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Network neighborhood for query Sequence : P2RX3_HUMAN

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P2RX3_HUMAN
SwissProt Accessions	P56373, Q9UQB6	Gene names	P2RX3
Domain Architecture
Description	P2X purinoceptor 3 (ATP receptor) (P2X3) (Purinergic receptor).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

P2RX3_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	12	Target Neighborhood Hits	12	Shared Neighborhood Hits	12
SwissProt Accessions	P56373, Q9UQB6	Gene names	P2RX3
Domain Architecture
Description	P2X purinoceptor 3 (ATP receptor) (P2X3) (Purinergic receptor).

P2RX4_HUMAN
θ value	1.26366e-94 (rank : 2)	NC score	0.988729 (rank : 2)
Query Neighborhood Hits	12	Target Neighborhood Hits	14	Shared Neighborhood Hits	10
SwissProt Accessions	Q99571, O00450, O14722, Q9UBG9	Gene names	P2RX4
Domain Architecture
Description	P2X purinoceptor 4 (ATP receptor) (P2X4) (Purinergic receptor).

P2RX2_HUMAN
θ value	3.44127e-92 (rank : 3)	NC score	0.972309 (rank : 8)
Query Neighborhood Hits	12	Target Neighborhood Hits	110	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UBL9, Q6V9R6, Q9NR37, Q9NR38, Q9UHD5, Q9UHD6, Q9UHD7, Q9Y637, Q9Y638	Gene names	P2RX2, P2X2
Domain Architecture
Description	P2X purinoceptor 2 (ATP receptor) (P2X2) (Purinergic receptor).

P2RX1_HUMAN
θ value	1.2666e-86 (rank : 4)	NC score	0.981026 (rank : 4)
Query Neighborhood Hits	12	Target Neighborhood Hits	11	Shared Neighborhood Hits	10
SwissProt Accessions	P51575, Q9UK84	Gene names	P2RX1, P2X1
Domain Architecture
Description	P2X purinoceptor 1 (ATP receptor) (P2X1) (Purinergic receptor).

P2RX1_MOUSE
θ value	1.44917e-82 (rank : 5)	NC score	0.980099 (rank : 5)
Query Neighborhood Hits	12	Target Neighborhood Hits	14	Shared Neighborhood Hits	10
SwissProt Accessions	P51576	Gene names	P2rx1
Domain Architecture
Description	P2X purinoceptor 1 (ATP receptor) (P2X1) (Purinergic receptor).

P2RX5_HUMAN
θ value	9.39325e-82 (rank : 6)	NC score	0.982701 (rank : 3)
Query Neighborhood Hits	12	Target Neighborhood Hits	12	Shared Neighborhood Hits	10
SwissProt Accessions	Q93086, O43450, O75540, Q93087, Q9NZV0	Gene names	P2RX5, P2X5
Domain Architecture
Description	P2X purinoceptor 5 (ATP receptor) (P2X5) (Purinergic receptor).

P2RX6_HUMAN
θ value	1.5519e-76 (rank : 7)	NC score	0.975805 (rank : 7)
Query Neighborhood Hits	12	Target Neighborhood Hits	10	Shared Neighborhood Hits	10
SwissProt Accessions	O15547, Q6IC33, Q9UL50	Gene names	P2RXL1, P2RX6, P2X6
Domain Architecture
Description	P2X purinoceptor 6 (ATP receptor) (P2X6) (Purinergic receptor) (P2XM) (Purinergic receptor P2X-like 1).

P2RX6_MOUSE
θ value	7.70199e-76 (rank : 8)	NC score	0.977407 (rank : 6)
Query Neighborhood Hits	12	Target Neighborhood Hits	10	Shared Neighborhood Hits	10
SwissProt Accessions	O54803	Gene names	P2rxl1, P2rx6
Domain Architecture
Description	P2X purinoceptor 6 (ATP receptor) (P2X6) (Purinergic receptor) (P2XM) (Purinergic receptor P2X-like 1).

P2RX7_MOUSE
θ value	5.34618e-69 (rank : 9)	NC score	0.954899 (rank : 9)
Query Neighborhood Hits	12	Target Neighborhood Hits	18	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Z1M0	Gene names	P2rx7, P2x7
Domain Architecture
Description	P2X purinoceptor 7 (ATP receptor) (P2X7) (Purinergic receptor) (P2Z receptor).

P2RX7_HUMAN
θ value	2.24614e-67 (rank : 10)	NC score	0.952068 (rank : 10)
Query Neighborhood Hits	12	Target Neighborhood Hits	14	Shared Neighborhood Hits	10
SwissProt Accessions	Q99572, O14991, Q96EV7	Gene names	P2RX7
Domain Architecture
Description	P2X purinoceptor 7 (ATP receptor) (P2X7) (Purinergic receptor) (P2Z receptor).

NOTC3_HUMAN
θ value	4.03905 (rank : 11)	NC score	0.000925 (rank : 12)
Query Neighborhood Hits	12	Target Neighborhood Hits	1062	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

KCAB3_HUMAN
θ value	8.99809 (rank : 12)	NC score	0.006041 (rank : 11)
Query Neighborhood Hits	12	Target Neighborhood Hits	28	Shared Neighborhood Hits	2
SwissProt Accessions	O43448	Gene names	KCNAB3, KCNA3B
Domain Architecture
Description	Voltage-gated potassium channel subunit beta-3 (K(+) channel subunit beta-3) (Kv-beta-3).

