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Network neighborhood for query Sequence : P2RX4_HUMAN

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P2RX4_HUMAN
SwissProt Accessions	Q99571, O00450, O14722, Q9UBG9	Gene names	P2RX4
Domain Architecture
Description	P2X purinoceptor 4 (ATP receptor) (P2X4) (Purinergic receptor).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

P2RX4_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	14
SwissProt Accessions	Q99571, O00450, O14722, Q9UBG9	Gene names	P2RX4
Domain Architecture
Description	P2X purinoceptor 4 (ATP receptor) (P2X4) (Purinergic receptor).

P2RX1_HUMAN
θ value	2.79562e-118 (rank : 2)	NC score	0.991494 (rank : 2)
Query Neighborhood Hits	14	Target Neighborhood Hits	11	Shared Neighborhood Hits	10
SwissProt Accessions	P51575, Q9UK84	Gene names	P2RX1, P2X1
Domain Architecture
Description	P2X purinoceptor 1 (ATP receptor) (P2X1) (Purinergic receptor).

P2RX1_MOUSE
θ value	9.94316e-116 (rank : 3)	NC score	0.990944 (rank : 3)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	10
SwissProt Accessions	P51576	Gene names	P2rx1
Domain Architecture
Description	P2X purinoceptor 1 (ATP receptor) (P2X1) (Purinergic receptor).

P2RX5_HUMAN
θ value	4.48402e-100 (rank : 4)	NC score	0.988325 (rank : 5)
Query Neighborhood Hits	14	Target Neighborhood Hits	12	Shared Neighborhood Hits	10
SwissProt Accessions	Q93086, O43450, O75540, Q93087, Q9NZV0	Gene names	P2RX5, P2X5
Domain Architecture
Description	P2X purinoceptor 5 (ATP receptor) (P2X5) (Purinergic receptor).

P2RX6_MOUSE
θ value	1.14293e-95 (rank : 5)	NC score	0.984936 (rank : 6)
Query Neighborhood Hits	14	Target Neighborhood Hits	10	Shared Neighborhood Hits	10
SwissProt Accessions	O54803	Gene names	P2rxl1, P2rx6
Domain Architecture
Description	P2X purinoceptor 6 (ATP receptor) (P2X6) (Purinergic receptor) (P2XM) (Purinergic receptor P2X-like 1).

P2RX2_HUMAN
θ value	9.6755e-95 (rank : 6)	NC score	0.973306 (rank : 8)
Query Neighborhood Hits	14	Target Neighborhood Hits	110	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UBL9, Q6V9R6, Q9NR37, Q9NR38, Q9UHD5, Q9UHD6, Q9UHD7, Q9Y637, Q9Y638	Gene names	P2RX2, P2X2
Domain Architecture
Description	P2X purinoceptor 2 (ATP receptor) (P2X2) (Purinergic receptor).

P2RX3_HUMAN
θ value	1.26366e-94 (rank : 7)	NC score	0.988729 (rank : 4)
Query Neighborhood Hits	14	Target Neighborhood Hits	12	Shared Neighborhood Hits	10
SwissProt Accessions	P56373, Q9UQB6	Gene names	P2RX3
Domain Architecture
Description	P2X purinoceptor 3 (ATP receptor) (P2X3) (Purinergic receptor).

P2RX6_HUMAN
θ value	1.06975e-93 (rank : 8)	NC score	0.982987 (rank : 7)
Query Neighborhood Hits	14	Target Neighborhood Hits	10	Shared Neighborhood Hits	10
SwissProt Accessions	O15547, Q6IC33, Q9UL50	Gene names	P2RXL1, P2RX6, P2X6
Domain Architecture
Description	P2X purinoceptor 6 (ATP receptor) (P2X6) (Purinergic receptor) (P2XM) (Purinergic receptor P2X-like 1).

P2RX7_MOUSE
θ value	4.49445e-92 (rank : 9)	NC score	0.966809 (rank : 9)
Query Neighborhood Hits	14	Target Neighborhood Hits	18	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Z1M0	Gene names	P2rx7, P2x7
Domain Architecture
Description	P2X purinoceptor 7 (ATP receptor) (P2X7) (Purinergic receptor) (P2Z receptor).

