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Network neighborhood for query Sequence : PCMD1_HUMAN

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PCMD1_HUMAN
SwissProt Accessions	Q96MG8, Q96FK9	Gene names	PCMTD1
Domain Architecture
Description	Protein-L-isoaspartate O-methyltransferase domain-containing protein 1.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PCMD1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	13	Target Neighborhood Hits	13	Shared Neighborhood Hits	13
SwissProt Accessions	Q96MG8, Q96FK9	Gene names	PCMTD1
Domain Architecture
Description	Protein-L-isoaspartate O-methyltransferase domain-containing protein 1.

PCMD1_MOUSE
θ value	5.52945e-183 (rank : 2)	NC score	0.999739 (rank : 2)
Query Neighborhood Hits	13	Target Neighborhood Hits	13	Shared Neighborhood Hits	11
SwissProt Accessions	P59913	Gene names	Pcmtd1
Domain Architecture
Description	Protein-L-isoaspartate O-methyltransferase domain-containing protein 1.

PCMD2_HUMAN
θ value	9.58617e-127 (rank : 3)	NC score	0.993469 (rank : 3)
Query Neighborhood Hits	13	Target Neighborhood Hits	14	Shared Neighborhood Hits	11
SwissProt Accessions	Q9NV79, Q8IW60, Q9H4K2	Gene names	PCMTD2, C20orf36
Domain Architecture
Description	Protein-L-isoaspartate O-methyltransferase domain-containing protein 2.

PCMD2_MOUSE
θ value	8.11517e-126 (rank : 4)	NC score	0.993176 (rank : 4)
Query Neighborhood Hits	13	Target Neighborhood Hits	13	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BHD8, Q3UKB7, Q8BJT6, Q8BK38, Q8C0H6, Q8R1D5	Gene names	Pcmtd2
Domain Architecture
Description	Protein-L-isoaspartate O-methyltransferase domain-containing protein 2.

PIMT_MOUSE
θ value	4.76016e-09 (rank : 5)	NC score	0.511254 (rank : 5)
Query Neighborhood Hits	13	Target Neighborhood Hits	13	Shared Neighborhood Hits	7
SwissProt Accessions	P23506, Q810R4	Gene names	Pcmt1
Domain Architecture
Description	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (EC 2.1.1.77) (Protein-beta-aspartate methyltransferase) (PIMT) (Protein L- isoaspartyl/D-aspartyl methyltransferase) (L-isoaspartyl protein carboxyl methyltransferase).

PIMT_HUMAN
θ value	6.21693e-09 (rank : 6)	NC score	0.506070 (rank : 6)
Query Neighborhood Hits	13	Target Neighborhood Hits	12	Shared Neighborhood Hits	7
SwissProt Accessions	P22061, Q14661, Q16556, Q93061, Q96II9, Q99625	Gene names	PCMT1
Domain Architecture
Description	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (EC 2.1.1.77) (Protein-beta-aspartate methyltransferase) (PIMT) (Protein L- isoaspartyl/D-aspartyl methyltransferase) (L-isoaspartyl protein carboxyl methyltransferase).

TRM61_HUMAN
θ value	0.813845 (rank : 7)	NC score	0.106869 (rank : 7)
Query Neighborhood Hits	13	Target Neighborhood Hits	7	Shared Neighborhood Hits	6
SwissProt Accessions	Q96FX7, Q8N7Q9	Gene names	TRM61, C14orf172
Domain Architecture	No domain graphic available
Description	tRNA (adenine-N(1)-)-methyltransferase catalytic subunit TRM61 (EC 2.1.1.36) (tRNA(m1A58)-methyltransferase subunit TRM61) (tRNA(m1A58)MTase subunit TRM61).

TRM61_MOUSE
θ value	3.0926 (rank : 8)	NC score	0.074392 (rank : 8)
Query Neighborhood Hits	13	Target Neighborhood Hits	8	Shared Neighborhood Hits	6
SwissProt Accessions	Q80XC2, Q8BMD4, Q8BX33	Gene names	Trm61
Domain Architecture	No domain graphic available
Description	tRNA (adenine-N(1)-)-methyltransferase catalytic subunit TRM61 (EC 2.1.1.36) (tRNA(m1A58)-methyltransferase subunit TRM61) (tRNA(m1A58)MTase subunit TRM61).