Hits sorted by NC score

P2RX3_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	12	Target Neighborhood Hits	12	Shared Neighborhood Hits	12
SwissProt Accessions	P56373, Q9UQB6	Gene names	P2RX3
Domain Architecture
Description	P2X purinoceptor 3 (ATP receptor) (P2X3) (Purinergic receptor).

P2RX4_HUMAN
NC score	0.988729 (rank : 2)	θ value	1.26366e-94 (rank : 2)
Query Neighborhood Hits	12	Target Neighborhood Hits	14	Shared Neighborhood Hits	10
SwissProt Accessions	Q99571, O00450, O14722, Q9UBG9	Gene names	P2RX4
Domain Architecture
Description	P2X purinoceptor 4 (ATP receptor) (P2X4) (Purinergic receptor).

P2RX5_HUMAN
NC score	0.982701 (rank : 3)	θ value	9.39325e-82 (rank : 6)
Query Neighborhood Hits	12	Target Neighborhood Hits	12	Shared Neighborhood Hits	10
SwissProt Accessions	Q93086, O43450, O75540, Q93087, Q9NZV0	Gene names	P2RX5, P2X5
Domain Architecture
Description	P2X purinoceptor 5 (ATP receptor) (P2X5) (Purinergic receptor).

P2RX1_HUMAN
NC score	0.981026 (rank : 4)	θ value	1.2666e-86 (rank : 4)
Query Neighborhood Hits	12	Target Neighborhood Hits	11	Shared Neighborhood Hits	10
SwissProt Accessions	P51575, Q9UK84	Gene names	P2RX1, P2X1
Domain Architecture
Description	P2X purinoceptor 1 (ATP receptor) (P2X1) (Purinergic receptor).

P2RX1_MOUSE
NC score	0.980099 (rank : 5)	θ value	1.44917e-82 (rank : 5)
Query Neighborhood Hits	12	Target Neighborhood Hits	14	Shared Neighborhood Hits	10
SwissProt Accessions	P51576	Gene names	P2rx1
Domain Architecture
Description	P2X purinoceptor 1 (ATP receptor) (P2X1) (Purinergic receptor).

P2RX6_MOUSE
NC score	0.977407 (rank : 6)	θ value	7.70199e-76 (rank : 8)
Query Neighborhood Hits	12	Target Neighborhood Hits	10	Shared Neighborhood Hits	10
SwissProt Accessions	O54803	Gene names	P2rxl1, P2rx6
Domain Architecture
Description	P2X purinoceptor 6 (ATP receptor) (P2X6) (Purinergic receptor) (P2XM) (Purinergic receptor P2X-like 1).

P2RX6_HUMAN
NC score	0.975805 (rank : 7)	θ value	1.5519e-76 (rank : 7)
Query Neighborhood Hits	12	Target Neighborhood Hits	10	Shared Neighborhood Hits	10
SwissProt Accessions	O15547, Q6IC33, Q9UL50	Gene names	P2RXL1, P2RX6, P2X6
Domain Architecture
Description	P2X purinoceptor 6 (ATP receptor) (P2X6) (Purinergic receptor) (P2XM) (Purinergic receptor P2X-like 1).

P2RX2_HUMAN
NC score	0.972309 (rank : 8)	θ value	3.44127e-92 (rank : 3)
Query Neighborhood Hits	12	Target Neighborhood Hits	110	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UBL9, Q6V9R6, Q9NR37, Q9NR38, Q9UHD5, Q9UHD6, Q9UHD7, Q9Y637, Q9Y638	Gene names	P2RX2, P2X2
Domain Architecture
Description	P2X purinoceptor 2 (ATP receptor) (P2X2) (Purinergic receptor).

P2RX7_MOUSE
NC score	0.954899 (rank : 9)	θ value	5.34618e-69 (rank : 9)
Query Neighborhood Hits	12	Target Neighborhood Hits	18	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Z1M0	Gene names	P2rx7, P2x7
Domain Architecture
Description	P2X purinoceptor 7 (ATP receptor) (P2X7) (Purinergic receptor) (P2Z receptor).

P2RX7_HUMAN
NC score	0.952068 (rank : 10)	θ value	2.24614e-67 (rank : 10)
Query Neighborhood Hits	12	Target Neighborhood Hits	14	Shared Neighborhood Hits	10
SwissProt Accessions	Q99572, O14991, Q96EV7	Gene names	P2RX7
Domain Architecture
Description	P2X purinoceptor 7 (ATP receptor) (P2X7) (Purinergic receptor) (P2Z receptor).

KCAB3_HUMAN
NC score	0.006041 (rank : 11)	θ value	8.99809 (rank : 12)
Query Neighborhood Hits	12	Target Neighborhood Hits	28	Shared Neighborhood Hits	2
SwissProt Accessions	O43448	Gene names	KCNAB3, KCNA3B
Domain Architecture
Description	Voltage-gated potassium channel subunit beta-3 (K(+) channel subunit beta-3) (Kv-beta-3).

NOTC3_HUMAN
NC score	0.000925 (rank : 12)	θ value	4.03905 (rank : 11)
Query Neighborhood Hits	12	Target Neighborhood Hits	1062	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].