P2RX7_HUMAN
θ value	8.47616e-91 (rank : 10)	NC score	0.964438 (rank : 10)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	10
SwissProt Accessions	Q99572, O14991, Q96EV7	Gene names	P2RX7
Domain Architecture
Description	P2X purinoceptor 7 (ATP receptor) (P2X7) (Purinergic receptor) (P2Z receptor).

SMBT1_HUMAN
θ value	4.03905 (rank : 11)	NC score	0.008649 (rank : 12)
Query Neighborhood Hits	14	Target Neighborhood Hits	53	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UHJ3, Q96C73, Q9Y4Q9	Gene names	SFMBT1, RU1
Domain Architecture	No domain graphic available
Description	Scm-like with four MBT domains protein 1 (Renal ubiquitous protein 1).

GRIPE_MOUSE
θ value	5.27518 (rank : 12)	NC score	0.010078 (rank : 11)
Query Neighborhood Hits	14	Target Neighborhood Hits	70	Shared Neighborhood Hits	2
SwissProt Accessions	Q6GYP7, Q6GYP6, Q6ZQ28, Q8BNJ5, Q8C9G8, Q8CIW4, Q9JMC4	Gene names	Garnl1, Kiaa0884, Tulip1
Domain Architecture	No domain graphic available
Description	GTPase-activating RapGAP domain-like 1 (GAP-related-interacting partner to E12) (GRIPE) (Tuberin-like protein 1).

CASR_MOUSE
θ value	8.99809 (rank : 13)	NC score	0.002916 (rank : 14)
Query Neighborhood Hits	14	Target Neighborhood Hits	72	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QY96, O08968, O88519, Q9QY95, Q9QZU8, Q9R1D6, Q9R1Y2	Gene names	Casr, Gprc2a
Domain Architecture
Description	Extracellular calcium-sensing receptor precursor (CaSR) (Parathyroid Cell calcium-sensing receptor).

UCP4_HUMAN
θ value	8.99809 (rank : 14)	NC score	0.003947 (rank : 13)
Query Neighborhood Hits	14	Target Neighborhood Hits	58	Shared Neighborhood Hits	2
SwissProt Accessions	O95847	Gene names	SLC25A27, UCP4
Domain Architecture
Description	Mitochondrial uncoupling protein 4 (UCP 4) (Solute carrier family 25 member 27).

Hits sorted by NC score

P2RX4_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	14
SwissProt Accessions	Q99571, O00450, O14722, Q9UBG9	Gene names	P2RX4
Domain Architecture
Description	P2X purinoceptor 4 (ATP receptor) (P2X4) (Purinergic receptor).

P2RX1_HUMAN
NC score	0.991494 (rank : 2)	θ value	2.79562e-118 (rank : 2)
Query Neighborhood Hits	14	Target Neighborhood Hits	11	Shared Neighborhood Hits	10
SwissProt Accessions	P51575, Q9UK84	Gene names	P2RX1, P2X1
Domain Architecture
Description	P2X purinoceptor 1 (ATP receptor) (P2X1) (Purinergic receptor).

P2RX1_MOUSE
NC score	0.990944 (rank : 3)	θ value	9.94316e-116 (rank : 3)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	10
SwissProt Accessions	P51576	Gene names	P2rx1
Domain Architecture
Description	P2X purinoceptor 1 (ATP receptor) (P2X1) (Purinergic receptor).

P2RX3_HUMAN
NC score	0.988729 (rank : 4)	θ value	1.26366e-94 (rank : 7)
Query Neighborhood Hits	14	Target Neighborhood Hits	12	Shared Neighborhood Hits	10
SwissProt Accessions	P56373, Q9UQB6	Gene names	P2RX3
Domain Architecture
Description	P2X purinoceptor 3 (ATP receptor) (P2X3) (Purinergic receptor).

P2RX5_HUMAN
NC score	0.988325 (rank : 5)	θ value	4.48402e-100 (rank : 4)
Query Neighborhood Hits	14	Target Neighborhood Hits	12	Shared Neighborhood Hits	10
SwissProt Accessions	Q93086, O43450, O75540, Q93087, Q9NZV0	Gene names	P2RX5, P2X5
Domain Architecture
Description	P2X purinoceptor 5 (ATP receptor) (P2X5) (Purinergic receptor).