AS3MT_MOUSE
θ value	5.27518 (rank : 9)	NC score	0.062770 (rank : 9)
Query Neighborhood Hits	13	Target Neighborhood Hits	18	Shared Neighborhood Hits	7
SwissProt Accessions	Q91WU5, Q9QZT1	Gene names	As3mt, Cyt19
Domain Architecture	No domain graphic available
Description	Arsenite methyltransferase (EC 2.1.1.137) (S-adenosyl-L- methionine:arsenic(III) methyltransferase) (Methylarsonite methyltransferase).

FBRL_HUMAN
θ value	6.88961 (rank : 10)	NC score	0.055378 (rank : 10)
Query Neighborhood Hits	13	Target Neighborhood Hits	14	Shared Neighborhood Hits	6
SwissProt Accessions	P22087, O75259, Q9UPI6	Gene names	FBL, FIB1, FLRN
Domain Architecture
Description	rRNA 2'-O-methyltransferase fibrillarin (EC 2.1.1.-) (34 kDa nucleolar scleroderma antigen).

FBRL_MOUSE
θ value	6.88961 (rank : 11)	NC score	0.054430 (rank : 11)
Query Neighborhood Hits	13	Target Neighborhood Hits	22	Shared Neighborhood Hits	6
SwissProt Accessions	P35550, Q99L58	Gene names	Fbl
Domain Architecture
Description	rRNA 2'-O-methyltransferase fibrillarin (EC 2.1.1.-) (Nucleolar protein 1).

MINT_HUMAN
θ value	6.88961 (rank : 12)	NC score	0.006648 (rank : 13)
Query Neighborhood Hits	13	Target Neighborhood Hits	1291	Shared Neighborhood Hits	3
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

RFC1_HUMAN
θ value	8.99809 (rank : 13)	NC score	0.009744 (rank : 12)
Query Neighborhood Hits	13	Target Neighborhood Hits	352	Shared Neighborhood Hits	3
SwissProt Accessions	P35251, Q5XKF5, Q6PKU0, Q86V41, Q86V46	Gene names	RFC1, RFC140
Domain Architecture
Description	Replication factor C subunit 1 (Replication factor C large subunit) (RF-C 140 kDa subunit) (Activator 1 140 kDa subunit) (Activator 1 large subunit) (A1 140 kDa subunit) (DNA-binding protein PO-GA).

Hits sorted by NC score

PCMD1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	13	Target Neighborhood Hits	13	Shared Neighborhood Hits	13
SwissProt Accessions	Q96MG8, Q96FK9	Gene names	PCMTD1
Domain Architecture
Description	Protein-L-isoaspartate O-methyltransferase domain-containing protein 1.

PCMD1_MOUSE
NC score	0.999739 (rank : 2)	θ value	5.52945e-183 (rank : 2)
Query Neighborhood Hits	13	Target Neighborhood Hits	13	Shared Neighborhood Hits	11
SwissProt Accessions	P59913	Gene names	Pcmtd1
Domain Architecture
Description	Protein-L-isoaspartate O-methyltransferase domain-containing protein 1.

PCMD2_HUMAN
NC score	0.993469 (rank : 3)	θ value	9.58617e-127 (rank : 3)
Query Neighborhood Hits	13	Target Neighborhood Hits	14	Shared Neighborhood Hits	11
SwissProt Accessions	Q9NV79, Q8IW60, Q9H4K2	Gene names	PCMTD2, C20orf36
Domain Architecture
Description	Protein-L-isoaspartate O-methyltransferase domain-containing protein 2.

PCMD2_MOUSE
NC score	0.993176 (rank : 4)	θ value	8.11517e-126 (rank : 4)
Query Neighborhood Hits	13	Target Neighborhood Hits	13	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BHD8, Q3UKB7, Q8BJT6, Q8BK38, Q8C0H6, Q8R1D5	Gene names	Pcmtd2
Domain Architecture
Description	Protein-L-isoaspartate O-methyltransferase domain-containing protein 2.

PIMT_MOUSE
NC score	0.511254 (rank : 5)	θ value	4.76016e-09 (rank : 5)
Query Neighborhood Hits	13	Target Neighborhood Hits	13	Shared Neighborhood Hits	7
SwissProt Accessions	P23506, Q810R4	Gene names	Pcmt1
Domain Architecture
Description	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (EC 2.1.1.77) (Protein-beta-aspartate methyltransferase) (PIMT) (Protein L- isoaspartyl/D-aspartyl methyltransferase) (L-isoaspartyl protein carboxyl methyltransferase).

