	Gene names	PCMTD2, C20orf36
Domain Architecture
Description	Protein-L-isoaspartate O-methyltransferase domain-containing protein 2.

PCMD2_MOUSE
NC score	0.999690 (rank : 2)	θ value	3.25673e-167 (rank : 2)
Query Neighborhood Hits	14	Target Neighborhood Hits	13	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BHD8, Q3UKB7, Q8BJT6, Q8BK38, Q8C0H6, Q8R1D5	Gene names	Pcmtd2
Domain Architecture
Description	Protein-L-isoaspartate O-methyltransferase domain-containing protein 2.

PCMD1_MOUSE
NC score	0.993483 (rank : 3)	θ value	1.17183e-124 (rank : 4)
Query Neighborhood Hits	14	Target Neighborhood Hits	13	Shared Neighborhood Hits	11
SwissProt Accessions	P59913	Gene names	Pcmtd1
Domain Architecture
Description	Protein-L-isoaspartate O-methyltransferase domain-containing protein 1.

PCMD1_HUMAN
NC score	0.993469 (rank : 4)	θ value	9.58617e-127 (rank : 3)
Query Neighborhood Hits	14	Target Neighborhood Hits	13	Shared Neighborhood Hits	11
SwissProt Accessions	Q96MG8, Q96FK9	Gene names	PCMTD1
Domain Architecture
Description	Protein-L-isoaspartate O-methyltransferase domain-containing protein 1.

PIMT_MOUSE
NC score	0.496733 (rank : 5)	θ value	6.87365e-08 (rank : 5)
Query Neighborhood Hits	14	Target Neighborhood Hits	13	Shared Neighborhood Hits	7
SwissProt Accessions	P23506, Q810R4	Gene names	Pcmt1
Domain Architecture
Description	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (EC 2.1.1.77) (Protein-beta-aspartate methyltransferase) (PIMT) (Protein L- isoaspartyl/D-aspartyl methyltransferase) (L-isoaspartyl protein carboxyl methyltransferase).

PIMT_HUMAN
NC score	0.490822 (rank : 6)	θ value	1.99992e-07 (rank : 6)
Query Neighborhood Hits	14	Target Neighborhood Hits	12	Shared Neighborhood Hits	7
SwissProt Accessions	P22061, Q14661, Q16556, Q93061, Q96II9, Q99625	Gene names	PCMT1
Domain Architecture
Description	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (EC 2.1.1.77) (Protein-beta-aspartate methyltransferase) (PIMT) (Protein L- isoaspartyl/D-aspartyl methyltransferase) (L-isoaspartyl protein carboxyl methyltransferase).

TRM61_HUMAN
NC score	0.098580 (rank : 7)	θ value	1.81305 (rank : 8)
Query Neighborhood Hits	14	Target Neighborhood Hits	7	Shared Neighborhood Hits	6
SwissProt Accessions	Q96FX7, Q8N7Q9	Gene names	TRM61, C14orf172
Domain Architecture	No domain graphic available
Description	tRNA (adenine-N(1)-)-methyltransferase catalytic subunit TRM61 (EC 2.1.1.36) (tRNA(m1A58)-methyltransferase subunit TRM61) (tRNA(m1A58)MTase subunit TRM61).

AS3MT_MOUSE
NC score	0.070805 (rank : 8)	θ value	1.38821 (rank : 7)
Query Neighborhood Hits	14	Target Neighborhood Hits	18	Shared Neighborhood Hits	7
SwissProt Accessions	Q91WU5, Q9QZT1	Gene names	As3mt, Cyt19
Domain Architecture	No domain graphic available
Description	Arsenite methyltransferase (EC 2.1.1.137) (S-adenosyl-L- methionine:arsenic(III) methyltransferase) (Methylarsonite methyltransferase).

TRM61_MOUSE
NC score	0.065508 (rank : 9)	θ value	6.88961 (rank : 14)
Query Neighborhood Hits	14	Target Neighborhood Hits	8	Shared Neighborhood Hits	6
SwissProt Accessions	Q80XC2, Q8BMD4, Q8BX33	Gene names	Trm61
Domain Architecture	No domain graphic available
Description	tRNA (adenine-N(1)-)-methyltransferase catalytic subunit TRM61 (EC 2.1.1.36) (tRNA(m1A58)-methyltransferase subunit TRM61) (tRNA(m1A58)MTase subunit TRM61).

FBRL_HUMAN
NC score	0.065414 (rank : 10)	θ value	3.0926 (rank : 9)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	6
SwissProt Accessions	P22087, O75259, Q9UPI6	Gene names	FBL, FIB1, FLRN
Domain Architecture
Description	rRNA 2'-O-methyltransferase fibrillarin (EC 2.1.1.-) (34 kDa nucleolar scleroderma antigen).

FBRL_MOUSE
NC score	0.064303 (rank : 11)	θ value	3.0926 (rank : 10)
Query Neighborhood Hits	14	Target Neighborhood Hits	22	Shared Neighborhood Hits	6
SwissProt Accessions	P35550, Q99L58	Gene names	Fbl
Domain Architecture
Description	rRNA 2'-O-methyltransferase fibrillarin (EC 2.1.1.-) (Nucleolar protein 1).

WNT6_MOUSE
NC score	0.012788 (rank : 12)	θ value	4.03905 (rank : 12)
Query Neighborhood Hits	14	Target Neighborhood Hits	47	Shared Neighborhood Hits	4
SwissProt Accessions	P22727	Gene names	Wnt6, Wnt-6
Domain Architecture
Description	Protein Wnt-6 precursor.

WNT6_HUMAN
NC score	0.012736 (rank : 13)	θ value	4.03905 (rank : 11)
Query Neighborhood Hits	14	Target Neighborhood Hits	52	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y6F9, Q9H1J6, Q9H238	Gene names	WNT6
Domain Architecture
Description	Protein Wnt-6 precursor.

ATS13_MOUSE
NC score	0.005069 (rank : 14)	θ value	6.88961 (rank : 13)
Query Neighborhood Hits	14	Target Neighborhood Hits	227	Shared Neighborhood Hits	2
SwissProt Accessions	Q769J6, Q76LW1	Gene names	Adamts13
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).