P2RX6_MOUSE
NC score	0.984936 (rank : 6)	θ value	1.14293e-95 (rank : 5)
Query Neighborhood Hits	14	Target Neighborhood Hits	10	Shared Neighborhood Hits	10
SwissProt Accessions	O54803	Gene names	P2rxl1, P2rx6
Domain Architecture
Description	P2X purinoceptor 6 (ATP receptor) (P2X6) (Purinergic receptor) (P2XM) (Purinergic receptor P2X-like 1).

P2RX6_HUMAN
NC score	0.982987 (rank : 7)	θ value	1.06975e-93 (rank : 8)
Query Neighborhood Hits	14	Target Neighborhood Hits	10	Shared Neighborhood Hits	10
SwissProt Accessions	O15547, Q6IC33, Q9UL50	Gene names	P2RXL1, P2RX6, P2X6
Domain Architecture
Description	P2X purinoceptor 6 (ATP receptor) (P2X6) (Purinergic receptor) (P2XM) (Purinergic receptor P2X-like 1).

P2RX2_HUMAN
NC score	0.973306 (rank : 8)	θ value	9.6755e-95 (rank : 6)
Query Neighborhood Hits	14	Target Neighborhood Hits	110	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UBL9, Q6V9R6, Q9NR37, Q9NR38, Q9UHD5, Q9UHD6, Q9UHD7, Q9Y637, Q9Y638	Gene names	P2RX2, P2X2
Domain Architecture
Description	P2X purinoceptor 2 (ATP receptor) (P2X2) (Purinergic receptor).

P2RX7_MOUSE
NC score	0.966809 (rank : 9)	θ value	4.49445e-92 (rank : 9)
Query Neighborhood Hits	14	Target Neighborhood Hits	18	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Z1M0	Gene names	P2rx7, P2x7
Domain Architecture
Description	P2X purinoceptor 7 (ATP receptor) (P2X7) (Purinergic receptor) (P2Z receptor).

P2RX7_HUMAN
NC score	0.964438 (rank : 10)	θ value	8.47616e-91 (rank : 10)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	10
SwissProt Accessions	Q99572, O14991, Q96EV7	Gene names	P2RX7
Domain Architecture
Description	P2X purinoceptor 7 (ATP receptor) (P2X7) (Purinergic receptor) (P2Z receptor).

GRIPE_MOUSE
NC score	0.010078 (rank : 11)	θ value	5.27518 (rank : 12)
Query Neighborhood Hits	14	Target Neighborhood Hits	70	Shared Neighborhood Hits	2
SwissProt Accessions	Q6GYP7, Q6GYP6, Q6ZQ28, Q8BNJ5, Q8C9G8, Q8CIW4, Q9JMC4	Gene names	Garnl1, Kiaa0884, Tulip1
Domain Architecture	No domain graphic available
Description	GTPase-activating RapGAP domain-like 1 (GAP-related-interacting partner to E12) (GRIPE) (Tuberin-like protein 1).

SMBT1_HUMAN
NC score	0.008649 (rank : 12)	θ value	4.03905 (rank : 11)
Query Neighborhood Hits	14	Target Neighborhood Hits	53	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UHJ3, Q96C73, Q9Y4Q9	Gene names	SFMBT1, RU1
Domain Architecture	No domain graphic available
Description	Scm-like with four MBT domains protein 1 (Renal ubiquitous protein 1).

UCP4_HUMAN
NC score	0.003947 (rank : 13)	θ value	8.99809 (rank : 14)
Query Neighborhood Hits	14	Target Neighborhood Hits	58	Shared Neighborhood Hits	2
SwissProt Accessions	O95847	Gene names	SLC25A27, UCP4
Domain Architecture
Description	Mitochondrial uncoupling protein 4 (UCP 4) (Solute carrier family 25 member 27).

CASR_MOUSE
NC score	0.002916 (rank : 14)	θ value	8.99809 (rank : 13)
Query Neighborhood Hits	14	Target Neighborhood Hits	72	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QY96, O08968, O88519, Q9QY95, Q9QZU8, Q9R1D6, Q9R1Y2	Gene names	Casr, Gprc2a
Domain Architecture
Description	Extracellular calcium-sensing receptor precursor (CaSR) (Parathyroid Cell calcium-sensing receptor).