PIMT_HUMAN
NC score	0.506070 (rank : 6)	θ value	6.21693e-09 (rank : 6)
Query Neighborhood Hits	13	Target Neighborhood Hits	12	Shared Neighborhood Hits	7
SwissProt Accessions	P22061, Q14661, Q16556, Q93061, Q96II9, Q99625	Gene names	PCMT1
Domain Architecture
Description	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (EC 2.1.1.77) (Protein-beta-aspartate methyltransferase) (PIMT) (Protein L- isoaspartyl/D-aspartyl methyltransferase) (L-isoaspartyl protein carboxyl methyltransferase).

TRM61_HUMAN
NC score	0.106869 (rank : 7)	θ value	0.813845 (rank : 7)
Query Neighborhood Hits	13	Target Neighborhood Hits	7	Shared Neighborhood Hits	6
SwissProt Accessions	Q96FX7, Q8N7Q9	Gene names	TRM61, C14orf172
Domain Architecture	No domain graphic available
Description	tRNA (adenine-N(1)-)-methyltransferase catalytic subunit TRM61 (EC 2.1.1.36) (tRNA(m1A58)-methyltransferase subunit TRM61) (tRNA(m1A58)MTase subunit TRM61).

TRM61_MOUSE
NC score	0.074392 (rank : 8)	θ value	3.0926 (rank : 8)
Query Neighborhood Hits	13	Target Neighborhood Hits	8	Shared Neighborhood Hits	6
SwissProt Accessions	Q80XC2, Q8BMD4, Q8BX33	Gene names	Trm61
Domain Architecture	No domain graphic available
Description	tRNA (adenine-N(1)-)-methyltransferase catalytic subunit TRM61 (EC 2.1.1.36) (tRNA(m1A58)-methyltransferase subunit TRM61) (tRNA(m1A58)MTase subunit TRM61).

AS3MT_MOUSE
NC score	0.062770 (rank : 9)	θ value	5.27518 (rank : 9)
Query Neighborhood Hits	13	Target Neighborhood Hits	18	Shared Neighborhood Hits	7
SwissProt Accessions	Q91WU5, Q9QZT1	Gene names	As3mt, Cyt19
Domain Architecture	No domain graphic available
Description	Arsenite methyltransferase (EC 2.1.1.137) (S-adenosyl-L- methionine:arsenic(III) methyltransferase) (Methylarsonite methyltransferase).

FBRL_HUMAN
NC score	0.055378 (rank : 10)	θ value	6.88961 (rank : 10)
Query Neighborhood Hits	13	Target Neighborhood Hits	14	Shared Neighborhood Hits	6
SwissProt Accessions	P22087, O75259, Q9UPI6	Gene names	FBL, FIB1, FLRN
Domain Architecture
Description	rRNA 2'-O-methyltransferase fibrillarin (EC 2.1.1.-) (34 kDa nucleolar scleroderma antigen).

FBRL_MOUSE
NC score	0.054430 (rank : 11)	θ value	6.88961 (rank : 11)
Query Neighborhood Hits	13	Target Neighborhood Hits	22	Shared Neighborhood Hits	6
SwissProt Accessions	P35550, Q99L58	Gene names	Fbl
Domain Architecture
Description	rRNA 2'-O-methyltransferase fibrillarin (EC 2.1.1.-) (Nucleolar protein 1).

RFC1_HUMAN
NC score	0.009744 (rank : 12)	θ value	8.99809 (rank : 13)
Query Neighborhood Hits	13	Target Neighborhood Hits	352	Shared Neighborhood Hits	3
SwissProt Accessions	P35251, Q5XKF5, Q6PKU0, Q86V41, Q86V46	Gene names	RFC1, RFC140
Domain Architecture
Description	Replication factor C subunit 1 (Replication factor C large subunit) (RF-C 140 kDa subunit) (Activator 1 140 kDa subunit) (Activator 1 large subunit) (A1 140 kDa subunit) (DNA-binding protein PO-GA).

MINT_HUMAN
NC score	0.006648 (rank : 13)	θ value	6.88961 (rank : 12)
Query Neighborhood Hits	13	Target Neighborhood Hits	1291	Shared Neighborhood Hits	3
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).